Selwyn S. Jayakar, Ph.D. - Publications

Institution:
The University of Toledo
Area:
nicotinic receptors, neuropeptides

21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 McGrath M, Hoyt H, Pence A, Jayakar SS, Zhou X, Forman SA, Cohen JB, Miller KW, Raines DE. Competitive Antagonism of Etomidate Action by Diazepam: In Vitro GABAA Receptor and In Vivo Zebrafish Studies. Anesthesiology. PMID 32541553 DOI: 10.1097/Aln.0000000000003403  0.376
2020 Jayakar SS, Chiara DC, Zhou X, Wu B, Bruzik KS, Miller KW, Cohen JB. Photoaffinity labeling identifies an intersubunit steroid-binding site in heteromeric GABA type A (GABA) receptors. The Journal of Biological Chemistry. PMID 32540960 DOI: 10.1074/Jbc.Ra120.013452  0.368
2018 Wu B, Jayakar SS, Zhou X, Titterton K, Chiara DC, Szabo AL, Savechenkov PY, Kent DE, Cohen JB, Forman SA, Miller KW, Bruzik KS. Inhibitable photolabeling by neurosteroid diazirine analog in the β3-Subunit of human hetereopentameric type A GABA receptors. European Journal of Medicinal Chemistry. 162: 810-824. PMID 30544077 DOI: 10.1016/J.Ejmech.2018.11.019  0.391
2018 McGrath M, Yu Z, Jayakar SS, Ma C, Tolia M, Zhou X, Miller KW, Cohen JB, Raines DE. Etomidate and Etomidate Analog Binding and Positive Modulation of γ-Aminobutyric Acid Type A Receptors: Evidence for a State-dependent Cutoff Effect. Anesthesiology. PMID 30052529 DOI: 10.1097/Aln.0000000000002356  0.35
2017 Ma C, Pejo E, McGrath M, Jayakar SS, Zhou X, Miller KW, Cohen JB, Raines DE. Competitive Antagonism of Anesthetic Action at the γ-Aminobutyric Acid Type A Receptor by a Novel Etomidate Analog with Low Intrinsic Efficacy. Anesthesiology. PMID 28857763 DOI: 10.1097/Aln.0000000000001840  0.336
2017 Jayakar SS, Ang G, Chiara DC, Hamouda AK. Photoaffinity Labeling of Pentameric Ligand-Gated Ion Channels: A Proteomic Approach to Identify Allosteric Modulator Binding Sites. Methods in Molecular Biology (Clifton, N.J.). 1598: 157-197. PMID 28508361 DOI: 10.1007/978-1-4939-6952-4_7  0.307
2016 Jayakar SS, Zhou X, Savechenkov PY, Bruzik KS, Miller KW, Cohen JB. Identifying GABA-A Receptor Modulators that Bind to Intersubunit Sites in the GABA-A Receptor Transmembrane Domain Biophysical Journal. 110: 454a-455a. DOI: 10.1016/J.Bpj.2015.11.2437  0.366
2015 Mohamed TS, Jayakar SS, Hamouda AK. Orthosteric and Allosteric Ligands of Nicotinic Acetylcholine Receptors for Smoking Cessation. Frontiers in Molecular Neuroscience. 8: 71. PMID 26635524 DOI: 10.3389/Fnmol.2015.00071  0.405
2015 Jayakar SS, Zhou X, Savechenkov PY, Chiara DC, Desai R, Bruzik KS, Miller KW, Cohen JB. Positive and Negative Allosteric Modulation of an α1β3γ2 γ-Aminobutyric acid Type A (GABAA) Receptor by Binding to a Site in the Transmembrane Domain at the γ+-β- Interface. The Journal of Biological Chemistry. PMID 26229099 DOI: 10.1074/Jbc.M115.672006  0.367
2014 Jayakar SS, Pugh PC, Dale Z, Starr ER, Cole S, Margiotta JF. PACAP induces plasticity at autonomic synapses by nAChR-dependent NOS1 activation and AKAP-mediated PKA targeting. Molecular and Cellular Neurosciences. 63: 1-12. PMID 25168001 DOI: 10.1016/J.Mcn.2014.08.007  0.681
2014 Jayakar SS, Zhou X, Chiara DC, Dostalova Z, Savechenkov PY, Bruzik KS, Dailey WP, Miller KW, Eckenhoff RG, Cohen JB. Multiple propofol-binding sites in a γ-aminobutyric acid type A receptor (GABAAR) identified using a photoreactive propofol analog. The Journal of Biological Chemistry. 289: 27456-68. PMID 25086038 DOI: 10.1074/Jbc.M114.581728  0.346
2014 Hamouda AK, Jayakar SS, Chiara DC, Cohen JB. Photoaffinity labeling of nicotinic receptors: diversity of drug binding sites! Journal of Molecular Neuroscience : Mn. 53: 480-6. PMID 24158732 DOI: 10.1007/S12031-013-0150-1  0.372
2013 Chiara DC, Jayakar SS, Zhou X, Zhang X, Savechenkov PY, Bruzik KS, Miller KW, Cohen JB. Specificity of intersubunit general anesthetic-binding sites in the transmembrane domain of the human α1β3γ2 γ-aminobutyric acid type A (GABAA) receptor. The Journal of Biological Chemistry. 288: 19343-57. PMID 23677991 DOI: 10.1074/Jbc.M113.479725  0.384
2013 Jayakar SS, Dailey WP, Eckenhoff RG, Cohen JB. Identification of propofol binding sites in a nicotinic acetylcholine receptor with a photoreactive propofol analog. The Journal of Biological Chemistry. 288: 6178-89. PMID 23300078 DOI: 10.1074/Jbc.M112.435909  0.379
2013 Jayakar SS, Zhou X, Dostalova Z, Dailey WP, Miller KW, Eckenhoff RG, Cohen JB. Identifying the Propofol Binding Site(S) in Heterologously Expressed Human Alpha1 Beta3 Gaba-A Receptors using a Photoreactive Propofol Analog Biophysical Journal. 104: 637a. DOI: 10.1016/J.Bpj.2012.11.3519  0.336
2012 Chiara DC, Dostalova Z, Jayakar SS, Zhou X, Miller KW, Cohen JB. Mapping general anesthetic binding site(s) in human α1β3 γ-aminobutyric acid type A receptors with [³H]TDBzl-etomidate, a photoreactive etomidate analogue. Biochemistry. 51: 836-47. PMID 22243422 DOI: 10.1021/Bi201772M  0.324
2011 Jayakar SS, Margiotta JF. Abelson family tyrosine kinases regulate the function of nicotinic acetylcholine receptors and nicotinic synapses on autonomic neurons. Molecular Pharmacology. 80: 97-109. PMID 21502378 DOI: 10.1124/Mol.111.071308  0.738
2011 Jayakar∗ SS, Dostalova Z, Chiara DC, Zhou X, Liu A, Miller KW, Cohen JB. Identifying an Etomidate Binding Site in Heterologously Expressed Human Alpha1/Beta3 GABAA Receptors (GABAAR) Using Photoactive Etomidate Analogs Biophysical Journal. 100: 271a. DOI: 10.1016/J.Bpj.2010.12.1689  0.346
2010 Pugh PC, Jayakar SS, Margiotta JF. PACAP/PAC1R signaling modulates acetylcholine release at neuronal nicotinic synapses. Molecular and Cellular Neurosciences. 43: 244-57. PMID 19958833 DOI: 10.1016/J.Mcn.2009.11.007  0.676
2006 Pugh PC, Zhou X, Jayakar SS, Margiotta JF. Depolarization promotes survival of ciliary ganglion neurons by BDNF-dependent and -independent mechanisms. Developmental Biology. 291: 182-91. PMID 16426601 DOI: 10.1016/J.Ydbio.2005.12.008  0.646
2004 Jayakar SS, Dikshit M. AMPA receptor regulation mechanisms: future target for safer neuroprotective drugs. The International Journal of Neuroscience. 114: 695-734. PMID 15204061 DOI: 10.1080/00207450490430453  0.452
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