| Year |
Citation |
Score |
| 2024 |
He Y, Shen H, Bi GH, Zhang HY, Soler-Cedeño O, Alton H, Yang Y, Xi ZX. GPR55 is expressed in glutamate neurons and functionally modulates drug taking and seeking in rats and mice. Translational Psychiatry. 14: 101. PMID 38374108 DOI: 10.1038/s41398-024-02820-3 |
0.4 |
|
| 2023 |
Xi ZX, He Y, Shen H, Bi GH, Zhang HY, Soler-Cedeno O, Alton H, Yang Y. GPR55 is expressed in glutamate neurons and functionally modulates nicotine taking and seeking in rats and mice. Research Square. PMID 37886574 DOI: 10.21203/rs.3.rs-3222344/v1 |
0.33 |
|
| 2023 |
Panayi MC, Shetty S, Porod M, Bahena L, Xi ZX, Newman AH, Schoenbaum G. The selective D3-Receptor antagonist VK4-116 effectively treats behavioral inflexibility in rats caused by self-administration and withdrawal from cocaine. Biorxiv : the Preprint Server For Biology. PMID 37732238 DOI: 10.1101/2023.09.03.556083 |
0.45 |
|
| 2023 |
Hempel B, Crissman M, Pari S, Klein B, Bi GH, Alton H, Xi ZX. PPARα and PPARγ are expressed in midbrain dopamine neurons and modulate dopamine- and cannabinoid-mediated behavior in mice. Molecular Psychiatry. PMID 37479780 DOI: 10.1038/s41380-023-02182-0 |
0.356 |
|
| 2023 |
Xi ZX, Hempel B, Crissman M, Pari S, Klein B, Bi GH, Alton H. PPARα and PPARγ are expressed in midbrain dopamine neurons and modulate dopamine- and cannabinoid-mediated behavior in mice. Research Square. PMID 36909477 DOI: 10.21203/rs.3.rs-2614714/v1 |
0.377 |
|
| 2023 |
Gogarnoiu ES, Vogt CD, Sanchez J, Bonifazi A, Saab E, Shaik AB, Soler-Cedeño O, Bi GH, Klein B, Xi ZX, Lane JR, Newman AH. Dopamine D/D Receptor Ligands Based on Cariprazine for the Treatment of Psychostimulant Use Disorders That May Be Dual Diagnosed with Affective Disorders. Journal of Medicinal Chemistry. PMID 36661568 DOI: 10.1021/acs.jmedchem.2c01624 |
0.345 |
|
| 2022 |
Han X, Liang Y, Hempel B, Jordan C, Shen H, Bi GH, Li J, Xi ZX. Cannabinoid CB1 Receptors Are Expressed in a Subset of Dopamine Neurons and Underlie Cannabinoid-Induced Aversion, Hypoactivity, and Anxiolytic Effects in Mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 36517243 DOI: 10.1523/JNEUROSCI.1493-22.2022 |
0.332 |
|
| 2022 |
He Y, Madeo G, Liang Y, Zhang C, Hempel B, Liu X, Mu L, Liu S, Bi GH, Galaj E, Zhang HY, Shen H, McDevitt RA, Gardner EL, Liu QS, ... Xi ZX, et al. A red nucleus-VTA glutamate pathway underlies exercise reward and the therapeutic effect of exercise on cocaine use. Science Advances. 8: eabo1440. PMID 36054363 DOI: 10.1126/sciadv.abo1440 |
0.382 |
|
| 2022 |
Galaj E, Hempel B, Moore A, Klein B, Bi GH, Gardner EL, Seltzman HH, Xi ZX. Therapeutic potential of PIMSR, a novel CB1 receptor neutral antagonist, for cocaine use disorder: evidence from preclinical research. Translational Psychiatry. 12: 286. PMID 35851573 DOI: 10.1038/s41398-022-02059-w |
0.487 |
|
| 2022 |
Newman AH, Xi ZX, Heidbreder C. Current Perspectives on Selective Dopamine D Receptor Antagonists/Partial Agonists as Pharmacotherapeutics for Opioid and Psychostimulant Use Disorders. Current Topics in Behavioral Neurosciences. PMID 35543868 DOI: 10.1007/7854_2022_347 |
0.368 |
|
| 2022 |
Yang HJ, Hempel BJ, Bi GH, He Y, Zhang HY, Gardner EL, Xi ZX. Elevation of extracellular glutamate by blockade of astrocyte glutamate transporters inhibits cocaine reinforcement in rats via a NMDA-GluN2B receptor mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 35091501 DOI: 10.1523/JNEUROSCI.1432-21.2022 |
0.483 |
|
| 2022 |
You ZB, Gardner EL, Galaj E, Moore AR, Buck T, Jordan CJ, Humburg BA, Bi GH, Xi ZX, Leggio L. Involvement of the ghrelin system in the maintenance of oxycodone self-administration: converging evidence from endocrine, pharmacologic and transgenic approaches. Molecular Psychiatry. PMID 35064236 DOI: 10.1038/s41380-022-01438-5 |
0.363 |
|
| 2021 |
You ZB, Galaj E, Alén F, Wang B, Bi GH, Moore AR, Buck T, Crissman M, Pari S, Xi ZX, Leggio L, Wise RA, Gardner EL. Involvement of the ghrelin system in the maintenance and reinstatement of cocaine-motivated behaviors: a role of adrenergic action at peripheral β1 receptors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34923576 DOI: 10.1038/s41386-021-01249-2 |
0.423 |
|
| 2021 |
Gomez JL, Bonaventura J, Keighron J, Wright KM, Marable DL, Rodriguez LA, Lam S, Carlton ML, Ellis RJ, Jordan CJ, Bi GH, Solis O, Pignatelli M, Bannon MJ, Xi ZX, et al. Synaptic Zn potentiates the effects of cocaine on striatal dopamine neurotransmission and behavior. Translational Psychiatry. 11: 570. PMID 34750356 DOI: 10.1038/s41398-021-01693-0 |
0.408 |
|
| 2021 |
He XH, Galaj E, Bi GH, He Y, Hempel B, Wang YL, Gardner EL, Xi ZX. β-caryophyllene, an FDA-Approved Food Additive, Inhibits Methamphetamine-Taking and Methamphetamine-Seeking Behaviors Possibly CB2 and Non-CB2 Receptor Mechanisms. Frontiers in Pharmacology. 12: 722476. PMID 34566647 DOI: 10.3389/fphar.2021.722476 |
0.449 |
|
| 2021 |
Zhang HY, De Biase L, Chandra R, Shen H, Liu QR, Gardner E, Lobo MK, Xi ZX. Repeated cocaine administration upregulates CB receptor expression in striatal medium-spiny neurons that express dopamine D receptors in mice. Acta Pharmacologica Sinica. PMID 34316031 DOI: 10.1038/s41401-021-00712-6 |
0.399 |
|
| 2021 |
Humburg BA, Jordan CJ, Zhang HY, Shen H, Han X, Bi GH, Hempel B, Galaj E, Baumann MH, Xi ZX. Optogenetic brain-stimulation reward: A new procedure to re-evaluate the rewarding versus aversive effects of cannabinoids in dopamine transporter-Cre mice. Addiction Biology. e13005. PMID 33538103 DOI: 10.1111/adb.13005 |
0.401 |
|
| 2021 |
Newman AH, Ku T, Jordan CJ, Bonifazi A, Xi ZX. New Drugs, Old Targets: Tweaking the Dopamine System to Treat Psychostimulant Use Disorders. Annual Review of Pharmacology and Toxicology. 61: 609-628. PMID 33411583 DOI: 10.1146/annurev-pharmtox-030220-124205 |
0.405 |
|
| 2020 |
Galaj E, Xi ZX. Possible Receptor Mechanisms Underlying Cannabidiol Effects on Addictive-like Behaviors in Experimental Animals. International Journal of Molecular Sciences. 22. PMID 33374481 DOI: 10.3390/ijms22010134 |
0.345 |
|
| 2020 |
Li X, Hempel BJ, Yang HJ, Han X, Bi GH, Gardner EL, Xi ZX. Dissecting the role of CB and CB receptors in cannabinoid reward versus aversion using transgenic CB- and CB-knockout mice. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 33334652 DOI: 10.1016/j.euroneuro.2020.11.019 |
0.302 |
|
| 2020 |
Galaj E, Bi GH, Moore A, Chen K, He Y, Gardner E, Xi ZX. Beta-caryophyllene inhibits cocaine self-administration by activation of PPARα and PPARγ: repurposing a FDA-approved food additive for cocaine use disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 33069159 DOI: 10.1038/s41386-020-00885-4 |
0.467 |
|
| 2020 |
Galaj E, Han X, Shen H, Jordan CJ, He Y, Humburg B, Bi GH, Xi ZX. Dissecting the role of GABA neurons in the VTA SNr in opioid reward. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33046548 DOI: 10.1523/JNEUROSCI.0988-20.2020 |
0.311 |
|
| 2020 |
Tanda G, Hersey M, Hempel B, Xi ZX, Newman AH. Modafinil and its structural analogs as atypical dopamine uptake inhibitors and potential medications for psychostimulant use disorder. Current Opinion in Pharmacology. 56: 13-21. PMID 32927246 DOI: 10.1016/J.Coph.2020.07.007 |
0.399 |
|
| 2020 |
Jordan CJ, He Y, Bi GH, You ZB, Cao J, Xi ZX, Newman AH. (±)VK4-40, a Novel D R Partial Agonist, Attenuates Cocaine Reward and Relapse in Rodents. British Journal of Pharmacology. PMID 32851643 DOI: 10.1111/Bph.15244 |
0.522 |
|
| 2020 |
Jordan CJ, Feng ZW, Galaj E, Bi GH, Xue Y, Liang Y, McGuire T, Xie XQ, Xi ZX. Xie2-64, a novel CBR ligand, reduces cocaine abuse-related behaviors in rodents. Neuropharmacology. 108241. PMID 32712273 DOI: 10.1016/J.Neuropharm.2020.108241 |
0.559 |
|
| 2020 |
Schweppe CA, Burzynski C, Jayanthi S, Ladenheim B, Cadet JL, Gardner EL, Xi ZX, van Praag H, Newman AH, Keck TM. Neurochemical and behavioral comparisons of contingent and non-contingent methamphetamine exposure following binge or yoked long-access self-administration paradigms. Psychopharmacology. PMID 32388619 DOI: 10.1007/S00213-020-05513-Z |
0.328 |
|
| 2020 |
Galaj E, Newman AH, Xi ZX. Dopamine D3 receptor-based medication development for the treatment of opioid use disorder: Rationale, progress, and challenges. Neuroscience and Biobehavioral Reviews. PMID 32376243 DOI: 10.1016/J.Neubiorev.2020.04.024 |
0.391 |
|
| 2020 |
Mereu M, Hiranita T, Jordan CJ, Chun LE, Lopez JP, Coggiano MA, Quarterman JC, Bi GH, Keighron JD, Xi ZX, Newman AH, Katz JL, Tanda G. Modafinil potentiates cocaine self-administration by a dopamine-independent mechanism: possible involvement of gap junctions. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32340023 DOI: 10.1038/S41386-020-0680-5 |
0.53 |
|
| 2020 |
Tanda G, Mereu M, Hiranita T, Jordan CJ, Chun LE, Lopez JP, Coggiano MA, Quarterman JC, Bi G, Keighron JD, Xi Z, Katz JL, Newman AH. Gap Junctions Modulate The Effects Of Modafinil On Cocaine Self‐Administration Behavior In A Dopamine‐Independent Fashion In Rats The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04150 |
0.464 |
|
| 2020 |
Galaj E, Bi G, Gardner E, Xi Z. Beta‐caryophyllene, a Volatile Phytocannabinoid, Attenuates Cocaine Self‐administration and Relapse in Rats The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.00005 |
0.461 |
|
| 2019 |
He Y, Galaj E, Bi GH, Wang XF, Gardner E, Xi ZX. Beta-caryophyllene, a dietary terpenoid, inhibits nicotine-taking and nicotine-seeking in rodents. British Journal of Pharmacology. PMID 31883107 DOI: 10.1111/Bph.14969 |
0.316 |
|
| 2019 |
Wang XF, Galaj E, Bi GH, Zhang C, He Y, Zhan J, Bauman M, Gardner EL, Xi ZX. Different receptor mechanisms underlying phytocannabinoid- versus synthetic cannabinoid-induced tetrad effects: Opposite roles of CB1/CB2 versus GPR55 receptors. British Journal of Pharmacology. PMID 31877572 DOI: 10.1111/Bph.14958 |
0.368 |
|
| 2019 |
Jordan CJ, Humburg BA, Thorndike EB, Basha Shaik A, Xi ZX, Baumann MH, Hauck Newman A, Schindler CW. Newly-developed dopamine D3 receptor antagonists, R-VK4-40 and R-VK4-116, do not potentiate cardiovascular effects of cocaine or oxycodone in rats. The Journal of Pharmacology and Experimental Therapeutics. PMID 31562201 DOI: 10.1124/Jpet.119.259390 |
0.482 |
|
| 2019 |
Shaik AB, Kumar V, Bonifazi A, Guerrero A, Cemaj S, Gadiano A, Lam J, Xi ZX, Rais R, Slusher BS, Newman AH. Investigation of novel primary and secondary pharmacophores, and 3-substitution in the linking chain of a series of highly selective and bitopic dopamine D3 receptor antagonists and partial agonists. Journal of Medicinal Chemistry. PMID 31526003 DOI: 10.1021/Acs.Jmedchem.9B00607 |
0.356 |
|
| 2019 |
Xi ZX, Muldoon P, Wang XF, Bi GH, Damaj MI, Lichtman AH, Pertwee RG, Gardner EL. Δ -Tetrahydrocannabivarin has potent anti-nicotine effects in multiple rodent models of nicotine dependence. British Journal of Pharmacology. PMID 31454413 DOI: 10.1111/Bph.14844 |
0.427 |
|
| 2019 |
Galaj E, Bi GH, Yang HJ, Xi ZX. Cannabidiol attenuates the rewarding effects of cocaine in rats by CB2, 5-TH and TRPV1 receptor mechanisms. Neuropharmacology. 107740. PMID 31437433 DOI: 10.1016/j.neuropharm.2019.107740 |
0.493 |
|
| 2019 |
Bi GH, Galaj E, He Y, Xi ZX. Cannabidiol inhibits sucrose self-administration by CB1 and CB2 receptor mechanisms in rodents. Addiction Biology. e12783. PMID 31215752 DOI: 10.1111/adb.12783 |
0.317 |
|
| 2019 |
Jordan CJ, Cao J, Newman AH, Xi ZX. Progress in agonist therapy for substance use disorders: Lessons learned from methadone and buprenorphine. Neuropharmacology. PMID 31009632 DOI: 10.1016/J.Neuropharm.2019.04.015 |
0.41 |
|
| 2019 |
Jordan CJ, Humburg B, Rice M, Bi GH, You ZB, Shaik AB, Cao J, Bonifazi A, Gadiano A, Rais R, Slusher B, Newman AH, Xi ZX. The highly selective dopamine DR antagonist, RVK4-40, attenuates oxycodone reward and augments analgesia in rodents. Neuropharmacology. PMID 30974107 DOI: 10.1016/J.Neuropharm.2019.04.003 |
0.467 |
|
| 2019 |
Ma Z, Gao F, Larsen B, Gao M, Luo Z, Chen D, Ma X, Qiu S, Zhou Y, Xie J, Xi ZX, Wu J. Mechanisms of cannabinoid CB receptor-mediated reduction of dopamine neuronal excitability in mouse ventral tegmental area. Ebiomedicine. PMID 30952618 DOI: 10.1016/J.Ebiom.2019.03.040 |
0.399 |
|
| 2019 |
Newman AH, Cao J, Keighron JD, Jordan CJ, Bi GH, Liang Y, Abramyan AM, Avelar AJ, Tschumi CW, Beckstead MJ, Shi L, Tanda G, Xi ZX. Translating the atypical dopamine uptake inhibitor hypothesis toward therapeutics for treatment of psychostimulant use disorders. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30858517 DOI: 10.1038/S41386-019-0366-Z |
0.524 |
|
| 2019 |
Spiller KJ, Bi GH, He Y, Galaj E, Gardner EL, Xi ZX. Cannabinoid CB and CB receptor mechanisms underlie cannabis reward and aversion in rats. British Journal of Pharmacology. PMID 30767215 DOI: 10.1111/Bph.14625 |
0.399 |
|
| 2019 |
Jordan CJ, Xi ZX. Progress in brain cannabinoid CB receptor research: From genes to behavior. Neuroscience and Biobehavioral Reviews. 98: 208-220. PMID 30611802 DOI: 10.1016/J.Neubiorev.2018.12.026 |
0.319 |
|
| 2018 |
You ZB, Bi GH, Galaj E, Kumar V, Cao J, Gadiano A, Rais R, Slusher BS, Gardner EL, Xi ZX, Newman AH. Dopamine DR antagonist VK4-116 attenuates oxycodone self-administration and reinstatement without compromising its antinociceptive effects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30555159 DOI: 10.1038/S41386-018-0284-5 |
0.37 |
|
| 2018 |
Uhl GR, Martinez MJ, Paik P, Sulima A, Bi GH, Iyer MR, Gardner E, Rice KC, Xi ZX. Cocaine reward is reduced by decreased expression of receptor-type protein tyrosine phosphatase D (PTPRD) and by a novel PTPRD antagonist. Proceedings of the National Academy of Sciences of the United States of America. PMID 30348770 DOI: 10.1073/Pnas.1720446115 |
0.424 |
|
| 2018 |
Gao JT, Jordan C, Bi GH, He Y, Yang HJ, Gardner EL, Xi ZX. Deletion of the type 2 metabotropic glutamate receptor increases heroin abuse vulnerability in transgenic rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30283001 DOI: 10.1038/S41386-018-0231-5 |
0.365 |
|
| 2018 |
Zhan J, Jordan CJ, Bi GH, He XH, Gardner EL, Wang YL, Xi ZX. Genetic deletion of the dopamine D3 receptor increases vulnerability to heroin in mice. Neuropharmacology. PMID 30138692 DOI: 10.1016/J.Neuropharm.2018.08.016 |
0.463 |
|
| 2018 |
He XH, Jordan CJ, Vemuri K, Bi GH, Zhan J, Gardner EL, Makriyannis A, Wang YL, Xi ZX. Cannabinoid CB receptor neutral antagonist AM4113 inhibits heroin self-administration without depressive side effects in rats. Acta Pharmacologica Sinica. PMID 29967454 DOI: 10.1038/S41401-018-0059-X |
0.502 |
|
| 2018 |
Li X, Peng XQ, Jordan CJ, Li J, Bi GH, He Y, Yang HJ, Zhang HY, Gardner EL, Xi ZX. mGluR5 antagonism inhibits cocaine reinforcement and relapse by elevation of extracellular glutamate in the nucleus accumbens via a CB1 receptor mechanism. Scientific Reports. 8: 3686. PMID 29487381 DOI: 10.1038/S41598-018-22087-1 |
0.484 |
|
| 2017 |
You ZB, Gao JT, Bi GH, He Y, Boateng C, Cao J, Gardner EL, Newman AH, Xi ZX. The novel dopamine D3 receptor antagonists/partial agonists CAB2-015 and BAK4-54 inhibit oxycodone-taking and oxycodone-seeking behavior in rats. Neuropharmacology. PMID 28888944 DOI: 10.1016/J.Neuropharm.2017.09.007 |
0.391 |
|
| 2017 |
Yang HJ, Zhang HY, Bi GH, He Y, Gao JT, Xi ZX. Deletion of Type 2 Metabotropic Glutamate Receptor Decreases Sensitivity to Cocaine Reward in Rats. Cell Reports. 20: 319-332. PMID 28700935 DOI: 10.1016/j.celrep.2017.06.046 |
0.441 |
|
| 2017 |
Zhang HY, Bi GH, Yang HJ, He Y, Xue G, Cao JJ, Tanda G, Gardner EL, Newman AH, Xi ZX. The Novel Modafinil Analog, JJC8-016, as a Potential Cocaine Abuse Pharmacotherapeutic. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28266501 DOI: 10.1038/Npp.2017.41 |
0.445 |
|
| 2016 |
Cao J, Slack RD, Bakare OM, Burzynski C, Rais R, Slusher BS, Kopajtic T, Bonifazi A, Ellenberger MP, Yano H, He Y, Bi GH, Xi ZX, Loland CJ, Newman AH. Novel and High Affinity 2-[(Diphenylmethyl)sulfinyl]acetamide (Modafinil) Analogues as Atypical Dopamine Transporter Inhibitors. Journal of Medicinal Chemistry. 59: 10676-10691. PMID 27933960 DOI: 10.1021/Acs.Jmedchem.6B01373 |
0.353 |
|
| 2016 |
Xi ZX, Song R, Li X, Lu GY, Peng XQ, He Y, Bi GH, Shen P, Yang HJ, Zhang H, Li J, Froimowitz M, Gardner EL. CTDP-32,476: A Promising Agonist Therapy for Treatment of Cocaine Addiction. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27534265 DOI: 10.1038/Npp.2016.155 |
0.459 |
|
| 2016 |
Kumar V, Bonifazi A, Ellenberger MP, Keck TM, Pommier E, Rais R, Slusher BS, Gardner E, You ZB, Xi ZX, Newman AH. Highly Selective Dopamine D3 Receptor (D3R) Antagonists and Partial Agonists Based on Eticlopride and the D3R Crystal Structure: New Leads for Opioid Dependence Treatment. Journal of Medicinal Chemistry. PMID 27508895 DOI: 10.1021/Acs.Jmedchem.6B00860 |
0.451 |
|
| 2016 |
Xue X, Yang JY, He Y, Wang LR, Liu P, Yu LS, Bi GH, Zhu MM, Liu YY, Xiang RW, Yang XT, Fan XY, Wang XM, Qi J, Zhang HJ, ... ... Xi ZX, et al. Aggregated single-walled carbon nanotubes attenuate the behavioural and neurochemical effects of methamphetamine in mice. Nature Nanotechnology. PMID 26974957 DOI: 10.1038/Nnano.2016.23 |
0.457 |
|
| 2016 |
Sushchyk SA, Xi ZX, Wang JB. Combination of levo-tetrahydropalmatine and low dose naltrexone: a promising treatment for the prevention of cocaine relapse. The Journal of Pharmacology and Experimental Therapeutics. PMID 26903543 DOI: 10.1124/Jpet.115.229542 |
0.531 |
|
| 2016 |
Zhang HY, Gao M, Shen H, Bi GH, Yang HJ, Liu QR, Wu J, Gardner EL, Bonci A, Xi ZX. Expression of functional cannabinoid CB2 receptor in VTA dopamine neurons in rats. Addiction Biology. PMID 26833913 DOI: 10.1111/Adb.12367 |
0.416 |
|
| 2016 |
Wang JB, Sushchyk S, Xi Z. PM312. Combination of levo-tetrahydropalmatine and low dose naltrexone: a promising treatment for the prevention of cocaine relapse. The International Journal of Neuropsychopharmacology. 19: 11-11. DOI: 10.1093/Ijnp/Pyw041.312 |
0.427 |
|
| 2016 |
Gardner EL, Bi G, Thakur G, Makriyannis A, Seltzman HH, He X, Xi Z. PM288. Preclinical Evaluation of Neutral Cannabinoid CB1 Receptor Antagonists and Cannabinoid CB1 Receptor Negative Allosteric Modulators for Treating Drug Addiction The International Journal of Neuropsychopharmacology. 19: 3-3. DOI: 10.1093/Ijnp/Pyw041.288 |
0.371 |
|
| 2015 |
Tsai SA, Chuang JY, Tsai MS, Wang XF, Xi ZX, Hung JJ, Chang WC, Bonci A, Su TP. Sigma-1 receptor mediates cocaine-induced transcriptional regulation by recruiting chromatin-remodeling factors at the nuclear envelope. Proceedings of the National Academy of Sciences of the United States of America. PMID 26554014 DOI: 10.1073/pnas.1518894112 |
0.392 |
|
| 2015 |
Wang XF, Bi GH, He Y, Yang HJ, Gao JT, Okunola-Bakare OM, Slack RD, Gardner EL, Xi ZX, Newman AH. R-modafinil attenuates nicotine-taking and nicotine-seeking behavior in alcohol-preferring rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1762-71. PMID 25613829 DOI: 10.1038/Npp.2015.24 |
0.372 |
|
| 2015 |
Zhang HY, Bi GH, Li X, Li J, Qu H, Zhang SJ, Li CY, Onaivi ES, Gardner EL, Xi ZX, Liu QR. Species differences in cannabinoid receptor 2 and receptor responses to cocaine self-administration in mice and rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1037-51. PMID 25374096 DOI: 10.1038/Npp.2014.297 |
0.381 |
|
| 2014 |
Zhang HY, Gao M, Liu QR, Bi GH, Li X, Yang HJ, Gardner EL, Wu J, Xi ZX. Cannabinoid CB2 receptors modulate midbrain dopamine neuronal activity and dopamine-related behavior in mice. Proceedings of the National Academy of Sciences of the United States of America. 111: E5007-15. PMID 25368177 DOI: 10.1073/Pnas.1413210111 |
0.334 |
|
| 2014 |
Song R, Bi GH, Zhang HY, Yang RF, Gardner EL, Li J, Xi ZX. Blockade of D3 receptors by YQA14 inhibits cocaine's rewarding effects and relapse to drug-seeking behavior in rats. Neuropharmacology. 77: 398-405. PMID 24176392 DOI: 10.1016/J.Neuropharm.2013.10.010 |
0.473 |
|
| 2014 |
Keck TM, Zou MF, Bi GH, Zhang HY, Wang XF, Yang HJ, Srivastava R, Gardner EL, Xi ZX, Newman AH. A novel mGluR5 antagonist, MFZ 10-7, inhibits cocaine-taking and cocaine-seeking behavior in rats. Addiction Biology. 19: 195-209. PMID 24001208 DOI: 10.1111/Adb.12086 |
0.456 |
|
| 2014 |
Gardner EL, Zhang H, Peng X, Su R, Yang R, Li J, Xi Z, Song R. Dopamine D3 receptors underlie cocaine-induced conditioned place preference in mice Drug and Alcohol Dependence. 140: e67. DOI: 10.1016/J.Drugalcdep.2014.02.201 |
0.405 |
|
| 2013 |
Song R, Zhang HY, Peng XQ, Su RB, Yang RF, Li J, Xi ZX, Gardner EL. Dopamine D(3) receptor deletion or blockade attenuates cocaine-induced conditioned place preference in mice. Neuropharmacology. 72: 82-7. PMID 23643749 DOI: 10.1016/J.Neuropharm.2013.04.042 |
0.442 |
|
| 2013 |
Keck TM, Yang HJ, Bi GH, Huang Y, Zhang HY, Srivastava R, Gardner EL, Newman AH, Xi ZX. Fenobam sulfate inhibits cocaine-taking and cocaine-seeking behavior in rats: implications for addiction treatment in humans. Psychopharmacology. 229: 253-65. PMID 23615919 DOI: 10.1007/S00213-013-3106-9 |
0.439 |
|
| 2013 |
Li X, Higley A, Song R, Xi ZX. Effects of metabotropic glutamate receptor ligands on male sexual behavior in rats. Neuropharmacology. 66: 373-81. PMID 22968089 DOI: 10.1016/J.Neuropharm.2012.08.006 |
0.362 |
|
| 2013 |
Xi ZX, Li X, Li J, Peng XQ, Song R, Gaál J, Gardner EL. Blockade of dopamine D3 receptors in the nucleus accumbens and central amygdala inhibits incubation of cocaine craving in rats. Addiction Biology. 18: 665-77. PMID 22913325 DOI: 10.1111/J.1369-1600.2012.00486.X |
0.558 |
|
| 2013 |
Li X, Xi ZX, Markou A. Metabotropic glutamate 7 (mGlu7) receptor: a target for medication development for the treatment of cocaine dependence. Neuropharmacology. 66: 12-23. PMID 22546614 DOI: 10.1016/J.Neuropharm.2012.04.010 |
0.57 |
|
| 2013 |
Yang H, Bi G, Zhang H, Peng X, Gardner EL, Xi Z. The Anticonvulsant Tiagabine Inhibits Cocaine' s Rewarding Effects, but has No Effect on Reinstatement of Cocaine-Seeking Behavior in Rats Biochemical Pharmacology. 2013: 1-6. DOI: 10.4172/2167-0501.S1-005 |
0.533 |
|
| 2012 |
Song R, Zhang HY, Li X, Bi GH, Gardner EL, Xi ZX. Increased vulnerability to cocaine in mice lacking dopamine D3 receptors. Proceedings of the National Academy of Sciences of the United States of America. 109: 17675-80. PMID 23045656 DOI: 10.1073/Pnas.1205297109 |
0.423 |
|
| 2012 |
Srivastava R, Xi ZX, Gardner EL. Cocaine-taking and cocaine-seeking behaviors in rats remain stable after systemic administration of GYKI 52466: a non-competitive AMPA receptor antagonist. Neuroscience Letters. 508: 106-9. PMID 22206835 DOI: 10.1016/J.Neulet.2011.12.028 |
0.541 |
|
| 2012 |
Song R, Yang RF, Wu N, Su RB, Li J, Peng XQ, Li X, Gaál J, Xi ZX, Gardner EL. YQA14: a novel dopamine D3 receptor antagonist that inhibits cocaine self-administration in rats and mice, but not in D3 receptor-knockout mice. Addiction Biology. 17: 259-73. PMID 21507153 DOI: 10.1111/J.1369-1600.2011.00317.X |
0.501 |
|
| 2011 |
Xi ZX, Peng XQ, Li X, Song R, Zhang HY, Liu QR, Yang HJ, Bi GH, Li J, Gardner EL. Brain cannabinoid CB₂ receptors modulate cocaine's actions in mice. Nature Neuroscience. 14: 1160-6. PMID 21785434 DOI: 10.1038/Nn.2874 |
0.476 |
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| 2011 |
Higley AE, Kiefer SW, Li X, Gaál J, Xi ZX, Gardner EL. Dopamine D(3) receptor antagonist SB-277011A inhibits methamphetamine self-administration and methamphetamine-induced reinstatement of drug-seeking in rats. European Journal of Pharmacology. 659: 187-92. PMID 21466803 DOI: 10.1016/J.Ejphar.2011.02.046 |
0.51 |
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| 2011 |
Higley AE, Spiller K, Grundt P, Newman AH, Kiefer SW, Xi ZX, Gardner EL. PG01037, a novel dopamine D3 receptor antagonist, inhibits the effects of methamphetamine in rats. Journal of Psychopharmacology (Oxford, England). 25: 263-73. PMID 20142301 DOI: 10.1177/0269881109358201 |
0.451 |
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| 2010 |
Peng XQ, Xi ZX, Li X, Spiller K, Li J, Chun L, Wu KM, Froimowitz M, Gardner EL. Is slow-onset long-acting monoamine transport blockade to cocaine as methadone is to heroin? Implication for anti-addiction medications. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 2564-78. PMID 20827272 DOI: 10.1038/Npp.2010.133 |
0.55 |
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| 2010 |
Li X, Li J, Gardner EL, Xi ZX. Activation of mGluR7s inhibits cocaine-induced reinstatement of drug-seeking behavior by a nucleus accumbens glutamate-mGluR2/3 mechanism in rats. Journal of Neurochemistry. 114: 1368-80. PMID 20534005 DOI: 10.1111/J.1471-4159.2010.06851.X |
0.567 |
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| 2010 |
Peng XQ, Gardner EL, Xi ZX. Gamma-vinyl GABA increases nonvesicular release of GABA and glutamate in the nucleus accumbens in rats via action on anion channels and GABA transporters. Psychopharmacology. 208: 511-9. PMID 20033132 DOI: 10.1007/S00213-009-1753-7 |
0.331 |
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| 2010 |
Xi ZX, Li X, Peng XQ, Li J, Chun L, Gardner EL, Thomas AG, Slusher BS, Ashby CR. Inhibition of NAALADase by 2-PMPA attenuates cocaine-induced relapse in rats: a NAAG-mGluR2/3-mediated mechanism. Journal of Neurochemistry. 112: 564-76. PMID 19895667 DOI: 10.1111/J.1471-4159.2009.06478.X |
0.481 |
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| 2010 |
Peng XQ, Li J, Gardner EL, Ashby CR, Thomas A, Wozniak K, Slusher BS, Xi ZX. Oral administration of the NAALADase inhibitor GPI-5693 attenuates cocaine-induced reinstatement of drug-seeking behavior in rats. European Journal of Pharmacology. 627: 156-61. PMID 19887067 DOI: 10.1016/J.Ejphar.2009.10.062 |
0.455 |
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| 2010 |
Xi ZX, Kiyatkin M, Li X, Peng XQ, Wiggins A, Spiller K, Li J, Gardner EL. N-acetylaspartylglutamate (NAAG) inhibits intravenous cocaine self-administration and cocaine-enhanced brain-stimulation reward in rats. Neuropharmacology. 58: 304-13. PMID 19559037 DOI: 10.1016/J.Neuropharm.2009.06.016 |
0.577 |
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| 2009 |
Yang S, Salmeron BJ, Ross TJ, Xi ZX, Stein EA, Yang Y. Lower glutamate levels in rostral anterior cingulate of chronic cocaine users - A (1)H-MRS study using TE-averaged PRESS at 3 T with an optimized quantification strategy. Psychiatry Research. 174: 171-6. PMID 19906515 DOI: 10.1016/j.pscychresns.2009.05.004 |
0.551 |
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| 2009 |
Xi ZX, Spiller K, Gardner EL. Mechanism-based medication development for the treatment of nicotine dependence. Acta Pharmacologica Sinica. 30: 723-39. PMID 19434058 DOI: 10.1038/Aps.2009.46 |
0.372 |
|
| 2009 |
Xi ZX, Kleitz HK, Deng X, Ladenheim B, Peng XQ, Li X, Gardner EL, Stein EA, Cadet JL. A single high dose of methamphetamine increases cocaine self-administration by depletion of striatal dopamine in rats. Neuroscience. 161: 392-402. PMID 19336247 DOI: 10.1016/J.Neuroscience.2009.03.060 |
0.603 |
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| 2009 |
Li X, Li J, Peng XQ, Spiller K, Gardner EL, Xi ZX. Metabotropic glutamate receptor 7 modulates the rewarding effects of cocaine in rats: involvement of a ventral pallidal GABAergic mechanism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1783-96. PMID 19158667 DOI: 10.1038/Npp.2008.236 |
0.58 |
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| 2009 |
Peng XQ, Ashby CR, Spiller K, Li X, Li J, Thomasson N, Millan MJ, Mocaër E, Muńoz C, Gardner EL, Xi ZX. The preferential dopamine D3 receptor antagonist S33138 inhibits cocaine reward and cocaine-triggered relapse to drug-seeking behavior in rats. Neuropharmacology. 56: 752-60. PMID 19136017 DOI: 10.1016/J.Neuropharm.2008.12.007 |
0.549 |
|
| 2009 |
Li X, Hoffman AF, Peng XQ, Lupica CR, Gardner EL, Xi ZX. Attenuation of basal and cocaine-enhanced locomotion and nucleus accumbens dopamine in cannabinoid CB1-receptor-knockout mice. Psychopharmacology. 204: 1-11. PMID 19099297 DOI: 10.1007/S00213-008-1432-0 |
0.53 |
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| 2008 |
Xi ZX, Gardner EL. Hypothesis-driven medication discovery for the treatment of psychostimulant addiction. Current Drug Abuse Reviews. 1: 303-27. PMID 19430578 DOI: 10.2174/1874473710801030303 |
0.417 |
|
| 2008 |
Li X, Gardner EL, Xi ZX. The metabotropic glutamate receptor 7 (mGluR7) allosteric agonist AMN082 modulates nucleus accumbens GABA and glutamate, but not dopamine, in rats. Neuropharmacology. 54: 542-51. PMID 18155073 DOI: 10.1016/J.Neuropharm.2007.11.005 |
0.417 |
|
| 2008 |
Peng XQ, Li X, Li J, Ramachandran PV, Gagare PD, Pratihar D, Ashby CR, Gardner EL, Xi ZX. Effects of gabapentin on cocaine self-administration, cocaine-triggered relapse and cocaine-enhanced nucleus accumbens dopamine in rats. Drug and Alcohol Dependence. 97: 207-15. PMID 18065162 DOI: 10.1016/J.Drugalcdep.2007.09.019 |
0.542 |
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| 2008 |
Peng XQ, Li X, Gilbert JG, Pak AC, Ashby CR, Brodie JD, Dewey SL, Gardner EL, Xi ZX. Gamma-vinyl GABA inhibits cocaine-triggered reinstatement of drug-seeking behavior in rats by a non-dopaminergic mechanism. Drug and Alcohol Dependence. 97: 216-25. PMID 18063319 DOI: 10.1016/J.Drugalcdep.2007.10.004 |
0.55 |
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| 2008 |
Spiller K, Xi ZX, Peng XQ, Newman AH, Ashby CR, Heidbreder C, Gaál J, Gardner EL. The selective dopamine D3 receptor antagonists SB-277011A and NGB 2904 and the putative partial D3 receptor agonist BP-897 attenuate methamphetamine-enhanced brain stimulation reward in rats. Psychopharmacology. 196: 533-42. PMID 17985117 DOI: 10.1007/S00213-007-0986-6 |
0.468 |
|
| 2008 |
Xi ZX, Spiller K, Pak AC, Gilbert J, Dillon C, Li X, Peng XQ, Gardner EL. Cannabinoid CB1 receptor antagonists attenuate cocaine's rewarding effects: experiments with self-administration and brain-stimulation reward in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 1735-45. PMID 17728698 DOI: 10.1038/Sj.Npp.1301552 |
0.547 |
|
| 2007 |
Xi ZX, Yang Z, Li SJ, Li X, Dillon C, Peng XQ, Spiller K, Gardner EL. Levo-tetrahydropalmatine inhibits cocaine's rewarding effects: experiments with self-administration and brain-stimulation reward in rats. Neuropharmacology. 53: 771-82. PMID 17888459 DOI: 10.1016/J.Neuropharm.2007.08.004 |
0.529 |
|
| 2007 |
Xi ZX, Gardner EL. Pharmacological actions of NGB 2904, a selective dopamine D3 receptor antagonist, in animal models of drug addiction. Cns Drug Reviews. 13: 240-59. PMID 17627675 DOI: 10.1111/J.1527-3458.2007.00013.X |
0.555 |
|
| 2007 |
Lu H, Xi ZX, Gitajn L, Rea W, Yang Y, Stein EA. Cocaine-induced brain activation detected by dynamic manganese-enhanced magnetic resonance imaging (MEMRI). Proceedings of the National Academy of Sciences of the United States of America. 104: 2489-94. PMID 17287361 DOI: 10.1073/Pnas.0606983104 |
0.554 |
|
| 2006 |
Pak AC, Ashby CR, Heidbreder CA, Pilla M, Gilbert J, Xi ZX, Gardner EL. The selective dopamine D3 receptor antagonist SB-277011A reduces nicotine-enhanced brain reward and nicotine-paired environmental cue functions. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 9: 585-602. PMID 16942635 DOI: 10.1017/S1461145706006560 |
0.445 |
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| 2006 |
Xi ZX, Gilbert JG, Peng XQ, Pak AC, Li X, Gardner EL. Cannabinoid CB1 receptor antagonist AM251 inhibits cocaine-primed relapse in rats: role of glutamate in the nucleus accumbens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 8531-6. PMID 16914679 DOI: 10.1523/Jneurosci.0726-06.2006 |
0.564 |
|
| 2006 |
Xi ZX, Newman AH, Gilbert JG, Pak AC, Peng XQ, Ashby CR, Gitajn L, Gardner EL. The novel dopamine D3 receptor antagonist NGB 2904 inhibits cocaine's rewarding effects and cocaine-induced reinstatement of drug-seeking behavior in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1393-405. PMID 16205781 DOI: 10.1038/Sj.Npp.1300912 |
0.552 |
|
| 2005 |
Xi ZX, Gilbert JG, Pak AC, Ashby CR, Heidbreder CA, Gardner EL. Selective dopamine D3 receptor antagonism by SB-277011A attenuates cocaine reinforcement as assessed by progressive-ratio and variable-cost-variable-payoff fixed-ratio cocaine self-administration in rats. The European Journal of Neuroscience. 21: 3427-38. PMID 16026480 DOI: 10.1111/J.1460-9568.2005.04159.X |
0.514 |
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| 2005 |
Heidbreder CA, Gardner EL, Xi ZX, Thanos PK, Mugnaini M, Hagan JJ, Ashby CR. The role of central dopamine D3 receptors in drug addiction: a review of pharmacological evidence. Brain Research. Brain Research Reviews. 49: 77-105. PMID 15960988 DOI: 10.1016/J.Brainresrev.2004.12.033 |
0.4 |
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| 2005 |
Gilbert JG, Newman AH, Gardner EL, Ashby CR, Heidbreder CA, Pak AC, Peng XQ, Xi ZX. Acute administration of SB-277011A, NGB 2904, or BP 897 inhibits cocaine cue-induced reinstatement of drug-seeking behavior in rats: role of dopamine D3 receptors. Synapse (New York, N.Y.). 57: 17-28. PMID 15858839 DOI: 10.1002/Syn.20152 |
0.535 |
|
| 2004 |
Xi ZX, Wu G, Stein EA, Li SJ. Opiate tolerance by heroin self-administration: an fMRI study in rat. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 52: 108-14. PMID 15236373 DOI: 10.1002/Mrm.20119 |
0.567 |
|
| 2004 |
Gorelick DA, Gardner EL, Xi ZX. Agents in development for the management of cocaine abuse. Drugs. 64: 1547-73. PMID 15233592 DOI: 10.2165/00003495-200464140-00004 |
0.533 |
|
| 2004 |
Luo F, Xi ZX, Wu G, Liu C, Gardner EL, Li SJ. Attenuation of brain response to heroin correlates with the reinstatement of heroin-seeking in rats by fMRI. Neuroimage. 22: 1328-35. PMID 15219605 DOI: 10.1016/J.Neuroimage.2004.03.017 |
0.406 |
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| 2004 |
Xi ZX, Gilbert J, Campos AC, Kline N, Ashby CR, Hagan JJ, Heidbreder CA, Gardner EL. Blockade of mesolimbic dopamine D3 receptors inhibits stress-induced reinstatement of cocaine-seeking in rats. Psychopharmacology. 176: 57-65. PMID 15083257 DOI: 10.1007/S00213-004-1858-Y |
0.534 |
|
| 2003 |
Kalivas PW, McFarland K, Bowers S, Szumlinski K, Xi ZX, Baker D. Glutamate transmission and addiction to cocaine. Annals of the New York Academy of Sciences. 1003: 169-75. PMID 14684444 DOI: 10.1196/Annals.1300.009 |
0.515 |
|
| 2003 |
Xi ZX, Shen H, Baker DA, Kalivas PW. Inhibition of non-vesicular glutamate release by group III metabotropic glutamate receptors in the nucleus accumbens. Journal of Neurochemistry. 87: 1204-12. PMID 14622100 DOI: 10.1046/J.1471-4159.2003.02093.X |
0.314 |
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| 2003 |
Xi ZX, Ramamoorthy S, Shen H, Lake R, Samuvel DJ, Kalivas PW. GABA transmission in the nucleus accumbens is altered after withdrawal from repeated cocaine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 3498-505. PMID 12716959 DOI: 10.1523/Jneurosci.23-08-03498.2003 |
0.474 |
|
| 2003 |
Xi ZX, Stein EA. Opiate self-administration. Methods in Molecular Medicine. 84: 251-64. PMID 12703330 DOI: 10.1385/1-59259-379-8:251 |
0.487 |
|
| 2002 |
Xi ZX, Wu G, Stein EA, Li SJ. GABAergic mechanisms of heroin-induced brain activation assessed with functional MRI. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 48: 838-43. PMID 12417998 DOI: 10.1002/Mrm.10282 |
0.565 |
|
| 2002 |
Xi ZX, Stein EA. Blockade of ionotropic glutamatergic transmission in the ventral tegmental area reduces heroin reinforcement in rat. Psychopharmacology. 164: 144-50. PMID 12404076 DOI: 10.1007/S00213-002-1190-3 |
0.607 |
|
| 2002 |
Xi ZX, Ramamoorthy S, Baker DA, Shen H, Samuvel DJ, Kalivas PW. Modulation of group II metabotropic glutamate receptor signaling by chronic cocaine. The Journal of Pharmacology and Experimental Therapeutics. 303: 608-15. PMID 12388642 DOI: 10.1124/Jpet.102.039735 |
0.509 |
|
| 2002 |
Baker DA, Xi ZX, Shen H, Swanson CJ, Kalivas PW. The origin and neuronal function of in vivo nonsynaptic glutamate. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9134-41. PMID 12388621 DOI: 10.1523/Jneurosci.22-20-09134.2002 |
0.332 |
|
| 2002 |
Xi ZX, Stein EA. GABAergic mechanisms of opiate reinforcement . Alcohol and Alcoholism (Oxford, Oxfordshire). 37: 485-94. PMID 12217944 DOI: 10.1093/Alcalc/37.5.485 |
0.568 |
|
| 2002 |
Xi ZX, Baker DA, Shen H, Carson DS, Kalivas PW. Group II metabotropic glutamate receptors modulate extracellular glutamate in the nucleus accumbens. The Journal of Pharmacology and Experimental Therapeutics. 300: 162-71. PMID 11752112 DOI: 10.1124/Jpet.300.1.162 |
0.311 |
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| 2000 |
Xi ZX, Stein EA. Increased mesolimbic GABA concentration blocks heroin self-administration in the rat. The Journal of Pharmacology and Experimental Therapeutics. 294: 613-9. PMID 10900239 |
0.503 |
|
| 2000 |
Xu H, Li SJ, Bodurka J, Zhao X, Xi ZX, Stein EA. Heroin-induced neuronal activation in rat brain assessed by functional MRI. Neuroreport. 11: 1085-92. PMID 10790887 DOI: 10.1097/00001756-200004070-00036 |
0.498 |
|
| 1999 |
Xi ZX, Stein EA. Baclofen inhibits heroin self-administration behavior and mesolimbic dopamine release. The Journal of Pharmacology and Experimental Therapeutics. 290: 1369-74. PMID 10454516 |
0.575 |
|
| 1998 |
Xi ZX, Stein EA. Nucleus accumbens dopamine release modulation by mesolimbic GABAA receptors-an in vivo electrochemical study. Brain Research. 798: 156-65. PMID 9666112 DOI: 10.1016/S0006-8993(98)00406-5 |
0.614 |
|
| 1998 |
Xi ZX, Fuller SA, Stein EA. Dopamine release in the nucleus accumbens during heroin self-administration is modulated by kappa opioid receptors: an in vivo fast-cyclic voltammetry study. The Journal of Pharmacology and Experimental Therapeutics. 284: 151-61. PMID 9435173 |
0.556 |
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