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Robert J. Gillies - Publications

Affiliations: 
1982-1988 Biochemistry Colorado State University, Fort Collins, CO 
 1988-2008 Biochemistry University of Arizona, Tucson, AZ 
 2008-2022 Cancer Physiology H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, United States 
Area:
cancer, imaging, physiology, evolution
Website:
https://moffitt.org/endeavor/archive/moffitt-mourns-the-loss-of-a-research-giant/
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Year Citation  Score
2023 Jardim-Perassi BV, Irrera P, Abrahams D, Estrella VC, Ordway B, Byrne SR, Ojeda AA, Whelan CJ, Kim J, Beatty MS, Damgaci-Erturk S, Longo DL, Gaspar KJ, Siegers GM, Centeno BA, ... ... Gillies RJ, et al. L-DOS47 enhances response to immunotherapy in pancreatic cancer tumor. Biorxiv : the Preprint Server For Biology. PMID 37693389 DOI: 10.1101/2023.08.28.555194  0.796
2022 Gillies RJ, Ibrahim-Hashim A, Ordway B, Gatenby RA. Back to basic: Trials and tribulations of alkalizing agents in cancer. Frontiers in Oncology. 12: 981718. PMID 36452492 DOI: 10.3389/fonc.2022.981718  0.811
2022 Rentzeperis F, Miller N, Ibrahim-Hashim A, Gillies RJ, Gatenby RA, Wallace D. A simulation of parental and glycolytic tumor phenotype competition predicts observed responses to pH changes and increased glycolysis after anti-VEGF therapy. Mathematical Biosciences. 352: 108909. PMID 36108797 DOI: 10.1016/j.mbs.2022.108909  0.304
2022 Russell S, Xu L, Kam Y, Abrahams D, Ordway B, Lopez AS, Bui MM, Johnson J, Epstein T, Ruiz E, Lloyd MC, Swietach P, Verduzco D, Wojtkowiak J, Gillies RJ. Proton export upregulates aerobic glycolysis. Bmc Biology. 20: 163. PMID 35840963 DOI: 10.1186/s12915-022-01340-0  0.784
2022 Jiang Q, Sudalagunta P, Silva MC, Canevarolo RR, Zhao X, Ahmed KT, Alugubelli RR, DeAvila G, Tungesvik A, Perez L, Gatenby R, Gillies R, Baz R, Meads MB, Shain KH, et al. CancerCellTracker: A Brightfield Time-lapse Microscopy Framework for Cancer Drug Sensitivity Estimation. Bioinformatics (Oxford, England). PMID 35751591 DOI: 10.1093/bioinformatics/btac417  0.367
2022 Mu W, Schabath MB, Gillies RJ. Images Are Data: Challenges and Opportunities in the Clinical Translation of Radiomics. Cancer Research. 82: 2066-2068. PMID 35661199 DOI: 10.1158/0008-5472.CAN-22-1183  0.316
2022 Pillai S, Mahmud I, Mahar R, Griffith C, Langsen M, Nguyen J, Wojtkowiak JW, Swietach P, Gatenby RA, Bui MM, Merritt ME, McDonald P, Garrett TJ, Gillies RJ. Lipogenesis mediated by OGR1 regulates metabolic adaptation to acid stress in cancer cells via autophagy. Cell Reports. 39: 110796. PMID 35545051 DOI: 10.1016/j.celrep.2022.110796  0.358
2022 Pérez-Morales J, Lu H, Mu W, Tunali I, Kutuk T, Eschrich SA, Balagurunathan Y, Gillies RJ, Schabath MB. Volume doubling time and radiomic features predict tumor behavior of screen-detected lung cancers. Cancer Biomarkers : Section a of Disease Markers. 33: 489-501. PMID 35491768 DOI: 10.3233/CBM-210194  0.345
2022 Tomaszewski MR, Fan S, Garcia A, Qi J, Kim Y, Gatenby RA, Schabath MB, Tap WD, Reinke DK, Makanji RJ, Reed DR, Gillies RJ. AI-Radiomics Can Improve Inclusion Criteria and Clinical Trial Performance. Tomography (Ann Arbor, Mich.). 8: 341-355. PMID 35202193 DOI: 10.3390/tomography8010028  0.288
2021 Tomaszewski MR, Latifi K, Boyer E, Palm RF, El Naqa I, Moros EG, Hoffe SE, Rosenberg SA, Frakes JM, Gillies RJ. Delta radiomics analysis of Magnetic Resonance guided radiotherapy imaging data can enable treatment response prediction in pancreatic cancer. Radiation Oncology (London, England). 16: 237. PMID 34911546 DOI: 10.1186/s13014-021-01957-5  0.336
2021 Pfaehler E, Zhovannik I, Wei L, Boellaard R, Dekker A, Monshouwer R, El Naqa I, Bussink J, Gillies R, Wee L, Traverso A. A systematic review and quality of reporting checklist for repeatability and reproducibility of radiomic features. Physics and Imaging in Radiation Oncology. 20: 69-75. PMID 34816024 DOI: 10.1016/j.phro.2021.10.007  0.296
2021 Tunali I, Tan Y, Gray JE, Katsoulakis E, Eschrich SA, Saller J, Aerts HJWL, Boyle T, Qi J, Guvenis A, Gillies RJ, Schabath MB. Hypoxia-Related Radiomics and Immunotherapy Response: A Multicohort Study of Non-Small Cell Lung Cancer. Jnci Cancer Spectrum. 5: pkab048. PMID 34409252 DOI: 10.1093/jncics/pkab048  0.327
2021 El-Kenawi A, Dominguez-Viqueira W, Liu M, Awasthi S, Abraham-Miranda J, Keske A, Steiner KK, Noel L, Serna AN, Dhillon J, Gillies RJ, Yu X, Koomen JM, Yamoah K, Gatenby RA, et al. Macrophage-derived cholesterol contributes to therapeutic resistance in prostate cancer. Cancer Research. PMID 34301759 DOI: 10.1158/0008-5472.CAN-20-4028  0.335
2021 Mu W, Jiang L, Shi Y, Tunali I, Gray JE, Katsoulakis E, Tian J, Gillies RJ, Schabath MB. Non-invasive measurement of PD-L1 status and prediction of immunotherapy response using deep learning of PET/CT images. Journal For Immunotherapy of Cancer. 9. PMID 34135101 DOI: 10.1136/jitc-2020-002118  0.302
2021 Ordway B, Gillies RJ, Damaghi M. Extracellular Acidification Induces Lysosomal Dysregulation. Cells. 10. PMID 34067971 DOI: 10.3390/cells10051188  0.801
2021 Jardim-Perassi BV, Mu W, Huang S, Tomaszewski MR, Poleszczuk J, Abdalah MA, Budzevich MM, Dominguez-Viqueira W, Reed DR, Bui MM, Johnson JO, Martinez GV, Gillies RJ. Deep-learning and MR images to target hypoxic habitats with evofosfamide in preclinical models of sarcoma. Theranostics. 11: 5313-5329. PMID 33859749 DOI: 10.7150/thno.56595  0.348
2021 Mu W, Katsoulakis E, Whelan CJ, Gage KL, Schabath MB, Gillies RJ. Radiomics predicts risk of cachexia in advanced NSCLC patients treated with immune checkpoint inhibitors. British Journal of Cancer. PMID 33828255 DOI: 10.1038/s41416-021-01375-0  0.317
2021 Grove O, Berglund AE, Schabath MB, Aerts HJWL, Dekker A, Wang H, Velazquez ER, Lambin P, Gu Y, Balagurunathan Y, Eikman E, Gatenby RA, Eschrich S, Gillies RJ. Correction: Quantitative Computed Tomographic Descriptors Associate Tumor Shape Complexity and Intratumor Heterogeneity with Prognosis in Lung Adenocarcinoma. Plos One. 16: e0248541. PMID 33684181 DOI: 10.1371/journal.pone.0248541  0.3
2021 Freischel AR, Damaghi M, Cunningham JJ, Ibrahim-Hashim A, Gillies RJ, Gatenby RA, Brown JS. Frequency-dependent interactions determine outcome of competition between two breast cancer cell lines. Scientific Reports. 11: 4908. PMID 33649456 DOI: 10.1038/s41598-021-84406-3  0.377
2021 Damaghi M, West J, Robertson-Tessi M, Xu L, Ferrall-Fairbanks MC, Stewart PA, Persi E, Fridley BL, Altrock PM, Gatenby RA, Sims PA, Anderson ARA, Gillies RJ. The harsh microenvironment in early breast cancer selects for a Warburg phenotype. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33452133 DOI: 10.1073/pnas.2011342118  0.353
2021 Tunali I, Gillies RJ, Schabath MB. Application of Radiomics and Artificial Intelligence for Lung Cancer Precision Medicine. Cold Spring Harbor Perspectives in Medicine. PMID 33431509 DOI: 10.1101/cshperspect.a039537  0.347
2021 Tomaszewski MR, Gillies RJ. The Biological Meaning of Radiomic Features. Radiology. 202553. PMID 33399513 DOI: 10.1148/radiol.2021202553  0.294
2021 Perez-Morales J, Tunali I, Lu H, Mu W, Balagurunathan Y, Gillies R, Schabath M. OA05.09 Volume Doubling Time and Radiomic Features Predict Tumor Behavior of Screen-Detected Lung Cancers in the National Lung Screening Trial (NLST) Journal of Thoracic Oncology. 16: S7. DOI: 10.1016/J.JTHO.2020.10.032  0.312
2020 Mu W, Liang Y, Hall LO, Tan Y, Balagurunathan Y, Wenham R, Wu N, Tian J, Gillies RJ. F-FDG PET/CT Habitat Radiomics Predicts Outcome of Patients with Cervical Cancer Treated with Chemoradiotherapy. Radiology. Artificial Intelligence. 2: e190218. PMID 33937845 DOI: 10.1148/ryai.2020190218  0.268
2020 Mu W, Tunali I, Qi J, Schabath MB, Gillies RJ. Radiomics of F Fluorodeoxyglucose PET/CT Images Predicts Severe Immune-related Adverse Events in Patients with NSCLC. Radiology. Artificial Intelligence. 2: e190063. PMID 33937811 DOI: 10.1148/ryai.2019190063  0.278
2020 Ordway B, Tomaszewski M, Byrne S, Abrahams D, Swietach P, Gillies RJ, Damaghi M. Targeting of Evolutionarily Acquired Cancer Cell Phenotype by Exploiting pHi-Metabolic Vulnerabilities. Cancers. 13. PMID 33379345 DOI: 10.3390/cancers13010064  0.813
2020 Tomaszewski MR, Dominguez-Viqueira W, Ortiz A, Shi Y, Costello JR, Enderling H, Rosenberg SA, Gillies RJ. Heterogeneity analysis of MRI T2 maps for measurement of early tumor response to radiotherapy. Nmr in Biomedicine. e4454. PMID 33325086 DOI: 10.1002/nbm.4454  0.372
2020 Persi E, Wolf YI, Horn D, Ruppin E, Demichelis F, Gatenby RA, Gillies RJ, Koonin EV. Publisher Correction: Mutation-selection balance and compensatory mechanisms in tumour evolution. Nature Reviews. Genetics. PMID 33318707 DOI: 10.1038/s41576-020-00313-9  0.211
2020 Damaghi M, Mori H, Byrne S, Xu L, Chen T, Johnson J, Gallant ND, Marusyk A, Borowsky AD, Gillies RJ. Collagen production and niche engineering: A novel strategy for cancer cells to survive acidosis in DCIS and evolve. Evolutionary Applications. 13: 2689-2703. PMID 33294017 DOI: 10.1111/Eva.13075  0.394
2020 Persi E, Wolf YI, Horn D, Ruppin E, Demichelis F, Gatenby RA, Gillies RJ, Koonin EV. Mutation-selection balance and compensatory mechanisms in tumour evolution. Nature Reviews. Genetics. PMID 33257848 DOI: 10.1038/s41576-020-00299-4  0.303
2020 Mu W, Jiang L, Zhang J, Shi Y, Gray JE, Tunali I, Gao C, Sun Y, Tian J, Zhao X, Sun X, Gillies RJ, Schabath MB. Non-invasive decision support for NSCLC treatment using PET/CT radiomics. Nature Communications. 11: 5228. PMID 33067442 DOI: 10.1038/s41467-020-19116-x  0.278
2020 Ibrahim-Hashim A, Luddy K, Abrahams D, Enriquez-Navas P, Damgaci S, Yao J, Chen T, Bui MM, Gillies RJ, O'Farrelly C, Richards CL, Brown JS, Gatenby RA. Artificial selection for host resistance to tumour growth and subsequent cancer cell adaptations: an evolutionary arms race. British Journal of Cancer. PMID 33024265 DOI: 10.1038/s41416-020-01110-1  0.314
2020 Gillies RJ, Schabath MB. Radiomics Improves Cancer Screening and Early Detection. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 32917666 DOI: 10.1158/1055-9965.EPI-20-0075  0.448
2020 Niell BL, Abdalah M, Stringfield O, Raghunand N, Ataya D, Gillies R, Balagurunathan Y. Quantitative measures of background parenchymal enhancement predict breast cancer risk. Ajr. American Journal of Roentgenology. PMID 32876474 DOI: 10.2214/Ajr.20.23804  0.313
2020 Wu H, Estrella V, Beatty M, Abrahams D, El-Kenawi A, Russell S, Ibrahim-Hashim A, Longo DL, Reshetnyak YK, Moshnikova A, Andreev OA, Luddy K, Damaghi M, Kodumudi K, Pillai SR, ... ... Gillies RJ, et al. T-cells produce acidic niches in lymph nodes to suppress their own effector functions. Nature Communications. 11: 4113. PMID 32807791 DOI: 10.1038/S41467-020-17756-7  0.326
2020 Paul R, Schabath M, Gillies R, Hall L, Goldgof D. Convolutional Neural Network ensembles for accurate lung nodule malignancy prediction 2 years in the future. Computers in Biology and Medicine. 122: 103882. PMID 32658721 DOI: 10.1016/J.Compbiomed.2020.103882  0.308
2020 Pérez-Morales J, Tunali I, Stringfield O, Eschrich SA, Balagurunathan Y, Gillies RJ, Schabath MB. Peritumoral and intratumoral radiomic features predict survival outcomes among patients diagnosed in lung cancer screening. Scientific Reports. 10: 10528. PMID 32601340 DOI: 10.1038/S41598-020-67378-8  0.405
2020 Paul R, Shafiq-Ul Hassan M, Moros EG, Gillies RJ, Hall LO, Goldgof DB. Deep Feature Stability Analysis Using CT Images of a Physical Phantom Across Scanner Manufacturers, Cartridges, Pixel Sizes, and Slice Thickness. Tomography (Ann Arbor, Mich.). 6: 250-260. PMID 32548303 DOI: 10.18383/j.tom.2020.00003  0.325
2020 Cherezov D, Paul R, Fetisov N, Gillies RJ, Schabath MB, Goldgof DB, Hall LO. Lung Nodule Sizes Are Encoded When Scaling CT Image for CNN's. Tomography (Ann Arbor, Mich.). 6: 209-215. PMID 32548298 DOI: 10.18383/j.tom.2019.00024  0.295
2020 Smith BJ, Buatti JM, Bauer C, Ulrich EJ, Ahmadvand P, Budzevich MM, Gillies RJ, Goldgof D, Grkovski M, Hamarneh G, Kinahan PE, Muzi JP, Muzi M, Laymon CM, Mountz JM, et al. Multisite Technical and Clinical Performance Evaluation of Quantitative Imaging Biomarkers from 3D FDG PET Segmentations of Head and Neck Cancer Images. Tomography (Ann Arbor, Mich.). 6: 65-76. PMID 32548282 DOI: 10.18383/j.tom.2020.00004  0.34
2020 Lu H, Parra NA, Qi J, Gage K, Li Q, Fan S, Feuerlein S, Pow-Sang J, Gillies R, Choi JW, Balagurunathan Y. Repeatability of Quantitative Imaging Features in Prostate Magnetic Resonance Imaging. Frontiers in Oncology. 10: 551. PMID 32457827 DOI: 10.3389/Fonc.2020.00551  0.329
2020 Ordway B, Swietach P, Gillies RJ, Damaghi M. Causes and Consequences of Variable Tumor Cell Metabolism on Heritable Modifications and Tumor Evolution. Frontiers in Oncology. 10: 373. PMID 32292719 DOI: 10.3389/fonc.2020.00373  0.803
2020 Paul R, Schabath MB, Gillies R, Hall LO, Goldgof DB. Hybrid models for lung nodule malignancy prediction utilizing convolutional neural network ensembles and clinical data. Journal of Medical Imaging (Bellingham, Wash.). 7: 024502. PMID 32280729 DOI: 10.1117/1.Jmi.7.2.024502  0.3
2020 Sudalagunta P, Silva MC, Canevarolo RR, Alugubelli RR, DeAvila G, Tungesvik A, Perez L, Gatenby R, Gillies R, Baz R, Meads MB, Shain KH, Silva AS. A pharmacodynamic model of clinical synergy in multiple myeloma. Ebiomedicine. 54: 102716. PMID 32268267 DOI: 10.1016/j.ebiom.2020.102716  0.358
2020 Zwanenburg A, Vallières M, Abdalah MA, Aerts HJWL, Andrearczyk V, Apte A, Ashrafinia S, Bakas S, Beukinga RJ, Boellaard R, Bogowicz M, Boldrini L, Buvat I, Cook GJR, Davatzikos C, ... ... Gillies RJ, et al. The Image Biomarker Standardization Initiative: Standardized Quantitative Radiomics for High-Throughput Image-based Phenotyping. Radiology. 191145. PMID 32154773 DOI: 10.1148/Radiol.2020191145  0.381
2020 Strobl MAR, Krause AL, Damaghi M, Gillies R, Anderson ARA, Maini PK. Mix and Match: Phenotypic Coexistence as a Key Facilitator of Cancer Invasion. Bulletin of Mathematical Biology. 82: 15. PMID 31953602 DOI: 10.1007/s11538-019-00675-0  0.331
2020 El-Kenawi A, Gatenbee C, Robertson-Tessi M, Bravo R, Dhillon J, Balagurunathan Y, Berglund A, Vishvakarma N, Ibrahim-Hashim A, Choi J, Luddy K, Gatenby R, Pilon-Thomas S, Anderson A, Ruffell B, ... Gillies R, et al. Correction: Acidity promotes tumour progression by altering macrophage phenotype in prostate cancer. British Journal of Cancer. PMID 31937927 DOI: 10.1038/S41416-019-0710-4  0.386
2020 Underwood P, Cameron M, Daly AC, Barnett T, Gwede C, Magliocco A, Centeno B, Chen D, Choi J, Jeong D, Gillies R, Malafa M, Judge A, Merchant N, Permuth J, et al. Abstract C091: Racial disparities in pancreatic cancer pancreatic cancer patients in Florida and an investigation into a possible role of cancer cachexia Cancer Epidemiology, Biomarkers & Prevention. DOI: 10.1158/1538-7755.Disp18-C091  0.309
2020 Mu W, Tunali I, Gray JE, Qi J, Schabath MB, Gillies RJ. Abstract 868: Prediction of clinical benefit to checkpoint blockade in advanced NSCLC patients using radiomics of PET/CT images Cancer Research. 80: 868-868. DOI: 10.1158/1538-7445.Am2020-868  0.304
2020 Tunali I, Tan Y, Gray JE, Katsoulakis E, Eschrich SA, Saller J, Boyle T, Qi J, Guvenis A, Gillies RJ, Schabath MB. Abstract 5806: Hypoxia-related radiomics predict checkpoint blockade immunotherapy response of non-small cell lung cancer patients Cancer Research. 80: 5806-5806. DOI: 10.1158/1538-7445.Am2020-5806  0.339
2020 Mukherjee P, Zhou M, Lee E, Schicht A, Balagurunathan Y, Napel S, Gillies R, Wong S, Thieme A, Leung A, Gevaert O. A shallow convolutional neural network predicts prognosis of lung cancer patients in multi-institutional computed tomography image datasets Nature Machine Intelligence. 2: 274-282. DOI: 10.1038/S42256-020-0173-6  0.336
2019 Tan Y, Mu W, Wang XC, Yang GQ, Gillies RJ, Zhang H. Whole-tumor radiomics analysis of DKI and DTI may improve the prediction of genotypes for astrocytomas: A preliminary study. European Journal of Radiology. 124: 108785. PMID 32004731 DOI: 10.1016/j.ejrad.2019.108785  0.423
2019 Mu W, Tunali I, Gray JE, Qi J, Schabath MB, Gillies RJ. Radiomics of F-FDG PET/CT images predicts clinical benefit of advanced NSCLC patients to checkpoint blockade immunotherapy. European Journal of Nuclear Medicine and Molecular Imaging. PMID 31807885 DOI: 10.1007/s00259-019-04625-9  0.389
2019 Li Q, Lu H, Choi J, Gage K, Feuerlein S, Pow-Sang JM, Gillies R, Balagurunathan Y. Radiological semantics discriminate clinically significant grade prostate cancer. Cancer Imaging : the Official Publication of the International Cancer Imaging Society. 19: 81. PMID 31796094 DOI: 10.1186/S40644-019-0272-Y  0.313
2019 Tan Y, Mu W, Wang XC, Yang GQ, Gillies RJ, Zhang H. Improving survival prediction of high-grade glioma via machine learning techniques based on MRI radiomic, genetic and clinical risk factors. European Journal of Radiology. 120: 108609. PMID 31606714 DOI: 10.1016/j.ejrad.2019.07.010  0.349
2019 Tunali I, Hall LO, Napel S, Cherezov D, Guvenis A, Gillies RJ, Schabath MB. Stability and reproducibility of computed tomography radiomic features extracted from peritumoral regions of lung cancer lesions. Medical Physics. PMID 31494946 DOI: 10.1002/Mp.13808  0.412
2019 El-Kenawi A, Gatenbee C, Robertson-Tessi M, Bravo R, Dhillon J, Balagurunathan Y, Berglund A, Visvakarma N, Ibrahim-Hashim A, Choi J, Luddy K, Gatenby R, Pilon-Thomas S, Anderson A, Ruffell B, ... Gillies R, et al. Acidity promotes tumour progression by altering macrophage phenotype in prostate cancer. British Journal of Cancer. PMID 31417189 DOI: 10.1038/S41416-019-0542-2  0.399
2019 Lu H, Mu W, Balagurunathan Y, Qi J, Abdalah MA, Garcia AL, Ye Z, Gillies RJ, Schabath MB. Multi-window CT based Radiomic signatures in differentiating indolent versus aggressive lung cancers in the National Lung Screening Trial: a retrospective study. Cancer Imaging : the Official Publication of the International Cancer Imaging Society. 19: 45. PMID 31253194 DOI: 10.1186/S40644-019-0232-6  0.427
2019 Balagurunathan Y, Schabath MB, Wang H, Liu Y, Gillies RJ. Quantitative Imaging features Improve Discrimination of Malignancy in Pulmonary nodules. Scientific Reports. 9: 8528. PMID 31189944 DOI: 10.1038/S41598-019-44562-Z  0.41
2019 Jardim-Perassi BV, Huang S, Dominguez-Viqueira W, Poleszczuk J, Budzevich MM, Abdalah MA, Pillai SR, Ruiz E, Bui MM, Zuccari DAPC, Gillies RJ, Martinez GV. Multiparametric MRI and co-registered histology identify tumor habitats in breast cancer mouse models. Cancer Research. PMID 31186232 DOI: 10.1158/0008-5472.CAN-19-0213  0.389
2019 Pastorekova S, Gillies RJ. The role of carbonic anhydrase IX in cancer development: links to hypoxia, acidosis, and beyond. Cancer Metastasis Reviews. PMID 31076951 DOI: 10.1007/s10555-019-09799-0  0.41
2019 Hormuth DA, Sorace AG, Virostko J, Abramson RG, Bhujwalla ZM, Enriquez-Navas P, Gillies R, Hazle JD, Mason RP, Quarles CC, Weis JA, Whisenant JG, Xu J, Yankeelov TE. Translating preclinical MRI methods to clinical oncology. Journal of Magnetic Resonance Imaging : Jmri. PMID 30925001 DOI: 10.1002/Jmri.26731  0.376
2019 Pillai SR, Damaghi M, Marunaka Y, Spugnini EP, Fais S, Gillies RJ. Causes, consequences, and therapy of tumors acidosis. Cancer Metastasis Reviews. PMID 30911978 DOI: 10.1007/s10555-019-09792-7  0.394
2019 Cherezov D, Goldgof D, Hall L, Gillies R, Schabath M, Müller H, Depeursinge A. Revealing Tumor Habitats from Texture Heterogeneity Analysis for Classification of Lung Cancer Malignancy and Aggressiveness. Scientific Reports. 9: 4500. PMID 30872600 DOI: 10.1038/S41598-019-38831-0  0.34
2019 Parra NA, Lu H, Choi J, Gage K, Pow-Sang J, Gillies RJ, Balagurunathan Y. Habitats in DCE-MRI to Predict Clinically Significant Prostate Cancers. Tomography (Ann Arbor, Mich.). 5: 68-76. PMID 30854444 DOI: 10.18383/j.tom.2018.00037  0.329
2019 Tunali I, Gray JE, Qi J, Abdalah M, Jeong DK, Guvenis A, Gillies RJ, Schabath MB. Novel clinical and radiomic predictors of rapid disease progression phenotypes among lung cancer patients treated with immunotherapy: An early report. Lung Cancer (Amsterdam, Netherlands). 129: 75-79. PMID 30797495 DOI: 10.1016/j.lungcan.2019.01.010  0.427
2019 Bi WL, Hosny A, Schabath MB, Giger ML, Birkbak NJ, Mehrtash A, Allison T, Arnaout O, Abbosh C, Dunn IF, Mak RH, Tamimi RM, Tempany CM, Swanton C, Hoffmann U, ... ... Gillies RJ, et al. Artificial intelligence in cancer imaging: Clinical challenges and applications. Ca: a Cancer Journal For Clinicians. PMID 30720861 DOI: 10.3322/Caac.21552  0.466
2019 Gillies RJ, Pilot C, Marunaka Y, Fais S. Targeting acidity in cancer and diabetes. Biochimica Et Biophysica Acta. Reviews On Cancer. PMID 30708040 DOI: 10.1016/j.bbcan.2019.01.003  0.341
2019 Pillai S, Langsen M, Nguyen J, Wojtkowiak J, Bui M, Gatenby R, Gillies R. Abstract 1846: Acid sensing G protein-coupled receptor OGR1 is required for acid induced adiposomogenesis in breast cancer cells Cancer Research. 79: 1846-1846. DOI: 10.1158/1538-7445.Sabcs18-1846  0.36
2019 Hashim AAI, Abrahams D, Luddy K, Gillies R, Richards CL, Brown J, Gatenby R. Abstract 3773: Investigating the tumor-host evolutionary arms race as a possible strategy for cancer therapy Cancer Research. 79: 3773-3773. DOI: 10.1158/1538-7445.Am2019-3773  0.404
2019 Antic S, Osterman T, Balar A, Lakhani D, Nguyen R, Block S, Fileds K, Winston B, Muterspaugh A, Huo Y, Gao R, Leader J, Wilson D, Nair V, Gillies R, et al. Abstract 3317: Development of a lung nodule cohort with integrated clinical, molecular and imaging biomarkers Cancer Research. 79: 3317-3317. DOI: 10.1158/1538-7445.Am2019-3317  0.34
2019 Schabath MB, Tunali I, Gray JE, Gillies RJ. Abstract 3301: Predictors of disease progression and treatment response among lung cancer patients treated with immunotherapy Cancer Research. 79: 3301-3301. DOI: 10.1158/1538-7445.Am2019-3301  0.339
2019 Estrella V, Swietach P, Luddy K, Abrahams D, Enriquez-Navas P, Reshetnyak Y, Damaghi M, Gillies RJ. Abstract 1140: A new twist on an old strategy: Can the lymph node environment help cancers escape immune surveillance Cancer Research. 79: 1140-1140. DOI: 10.1158/1538-7445.Am2019-1140  0.345
2019 Morales JP, Tunali I, Stringfield O, Eschrich S, Balagurunathan Y, Gillies R, Schabath M. OA02.08 Peritumoral and Intratumoral Radiomic Features Identify Aggressive Screen-Detected Early-Stage Lung Cancers Journal of Thoracic Oncology. 14. DOI: 10.1016/J.Jtho.2019.09.030  0.392
2019 Tunali I, Tan Y, Gray JE, Eschrich S, Guvenis A, Gillies R, Schabath M. OA02.05 Clinical-Radiomic Models Predict Overall Survival Among Non-Small Cell Lung Cancer Patients Treated with Immunotherapy Journal of Thoracic Oncology. 14. DOI: 10.1016/J.Jtho.2019.09.027  0.326
2018 Parra AN, Lu H, Li Q, Stoyanova R, Pollack A, Punnen S, Choi J, Abdalah M, Lopez C, Gage K, Park JY, Kosj Y, Pow-Sang JM, Gillies RJ, Balagurunathan Y. Predicting clinically significant prostate cancer using DCE-MRI habitat descriptors. Oncotarget. 9: 37125-37136. PMID 30647849 DOI: 10.18632/Oncotarget.26437  0.436
2018 Alahmari SS, Cherezov D, Goldgof D, Hall L, Gillies RJ, Schabath MB. Delta Radiomics Improves Pulmonary Nodule Malignancy Prediction in Lung Cancer Screening. Ieee Access : Practical Innovations, Open Solutions. 6: 77796-77806. PMID 30607311 DOI: 10.1109/Access.2018.2884126  0.426
2018 Cherezov D, Hawkins SH, Goldgof DB, Hall LO, Liu Y, Li Q, Balagurunathan Y, Gillies RJ, Schabath MB. Delta radiomic features improve prediction for lung cancer incidence: A nested case-control analysis of the National Lung Screening Trial. Cancer Medicine. PMID 30507033 DOI: 10.1002/Cam4.1852  0.397
2018 Hosny A, Parmar C, Coroller TP, Grossmann P, Zeleznik R, Kumar A, Bussink J, Gillies RJ, Mak RH, Aerts HJWL. Deep learning for lung cancer prognostication: A retrospective multi-cohort radiomics study. Plos Medicine. 15: e1002711. PMID 30500819 DOI: 10.1371/journal.pmed.1002711  0.436
2018 Napel S, Mu W, Jardim-Perassi BV, Aerts HJWL, Gillies RJ. Quantitative imaging of cancer in the postgenomic era: Radio(geno)mics, deep learning, and habitats. Cancer. PMID 30383900 DOI: 10.1002/Cncr.31630  0.485
2018 Traverso A, Wee L, Dekker A, Gillies R. Repeatability and Reproducibility of Radiomic Features: A Systematic Review. International Journal of Radiation Oncology, Biology, Physics. PMID 30170872 DOI: 10.1016/j.ijrobp.2018.05.053  0.412
2018 Kishimoto S, Oshima N, Krishna MC, Gillies RJ. Direct and indirect assessment of cancer metabolism explored by MRI. Nmr in Biomedicine. e3966. PMID 30169896 DOI: 10.1002/nbm.3966  0.45
2018 Persi E, Duran-Frigola M, Damaghi M, Roush WR, Aloy P, Cleveland JL, Gillies RJ, Ruppin E. Systems analysis of intracellular pH vulnerabilities for cancer therapy. Nature Communications. 9: 2997. PMID 30065243 DOI: 10.1038/S41467-018-05261-X  0.502
2018 Shafiq-Ul-Hassan M, Latifi K, Zhang G, Ullah G, Gillies R, Moros E. Voxel size and gray level normalization of CT radiomic features in lung cancer. Scientific Reports. 8: 10545. PMID 30002441 DOI: 10.1038/S41598-018-28895-9  0.465
2018 Gillies RJ, Brown JS, Anderson ARA, Gatenby RA. Eco-evolutionary causes and consequences of temporal changes in intratumoural blood flow. Nature Reviews. Cancer. PMID 29891961 DOI: 10.1038/S41568-018-0030-7  0.409
2018 Walton ZE, Patel CH, Brooks RC, Yu Y, Ibrahim-Hashim A, Riddle M, Porcu A, Jiang T, Ecker BL, Tameire F, Koumenis C, Weeraratna AT, Welsh DK, Gillies R, Alwine JC, et al. Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR. Cell. PMID 29861175 DOI: 10.1016/J.Cell.2018.05.009  0.314
2018 Matsumoto S, Kishimoto S, Saito K, Takakusagi Y, Munasinghe JP, Devasahayam N, Hart C, Gillies RJ, Mitchell JB, Krishna MC. Metabolic and physiologic imaging biomarkers of the tumor microenvironment predict treatment outcome with radiation or a hypoxia-activated prodrug in mice. Cancer Research. PMID 29792309 DOI: 10.1158/0008-5472.CAN-18-0491  0.303
2018 Gillies RJ, Balagurunathan Y. Perfusion MR Imaging of Breast Cancer: Insights Using "Habitat Imaging". Radiology. 180271. PMID 29714676 DOI: 10.1148/Radiol.2018180271  0.41
2018 Liu Y, Kim J, Balagurunathan Y, Hawkins S, Stringfield O, Schabath MB, Li Q, Qu F, Liu S, Garcia AL, Ye Z, Gillies RJ. Prediction of pathological nodal involvement by CT-based Radiomic features of the primary tumor in patients with clinically node-negative peripheral lung adenocarcinomas. Medical Physics. PMID 29624702 DOI: 10.1002/Mp.12901  0.407
2018 Paul R, Hawkins SH, Schabath MB, Gillies RJ, Hall LO, Goldgof DB. Predicting malignant nodules by fusing deep features with classical radiomics features. Journal of Medical Imaging (Bellingham, Wash.). 5: 011021. PMID 29594181 DOI: 10.1117/1.Jmi.5.1.011021  0.41
2018 Damgaci S, Ibrahim-Hashim A, Enriquez-Navas PM, Pilon-Thomas S, Guvenis A, Gillies RJ. Hypoxia and Acidosis: Immune Suppressors and Therapeutic Targets. Immunology. PMID 29485185 DOI: 10.1111/imm.12917  0.339
2018 Shafiq-Ul-Hassan M, Zhang GG, Hunt DC, Latifi K, Ullah G, Gillies RJ, Moros EG. Accounting for reconstruction kernel-induced variability in CT radiomic features using noise power spectra. Journal of Medical Imaging (Bellingham, Wash.). 5: 011013. PMID 29285518 DOI: 10.1117/1.Jmi.5.1.011013  0.355
2018 Pilot C, Mahipal A, Gillies RJ. Buffer Therapy â Buffer Diet Journal of Nutrition and Food Sciences. 8: 1-5. DOI: 10.4172/2155-9600.1000685  0.365
2018 Lu H, Mu W, Balagurunathan Y, Qi J, Schabath M, Gillies RJ. Abstract B10: Radiomics signatures on the region defined by using multi-window CT to improve detection lung cancer screening Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Aacriaslc18-B10  0.309
2018 Garcia L, Gillies RJ, Gatenby RA. Abstract A58: Application of evolutionary principles to control ER+ breast tumors Molecular Cancer Research. 16. DOI: 10.1158/1557-3125.Advbc17-A58  0.369
2018 Mu W, Qi J, Lu H, Schabath M, Balagurunathan Y, Tunali I, Pilon-Thomas S, Gillies RJ. Abstract 3634: PET/CT imaging prediction of response to checkpoint blockade in advanced non-small cell lung cancer patients Cancer Research. 78: 3634-3634. DOI: 10.1158/1538-7445.Am2018-3634  0.376
2018 Ji K, Zhao Z, Moin K, Xu Y, Gillies RJ, Mattingly RR, Sloane BF. Abstract 2131: Paracrine cytokine pathways mediate metastasis of breast cancer to lymphatics Cancer Research. 78: 2131-2131. DOI: 10.1158/1538-7445.Am2018-2131  0.359
2018 Niazi A, Joseph JJ, Gillies RJ, Damaghi M. Abstract 171: Acid-induced collagen remodeling promotes cancer progress as a result of niche engineering Cancer Research. 78: 171-171. DOI: 10.1158/1538-7445.Am2018-171  0.398
2018 Patiño AM, Junqueira MS, Zhang X, Bailey K, Ibrahim-Hashim A, Gillies RJ, Chammas R. Abstract A121: Transient increase of tumor perfusion using hypertonic saline Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-A121  0.346
2018 Traverso A, Wee L, Dekker A, Gillies R. EP-2132: Repeatability and reproducibility of radiomic features: results of a systematic review Radiotherapy and Oncology. 127. DOI: 10.1016/S0167-8140(18)32441-1  0.332
2017 Tunali I, Stringfield O, Guvenis A, Wang H, Liu Y, Balagurunathan Y, Lambin P, Gillies RJ, Schabath MB. Radial gradient and radial deviation radiomic features from pre-surgical CT scans are associated with survival among lung adenocarcinoma patients. Oncotarget. 8: 96013-96026. PMID 29221183 DOI: 10.18632/Oncotarget.21629  0.4
2017 Russell S, Wojtkowiak J, Neilson A, Gillies RJ. Metabolic Profiling of healthy and cancerous tissues in 2D and 3D. Scientific Reports. 7: 15285. PMID 29127321 DOI: 10.1038/s41598-017-15325-5  0.33
2017 Zhou M, Scott J, Chaudhury B, Hall L, Goldgof D, Yeom KW, Iv M, Ou Y, Kalpathy-Cramer J, Napel S, Gillies R, Gevaert O, Gatenby R. Radiomics in Brain Tumor: Image Assessment, Quantitative Feature Descriptors, and Machine-Learning Approaches. Ajnr. American Journal of Neuroradiology. PMID 28982791 DOI: 10.3174/Ajnr.A5391  0.412
2017 Li Q, Kim J, Balagurunathan Y, Qi J, Liu Y, Latifi K, Moros EG, Schabath MB, Ye Z, Gillies RJ, Dilling TJ. CT imaging features associated with recurrence in non-small cell lung cancer patients after stereotactic body radiotherapy. Radiation Oncology (London, England). 12: 158. PMID 28946909 DOI: 10.1186/S13014-017-0892-Y  0.43
2017 Pompo GD, Lemma S, Canti L, Rucci N, Ponzetti M, Errani C, Donati DM, Russell S, Gillies R, Chano T, Baldini N, Avnet S. Intratumoral acidosis fosters cancer-induced bone pain through the activation of the mesenchymal tumor-associated stroma in bone metastasis from breast carcinoma. Oncotarget. 8: 54478-54496. PMID 28903357 DOI: 10.18632/Oncotarget.17091  0.353
2017 Lemma S, Di Pompo G, Porporato PE, Sboarina M, Russell S, Gillies RJ, Baldini N, Sonveaux P, Avnet S. MDA-MB-231 breast cancer cells fuel osteoclast metabolism and activity: A new rationale for the pathogenesis of osteolytic bone metastases. Biochimica Et Biophysica Acta. PMID 28866133 DOI: 10.1016/j.bbadis.2017.08.030  0.362
2017 Chang YC, Ackerstaff E, Tschudi Y, Jimenez B, Foltz W, Fisher C, Lilge L, Cho H, Carlin S, Gillies RJ, Balagurunathan Y, Yechieli RL, Subhawong T, Turkbey B, Pollack A, et al. Delineation of Tumor Habitats based on Dynamic Contrast Enhanced MRI. Scientific Reports. 7: 9746. PMID 28851989 DOI: 10.1038/S41598-017-09932-5  0.479
2017 Grossmann P, Stringfield O, El-Hachem N, Bui MM, Rios Velazquez E, Parmar C, Leijenaar RT, Haibe-Kains B, Lambin P, Gillies R, Aerts HJ. Defining the biological basis of radiomic phenotypes in lung cancer. Elife. 6. PMID 28731408 DOI: 10.7554/Elife.23421  0.473
2017 Baldini N, De Milito A, Feron O, Gillies RJ, Michiels C, Otto AM, Pastoreková S, Pedersen SF, Porporato PE, Sonveaux P, Supuran CT, Avnet S. Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Networks in Cancer. Frontiers in Pharmacology. 8: 411. PMID 28725193 DOI: 10.3389/Fphar.2017.00411  0.346
2017 Yip SSF, Liu Y, Parmar C, Li Q, Liu S, Qu F, Ye Z, Gillies RJ, Aerts HJWL. Associations between radiologist-defined semantic and automatically computed radiomic features in non-small cell lung cancer. Scientific Reports. 7: 3519. PMID 28615677 DOI: 10.1038/s41598-017-02425-5  0.417
2017 Rios Velazquez E, Parmar C, Liu Y, Coroller TP, Cruz G, Stringfield O, Ye Z, Makrigiorgos GM, Fennessy FMM, Mak RH, Gillies RJ, Quackenbush J, Aerts H. Somatic mutations drive distinct imaging phenotypes in lung cancer. Cancer Research. PMID 28566328 DOI: 10.1158/0008-5472.Can-17-0122  0.345
2017 Ibrahim-Hashim A, Abrahams D, Enriquez-Navas PM, Luddy K, Gatenby RA, Gillies RJ. Tris-base buffer: a promising new inhibitor for cancer progression and metastasis. Cancer Medicine. PMID 28556628 DOI: 10.1002/cam4.1032  0.497
2017 Li Q, Kim J, Balagurunathan Y, Liu Y, Latifi K, Stringfield O, Garcia A, Moros EG, Dilling TJ, Schabath MB, Ye Z, Gillies RJ. Imaging features from pre-treatment CT scans are associated with clinical outcomes in non-small-cell lung cancer patients treated with stereotactic body radiotherapy. Medical Physics. PMID 28464316 DOI: 10.1002/Mp.12309  0.424
2017 Caudell JJ, Torres-Roca JF, Gillies RJ, Enderling H, Kim S, Rishi A, Moros EG, Harrison LB. The future of personalised radiotherapy for head and neck cancer. The Lancet. Oncology. PMID 28456586 DOI: 10.1016/S1470-2045(17)30252-8  0.396
2017 Silva AS, Silva MD, Sudalagunta P, Distler AI, Jacobson T, Collins A, Nguyen T, Song J, Chen DT, Chen L, Cubitt CL, Baz R, Perez L, Rebatchouk D, Dalton W, ... ... Gillies RJ, et al. An ex vivo platform for the prediction of clinical response in multiple myeloma. Cancer Research. PMID 28400475 DOI: 10.1158/0008-5472.Can-17-0502  0.301
2017 Ibrahim-Hashim A, Robertson-Tessi M, Enrizues-Navas P, Damaghi M, Balagurunathan Y, Wojtkowiak JW, Russell S, Yoonseok K, Lloyd MC, Bui MM, Brown JS, Anderson AR, Gillies RJ, Gatenby RA. Defining cancer subpopulations by adaptive strategies rather than molecular properties provides novel insights into intratumoral evolution. Cancer Research. PMID 28249898 DOI: 10.1158/0008-5472.Can-16-2844  0.496
2017 Beichel RR, Smith BJ, Bauer C, Ulrich EJ, Ahmadvand P, Budzevich MM, Gillies RJ, Goldgof D, Grkovski M, Hamarneh G, Huang Q, Kinahan PE, Laymon CM, Mountz JM, Muzi JP, et al. Multi-site quality and variability analysis of 3D FDG PET segmentations based on phantom and clinical image data. Medical Physics. 44: 479-496. PMID 28205306 DOI: 10.1002/Mp.12041  0.419
2017 Shafiq-Ul-Hassan M, Zhang GG, Latifi K, Ullah G, Hunt DC, Balagurunathan Y, Abdalah MA, Schabath MB, Goldgof DG, Mackin D, Court LE, Gillies RJ, Moros EG. Intrinsic dependencies of CT radiomic features on voxel size and number of gray levels. Medical Physics. PMID 28112418 DOI: 10.1002/Mp.12123  0.374
2017 Damaghi M, Gillies R. Phenotypic changes of acid-adapted cancer cells push them toward aggressiveness in their evolution in the tumor microenvironment. Cell Cycle. 16: 1739-1743. PMID 27635863 DOI: 10.1080/15384101.2016.1231284  0.434
2017 Luddy KA, Poleszczuk J, Hashim AI, Damaghi M, Gillies R, Brown J, Gatenby R. Abstract B51: Tumor cell evolutionary strategies to overcome immune response Cancer Research. 77. DOI: 10.1158/1538-7445.Epso16-B51  0.361
2017 Jardim-Perassi BV, Dominguez-Viqueira W, El-Kenawi A, Abrahams DF, Budzevich M, Ruiz E, Huang S, Enriquez-Navas PM, Martinez G, Zuccari DAPdC, Gillies RJ. Abstract 884: Detection of intratumoral heterogeneity using MR-defined tumor habitats in breast cancer model under melatonin treatment Cancer Research. 77: 884-884. DOI: 10.1158/1538-7445.Am2017-884  0.351
2017 Hashim AAI, Abrahams D, Xu L, Centeno B, Sunassee E, Abddelgader R, Dubois L, Lambin P, Gatenby RA, Gillies RJ. Abstract 5932: Targeting tumor acidity with the LDHA inhibitor (FX11) and CAIX inhibitor (DH348) overcomes resistance to PD-1 blockade and inhibits metastasis in a pancreatic cancer model Cancer Research. 77: 5932-5932. DOI: 10.1158/1538-7445.Am2017-5932  0.32
2017 Pillai S, Wojtkowiak JW, Damaghi M, Gatenby R, Gillies R. Abstract 3538: Enhanced dependence on lipid metabolism is a cellular adaptation to acidic microenvironment Cancer Research. 77: 3538-3538. DOI: 10.1158/1538-7445.Am2017-3538  0.371
2017 Abrahams D, Hashim AI, Luddy K, Gillies R, Gatenby R, Brown J. Abstract 2929: Exploratory evolved strategies that limit cancer growth for possible new therapeutic strategies Cancer Research. 77: 2929-2929. DOI: 10.1158/1538-7445.Am2017-2929  0.3
2017 Tunali I, Gray J, Abdullah M, Qi J, Balagurunathan Y, Guvenis A, Gillies R, Schabath M. PUB063 Epidemiologic and Radiomic Analysis of Hyperprogressers of Lung Cancer Patients Treated with Immunotherapy Journal of Thoracic Oncology. 12. DOI: 10.1016/J.Jtho.2017.09.1926  0.399
2017 Cherezov D, Hawkins S, Goldgof D, Hall L, Balagurunathan Y, Gillies R, Schabath M. P1.03-063 Quantitative Imaging Features Predict Incidence Lung Cancer in Low-Dose Computed Tomography (LDCT) Screening Journal of Thoracic Oncology. 12: S582. DOI: 10.1016/J.Jtho.2016.11.735  0.316
2017 Tunali I, Gray J, Qi J, Abdullah M, Balagurunathan Y, Gillies R, Schabath M. P1.01-041 Quantitative Imaging Features Predict Response of Immunotherapy in Non-Small Cell Lung Cancer Patients: Topic: Prognostic Factors, Treatment Journal of Thoracic Oncology. 12. DOI: 10.1016/J.Jtho.2016.11.565  0.349
2017 Shafiq-ul-hassan M, Zhang GG, Latifi K, Hunt DC, Gillies RJ, Moros EG. Validation of Voxel-Size Normalization of CT Radiomic Features in Lung Cancer Patients International Journal of Radiation Oncology Biology Physics. 99. DOI: 10.1016/J.Ijrobp.2017.06.2337  0.404
2017 Grass G, Latifi K, Oliver D, Bello C, Forsyth P, Carney G, Gillies R, Stringfield O, Robinson T. Radiomics-Based Characterization of Recurrence Risk in Primary CNS Lymphoma International Journal of Radiation Oncology*Biology*Physics. 99: E591. DOI: 10.1016/J.Ijrobp.2017.06.2024  0.316
2016 Stoyanova R, Takhar M, Tschudi Y, Ford JC, Solórzano G, Erho N, Balagurunathan Y, Punnen S, Davicioni E, Gillies RJ, Pollack A. Prostate cancer radiomics and the promise of radiogenomics. Translational Cancer Research. 5: 432-447. PMID 29188191 DOI: 10.21037/Tcr.2016.06.20  0.428
2016 Kalpathy-Cramer J, Mamomov A, Zhao B, Lu L, Cherezov D, Napel S, Echegaray S, Rubin D, McNitt-Gray M, Lo P, Sieren JC, Uthoff J, Dilger SK, Driscoll B, Yeung I, ... ... Gillies R, et al. Radiomics of Lung Nodules: A Multi-Institutional Study of Robustness and Agreement of Quantitative Imaging Features. Tomography : a Journal For Imaging Research. 2: 430-437. PMID 28149958 DOI: 10.18383/j.tom.2016.00235  0.289
2016 Shafiq Ul Hassan M, Budzevich M, Zhang G, Latifi K, Hunt D, Gillies R, Moros E. SU-F-R-30: Interscanner Variability of Radiomics Features in Computed Tomography (CT) Using a Standard ACR Phantom. Medical Physics. 43: 3379. PMID 28048783 DOI: 10.1118/1.4955802  0.337
2016 Shafiq Ul Hassan M, Zhang G, Latifi K, Oliver J, Hunt D, Guzman R, Balagurunathan Y, Mackin D, Court L, Gillies R, Moros E. MO-DE-207B-04: Impact of Reconstruction Field of View On Radiomics Features in Computed Tomography (CT) Using a Texture Phantom. Medical Physics. 43: 3705. PMID 28046757 DOI: 10.1118/1.4957253  0.333
2016 Avnet S, Di Pompo G, Chano T, Errani C, Ibrahim-Hashim A, Gillies RJ, Donati DM, Baldini N. Cancer-associated mesenchymal stroma fosters the stemness of osteosarcoma cells in response to intratumoral acidosis via NF-κB acivation. International Journal of Cancer. PMID 27888521 DOI: 10.1002/ijc.30540  0.318
2016 Gillies RJ, Beyer T. PET and MRI: Is the Whole Greater than the Sum of Its Parts? Cancer Research. PMID 27729326 DOI: 10.1158/0008-5472.CAN-16-2121  0.455
2016 O'Connor JP, Aboagye EO, Adams JE, Aerts HJ, Barrington SF, Beer AJ, Boellaard R, Bohndiek SE, Brady M, Brown G, Buckley DL, Chenevert TL, Clarke LP, Collette S, Cook GJ, ... ... Gillies RJ, et al. Imaging biomarker roadmap for cancer studies. Nature Reviews. Clinical Oncology. PMID 27725679 DOI: 10.1038/Nrclinonc.2016.162  0.324
2016 Zhou M, Chaudhury B, Hall LO, Goldgof DB, Gillies RJ, Gatenby RA. Identifying spatial imaging biomarkers of glioblastoma multiforme for survival group prediction. Journal of Magnetic Resonance Imaging : Jmri. PMID 27678245 DOI: 10.1002/Jmri.25497  0.435
2016 Liu Y, Balagurunathan Y, Atwater T, Antic S, Li Q, Walker RC, Smith G, Massion PP, Schabath MB, Gillies RJ. Radiological Image traits Predictive of Cancer Status in Pulmonary Nodules. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27663588 DOI: 10.1158/1078-0432.Ccr-15-3102  0.311
2016 Permuth JB, Choi J, Balarunathan Y, Kim J, Chen DT, Chen L, Orcutt S, Doepker MP, Gage K, Zhang G, Latifi K, Hoffe S, Jiang K, Coppola D, Centeno BA, ... ... Gillies R, et al. Combining radiomic features with a miRNA classifier may improve prediction of malignant pathology for pancreatic intraductal papillary mucinous neoplasms. Oncotarget. PMID 27589689 DOI: 10.18632/Oncotarget.11768  0.393
2016 Schabath MB, Massion PP, Thompson ZJ, Eschrich SA, Balagurunathan Y, Goldof D, Aberle DR, Gillies RJ. Differences in Patient Outcomes of Prevalence, Interval, and Screen-Detected Lung Cancers in the CT Arm of the National Lung Screening Trial. Plos One. 11: e0159880. PMID 27509046 DOI: 10.1371/Journal.Pone.0159880  0.316
2016 Stoyanova R, Pollack A, Takhar M, Lynne C, Parra N, Lam LL, Alshalalfa M, Buerki C, Castillo R, Jorda M, Ashab HA, Kryvenko ON, Punnen S, Parekh DJ, Abramowitz MC, ... Gillies RJ, et al. Association of multiparametric MRI quantitative imaging features with prostate cancer gene expression in MRI-targeted prostate biopsies. Oncotarget. PMID 27438142 DOI: 10.18632/Oncotarget.10523  0.406
2016 Hawkins S, Wang H, Liu Y, Garcia A, Stringfield O, Krewer H, Li Q, Cherezov D, Gatenby RA, Balagurunathan Y, Goldgof D, Schabath MB, Hall L, Gillies RJ. Predicting malignant nodules from screening CTs. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 27422797 DOI: 10.1016/J.Jtho.2016.07.002  0.411
2016 Zhang X, Wojtkowiak JW, Martinez GV, Cornnell HH, Hart CP, Baker AF, Gillies R. MR Imaging Biomarkers to Monitor Early Response to Hypoxia-Activated Prodrug TH-302 in Pancreatic Cancer Xenografts. Plos One. 11: e0155289. PMID 27227903 DOI: 10.1371/Journal.Pone.0155289  0.385
2016 Liu Y, Kim J, Balagurunathan Y, Li Q, Garcia AL, Stringfield O, Ye Z, Gillies RJ. Radiomic Features Are Associated With EGFR Mutation Status in Lung Adenocarcinomas. Clinical Lung Cancer. PMID 27017476 DOI: 10.1016/J.Cllc.2016.02.001  0.36
2016 Lloyd MC, Cunningham JJ, Bui MM, Gillies RJ, Brown JS, Gatenby RA. Darwinian dynamics of intratumoral heterogeneity: not solely random mutations but also variable environmental selection forces. Cancer Research. PMID 27009166 DOI: 10.1158/0008-5472.Can-15-2962  0.502
2016 Enriquez-Navas PM, Kam Y, Das T, Hassan S, Silva A, Foroutan P, Ruiz E, Martinez G, Minton S, Gillies RJ, Gatenby RA. Exploiting evolutionary principles to prolong tumor control in preclinical models of breast cancer. Science Translational Medicine. 8: 327ra24. PMID 26912903 DOI: 10.1126/scitranslmed.aad7842  0.489
2016 Kalpathy-Cramer J, Zhao B, Goldgof D, Gu Y, Wang X, Yang H, Tan Y, Gillies R, Napel S. A Comparison of Lung Nodule Segmentation Algorithms: Methods and Results from a Multi-institutional Study. Journal of Digital Imaging. PMID 26847203 DOI: 10.1007/S10278-016-9859-Z  0.301
2016 Yankeelov TE, Mankoff DA, Schwartz LH, Lieberman FS, Buatti JM, Mountz JM, Erickson BJ, Fennessy FM, Huang W, Kalpathy-Cramer J, Wahl RL, Linden HM, Kinahan PE, Zhao B, Hylton NM, ... Gillies RJ, et al. Quantitative Imaging in Cancer Clinical Trials. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 22: 284-90. PMID 26773162 DOI: 10.1158/1078-0432.Ccr-14-3336  0.333
2016 Permuth JB, Choi J, Balarunathan Y, Kim J, Chen D, Jiang K, Orcutt S, Chen L, Quinn K, Carvajal R, Gonzalez-Calderon G, Fournier M, Abdalla M, Garcia A, Bouton A, ... ... Gillies R, et al. Abstract 970A: Using a radiogenomic approach to classify pancreatic cancer precursors Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-970A  0.342
2016 El-Kenawi A, Ibrahim-Hashim A, Luddy K, Ruffell B, Pilon-Thomas S, Gatenby R, Gillies R. Abstract 5101: Tumor-secreted acids alter macrophage phenotype Cancer Research. 76: 5101-5101. DOI: 10.1158/1538-7445.Am2016-5101  0.324
2016 Damaghi M, Chen T, Johnson J, Gillies RJ. Abstract 5094: Acid-induced collagen remodeling promotes cancer progress as a result of niche engineering competition between cancer and stroma cells Cancer Research. 76: 5094-5094. DOI: 10.1158/1538-7445.Am2016-5094  0.344
2016 Velazquez ER, Liu Y, Parmar C, Narayan V, Gillies R, Aerts H. MO‐DE‐207B‐08: Radiomic CT Features Complement Semantic Annotations to Predict EGFR Mutations in Lung Adenocarcinomas Medical Physics. 43: 3706-3706. DOI: 10.1118/1.4957257  0.403
2016 Geiger B, Hawkins SH, Hall LO, Goldgof DB, Balagurunathan Y, Gatenby RA, Gillies RJ. Change descriptors for determining nodule malignancy in national lung screening trial CT screening images Proceedings of Spie. 9785: 978535. DOI: 10.1117/12.2217444  0.417
2016 Farhidzadeh H, Chaudhury B, Scott JG, Goldgof DB, Hall LO, Gatenby RA, Gillies RJ, Raghavan M. Signal intensity analysis of ecological defined habitat in soft tissue sarcomas to predict metastasis development Progress in Biomedical Optics and Imaging - Proceedings of Spie. 9785. DOI: 10.1117/12.2216961  0.458
2016 Li Q, Balagurunathan Y, Liu Y, Schabath MB, Gillies RJ. Performance comparison of quantitative semantic features and lung-RADS in the National Lung Screening Trial Proceedings of Spie. 9787. DOI: 10.1117/12.2216948  0.32
2016 Liu Y, Balagurunathan Y, Atwater T, Antic S, Li Q, Walker R, Smith GT, Massion PP, Schabath MB, Gillies RJ. Quantitative imaging features to predict cancer status in lung nodules Proceedings of Spie. 9787. DOI: 10.1117/12.2216809  0.33
2016 Chaudhury B, Zhou M, Farhidzadeh H, Goldgof DB, Hall LO, Gatenby RA, Gillies RJ, Weinfurtner RJ, Drukteinis JS. Predicting Ki67% expression from DCE-MR images of breast tumors using textural kinetic features in tumor habitats Proceedings of Spie. 9785. DOI: 10.1117/12.2216075  0.431
2016 Farhidzadeh H, Goldgof DB, Hall LO, Gatenby RA, Gillies RJ, Raghavan M. Texture Feature Analysis to Predict Metastatic and Necrotic Soft Tissue Sarcomas Proceedings - 2015 Ieee International Conference On Systems, Man, and Cybernetics, Smc 2015. 2798-2802. DOI: 10.1109/SMC.2015.488  0.356
2016 Schabath MB, Liu Y, Wang H, Stringfield O, Balagurunathan Y, Garcia A, Hall L, Goldgof D, Gillies RJ. Diagnostic and predictive quantitative-imaging features in lung cancer screening Journal of Thoracic Oncology. 11: S41-S42. DOI: 10.1016/J.Jtho.2015.12.070  0.327
2016 Schabath M, Balagurunathan Y, Dmitry G, LAwrence H, Samuel H, Stringfield O, Li Q, Liu Y, Gillies R. Radiomics of lung cancer Journal of Thoracic Oncology. 11: S5-S6. DOI: 10.1016/J.Jtho.2015.12.008  0.387
2015 Pilon-Thomas S, Kodumudi KN, El-Kenawi AE, Russell S, Weber AM, Luddy K, Damaghi M, Wojtkowiak JW, Mulé JJ, Ibrahim-Hashim A, Gillies RJ. Neutralization of tumor acidity improves antitumor responses to immunotherapeutic interventions. Cancer Research. PMID 26719539 DOI: 10.1158/0008-5472.Can-15-1743  0.393
2015 Damaghi M, Tafreshi NK, Lloyd MC, Sprung R, Estrella V, Wojtkowiak JW, Morse DL, Koomen JM, Bui MM, Gatenby RA, Gillies RJ. Chronic acidosis in the tumour microenvironment selects for overexpression of LAMP2 in the plasma membrane. Nature Communications. 6: 8752. PMID 26658462 DOI: 10.1038/Ncomms9752  0.419
2015 Gillies RJ, Kinahan PE, Hricak H. Radiomics: Images Are More than Pictures, They Are Data. Radiology. 151169. PMID 26579733 DOI: 10.1148/radiol.2015151169  0.387
2015 Schabath MB, Gillies RJ. Noninvasive Quantitative Imaging-based Biomarkers and Lung Cancer Screening. American Journal of Respiratory and Critical Care Medicine. 192: 654-6. PMID 26371810 DOI: 10.1164/rccm.201506-1160ED  0.32
2015 Stephen RM, Jha AK, Roe DJ, Trouard TP, Galons JP, Kupinski MA, Frey G, Cui H, Squire S, Pagel MD, Rodriguez JJ, Gillies RJ, Stopeck AT. Diffusion MRI with Semi-Automated Segmentation Can Serve as a Restricted Predictive Biomarker of the Therapeutic Response of Liver Metastasis. Magnetic Resonance Imaging. PMID 26284600 DOI: 10.1016/J.Mri.2015.08.006  0.357
2015 Tafreshi NK, Lloyd MC, Proemsey JB, Bui MM, Kim J, Gillies RJ, Morse DL. Evaluation of CAIX and CAXII Expression in Breast Cancer at Varied O2 Levels: CAIX is the Superior Surrogate Imaging Biomarker of Tumor Hypoxia. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. PMID 26276155 DOI: 10.1007/s11307-015-0885-x  0.397
2015 Leijenaar RT, Nalbantov G, Carvalho S, van Elmpt WJ, Troost EG, Boellaard R, Aerts HJ, Gillies RJ, Lambin P. The effect of SUV discretization in quantitative FDG-PET Radiomics: the need for standardized methodology in tumor texture analysis. Scientific Reports. 5: 11075. PMID 26242464 DOI: 10.1038/Srep11075  0.436
2015 Rajeshkumar NV, Dutta P, Yabuuchi S, de Wilde RF, Matrinez GV, Le A, Kamphorst JJ, Rabinowitz JD, Jain SK, Hidalgo M, Dang CV, Gillies RJ, Maitra A. Therapeutic targeting of the Warburg effect in pancreatic cancer relies on an absence of p53 function. Cancer Research. PMID 26113084 DOI: 10.1158/0008-5472.Can-15-0108  0.515
2015 Chaudhury B, Zhou M, Goldgof DB, Hall LO, Gatenby RA, Gillies RJ, Patel BK, Weinfurtner RJ, Drukteinis JS. Heterogeneity in intratumoral regions with rapid gadolinium washout correlates with estrogen receptor status and nodal metastasis. Journal of Magnetic Resonance Imaging : Jmri. PMID 25884277 DOI: 10.1002/Jmri.24921  0.443
2015 Robertson-Tessi M, Gillies RJ, Gatenby RA, Anderson AR. Impact of metabolic heterogeneity on tumor growth, invasion, and treatment outcomes. Cancer Research. 75: 1567-79. PMID 25878146 DOI: 10.1158/0008-5472.Can-14-1428  0.475
2015 Gillies RJ, Gatenby RA. Metabolism and its sequelae in cancer evolution and therapy. Cancer Journal (Sudbury, Mass.). 21: 88-96. PMID 25815848 DOI: 10.1097/PPO.0000000000000102  0.469
2015 Verduzco D, Lloyd M, Xu L, Ibrahim-Hashim A, Balagurunathan Y, Gatenby RA, Gillies RJ. Intermittent hypoxia selects for genotypes and phenotypes that increase survival, invasion, and therapy resistance. Plos One. 10: e0120958. PMID 25811878 DOI: 10.1371/Journal.Pone.0120958  0.464
2015 Grove O, Berglund AE, Schabath MB, Aerts HJ, Dekker A, Wang H, Velazquez ER, Lambin P, Gu Y, Balagurunathan Y, Eikman E, Gatenby RA, Eschrich S, Gillies RJ. Quantitative computed tomographic descriptors associate tumor shape complexity and intratumor heterogeneity with prognosis in lung adenocarcinoma. Plos One. 10: e0118261. PMID 25739030 DOI: 10.1371/Journal.Pone.0118261  0.435
2015 Wojtkowiak JW, Cornnell HC, Matsumoto S, Saito K, Takakusagi Y, Dutta P, Kim M, Zhang X, Leos R, Bailey KM, Martinez G, Lloyd MC, Weber C, Mitchell JB, Lynch RM, ... ... Gillies RJ, et al. Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302. Cancer & Metabolism. 3: 2. PMID 25635223 DOI: 10.1186/S40170-014-0026-Z  0.481
2015 Kam Y, Das T, Tian H, Foroutan P, Ruiz E, Martinez G, Minton S, Gillies RJ, Gatenby RA. Sweat but no gain: inhibiting proliferation of multidrug resistant cancer cells with "ersatzdroges". International Journal of Cancer. Journal International Du Cancer. 136: E188-96. PMID 25156304 DOI: 10.1002/ijc.29158  0.441
2015 Enriquez-Navas PM, Wojtkowiak J, Ruiz E, Hassan S, Gillies RJ, Gatenby RA. Abstract B11: Adaptive therapy modifies tumor vascularity Molecular Cancer Therapeutics. 14. DOI: 10.1158/1538-8514.Tumang15-B11  0.394
2015 Robertson-Tessi M, Gillies RJ, Gatenby RA, Anderson AR. Abstract B05: Harnessing heterogeneity to design better combination therapies Cancer Research. 75. DOI: 10.1158/1538-7445.Chtme14-B05  0.398
2015 El-Kenawi AE, Ibrahim-Hashim AA, Luddy KA, Pilon-Thomas SA, Gatenby RA, Gillies RJ. Abstract 3213: Extracellular acidosis alters polarization of macrophages Cancer Research. 75: 3213-3213. DOI: 10.1158/1538-7445.Am2015-3213  0.363
2015 Damaghi M, Sprung R, Tafreshi N, Estrella V, Koomen J, Morse D, Gillies R. Abstract 1265: LAMP2 overexpression in the plasma membrane of breast cancer cells in response of chronic acidosis as a new imaging and therapeutic target Cancer Research. 75: 1265-1265. DOI: 10.1158/1538-7445.Am2015-1265  0.414
2015 Gillies RJ. Abstract CN01-01: The radiology reading room of the future Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-Cn01-01  0.372
2015 Grossmann P, Grove O, El-Hachem N, Velazquez ER, Parmar C, Leijenaar R, Haibe-Kains B, Lambin P, Gillies R, Aerts H. TU-CD-BRB-02: BEST IN PHYSICS (JOINT IMAGING-THERAPY): Identification of Molecular Phenotypes by Integrating Radiomics and Genomics Medical Physics. 42: 3602-3602. DOI: 10.1118/1.4925587  0.453
2015 Farhidzadeh H, Chaudhury B, Zhou M, Goldgof DB, Hall LO, Gatenby RA, Gillies RJ, Raghavan M. Prediction of treatment outcome in soft tissue sarcoma based on radiologically defined habitats Progress in Biomedical Optics and Imaging - Proceedings of Spie. 9414. DOI: 10.1117/12.2082324  0.451
2015 Chaudhury B, Zhou M, Goldgof DB, Hall LO, Gatenby RA, Gillies RJ, Drukteinis JS. Identifying metastatic breast tumors using textural kinetic features of a contrast based habitat in DCE-MRI Progress in Biomedical Optics and Imaging - Proceedings of Spie. 9414. DOI: 10.1117/12.2081386  0.47
2015 Zhou M, Hall LO, Goldgof DB, Gillies RJ, Gatenby RA. Imbalanced learning for clinical survival group prediction of brain tumor patients Progress in Biomedical Optics and Imaging - Proceedings of Spie. 9414. DOI: 10.1117/12.2075606  0.407
2015 Zhou M, Hall LO, Goldgof DB, Russo R, Gillies RJ, Gatenby RA. Decoding brain cancer dynamics: A quantitative histogram-based approach using temporal MRI Progress in Biomedical Optics and Imaging - Proceedings of Spie. 9414. DOI: 10.1117/12.2075545  0.465
2015 Leijenaar RTH, Nalbantov G, Carvalho S, Elmpt WJCV, Troost EGC, Boellaard R, Aerts HJWL, Gillies RJ, Lambin P. PO-0968: The effect of SUV discretization in PET Radiomics: the need for standardized methodology in tumor texture analysis Radiotherapy and Oncology. 115. DOI: 10.1016/S0167-8140(15)40960-0  0.412
2014 Epstein T, Xu L, Gillies R, Gatenby R. SU-E-J-102: Separation of Metabolic Supply and Demand: From Power Grid Economics to Cancer Metabolism. Medical Physics. 41: 179. PMID 28037224 DOI: 10.1118/1.4888154  0.419
2014 Dutta P, Martinez GV, Gillies RJ. Nanodiamond as a New Hyperpolarizing Agent and Its (13)C MRS. The Journal of Physical Chemistry Letters. 5: 597-600. PMID 26276615 DOI: 10.1021/jz402659t  0.345
2014 Bailey KM, Cornnell HH, Ibrahim-Hashim A, Wojtkowiak JW, Hart CP, Zhang X, Leos R, Martinez GV, Baker AF, Gillies RJ. Evaluation of the "steal" phenomenon on the efficacy of hypoxia activated prodrug TH-302 in pancreatic cancer. Plos One. 9: e113586. PMID 25532146 DOI: 10.1371/Journal.Pone.0113586  0.371
2014 Colen R, Foster I, Gatenby R, Giger ME, Gillies R, Gutman D, Heller M, Jain R, Madabhushi A, Madhavan S, Napel S, Rao A, Saltz J, Tatum J, Verhaak R, et al. NCI Workshop Report: Clinical and Computational Requirements for Correlating Imaging Phenotypes with Genomics Signatures. Translational Oncology. 7: 556-69. PMID 25389451 DOI: 10.1016/J.Tranon.2014.07.007  0.415
2014 Takakusagi Y, Matsumoto S, Saito K, Matsuo M, Kishimoto S, Wojtkowiak JW, DeGraff W, Kesarwala AH, Choudhuri R, Devasahayam N, Subramanian S, Munasinghe JP, Gillies RJ, Mitchell JB, Hart CP, et al. Pyruvate induces transient tumor hypoxia by enhancing mitochondrial oxygen consumption and potentiates the anti-tumor effect of a hypoxia-activated prodrug TH-302. Plos One. 9: e107995. PMID 25254649 DOI: 10.1371/Journal.Pone.0107995  0.328
2014 Balagurunathan Y, Kumar V, Gu Y, Kim J, Wang H, Liu Y, Goldgof DB, Hall LO, Korn R, Zhao B, Schwartz LH, Basu S, Eschrich S, Gatenby RA, Gillies RJ. Test-retest reproducibility analysis of lung CT image features. Journal of Digital Imaging. 27: 805-23. PMID 24990346 DOI: 10.1007/S10278-014-9716-X  0.417
2014 Epstein T, Xu L, Gillies RJ, Gatenby RA. Separation of metabolic supply and demand: aerobic glycolysis as a normal physiological response to fluctuating energetic demands in the membrane. Cancer & Metabolism. 2: 7. PMID 24982758 DOI: 10.1186/2049-3002-2-7  0.415
2014 Aerts HJ, Velazquez ER, Leijenaar RT, Parmar C, Grossmann P, Carvalho S, Cavalho S, Bussink J, Monshouwer R, Haibe-Kains B, Rietveld D, Hoebers F, Rietbergen MM, Leemans CR, Dekker A, ... ... Gillies RJ, et al. Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach. Nature Communications. 5: 4006. PMID 24892406 DOI: 10.1038/Ncomms5006  0.449
2014 Mountz JM, Yankeelov TE, Rubin DL, Buatti JM, Erikson BJ, Fennessy FM, Gillies RJ, Huang W, Jacobs MA, Kinahan PE, Laymon CM, Linden HM, Mankoff DA, Schwartz LH, Shim H, et al. Letter to cancer center directors: Progress in quantitative imaging as a means to predict and/or measure tumor response in cancer therapy trials. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 32: 2115-6. PMID 24868025 DOI: 10.1200/Jco.2014.55.8866  0.369
2014 Bailey KM, Wojtkowiak JW, Cornnell HH, Ribeiro MC, Balagurunathan Y, Hashim AI, Gillies RJ. Mechanisms of buffer therapy resistance. Neoplasia (New York, N.Y.). 16: 354-64.e1-3. PMID 24862761 DOI: 10.1016/J.Neo.2014.04.005  0.402
2014 Balagurunathan Y, Gu Y, Wang H, Kumar V, Grove O, Hawkins S, Kim J, Goldgof DB, Hall LO, Gatenby RA, Gillies RJ. Reproducibility and Prognosis of Quantitative Features Extracted from CT Images. Translational Oncology. 7: 72-87. PMID 24772210 DOI: 10.1593/Tlo.13844  0.427
2014 Zhou M, Hall L, Goldgof D, Russo R, Balagurunathan Y, Gillies R, Gatenby R. Radiologically defined ecological dynamics and clinical outcomes in glioblastoma multiforme: preliminary results. Translational Oncology. 7: 5-13. PMID 24772202 DOI: 10.1593/Tlo.13730  0.445
2014 Lloyd MC, Alfarouk KO, Verduzco D, Bui MM, Gillies RJ, Ibrahim ME, Brown JS, Gatenby RA. Vascular measurements correlate with estrogen receptor status. Bmc Cancer. 14: 279. PMID 24755315 DOI: 10.1186/1471-2407-14-279  0.414
2014 Zhang X, Pagel MD, Baker AF, Gillies RJ. Reproducibility of magnetic resonance perfusion imaging. Plos One. 9: e89797. PMID 24587040 DOI: 10.1371/journal.pone.0089797  0.416
2014 Khramtsov VV, Gillies RJ. Janus-faced tumor microenvironment and redox. Antioxidants & Redox Signaling. 21: 723-9. PMID 24512276 DOI: 10.1089/ars.2014.5864  0.355
2014 Oosterwijk E, Gillies RJ. Targeting ion transport in cancer. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 369: 20130107. PMID 24493755 DOI: 10.1098/rstb.2013.0107  0.34
2014 Mignion L, Dutta P, Martinez GV, Foroutan P, Gillies RJ, Jordan BF. Monitoring chemotherapeutic response by hyperpolarized 13C-fumarate MRS and diffusion MRI. Cancer Research. 74: 686-94. PMID 24285723 DOI: 10.1158/0008-5472.CAN-13-1914  0.461
2014 Luhach I, Idiyatullin D, Lynch CC, Corum C, Martinez GV, Garwood M, Gillies RJ. Rapid ex vivo imaging of PAIII prostate to bone tumor with SWIFT-MRI. Magnetic Resonance in Medicine. 72: 858-63. PMID 24155275 DOI: 10.1002/Mrm.24979  0.419
2014 Tafreshi NK, Lloyd MC, Bui MM, Gillies RJ, Morse DL. Carbonic anhydrase IX as an imaging and therapeutic target for tumors and metastases. Sub-Cellular Biochemistry. 75: 221-54. PMID 24146382 DOI: 10.1007/978-94-007-7359-2_12  0.373
2014 Drukteinis JS, Chaudhury B, Hall LO, Goldgof DB, Gillies R, Gatenby RA. Abstract 4188: Evolutionary dynamics in breast cancer via MRI textural kinetic analysis Cancer Research. 74: 4188-4188. DOI: 10.1158/1538-7445.Am2014-4188  0.381
2014 Schabath MB, Massion PP, Thompson ZJ, Balagurunathan Y, Goldof D, Eschrich SA, Gillies RJ. Abstract 3250: Survival of patients with incident lung cancer following screening by computed tomography in the National Lung Screening Trial Cancer Research. 74: 3250-3250. DOI: 10.1158/1538-7445.Am2014-3250  0.334
2014 Chaudhury B, Hall LO, Goldgof DB, Gatenby RA, Gillies RJ, Drukteinis JS. New method for predicting estrogen receptor status utilizing breast MRI texture kinetic analysis Proceedings of Spie. 9035. DOI: 10.1117/12.2043188  0.461
2014 Chaudhury B, Zhou M, Goldgof DB, Hall LO, Gatenby RA, Gillies RJ, Drukteinis JS. Using features from tumor subregions of breast DCE-MRI for estrogen receptor status prediction Conference Proceedings - Ieee International Conference On Systems, Man and Cybernetics. 2014: 2624-2629. DOI: 10.1109/smc.2014.6974323  0.305
2014 Hawkins SH, Korecki JN, Balagurunathan Y, Gu Y, Kumar V, Basu S, Hall LO, Goldgof DB, Gatenby RA, Gillies RJ. Predicting outcomes of nonsmall cell lung cancer using CT image features Ieee Access. 2: 1418-1426. DOI: 10.1109/Access.2014.2373335  0.441
2014 Aerts HJWL, Velazquez ER, Leijenaar RTH, Parmar C, Grossmann P, Carvalho S, Bussink J, Monshouwer R, Haibe-Kains B, Rietveld D, Hoebers F, Rietbergen MM, Leemans CR, Dekker A, Quackenbush J, ... Gillies RJ, et al. Corrigendum: Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach Nature Communications. 5: 4644. DOI: 10.1038/Ncomms5644  0.339
2013 Dutta P, Martinez GV, Gillies RJ. A New Horizon of DNP technology: Application to In-vivo (13)C Magnetic Resonance Spectroscopy and Imaging. Biophysical Reviews. 5: 271-281. PMID 26491489 DOI: 10.1007/s12551-012-0099-2  0.401
2013 Damaghi M, Wojtkowiak JW, Gillies RJ. pH sensing and regulation in cancer. Frontiers in Physiology. 4: 370. PMID 24381558 DOI: 10.3389/Fphys.2013.00370  0.34
2013 Foroutan P, Kreahling JM, Morse DL, Grove O, Lloyd MC, Reed D, Raghavan M, Altiok S, Martinez GV, Gillies RJ. Diffusion MRI and novel texture analysis in osteosarcoma xenotransplants predicts response to anti-checkpoint therapy. Plos One. 8: e82875. PMID 24358232 DOI: 10.1371/journal.pone.0082875  0.454
2013 Kim M, Gillies RJ, Rejniak KA. Current advances in mathematical modeling of anti-cancer drug penetration into tumor tissues. Frontiers in Oncology. 3: 278. PMID 24303366 DOI: 10.3389/Fonc.2013.00278  0.335
2013 Rothberg JM, Bailey KM, Wojtkowiak JW, Ben-Nun Y, Bogyo M, Weber E, Moin K, Blum G, Mattingly RR, Gillies RJ, Sloane BF. Acid-mediated tumor proteolysis: contribution of cysteine cathepsins. Neoplasia (New York, N.Y.). 15: 1125-37. PMID 24204192 DOI: 10.1593/Neo.13946  0.382
2013 Gatenby RA, Grove O, Gillies RJ. Quantitative imaging in cancer evolution and ecology. Radiology. 269: 8-15. PMID 24062559 DOI: 10.1148/radiol.13122697  0.495
2013 Carvalho S, Leijenaar RT, Velazquez ER, Oberije C, Parmar C, van Elmpt W, Reymen B, Troost EG, Oellers M, Dekker A, Gillies R, Aerts HJ, Lambin P. Prognostic value of metabolic metrics extracted from baseline positron emission tomography images in non-small cell lung cancer. Acta Oncologica (Stockholm, Sweden). 52: 1398-404. PMID 24047338 DOI: 10.3109/0284186X.2013.812795  0.345
2013 Leijenaar RT, Carvalho S, Velazquez ER, van Elmpt WJ, Parmar C, Hoekstra OS, Hoekstra CJ, Boellaard R, Dekker AL, Gillies RJ, Aerts HJ, Lambin P. Stability of FDG-PET Radiomics features: an integrated analysis of test-retest and inter-observer variability. Acta Oncologica (Stockholm, Sweden). 52: 1391-7. PMID 24047337 DOI: 10.3109/0284186X.2013.812798  0.41
2013 Barkey NM, Preihs C, Cornnell HH, Martinez G, Carie A, Vagner J, Xu L, Lloyd MC, Lynch VM, Hruby VJ, Sessler JL, Sill KN, Gillies RJ, Morse DL. Development and in vivo quantitative magnetic resonance imaging of polymer micelles targeted to the melanocortin 1 receptor. Journal of Medicinal Chemistry. 56: 6330-8. PMID 23863078 DOI: 10.1021/Jm4005576  0.431
2013 Dutta P, Le A, Vander Jagt DL, Tsukamoto T, Martinez GV, Dang CV, Gillies RJ. Evaluation of LDH-A and glutaminase inhibition in vivo by hyperpolarized 13C-pyruvate magnetic resonance spectroscopy of tumors. Cancer Research. 73: 4190-5. PMID 23722553 DOI: 10.1158/0008-5472.Can-13-0465  0.421
2013 Agus DB, Alexander JF, Arap W, Ashili S, Aslan JE, Austin RH, Backman V, Bethel KJ, Bonneau R, Chen WC, Chen-Tanyolac C, Choi NC, Curley SA, Dallas M, ... ... Gillies RJ, et al. A physical sciences network characterization of non-tumorigenic and metastatic cells. Scientific Reports. 3: 1449. PMID 23618955 DOI: 10.1038/Srep01449  0.566
2013 Kreahling JM, Foroutan P, Reed D, Martinez G, Razabdouski T, Bui MM, Raghavan M, Letson D, Gillies RJ, Altiok S. Wee1 inhibition by MK-1775 leads to tumor inhibition and enhances efficacy of gemcitabine in human sarcomas. Plos One. 8: e57523. PMID 23520471 DOI: 10.1371/journal.pone.0057523  0.455
2013 Brabez N, Nguyen KL, Saunders K, Lacy R, Xu L, Gillies RJ, Lynch RM, Chassaing G, Lavielle S, Hruby VJ. Synthesis and evaluation of cholecystokinin trimers: a multivalent approach to pancreatic cancer detection and treatment. Bioorganic & Medicinal Chemistry Letters. 23: 2422-5. PMID 23489620 DOI: 10.1016/J.Bmcl.2013.02.022  0.33
2013 Martinez GV, Navath S, Sewda K, Rao V, Foroutan P, Alleti R, Moberg VE, Ahad AM, Coppola D, Lloyd MC, Gillies RJ, Morse DL, Mash EA. Demonstration of a sucrose-derived contrast agent for magnetic resonance imaging of the GI tract. Bioorganic & Medicinal Chemistry Letters. 23: 2061-4. PMID 23481651 DOI: 10.1016/J.Bmcl.2013.02.008  0.357
2013 Gu Y, Kumar V, Hall LO, Goldgof DB, Li CY, Korn R, Bendtsen C, Velazquez ER, Dekker A, Aerts H, Lambin P, Li X, Tian J, Gatenby RA, Gillies RJ. Automated Delineation of Lung Tumors from CT Images Using a Single Click Ensemble Segmentation Approach. Pattern Recognition. 46: 692-702. PMID 23459617 DOI: 10.1016/J.Patcog.2012.10.005  0.375
2013 Kumar V, Nath K, Berman CG, Kim J, Tanvetyanon T, Chiappori AA, Gatenby RA, Gillies RJ, Eikman EA. Variance of SUVs for FDG-PET/CT is greater in clinical practice than under ideal study settings. Clinical Nuclear Medicine. 38: 175-82. PMID 23354032 DOI: 10.1097/RLU.0b013e318279ffdf  0.396
2013 Estrella V, Chen T, Lloyd M, Wojtkowiak J, Cornnell HH, Ibrahim-Hashim A, Bailey K, Balagurunathan Y, Rothberg JM, Sloane BF, Johnson J, Gatenby RA, Gillies RJ. Acidity generated by the tumor microenvironment drives local invasion. Cancer Research. 73: 1524-35. PMID 23288510 DOI: 10.1158/0008-5472.Can-12-2796  0.48
2013 Martinez-Zaguilan R, Tompkins LS, Gillies RJ, Lynch RM. Simultaneous analysis of intracellular pH and Ca²⁺ from cell populations. Methods in Molecular Biology (Clifton, N.J.). 937: 253-71. PMID 23007592 DOI: 10.1007/978-1-62703-086-1_16  0.285
2013 Robertson-Tessi M, Gillies RJ, Gatenby RA, Anderson ARA. Abstract A2: The importance of metabolic heterogeneity and its consequences on tumor invasion, metastatic growth, and treatment Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-A2  0.409
2013 Rejniak KA, Kim M, Wojtkowiak J, Gillies RJ. Abstract B49: The interplay between hypoxia-activated drugs and the microenvironment in pancreatic cancers: a computational study Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-B49  0.359
2013 JeuneSmith Y, Cohen AS, Tafreshi NK, Vagner J, Gillies R, Morse D. Abstract 5519:In vivofluorescence lifetime imaging differentiates the bound versus unbound status of a cell surface receptor targeted ligand. Cancer Research. 73: 5519-5519. DOI: 10.1158/1538-7445.Am2013-5519  0.36
2013 Verduzco D, Gatenby R, Gillies R. Abstract 5002: Intermittent hypoxia selects for increased carcinogenicity in breast epithelial cells. Cancer Research. 73: 5002-5002. DOI: 10.1158/1538-7445.Am2013-5002  0.369
2013 Bailey KM, Wojtkowiak JW, Hashim AAI, Gillies RJ. Abstract 3941: Manipulating the tumor microenvironment for therapeutic benefit: identifying mechanisms of buffer resistance. Cancer Research. 73: 3941-3941. DOI: 10.1158/1538-7445.Am2013-3941  0.401
2013 Zhou M, Hall LO, Goldgof DB, Gillies RJ, Gatenby RA. Survival time prediction of patients with glioblastoma multiforme tumors using spatial distance measurement Proceedings of Spie - the International Society For Optical Engineering. 8670. DOI: 10.1117/12.2007699  0.465
2013 Martinez-Zaguilan R, Tompkins LS, Gillies RJ, Lynch RM. Simultaneous analysis of intracellular pH and Ca2+ from cell populations Methods in Molecular Biology. 937: 253-271. DOI: 10.1007/978-1-62703-86-1_16  0.274
2012 Ribeiro MD, Silva AS, Bailey KM, Kumar NB, Sellers TA, Gatenby RA, Ibrahim-Hashim A, Gillies RJ. Buffer Therapy for Cancer. Journal of Nutrition & Food Sciences. 2: 6. PMID 24371544 DOI: 10.4172/2155-9600.S2-006  0.418
2012 Stephen RM, Pagel MD, Brown K, Baker AF, Meuillet EJ, Gillies RJ. Monitoring the development of xenograft triple-negative breast cancer models using diffusion-weighted magnetic resonance imaging. Experimental Biology and Medicine (Maywood, N.J.). 237: 1273-80. PMID 23239438 DOI: 10.1258/Ebm.2012.011326  0.493
2012 Xu L, Josan JS, Vagner J, Caplan MR, Hruby VJ, Mash EA, Lynch RM, Morse DL, Gillies RJ. Heterobivalent ligands target cell-surface receptor combinations in vivo. Proceedings of the National Academy of Sciences of the United States of America. 109: 21295-300. PMID 23236171 DOI: 10.1073/Pnas.1211762109  0.335
2012 Rios Velazquez E, Aerts HJ, Gu Y, Goldgof DB, De Ruysscher D, Dekker A, Korn R, Gillies RJ, Lambin P. A semiautomatic CT-based ensemble segmentation of lung tumors: comparison with oncologists' delineations and with the surgical specimen. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 105: 167-73. PMID 23157978 DOI: 10.1016/J.Radonc.2012.09.023  0.345
2012 Gillies RJ, Flowers CI, Drukteinis JS, Gatenby RA. A unifying theory of carcinogenesis, and why targeted therapy doesn't work. European Journal of Radiology. 81: S48-50. PMID 23083599 DOI: 10.1016/S0720-048X(12)70018-9  0.388
2012 Tafreshi NK, Gillies RJ, Morse DL. Molecular imaging of breast cancer lymph node metastasis. European Journal of Radiology. 81: S160-1. PMID 23083574 DOI: 10.1016/S0720-048X(12)70067-0  0.383
2012 Silva AS, Kam Y, Khin ZP, Minton SE, Gillies RJ, Gatenby RA. Evolutionary approaches to prolong progression-free survival in breast cancer. Cancer Research. 72: 6362-70. PMID 23066036 DOI: 10.1158/0008-5472.CAN-12-2235  0.431
2012 Chinnaiyan P, Kensicki E, Bloom G, Prabhu A, Sarcar B, Kahali S, Eschrich S, Qu X, Forsyth P, Gillies R. The metabolomic signature of malignant glioma reflects accelerated anabolic metabolism. Cancer Research. 72: 5878-88. PMID 23026133 DOI: 10.1158/0008-5472.Can-12-1572-T  0.31
2012 Bailey KM, Wojtkowiak JW, Hashim AI, Gillies RJ. Targeting the metabolic microenvironment of tumors. Advances in Pharmacology (San Diego, Calif.). 65: 63-107. PMID 22959024 DOI: 10.1016/B978-0-12-397927-8.00004-X  0.398
2012 Kumar V, Gu Y, Basu S, Berglund A, Eschrich SA, Schabath MB, Forster K, Aerts HJ, Dekker A, Fenstermacher D, Goldgof DB, Hall LO, Lambin P, Balagurunathan Y, Gatenby RA, ... Gillies RJ, et al. Radiomics: the process and the challenges. Magnetic Resonance Imaging. 30: 1234-48. PMID 22898692 DOI: 10.1016/J.Mri.2012.06.010  0.412
2012 Wojtkowiak JW, Gillies RJ. Autophagy on acid. Autophagy. 8: 1688-9. PMID 22874557 DOI: 10.4161/Auto.21501  0.42
2012 Wojtkowiak JW, Rothberg JM, Kumar V, Schramm KJ, Haller E, Proemsey JB, Lloyd MC, Sloane BF, Gillies RJ. Chronic autophagy is a cellular adaptation to tumor acidic pH microenvironments. Cancer Research. 72: 3938-47. PMID 22719070 DOI: 10.1158/0008-5472.Can-11-3881  0.382
2012 Ibrahim-Hashim A, Cornnell HH, Abrahams D, Lloyd M, Bui M, Gillies RJ, Gatenby RA. Systemic buffers inhibit carcinogenesis in TRAMP mice. The Journal of Urology. 188: 624-31. PMID 22704445 DOI: 10.1016/j.juro.2012.03.113  0.45
2012 Gillies RJ, Verduzco D, Gatenby RA. Evolutionary dynamics of carcinogenesis and why targeted therapy does not work. Nature Reviews. Cancer. 12: 487-93. PMID 22695393 DOI: 10.1038/nrc3298  0.433
2012 Cunningham J, Estrella V, Lloyd M, Gillies R, Frieden BR, Gatenby R. Intracellular electric field and pH optimize protein localization and movement. Plos One. 7: e36894. PMID 22623963 DOI: 10.1371/journal.pone.0036894  0.378
2012 Cárdenas-Rodríguez J, Li Y, Galons JP, Cornnell H, Gillies RJ, Pagel MD, Baker AF. Imaging biomarkers to monitor response to the hypoxia-activated prodrug TH-302 in the MiaPaCa2 flank xenograft model. Magnetic Resonance Imaging. 30: 1002-9. PMID 22554971 DOI: 10.1016/j.mri.2012.02.015  0.444
2012 D'Silva L, Pola A, Dutta P, Martinez GV, Sprenger P, Gillies RJ, Kuchel PW, Sendhil Velan S. Slow relaxation of longitudinal multispin orders in weakly and strongly coupled two-spin systems. Magnetic Resonance in Chemistry : Mrc. 50: 443-8. PMID 22552892 DOI: 10.1002/mrc.3820  0.32
2012 Martin NK, Robey IF, Gaffney EA, Gillies RJ, Gatenby RA, Maini PK. Predicting the safety and efficacy of buffer therapy to raise tumour pHe: an integrative modelling study. British Journal of Cancer. 106: 1280-7. PMID 22382688 DOI: 10.1038/Bjc.2012.58  0.419
2012 Lambin P, Rios-Velazquez E, Leijenaar R, Carvalho S, Stiphout RGPMv, Granton P, Zegers CML, Gillies R, Boellard R, Dekker A, Aerts HJWL. Radiomics: extracting more information from medical images using advanced feature analysis. European Journal of Cancer. 48: 441-446. PMID 22257792 DOI: 10.1016/J.Ejca.2011.11.036  0.4
2012 Tafreshi NK, Bui MM, Bishop K, Lloyd MC, Enkemann SA, Lopez AS, Abrahams D, Carter BW, Vagner J, Grobmyer SR, Gobmyer SR, Gillies RJ, Morse DL. Noninvasive detection of breast cancer lymph node metastasis using carbonic anhydrases IX and XII targeted imaging probes. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 207-19. PMID 22016510 DOI: 10.1158/1078-0432.CCR-11-0238  0.314
2012 Kreahling J, Reed DR, Foroutan P, Martinez G, Gillies R, Altiok S. Activity of MK1775, a selective Wee1 inhibitor, alone or in combination with gemcitabine, in sarcomas. Journal of Clinical Oncology. 30: 10084-10084. DOI: 10.1200/Jco.2012.30.15_Suppl.10084  0.345
2012 Rajeshkumar NV, Dutta P, Kamphorst J, Le A, Yabuuchi S, Wilde RFd, Campbell NR, Oliveira ED, Jesus-Acosta AD, Rabinowitz J, Laheru D, Jain SK, Hidalgo M, Thompson CB, Hoff DDV, ... Gillies RJ, et al. Abstract LB-61: Targeting cancer cell metabolism in pancreatic cancer: p53, a key regulator of glycolysis and a major factor deciding the outcome of targeting the Warburg effect Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-61  0.434
2012 Tafreshi NK, Barkey NM, McCardle TW, Enkemann SA, Estrella VC, Chen T, Vagner J, Gillies RJ, Morse DL. Abstract 4557: Development of a melanocortin receptor 1 targeted probe for molecular imaging of melanoma Cancer Research. 72: 4557-4557. DOI: 10.1158/1538-7445.Am2012-4557  0.369
2012 Khin Z, Hazlehurst L, Shain K, Gillies R, Gatenby R, Silva AS. Abstract 3194: Reverse engineering the interplay between multiple myeloma and microenvironment Cancer Research. 72: 3194-3194. DOI: 10.1158/1538-7445.Am2012-3194  0.364
2012 Sewda K, Wojtkowiak JW, Enkemann S, Lopez AS, Coppola D, Shibata D, Yeatman TJ, Gillies RJ, Morse DL. Abstract 1156: Cell-surface marker discovery for colorectal cancer Cancer Research. 72: 1156-1156. DOI: 10.1158/1538-7445.Am2012-1156  0.35
2011 Ibrahim-Hashim A, Wojtkowiak JW, de Lourdes Coelho Ribeiro M, Estrella V, Bailey KM, Cornnell HH, Gatenby RA, Gillies RJ. Free Base Lysine Increases Survival and Reduces Metastasis in Prostate Cancer Model. Journal of Cancer Science & Therapy. PMID 24032073 DOI: 10.4172/1948-5956.S1-004  0.495
2011 Wojtkowiak JW, Verduzco D, Schramm KJ, Gillies RJ. Drug resistance and cellular adaptation to tumor acidic pH microenvironment. Molecular Pharmaceutics. 8: 2032-8. PMID 21981633 DOI: 10.1021/Mp200292C  0.371
2011 Rao V, Alleti R, Xu L, Tafreshi NK, Morse DL, Gillies RJ, Mash EA. A sucrose-derived scaffold for multimerization of bioactive peptides. Bioorganic & Medicinal Chemistry. 19: 6474-82. PMID 21940174 DOI: 10.1016/J.Bmc.2011.08.053  0.34
2011 Ibrahim Hashim A, Cornnell HH, Coelho Ribeiro Mde L, Abrahams D, Cunningham J, Lloyd M, Martinez GV, Gatenby RA, Gillies RJ. Reduction of metastasis using a non-volatile buffer. Clinical & Experimental Metastasis. 28: 841-9. PMID 21861189 DOI: 10.1007/s10585-011-9415-7  0.484
2011 Gatenby RA, Gillies RJ. Integrated imaging of cancer metabolism. Academic Radiology. 18: 929-31. PMID 21718952 DOI: 10.1016/j.acra.2011.05.005  0.448
2011 Huynh AS, Abrahams DF, Torres MS, Baldwin MK, Gillies RJ, Morse DL. Development of an orthotopic human pancreatic cancer xenograft model using ultrasound guided injection of cells. Plos One. 6: e20330. PMID 21647423 DOI: 10.1371/journal.pone.0020330  0.406
2011 Martinez GV, Zhang X, García-Martín ML, Morse DL, Woods M, Sherry AD, Gillies RJ. Imaging the extracellular pH of tumors by MRI after injection of a single cocktail of T1 and T2 contrast agents. Nmr in Biomedicine. 24: 1380-91. PMID 21604311 DOI: 10.1002/Nbm.1701  0.404
2011 Gatenby RA, Gillies RJ, Brown JS. Of cancer and cave fish. Nature Reviews. Cancer. 11: 237-8. PMID 21548400 DOI: 10.1038/Nrc3036  0.433
2011 Perfahl H, Byrne HM, Chen T, Estrella V, Alarcón T, Lapin A, Gatenby RA, Gillies RJ, Lloyd MC, Maini PK, Reuss M, Owen MR. Multiscale modelling of vascular tumour growth in 3D: the roles of domain size and boundary conditions. Plos One. 6: e14790. PMID 21533234 DOI: 10.1371/journal.pone.0014790  0.354
2011 Hashim AI, Zhang X, Wojtkowiak JW, Martinez GV, Gillies RJ. Imaging pH and metastasis. Nmr in Biomedicine. 24: 582-91. PMID 21387439 DOI: 10.1002/Nbm.1644  0.507
2011 Tafreshi NK, Enkemann SA, Bui MM, Lloyd MC, Abrahams D, Huynh AS, Kim J, Grobmyer SR, Carter WB, Vagner J, Gillies RJ, Morse DL. A mammaglobin-A targeting agent for noninvasive detection of breast cancer metastasis in lymph nodes. Cancer Research. 71: 1050-9. PMID 21169406 DOI: 10.1158/0008-5472.CAN-10-3091  0.332
2011 Martin NK, Gaffney EA, Gatenby RA, Gillies RJ, Robey IF, Maini PK. A mathematical model of tumour and blood pHe regulation: The HCO3-/CO2 buffering system. Mathematical Biosciences. 230: 1-11. PMID 21167185 DOI: 10.1016/J.Mbs.2010.12.002  0.398
2011 Gillies RJ, Goldgof D, Hall L, Gatenby R, Kumar V, Gu Y, Basu S, Kim J, Gray J, Tockman M, Song D, Eschrich S. Abstract ED01-02: Imaging ‘omics in cancer detection Cancer Prevention Research. 4. DOI: 10.1158/1940-6207.Prev-11-Ed01-02  0.37
2011 Tafreshi NK, Bui MM, Bishop K, Lloyd MC, Enkemann SA, Vagner J, Grobmyer SR, Gillies RJ, Morse DL. Abstract 5301: Development of CAIX and CAXII targeting imaging probes for non-invasive detection of metastatic breast cancer in axillary lymph nodes Cancer Research. 71: 5301-5301. DOI: 10.1158/1538-7445.Am2011-5301  0.357
2011 Robertson-Tessi M, Estrella VC, Chen T, Lloyd MC, Gillies RJ, Gatenby RA, Anderson ARA. Abstract 53: Exploiting heterogeneity to develop better treatment strategies using an evolutionary multiscale mathematical model of tumor-vessel interactions Cancer Research. 71: 53-53. DOI: 10.1158/1538-7445.Am2011-53  0.388
2011 Cornnell HH, Baker AF, Torres TA, Hashim AI, Rejniak KA, Gatenby RA, Gillies RJ. Abstract 3520: The use of vasodilators to enhance efficacy of hypoxia or acid activated prodrugs in pancreatic cancers Cancer Research. 71: 3520-3520. DOI: 10.1158/1538-7445.Am2011-3520  0.418
2011 Basanta D, Hashim AI, Gillies RJ, Gatenby RA, Ayala GE, Hayward SW, Anderson AR. Abstract 34: Microenvironmental independence or co-option: How tumour-stromal interactions influence prostate cancer lethal outcomes Cancer Research. 71: 34-34. DOI: 10.1158/1538-7445.Am2011-34  0.34
2011 Sewda K, Enkemann S, Gillies RJ, Morse DL. Abstract 3178: Identification and validation of markers for colon adenoma and adenocarcinoma Cancer Research. 71: 3178-3178. DOI: 10.1158/1538-7445.Am2011-3178  0.352
2011 Scott JG, McFarland CM, Wojtkowiak JW, Basanta D, Anderson ARA, Gillies RJ, Morse DL, Leonid MA. Abstract 2437: Genotypic determinants of metastatic fitness: A delicate balance between passenger and driver mutations Cancer Research. 71: 2437-2437. DOI: 10.1158/1538-7445.Am2011-2437  0.39
2011 Silva AS, Anderson A, Gillies R, Gatenby R. Abstract 21: Understanding the progression and chemotherapy resistance of Multiple Myeloma in the bone marrow through evolutionary computational models and in vitro experiments Cancer Research. 71: 21-21. DOI: 10.1158/1538-7445.Am2011-21  0.374
2011 Wojtkowiak JW, Barkey NM, Kumar V, Lloyd MC, Gatenby RA, Gillies RJ. Abstract 1254: Altered lipid and glucose metabolism is a cellular adaptation to tumor acidic microenvironments Cancer Research. 71: 1254-1254. DOI: 10.1158/1538-7445.Am2011-1254  0.401
2011 Basu S, Hall LO, Goldgof DB, Gu Y, Kumar V, Choi J, Gillies RJ, Gatenby RA. Developing a classifier model for lung tumors in CT-scan images Conference Proceedings - Ieee International Conference On Systems, Man and Cybernetics. 1306-1312. DOI: 10.1109/ICSMC.2011.6083840  0.329
2010 Gatenby RA, Gillies RJ, Brown JS. Evolutionary dynamics of cancer prevention. Nature Reviews. Cancer. 10: 526-7. PMID 21137109 DOI: 10.1038/Nrc2892  0.42
2010 Zhang X, Lin Y, Gillies RJ. Tumor pH and its measurement. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 51: 1167-70. PMID 20660380 DOI: 10.2967/jnumed.109.068981  0.47
2010 Gillies RJ, Anderson AR, Gatenby RA, Morse DL. The biology underlying molecular imaging in oncology: from genome to anatome and back again. Clinical Radiology. 65: 517-21. PMID 20541651 DOI: 10.1016/J.Crad.2010.04.005  0.411
2010 Morse DL, Balagurunathan Y, Hostetter G, Trissal M, Tafreshi NK, Burke N, Lloyd M, Enkemann S, Coppola D, Hruby VJ, Gillies RJ, Han H. Identification of novel pancreatic adenocarcinoma cell-surface targets by gene expression profiling and tissue microarray. Biochemical Pharmacology. 80: 748-54. PMID 20510208 DOI: 10.1016/J.Bcp.2010.05.018  0.367
2010 Morse DL, Gillies RJ. Molecular imaging and targeted therapies. Biochemical Pharmacology. 80: 731-8. PMID 20399197 DOI: 10.1016/j.bcp.2010.04.011  0.303
2010 Morse DL, Hostetter G, Balagurunathan Y, Gillies RJ, Han H. Identification of pancreatic cancer-specific cell-surface markers for development of targeting ligands. Methods in Molecular Biology (Clifton, N.J.). 624: 195-210. PMID 20217597 DOI: 10.1007/978-1-60761-609-2_13  0.363
2010 Silva AS, Gatenby RA, Gillies RJ, Yunes JA. A quantitative theoretical model for the development of malignancy in ductal carcinoma in situ. Journal of Theoretical Biology. 262: 601-13. PMID 19887072 DOI: 10.1016/J.Jtbi.2009.10.031  0.462
2010 Schramm KJ, Vibet S, Oguz U, Wojtkowiak J, Koomen JM, Gillies RJ. Abstract A65: Changes in protein expression related to acidosis in the tumor microenvironment Cancer Epidemiology, Biomarkers & Prevention. 19. DOI: 10.1158/1055-9965.Disp-10-A65  0.373
2009 Rosca EV, Gillies RJ, Caplan MR. Glioblastoma targeting via integrins is concentration dependent. Biotechnology and Bioengineering. 104: 408-17. PMID 19575417 DOI: 10.1002/bit.22424  0.304
2009 Gatenby RA, Silva AS, Gillies RJ, Frieden BR. Adaptive therapy. Cancer Research. 69: 4894-903. PMID 19487300 DOI: 10.1158/0008-5472.CAN-08-3658  0.374
2009 Josan JS, Sankaranarayanan R, Handl HL, Fernandes S, Xu L, Vagner J, Gillies RJ, Hruby VJ. Heterobivalent ligands crosslink multiple cell-surface receptors--a step towards personal medicine. Advances in Experimental Medicine and Biology. 611: 413-4. PMID 19400245 DOI: 10.1007/978-0-387-73657-0_178  0.451
2009 Robey IF, Baggett BK, Kirkpatrick ND, Roe DJ, Dosescu J, Sloane BF, Hashim AI, Morse DL, Raghunand N, Gatenby RA, Gillies RJ. Bicarbonate increases tumor pH and inhibits spontaneous metastases. Cancer Research. 69: 2260-8. PMID 19276390 DOI: 10.1158/0008-5472.Can-07-5575  0.511
2009 Silva AS, Yunes JA, Gillies RJ, Gatenby RA. The potential role of systemic buffers in reducing intratumoral extracellular pH and acid-mediated invasion. Cancer Research. 69: 2677-84. PMID 19276380 DOI: 10.1158/0008-5472.Can-08-2394  0.478
2009 De Leon-Rodriguez LM, Lubag AJ, Malloy CR, Martinez GV, Gillies RJ, Sherry AD. Responsive MRI agents for sensing metabolism in vivo. Accounts of Chemical Research. 42: 948-57. PMID 19265438 DOI: 10.1021/Ar800237F  0.427
2009 Morse DL, Carroll D, Day S, Gray H, Sadarangani P, Murthi S, Job C, Baggett B, Raghunand N, Gillies RJ. Characterization of breast cancers and therapy response by MRS and quantitative gene expression profiling in the choline pathway. Nmr in Biomedicine. 22: 114-27. PMID 19016452 DOI: 10.1002/nbm.1318  0.485
2008 Balagurunathan Y, Morse DL, Hostetter G, Shanmugam V, Stafford P, Shack S, Pearson J, Trissal M, Demeure MJ, Von Hoff DD, Hruby VJ, Gillies RJ, Han H. Gene expression profiling-based identification of cell-surface targets for developing multimeric ligands in pancreatic cancer. Molecular Cancer Therapeutics. 7: 3071-80. PMID 18765825 DOI: 10.1158/1535-7163.Mct-08-0402  0.354
2008 Robey IF, Stephen RM, Brown KS, Baggett BK, Gatenby RA, Gillies RJ. Regulation of the Warburg effect in early-passage breast cancer cells. Neoplasia (New York, N.Y.). 10: 745-56. PMID 18670636 DOI: 10.1593/Neo.07724  0.397
2008 Trouard TP, Harkins KD, Divijak JL, Gillies RJ, Galons JP. Ischemia-induced changes of intracellular water diffusion in rat glioma cell cultures. Magnetic Resonance in Medicine. 60: 258-64. PMID 18666112 DOI: 10.1002/Mrm.21616  0.365
2008 Gillies RJ, Robey I, Gatenby RA. Causes and consequences of increased glucose metabolism of cancers Journal of Nuclear Medicine. 49: 24S-42S. PMID 18523064 DOI: 10.2967/Jnumed.107.047258  0.456
2008 Jennings D, Raghunand N, Gillies RJ. Imaging hemodynamics Cancer and Metastasis Reviews. 27: 589-613. PMID 18506397 DOI: 10.1007/s10555-008-9157-4  0.32
2008 Lope-Piedrafita S, Garcia-Martin ML, Galons JP, Gillies RJ, Trouard TP. Longitudinal diffusion tensor imaging in a rat brain glioma model. Nmr in Biomedicine. 21: 799-808. PMID 18470959 DOI: 10.1002/Nbm.1256  0.446
2008 Black KC, Kirkpatrick ND, Troutman TS, Xu L, Vagner J, Gillies RJ, Barton JK, Utzinger U, Romanowski M. Gold nanorods targeted to delta opioid receptor: plasmon-resonant contrast and photothermal agents. Molecular Imaging. 7: 50-7. PMID 18384724 DOI: 10.2310/7290.2008.0007  0.474
2008 Moellering RE, Black KC, Krishnamurty C, Baggett BK, Stafford P, Rain M, Gatenby RA, Gillies RJ. Acid treatment of melanoma cells selects for invasive phenotypes. Clinical & Experimental Metastasis. 25: 411-25. PMID 18301995 DOI: 10.1007/S10585-008-9145-7  0.485
2008 Gatenby RA, Gillies RJ. A microenvironmental model of carcinogenesis Nature Reviews Cancer. 8: 56-61. PMID 18059462 DOI: 10.1038/nrc2255  0.413
2008 Jordan BF, Galons JP, Gillies RJ. Post-treatment changes in tumor microenvironment: Dynamic contrast-enhanced and diffusion-weighted magnetic resonance imaging Cancer Imaging. 235-248. DOI: 10.1016/B978-012374212-4.50094-8  0.376
2007 Ackerstaff E, Artemov D, Gillies RJ, Bhujwalla ZM. Hypoxia and the presence of human vascular endothelial cells affect prostate cancer cell invasion and metabolism Neoplasia. 9: 1138-1151. PMID 18084621 DOI: 10.1593/neo.07568  0.449
2007 Gatenby RA, Smallbone K, Maini PK, Rose F, Averill J, Nagle RB, Worrall L, Gillies RJ. Cellular adaptations to hypoxia and acidosis during somatic evolution of breast cancer. British Journal of Cancer. 97: 646-53. PMID 17687336 DOI: 10.1038/sj.bjc.6603922  0.456
2007 Morse DL, Raghunand N, Sadarangani P, Murthi S, Job C, Day S, Howison C, Gillies RJ. Response of choline metabolites to docetaxel therapy is quantified in vivo by localized (31)P MRS of human breast cancer xenografts and in vitro by high-resolution (31)P NMR spectroscopy of cell extracts. Magnetic Resonance in Medicine. 58: 270-80. PMID 17654590 DOI: 10.1002/mrm.21333  0.494
2007 Gillies RJ, Gatenby RA. Adaptive landscapes and emergent phenotypes: Why do cancers have high glycolysis? Journal of Bioenergetics and Biomembranes. 39: 251-257. PMID 17624581 DOI: 10.1007/s10863-007-9085-y  0.468
2007 Gatenby RA, Gillies RJ. Glycolysis in cancer: A potential target for therapy International Journal of Biochemistry and Cell Biology. 39: 1358-1366. PMID 17499003 DOI: 10.1016/j.biocel.2007.03.021  0.475
2007 Gillies RJ, Gatenby RA. Hypoxia and adaptive landscapes in the evolution of carcinogenesis Cancer and Metastasis Reviews. 26: 311-317. PMID 17404691 DOI: 10.1007/s10555-007-9065-z  0.48
2007 Stephen RM, Gillies RJ. Promise and progress for functional and molecular imaging of response to targeted therapies Pharmaceutical Research. 24: 1172-1185. PMID 17385018 DOI: 10.1007/s11095-007-9250-3  0.428
2007 Morse DL, Galons JP, Payne CM, Jennings DL, Day S, Xia G, Gillies RJ. MRI-measured water mobility increases in response to chemotherapy via multiple cell-death mechanisms. Nmr in Biomedicine. 20: 602-14. PMID 17265424 DOI: 10.1002/Nbm.1127  0.449
2007 Smallbone K, Gatenby RA, Gillies RJ, Maini PK, Gavaghan DJ. Metabolic changes during carcinogenesis: potential impact on invasiveness. Journal of Theoretical Biology. 244: 703-13. PMID 17055536 DOI: 10.1016/j.jtbi.2006.09.010  0.457
2006 Tatum JL, Kelloff GJ, Gillies RJ, Arbeit JM, Brown JM, Chao KS, Chapman JD, Eckelman WC, Fyles AW, Giaccia AJ, Hill RP, Koch CJ, Krishna MC, Krohn KA, Lewis JS, et al. Hypoxia: importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy. International Journal of Radiation Biology. 82: 699-757. PMID 17118889 DOI: 10.1080/09553000601002324  0.483
2006 Sloane BF, Gillies RJ, Mohla S, Sogn JA, Menkens AE, Sullivan DC. I2 imaging: cancer biology and the tumor microenvironment. Cancer Research. 66: 11097-9. PMID 17114235 DOI: 10.1158/Aacr.Edb-Can-06-3102  0.401
2006 Gatenby RA, Gawlinski ET, Gmitro AF, Kaylor B, Gillies RJ. Acid-mediated tumor invasion: a multidisciplinary study. Cancer Research. 66: 5216-23. PMID 16707446 DOI: 10.1158/0008-5472.Can-05-4193  0.483
2006 Raghunand N, Jagadish B, Trouard TP, Galons JP, Gillies RJ, Mash EA. Redox-sensitive contrast agents for MRI based on reversible binding of thiols to serum albumin. Magnetic Resonance in Medicine. 55: 1272-80. PMID 16700014 DOI: 10.1002/Mrm.20904  0.355
2006 Borden MA, Martinez GV, Ricker J, Tsvetkova N, Longo M, Gillies RJ, Dayton PA, Ferrara KW. Lateral phase separation in lipid-coated microbubbles. Langmuir : the Acs Journal of Surfaces and Colloids. 22: 4291-7. PMID 16618177 DOI: 10.1021/La052841V  0.342
2006 Martinez-Zaguilan R, Tompkins LS, Gillies RJ, Lynch RM. Simultaneous analysis of intracellular pH and Ca2+ from cell populations. Methods in Molecular Biology (Clifton, N.J.). 312: 269-87. PMID 16422205  0.274
2006 Garcia-Martin ML, Martinez GV, Raghunand N, Sherry AD, Zhang S, Gillies RJ. High resolution pH(e) imaging of rat glioma using pH-dependent relaxivity. Magnetic Resonance in Medicine. 55: 309-15. PMID 16402385 DOI: 10.1002/Mrm.20773  0.446
2005 Martinez-Zaguilan R, Tompkins LS, Gillies RJ, Lynch RM. Simultaneous analysis of intracellular pH and Ca²+ from cell populations. Methods in Molecular Biology (Clifton, N.J.). 312: 269-87. PMID 21341106 DOI: 10.1385/1-59259-949-4:269  0.411
2005 Morse DL, Gray H, Payne CM, Gillies RJ. Docetaxel induces cell death through mitotic catastrophe in human breast cancer cells. Molecular Cancer Therapeutics. 4: 1495-504. PMID 16227398 DOI: 10.1158/1535-7163.Mct-05-0130  0.362
2005 Jordan BF, Black K, Robey IF, Runquist M, Powis G, Gillies RJ. Metabolite changes in HT-29 xenograft tumors following HIF-1alpha inhibition with PX-478 as studied by MR spectroscopy in vivo and ex vivo. Nmr in Biomedicine. 18: 430-9. PMID 16206237 DOI: 10.1002/Nbm.977  0.441
2005 Gillies RJ, Morse DL. In vivo magnetic resonance spectroscopy in cancer Annual Review of Biomedical Engineering. 7: 287-326. PMID 16004573 DOI: 10.1146/annurev.bioeng.7.060804.100411  0.43
2005 Galons JP, Lope-Piedrafita S, Divijak JL, Corum C, Gillies RJ, Trouard TP. Uncovering of intracellular water in cultured cells. Magnetic Resonance in Medicine. 54: 79-86. PMID 15968680 DOI: 10.1002/Mrm.20565  0.362
2005 Robey IF, Lien AD, Welsh SJ, Baggett BK, Gillies RJ. Hypoxia-inducible factor-1alpha and the glycolytic phenotype in tumors. Neoplasia (New York, N.Y.). 7: 324-30. PMID 15967109 DOI: 10.1593/Neo.04430  0.317
2005 Jordan BF, Runquist M, Raghunand N, Baker A, Williams R, Kirkpatrick L, Powis G, Gillies RJ. Dynamic contrast-enhanced and diffusion MRI show rapid and dramatic changes in tumor microenvironment in response to inhibition of HIF-1alpha using PX-478. Neoplasia (New York, N.Y.). 7: 475-85. PMID 15967100 DOI: 10.1593/Neo.04628  0.456
2005 Morse DL, Carroll D, Weberg L, Borgstrom MC, Ranger-Moore J, Gillies RJ. Determining suitable internal standards for mRNA quantification of increasing cancer progression in human breast cells by real-time reverse transcriptase polymerase chain reaction. Analytical Biochemistry. 342: 69-77. PMID 15958182 DOI: 10.1016/J.Ab.2005.03.034  0.318
2005 Jordan BF, Runquist M, Raghunand N, Gillies RJ, Tate WR, Powis G, Baker AF. The thioredoxin-1 inhibitor 1-methylpropyl 2-imidazolyl disulfide (PX-12) decreases vascular permeability in tumor xenografts monitored by dynamic contrast enhanced magnetic resonance imaging. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 529-36. PMID 15701837  0.352
2005 Gatenby RA, Vincent TL, Gillies RJ. Evolutionary dynamics in carcinogenesis Mathematical Models and Methods in Applied Sciences. 15: 1619-1638. DOI: 10.1142/S0218202505000911  0.41
2004 Baggett B, Roy R, Momen S, Morgan S, Tisi L, Morse D, Gillies RJ. Thermostability of firefly luciferases affects efficiency of detection by in vivo bioluminescence Molecular Imaging. 3: 324-332. PMID 15802049 DOI: 10.1162/1535350042973553  0.321
2004 Theilmann RJ, Borders R, Trouard TP, Xia G, Outwater E, Ranger-Moore J, Gillies RJ, Stopeck A. Changes in water mobility measured by diffusion MRI predict response of metastatic breast cancer to chemotherapy. Neoplasia (New York, N.Y.). 6: 831-7. PMID 15720810 DOI: 10.1593/Neo.03343  0.453
2004 Gillies RJ, Raghunand N, Garcia-Martin ML, Gatenby RA. pH imaging Ieee Engineering in Medicine and Biology Magazine. 23: 57-64. PMID 15565800 DOI: 10.1109/MEMB.2004.1360409  0.428
2004 Gatenby RA, Gillies RJ. Why do cancers have high aerobic glycolysis? Nature Reviews Cancer. 4: 891-899. PMID 15516961 DOI: 10.1038/nrc1478  0.472
2003 Raghunand N, Gatenby RA, Gillies RJ. Microenvironmental and cellular consequences of altered blood flow in tumours. The British Journal of Radiology. 76: S11-22. PMID 15456710 DOI: 10.1259/bjr/12913493  0.418
2003 Lukasik VM, Gillies RJ. Animal anaesthesia for in vivo magnetic resonance Nmr in Biomedicine. 16: 459-467. PMID 14696002 DOI: 10.1002/nbm.836  0.372
2003 Raghunand N, Mahoney BP, Gillies RJ. Tumor acidity, ion trapping and chemotherapeutics. II. pH-dependent partition coefficients predict importance of ion trapping on pharmacokinetics of weakly basic chemotherapeutic agents. Biochemical Pharmacology. 66: 1219-29. PMID 14505801 DOI: 10.1016/S0006-2952(03)00468-4  0.478
2003 Mahoney BP, Raghunand N, Baggett B, Gillies RJ. Tumor acidity, ion trapping and chemotherapeutics. I. Acid pH affects the distribution of chemotherapeutic agents in vitro. Biochemical Pharmacology. 66: 1207-18. PMID 14505800 DOI: 10.1016/S0006-2952(03)00467-2  0.451
2003 Gillies RJ, Hruby VJ. Expression-driven reverse engineering of targeted imaging and therapeutic agents. Expert Opinion On Therapeutic Targets. 7: 137-9. PMID 12667092 DOI: 10.1517/14728222.7.2.137  0.304
2003 Schornack PA, Gillies RJ. Contributions of cell metabolism and H+ diffusion to the acidic pH of tumors. Neoplasia (New York, N.Y.). 5: 135-45. PMID 12659686 DOI: 10.1016/S1476-5586(03)80005-2  0.406
2003 Raghunand N, Howison C, Sherry AD, Zhang S, Gillies RJ. Renal and systemic pH imaging by contrast-enhanced MRI Magnetic Resonance in Medicine. 49: 249-257. PMID 12541244 DOI: 10.1002/Mrm.10347  0.401
2003 Galons JP, Morse DL, Jennings DR, Gillies RJ. Diffusion-weighted MRI and response to anti-cancer therapies Israel Journal of Chemistry. 43: 91-101. DOI: 10.1560/Gj5M-Pp8R-Ghub-Vuup  0.387
2002 Gillies RJ. In vivo molecular imaging. Journal of Cellular Biochemistry. Supplement. 39: 231-8. PMID 12552622 DOI: 10.1002/jcb.10450  0.387
2002 Gillies RJ, Raghunand N, Karczmar GS, Bhujwalla ZM. MRI of the tumor microenvironment. Journal of Magnetic Resonance Imaging : Jmri. 16: 430-50. PMID 12353258 DOI: 10.1002/Jmri.10181  0.476
2002 Raghunand N, Zhang S, Sherry AD, Gillies RJ. In vivo magnetic resonance imaging of tissue pH using a novel pH-sensitive contrast agent, GdDOTA-4AmP Academic Radiology. 9: S481-S483. PMID 12188315 DOI: 10.1016/S1076-6332(03)80270-2  0.437
2002 Jennings D, Hatton BN, Guo J, Galons JP, Trouard TP, Raghunand N, Marshall J, Gillies RJ. Early response of prostate carcinoma xenografts to docetaxel chemotherapy monitored with diffusion MRI. Neoplasia (New York, N.Y.). 4: 255-62. PMID 11988845 DOI: 10.1038/Sj.Neo.7900225  0.421
2002 Bhujwalla ZM, Artemov D, Ballesteros P, Cerdan S, Gillies RJ, Solaiyappan M. Combined vascular and extracellular pH imaging of solid tumors Nmr in Biomedicine. 15: 114-119. PMID 11870907 DOI: 10.1002/Nbm.743  0.477
2001 Gillies RJ, Lynch RM. Frontiers in the measurement of cell and tissue pH. Novartis Foundation Symposium. 240: 7-19; discussion 19-. PMID 11727938 DOI: 10.1002/0470868716.Ch2  0.41
2001 Bhujwalla ZM, Artemov D, Aboagye E, Ackerstaff E, Gillies RJ, Natarajan K, Solaiyappan M. The physiological environment in cancer vascularization, invasion and metastasis Novartis Foundation Symposium. 240: 23-38. PMID 11727932 DOI: 10.1002/0470868716.Ch3  0.479
2001 Raghunand N, Gillies RJ. pH and chemotherapy Novartis Foundation Symposium. 240: 199-211. PMID 11727930 DOI: 10.1002/0470868716.Ch14  0.428
2001 Gillies RJ. The tumour microenvironment: causes and consequences of hypoxia and acidity. Introduction Novartis Foundation Symposium. 240: 1-6. PMID 11727923  0.252
2001 Raghunand N, Mahoney B, van Sluis R, Baggett B, Gillies RJ. Acute metabolic alkalosis enhances response of C3H mouse mammary tumors to the weak base mitoxantrone. Neoplasia (New York, N.Y.). 3: 227-35. PMID 11494116 DOI: 10.1038/sj/neo/7900151  0.463
2000 Raghunand N, Gillies RJ. pH and drug resistance in tumors. Drug Resistance Updates. 3: 39-47. PMID 11498364 DOI: 10.1054/Drup.2000.0119  0.432
2000 Gillies RJ. Causes and consequences of hypoxia and acidity in tumors - Novartis foundation symposium Trends in Molecular Medicine. 7: 47-49. PMID 11330256 DOI: 10.1016/S1471-4914(01)01913-X  0.333
2000 Pilatus U, Ackerstaff E, Artemov D, Mori N, Gillies RJ, Bhujwalla ZM. Imaging prostate cancer invasion with multi-nuclear magnetic resonance methods: the Metabolic Boyden Chamber. Neoplasia. 2: 273-279. PMID 10935513 DOI: 10.1038/Sj.Neo.7900089  0.461
2000 Evelhoch JL, Gillies RJ, Karczmar GS, Koutcher JA, Maxwell RJ, Nalcioglu O, Raghunand N, Ronen SM, Ross BD, Swartz HM. Applications of magnetic resonance in model systems: cancer therapeutics. Neoplasia (New York, N.Y.). 2: 152-65. PMID 10933074 DOI: 10.1038/Sj.Neo.7900078  0.487
2000 Gillies RJ, Bhujwalla ZM, Evelhoch J, Garwood M, Neeman M, Robinson SP, Sotak CH, Van Der Sanden B. Applications of magnetic resonance in model systems: tumor biology and physiology. Neoplasia (New York, N.Y.). 2: 139-51. PMID 10933073 DOI: 10.1038/Sj.Neo.7900076  0.47
1999 Gillies RJ, Schornack PA, Secomb TW, Raghunand N. Causes and Effects of Heterogeneous Perfusion in Tumors Neoplasia. 1: 197-207. PMID 10935474 DOI: 10.1038/Sj.Neo.7900037  0.451
1999 Galons JP, Altbach MI, Paine-Murrieta GD, Taylor CW, Gillies RJ. Early Increases in Breast Tumor Xenograft Water Mobility in Response to Paclitaxel Therapy Detected by Non-Invasive Diffusion Magnetic Resonance Imaging Neoplasia. 1: 113-117. PMID 10933044 DOI: 10.1038/Sj.Neo.7900009  0.48
1999 Raghunand N, Martínez-Zaguilán R, Wright SH, Gillies RJ. pH and drug resistance. II. Turnover of acidic vesicles and resistance to weakly basic chemotherapeutic drugs. Biochemical Pharmacology. 57: 1047-58. PMID 10796075 DOI: 10.1016/S0006-2952(99)00021-0  0.37
1999 Martínez-Zaguilán R, Raghunand N, Lynch RM, Bellamy W, Martinez GM, Rojas B, Smith D, Dalton WS, Gillies RJ. pH and drug resistance. I. Functional expression of plasmalemmal V-type H+-ATPase in drug-resistant human breast carcinoma cell lines. Biochemical Pharmacology. 57: 1037-46. PMID 10796074 DOI: 10.1016/S0006-2952(99)00022-2  0.398
1999 Raghunand N, He X, van Sluis R, Mahoney B, Baggett B, Taylor CW, Paine-Murrieta G, Roe D, Bhujwalla ZM, Gillies RJ. Enhancement of chemotherapy by manipulation of tumour pH. British Journal of Cancer. 80: 1005-11. PMID 10362108 DOI: 10.1038/Sj.Bjc.6690455  0.463
1999 Bhujwalla ZM, Aboagye EO, Gillies RJ, Chacko VP, Mendola CE, Backer JM. Nm23-transfected MDA-MB-435 human breast carcinoma cells form tumors with altered phospholipid metabolism and pH: A 31P nuclear magnetic resonance study in vivo and vitro Magnetic Resonance in Medicine. 41: 897-903. PMID 10332871 DOI: 10.1002/(SICI)1522-2594(199905)41:5<897::AID-MRM7>3.0.CO;2-T  0.48
1999 van Sluis R, Bhujwalla ZM, Raghunand N, Ballesteros P, Alvarez J, Cerdán S, Galons JP, Gillies RJ. In vivo imaging of extracellular pH using 1H MRSI. Magnetic Resonance in Medicine. 41: 743-50. PMID 10332850 DOI: 10.1002/(Sici)1522-2594(199904)41:4<743::Aid-Mrm13>3.0.Co;2-Z  0.439
1999 Martinez-Zaguilan R, Tompkins LS, Gillies RJ, Lynch RM. Simultaneous analysis of intracellular pH and Ca2+ from cell populations. Methods in Molecular Biology (Clifton, N.J.). 114: 287-306. PMID 10081026 DOI: 10.1385/1-59259-250-3:287  0.274
1999 Raghunand N, Altbach MI, van Sluis R, Baggett B, Taylor CW, Bhujwalla ZM, Gillies RJ. Plasmalemmal pH-gradients in drug-sensitive and drug-resistant MCF-7 human breast carcinoma xenografts measured by 31P magnetic resonance spectroscopy. Biochemical Pharmacology. 57: 309-12. PMID 9890558 DOI: 10.1016/S0006-2952(98)00306-2  0.452
1998 Bhujwalla ZM, McCoy CL, Glickson JD, Gillies RJ, Stubbs M. Estimations of intra- and extracellular volume and pH by 31P magnetic resonance spectroscopy: effect of therapy on RIF-1 tumours. British Journal of Cancer. 78: 606-11. PMID 9744499 DOI: 10.1038/Bjc.1998.548  0.41
1997 Xie X, Gillies RJ, Gerner EW. Characterization of a diamine exporter in Chinese hamster ovary cells and identification of specific polyamine substrates. The Journal of Biological Chemistry. 272: 20484-9. PMID 9252359 DOI: 10.1074/Jbc.272.33.20484  0.306
1996 Aiken NR, Gillies RJ. Phosphomonoester metabolism as a function of cell proliferative status and exogenous precursors. Anticancer Research. 16: 1393-7. PMID 8694507  0.391
1996 Martínez-Zaguilán R, Seftor EA, Seftor RE, Chu YW, Gillies RJ, Hendrix MJ. Acidic pH enhances the invasive behavior of human melanoma cells. Clinical & Experimental Metastasis. 14: 176-86. PMID 8605731 DOI: 10.1007/Bf00121214  0.347
1995 Galons J‐, Job C, Gillies RJ. Increase of GPC levels in cultured mammalian cells during acidosis. A 31P MR spectroscopy study using a continuous bioreactor system. Magnetic Resonance in Medicine. 33: 422-426. PMID 7760711 DOI: 10.1002/Mrm.1910330317  0.417
1994 Gillies RJ, Liu Z, Bhujwalla Z. 31P-MRS measurements of extracellular pH of tumors using 3-aminopropylphosphonate. The American Journal of Physiology. 267: C195-203. PMID 8048479 DOI: 10.1152/Ajpcell.1994.267.1.C195  0.496
1994 Gillies RJ, Barry JA, Ross BD. In vitro and in vivo 13C and 31P NMR analyses of phosphocholine metabolism in rat glioma cells. Magnetic Resonance in Medicine. 32: 310-8. PMID 7984063 DOI: 10.1002/Mrm.1910320306  0.452
1993 Barry JA, McGovern KA, Lien YH, Ashmore B, Gillies RJ. Dimethyl methylphosphonate (DMMP): a 31P nuclear magnetic resonance spectroscopic probe of intracellular volume in mammalian cell cultures. Biochemistry. 32: 4665-70. PMID 8485143 DOI: 10.1021/Bi00068A026  0.389
1993 Gillies RJ, Galons JP, McGovern KA, Scherer PG, Lien YH, Job C, Ratcliff R, Chapa F, Cerdan S, Dale BE. Design and application of NMR-compatible bioreactor circuits for extended perfusion of high-density mammalian cell cultures. Nmr in Biomedicine. 6: 95-104. PMID 8457432 DOI: 10.1002/nbm.1940060115  0.381
1993 Martinez-Zaguilan R, Lynch RM, Martinez GM, Gillies RJ. Vacuolar-type H(+)-ATPases are functionally expressed in plasma membranes of human tumor cells. The American Journal of Physiology. 265: C1015-29. PMID 8238296 DOI: 10.1152/Ajpcell.1993.265.4.C1015  0.312
1992 Gillies RJ. Nuclear magnetic resonance and its applications to physiological problems. Annual Review of Physiology. 54: 733-48. PMID 1562189 DOI: 10.1146/annurev.ph.54.030192.003505  0.349
1992 Lien YH, Zhou HZ, Job C, Barry JA, Gillies RJ. In vivo 31P NMR study of early cellular responses to hyperosmotic shock in cultured glioma cells. Biochimie. 74: 931-9. PMID 1467347 DOI: 10.1016/0300-9084(92)90077-R  0.425
1992 Martínez-Zaguilán R, Gillies RJ. A plasma membrane V-type H(+)-ATPase may contribute to elevated intracellular pH (pHin) in some human tumor cells. Annals of the New York Academy of Sciences. 671: 478-80. PMID 1288345 DOI: 10.1111/J.1749-6632.1992.Tb43834.X  0.412
1992 Gillies RJ, Martinez-Zaguilan R, Peterson EP, Perona R. Role of intracellular pH in mammalian cell proliferation Cellular Physiology and Biochemistry. 2: 159-179. DOI: 10.1159/000154638  0.403
1991 Gillies RJ, Scherer PG, Raghunand N, Okerlund LS, Martinez-Zaguilan R, Hesterberg L, Dale BE. Iteration of hybridoma growth and productivity in hollow fiber bioreactors using 31P NMR. Magnetic Resonance in Medicine. 18: 181-92. PMID 2062229 DOI: 10.1002/Mrm.1910180118  0.368
1991 Dale BE, Gillies RJ. Nuclear magnetic resonance spectroscopy of dense cell populations for metabolic studies and bioreactor engineering: a synergistic partnership. Biotechnology (Reading, Mass.). 17: 107-18. PMID 2049536 DOI: 10.1016/B978-0-409-90123-8.50011-2  0.387
1991 Martínez-Zaguilán R, Martínez GM, Lattanzio F, Gillies RJ. Simultaneous measurement of intracellular pH and Ca2+ using the fluorescence of SNARF-1 and fura-2. The American Journal of Physiology. 260: C297-307. PMID 1996613 DOI: 10.1152/Ajpcell.1991.260.2.C297  0.369
1991 Gillies RJ, Martinez-Zaguilan R. Regulation of intracellular pH in BALB/c 3T3 cells. Bicarbonate raises pH via NaHCO3/HCl exchange and attenuates the activation of Na+/H+ exchange by serum. The Journal of Biological Chemistry. 266: 1551-6. PMID 1846359  0.309
1990 Gillies RJ, Martinez-Zaguilan R, Martinez GM, Serrano R, Perona R. Tumorigenic 3T3 cells maintain an alkaline intracellular pH under physiological conditions. Proceedings of the National Academy of Sciences of the United States of America. 87: 7414-8. PMID 2170979 DOI: 10.1073/Pnas.87.19.7414  0.428
1989 Gillies RJ, MacKenzie NE, Dale BE. Analyses of Bioreactor Performance by Nuclear Magnetic Resonance Spectroscopy Nature Biotechnology. 7: 50-54. DOI: 10.1038/Nbt0189-50  0.312
1988 Drury DD, Dale BE, Gillies RJ. Oxygen transfer properties of a bioreactor for use within a nuclear magnetic resonance spectrometer. Biotechnology and Bioengineering. 32: 966-74. PMID 18587814 DOI: 10.1002/bit.260320804  0.393
1988 Lucas CA, Gillies RJ, Olson JE, Giuliano KA, Martinez R, Sneider JM. Intracellular acidification inhibits the proliferative response in BALB/c-3T3 cells. Journal of Cellular Physiology. 136: 161-167. PMID 3397393 DOI: 10.1002/Jcp.1041360121  0.303
1988 Martinez R, Gillies RJ, Giuliano KA. Effect of serum on the intracellular pH of BALB/c-3T3 cells: serum deprivation causes changes in sensitivity of cells to serum. Journal of Cellular Physiology. 136: 154-160. PMID 2840441 DOI: 10.1002/Jcp.1041360120  0.383
1987 Nelson TR, Gillies RJ, Powell DA, Schrader MC, Manchester DK, Pretorius DH. High resolution of proton NMR spectroscopy of human amniotic fluid Prenatal Diagnosis. 7: 363-372. PMID 3615362 DOI: 10.1002/Pd.1970070511  0.375
1987 DeFronzo M, Gillies RJ. Characterization of methylphosphonate as a 31P NMR pH indicator. The Journal of Biological Chemistry. 262: 11032-7. PMID 3611105  0.295
1987 Gillies RJ, Cook J, Fox MH, Giuliano KA. Flow cytometric analysis of intracellular pH in 3T3 cells. American Journal of Physiology-Cell Physiology. 253. PMID 3605325 DOI: 10.1152/Ajpcell.1987.253.1.C121  0.416
1987 Giuliano KA, Gillies RJ. Determination of intracellular pH of BALB/c-3T3 cells using the fluorescence of pyranine. Analytical Biochemistry. 167: 362-371. PMID 2831755 DOI: 10.1016/0003-2697(87)90178-3  0.404
1983 Findly RC, Gillies RJ, Shulman RG. In vivo phosphorus-31 nuclear magnetic resonance reveals lowered ATP during heat shock of Tetrahymena. Science (New York, N.Y.). 219: 1223-5. PMID 6828852 DOI: 10.1126/Science.6828852  0.5
1983 Gillies RJ, Benoit AG. NMR analysis of a cell division cycle mutant of Saccharomyces cerevisiae. Biochimica Et Biophysica Acta. 762: 466-470. PMID 6303444 DOI: 10.1016/0167-4889(83)90013-7  0.378
1982 Gillies RJ, Ogino T, Shulman RG, Ward DC. 31P nuclear magnetic resonance evidence for the regulation of intracellular pH by Ehrlich ascites tumor cells. The Journal of Cell Biology. 95: 24-8. PMID 7142288 DOI: 10.1083/JCB.95.1.24  0.643
1981 Alger JR, Sillerud LO, Behar KL, Gillies RJ, Shulman RG, Gordon RE, Shae D, Hanley PE. In vivo carbon-13 nuclear magnetic resonance studies of mammals. Science (New York, N.Y.). 214: 660-2. PMID 7292005 DOI: 10.1126/science.7292005  0.759
1981 Gillies RJ, Alger JR, den Hollander JA, Shulman RG. Intracellular pH measured by NMR: methods and results. Kroc Foundation Series. 15: 79-104. PMID 7042927  0.717
1981 Gillies RJ, Ugurbil K, den Hollander JA, Shulman RG. 31P NMR studies of intracellular pH and phosphate metabolism during cell division cycle of Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 78: 2125-9. PMID 7017724 DOI: 10.1073/Pnas.78.4.2125  0.739
1981 Gillies RJ, Rosenberg MP, Deamer DW. Carbon dioxide efflux accompanies release of fertilization acid from sea urchin eggs. Journal of Cellular Physiology. 108: 115-22. PMID 6790553 DOI: 10.1002/jcp.1041080202  0.654
1980 Gillies RJ, Deamer DW. Endogenously produced CO2 induces stationary phase in Tetrahymena cultures. Journal of Cellular Physiology. 105: 221-5. PMID 6780574 DOI: 10.1002/jcp.1041050205  0.668
1979 Gillies RJ, Deamer DW. Intracellular pH changes during the cell cycle in Tetrahymena. Journal of Cellular Physiology. 100: 23-31. PMID 38259 DOI: 10.1002/jcp.1041000103  0.679
1976 Noble EP, Gillies R, Vigran R, Mandel P. The modification of the ethanol withdrawal syndrome in rats by di-n-propylacetate. Psychopharmacologia. 46: 127-31. PMID 781711 DOI: 10.1007/BF00421381  0.661
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