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Richard Keep - Publications

Affiliations: 
2001-2006 University of Michigan, Ann Arbor, Ann Arbor, MI 
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59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Wan Y, Holste KG, Hua Y, Keep RF, Xi G. Brain edema formation and therapy after intracerebral hemorrhage. Neurobiology of Disease. 176: 105948. PMID 36481437 DOI: 10.1016/j.nbd.2022.105948  0.301
2021 Toyota Y, Shishido H, Ye F, Koch LG, Britton SL, Garton HJL, Keep RF, Xi G, Hua Y. Hydrocephalus Following Experimental Subarachnoid Hemorrhage in Rats with Different Aerobic Capacity. International Journal of Molecular Sciences. 22. PMID 33925787 DOI: 10.3390/ijms22094489  0.316
2020 Ye F, Garton HJL, Hua Y, Keep RF, Xi G. The Role of Thrombin in Brain Injury After Hemorrhagic and Ischemic Stroke. Translational Stroke Research. PMID 32989665 DOI: 10.1007/s12975-020-00855-4  0.319
2020 Tan X, Chen J, Keep RF, Xi G, Hua Y. Prx2 (Peroxiredoxin 2) as a Cause of Hydrocephalus After Intraventricular Hemorrhage. Stroke. STROKEAHA119028672. PMID 32279622 DOI: 10.1161/STROKEAHA.119.028672  0.313
2019 Bian L, Zhang J, Wang M, Keep RF, Xi G, Hua Y. Intracerebral Hemorrhage-Induced Brain Injury in Rats: the Role of Extracellular Peroxiredoxin 2. Translational Stroke Research. PMID 31273681 DOI: 10.1007/s12975-019-00714-x  0.345
2018 Liu H, Hua Y, Keep RF, Xi G. Brain Ceruloplasmin Expression After Experimental Intracerebral Hemorrhage and Protection Against Iron-Induced Brain Injury. Translational Stroke Research. PMID 30315404 DOI: 10.1007/s12975-018-0669-0  0.311
2018 Dai S, Hua Y, Keep RF, Novakovic N, Fei Z, Xi G. Minocycline attenuates brain injury and iron overload after intracerebral hemorrhage in aged female rats. Neurobiology of Disease. PMID 29879529 DOI: 10.1016/j.nbd.2018.06.001  0.312
2015 Ni W, Zheng M, Xi G, Keep RF, Hua Y. Role of lipocalin-2 in brain injury after intracerebral hemorrhage. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 25853903 DOI: 10.1038/jcbfm.2015.52  0.315
2014 Gao F, Liu F, Chen Z, Hua Y, Keep RF, Xi G. Hydrocephalus after intraventricular hemorrhage: the role of thrombin. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 34: 489-94. PMID 24326390 DOI: 10.1038/jcbfm.2013.225  0.312
2013 Xie Q, Xi G, Gong Y, Keep R, Muraszko K, Hua Y. Protease activated receptor-1 and brain edema formation in glioma models. Acta Neurochirurgica. Supplement. 118: 191-4. PMID 23564130 DOI: 10.1007/978-3-7091-1434-6_35  0.384
2013 Okubo S, Xi G, Keep RF, Muraszko KM, Hua Y. Cerebral hemorrhage, brain edema, and heme oxygenase-1 expression after experimental traumatic brain injury. Acta Neurochirurgica. Supplement. 118: 83-7. PMID 23564109 DOI: 10.1007/978-3-7091-1434-6_14  0.317
2013 Kuroiwa T, Xi G, Hua Y, Nagaraja TN, Fenstermacher JD, Keep RF. Brain edema and blood-brain barrier opening after photothrombotic ischemia in rat. Acta Neurochirurgica. Supplement. 118: 11-5. PMID 23564097 DOI: 10.1007/978-3-7091-1434-6_2  0.322
2013 He Y, Liu W, Koch LG, Britton SL, Keep RF, Xi G, Hua Y. Susceptibility to intracerebral hemorrhage-induced brain injury segregates with low aerobic capacity in rats. Neurobiology of Disease. 49: 22-8. PMID 22939993 DOI: 10.1016/j.nbd.2012.08.014  0.332
2012 He Y, Karabiyikoglu M, Hua Y, Keep RF, Xi G. Ischemic preconditioning attenuates brain edema after experimental intracerebral hemorrhage. Translational Stroke Research. 3: 180-7. PMID 23162674 DOI: 10.1007/s12975-012-0171-z  0.359
2011 Chen Z, Xi G, Mao Y, Keep RF, Hua Y. Effects of progesterone and testosterone on ICH-induced brain injury in rats. Acta Neurochirurgica. Supplement. 111: 289-93. PMID 21725770 DOI: 10.1007/978-3-7091-0693-8_48  0.335
2011 Xie Q, Guan J, Wu G, Xi G, Keep RF, Hua Y. Tamoxifen treatment for intracerebral hemorrhage. Acta Neurochirurgica. Supplement. 111: 271-5. PMID 21725767 DOI: 10.1007/978-3-7091-0693-8_45  0.312
2011 Lee JY, Keep RF, Hua Y, Ernestus RI, Xi G. Deferoxamine reduces early brain injury following subarachnoid hemorrhage. Acta Neurochirurgica. Supplement. 112: 101-6. PMID 21691996 DOI: 10.1007/978-3-7091-0661-7_18  0.302
2011 Wu G, Bao X, Xi G, Keep RF, Thompson BG, Hua Y. Brain injury after intracerebral hemorrhage in spontaneously hypertensive rats. Journal of Neurosurgery. 114: 1805-11. PMID 21294617 DOI: 10.3171/2011.1.JNS101530  0.336
2011 Chen Z, Gao C, Hua Y, Keep RF, Muraszko K, Xi G. Role of iron in brain injury after intraventricular hemorrhage. Stroke; a Journal of Cerebral Circulation. 42: 465-70. PMID 21164132 DOI: 10.1161/Strokeaha.110.602755  0.307
2010 Okauchi M, Hua Y, Keep RF, Morgenstern LB, Schallert T, Xi G. Deferoxamine treatment for intracerebral hemorrhage in aged rats: therapeutic time window and optimal duration. Stroke; a Journal of Cerebral Circulation. 41: 375-82. PMID 20044521 DOI: 10.1161/Strokeaha.109.569830  0.327
2010 Nakamura T, Kuroda Y, Hosomi N, Okabe N, Kawai N, Tamiya T, Xi G, Keep RF, Itano T. Serine protease inhibitor attenuates intracerebral hemorrhage-induced brain injury and edema formation in rat Acta Neurochirurgica. Supplement. 106: 307-310. PMID 19812969 DOI: 10.1007/978-3-211-98811-4-57  0.332
2010 Wu J, Yang S, Hua Y, Liu W, Keep RF, Xi G. Minocycline attenuates brain edema, brain atrophy and neurological deficits after intracerebral hemorrhage Acta Neurochirurgica. Supplement. 106: 147-150. PMID 19812938 DOI: 10.1007/978-3-211-98811-4-26  0.338
2009 Xing Y, Hua Y, Keep RF, Xi G. Effects of deferoxamine on brain injury after transient focal cerebral ischemia in rats with hyperglycemia Brain Research. 1291: 113-121. PMID 19631616 DOI: 10.1016/j.brainres.2009.07.032  0.325
2009 Lee JY, He Y, Sagher O, Keep R, Hua Y, Xi G. Activated autophagy pathway in experimental subarachnoid hemorrhage Brain Research. 1287: 126-135. PMID 19538949 DOI: 10.1016/J.Brainres.2009.06.028  0.378
2009 Okauchi M, Hua Y, Keep RF, Morgenstern LB, Xi G. Effects of deferoxamine on intracerebral hemorrhage-induced brain injury in aged rats Stroke. 40: 1858-1863. PMID 19286595 DOI: 10.1161/Strokeaha.108.535765  0.317
2009 Hua Y, Keep RF, Gu Y, Xi G. Thrombin and brain recovery after intracerebral hemorrhage Stroke. 40: S88-S89. PMID 19064789 DOI: 10.1161/STROKEAHA.108.533281  0.3
2009 Kuroiwa T, Xi G, Hua Y, Nagaraja TN, Fenstermacher JD, Keep RF. Development of a rat model of photothrombotic ischemia and infarction within the caudoputamen. Stroke; a Journal of Cerebral Circulation. 40: 248-53. PMID 19038913 DOI: 10.1161/STROKEAHA.108.527853  0.307
2009 Okauchi M, Xi G, Keep RF, Hua Y. Tissue-type transglutaminase and the effects of cystamine on intracerebral hemorrhage-induced brain edema and neurological deficits Brain Research. 1249: 229-236. PMID 19007756 DOI: 10.1016/j.brainres.2008.10.035  0.322
2008 Qin Z, Xi G, Keep RF, Silbergleit R, He Y, Hua Y. Hyperbaric oxygen for experimental intracerebral hemorrhage Acta Neurochirurgica, Supplementum. 113-117. PMID 19066094 DOI: 10.1007/978-3-211-09469-3-23  0.303
2008 Gong Y, Xi G, Hu H, Gu Y, Huang F, Keep RF, Hua Y. Increase in brain thrombin activity after experimental intracerebral hemorrhage Acta Neurochirurgica, Supplementum. 47-50. PMID 19066081 DOI: 10.1007/978-3-211-09469-3-10  0.332
2008 Song S, Hua Y, Keep RF, He Y, Wang J, Wu J, Xi G. Deferoxamine reduces brain swelling in a rat model of hippocampal intracerebral hemorrhage Acta Neurochirurgica, Supplementum. 13-18. PMID 19066074 DOI: 10.1007/978-3-211-09469-3-3  0.311
2008 Yang S, Song S, Hua Y, Nakamura T, Keep RF, Xi G. Effects of thrombin on neurogenesis after intracerebral hemorrhage Stroke. 39: 2079-2084. PMID 18436875 DOI: 10.1161/STROKEAHA.107.508911  0.354
2008 Nakamura T, Kuroda Y, Yamashita S, Zhang X, Miyamoto O, Tamiya T, Nagao S, Xi G, Keep RF, Itano T. Edaravone attenuates brain edema and neurologic deficits in a rat model of acute intracerebral hemorrhage Stroke. 39: 463-469. PMID 18096835 DOI: 10.1161/STROKEAHA.107.486654  0.33
2008 Lee JY, Huang DL, Keep R, Sagher O. Characterization of an improved double hemorrhage rat model for the study of delayed cerebral vasospasm. Journal of Neuroscience Methods. 168: 358-66. PMID 18096241 DOI: 10.1016/J.Jneumeth.2007.10.029  0.367
2007 Cannon JR, Xi G, Keep RF. Recent research on changes in genomic regulation and protein expression in intracerebral haemorrhage. International Journal of Stroke : Official Journal of the International Stroke Society. 2: 265-9. PMID 18705926 DOI: 10.1111/J.1747-4949.2007.00160.X  0.481
2007 Cannon JR, Hua Y, Richardson RJ, Xi G, Keep RF, Schallert T. The effect of thrombin on a 6-hydroxydopamine model of Parkinson's disease depends on timing. Behavioural Brain Research. 183: 161-8. PMID 17629581 DOI: 10.1016/J.Bbr.2007.06.004  0.552
2007 Qin Z, Song S, Xi G, Silbergleit R, Keep RF, Hoff JT, Hua Y. Preconditioning with hyperbaric oxygen attenuates brain edema after experimental intracerebral hemorrhage Neurosurgical Focus. 22: E13. PMID 17613231  0.342
2006 Cannon JR, Keep RF, Schallert T, Hua Y, Richardson RJ, Xi G. Protease-activated receptor-1 mediates protection elicited by thrombin preconditioning in a rat 6-hydroxydopamine model of Parkinson's disease. Brain Research. 1116: 177-86. PMID 16934779 DOI: 10.1016/J.Brainres.2006.07.094  0.508
2006 Gong Y, Tian H, Xi G, Keep RF, Hoff JT, Hua Y. Systemic zinc protoporphyrin administration reduces intracerebral hemorrhage-induced brain injury Acta Neurochirurgica, Supplementum. 232-236. PMID 16671461 DOI: 10.1007/3-211-30714-1_50  0.353
2006 Cannon JR, Nakamura T, Keep RF, Richardson RJ, Hua Y, Xi G. Dopamine changes in a rat model of intracerebral hemorrhage. Acta Neurochirurgica. Supplement. 96: 222-6. PMID 16671459 DOI: 10.1007/3-211-30714-1_48  0.481
2006 Lodhia KR, Shakui P, Keep RF. Hydrocephalus in a rat model of intraventricular hemorrhage Acta Neurochirurgica, Supplementum. 207-211. PMID 16671456 DOI: 10.1007/3-211-30714-1-45  0.3
2006 Gong Y, Xi GH, Keep RF, Hoff JT, Hua Y. Complement inhibition attenuates brain edema and neurological deficits induced by thrombin. Acta Neurochirurgica. Supplement. 95: 389-92. PMID 16463887 DOI: 10.1007/3-211-32318-X_79  0.303
2006 Karabiyikoglu M, Keep R, Hua Y, Xi G. Acute subdural hematoma: new model delineation and effects of coagulation inhibitors. Neurosurgery. 57: 565-72; discussion 5. PMID 16145537 DOI: 10.1227/01.Neu.0000170435.47739.Ae  0.377
2005 Hua Y, Wu J, Pecina S, Yang S, Schallert T, Keep RF, Xi G. Ischemic preconditioning procedure induces behavioral deficits in the absence of brain injury? Neurological Research. 27: 261-7. PMID 15845209 DOI: 10.1179/016164105X25270  0.342
2005 Cannon JR, Keep RF, Hua Y, Richardson RJ, Schallert T, Xi G. Thrombin preconditioning provides protection in a 6-hydroxydopamine Parkinson's disease model. Neuroscience Letters. 373: 189-94. PMID 15619541 DOI: 10.1016/J.Neulet.2004.10.089  0.531
2005 Wan S, Xi G, Keep R, Hoff J, Hua Y. Deferoxamine reduces CSF free iron levels following intracerebral hemorrhage in rats Journal of Cerebral Blood Flow & Metabolism. 25: S43-S43. DOI: 10.1038/Sj.Jcbfm.9591524.0043  0.312
2004 Xi G, Wu J, Jiang Y, Hua Y, Keep RF, Hoff JT. Thrombin preconditioning upregulates transferrin and transferrin receptor and reduces brain edema induced by lysed red blood cells. Acta Neurochirurgica. Supplement. 86: 449-52. PMID 14753484 DOI: 10.1007/978-3-7091-0651-8_92  0.319
2004 Hua Y, Wu J, Keep RF, Hoff JT, Xi G. Thrombin exacerbates brain edema in focal cerebral ischemia. Acta Neurochirurgica. Supplement. 86: 163-6. PMID 14753426 DOI: 10.1007/978-3-7091-0651-8_34  0.314
2004 Karabiyikoglu M, Hua Y, Keep RF, Ennis SR, Xi G. Intracerebral hirudin injection attenuates ischemic damage and neurologic deficits without altering local cerebral blood flow. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 24: 159-66. PMID 14747742 DOI: 10.1097/01.WCB.0000100062.36077.84  0.333
2003 Nakamura T, Keep RF, Hua Y, Schallert T, Hoff JT, Xi G. Deferoxamine-induced attenuation of brain edema and neurological deficits in a rat model of intracerebral hemorrhage. Neurosurgical Focus. 15: ECP4. PMID 15344903 DOI: 10.3171/Foc.2003.15.4.10  0.304
2003 Xi G, Reiser G, Keep RF. The role of thrombin and thrombin receptors in ischemic, hemorrhagic and traumatic brain injury: deleterious or protective? Journal of Neurochemistry. 84: 3-9. PMID 12485396 DOI: 10.1046/j.1471-4159.2003.01268.x  0.311
2003 Masada T, Hua Y, Xi G, Ennis SR, Keep RF. Effect of ischemic preconditioning on edema formation and cerebrovascular injury following focal cerebral ischemia. Acta Neurochirurgica. Supplement. 81: 265-8. PMID 12168321 DOI: 10.1007/978-3-7091-6738-0_68  0.358
2002 Xi G, Keep RF, Hoff JT. Pathophysiology of brain edema formation. Neurosurgery Clinics of North America. 13: 371-83. PMID 12486926 DOI: 10.1016/S1042-3680(02)00007-4  0.308
2002 Wu J, Hua Y, Keep RF, Schallert T, Hoff JT, Xi G. Oxidative brain injury from extravasated erythrocytes after intracerebral hemorrhage. Brain Research. 953: 45-52. PMID 12384237 DOI: 10.1016/S0006-8993(02)03268-7  0.322
2001 Xi G, Hua Y, Keep RF, Hoff JT. Induction of colligin may attenuate brain edema following intracerebral hemorrhage. Acta Neurochirurgica. Supplement. 76: 501-5. PMID 11450078 DOI: 10.1007/978-3-7091-6346-7_105  0.325
2001 Sagher O, Huang D, Keep R. 811 Spinal Cord Stimulation Increases Cerebral Blood Flow and Reduces Stroke Volume in a Focal Cerebral Ischemia Model Neurosurgery. 49: 539-539. DOI: 10.1097/00006123-200108000-00175  0.313
2000 Gong C, Hoff JT, Keep RF. Acute inflammatory reaction following experimental intracerebral hemorrhage in rat. Brain Research. 871: 57-65. PMID 10882783 DOI: 10.1016/S0006-8993(00)02427-6  0.313
2000 Masada T, Xi G, Hua Y, Keep RF. The effects of thrombin preconditioning on focal cerebral ischemia in rats. Brain Research. 867: 173-9. PMID 10837811 DOI: 10.1016/S0006-8993(00)02302-7  0.359
1998 Xi G, Keep RF, Hoff JT. Erythrocytes and delayed brain edema formation following intracerebral hemorrhage in rats. Journal of Neurosurgery. 89: 991-6. PMID 9833826 DOI: 10.3171/JNS.1998.89.6.0991  0.309
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