Jennifer L. Leight, Ph.D. - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Tissue Microfabrication

27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Dedhia PH, Sivakumar H, Rodriguez MA, Nairon KG, Zent JM, Zheng X, Jones K, Popova LV, Leight JL, Skardal A. A 3D adrenocortical carcinoma tumor platform for preclinical modeling of drug response and matrix metalloproteinase activity. Scientific Reports. 13: 15508. PMID 37726363 DOI: 10.1038/s41598-023-42659-0  0.354
2023 Tahara S, de Faria FCC, Sarchet P, Calore F, Sharick J, Leight JL, Casadei L, Pollock RE. Three dimensional models of dedifferentiated liposarcoma cell lines: scaffold-based and scaffold-free approaches. Human Cell. PMID 36763259 DOI: 10.1007/s13577-023-00865-y  0.682
2023 Dedhia PH, Sivakumar H, Rodriguez MA, Nairon KG, Zent JM, Zheng X, Jones K, Popova L, Leight JL, Skardal A. A 3D adrenocortical carcinoma tumor platform for preclinical modeling of drug response and matrix metalloproteinase activity. Biorxiv : the Preprint Server For Biology. PMID 36747748 DOI: 10.1101/2023.01.24.525287  0.38
2022 Jones CE, Sharick JT, Sizemore ST, Cukierman E, Strohecker AM, Leight JL. A miniaturized screening platform to identify novel regulators of extracellular matrix alignment. Cancer Research Communications. 2: 1471-1486. PMID 36530465 DOI: 10.1158/2767-9764.CRC-22-0157  0.664
2022 Sharick JT, Atieh AJ, Gooch KJ, Leight JL. Click chemistry functionalization of self-assembling peptide hydrogels. Journal of Biomedical Materials Research. Part A. PMID 36210776 DOI: 10.1002/jbm.a.37460  0.66
2022 Nairon KG, DePalma TJ, Zent JM, Leight JL, Skardal A. Tumor cell-conditioned media drives collagen remodeling via fibroblast and pericyte activation in an premetastatic niche model. Iscience. 25: 104645. PMID 35811850 DOI: 10.1016/j.isci.2022.104645  0.363
2021 Jones CE, Sharick JT, Colbert SE, Shukla VC, Zent JM, Ostrowski MC, Ghadiali SN, Sizemore ST, Leight JL. Pten regulates collagen fibrillogenesis by fibroblasts through SPARC. Plos One. 16: e0245653. PMID 33534863 DOI: 10.1371/journal.pone.0245653  0.674
2020 Wormsbaecher C, Hindman AR, Avendano A, Cortes-Medina M, Jones CE, Bushman A, Onua L, Kovalchin CE, Murphy AR, Helber HL, Shapiro A, Voytovitch K, Kuang X, Aguilar-Valenzuela R, Leight JL, et al. In utero estrogenic endocrine disruption alters the stroma to increase extracellular matrix density and mammary gland stiffness. Breast Cancer Research : Bcr. 22: 41. PMID 32370801 DOI: 10.1186/S13058-020-01275-W  0.322
2019 Casadei L, Calore F, Braggio DA, Zewdu A, Deshmukh AA, Fadda P, Lopez G, Wabitsch M, Song C, Leight JL, Grignol VP, Lev D, Croce CM, Pollock RE. MDM2 derived from dedifferentiated liposarcoma extracellular vesicles induces MMP2 production from preadipocytes. Cancer Research. PMID 31387924 DOI: 10.1158/0008-5472.Can-19-0203  0.397
2019 Campbell WA, Deshmukh A, Blum S, Todd L, Mendonca N, Weist J, Zent J, Hoang TV, Blackshaw S, Leight J, Fischer AJ. Matrix-metalloproteinase expression and gelatinase activity in the avian retina and their influence on Müller glia proliferation. Experimental Neurology. 112984. PMID 31251936 DOI: 10.1016/J.Expneurol.2019.112984  0.397
2019 Fakhouri AS, Weist JL, Tomusko AR, Leight JL. High-Throughput Three-Dimensional Hydrogel Cell Encapsulation Assay for Measuring Matrix Metalloproteinase Activity. Assay and Drug Development Technologies. 17: 100-115. PMID 30958702 DOI: 10.1089/Adt.2018.877  0.446
2019 Fakhouri AS, Leight JL. Measuring Global Cellular Matrix Metalloproteinase and Metabolic Activity in 3D Hydrogels. Journal of Visualized Experiments : Jove. PMID 30735180 DOI: 10.3791/59123  0.461
2019 Casadei L, Calore F, Deshmukh A, Zewdu A, Braggio DA, Fadda P, Wabitsch M, Lopez G, Leight J, Lev D, Croce CM, Pollock RE. Abstract 1891: OncogenicMDM2-containing exosomes promote pre-metastatic niche establishment Cancer Research. 79: 1891-1891. DOI: 10.1158/1538-7445.Am2019-1891  0.359
2018 Jones CE, Hammer AM, Cho Y, Sizemore GM, Cukierman E, Yee LD, Ghadiali SN, Ostrowski MC, Leight JL. Stromal PTEN Regulates Extracellular Matrix Organization in the Mammary Gland. Neoplasia (New York, N.Y.). 21: 132-145. PMID 30550871 DOI: 10.1016/J.Neo.2018.10.010  0.476
2018 Deshmukh AA, Weist JL, Leight JL. Detection of proteolytic activity by covalent tethering of fluorogenic substrates in zymogram gels. Biotechniques. 64: 203-210. PMID 29793363 DOI: 10.2144/Btn-2018-0005  0.354
2018 Barnhouse VR, Weist JL, Shukla VC, Ghadiali SN, Kniss DA, Leight JL. Myoferlin regulates epithelial cancer cell plasticity and migration through autocrine TGF-β1 signaling. Oncotarget. 9: 19209-19222. PMID 29721195 DOI: 10.18632/Oncotarget.24971  0.32
2018 Shin DS, Tokuda EY, Leight JL, Miksch CE, Brown TE, Anseth KS. Synthesis of microgel sensors for spatial and temporal monitoring of protease activity. Acs Biomaterials Science & Engineering. 4: 378-387. PMID 29527570 DOI: 10.1021/Acsbiomaterials.7B00017  0.391
2017 Shukla V, Barnhouse V, Ackerman WE, Summerfield TL, Powell HM, Leight JL, Kniss DA, Ghadiali SN. Cellular Mechanics of Primary Human Cervical Fibroblasts: Influence of Progesterone and a Pro-inflammatory Cytokine. Annals of Biomedical Engineering. PMID 28939933 DOI: 10.1007/S10439-017-1935-0  0.371
2015 Leight JL, Tokuda EY, Jones CE, Lin AJ, Anseth KS. Multifunctional bioscaffolds for 3D culture of melanoma cells reveal increased MMP activity and migration with BRAF kinase inhibition. Proceedings of the National Academy of Sciences of the United States of America. 112: 5366-71. PMID 25870264 DOI: 10.1073/Pnas.1505662112  0.409
2015 Sridhar BV, Brock JL, Silver JS, Leight JL, Randolph MA, Anseth KS. Tissue engineering: development of a cellularly degradable PEG hydrogel to promote articular cartilage extracellular matrix deposition (adv. Healthcare mater. 5/2015). Advanced Healthcare Materials. 4: 635. PMID 25851274 DOI: 10.1002/Adhm.201570027  0.383
2015 Sridhar BV, Brock JL, Silver JS, Leight JL, Randolph MA, Anseth KS. Development of a cellularly degradable PEG hydrogel to promote articular cartilage extracellular matrix deposition. Advanced Healthcare Materials. 4: 702-13. PMID 25607633 DOI: 10.1002/Adhm.201400695  0.488
2014 Tokuda EY, Leight JL, Anseth KS. Modulation of matrix elasticity with PEG hydrogels to study melanoma drug responsiveness. Biomaterials. 35: 4310-8. PMID 24565518 DOI: 10.1016/J.Biomaterials.2014.01.063  0.43
2013 Leight JL, Alge DL, Maier AJ, Anseth KS. Direct measurement of matrix metalloproteinase activity in 3D cellular microenvironments using a fluorogenic peptide substrate. Biomaterials. 34: 7344-52. PMID 23830581 DOI: 10.1016/J.Biomaterials.2013.06.023  0.476
2012 Leight JL, Liu WF, Chaturvedi RR, Chen S, Yang MT, Raghavan S, Chen CS. Manipulation of 3D Cluster Size and Geometry by Release from 2D Micropatterns. Cellular and Molecular Bioengineering. 5: 299-306. PMID 23730348 DOI: 10.1007/S12195-012-0236-9  0.582
2012 Leight JL, Wozniak MA, Chen S, Lynch ML, Chen CS. Matrix rigidity regulates a switch between TGF-β1-induced apoptosis and epithelial-mesenchymal transition. Molecular Biology of the Cell. 23: 781-91. PMID 22238361 DOI: 10.1091/Mbc.E11-06-0537  0.51
2009 Gehler S, Baldassarre M, Lad Y, Leight JL, Wozniak MA, Riching KM, Eliceiri KW, Weaver VM, Calderwood DA, Keely PJ. Filamin A-beta1 integrin complex tunes epithelial cell response to matrix tension. Molecular Biology of the Cell. 20: 3224-38. PMID 19458194 DOI: 10.1091/Mbc.E08-12-1186  0.473
2007 Johnson KR, Leight JL, Weaver VM. Demystifying the effects of a three-dimensional microenvironment in tissue morphogenesis. Methods in Cell Biology. 83: 547-83. PMID 17613324 DOI: 10.1016/S0091-679X(07)83023-8  0.408
Show low-probability matches.