Howard C. Hang, Ph.D. - Publications

Affiliations: 
2003 University of California, Berkeley, Berkeley, CA, United States 
Area:
Bioorthogonal chemistry

102 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Klupt S, Fam KT, Zhang X, Chodisetti PK, Mehmood A, Boyd T, Grotjahn D, Park D, Hang HC. Secreted antigen A peptidoglycan hydrolase is essential for cell separation and priming of immune checkpoint inhibitor cancer therapy. Biorxiv : the Preprint Server For Biology. PMID 38014356 DOI: 10.1101/2023.11.19.567738  0.745
2021 Yang X, Zhang ZJ, Hang HC. Chemical proteomics for identifying short-chain fatty acid modified proteins in Salmonella. Methods in Enzymology. 664: 135-150. PMID 35331371 DOI: 10.1016/bs.mie.2021.11.012  0.54
2020 Tsukidate T, Li Q, Hang HC. Nuclear Receptor Chemical Reporter Enables Domain-Specific Analysis of Ligands in Mammalian Cells. Acs Chemical Biology. PMID 32909738 DOI: 10.1021/Acschembio.0C00432  0.342
2020 Kim B, Espinosa J, Hang HC. Biochemical analysis of NlpC/p60 peptidoglycan hydrolase activity. Methods in Enzymology. 638: 109-127. PMID 32416909 DOI: 10.1016/Bs.Mie.2020.02.017  0.322
2020 Wu X, Spence JS, Das T, Yuan X, Chen C, Zhang Y, Li Y, Sun Y, Chandran K, Hang HC, Peng T. Site-Specific Photo-Crosslinking Proteomics Reveal Regulation of IFITM3 Trafficking and Turnover by VCP/p97 ATPase. Cell Chemical Biology. PMID 32243810 DOI: 10.1016/J.Chembiol.2020.03.004  0.338
2020 Yang X, Forster ER, Darabedian N, Kim AT, Pratt MR, Shen A, Hang HC. Translation of microbiota short-chain fatty acid mechanisms affords anti-infective acyl-salicylic acid derivatives. Acs Chemical Biology. PMID 32091869 DOI: 10.1021/Acschembio.9B01009  0.602
2019 Griffin ME, Hespen CW, Wang YC, Hang HC. Translation of peptidoglycan metabolites into immunotherapeutics. Clinical & Translational Immunology. 8: e1095. PMID 31798878 DOI: 10.1002/Cti2.1095  0.33
2019 Tsukidate T, Li Q, Hang HC. Targeted and proteome-wide analysis of metabolite-protein interactions. Current Opinion in Chemical Biology. 54: 19-27. PMID 31790852 DOI: 10.1016/J.Cbpa.2019.10.008  0.386
2019 Zhang ZJ, Pedicord VA, Peng T, Hang HC. Site-specific acylation of a bacterial virulence regulator attenuates infection. Nature Chemical Biology. PMID 31740807 DOI: 10.1038/S41589-019-0392-5  0.566
2019 Zhang Z, Wang YC, Yang X, Hang HC. Chemical reporters for exploring microbiology and microbiota mechanisms. Chembiochem : a European Journal of Chemical Biology. PMID 31730246 DOI: 10.1002/Cbic.201900535  0.533
2019 Thinon E, Hang HC. Chemical Proteomic Analysis of S-Fatty Acylated Proteins and Their Modification Sites. Methods in Molecular Biology (Clifton, N.J.). 2009: 45-57. PMID 31152394 DOI: 10.1007/978-1-4939-9532-5_4  0.372
2019 Kim B, Wang YC, Hespen CW, Espinosa J, Salje J, Rangan KJ, Oren DA, Kang JY, Pedicord VA, Hang HC. secreted antigen A generates muropeptides to enhance host immunity and limit bacterial pathogenesis. Elife. 8. PMID 30969170 DOI: 10.7554/Elife.45343  0.364
2019 Zhu XG, Nicholson Puthenveedu S, Shen Y, La K, Ozlu C, Wang T, Klompstra D, Gultekin Y, Chi J, Fidelin J, Peng T, Molina H, Hang HC, Min W, Birsoy K. CHP1 Regulates Compartmentalized Glycerolipid Synthesis by Activating GPAT4. Molecular Cell. PMID 30846317 DOI: 10.1016/J.Molcel.2019.01.037  0.419
2019 Wang YC, Westcott NP, Griffin ME, Hang HC. Peptidoglycan metabolite photoaffinity reporters reveal direct binding to intracellular pattern recognition receptors and Arf GTPases. Acs Chemical Biology. PMID 30735346 DOI: 10.1021/Acschembio.8B01038  0.398
2019 Spence JS, He R, Hoffmann HH, Das T, Thinon E, Rice CM, Peng T, Chandran K, Hang HC. IFITM3 directly engages and shuttles incoming virus particles to lysosomes. Nature Chemical Biology. PMID 30643282 DOI: 10.1038/S41589-018-0213-2  0.386
2019 Li Q, Hang H. Abstract B064: Chemical biology studies of anti-inflammatory lipids Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-B064  0.34
2018 Peng T, Hang HC. Chemical Proteomic Profiling of Protein Fatty-Acylation in Microbial Pathogens. Current Topics in Microbiology and Immunology. PMID 30128826 DOI: 10.1007/82_2018_126  0.412
2018 Liu W, Zhou Y, Peng T, Zhou P, Ding X, Li Z, Zhong H, Xu Y, Chen S, Hang HC, Shao F. N-fatty acylation of multiple membrane-associated proteins by Shigella IcsB effector to modulate host function. Nature Microbiology. PMID 30061757 DOI: 10.1038/S41564-018-0215-6  0.407
2018 Thinon E, Fernandez JP, Molina H, Hang HC. Selective enrichment and direct analysis of protein S-palmitoylation sites. Journal of Proteome Research. PMID 29575903 DOI: 10.1021/Acs.Jproteome.8B00002  0.392
2018 Garst EH, Percher A, Hoang H, Hang H. Structural and Functional Studies of Antiviral Protein IFITM3 Biophysical Journal. 114: 424a-425a. DOI: 10.1016/J.Bpj.2017.11.2353  0.303
2017 McMichael TM, Zhang L, Chemudupati M, Hach JC, Kenney AD, Hang HC, Yount JS. The palmitoyltransferase ZDHHC20 enhances interferon-induced transmembrane protein 3 (IFITM3) palmitoylation and antiviral activity. The Journal of Biological Chemistry. PMID 29079573 DOI: 10.1074/Jbc.M117.800482  0.382
2017 Rangan KJ, Hang HC. Biochemical Mechanisms of Pathogen Restriction by Intestinal Bacteria. Trends in Biochemical Sciences. PMID 28927699 DOI: 10.1016/J.Tibs.2017.08.005  0.318
2017 Percher A, Thinon E, Hang H. Mass-Tag Labeling Using Acyl-PEG Exchange for the Determination of Endogenous Protein S-Fatty Acylation. Current Protocols in Protein Science. 89: 14.17.1-14.17.11. PMID 28762493 DOI: 10.1002/Cpps.36  0.384
2017 Tsou LK, Yount JS, Hang HC. Epigallocatechin-3-gallate inhibits bacterial virulence and invasion of host cells. Bioorganic & Medicinal Chemistry. PMID 28325635 DOI: 10.1016/J.Bmc.2017.03.023  0.352
2017 Zhang MM, Hang HC. Protein S-palmitoylation in cellular differentiation. Biochemical Society Transactions. 45: 275-285. PMID 28202682 DOI: 10.1042/Bst20160236  0.373
2017 Westcott NP, Fernandez JP, Molina H, Hang HC. Chemical proteomics reveals ADP-ribosylation of small GTPases during oxidative stress. Nature Chemical Biology. PMID 28092360 DOI: 10.1038/Nchembio.2280  0.379
2016 Peng T, Hang HC. Site-Specific Bioorthogonal Labeling for Fluorescence Imaging of Intracellular Proteins in Living Cells. Journal of the American Chemical Society. PMID 27768298 DOI: 10.1021/Jacs.6B08733  0.408
2016 Rangan KJ, Pedicord VA, Wang YC, Kim B, Lu Y, Shaham S, Mucida D, Hang HC. A secreted bacterial peptidoglycan hydrolase enhances tolerance to enteric pathogens. Science (New York, N.Y.). 353: 1434-1437. PMID 27708039 DOI: 10.1126/Science.Aaf3552  0.311
2016 Thinon E, Percher A, Hang HC. Bioorthogonal Chemical Reporters for Monitoring Unsaturated Fatty-Acylated Proteins. Chembiochem : a European Journal of Chemical Biology. PMID 27350074 DOI: 10.1002/Cbic.201600213  0.394
2016 Percher A, Ramakrishnan S, Thinon E, Yuan X, Yount JS, Hang HC. Mass-tag labeling reveals site-specific and endogenous levels of protein S-fatty acylation. Proceedings of the National Academy of Sciences of the United States of America. PMID 27044110 DOI: 10.1073/Pnas.1602244113  0.419
2016 Tsou LK, Lara-Tejero M, RoseFigura J, Zhang ZJ, Wang YC, Yount JS, Lefebre M, Dossa PD, Kato J, Guan F, Lam W, Cheng YC, Galan JE, Hang HC. Anti-bacterial flavonoids from medicinal plants covalently inactivate type III protein secretion substrates. Journal of the American Chemical Society. PMID 26847396 DOI: 10.1021/Jacs.5B11575  0.548
2016 Thinon E, Percher A, Hang HC. Inside Cover: Bioorthogonal Chemical Reporters for Monitoring Unsaturated Fatty-Acylated Proteins (ChemBioChem 19/2016) Chembiochem. 17: 1787-1787. DOI: 10.1002/Cbic.201600500  0.359
2015 Peng T, Thinon E, Hang HC. Proteomic analysis of fatty-acylated proteins. Current Opinion in Chemical Biology. 30: 77-86. PMID 26656971 DOI: 10.1016/J.Cbpa.2015.11.008  0.397
2015 Santiago-Tirado FH, Peng T, Yang M, Hang HC, Doering TL. A Single Protein S-acyl Transferase Acts through Diverse Substrates to Determine Cryptococcal Morphology, Stress Tolerance, and Pathogenic Outcome. Plos Pathogens. 11: e1004908. PMID 25970403 DOI: 10.1371/Journal.Ppat.1004908  0.404
2015 Thinon E, Hang HC. Chemical reporters for exploring protein acylation. Biochemical Society Transactions. 43: 253-61. PMID 25849926 DOI: 10.1042/Bst20150004  0.432
2015 Moudgil DK, Westcott N, Famulski JK, Patel K, Macdonald D, Hang H, Chan GK. A novel role of farnesylation in targeting a mitotic checkpoint protein, human Spindly, to kinetochores. The Journal of Cell Biology. 208: 881-96. PMID 25825516 DOI: 10.1083/Jcb.201412085  0.323
2015 Burnaevskiy N, Peng T, Reddick LE, Hang HC, Alto NM. Myristoylome profiling reveals a concerted mechanism of ARF GTPase deacylation by the bacterial protease IpaJ. Molecular Cell. 58: 110-22. PMID 25773595 DOI: 10.1016/J.Molcel.2015.01.040  0.458
2015 Yu X, Decker KB, Barker K, Neunuebel MR, Saul J, Graves M, Westcott N, Hang H, LaBaer J, Qiu J, Machner MP. Host-pathogen interaction profiling using self-assembling human protein arrays. Journal of Proteome Research. 14: 1920-36. PMID 25739981 DOI: 10.1021/Pr5013015  0.396
2015 Peng T, Hang HC. Bifunctional fatty acid chemical reporter for analyzing S-palmitoylated membrane protein-protein interactions in mammalian cells. Journal of the American Chemical Society. 137: 556-9. PMID 25575299 DOI: 10.1021/Ja502109N  0.407
2015 Liu Z, Yang T, Li X, Peng T, Hang HC, Li XD. Integrative chemical biology approaches for identification and characterization of "erasers" for fatty-acid-acylated lysine residues within proteins. Angewandte Chemie (International Ed. in English). 54: 1149-52. PMID 25476551 DOI: 10.1002/Anie.201408763  0.384
2014 Westcott NP, Hang HC. Chemical reporters for exploring ADP-ribosylation and AMPylation at the host-pathogen interface. Current Opinion in Chemical Biology. 23: 56-62. PMID 25461386 DOI: 10.1016/J.Cbpa.2014.10.002  0.385
2014 Chesarino NM, Hach JC, Chen JL, Zaro BW, Rajaram MV, Turner J, Schlesinger LS, Pratt MR, Hang HC, Yount JS. Chemoproteomics reveals Toll-like receptor fatty acylation. Bmc Biology. 12: 91. PMID 25371237 DOI: 10.1186/S12915-014-0091-3  0.628
2014 Peng T, Yuan X, Hang HC. Turning the spotlight on protein-lipid interactions in cells. Current Opinion in Chemical Biology. 21: 144-53. PMID 25129056 DOI: 10.1016/J.Cbpa.2014.07.015  0.361
2014 Yu X, Woolery AR, Luong P, Hao YH, Grammel M, Westcott N, Park J, Wang J, Bian X, Demirkan G, Hang HC, Orth K, LaBaer J. Copper-catalyzed azide-alkyne cycloaddition (click chemistry)-based detection of global pathogen-host AMPylation on self-assembled human protein microarrays. Molecular & Cellular Proteomics : McP. 13: 3164-76. PMID 25073739 DOI: 10.1074/Mcp.M114.041103  0.397
2014 Peng T, Hang HC. SORTing out cellular proteomes in vivo. Nature Biotechnology. 32: 445-6. PMID 24811517 DOI: 10.1038/Nbt.2898  0.416
2013 Tsou LK, Dossa PD, Hang HC. Small molecules aimed at type III secretion systems to inhibit bacterial virulence. Medchemcomm. 4: 68-79. PMID 23930198 DOI: 10.1039/C2Md20213A  0.325
2013 Grammel M, Hang HC. Chemical reporters for biological discovery. Nature Chemical Biology. 9: 475-84. PMID 23868317 DOI: 10.1038/Nchembio.1296  0.394
2013 Zhang MM, Wu PY, Kelly FD, Nurse P, Hang HC. Quantitative control of protein S-palmitoylation regulates meiotic entry in fission yeast. Plos Biology. 11: e1001597. PMID 23843742 DOI: 10.1371/Journal.Pbio.1001597  0.399
2013 Charron G, Li MM, MacDonald MR, Hang HC. Prenylome profiling reveals S-farnesylation is crucial for membrane targeting and antiviral activity of ZAP long-isoform. Proceedings of the National Academy of Sciences of the United States of America. 110: 11085-90. PMID 23776219 DOI: 10.1073/Pnas.1302564110  0.412
2013 Jiang H, Khan S, Wang Y, Charron G, He B, Sebastian C, Du J, Kim R, Ge E, Mostoslavsky R, Hang HC, Hao Q, Lin H. SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine. Nature. 496: 110-3. PMID 23552949 DOI: 10.1038/Nature12038  0.398
2013 Grammel M, Hang HC. Identification of lysine acetyltransferase substrates using bioorthogonal chemical proteomics. Methods in Molecular Biology (Clifton, N.J.). 981: 201-10. PMID 23381864 DOI: 10.1007/978-1-62703-305-3_16  0.379
2013 Yount JS, Zhang MM, Hang HC. Emerging roles for protein S-palmitoylation in immunity from chemical proteomics. Current Opinion in Chemical Biology. 17: 27-33. PMID 23332315 DOI: 10.1016/J.Cbpa.2012.11.008  0.367
2013 Zaro BW, Hang HC, Pratt MR. Incorporation of unnatural sugars for the identification of glycoproteins. Methods in Molecular Biology (Clifton, N.J.). 951: 57-67. PMID 23296524 DOI: 10.1007/978-1-62703-146-2_5  0.632
2013 Hang HC, Pratt MR. Molecular Probes for Protein Glycosylation Reference Module in Chemistry, Molecular Sciences and Chemical Engineering. DOI: 10.1016/B978-0-12-409547-2.02835-3  0.541
2012 Zhang X, Abreu JG, Yokota C, MacDonald BT, Singh S, Coburn KL, Cheong SM, Zhang MM, Ye QZ, Hang HC, Steen H, He X. Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation. Cell. 149: 1565-77. PMID 22726442 DOI: 10.1016/J.Cell.2012.04.039  0.357
2012 Yount JS, Karssemeijer RA, Hang HC. S-palmitoylation and ubiquitination differentially regulate interferon-induced transmembrane protein 3 (IFITM3)-mediated resistance to influenza virus. The Journal of Biological Chemistry. 287: 19631-41. PMID 22511783 DOI: 10.1074/Jbc.M112.362095  0.344
2012 Grammel M, Dossa PD, Taylor-Salmon E, Hang HC. Cell-selective labeling of bacterial proteomes with an orthogonal phenylalanine amino acid reporter. Chemical Communications (Cambridge, England). 48: 1473-4. PMID 22080199 DOI: 10.1039/C1Cc14939C  0.361
2012 Yount JS, Charron G, Hang HC. Bioorthogonal proteomics of 15-hexadecynyloxyacetic acid chemical reporter reveals preferential targeting of fatty acid modified proteins and biosynthetic enzymes. Bioorganic & Medicinal Chemistry. 20: 650-4. PMID 21524915 DOI: 10.1016/J.Bmc.2011.03.062  0.431
2011 Yount JS, Zhang MM, Hang HC. Visualization and Identification of Fatty Acylated Proteins Using Chemical Reporters. Current Protocols in Chemical Biology. 3: 65-79. PMID 23061028 DOI: 10.1002/9780470559277.Ch100225  0.436
2011 Grammel M, Luong P, Orth K, Hang HC. A chemical reporter for protein AMPylation. Journal of the American Chemical Society. 133: 17103-5. PMID 21942216 DOI: 10.1021/Ja205137D  0.424
2011 Agüera-González S, Gross CC, Fernández-Messina L, Ashiru O, Esteso G, Hang HC, Reyburn HT, Long EO, Valés-Gómez M. Palmitoylation of MICA, a ligand for NKG2D, mediates its recruitment to membrane microdomains and promotes its shedding. European Journal of Immunology. 41: 3667-76. PMID 21928280 DOI: 10.1002/Eji.201141645  0.358
2011 Hang HC, Linder ME. Exploring protein lipidation with chemical biology. Chemical Reviews. 111: 6341-58. PMID 21919527 DOI: 10.1021/Cr2001977  0.404
2011 Hicks SW, Charron G, Hang HC, Galán JE. Subcellular targeting of Salmonella virulence proteins by host-mediated S-palmitoylation. Cell Host & Microbe. 10: 9-20. PMID 21767808 DOI: 10.1016/J.Chom.2011.06.003  0.417
2011 Hang HC, Wilson JP, Charron G. Bioorthogonal chemical reporters for analyzing protein lipidation and lipid trafficking. Accounts of Chemical Research. 44: 699-708. PMID 21675729 DOI: 10.1021/Ar200063V  0.367
2011 Zaro BW, Yang YY, Hang HC, Pratt MR. Chemical reporters for fluorescent detection and identification of O-GlcNAc-modified proteins reveal glycosylation of the ubiquitin ligase NEDD4-1 Proceedings of the National Academy of Sciences of the United States of America. 108: 8146-8151. PMID 21540332 DOI: 10.1073/Pnas.1102458108  0.64
2011 Yang YY, Hang HC. Chemical approaches for the detection and synthesis of acetylated proteins. Chembiochem : a European Journal of Chemical Biology. 12: 314-22. PMID 21243719 DOI: 10.1002/Cbic.201000558  0.329
2011 Charron G, Tsou LK, Maguire W, Yount JS, Hang HC. Alkynyl-farnesol reporters for detection of protein S-prenylation in cells. Molecular Biosystems. 7: 67-73. PMID 21107478 DOI: 10.1039/C0Mb00183J  0.407
2011 Wilson JP, Raghavan AS, Yang YY, Charron G, Hang HC. Proteomic analysis of fatty-acylated proteins in mammalian cells with chemical reporters reveals S-acylation of histone H3 variants. Molecular & Cellular Proteomics : McP. 10: M110.001198. PMID 21076176 DOI: 10.1074/Mcp.M110.001198  0.367
2010 Yang YY, Grammel M, Raghavan AS, Charron G, Hang HC. Comparative analysis of cleavable azobenzene-based affinity tags for bioorthogonal chemical proteomics. Chemistry & Biology. 17: 1212-22. PMID 21095571 DOI: 10.1016/J.Chembiol.2010.09.012  0.42
2010 Ivanov SS, Charron G, Hang HC, Roy CR. Lipidation by the host prenyltransferase machinery facilitates membrane localization of Legionella pneumophila effector proteins. The Journal of Biological Chemistry. 285: 34686-98. PMID 20813839 DOI: 10.1074/Jbc.M110.170746  0.373
2010 Grammel M, Zhang MM, Hang HC. Orthogonal alkynyl amino acid reporter for selective labeling of bacterial proteomes during infection. Angewandte Chemie (International Ed. in English). 49: 5970-4. PMID 20632346 DOI: 10.1002/Anie.201002050  0.357
2010 Yount JS, Moltedo B, Yang YY, Charron G, Moran TM, López CB, Hang HC. Palmitoylome profiling reveals S-palmitoylation-dependent antiviral activity of IFITM3. Nature Chemical Biology. 6: 610-4. PMID 20601941 DOI: 10.1038/Nchembio.405  0.365
2010 Yount JS, Tsou LK, Dossa PD, Kullas AL, van der Velden AW, Hang HC. Visible fluorescence detection of type III protein secretion from bacterial pathogens. Journal of the American Chemical Society. 132: 8244-5. PMID 20504019 DOI: 10.1021/Ja102257V  0.385
2010 Zhang MM, Tsou LK, Charron G, Raghavan AS, Hang HC. Tandem fluorescence imaging of dynamic S-acylation and protein turnover. Proceedings of the National Academy of Sciences of the United States of America. 107: 8627-32. PMID 20421494 DOI: 10.1073/Pnas.0912306107  0.395
2010 Rangan KJ, Yang YY, Charron G, Hang HC. Rapid visualization and large-scale profiling of bacterial lipoproteins with chemical reporters. Journal of the American Chemical Society. 132: 10628-9. PMID 20230003 DOI: 10.1021/Ja101387B  0.399
2010 Yang YY, Ascano JM, Hang HC. Bioorthogonal chemical reporters for monitoring protein acetylation. Journal of the American Chemical Society. 132: 3640-1. PMID 20192265 DOI: 10.1021/Ja908871T  0.435
2009 Tsou LK, Zhang MM, Hang HC. Clickable fluorescent dyes for multimodal bioorthogonal imaging. Organic & Biomolecular Chemistry. 7: 5055-8. PMID 20024096 DOI: 10.1039/B917119N  0.301
2009 Charron G, Wilson J, Hang HC. Chemical tools for understanding protein lipidation in eukaryotes. Current Opinion in Chemical Biology. 13: 382-91. PMID 19699139 DOI: 10.1016/J.Cbpa.2009.07.010  0.382
2009 Charron G, Zhang MM, Yount JS, Wilson J, Raghavan AS, Shamir E, Hang HC. Robust fluorescent detection of protein fatty-acylation with chemical reporters. Journal of the American Chemical Society. 131: 4967-75. PMID 19281244 DOI: 10.1021/Ja810122F  0.415
2009 Raghavan AS, Hang HC. Seeing small molecules in action with bioorthogonal chemistry. Drug Discovery Today. 14: 178-84. PMID 18973827 DOI: 10.1016/J.Drudis.2008.09.014  0.367
2008 Raghavan A, Charron G, Flexner J, Hang HC. Chemical probes for profiling fatty acid-associated proteins in living cells. Bioorganic & Medicinal Chemistry Letters. 18: 5982-6. PMID 18929483 DOI: 10.1016/J.Bmcl.2008.09.083  0.42
2008 Ching W, Hang HC, Nusse R. Lipid-independent secretion of a Drosophila Wnt protein. The Journal of Biological Chemistry. 283: 17092-8. PMID 18430724 DOI: 10.1074/Jbc.M802059200  0.369
2008 Tian E, Ten Hagen KG, Shum L, Hang HC, Imbert Y, Young WW, Bertozzi CR, Tabak LA. An inhibitor of O-glycosylation induces apoptosis in NIH3T3 cells and developing mouse embryonic mandibular tissues. The Journal of Biological Chemistry. 283: 4460. PMID 18348354  0.396
2008 Costantino CM, Hang HC, Kent SC, Hafler DA, Ploegh HL. Lysosomal cysteine and aspartic proteases are heterogeneously expressed and act redundantly to initiate human invariant chain degradation. Journal of Immunology (Baltimore, Md. : 1950). 180: 2876-85. PMID 18292509 DOI: 10.4049/Jimmunol.180.5.2876  0.449
2007 Hang HC, Geutjes EJ, Grotenbreg G, Pollington AM, Bijlmakers MJ, Ploegh HL. Chemical probes for the rapid detection of Fatty-acylated proteins in Mammalian cells. Journal of the American Chemical Society. 129: 2744-5. PMID 17305342 DOI: 10.1021/Ja0685001  0.564
2007 Costanti-England C, Hang H, Hafler D, Ploegh H. Haplotype-specific Use of Lysosomal Proteases Can Modulate the Class II MHC Peptide Repertoire but Does Not Impair Invariant Chain Degradation in Human Antigen Presenting Cells Clinical Immunology. 123: S53. DOI: 10.1016/J.Clim.2007.03.330  0.454
2006 Hang HC, Loureiro J, Spooner E, van der Velden AW, Kim YM, Pollington AM, Maehr R, Starnbach MN, Ploegh HL. Mechanism-based probe for the analysis of cathepsin cysteine proteases in living cells. Acs Chemical Biology. 1: 713-23. PMID 17184136 DOI: 10.1021/Cb600431A  0.722
2005 Hang HC, Bertozzi CR. The chemistry and biology of mucin-type O-linked glycosylation. Bioorganic & Medicinal Chemistry. 13: 5021-34. PMID 16005634 DOI: 10.1016/J.Bmc.2005.04.085  0.5
2005 Maehr R, Hang HC, Mintern JD, Kim YM, Cuvillier A, Nishimura M, Yamada K, Shirahama-Noda K, Hara-Nishimura I, Ploegh HL. Asparagine endopeptidase is not essential for class II MHC antigen presentation but is required for processing of cathepsin L in mice. Journal of Immunology (Baltimore, Md. : 1950). 174: 7066-74. PMID 15905550 DOI: 10.4049/Jimmunol.174.11.7066  0.675
2004 Hang HC, Ploegh H. Catching proteases in action with microarrays. Chemistry & Biology. 11: 1328-30. PMID 15489158 DOI: 10.1016/J.Chembiol.2004.09.005  0.454
2004 Tian E, Ten Hagen KG, Shum L, Hang HC, Imbert Y, Young WW, Bertozzi CR, Tabak LA. An inhibitor of O-glycosylation induces apoptosis in NIH3T3 cells and developing mouse embryonic mandibular tissues. The Journal of Biological Chemistry. 279: 50382-90. PMID 15342645 DOI: 10.1074/Jbc.M406397200  0.518
2004 Pratt MR, Hang HC, Ten Hagen KG, Rarick J, Gerken TA, Tabak LA, Bertozzi CR. Deconvoluting the functions of polypeptide N-alpha-acetylgalactosaminyltransferase family members by glycopeptide substrate profiling. Chemistry & Biology. 11: 1009-16. PMID 15271359 DOI: 10.1016/J.Chembiol.2004.05.009  0.656
2004 Hang HC, Yu C, Ten Hagen KG, Tian E, Winans KA, Tabak LA, Bertozzi CR. Small molecule inhibitors of mucin-type O-linked glycosylation from a uridine-based library. Chemistry & Biology. 11: 337-45. PMID 15123263 DOI: 10.1016/J.Chembiol.2004.02.023  0.757
2004 Hang HC, Yu C, Pratt MR, Bertozzi CR. Probing glycosyltransferase activities with the Staudinger ligation. Journal of the American Chemical Society. 126: 6-7. PMID 14709032 DOI: 10.1021/Ja037692M  0.647
2003 Hang HC, Yu C, Kato DL, Bertozzi CR. A metabolic labeling approach toward proteomic analysis of mucin-type O-linked glycosylation. Proceedings of the National Academy of Sciences of the United States of America. 100: 14846-51. PMID 14657396 DOI: 10.1073/Pnas.2335201100  0.543
2003 Wojczyk BS, Stwora-Wojczyk MM, Hagen FK, Striepen B, Hang HC, Bertozzi CR, Roos DS, Spitalnik SL. cDNA cloning and expression of UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase T1 from Toxoplasma gondii. Molecular and Biochemical Parasitology. 131: 93-107. PMID 14511808 DOI: 10.1016/S0166-6851(03)00196-8  0.51
2003 Luchansky SJ, Hang HC, Saxon E, Grunwell JR, Yu C, Dube DH, Bertozzi CR. Constructing azide-labeled cell surfaces using polysaccharide biosynthetic pathways. Methods in Enzymology. 362: 249-72. PMID 12968369 DOI: 10.1016/S0076-6879(03)01018-8  0.708
2003 Vocadlo DJ, Hang HC, Kim EJ, Hanover JA, Bertozzi CR. A chemical approach for identifying O-GlcNAc-modified proteins in cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 9116-21. PMID 12874386 DOI: 10.1073/Pnas.1632821100  0.576
2002 Saxon E, Luchansky SJ, Hang HC, Yu C, Lee SC, Bertozzi CR. Investigating cellular metabolism of synthetic azidosugars with the Staudinger ligation. Journal of the American Chemical Society. 124: 14893-902. PMID 12475330 DOI: 10.1021/Ja027748X  0.759
2001 Jacobs CL, Goon S, Yarema KJ, Hinderlich S, Hang HC, Chai DH, Bertozzi CR. Substrate specificity of the sialic acid biosynthetic pathway. Biochemistry. 40: 12864-74. PMID 11669623 DOI: 10.1021/Bi010862S  0.76
2001 Hang HC, Bertozzi CR. Chemoselective approaches to glycoprotein assembly. Accounts of Chemical Research. 34: 727-36. PMID 11560472 DOI: 10.1021/Ar9901570  0.474
2001 Hang HC, Bertozzi CR. Ketone isosteres of 2-N-acetamidosugars as substrates for metabolic cell surface engineering. Journal of the American Chemical Society. 123: 1242-3. PMID 11456684 DOI: 10.1021/Ja002962B  0.588
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