Year |
Citation |
Score |
2020 |
McGrath M, Hoyt H, Pence A, Jayakar SS, Zhou X, Forman SA, Cohen JB, Miller KW, Raines DE. Competitive Antagonism of Etomidate Action by Diazepam: In Vitro GABAA Receptor and In Vivo Zebrafish Studies. Anesthesiology. PMID 32541553 DOI: 10.1097/Aln.0000000000003403 |
0.376 |
|
2020 |
Jayakar SS, Chiara DC, Zhou X, Wu B, Bruzik KS, Miller KW, Cohen JB. Photoaffinity labeling identifies an intersubunit steroid-binding site in heteromeric GABA type A (GABA) receptors. The Journal of Biological Chemistry. PMID 32540960 DOI: 10.1074/Jbc.Ra120.013452 |
0.368 |
|
2018 |
Wu B, Jayakar SS, Zhou X, Titterton K, Chiara DC, Szabo AL, Savechenkov PY, Kent DE, Cohen JB, Forman SA, Miller KW, Bruzik KS. Inhibitable photolabeling by neurosteroid diazirine analog in the β3-Subunit of human hetereopentameric type A GABA receptors. European Journal of Medicinal Chemistry. 162: 810-824. PMID 30544077 DOI: 10.1016/J.Ejmech.2018.11.019 |
0.391 |
|
2018 |
McGrath M, Yu Z, Jayakar SS, Ma C, Tolia M, Zhou X, Miller KW, Cohen JB, Raines DE. Etomidate and Etomidate Analog Binding and Positive Modulation of γ-Aminobutyric Acid Type A Receptors: Evidence for a State-dependent Cutoff Effect. Anesthesiology. PMID 30052529 DOI: 10.1097/Aln.0000000000002356 |
0.35 |
|
2017 |
Ma C, Pejo E, McGrath M, Jayakar SS, Zhou X, Miller KW, Cohen JB, Raines DE. Competitive Antagonism of Anesthetic Action at the γ-Aminobutyric Acid Type A Receptor by a Novel Etomidate Analog with Low Intrinsic Efficacy. Anesthesiology. PMID 28857763 DOI: 10.1097/Aln.0000000000001840 |
0.336 |
|
2017 |
Jayakar SS, Ang G, Chiara DC, Hamouda AK. Photoaffinity Labeling of Pentameric Ligand-Gated Ion Channels: A Proteomic Approach to Identify Allosteric Modulator Binding Sites. Methods in Molecular Biology (Clifton, N.J.). 1598: 157-197. PMID 28508361 DOI: 10.1007/978-1-4939-6952-4_7 |
0.307 |
|
2016 |
Jayakar SS, Zhou X, Savechenkov PY, Bruzik KS, Miller KW, Cohen JB. Identifying GABA-A Receptor Modulators that Bind to Intersubunit Sites in the GABA-A Receptor Transmembrane Domain Biophysical Journal. 110: 454a-455a. DOI: 10.1016/J.Bpj.2015.11.2437 |
0.366 |
|
2015 |
Mohamed TS, Jayakar SS, Hamouda AK. Orthosteric and Allosteric Ligands of Nicotinic Acetylcholine Receptors for Smoking Cessation. Frontiers in Molecular Neuroscience. 8: 71. PMID 26635524 DOI: 10.3389/Fnmol.2015.00071 |
0.405 |
|
2015 |
Jayakar SS, Zhou X, Savechenkov PY, Chiara DC, Desai R, Bruzik KS, Miller KW, Cohen JB. Positive and Negative Allosteric Modulation of an α1β3γ2 γ-Aminobutyric acid Type A (GABAA) Receptor by Binding to a Site in the Transmembrane Domain at the γ+-β- Interface. The Journal of Biological Chemistry. PMID 26229099 DOI: 10.1074/Jbc.M115.672006 |
0.367 |
|
2014 |
Jayakar SS, Pugh PC, Dale Z, Starr ER, Cole S, Margiotta JF. PACAP induces plasticity at autonomic synapses by nAChR-dependent NOS1 activation and AKAP-mediated PKA targeting. Molecular and Cellular Neurosciences. 63: 1-12. PMID 25168001 DOI: 10.1016/J.Mcn.2014.08.007 |
0.681 |
|
2014 |
Jayakar SS, Zhou X, Chiara DC, Dostalova Z, Savechenkov PY, Bruzik KS, Dailey WP, Miller KW, Eckenhoff RG, Cohen JB. Multiple propofol-binding sites in a γ-aminobutyric acid type A receptor (GABAAR) identified using a photoreactive propofol analog. The Journal of Biological Chemistry. 289: 27456-68. PMID 25086038 DOI: 10.1074/Jbc.M114.581728 |
0.346 |
|
2014 |
Hamouda AK, Jayakar SS, Chiara DC, Cohen JB. Photoaffinity labeling of nicotinic receptors: diversity of drug binding sites! Journal of Molecular Neuroscience : Mn. 53: 480-6. PMID 24158732 DOI: 10.1007/S12031-013-0150-1 |
0.372 |
|
2013 |
Chiara DC, Jayakar SS, Zhou X, Zhang X, Savechenkov PY, Bruzik KS, Miller KW, Cohen JB. Specificity of intersubunit general anesthetic-binding sites in the transmembrane domain of the human α1β3γ2 γ-aminobutyric acid type A (GABAA) receptor. The Journal of Biological Chemistry. 288: 19343-57. PMID 23677991 DOI: 10.1074/Jbc.M113.479725 |
0.384 |
|
2013 |
Jayakar SS, Dailey WP, Eckenhoff RG, Cohen JB. Identification of propofol binding sites in a nicotinic acetylcholine receptor with a photoreactive propofol analog. The Journal of Biological Chemistry. 288: 6178-89. PMID 23300078 DOI: 10.1074/Jbc.M112.435909 |
0.379 |
|
2013 |
Jayakar SS, Zhou X, Dostalova Z, Dailey WP, Miller KW, Eckenhoff RG, Cohen JB. Identifying the Propofol Binding Site(S) in Heterologously Expressed Human Alpha1 Beta3 Gaba-A Receptors using a Photoreactive Propofol Analog Biophysical Journal. 104: 637a. DOI: 10.1016/J.Bpj.2012.11.3519 |
0.336 |
|
2012 |
Chiara DC, Dostalova Z, Jayakar SS, Zhou X, Miller KW, Cohen JB. Mapping general anesthetic binding site(s) in human α1β3 γ-aminobutyric acid type A receptors with [³H]TDBzl-etomidate, a photoreactive etomidate analogue. Biochemistry. 51: 836-47. PMID 22243422 DOI: 10.1021/Bi201772M |
0.324 |
|
2011 |
Jayakar SS, Margiotta JF. Abelson family tyrosine kinases regulate the function of nicotinic acetylcholine receptors and nicotinic synapses on autonomic neurons. Molecular Pharmacology. 80: 97-109. PMID 21502378 DOI: 10.1124/Mol.111.071308 |
0.738 |
|
2011 |
Jayakar∗ SS, Dostalova Z, Chiara DC, Zhou X, Liu A, Miller KW, Cohen JB. Identifying an Etomidate Binding Site in Heterologously Expressed Human Alpha1/Beta3 GABAA Receptors (GABAAR) Using Photoactive Etomidate Analogs Biophysical Journal. 100: 271a. DOI: 10.1016/J.Bpj.2010.12.1689 |
0.346 |
|
2010 |
Pugh PC, Jayakar SS, Margiotta JF. PACAP/PAC1R signaling modulates acetylcholine release at neuronal nicotinic synapses. Molecular and Cellular Neurosciences. 43: 244-57. PMID 19958833 DOI: 10.1016/J.Mcn.2009.11.007 |
0.676 |
|
2006 |
Pugh PC, Zhou X, Jayakar SS, Margiotta JF. Depolarization promotes survival of ciliary ganglion neurons by BDNF-dependent and -independent mechanisms. Developmental Biology. 291: 182-91. PMID 16426601 DOI: 10.1016/J.Ydbio.2005.12.008 |
0.646 |
|
2004 |
Jayakar SS, Dikshit M. AMPA receptor regulation mechanisms: future target for safer neuroprotective drugs. The International Journal of Neuroscience. 114: 695-734. PMID 15204061 DOI: 10.1080/00207450490430453 |
0.452 |
|
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