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Ian Y. Chen, M.D., Ph.D. - Publications

Affiliations: 
2017- Cardiovascular Institute Stanford University School of Medicine, Palo Alto, CA, United States 
 2018- Cardiology Section VA Palo Alto Health Care System 
Area:
Cardiovascular imaging, valvular heart disease, stem cell biology
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45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Liu C, Shen M, Tan WLW, Chen IY, Liu Y, Yu X, Yang H, Zhang A, Liu Y, Zhao MT, Ameen M, Zhang M, Gross ER, Qi LS, Sayed N, et al. Statins improve endothelial function via suppression of epigenetic-driven EndMT. Nature Cardiovascular Research. 2: 467-485. PMID 37693816 DOI: 10.1038/s44161-023-00267-1  0.403
2022 Chen IY, Olshausen J, Thomas D, Lai C, McLaughlin TL, Wu JC. Generation of three induced pluripotent stem cell lines to model and investigate diseases affecting Hispanics. Stem Cell Research. 65: 102969. PMID 36427473 DOI: 10.1016/j.scr.2022.102969  0.369
2022 Shin HS, Thakore A, Tada Y, Pedroza AJ, Ikeda G, Chen IY, Chan D, Jaatinen KJ, Yajima S, Pfrender EM, Kawamura M, Yang PC, Wu JC, Appel EA, Fischbein MP, et al. Angiogenic stem cell delivery platform to augment post-infarction neovasculature and reverse ventricular remodeling. Scientific Reports. 12: 17605. PMID 36266453 DOI: 10.1038/s41598-022-21510-y  0.485
2022 Wei TT, Chandy M, Nishiga M, Zhang A, Kumar KK, Thomas D, Manhas A, Rhee S, Justesen JM, Chen IY, Wo HT, Khanamiri S, Yang JY, Seidl FJ, Burns NZ, et al. Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation. Cell. 185: 2387-2389. PMID 35750035 DOI: 10.1016/j.cell.2022.06.006  0.31
2022 Wei TT, Chandy M, Nishiga M, Zhang A, Kumar KK, Thomas D, Manhas A, Rhee S, Justesen JM, Chen IY, Wo HT, Khanamiri S, Yang JY, Seidl FJ, Burns NZ, et al. Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation. Cell. PMID 35489334 DOI: 10.1016/j.cell.2022.04.005  0.37
2022 Sallam K, Thomas D, Gaddam S, Lopez N, Beck A, Beach L, Rogers AJ, Zhang H, Chen IY, Ameen M, Hiesinger W, Teuteberg JJ, Rhee JW, Wang KC, Sayed N, et al. Modeling Effects of Immunosuppressive Drugs on Human Hearts Using Induced Pluripotent Stem Cell-Derived Cardiac Organoids and Single-Cell RNA Sequencing. Circulation. 145: 1367-1369. PMID 35467958 DOI: 10.1161/CIRCULATIONAHA.121.054317  0.403
2021 Tran MV, Marceau E, Lee PY, Chandy M, Chen IY. The Smoking Paradox: A Twist in the Tale of Vasospastic Angina. Journal of Vascular Medicine & Surgery. 9. PMID 36276915  0.557
2021 Tran MV, Marceau E, Liu Y, Sallam K, Medina P, Liu C, Sayed N, Muller MD, Liang DH, Chen IY. Coronary Artery Vasospasm Requiring Cardiac Autotransplantation Yet Controlled With Tobacco. Jacc. Case Reports. 3: 1177-1181. PMID 34401754 DOI: 10.1016/j.jaccas.2021.03.018  0.698
2021 Liu C, Medina P, Thomas D, Chen IY, Sallam K, Sayed D, Sayed N. A protocol for transdifferentiation of human cardiac fibroblasts into endothelial cells via activation of innate immunity. Star Protocols. 2: 100556. PMID 34151292 DOI: 10.1016/j.xpro.2021.100556  0.618
2020 Peterson KM, Franchi F, Olthoff M, Chen IY, Paulmurugan R, Rodriguez-Porcel M. Pathway-specific reporter genes to study stem cell biology. Stem Cells (Dayton, Ohio). PMID 32129537 DOI: 10.1002/Stem.3167  0.733
2019 Chandy M, Sayed N, Lau E, Liu C, Wei T, Chen IY, Thomas D, Rhee J, Oh B, Pepic L, Husain M, Quertermous T, Nallamshetty S, Wu J. Abstract 402: Adiponectin Receptor 3 is Associated With Endothelial Nitric Oxide Synthase Dysfunction and Predicts Insulin Resistance in South Asians Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.402  0.378
2019 Shudo Y, Jaatinen K, NIshiga M, Chen I, Greene C, Koyano T, Fong R, Boyd J, Lee A, Hiesinger W, Woo J. Comprehensive Analysis of Differential Expressed Genes Related with Myocardial Reverse Remodeling Following HeartWare Ventricular Assist Device Implantation The Journal of Heart and Lung Transplantation. 38: S244. DOI: 10.1016/J.Healun.2019.01.603  0.391
2018 Paik DT, Tian L, Lee J, Sayed N, Chen IY, Rhee S, Rhee JW, Kim Y, Wirka RC, Buikema JW, Wu SM, Red-Horse K, Quertermous T, Wu JC. Large-Scale Single-Cell RNA-Seq Reveals Molecular Signatures of Heterogeneous Populations of Human Induced Pluripotent Stem Cell-Derived Endothelial Cells. Circulation Research. PMID 29986945 DOI: 10.1161/Circresaha.118.312913  0.518
2016 Chen IY, Matsa E, Wu JC. Alternative approaches to generating cardiomyocytes are under development. Nature Reviews. Cardiology. PMID 27538813 DOI: 10.1038/Nrcardio.2016.130  0.373
2016 Chen IY, Wu JC. Finding Expandable Induced Cardiovascular Progenitor Cells. Circulation Research. 119: 16-20. PMID 27340267 DOI: 10.1161/Circresaha.116.308679  0.507
2016 Chen IY, Matsa E, Wu JC. Induced pluripotent stem cells: at the heart of cardiovascular precision medicine. Nature Reviews. Cardiology. PMID 27009425 DOI: 10.1038/Nrcardio.2016.36  0.449
2015 Ebert AD, Diecke S, Chen IY, Wu JC. Reprogramming and transdifferentiation for cardiovascular development and regenerative medicine: where do we stand? Embo Molecular Medicine. 7: 1090-103. PMID 26183451 DOI: 10.15252/Emmm.201504395  0.452
2014 Chen IY, Paulmurugan R, Nielsen CH, Wang DS, Chow V, Robbins RC, Gambhir SS. A titratable two-step transcriptional amplification strategy for targeted gene therapy based on ligand-induced intramolecular folding of a mutant human estrogen receptor. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 16: 224-34. PMID 23955099 DOI: 10.1007/S11307-013-0673-4  0.683
2013 Chen IY, Gheysens O, Li Z, Rasooly JA, Wang Q, Paulmurugan R, Rosenberg J, Rodriguez-Porcel M, Willmann JK, Wang DS, Contag CH, Robbins RC, Wu JC, Gambhir SS. Noninvasive imaging of hypoxia-inducible factor-1α gene therapy for myocardial ischemia. Human Gene Therapy Methods. 24: 279-88. PMID 23937265 DOI: 10.1089/Hgtb.2013.028  0.786
2013 Psaltis PJ, Peterson KM, Xu R, Franchi F, Witt T, Chen IY, Lerman A, Simari RD, Gambhir SS, Rodriguez-Porcel M. Noninvasive monitoring of oxidative stress in transplanted mesenchymal stromal cells. Jacc. Cardiovascular Imaging. 6: 795-802. PMID 23643284 DOI: 10.1016/J.Jcmg.2012.11.018  0.704
2013 Chen IY, Wu JC. Molecular imaging: the key to advancing cardiac stem cell therapy. Trends in Cardiovascular Medicine. 23: 201-10. PMID 23561794 DOI: 10.1016/J.Tcm.2012.12.003  0.545
2011 Chen IY, Wu JC. Cardiovascular molecular imaging: focus on clinical translation. Circulation. 123: 425-43. PMID 21282520 DOI: 10.1161/Circulationaha.109.916338  0.493
2011 Gheysens O, Chen IY, Rodriguez-Porcel M, Chan C, Rasooly J, Vaerenberg C, Paulmurugan R, Willmann JK, Deroose C, Wu J, Gambhir SS. Non-invasive bioluminescence imaging of myoblast-mediated hypoxia-inducible factor-1 alpha gene transfer. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 13: 1124-32. PMID 21267661 DOI: 10.1007/S11307-011-0471-9  0.762
2010 Patel MR, Chang YF, Chen IY, Bachmann MH, Yan X, Contag CH, Gambhir SS. Longitudinal, noninvasive imaging of T-cell effector function and proliferation in living subjects. Cancer Research. 70: 10141-9. PMID 21159636 DOI: 10.1158/0008-5472.Can-10-1843  0.796
2010 Chen IY, Gheysens O, Ray S, Wang Q, Padmanabhan P, Paulmurugan R, Loening AM, Rodriguez-Porcel M, Willmann JK, Sheikh AY, Nielsen CH, Hoyt G, Contag CH, Robbins RC, Biswal S, et al. Indirect imaging of cardiac-specific transgene expression using a bidirectional two-step transcriptional amplification strategy. Gene Therapy. 17: 827-38. PMID 20237511 DOI: 10.1038/Gt.2010.30  0.777
2010 Rodriguez-Porcel M, Gheysens O, Paulmurugan R, Chen IY, Peterson KM, Willmann JK, Wu JC, Zhu X, Lerman LO, Gambhir SS. Antioxidants improve early survival of cardiomyoblasts after transplantation to the myocardium. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 12: 325-34. PMID 20013064 DOI: 10.1007/S11307-009-0274-4  0.784
2009 Benoit MR, Mayer D, Barak Y, Chen IY, Hu W, Cheng Z, Wang SX, Spielman DM, Gambhir SS, Matin A. Visualizing implanted tumors in mice with magnetic resonance imaging using magnetotactic bacteria. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 5170-7. PMID 19671860 DOI: 10.1158/1078-0432.Ccr-08-3206  0.581
2009 Willmann JK, Paulmurugan R, Rodriguez-Porcel M, Stein W, Brinton TJ, Connolly AJ, Nielsen CH, Lutz AM, Lyons J, Ikeno F, Suzuki Y, Rosenberg J, Chen IY, Wu JC, Yeung AC, et al. Imaging gene expression in human mesenchymal stem cells: from small to large animals. Radiology. 252: 117-27. PMID 19366903 DOI: 10.1148/Radiol.2513081616  0.785
2009 Chen IY, Greve JM, Gheysens O, Willmann JK, Rodriguez-Porcel M, Chu P, Sheikh AY, Faranesh AZ, Paulmurugan R, Yang PC, Wu JC, Gambhir SS. Comparison of optical bioluminescence reporter gene and superparamagnetic iron oxide MR contrast agent as cell markers for noninvasive imaging of cardiac cell transplantation. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 11: 178-87. PMID 19034584 DOI: 10.1007/S11307-008-0182-Z  0.8
2008 Suzuki Y, Cunningham CH, Noguchi K, Chen IY, Weissman IL, Yeung AC, Robbins RC, Yang PC. In vivo serial evaluation of superparamagnetic iron-oxide labeled stem cells by off-resonance positive contrast. Magnetic Resonance in Medicine. 60: 1269-75. PMID 19030159 DOI: 10.1002/Mrm.21816  0.392
2008 Rodriguez-Porcel M, Cai W, Gheysens O, Willmann JK, Chen K, Wang H, Chen IY, He L, Wu JC, Li ZB, Mohamedali KA, Kim S, Rosenblum MG, Chen X, Gambhir SS. Imaging of VEGF receptor in a rat myocardial infarction model using PET. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 49: 667-73. PMID 18375924 DOI: 10.2967/Jnumed.107.040576  0.769
2008 Willmann JK, Chen K, Wang H, Paulmurugan R, Rollins M, Cai W, Wang DS, Chen IY, Gheysens O, Rodriguez-Porcel M, Chen X, Gambhir SS. Monitoring of the biological response to murine hindlimb ischemia with 64Cu-labeled vascular endothelial growth factor-121 positron emission tomography. Circulation. 117: 915-22. PMID 18250264 DOI: 10.1161/Circulationaha.107.733220  0.77
2008 Rodriguez-Porcel M, Brinton TJ, Chen IY, Gheysens O, Lyons J, Ikeno F, Willmann JK, Wu L, Wu JC, Yeung AC, Yock P, Gambhir SS. Reporter gene imaging following percutaneous delivery in swine moving toward clinical applications. Journal of the American College of Cardiology. 51: 595-7. PMID 18237691 DOI: 10.1016/J.Jacc.2007.08.063  0.782
2008 Willmann JK, Paulmurugan R, Chen K, Gheysens O, Rodriguez-Porcel M, Lutz AM, Chen IY, Chen X, Gambhir SS. US imaging of tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice. Radiology. 246: 508-18. PMID 18180339 DOI: 10.1148/Radiol.2462070536  0.78
2007 Kutschka I, Chen IY, Kofidis T, von Degenfeld G, Sheikh AY, Hendry SL, Hoyt G, Pearl J, Blau HM, Gambhir SS, Robbins RC. In vivo optical bioluminescence imaging of collagen-supported cardiac cell grafts. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society For Heart Transplantation. 26: 273-80. PMID 17346630 DOI: 10.1016/J.Healun.2006.11.604  0.572
2006 Kutschka I, Kofidis T, Chen IY, von Degenfeld G, Zwierzchoniewska M, Hoyt G, Arai T, Lebl DR, Hendry SL, Sheikh AY, Cooke DT, Connolly A, Blau HM, Gambhir SS, Robbins RC. Adenoviral human BCL-2 transgene expression attenuates early donor cell death after cardiomyoblast transplantation into ischemic rat hearts. Circulation. 114: I174-80. PMID 16820569 DOI: 10.1161/Circulationaha.105.001370  0.569
2006 Kutschka I, Chen IY, Kofidis T, Arai T, von Degenfeld G, Sheikh AY, Hendry SL, Pearl J, Hoyt G, Sista R, Yang PC, Blau HM, Gambhir SS, Robbins RC. Collagen matrices enhance survival of transplanted cardiomyoblasts and contribute to functional improvement of ischemic rat hearts. Circulation. 114: I167-73. PMID 16820568 DOI: 10.1161/Circulationaha.105.001297  0.537
2006 Gheysens O, Lin S, Cao F, Wang D, Chen IY, Rodriguez-Porcel M, Min JJ, Gambhir SS, Wu JC. Noninvasive evaluation of immunosuppressive drug efficacy on acute donor cell survival. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 8: 163-70. PMID 16555032 DOI: 10.1007/S11307-006-0038-3  0.792
2006 Wu JC, Spin JM, Cao F, Lin S, Xie X, Gheysens O, Chen IY, Sheikh AY, Robbins RC, Tsalenko A, Gambhir SS, Quertermous T. Transcriptional profiling of reporter genes used for molecular imaging of embryonic stem cell transplantation. Physiological Genomics. 25: 29-38. PMID 16390873 DOI: 10.1152/Physiolgenomics.00254.2005  0.754
2005 Rodriguez-Porcel M, Gheysens O, Chen IY, Wu JC, Gambhir SS. Image-guided cardiac cell delivery using high-resolution small-animal ultrasound. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 1142-7. PMID 16111921 DOI: 10.1016/J.Ymthe.2005.07.532  0.798
2004 Wu JC, Chen IY, Wang Y, Tseng JR, Chhabra A, Salek M, Min JJ, Fishbein MC, Crystal R, Gambhir SS. Molecular imaging of the kinetics of vascular endothelial growth factor gene expression in ischemic myocardium. Circulation. 110: 685-91. PMID 15302807 DOI: 10.1161/01.Cir.0000138153.02213.22  0.673
2004 Chen IY, Wu JC, Min JJ, Sundaresan G, Lewis X, Liang Q, Herschman HR, Gambhir SS. Micro-positron emission tomography imaging of cardiac gene expression in rats using bicistronic adenoviral vector-mediated gene delivery. Circulation. 109: 1415-20. PMID 15007006 DOI: 10.1161/01.Cir.0000121727.59564.5B  0.624
2004 Wu JC, Chen IY, Sundaresan G, Wang Y, Crystal RG, Gambhir SS. 805-1 Indirect imaging of vascular endothelial growth factor gene expression using a positron emission tomography reporter gene Journal of the American College of Cardiology. 43: A472. DOI: 10.1016/S0735-1097(04)91998-5  0.627
2003 Wu JC, Chen IY, Sundaresan G, Min JJ, De A, Qiao JH, Fishbein MC, Gambhir SS. Molecular imaging of cardiac cell transplantation in living animals using optical bioluminescence and positron emission tomography. Circulation. 108: 1302-5. PMID 12963637 DOI: 10.1161/01.Cir.0000091252.20010.6E  0.758
2003 Wu JC, Chen IY, De A, Min J, Sundaresan G, Qiao J, Fishbein MC, Gambhir SS. Positron emission tomography imaging of cellular cardiomyoplasty Journal of the American College of Cardiology. 41: 446. DOI: 10.1016/S0735-1097(03)81358-X  0.688
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