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Jonathan A. Winger, Ph.D. - Publications

Affiliations: 
2004 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
catalytic and biological properties of redox enzymes
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23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Boehme J, Le Moan N, Kameny RJ, Loucks A, Johengen MJ, Lesneski AL, Gong W, Goudy BD, Davis T, Tanaka K, Davis A, He Y, Long-Boyle J, Ivaturi V, Gobburu JVS, ... Winger JA, et al. Correction: Preservation of myocardial contractility during acute hypoxia with OMX-CV, a novel oxygen delivery biotherapeutic. Plos Biology. 17: e3000119. PMID 30677022 DOI: 10.1371/Journal.Pbio.3000119  0.7
2018 Boehme J, Le Moan N, Kameny RJ, Loucks A, Johengen MJ, Lesneski AL, Gong W, Davis T, Tanaka K, Davis A, He Y, Long-Boyle J, Ivaturi V, Gobburu JVS, Winger JA, et al. Preservation of myocardial contractility during acute hypoxia with OMX-CV, a novel oxygen delivery biotherapeutic. Plos Biology. 16: e2005924. PMID 30335746 DOI: 10.1371/Journal.Pbio.2005924  0.716
2018 Moan NL, Leung P, Ng S, Davis T, Liang C, Winger J, Cary SP, Butowski N, Krtolica A. Abstract 4726A: The oxygen carrier omx restores antitumor immunity and cures tumors as a single agent or in combination with checkpoint inhibitors in an intracranial glioblastoma mouse model Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-4726A  0.752
2018 Leong KG, Pan Y, Guo C, Narayanan P, Winger JA, Cary SP, Moan NL, Krtolica A. Abstract 1744: Reversal of advanced colitis-associated colon cancer by OMX, a novel oxygen carrier that immunosensitizes the hypoxic tumor microenvironment Immunology. 78: 1744-1744. DOI: 10.1158/1538-7445.Am2018-1744  0.753
2018 Le Moan N, Davis T, Leung P, Ng S, Winger J, Cary S, Butowski N, Krtolica A. TMIC-15. OMX IS A TUMOR MICROENVIRONMENT MODIFIER THAT RESTORES ANTI-TUMOR IMMUNITY AND IMPROVES ANTI-TUMOR EFFICACY BY REDUCING TUMOR HYPOXIA IN INTRACRANIAL GLIOBLASTOMA MOUSE MODEL Neuro-Oncology. 20: vi259-vi259. DOI: 10.1093/Neuonc/Noy148.1074  0.737
2017 Leong KG, Pan Y, Winger JA, Cary SP, Moan NL, Krtolica A. Abstract 1627: Enhancement of anti-cancer immunity by OMX, a novel oxygen carrier immunotherapeutic that ameliorates the hypoxic tumor microenvironment Cancer Research. 77: 1627-1627. DOI: 10.1158/1538-7445.Am2017-1627  0.751
2016 Visperas PR, Wilson CG, Winger JA, Yan Q, Lin K, Arkin MR, Weiss A, Kuriyan J. Identification of Inhibitors of the Association of ZAP-70 with the T Cell Receptor by High-Throughput Screen. Journal of Biomolecular Screening. PMID 27932698 DOI: 10.1177/1087057116681407  0.702
2016 Krtolica A, Moan NL, Leung P, Seo Y, Winger J, Brocklin HV, Kent M, Cary S. Abstract 2790: Sensitizing the hypoxic tumor microenvironment with OMX, a breakthrough oxygen delivery protein: From protein engineering to clinical trial Cancer Research. 76: 2790-2790. DOI: 10.1158/1538-7445.Am2016-2790  0.728
2016 Moan NL, Leung P, Bedard C, Ng S, Davis T, Liang C, Leong K, Tanaka K, Keating T, Butowski N, Winger J, Cary S, Krtolica A. IMST-52. OMX, AN IND-STAGE BROAD-ACTING OXYGEN CARRIER, IMMUNOSENSITIZES THE TUMOR MICROENVIRONMENT AND PROMOTES EFFECTOR T CELL RESPONSES IN THE GL261 INTRACRANIAL SYNGENEIC GLIOBLASTOMA MODEL Neuro-Oncology. 18: vi98-vi98. DOI: 10.1093/Neuonc/Now212.408  0.749
2015 Visperas PR, Winger JA, Horton TM, Shah NH, Aum DJ, Tao A, Barros T, Yan Q, Wilson CG, Arkin MR, Weiss A, Kuriyan J. Modification by covalent reaction or oxidation of cysteine residues in the tandem-SH2 domains of ZAP-70 and Syk can block phosphopeptide binding. The Biochemical Journal. 465: 149-61. PMID 25287889 DOI: 10.1042/Bj20140793  0.697
2015 Krtolica A, Moan NL, Getz J, Davis T, Ng S, Bedard C, Davis A, Leung P, Serwer L, Tanaka K, Keating T, Yan F, Guerrero T, Kent M, Dickinson P, ... Winger J, et al. Abstract 3003: OMX-4.80P, a novel H-NOX oxygen carrier that oxygenates hypoxic tumors in multiple tumor models and canine cancer patients, downregulates HIF-1 pathway and increases response to radiation therapy leading to cures Cancer Research. 75: 3003-3003. DOI: 10.1158/1538-7445.Am2015-3003  0.406
2015 Serwer L, Le Moan N, Regan M, Blecha J, Davis A, Tanaka K, Keating T, Romero J, Leung P, Davis T, Bedard C, Ng S, Yan F, Santos R, Ozawa T, ... ... Winger J, et al. NIMG-45REAL-TIME PET IMAGING DEMONSTRATES TUMOR ACCUMULATION AND OXYGENATION BY OMX-4.80P, AN OXYGEN CARRIER ENGINEERED FOR THE TREATMENT OF GLIOBLASTOMA Neuro-Oncology. 17: v164.1-v164. DOI: 10.1093/Neuonc/Nov225.45  0.743
2015 Leung P, Le Moan N, Getz J, Ng S, Bedard C, Davis T, Liang C, Davis A, Serwer L, Tanaka K, Keating T, Yan F, Winger J, Sturges B, Guerrero T, et al. ATPS-49RESULTS OF A PHASE 0 CLINICAL TRIAL IN CANINE BRAIN CANCER EVALUATING SAFETY AND ACTIVITY OF OMX-4.80P, A PROTEIN OXYGEN CARRIER IND CANDIDATE FOR TREATMENT OF GLIOBLASTOMA Neuro-Oncology. 17: v29.1-v29. DOI: 10.1093/Neuonc/Nov204.49  0.747
2014 Le Moan N, Getz J, Ng S, Davis T, Bedard C, Davis A, Leung P, Serwer L, Tanaka K, Keating T, Yan F, Winger J, Cary S, Krtolica A. ET-32 * HYPOXIA REDUCTION IN INTRACRANIAL GLIOBLASTOMA MODELS BY OMX-4.80P, A PEGylated ENGINEERED H-NOX OXYGEN CARRIER THAT IS LONG-LASTING IN CIRCULATION AND SAFE Neuro-Oncology. 16: v86-v86. DOI: 10.1093/Neuonc/Nou255.32  0.741
2014 Krtolica A, Le Moan N, Getz J, Davis T, Ng S, Bedard C, Davis A, Leung P, Serwer L, Tanaka K, Keating T, Yan F, Winger J, Cary S. ET-31 * RADIOSENSITIZATION BY OMX-4.80P, A PEGylated H-NOX OXYGEN CARRIER THAT PENETRATES AND OXYGENATES HYPOXIC TUMORS, IN PRECLINICAL MODELS OF GLIOBLASTOMA AND OTHER HYPOXIC CANCERS Neuro-Oncology. 16: v86-v86. DOI: 10.1093/Neuonc/Nou255.31  0.75
2009 Winger JA, Hantschel O, Superti-Furga G, Kuriyan J. The structure of the leukemia drug imatinib bound to human quinone reductase 2 (NQO2) Bmc Structural Biology. 9. PMID 19236722 DOI: 10.1186/1472-6807-9-7  0.575
2008 Winger JA, Derbyshire ER, Lamers MH, Marletta MA, Kuriyan J. The crystal structure of the catalytic domain of a eukaryotic guanylate cyclase. Bmc Structural Biology. 8: 42. PMID 18842118 DOI: 10.1186/1472-6807-8-42  0.749
2007 Winger JA, Derbyshire ER, Marletta MA. Dissociation of nitric oxide from soluble guanylate cyclase and heme-nitric oxide/oxygen binding domain constructs. The Journal of Biological Chemistry. 282: 897-907. PMID 17098738 DOI: 10.1074/Jbc.M606327200  0.708
2007 Boon EM, Cary SP, Huang SH, Winger JA, Derbyshire ER, Price MS, Erbil WK, Marletta MA. Molecular steps in sGC activation Bmc Pharmacology. 7: S27. DOI: 10.1186/1471-2210-7-S1-S27  0.704
2006 Cary SP, Winger JA, Derbyshire ER, Marletta MA. Nitric oxide signaling: no longer simply on or off. Trends in Biochemical Sciences. 31: 231-9. PMID 16530415 DOI: 10.1016/J.Tibs.2006.02.003  0.772
2005 Cary SP, Winger JA, Marletta MA. Tonic and acute nitric oxide signaling through soluble guanylate cyclase is mediated by nonheme nitric oxide, ATP, and GTP. Proceedings of the National Academy of Sciences of the United States of America. 102: 13064-9. PMID 16131543 DOI: 10.1073/Pnas.0506289102  0.77
2005 Winger JA, Marletta MA. Expression and characterization of the catalytic domains of soluble guanylate cyclase: interaction with the heme domain. Biochemistry. 44: 4083-90. PMID 15751985 DOI: 10.1021/Bi047601D  0.531
2005 Boon EM, Cary SP, Huang SH, Winger JA, Marletta MA. Molecular steps in soluble guanylate cyclase activation Bmc Pharmacology. 5: S1. DOI: 10.1186/1471-2210-5-S1-S1  0.762
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