Year |
Citation |
Score |
2024 |
Wang X, Jing X, Shi J, Liu Q, Shen S, Cheung PP, Wu J, Deng F, Gong P. A jingmenvirus RNA-dependent RNA polymerase structurally resembles the flavivirus counterpart but with different features at the initiation phase. Nucleic Acids Research. PMID 38296832 DOI: 10.1093/nar/gkae042 |
0.386 |
|
2023 |
Tan Z, Wu J, Huang L, Wang T, Zheng Z, Zhang J, Ke X, Zhang Y, Liu Y, Wang H, Tao J, Gong P. LGP2 directly interacts with flavivirus NS5 RNA-dependent RNA polymerase and downregulates its pre-elongation activities. Plos Pathogens. 19: e1011620. PMID 37656756 DOI: 10.1371/journal.ppat.1011620 |
0.389 |
|
2023 |
Fang X, Lu G, Deng Y, Yang S, Hou C, Gong P. Unusual substructure conformations observed in crystal structures of a dicistrovirus RNA-dependent RNA polymerase suggest contribution of the N-terminal extension in proper folding. Virologica Sinica. PMID 37156298 DOI: 10.1016/j.virs.2023.05.002 |
0.332 |
|
2022 |
Wu J, Wang X, Liu Q, Lu G, Gong P. Structural basis of transition from initiation to elongation in de novo viral RNA-dependent RNA polymerases. Proceedings of the National Academy of Sciences of the United States of America. 120: e2211425120. PMID 36577062 DOI: 10.1073/pnas.2211425120 |
0.433 |
|
2022 |
Li R, Wang M, Gong P. Crystal structure of a pre-chemistry viral RNA-dependent RNA polymerase suggests participation of two basic residues in catalysis. Nucleic Acids Research. PMID 36477355 DOI: 10.1093/nar/gkac1133 |
0.309 |
|
2022 |
Chen S, Wu J, Yang X, Sun Q, Liu S, Rashid F, Dzakah EE, Wang H, Wang J, Gong P, Tang S. RNA-Dependent RNA Polymerase of the Second Human Pegivirus Exhibits a High-Fidelity Feature. Microbiology Spectrum. e0272922. PMID 35980196 DOI: 10.1128/spectrum.02729-22 |
0.319 |
|
2022 |
Hao H, Liu W, Miao Y, Ma L, Yu B, Liu L, Yang C, Zhang K, Chen Z, Yang J, Zheng Z, Zhang B, Deng F, Gong P, Yuan J, et al. N4-acetylcytidine regulates the replication and pathogenicity of enterovirus 71. Nucleic Acids Research. PMID 35971620 DOI: 10.1093/nar/gkac675 |
0.416 |
|
2022 |
Liu Q, Wu J, Gong P. Assessment of nucleotide/nucleoside analog intervention in primer-dependent viral RNA-dependent RNA polymerases. Star Protocols. 3: 101468. PMID 35761985 DOI: 10.1016/j.xpro.2022.101468 |
0.351 |
|
2022 |
Jia H, Zhong Y, Peng C, Gong P. Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct. Journal of Virology. e0041822. PMID 35758665 DOI: 10.1128/jvi.00418-22 |
0.366 |
|
2021 |
Gong P. Within and Beyond the Nucleotide Addition Cycle of Viral RNA-dependent RNA Polymerases. Frontiers in Molecular Biosciences. 8: 822218. PMID 35083282 DOI: 10.3389/fmolb.2021.822218 |
0.432 |
|
2021 |
Gong P. Structural basis of viral RNA-dependent RNA polymerase nucleotide addition cycle in picornaviruses. The Enzymes. 49: 215-233. PMID 34696833 DOI: 10.1016/bs.enz.2021.06.002 |
0.452 |
|
2021 |
Wu J, Wang H, Liu Q, Li R, Gao Y, Fang X, Zhong Y, Wang M, Wang Q, Rao Z, Gong P. Remdesivir overcomes the S861 roadblock in SARS-CoV-2 polymerase elongation complex. Cell Reports. 109882. PMID 34653416 DOI: 10.1016/j.celrep.2021.109882 |
0.373 |
|
2021 |
Zhang BY, Liu W, Jia H, Lu G, Gong P. An induced-fit de novo initiation mechanism suggested by a pestivirus RNA-dependent RNA polymerase. Nucleic Acids Research. PMID 34365500 DOI: 10.1093/nar/gkab666 |
0.44 |
|
2021 |
Yang J, Jing X, Yi W, Li XD, Yao C, Zhang B, Zheng Z, Wang H, Gong P. Crystal structure of a tick-borne flavivirus RNA-dependent RNA polymerase suggests a host adaptation hotspot in RNA viruses. Nucleic Acids Research. PMID 33406260 DOI: 10.1093/nar/gkaa1250 |
0.347 |
|
2020 |
Wu L, Jin D, Wang D, Jing X, Gong P, Qin Y, Chen M. The two-stage interaction of Ebola virus VP40 with nucleoprotein results in a switch from viral RNA synthesis to virion assembly/budding. Protein & Cell. PMID 33141416 DOI: 10.1007/s13238-020-00764-0 |
0.305 |
|
2020 |
Wang Q, Wu J, Wang H, Gao Y, Liu Q, Mu A, Ji W, Yan L, Zhu Y, Zhu C, Fang X, Yang X, Huang Y, Gao H, Liu F, ... ... Gong P, et al. Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase. Cell. PMID 32526208 DOI: 10.1016/J.Cell.2020.05.034 |
0.519 |
|
2020 |
Wang M, Li R, Shu B, Jing X, Ye HQ, Gong P. Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures. Nature Communications. 11: 2605. PMID 32451382 DOI: 10.1038/s41467-020-16234-4 |
0.442 |
|
2020 |
Wu J, Ye HQ, Zhang QY, Lu G, Zhang B, Gong P. A conformation-based intra-molecular initiation factor identified in the flavivirus RNA-dependent RNA polymerase. Plos Pathogens. 16: e1008484. PMID 32357182 DOI: 10.1371/Journal.Ppat.1008484 |
0.304 |
|
2020 |
Zhang QY, Li XF, Niu X, Li N, Wang HJ, Deng CL, Ye HQ, Huang XY, Chen Q, Xu YP, Dong HL, Li XD, Zhao H, Shi PY, Yuan ZM, ... Gong P, et al. Short direct repeats in the 3'-untranslated region are involved in subgenomic flaviviral RNA production. Journal of Virology. PMID 31896596 DOI: 10.1128/Jvi.01175-19 |
0.411 |
|
2019 |
Shi W, Ye HQ, Deng CL, Li R, Zhang B, Gong P. A nucleobase-binding pocket in a viral RNA-dependent RNA polymerase contributes to elongation complex stability. Nucleic Acids Research. PMID 31863580 DOI: 10.1093/Nar/Gkz1170 |
0.417 |
|
2019 |
Jia H, Gong P. A Structure-Function Diversity Survey of the RNA-Dependent RNA Polymerases From the Positive-Strand RNA Viruses. Frontiers in Microbiology. 10: 1945. PMID 31507560 DOI: 10.3389/fmicb.2019.01945 |
0.4 |
|
2018 |
Liu W, Shi X, Gong P. A unique intra-molecular fidelity-modulating mechanism identified in a viral RNA-dependent RNA polymerase. Nucleic Acids Research. PMID 30239956 DOI: 10.1093/nar/gky848 |
0.41 |
|
2018 |
Zheng Z, Yang J, Jiang X, Liu Y, Zhang X, Li M, Zhang M, Fu M, Hu K, Wang H, Luo MH, Gong P, Hu Q. Tick-Borne Encephalitis Virus Nonstructural Protein NS5 Induces RANTES Expression Dependent on the RNA-Dependent RNA Polymerase Activity. Journal of Immunology (Baltimore, Md. : 1950). PMID 29760190 DOI: 10.4049/Jimmunol.1701507 |
0.427 |
|
2018 |
Wu J, Gong P. Visualizing the Nucleotide Addition Cycle of Viral RNA-Dependent RNA Polymerase. Viruses. 10. PMID 29300357 DOI: 10.3390/v10010024 |
0.407 |
|
2017 |
Bi P, Shu B, Gong P. Crystal structure of the coxsackievirus A16 RNA-dependent RNA polymerase elongation complex reveals novel features in motif A dynamics. Virologica Sinica. PMID 29164396 DOI: 10.1007/s12250-017-4066-8 |
0.397 |
|
2017 |
Zheng F, Lu G, Li L, Gong P, Pan Z. The uncoupling of protease trans-cleavage and helicase activities in the pestivirus NS3. Journal of Virology. PMID 28835495 DOI: 10.1128/JVI.01094-17 |
0.323 |
|
2017 |
Shi W, Gong P. A practical approach to generate suitable de novo synthesis RNA template for a flavivirus RNA-dependent RNA polymerase. Virologica Sinica. PMID 28646484 DOI: 10.1007/s12250-017-4003-x |
0.405 |
|
2017 |
Shu B, Gong P. The uncoupling of catalysis and translocation in the viral RNA-dependent RNA polymerase. Rna Biology. 0. PMID 28277928 DOI: 10.1080/15476286.2017.1300221 |
0.453 |
|
2017 |
Lu G, Gong P. A structural view of the RNA-dependent RNA polymerases from the Flavivirus genus. Virus Research. PMID 28131854 DOI: 10.1016/J.Virusres.2017.01.020 |
0.512 |
|
2016 |
Liu Y, Zheng Z, Shu B, Meng J, Zhang Y, Zheng C, Ke X, Gong P, Hu Q, Wang H. SUMO Modification Stabilizes Enterovirus 71 Polymerase 3D to Facilitate Viral Replication. Journal of Virology. PMID 27630238 DOI: 10.1128/Jvi.01756-16 |
0.384 |
|
2016 |
Wang SR, Zhang QY, Wang JQ, Ge XY, Song YY, Wang YF, Li XD, Fu BS, Xu GH, Shu B, Gong P, Zhang B, Tian T, Zhou X. Chemical Targeting of a G-Quadruplex RNA in the Ebola Virus L Gene. Cell Chemical Biology. PMID 27617851 DOI: 10.1016/J.Chembiol.2016.07.019 |
0.435 |
|
2016 |
Shu B, Gong P. Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation. Proceedings of the National Academy of Sciences of the United States of America. PMID 27339134 DOI: 10.1073/Pnas.1602591113 |
0.512 |
|
2015 |
Wu J, Liu W, Gong P. A Structural Overview of RNA-Dependent RNA Polymerases from the Flaviviridae Family. International Journal of Molecular Sciences. 16: 12943-12957. PMID 26062131 DOI: 10.3390/ijms160612943 |
0.449 |
|
2015 |
Chen L, Yan Q, Lu G, Hu Z, Zhang G, Zhang S, Ding B, Jiang Y, Zhong Y, Gong P, Chen M. Several residues within the N-terminal arm of vesicular stomatitis virus nucleoprotein play a critical role in protecting viral RNA from nuclease digestion. Virology. 478: 9-17. PMID 25682471 DOI: 10.1016/j.virol.2015.01.021 |
0.357 |
|
2015 |
Wu J, Lu G, Zhang B, Gong P. Perturbation in the conserved methyltransferase-polymerase interface of flavivirus NS5 differentially affects polymerase initiation and elongation. Journal of Virology. 89: 249-61. PMID 25320292 DOI: 10.1128/Jvi.02085-14 |
0.517 |
|
2014 |
Shang L, Wang Y, Qing J, Shu B, Cao L, Lou Z, Gong P, Sun Y, Yin Z. An adenosine nucleoside analogue NITD008 inhibits EV71 proliferation. Antiviral Research. 112: 47-58. PMID 25446894 DOI: 10.1016/J.Antiviral.2014.10.009 |
0.382 |
|
2014 |
Li XD, Shan C, Deng CL, Ye HQ, Shi PY, Yuan ZM, Gong P, Zhang B. The interface between methyltransferase and polymerase of NS5 is essential for flavivirus replication. Plos Neglected Tropical Diseases. 8: e2891. PMID 24852307 DOI: 10.1371/Journal.Pntd.0002891 |
0.446 |
|
2014 |
Deng Z, Lehmann KC, Li X, Feng C, Wang G, Zhang Q, Qi X, Yu L, Zhang X, Feng W, Wu W, Gong P, Tao Y, Posthuma CC, Snijder EJ, et al. Structural basis for the regulatory function of a complex zinc-binding domain in a replicative arterivirus helicase resembling a nonsense-mediated mRNA decay helicase. Nucleic Acids Research. 42: 3464-77. PMID 24369429 DOI: 10.1093/Nar/Gkt1310 |
0.39 |
|
2013 |
Lu G, Gong P. Crystal Structure of the full-length Japanese encephalitis virus NS5 reveals a conserved methyltransferase-polymerase interface. Plos Pathogens. 9: e1003549. PMID 23950717 DOI: 10.1371/Journal.Ppat.1003549 |
0.446 |
|
2013 |
Gong P, Kortus MG, Nix JC, Davis RE, Peersen OB. Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts. Plos One. 8: e60272. PMID 23667424 DOI: 10.1371/Journal.Pone.0060272 |
0.527 |
|
2012 |
Gnädig NF, Beaucourt S, Campagnola G, Bordería AV, Sanz-Ramos M, Gong P, Blanc H, Peersen OB, Vignuzzi M. Coxsackievirus B3 mutator strains are attenuated in vivo. Proceedings of the National Academy of Sciences of the United States of America. 109: E2294-303. PMID 22853955 DOI: 10.1073/Pnas.1204022109 |
0.355 |
|
2011 |
Campagnola G, Gong P, Peersen OB. High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors. Antiviral Research. 91: 241-51. PMID 21722674 DOI: 10.1016/J.Antiviral.2011.06.006 |
0.503 |
|
2010 |
Gong P, Peersen OB. Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase. Proceedings of the National Academy of Sciences of the United States of America. 107: 22505-10. PMID 21148772 DOI: 10.1073/Pnas.1007626107 |
0.518 |
|
2009 |
Murphy MN, Gong P, Ralto K, Manelyte L, Savery NJ, Theis K. An N-terminal clamp restrains the motor domains of the bacterial transcription-repair coupling factor Mfd. Nucleic Acids Research. 37: 6042-53. PMID 19700770 DOI: 10.1093/Nar/Gkp680 |
0.325 |
|
2009 |
Gong P, Campagnola G, Peersen OB. A quantitative stopped-flow fluorescence assay for measuring polymerase elongation rates. Analytical Biochemistry. 391: 45-55. PMID 19406094 DOI: 10.1016/J.Ab.2009.04.035 |
0.404 |
|
2006 |
Gong P, Martin CT. Mechanism of instability in abortive cycling by T7 RNA polymerase. The Journal of Biological Chemistry. 281: 23533-44. PMID 16790422 DOI: 10.1074/Jbc.M604023200 |
0.657 |
|
2005 |
Martin CT, Esposito EA, Theis K, Gong P. Structure and function in promoter escape by T7 RNA polymerase. Progress in Nucleic Acid Research and Molecular Biology. 80: 323-47. PMID 16164978 DOI: 10.1016/S0079-6603(05)80008-X |
0.704 |
|
2004 |
Theis K, Gong P, Martin CT. Topological and conformational analysis of the initiation and elongation complex of t7 RNA polymerase suggests a new twist. Biochemistry. 43: 12709-15. PMID 15461442 DOI: 10.1021/Bi0486987 |
0.576 |
|
2004 |
Gong P, Esposito EA, Martin CT. Initial bubble collapse plays a key role in the transition to elongation in T7 RNA polymerase. The Journal of Biological Chemistry. 279: 44277-85. PMID 15337752 DOI: 10.1074/Jbc.M409118200 |
0.702 |
|
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