Karmella A. Haynes, Ph.D. - Publications

Affiliations: 
Washington University, Saint Louis, St. Louis, MO 
Area:
the role that chromatin structure plays in gene regulation

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Kim SH, Haynes KA. Reader-Effectors as Actuators of Epigenome Editing. Methods in Molecular Biology (Clifton, N.J.). 2842: 103-127. PMID 39012592 DOI: 10.1007/978-1-0716-4051-7_5  0.333
2022 Haynes KA, Priode JH. Rapid Single-Pot Assembly of Modular Chromatin Proteins for Epigenetic Engineering. Methods in Molecular Biology (Clifton, N.J.). 2599: 191-214. PMID 36427151 DOI: 10.1007/978-1-0716-2847-8_14  0.346
2022 Franklin KA, Shields CE, Haynes KA. Beyond the marks: reader-effectors as drivers of epigenetics and chromatin engineering. Trends in Biochemical Sciences. 47: 417-432. PMID 35427480 DOI: 10.1016/j.tibs.2022.03.002  0.376
2020 Daer R, Hamna F, Barrett CM, Haynes KA. Site-directed targeting of transcriptional activation-associated proteins to repressed chromatin restores CRISPR activity. Apl Bioengineering. 4: 016102. PMID 31967103 DOI: 10.1063/1.5127302  0.319
2020 Barrett CM, McCracken R, Elmer J, Haynes KA. Components from the Human c-myb Transcriptional Regulation System Reactivate Epigenetically Repressed Transgenes. International Journal of Molecular Sciences. 21. PMID 31947658 DOI: 10.3390/Ijms21020530  0.496
2019 Tekel SJ, Smith CL, Lopez B, Mani A, Connot C, Livingstone X, Haynes KA. Engineered Orthogonal Quorum Sensing Systems for Synthetic Gene Regulation in . Frontiers in Bioengineering and Biotechnology. 7: 80. PMID 31058147 DOI: 10.3389/Fbioe.2019.00080  0.337
2018 Olney KC, Nyer DB, Vargas DA, Wilson Sayres MA, Haynes KA. The synthetic histone-binding regulator protein PcTF activates interferon genes in breast cancer cells. Bmc Systems Biology. 12: 83. PMID 30253781 DOI: 10.1186/S12918-018-0608-4  0.4
2018 Christensen MD, Nitiyanandan R, Meraji S, Davis R, Godeshala S, Goklany S, Haynes K, Rege K. An inhibitor screen identifies histone-modifying enzymes as mediators of polymer-mediated transgene expression from plasmid DNA. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 29964136 DOI: 10.1016/J.Jconrel.2018.06.030  0.413
2018 Tekel SJ, Barrett CM, Vargas DA, Haynes KA. Design, construction, and validation of histone-binding effectors in vitro and in cells. Biochemistry. PMID 29791133 DOI: 10.1021/Acs.Biochem.8B00327  0.413
2018 Tekel SJ, Vargas DA, Song L, LaBear J, Caplan MR, Haynes KA. Tandem Histone-Binding Domains Enhance the Activity of a Synthetic Chromatin Effector. Acs Synthetic Biology. PMID 29429329 DOI: 10.1021/Acssynbio.7B00281  0.476
2017 Nyer DB, Daer RM, Vargas D, Hom C, Haynes KA. Regulation of cancer epigenomes with a histone-binding synthetic transcription factor. Npj Genomic Medicine. 2. PMID 28919981 DOI: 10.1038/S41525-016-0002-3  0.436
2017 Tekel SJ, Haynes KA. Molecular structures guide the engineering of chromatin. Nucleic Acids Research. PMID 28609787 DOI: 10.1093/Nar/Gkx531  0.421
2016 Daer R, Cutts JP, Brafman DA, Haynes KA. The impact of chromatin dynamics on Cas9-mediated genome editing in human cells. Acs Synthetic Biology. PMID 27783893 DOI: 10.1021/Acssynbio.5B00299  0.42
2015 Davis RM, Muller RY, Haynes KA. Corrigendum: Can the Natural Diversity of Quorum-Sensing Advance Synthetic Biology? Frontiers in Bioengineering and Biotechnology. 3: 99. PMID 26913281 DOI: 10.3389/Fbioe.2015.00099  0.306
2015 Elmer JJ, Christensen MD, Barua S, Lehrman J, Haynes KA, Rege K. The histone deacetylase inhibitor entinostat enhances polymer-mediated transgene expression in cancer cell lines. Biotechnology and Bioengineering. PMID 26614912 DOI: 10.1002/Bit.25898  0.401
2012 Silver PA, Haynes K, Weiss R. Synthetic meets cell biology Molecular Biology of the Cell. 23: 967. DOI: 10.1091/Mbc.E11-12-0978  0.339
2011 Haynes KA, Silver PA. Synthetic reversal of epigenetic silencing. The Journal of Biological Chemistry. 286: 27176-82. PMID 21669865 DOI: 10.1074/Jbc.C111.229567  0.441
2008 Haynes KA, Broderick ML, Brown AD, Butner TL, Dickson JO, Harden WL, Heard LH, Jessen EL, Malloy KJ, Ogden BJ, Rosemond S, Simpson S, Zwack E, Campbell AM, Eckdahl TT, et al. Engineering bacteria to solve the Burnt Pancake Problem. Journal of Biological Engineering. 2: 8. PMID 18492232 DOI: 10.1186/1754-1611-2-8  0.317
2008 Riddle NC, Leung W, Haynes KA, Granok H, Wuller J, Elgin SC. An investigation of heterochromatin domains on the fourth chromosome of Drosophila melanogaster. Genetics. 178: 1177-91. PMID 18245350 DOI: 10.1534/Genetics.107.081828  0.661
2007 Haynes KA, Gracheva E, Elgin SC. A Distinct type of heterochromatin within Drosophila melanogaster chromosome 4. Genetics. 175: 1539-42. PMID 17194780 DOI: 10.1534/Genetics.106.066407  0.614
2007 Haynes KA, Broderick ML, Brown AD, Butner TL, Harden L, Heard L, Jessen E, Malloy K, Ogden B, Rosemond S, Simpson S, Zwack E, Campbell AM, Eckdahl T, Heyer LJ, et al. Computing with living hardware Iet Synthetic Biology. 1: 44-47. DOI: 10.1049/Iet-Stb:20070004  0.306
2006 Haynes KA, Caudy AA, Collins L, Elgin SC. Element 1360 and RNAi components contribute to HP1-dependent silencing of a pericentric reporter. Current Biology : Cb. 16: 2222-7. PMID 17113386 DOI: 10.1016/J.Cub.2006.09.035  0.614
2004 Haynes KA, Leibovitch BA, Rangwala SH, Craig C, Elgin SC. Analyzing heterochromatin formation using chromosome 4 of Drosophila melanogaster. Cold Spring Harbor Symposia On Quantitative Biology. 69: 267-72. PMID 16117658 DOI: 10.1101/Sqb.2004.69.267  0.644
2004 Sun FL, Haynes K, Simpson CL, Lee SD, Collins L, Wuller J, Eissenberg JC, Elgin SC. cis-Acting determinants of heterochromatin formation on Drosophila melanogaster chromosome four. Molecular and Cellular Biology. 24: 8210-20. PMID 15340080 DOI: 10.1128/Mcb.24.18.8210-8220.2004  0.674
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