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Yiwei Li, Ph.D. - Publications

Affiliations: 
Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
chemistry, biology, and medicine of natural and designed molecules
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19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2009 Hutchinson JH, Li Y, Arruda JM, Baccei C, Bain G, Chapman C, Correa L, Darlington J, King CD, Lee C, Lorrain D, Prodanovich P, Rong H, Santini A, Stock N, et al. 5-lipoxygenase-activating protein inhibitors: development of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid (AM103). Journal of Medicinal Chemistry. 52: 5803-15. PMID 19739647 DOI: 10.1021/Jm900945D  0.329
2006 Nicolaou KC, Koftis TV, Vyskocil S, Petrovic G, Tang W, Frederick MO, Chen DY, Li Y, Ling T, Yamada YM. Total synthesis and structural elucidation of azaspiracid-1. Final assignment and total synthesis of the correct structure of azaspiracid-1. Journal of the American Chemical Society. 128: 2859-72. PMID 16506764 DOI: 10.1021/Ja054750Q  0.747
2006 Nicolaou KC, Chen DY, Li Y, Uesaka N, Petrovic G, Koftis TV, Bernal F, Frederick MO, Govindasamy M, Ling T, Pihko PM, Tang W, Vyskocil S. Total synthesis and structural elucidation of azaspiracid-1. Synthesis-based analysis of originally proposed structures and indication of their non-identity to the natural product. Journal of the American Chemical Society. 128: 2258-67. PMID 16478179 DOI: 10.1021/Ja054748Z  0.755
2006 Nicolaou K, Koftis T, Vyskocil S, Petrovic G, Tang W, Frederick M, Chen D, Ling T, Li Y, Yamada Y. Synthesis and Structural Elucidation of Azaspiracid-1 Synfacts. 2006: 0748-0748. DOI: 10.1055/S-2006-941937  0.722
2004 Nicolaou KC, Vyskocil S, Koftis TV, Yamada YM, Ling T, Chen DY, Tang W, Petrovic G, Frederick MO, Li Y, Satake M. Structural revision and total synthesis of azaspiracid-1, part 1: intelligence gathering and tentative proposal. Angewandte Chemie (International Ed. in English). 43: 4312-8. PMID 15368380 DOI: 10.1002/Anie.200460695  0.723
2004 Nicolaou KC, Vyskocil S, Koftis TV, Yamada YMA, Ling T, Chen DY, Tang W, Petrovic G, Frederick MO, Li Y, Satake M. Cover Picture: Structural Revision and Total Synthesis of Azaspiracid-1, Part 1: Intelligence Gathering and Tentative Proposal (Angew. Chem. Int. Ed. 33/2004) Angewandte Chemie International Edition. 43: 4239-4239. DOI: 10.1002/Anie.200490111  0.67
2004 Nicolaou KC, Vyskocil S, Koftis TV, Yamada YMA, Ling T, Chen DY, Tang W, Petrovic G, Frederick MO, Li Y, Satake M. Titelbild: Structural Revision and Total Synthesis of Azaspiracid-1, Part 1: Intelligence Gathering and Tentative Proposal (Angew. Chem. 33/2004) Angewandte Chemie. 116: 4335-4335. DOI: 10.1002/Ange.200490110  0.675
2003 Nicolaou KC, Li Y, Sugita K, Monenschein H, Guntupalli P, Mitchell HJ, Fylaktakidou KC, Vourloumis D, Giannakakou P, O'Brate A. Total synthesis of apoptolidin: completion of the synthesis and analogue synthesis and evaluation. Journal of the American Chemical Society. 125: 15443-54. PMID 14664590 DOI: 10.1021/Ja030496V  0.679
2003 Nicolaou KC, Fylaktakidou KC, Monenschein H, Li Y, Weyershausen B, Mitchell HJ, Wei HX, Guntupalli P, Hepworth D, Sugita K. Total synthesis of apoptolidin: construction of enantiomerically pure fragments. Journal of the American Chemical Society. 125: 15433-42. PMID 14664589 DOI: 10.1021/Ja0304953  0.696
2003 Nicolaou KC, Chen DY, Li Y, Qian W, Ling T, Vyskocil S, Koftis TV, Govindasamy M, Uesaka N. Total synthesis of the proposed azaspiracid-1 structure, part 2: coupling of the C1-C20, C21-C27, and C28-C40 fragments and completion of the synthesis. Angewandte Chemie (International Ed. in English). 42: 3649-53. PMID 12916037 DOI: 10.1002/Anie.200351826  0.557
2003 Nicolaou KC, Li Y, Uesaka N, Koftis TV, Vyskocil S, Ling T, Govindasamy M, Qian W, Bernal F, Chen DY. Total synthesis of the proposed azaspiracid-1 structure, part 1: construction of the enantiomerically pure C1-C20, C21-C27, and C28-C40 fragments. Angewandte Chemie (International Ed. in English). 42: 3643-8. PMID 12916036 DOI: 10.1002/Anie.200351825  0.692
2003 Nicolaou KC, Li Y, Uesaka N, Koftis TV, Vyskocil S, Ling T, Govindasamy M, Qian W, Bernal F, Chen DY. Total Synthesis of the Proposed Azaspiracid-1 Structure (I). Part 1. Construction of the Enantiomerically Pure C1—C20, C21—C27, and C28—C40 Fragments. Cheminform. 34. DOI: 10.1002/chin.200346216  0.5
2001 Nicolaou KC, Li Y, Fylaktakidou KC, Mitchell HJ, Sugita K. Total Synthesis of Apoptolidin: Part 2. Coupling of Key Building Blocks and Completion of the Synthesis. Angewandte Chemie (International Ed. in English). 40: 3854-3857. PMID 29712136 DOI: 10.1002/1521-3773(20011015)40:20<3854::Aid-Anie3854>3.0.Co;2-D  0.687
2001 Nicolaou KC, Li Y, Fylaktakidou KC, Mitchell HJ, Wei HX, Weyershausen B. Total Synthesis of Apoptolidin: Part 1. Retrosynthetic Analysis and Construction of Building Blocks. Angewandte Chemie (International Ed. in English). 40: 3849-3854. PMID 29712121 DOI: 10.1002/1521-3773(20011015)40:20<3849::Aid-Anie3849>3.0.Co;2-M  0.673
2001 Nicolaou KC, Li Y, Fylaktakidou KC, Mitchell HJ, Sugita K. Total Synthesis of Apoptolidin: Part 2. Coupling of Key Building Blocks and Completion of the Synthesis We thank Dr. C. Khosla and Dr. Y. Hayakawa for generous gifts of apoptolidin, and Dr. D. H. Huang and Dr. G. Siuzdak for NMR spectroscopic and mass spectrometric assistance, respectively. This work was financially supported by the National Institutes of Health (USA), the Skaggs Institute for Chemical Biology, American Biosciences, a predoctoral fellowship from Boehringer Ingelheim (to Y.L.), a postdoctoral fellowship the George Hewitt Foundation (to K.C.F.), and grants from Abbott Laboratories, ArrayBiopharma, Bayer, Boehringer Ingelheim, DuPont, Glaxo, Hoffmann-LaRoche, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie (International Ed. in English). 40: 3854-3857. PMID 11668554 DOI: 10.1002/1521-3773(20011015)40:20<3854::AID-ANIE3854>3.0.CO;2-D  0.644
2001 Nicolaou KC, Li Y, Fylaktakidou KC, Mitchell HJ, Wei HX, Weyershausen B. Total Synthesis of Apoptolidin: Part 1. Retrosynthetic Analysis and Construction of Building Blocks We thank Dr. D. H. Huang and Dr. G. Siuzdak for NMR spectroscopic and mass spectrometric assistance, respectively. This work was financially supported by the National Institutes of Health (USA), the Skaggs Institute for Chemical Biology, American Biosciences, a pre-doctoral fellowship from Boehringer Ingelheim (Y.L.), a postdoctoral fellowship the George Hewitt Foundation (K.C.F.), and grants from Abbott Laboratories, ArrayBiopharma, Bayer, Boehringer Ingelheim, DuPont, Glaxo, Hoffmann-LaRoche, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie (International Ed. in English). 40: 3849-3854. PMID 11668553 DOI: 10.1002/1521-3773(20011015)40:20<3849::AID-ANIE3849>3.0.CO;2-M  0.615
2001 Nicolaou KC, Li Y, Fylaktakidou KC, Mitchell HJ, Sugita K. Totalsynthese von Apoptolidin - Teil 2: Verknüpfung der Schlüsselintermediate und Abschluss der Synthese Angewandte Chemie. 113: 3972-3976. DOI: 10.1002/1521-3757(20011015)113:20<3972::Aid-Ange3972>3.0.Co;2-Z  0.625
2001 Nicolaou KC, Li Y, Fylaktakidou KC, Mitchell HJ, Wei H, Weyershausen B. Totalsynthese von Apoptolidin - Teil 1: Retrosynthese und Aufbau von Schlüsselintermediaten Angewandte Chemie. 113: 3968-3972. DOI: 10.1002/1521-3757(20011015)113:20<3968::Aid-Ange3968>3.0.Co;2-1  0.576
2000 Nicolaou KC, Li Y, Weyershausen B, Wei H. Synthesis of the macrocyclic core of apoptolidin Chemical Communications. 307-308. DOI: 10.1039/B000424N  0.502
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