| Year |
Citation |
Score |
| 2020 |
Shao H, Zhu Q, Lu H, Chang A, Gao C, Zhou Q, Luo K. HEXIM1 controls P-TEFb processing and regulates drug sensitivity in triple negative breast cancer. Molecular Biology of the Cell. mbcE19120704. PMID 32520633 DOI: 10.1091/Mbc.E19-12-0704 |
0.359 |
|
| 2020 |
Wu J, Xue Y, Gao X, Zhou Q. Host cell factors stimulate HIV-1 transcription by antagonizing substrate-binding function of Siah1 ubiquitin ligase to stabilize transcription elongation factor ELL2. Nucleic Acids Research. PMID 32479599 DOI: 10.1093/Nar/Gkaa461 |
0.404 |
|
| 2020 |
Lu Y, Wu T, Gutman O, Lu H, Zhou Q, Henis YI, Luo K. Phase separation of TAZ compartmentalizes the transcription machinery to promote gene expression. Nature Cell Biology. PMID 32203417 DOI: 10.1038/S41556-020-0485-0 |
0.332 |
|
| 2019 |
Yu D, Cattoglio C, Xue Y, Zhou Q. A complex between DYRK1A and DCAF7 phosphorylates the C-terminal domain of RNA polymerase II to promote myogenesis. Nucleic Acids Research. PMID 30864669 DOI: 10.1093/Nar/Gkz162 |
0.373 |
|
| 2019 |
Li Z, Wu J, Chavez L, Hoh R, Deeks SG, Pillai SK, Zhou Q. Reiterative Enrichment and Authentication of CRISPRi Targets (REACT) identifies the proteasome as a key contributor to HIV-1 latency. Plos Pathogens. 15: e1007498. PMID 30645648 DOI: 10.1371/Journal.Ppat.1007498 |
0.358 |
|
| 2018 |
Yu D, Liu R, Yang G, Zhou Q. The PARP1-Siah1 Axis Controls HIV-1 Transcription and Expression of Siah1 Substrates. Cell Reports. 23: 3741-3749. PMID 29949759 DOI: 10.1016/J.Celrep.2018.05.084 |
0.388 |
|
| 2018 |
Lu H, Yu D, Hansen AS, Ganguly S, Liu R, Heckert A, Darzacq X, Zhou Q. Phase-separation mechanism for C-terminal hyperphosphorylation of RNA polymerase II. Nature. PMID 29849146 DOI: 10.1038/S41586-018-0174-3 |
0.353 |
|
| 2018 |
Li Z, Mbonye U, Feng Z, Wang X, Gao X, Karn J, Zhou Q. The KAT5-Acetyl-Histone4-Brd4 axis silences HIV-1 transcription and promotes viral latency. Plos Pathogens. 14: e1007012. PMID 29684085 DOI: 10.1371/Journal.Ppat.1007012 |
0.381 |
|
| 2017 |
Wu J, Ao MT, Shao R, Wang HR, Yu D, Fang MJ, Gao X, Wu Z, Zhou Q, Xue YH. A chalcone derivative reactivates latent HIV-1 transcription through activating P-TEFb and promoting Tat-SEC interaction on viral promoter. Scientific Reports. 7: 10657. PMID 28878233 DOI: 10.1038/S41598-017-10728-W |
0.403 |
|
| 2016 |
Zhao Y, Karijolich J, Glaunsinger B, Zhou Q. Pseudouridylation of 7SK snRNA promotes 7SK snRNP formation to suppress HIV-1 transcription and escape from latency. Embo Reports. PMID 27558685 DOI: 10.15252/Embr.201642682 |
0.313 |
|
| 2016 |
Schulze-Gahmen U, Echeverria I, Stjepanovic G, Bai Y, Lu H, Schneidman-Duhovny D, Doudna JA, Zhou Q, Sali A, Hurley JH. Author response: Insights into HIV-1 proviral transcription from integrative structure and dynamics of the Tat:AFF4:P-TEFb:TAR complex Elife. DOI: 10.7554/Elife.15910.025 |
0.363 |
|
| 2014 |
Lu H, Li Z, Xue Y, Schulze-Gahmen U, Johnson JR, Krogan NJ, Alber T, Zhou Q. AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation. Proceedings of the National Academy of Sciences of the United States of America. 111: E15-24. PMID 24367103 DOI: 10.1073/Pnas.1318503111 |
0.313 |
|
| 2014 |
Schulze-Gahmen U, Lu H, Zhou Q, Alber T. Author response: AFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoter Elife. DOI: 10.7554/Elife.02375.015 |
0.361 |
|
| 2013 |
Chou S, Upton H, Bao K, Schulze-Gahmen U, Samelson AJ, He N, Nowak A, Lu H, Krogan NJ, Zhou Q, Alber T. HIV-1 Tat recruits transcription elongation factors dispersed along a flexible AFF4 scaffold. Proceedings of the National Academy of Sciences of the United States of America. 110: E123-31. PMID 23251033 DOI: 10.1073/Pnas.1216971110 |
0.397 |
|
| 2013 |
Li Z, Guo J, Wu Y, Zhou Q. The BET bromodomain inhibitor JQ1 activates HIV latency through antagonizing Brd4 inhibition of Tat-transactivation. Nucleic Acids Research. 41: 277-87. PMID 23087374 DOI: 10.1093/Nar/Gks976 |
0.38 |
|
| 2013 |
Schulze-Gahmen U, Upton H, Birnberg A, Bao K, Chou S, Krogan NJ, Zhou Q, Alber T. Author response: The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat Elife. DOI: 10.7554/Elife.00327.020 |
0.337 |
|
| 2012 |
Liu M, Hsu J, Chan C, Li Z, Zhou Q. The ubiquitin ligase Siah1 controls ELL2 stability and formation of super elongation complexes to modulate gene transcription. Molecular Cell. 46: 325-34. PMID 22483617 DOI: 10.1016/J.Molcel.2012.03.007 |
0.397 |
|
| 2012 |
Zhou Q, Li T, Price DH. RNA polymerase II elongation control. Annual Review of Biochemistry. 81: 119-43. PMID 22404626 DOI: 10.1146/Annurev-Biochem-052610-095910 |
0.337 |
|
| 2011 |
Ott M, Geyer M, Zhou Q. The control of HIV transcription: keeping RNA polymerase II on track. Cell Host & Microbe. 10: 426-35. PMID 22100159 DOI: 10.1016/J.Chom.2011.11.002 |
0.404 |
|
| 2011 |
He N, Chan CK, Sobhian B, Chou S, Xue Y, Liu M, Alber T, Benkirane M, Zhou Q. Human Polymerase-Associated Factor complex (PAFc) connects the Super Elongation Complex (SEC) to RNA polymerase II on chromatin. Proceedings of the National Academy of Sciences of the United States of America. 108: E636-45. PMID 21873227 DOI: 10.1073/Pnas.1107107108 |
0.375 |
|
| 2011 |
He N, Zhou Q. New insights into the control of HIV-1 transcription: when Tat meets the 7SK snRNP and super elongation complex (SEC). Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 6: 260-8. PMID 21360054 DOI: 10.1007/s11481-011-9267-6 |
0.326 |
|
| 2010 |
He N, Liu M, Hsu J, Xue Y, Chou S, Burlingame A, Krogan NJ, Alber T, Zhou Q. HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription. Molecular Cell. 38: 428-38. PMID 20471948 DOI: 10.1016/J.Molcel.2010.04.013 |
0.422 |
|
| 2010 |
Chen R, Liu M, Zhang K, Zhou Q. Isolation and functional characterization of P-TEFb-associated factors that control general and HIV-1 transcriptional elongation. Methods (San Diego, Calif.). 53: 85-90. PMID 20385240 DOI: 10.1016/J.Ymeth.2010.04.005 |
0.433 |
|
| 2010 |
Xue Y, Yang Z, Chen R, Zhou Q. A capping-independent function of MePCE in stabilizing 7SK snRNA and facilitating the assembly of 7SK snRNP. Nucleic Acids Research. 38: 360-9. PMID 19906723 DOI: 10.1093/Nar/Gkp977 |
0.383 |
|
| 2008 |
Chen R, Liu M, Li H, Xue Y, Ramey WN, He N, Ai N, Luo H, Zhu Y, Zhou N, Zhou Q. PP2B and PP1alpha cooperatively disrupt 7SK snRNP to release P-TEFb for transcription in response to Ca2+ signaling. Genes & Development. 22: 1356-68. PMID 18483222 DOI: 10.1101/Gad.1636008 |
0.357 |
|
| 2008 |
He N, Jahchan NS, Hong E, Li Q, Bayfield MA, Maraia RJ, Luo K, Zhou Q. A La-related protein modulates 7SK snRNP integrity to suppress P-TEFb-dependent transcriptional elongation and tumorigenesis. Molecular Cell. 29: 588-99. PMID 18249148 DOI: 10.1016/J.Molcel.2008.01.003 |
0.375 |
|
| 2008 |
Yang Z, He N, Zhou Q. Brd4 recruits P-TEFb to chromosomes at late mitosis to promote G1 gene expression and cell cycle progression. Molecular and Cellular Biology. 28: 967-76. PMID 18039861 DOI: 10.1128/Mcb.01020-07 |
0.378 |
|
| 2007 |
Barboric M, Yik JH, Czudnochowski N, Yang Z, Chen R, Contreras X, Geyer M, Matija Peterlin B, Zhou Q. Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription. Nucleic Acids Research. 35: 2003-12. PMID 17341462 DOI: 10.1093/Nar/Gkm063 |
0.428 |
|
| 2006 |
He N, Pezda AC, Zhou Q. Modulation of a P-TEFb functional equilibrium for the global control of cell growth and differentiation. Molecular and Cellular Biology. 26: 7068-76. PMID 16980611 DOI: 10.1128/Mcb.00778-06 |
0.376 |
|
| 2006 |
Zhou Q, Yik JH. The Yin and Yang of P-TEFb regulation: implications for human immunodeficiency virus gene expression and global control of cell growth and differentiation. Microbiology and Molecular Biology Reviews : Mmbr. 70: 646-59. PMID 16959964 DOI: 10.1128/Mmbr.00011-06 |
0.43 |
|
| 2005 |
Yang Z, Yik JH, Chen R, He N, Jang MK, Ozato K, Zhou Q. Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4. Molecular Cell. 19: 535-45. PMID 16109377 DOI: 10.1016/J.Molcel.2005.06.029 |
0.424 |
|
| 2005 |
Yik JH, Chen R, Pezda AC, Zhou Q. Compensatory contributions of HEXIM1 and HEXIM2 in maintaining the balance of active and inactive positive transcription elongation factor b complexes for control of transcription. The Journal of Biological Chemistry. 280: 16368-76. PMID 15713661 DOI: 10.1074/Jbc.M500912200 |
0.416 |
|
| 2004 |
Yik JH, Chen R, Pezda AC, Samford CS, Zhou Q. A human immunodeficiency virus type 1 Tat-like arginine-rich RNA-binding domain is essential for HEXIM1 to inhibit RNA polymerase II transcription through 7SK snRNA-mediated inactivation of P-TEFb. Molecular and Cellular Biology. 24: 5094-105. PMID 15169877 DOI: 10.1128/Mcb.24.12.5094-5105.2004 |
0.401 |
|
| 2004 |
Chen R, Yang Z, Zhou Q. Phosphorylated positive transcription elongation factor b (P-TEFb) is tagged for inhibition through association with 7SK snRNA. The Journal of Biological Chemistry. 279: 4153-60. PMID 14627702 DOI: 10.1074/Jbc.M310044200 |
0.381 |
|
| 2003 |
Yik JH, Chen R, Nishimura R, Jennings JL, Link AJ, Zhou Q. Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA. Molecular Cell. 12: 971-82. PMID 14580347 DOI: 10.1016/S1097-2765(03)00388-5 |
0.407 |
|
| 2002 |
Chen D, Wang M, Zhou S, Zhou Q. HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim. The Embo Journal. 21: 6801-10. PMID 12486001 DOI: 10.1093/Emboj/Cdf683 |
0.326 |
|
| 2001 |
Fong YW, Zhou Q. Stimulatory effect of splicing factors on transcriptional elongation. Nature. 414: 929-33. PMID 11780068 DOI: 10.1038/414929A |
0.382 |
|
| 2001 |
Yang Z, Zhu Q, Luo K, Zhou Q. The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription Nature. 414: 317-322. PMID 11713532 DOI: 10.1038/35104575 |
0.44 |
|
| 2000 |
Fong YW, Zhou Q. Relief of two built-In autoinhibitory mechanisms in P-TEFb is required for assembly of a multicomponent transcription elongation complex at the human immunodeficiency virus type 1 promoter. Molecular and Cellular Biology. 20: 5897-907. PMID 10913173 DOI: 10.1128/Mcb.20.16.5897-5907.2000 |
0.426 |
|
| 2000 |
O'Keeffe B, Fong Y, Chen D, Zhou S, Zhou Q. Requirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated Tat stimulation of HIV-1 transcription Journal of Biological Chemistry. 275: 279-287. PMID 10617616 DOI: 10.1074/Jbc.275.1.279 |
0.4 |
|
| 1999 |
Luo K, Stroschein SL, Wang W, Chen D, Martens E, Zhou S, Zhou Q. The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling. Genes & Development. 13: 2196-206. PMID 10485843 DOI: 10.1101/Gad.13.17.2196 |
0.341 |
|
| 1999 |
Chen D, Zhou Q. Tat activates human immunodeficiency virus type 1 transcriptional elongation independent of TFIIH kinase. Molecular and Cellular Biology. 19: 2863-71. PMID 10082552 DOI: 10.1128/Mcb.19.4.2863 |
0.422 |
|
| 1999 |
Chen D, Fong Y, Zhou Q. Specific interaction of Tat with the human but not rodent P-TEFb complex mediates the species-specific Tat activation of HIV-1 transcription Proceedings of the National Academy of Sciences of the United States of America. 96: 2728-2733. PMID 10077579 DOI: 10.1073/Pnas.96.6.2728 |
0.408 |
|
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