| Year |
Citation |
Score |
| 2020 |
Qi L, Zang H, Wu W, Nagarkatti P, Nagarkatti M, Liu Q, Robbins J, Wang X, Cui T. CYLD exaggerates pressure overload-induced cardiomyopathy via suppressing autolysosome efflux in cardiomyocytes. Journal of Molecular and Cellular Cardiology. PMID 32553594 DOI: 10.1016/J.Yjmcc.2020.06.004 |
0.448 |
|
| 2020 |
Xu N, Gulick J, Osinska H, Yu Y, McLendon PM, Shay-Winkler K, Robbins J, Yutzey KE. Ube2v1 Positively Regulates Protein Aggregation by Modulating Ubiquitin Proteasome System Performance Partially through K63 Ubiquitination. Circulation Research. PMID 32081062 DOI: 10.1161/Circresaha.119.316444 |
0.419 |
|
| 2019 |
Zheng D, Su Z, Zhang Y, Ni R, Fan GC, Robbins J, Song LS, Li J, Peng T. Calpain-2 promotes MKP-1 expression protecting cardiomyocytes in both in vitro and in vivo mouse models of doxorubicin-induced cardiotoxicity. Archives of Toxicology. PMID 30810770 DOI: 10.1007/s00204-019-02405-w |
0.432 |
|
| 2019 |
Rahmanseresht S, Lee K, Robbins J, Warshaw DM, Craig R, Previs MJ. Resolving the Actin Lattice and Identifying the Relative Position of MYBP-C's N-Terminus in Cardiac Muscle using Storm Microscopy Biophysical Journal. 116: 116a. DOI: 10.1016/J.Bpj.2018.11.653 |
0.352 |
|
| 2018 |
Meng Q, Bhandary B, Bhuiyan MS, James J, Osinska H, Valiente-Alandi I, Shay-Winkler K, Gulick J, Molkentin JD, Blaxall BC, Robbins J. Myofibroblast-Specific TGFβ Receptor II Signaling in the Fibrotic Response to Cardiac Myosin Binding Protein C-Induced Cardiomyopathy. Circulation Research. 123: 1285-1297. PMID 30566042 DOI: 10.1161/Circresaha.118.313089 |
0.449 |
|
| 2018 |
Abdullah CS, Alam S, Aishwarya R, Miriyala S, Panchatcharam M, Bhuiyan MAN, Peretik JM, Orr AW, James J, Osinska H, Robbins J, Lorenz JN, Bhuiyan MS. Cardiac Dysfunction in the Sigma 1 Receptor Knockout Mouse Associated With Impaired Mitochondrial Dynamics and Bioenergetics. Journal of the American Heart Association. 7: e009775. PMID 30371279 DOI: 10.1161/Jaha.118.009775 |
0.443 |
|
| 2018 |
Bhandary B, Meng Q, James J, Osinska H, Gulick J, Valiente-Alandi I, Sargent MA, Bhuiyan MS, Blaxall BC, Molkentin JD, Robbins J. Cardiac Fibrosis in Proteotoxic Cardiac Disease is Dependent Upon Myofibroblast TGF -β Signaling. Journal of the American Heart Association. 7: e010013. PMID 30371263 DOI: 10.1161/Jaha.118.010013 |
0.404 |
|
| 2018 |
Lowey S, Bretton V, Joel PB, Trybus KM, Gulick J, Robbins J, Kalganov A, Cornachione AS, Rassier DE. Hypertrophic cardiomyopathy R403Q mutation in rabbit β-myosin reduces contractile function at the molecular and myofibrillar levels. Proceedings of the National Academy of Sciences of the United States of America. PMID 30322937 DOI: 10.1073/pnas.1802967115 |
0.366 |
|
| 2018 |
Baker RS, Zafar F, Kimura N, Knilans T, Osinska H, Robbins J, Taylor M, Morales DLS. In Vivo Remodeling of an Extracellular Matrix Cardiac Patch in an Ovine Model. Asaio Journal (American Society For Artificial Internal Organs : 1992). PMID 30153196 DOI: 10.1097/MAT.0000000000000864 |
0.326 |
|
| 2018 |
Alam S, Abdullah CS, Aishwarya R, Miriyala S, Panchatcharam M, Peretik JM, Orr AW, James J, Robbins J, Bhuiyan MS. Aberrant Mitochondrial Fission Is Maladaptive in Desmin Mutation-Induced Cardiac Proteotoxicity. Journal of the American Heart Association. 7. PMID 29987122 DOI: 10.1161/Jaha.118.009289 |
0.43 |
|
| 2018 |
Singh SR, Robbins J. Desmin and Cardiac Disease: An Unfolding Story. Circulation Research. 122: 1324-1326. PMID 29748359 DOI: 10.1161/CIRCRESAHA.118.312965 |
0.362 |
|
| 2018 |
Alam S, Abdullah CS, Aishwarya R, Miriyala S, Panchatcharam M, Green JP, Orr AW, James J, Robbins J, Bhuiyan MS. Abstract 408: Defective Mitochondrial Dynamics Contribute to Cardiac Contractile Dysfunction in Desminopathy Circulation Research. 123. DOI: 10.1161/res.123.suppl_1.408 |
0.342 |
|
| 2018 |
Abdullah CS, Alam S, Aishwarya R, Miriyala S, Panchatcharam M, Orr AW, James J, Robbins J, Lorenz JN, Bhuiyan MS. Abstract 406: Loss of Sigmar1 Leads to Impaired Mitochondrial Respiration, Altered Mitochondrial Dynamics and Development of Cardiac Contractile Dysfunction Circulation Research. 123. DOI: 10.1161/res.123.suppl_1.406 |
0.314 |
|
| 2018 |
Meng Q, Bhandary B, Osinska H, James J, Shay-Winkler K, Gulick J, McNamara J, Bhuiyan MS, Sadayappan S, Robbins J. Abstract 265: TGF Beta Signaling and Fibrosis in cMyBP-C-dependent Cardiac Disease Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.265 |
0.319 |
|
| 2017 |
Singh SR, Zech ATL, Geertz B, Reischmann-Düsener S, Osinska H, Prondzynski M, Krämer E, Meng Q, Redwood C, van der Velden J, Robbins J, Schlossarek S, Carrier L. Activation of Autophagy Ameliorates Cardiomyopathy in Mybpc3-Targeted Knockin Mice. Circulation. Heart Failure. 10. PMID 29021349 DOI: 10.1161/CIRCHEARTFAILURE.117.004140 |
0.383 |
|
| 2017 |
Meng Q, Bhandary B, Osinska H, James J, Xu N, Shay-Winkler K, Gulick J, Willis MS, Lander C, Robbins J. MMI-0100 Inhibits Cardiac Fibrosis in a Mouse Model Overexpressing Cardiac Myosin Binding Protein C. Journal of the American Heart Association. 6. PMID 28871043 DOI: 10.1161/Jaha.117.006590 |
0.426 |
|
| 2017 |
Xu N, Bitan G, Schrader T, Klärner FG, Osinska H, Robbins J. Inhibition of Mutant αB Crystallin-Induced Protein Aggregation by a Molecular Tweezer. Journal of the American Heart Association. 6. PMID 28862927 DOI: 10.1161/Jaha.117.006182 |
0.39 |
|
| 2017 |
McLendon PM, Davis G, Gulick J, Singh SR, Xu N, Salomonis N, Molkentin JD, Robbins J. An Unbiased High Throughput Screen to Identify Novel Effectors that Impact on Cardiomyocyte Aggregate Levels. Circulation Research. PMID 28655832 DOI: 10.1161/Circresaha.117.310945 |
0.339 |
|
| 2016 |
Gupta MK, Robbins J. Making the Connections: Autophagy and Post-translational Modifications in Cardiomyocytes. Autophagy. 0. PMID 27573291 DOI: 10.1080/15548627.2016.1215384 |
0.455 |
|
| 2016 |
Bhuiyan MS, McLendon P, James J, Osinska H, Gulick J, Bhandary B, Lorenz JN, Robbins J. In vivo definition of cardiac myosin-binding protein C's critical interactions with myosin. Pflugers Archiv : European Journal of Physiology. PMID 27568194 DOI: 10.1007/s00424-016-1873-y |
0.394 |
|
| 2016 |
Topkara VK, Chambers KT, Yang KC, Tzeng HP, Evans S, Weinheimer C, Kovacs A, Robbins J, Barger P, Mann DL. Functional significance of the discordance between transcriptional profile and left ventricular structure/function during reverse remodeling. Jci Insight. 1: e86038. PMID 27158672 DOI: 10.1172/Jci.Insight.86038 |
0.413 |
|
| 2016 |
Gupta MK, McLendon PM, Gulick J, James J, Khalili K, Robbins J. UBC9-Mediated Sumoylation Favorably Impacts Cardiac Function in Compromised Hearts. Circulation Research. PMID 27142163 DOI: 10.1161/Circresaha.115.308268 |
0.446 |
|
| 2016 |
Taylor EN, Hoffman MP, Barefield DY, Aninwene GE, Abrishamchi AD, Lynch TL, Govindan S, Osinska H, Robbins J, Sadayappan S, Gilbert RJ. Alterations in Multi-Scale Cardiac Architecture in Association With Phosphorylation of Myosin Binding Protein-C. Journal of the American Heart Association. 5. PMID 27068630 DOI: 10.1161/JAHA.115.002836 |
0.417 |
|
| 2016 |
Travers JG, Kamal FA, Robbins J, Yutzey KE, Blaxall BC. Cardiac Fibrosis: The Fibroblast Awakens. Circulation Research. 118: 1021-40. PMID 26987915 DOI: 10.1161/Circresaha.115.306565 |
0.426 |
|
| 2016 |
James J, Robbins J. Healing a Heart Through Genetic Intervention. Circulation Research. 118: 920-2. PMID 26987913 DOI: 10.1161/CIRCRESAHA.116.308468 |
0.357 |
|
| 2016 |
Previs MJ, Mun JY, Michalek AJ, Previs SB, Gulick J, Robbins J, Warshaw DM, Craig R. Phosphorylation and calcium antagonistically tune myosin-binding protein C's structure and function. Proceedings of the National Academy of Sciences of the United States of America. PMID 26908872 DOI: 10.1073/Pnas.1522236113 |
0.326 |
|
| 2015 |
James J, Robbins J. Bringing It All Together: Bedside to Bench and Back Again. Circulation Research. 117: 987-9. PMID 26635381 DOI: 10.1161/CIRCRESAHA.115.307874 |
0.353 |
|
| 2015 |
Bhandary B, Robbins J. Giving credence to controls: Avoiding the false phenotype. Journal of Molecular and Cellular Cardiology. 86: 136-7. PMID 26235056 DOI: 10.1016/j.yjmcc.2015.07.007 |
0.442 |
|
| 2015 |
McLendon PM, Robbins J. Proteotoxicity and cardiac dysfunction. Circulation Research. 116: 1863-82. PMID 25999425 DOI: 10.1161/CIRCRESAHA.116.305372 |
0.376 |
|
| 2015 |
Previs MJ, Prosser BL, Mun JY, Previs SB, Gulick J, Lee K, Robbins J, Craig R, Lederer WJ, Warshaw DM. Myosin-binding protein C corrects an intrinsic inhomogeneity in cardiac excitation-contraction coupling. Science Advances. 1. PMID 25839057 DOI: 10.1126/Sciadv.1400205 |
0.387 |
|
| 2015 |
Duncker DJ, Bakkers J, Brundel BJ, Robbins J, Tardiff JC, Carrier L. Animal and in silico models for the study of sarcomeric cardiomyopathies. Cardiovascular Research. 105: 439-48. PMID 25600962 DOI: 10.1093/Cvr/Cvv006 |
0.318 |
|
| 2015 |
Previs MJ, Prosser BL, Mun JY, Beck Previs S, Gulick J, Lee K, Robbins J, Craig R, Lederer WJ, Warshaw DM. Myosin-Binding Protein C Corrects an Intrinsic Non-Uniformity in Cardiac Excitation-Contraction Coupling Biophysical Journal. 108: 362a. DOI: 10.1016/J.Bpj.2014.11.1984 |
0.348 |
|
| 2014 |
Huby AC, Mendsaikhan U, Takagi K, Martherus R, Wansapura J, Gong N, Osinska H, James JF, Kramer K, Saito K, Robbins J, Khuchua Z, Towbin JA, Purevjav E. Disturbance in Z-disk mechanosensitive proteins induced by a persistent mutant myopalladin causes familial restrictive cardiomyopathy. Journal of the American College of Cardiology. 64: 2765-76. PMID 25541130 DOI: 10.1016/J.Jacc.2014.09.071 |
0.468 |
|
| 2014 |
McLendon PM, Ferguson BS, Osinska H, Bhuiyan MS, James J, McKinsey TA, Robbins J. Tubulin hyperacetylation is adaptive in cardiac proteotoxicity by promoting autophagy. Proceedings of the National Academy of Sciences of the United States of America. 111: E5178-86. PMID 25404307 DOI: 10.1073/pnas.1415589111 |
0.443 |
|
| 2014 |
Gupta MK, Gulick J, Liu R, Wang X, Molkentin JD, Robbins J. Sumo E2 enzyme UBC9 is required for efficient protein quality control in cardiomyocytes. Circulation Research. 115: 721-9. PMID 25097219 DOI: 10.1161/Circresaha.115.304760 |
0.376 |
|
| 2014 |
Dhandapany PS, Razzaque MA, Muthusami U, Kunnoth S, Edwards JJ, Mulero-Navarro S, Riess I, Pardo S, Sheng J, Rani DS, Rani B, Govindaraj P, Flex E, Yokota T, Furutani M, ... ... Robbins J, et al. RAF1 mutations in childhood-onset dilated cardiomyopathy. Nature Genetics. 46: 635-9. PMID 24777450 DOI: 10.1038/Ng.2963 |
0.341 |
|
| 2014 |
Ehrman LA, Nardini D, Ehrman S, Rizvi TA, Gulick J, Krenz M, Dasgupta B, Robbins J, Ratner N, Nakafuku M, Waclaw RR. The protein tyrosine phosphatase Shp2 is required for the generation of oligodendrocyte progenitor cells and myelination in the mouse telencephalon. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 3767-78. PMID 24599474 DOI: 10.1523/Jneurosci.3515-13.2014 |
0.304 |
|
| 2014 |
Alves ML, Dias FA, Gaffin RD, Simon JN, Montminy EM, Biesiadecki BJ, Hinken AC, Warren CM, Utter MS, Davis RT, Sadayappan S, Robbins J, Wieczorek DF, Solaro RJ, Wolska BM. Desensitization of myofilaments to Ca2+ as a therapeutic target for hypertrophic cardiomyopathy with mutations in thin filament proteins. Circulation. Cardiovascular Genetics. 7: 132-43. PMID 24585742 DOI: 10.1161/Circgenetics.113.000324 |
0.377 |
|
| 2014 |
Mun JY, Previs MJ, Yu HY, Gulick J, Tobacman LS, Beck Previs S, Robbins J, Warshaw DM, Craig R. Myosin-binding protein C displaces tropomyosin to activate cardiac thin filaments and governs their speed by an independent mechanism. Proceedings of the National Academy of Sciences of the United States of America. 111: 2170-5. PMID 24477690 DOI: 10.1073/Pnas.1316001111 |
0.348 |
|
| 2014 |
Sandri M, Robbins J. Proteotoxicity: an underappreciated pathology in cardiac disease. Journal of Molecular and Cellular Cardiology. 71: 3-10. PMID 24380730 DOI: 10.1016/j.yjmcc.2013.12.015 |
0.421 |
|
| 2014 |
Wang X, Robbins J. Proteasomal and lysosomal protein degradation and heart disease. Journal of Molecular and Cellular Cardiology. 71: 16-24. PMID 24239609 DOI: 10.1016/j.yjmcc.2013.11.006 |
0.422 |
|
| 2014 |
Gupta MK, Robbins J. Post-translational control of cardiac hemodynamics through myosin binding protein C. Pflã¼Gers Archiv : European Journal of Physiology. 466: 231-6. PMID 24145982 DOI: 10.1007/s00424-013-1377-y |
0.428 |
|
| 2014 |
Liu Y, Lu X, Xiang FL, Poelmann RE, Gittenberger-de Groot AC, Robbins J, Feng Q. Nitric oxide synthase-3 deficiency results in hypoplastic coronary arteries and postnatal myocardial infarction. European Heart Journal. 35: 920-31. PMID 23048191 DOI: 10.1093/eurheartj/ehs306 |
0.312 |
|
| 2014 |
Mun JY, Gulick J, Robbins J, Craig R. Phosphorylation-Induced Structural Change in CMYBP-C affects its Thin Filament Binding and Modulation of Tropomyosin Position Biophysical Journal. 106: 159a. DOI: 10.1016/J.Bpj.2013.11.909 |
0.301 |
|
| 2013 |
Bhuiyan MS, Pattison JS, Osinska H, James J, Gulick J, McLendon PM, Hill JA, Sadoshima J, Robbins J. Enhanced autophagy ameliorates cardiac proteinopathy. The Journal of Clinical Investigation. 123: 5284-97. PMID 24177425 DOI: 10.1172/JCI70877 |
0.422 |
|
| 2013 |
Gupta MK, Gulick J, James J, Osinska H, Lorenz JN, Robbins J. Functional dissection of myosin binding protein C phosphorylation. Journal of Molecular and Cellular Cardiology. 64: 39-50. PMID 24001940 DOI: 10.1016/j.yjmcc.2013.08.006 |
0.437 |
|
| 2013 |
Su H, Li J, Osinska H, Li F, Robbins J, Liu J, Wei N, Wang X. The COP9 signalosome is required for autophagy, proteasome-mediated proteolysis, and cardiomyocyte survival in adult mice. Circulation. Heart Failure. 6: 1049-57. PMID 23873473 DOI: 10.1161/CIRCHEARTFAILURE.113.000338 |
0.381 |
|
| 2013 |
Razzaque MA, Gupta M, Osinska H, Gulick J, Blaxall BC, Robbins J. An endogenously produced fragment of cardiac myosin-binding protein C is pathogenic and can lead to heart failure. Circulation Research. 113: 553-61. PMID 23852539 DOI: 10.1161/CIRCRESAHA.113.301225 |
0.502 |
|
| 2013 |
James J, Robbins J. Ablating a cardiac protein: causality at last. Circulation Research. 112: 1415-9. PMID 23704216 DOI: 10.1161/CIRCRESAHA.113.301425 |
0.415 |
|
| 2013 |
Xu X, Kobayashi S, Chen K, Timm D, Volden P, Huang Y, Gulick J, Yue Z, Robbins J, Epstein PN, Liang Q. Diminished autophagy limits cardiac injury in mouse models of type 1 diabetes. The Journal of Biological Chemistry. 288: 18077-92. PMID 23658055 DOI: 10.1074/Jbc.M113.474650 |
0.358 |
|
| 2013 |
Maiellaro-Rafferty K, Wansapura JP, Mendsaikhan U, Osinska H, James JF, Taylor MD, Robbins J, Kranias EG, Towbin JA, Purevjav E. Altered regional cardiac wall mechanics are associated with differential cardiomyocyte calcium handling due to nebulette mutations in preclinical inherited dilated cardiomyopathy. Journal of Molecular and Cellular Cardiology. 60: 151-60. PMID 23632046 DOI: 10.1016/J.Yjmcc.2013.04.021 |
0.418 |
|
| 2013 |
Lowey S, Bretton V, Gulick J, Robbins J, Trybus KM. Transgenic mouse α- and β-cardiac myosins containing the R403Q mutation show isoform-dependent transient kinetic differences. The Journal of Biological Chemistry. 288: 14780-7. PMID 23580644 DOI: 10.1074/jbc.M113.450668 |
0.378 |
|
| 2013 |
Michalek AJ, Howarth JW, Gulick J, Previs MJ, Robbins J, Rosevear PR, Warshaw DM. Phosphorylation modulates the mechanical stability of the cardiac myosin-binding protein C motif. Biophysical Journal. 104: 442-52. PMID 23442866 DOI: 10.1016/J.Bpj.2012.12.021 |
0.343 |
|
| 2013 |
Wang Y, Tanner BC, Lombardo AT, Tremble SM, Maughan DW, Vanburen P, Lewinter MM, Robbins J, Palmer BM. Cardiac myosin isoforms exhibit differential rates of MgADP release and MgATP binding detected by myocardial viscoelasticity. Journal of Molecular and Cellular Cardiology. 54: 1-8. PMID 23123290 DOI: 10.1016/j.yjmcc.2012.10.010 |
0.304 |
|
| 2013 |
Tanner BC, Wang Y, Robbins J, Palmer BM. Phosphorylation of Serine 282 in Cardiac Myosin Binding Protein-C Increases Myosin MgADP Release and MgATP Binding Rates in Mouse Myocardium Biophysical Journal. 104: 158a. DOI: 10.1016/j.bpj.2012.11.892 |
0.33 |
|
| 2013 |
Young Mun J, Gulick J, Robbins J, Craig R. Electron Microscopy and 3D Reconstruction of Regulated Thin Filaments Decorated with Cardiac Myosin Binding Protein C Biophysical Journal. 104: 312a-313a. DOI: 10.1016/J.Bpj.2012.11.1734 |
0.333 |
|
| 2013 |
Tanner BC, Wang Y, Robbins J, Palmer B. Cardiac Myosin Binding Protein-C Influences the Rates of MgADP Release and MgATP Binding Differently for the Two Cardiac Myosin Isoforms Expressed in Mouse Myocardium Biophysical Journal. 104: 186a. DOI: 10.1016/J.Bpj.2012.11.1052 |
0.344 |
|
| 2013 |
Previs MJ, Yu H, Previs SB, Gulick J, Robbins J, Warshaw DM. Dephosphorylated Cardiac Myosin-Binding Protein C (cMyBP-C) Activates Native Cardiac Thin Filaments within the C-Zone of Native Cardiac Thick Filaments Biophysical Journal. 104: 186a. DOI: 10.1016/J.Bpj.2012.11.1051 |
0.336 |
|
| 2012 |
Bhuiyan MS, Gulick J, Osinska H, Gupta M, Robbins J. Determination of the critical residues responsible for cardiac myosin binding protein C's interactions. Journal of Molecular and Cellular Cardiology. 53: 838-47. PMID 22982234 DOI: 10.1016/j.yjmcc.2012.08.028 |
0.331 |
|
| 2012 |
Previs MJ, Beck Previs S, Gulick J, Robbins J, Warshaw DM. Molecular mechanics of cardiac myosin-binding protein C in native thick filaments. Science (New York, N.Y.). 337: 1215-8. PMID 22923435 DOI: 10.1126/Science.1223602 |
0.326 |
|
| 2012 |
Weith AE, Previs MJ, Hoeprich GJ, Previs SB, Gulick J, Robbins J, Warshaw DM. The extent of cardiac myosin binding protein-C phosphorylation modulates actomyosin function in a graded manner. Journal of Muscle Research and Cell Motility. 33: 449-59. PMID 22752314 DOI: 10.1007/S10974-012-9312-Y |
0.321 |
|
| 2012 |
Lynch JM, Maillet M, Vanhoutte D, Schloemer A, Sargent MA, Blair NS, Lynch KA, Okada T, Aronow BJ, Osinska H, Prywes R, Lorenz JN, Mori K, Lawler J, Robbins J, et al. A thrombospondin-dependent pathway for a protective ER stress response. Cell. 149: 1257-68. PMID 22682248 DOI: 10.1016/J.Cell.2012.03.050 |
0.335 |
|
| 2012 |
Jeyaraj D, Haldar SM, Wan X, McCauley MD, Ripperger JA, Hu K, Lu Y, Eapen BL, Sharma N, Ficker E, Cutler MJ, Gulick J, Sanbe A, Robbins J, Demolombe S, et al. Circadian rhythms govern cardiac repolarization and arrhythmogenesis. Nature. 483: 96-9. PMID 22367544 DOI: 10.1038/Nature10852 |
0.423 |
|
| 2012 |
Sciarretta S, Zhai P, Shao D, Maejima Y, Robbins J, Volpe M, Condorelli G, Sadoshima J. Rheb is a critical regulator of autophagy during myocardial ischemia: pathophysiological implications in obesity and metabolic syndrome. Circulation. 125: 1134-46. PMID 22294621 DOI: 10.1161/CIRCULATIONAHA.111.078212 |
0.368 |
|
| 2012 |
Tranter M, Liu Y, He S, Gulick J, Ren X, Robbins J, Jones WK, Reineke TM. In vivo delivery of nucleic acids via glycopolymer vehicles affords therapeutic infarct size reduction in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 601-8. PMID 22186793 DOI: 10.1038/Mt.2011.267 |
0.334 |
|
| 2012 |
Haghighi K, Pritchard T, Bossuyt J, Waggoner JR, Yuan Q, Fan GC, Osinska H, Anjak A, Rubinstein J, Robbins J, Bers DM, Kranias EG. The human phospholamban Arg14-deletion mutant localizes to plasma membrane and interacts with the Na/K-ATPase. Journal of Molecular and Cellular Cardiology. 52: 773-82. PMID 22155237 DOI: 10.1016/J.Yjmcc.2011.11.012 |
0.425 |
|
| 2012 |
Weith A, Sadayappan S, Gulick J, Previs MJ, Vanburen P, Robbins J, Warshaw DM. Unique single molecule binding of cardiac myosin binding protein-C to actin and phosphorylation-dependent inhibition of actomyosin motility requires 17 amino acids of the motif domain. Journal of Molecular and Cellular Cardiology. 52: 219-27. PMID 21978630 DOI: 10.1016/J.Yjmcc.2011.09.019 |
0.321 |
|
| 2012 |
Michalek AJ, Gulick J, Robbins J, Warshaw DM. Mechanical Stability of the Cardiac Myosin Binding Protein-C (CMybP-C) Motif is Phosphorylation-Dependent Biophysical Journal. 102: 436a. DOI: 10.1016/J.Bpj.2011.11.2387 |
0.338 |
|
| 2012 |
Weith A, Hoeprich G, Gulick J, Robbins J, Warshaw D. Phosphorylation of Cardiac Myosin Binding Protein-C Acts as On/Off Switch to Modulate cMyBP-C's Inhibition of Actomyosin Power Generation in the Load-Clamp Laser Trap Assay Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.2386 |
0.302 |
|
| 2012 |
Tanner BC, Wang Y, Robbins J, Palmer BM. Cardiac Myosin Binding Protein-C Slows Cross-Bridge Kinetics and Increases MgATP Sensitivity Biophysical Journal. 102: 435a. DOI: 10.1016/j.bpj.2011.11.2381 |
0.333 |
|
| 2011 |
Robbins J. Twenty years of gene targeting: what we don't know. Circulation Research. 109: 722-3. PMID 21921271 DOI: 10.1161/CIRCRESAHA.111.249912 |
0.365 |
|
| 2011 |
Li J, Horak KM, Su H, Sanbe A, Robbins J, Wang X. Enhancement of proteasomal function protects against cardiac proteinopathy and ischemia/reperfusion injury in mice. The Journal of Clinical Investigation. 121: 3689-700. PMID 21841311 DOI: 10.1172/JCI45709 |
0.432 |
|
| 2011 |
McLendon PM, Robbins J. Desmin-related cardiomyopathy: an unfolding story. American Journal of Physiology. Heart and Circulatory Physiology. 301: H1220-8. PMID 21784990 DOI: 10.1152/ajpheart.00601.2011 |
0.391 |
|
| 2011 |
Li X, Chan TO, Myers V, Chowdhury I, Zhang XQ, Song J, Zhang J, Andrel J, Funakoshi H, Robbins J, Koch WJ, Hyslop T, Cheung JY, Feldman AM. Controlled and cardiac-restricted overexpression of the arginine vasopressin V1A receptor causes reversible left ventricular dysfunction through Gαq-mediated cell signaling. Circulation. 124: 572-81. PMID 21747049 DOI: 10.1161/Circulationaha.111.021352 |
0.365 |
|
| 2011 |
James J, Robbins J. At the source: treating heart failure by altering muscle motor function. Circulation Research. 109: 5-7. PMID 21700949 DOI: 10.1161/RES.0b013e31822765e2 |
0.451 |
|
| 2011 |
Pattison JS, Robbins J. Autophagy and proteotoxicity in cardiomyocytes. Autophagy. 7: 1259-60. PMID 21677510 DOI: 10.4161/auto.7.10.16882 |
0.418 |
|
| 2011 |
Pattison JS, Osinska H, Robbins J. Atg7 induces basal autophagy and rescues autophagic deficiency in CryABR120G cardiomyocytes. Circulation Research. 109: 151-60. PMID 21617129 DOI: 10.1161/CIRCRESAHA.110.237339 |
0.423 |
|
| 2011 |
Mun JY, Gulick J, Robbins J, Woodhead J, Lehman W, Craig R. Electron microscopy and 3D reconstruction of F-actin decorated with cardiac myosin-binding protein C (cMyBP-C). Journal of Molecular Biology. 410: 214-25. PMID 21601575 DOI: 10.1016/J.Jmb.2011.05.010 |
0.366 |
|
| 2011 |
Sadayappan S, Gulick J, Osinska H, Barefield D, Cuello F, Avkiran M, Lasko VM, Lorenz JN, Maillet M, Martin JL, Brown JH, Bers DM, Molkentin JD, James J, Robbins J. A critical function for Ser-282 in cardiac Myosin binding protein-C phosphorylation and cardiac function. Circulation Research. 109: 141-50. PMID 21597010 DOI: 10.1161/Circresaha.111.242560 |
0.371 |
|
| 2011 |
Stanley BA, Graham DR, James J, Mitsak M, Tarwater PM, Robbins J, Van Eyk JE. Altered myofilament stoichiometry in response to heart failure in a cardioprotective α-myosin heavy chain transgenic rabbit model. Proteomics. Clinical Applications. 5: 147-58. PMID 21365772 DOI: 10.1002/prca.201000116 |
0.426 |
|
| 2011 |
James J, Robbins J. Signaling and myosin-binding protein C. The Journal of Biological Chemistry. 286: 9913-9. PMID 21257752 DOI: 10.1074/jbc.R110.171801 |
0.409 |
|
| 2011 |
Weith A, Gulick J, VanBuren P, Robbins J, Warshaw DM. N-Terminal Fragment of Cardiac Myosin Binding Protein-C (CMYBP-C) Reduces Actomyosin Power Output in the Laser Trap Assay Biophysical Journal. 100: 4-4. DOI: 10.1016/J.Bpj.2010.12.2673 |
0.32 |
|
| 2010 |
Terrell D, Robbins J. Protein conformation-based disease: getting to the heart of the matter. Annual Review of Physiology. 72: 15-7. PMID 20148664 DOI: 10.1146/Annurev-Physiol-021909-135732 |
0.321 |
|
| 2010 |
Maillet M, Davis J, Auger-Messier M, York A, Osinska H, Piquereau J, Lorenz JN, Robbins J, Ventura-Clapier R, Molkentin JD. Heart-specific deletion of CnB1 reveals multiple mechanisms whereby calcineurin regulates cardiac growth and function. The Journal of Biological Chemistry. 285: 6716-24. PMID 20037164 DOI: 10.1074/Jbc.M109.056143 |
0.486 |
|
| 2010 |
Bardswell SC, Cuello F, Rowland AJ, Sadayappan S, Robbins J, Gautel M, Walker JW, Kentish JC, Avkiran M. Distinct sarcomeric substrates are responsible for protein kinase D-mediated regulation of cardiac myofilament Ca2+ sensitivity and cross-bridge cycling. The Journal of Biological Chemistry. 285: 5674-82. PMID 20018870 DOI: 10.1074/Jbc.M109.066456 |
0.367 |
|
| 2010 |
Rice R, Guinto P, Dowell-Martino C, He H, Hoyer K, Krenz M, Robbins J, Ingwall JS, Tardiff JC. Cardiac myosin heavy chain isoform exchange alters the phenotype of cTnT-related cardiomyopathies in mouse hearts. Journal of Molecular and Cellular Cardiology. 48: 979-88. PMID 20004663 DOI: 10.1016/J.Yjmcc.2009.11.018 |
0.427 |
|
| 2010 |
James J, Hor K, Moga MA, Martin LA, Robbins J. Effects of myosin heavy chain manipulation in experimental heart failure. Journal of Molecular and Cellular Cardiology. 48: 999-1006. PMID 19854200 DOI: 10.1016/j.yjmcc.2009.10.013 |
0.407 |
|
| 2010 |
Heineke J, Wollert KC, Osinska H, Sargent MA, York AJ, Robbins J, Molkentin JD. Calcineurin protects the heart in a murine model of dilated cardiomyopathy. Journal of Molecular and Cellular Cardiology. 48: 1080-7. PMID 19854199 DOI: 10.1016/J.Yjmcc.2009.10.012 |
0.446 |
|
| 2010 |
Weith AE, Sadayappan S, VanBuren P, Robbins J, Warshaw DM. N-Terminal Fragments of Cardiac Myosin Binding Protein-C Inhibit Actomyosin Motility by Tethering Actin Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.4151 |
0.33 |
|
| 2009 |
Nakayama H, Bodi I, Correll RN, Chen X, Lorenz J, Houser SR, Robbins J, Schwartz A, Molkentin JD. alpha1G-dependent T-type Ca2+ current antagonizes cardiac hypertrophy through a NOS3-dependent mechanism in mice. The Journal of Clinical Investigation. 119: 3787-96. PMID 19920353 DOI: 10.1172/Jci39724 |
0.4 |
|
| 2009 |
Suzuki T, Palmer BM, James J, Wang Y, Chen Z, VanBuren P, Maughan DW, Robbins J, LeWinter MM. Effects of cardiac myosin isoform variation on myofilament function and crossbridge kinetics in transgenic rabbits. Circulation. Heart Failure. 2: 334-41. PMID 19808357 DOI: 10.1161/CIRCHEARTFAILURE.108.802298 |
0.395 |
|
| 2009 |
Xiang FL, Lu X, Hammoud L, Zhu P, Chidiac P, Robbins J, Feng Q. Cardiomyocyte-specific overexpression of human stem cell factor improves cardiac function and survival after myocardial infarction in mice. Circulation. 120: 1065-74, 9 p followi. PMID 19738140 DOI: 10.1161/Circulationaha.108.839068 |
0.392 |
|
| 2009 |
Huang H, Macgillivray C, Kwon HS, Lammerding J, Robbins J, Lee RT, So P. Three-dimensional cardiac architecture determined by two-photon microtomy. Journal of Biomedical Optics. 14: 044029. PMID 19725740 DOI: 10.1117/1.3200939 |
0.376 |
|
| 2009 |
Nakamura T, Gulick J, Pratt R, Robbins J. Noonan syndrome is associated with enhanced pERK activity, the repression of which can prevent craniofacial malformations. Proceedings of the National Academy of Sciences of the United States of America. 106: 15436-41. PMID 19706403 DOI: 10.1073/pnas.0903302106 |
0.367 |
|
| 2009 |
Nakamura T, Gulick J, Colbert MC, Robbins J. Protein tyrosine phosphatase activity in the neural crest is essential for normal heart and skull development. Proceedings of the National Academy of Sciences of the United States of America. 106: 11270-5. PMID 19541608 DOI: 10.1073/pnas.0902230106 |
0.409 |
|
| 2009 |
Gulick J, Robbins J. Cell-type-specific transgenesis in the mouse. Methods in Molecular Biology (Clifton, N.J.). 561: 91-104. PMID 19504066 DOI: 10.1007/978-1-60327-019-9_6 |
0.332 |
|
| 2009 |
Nicolaou P, Rodriguez P, Ren X, Zhou X, Qian J, Sadayappan S, Mitton B, Pathak A, Robbins J, Hajjar RJ, Jones K, Kranias EG. Inducible expression of active protein phosphatase-1 inhibitor-1 enhances basal cardiac function and protects against ischemia/reperfusion injury. Circulation Research. 104: 1012-20. PMID 19299645 DOI: 10.1161/Circresaha.108.189811 |
0.414 |
|
| 2009 |
Maloyan A, Osinska H, Lammerding J, Lee RT, Cingolani OH, Kass DA, Lorenz JN, Robbins J. Biochemical and mechanical dysfunction in a mouse model of desmin-related myopathy. Circulation Research. 104: 1021-8. PMID 19299643 DOI: 10.1161/CIRCRESAHA.108.193516 |
0.407 |
|
| 2009 |
Wu X, Chang B, Blair NS, Sargent M, York AJ, Robbins J, Shull GE, Molkentin JD. Plasma membrane Ca2+-ATPase isoform 4 antagonizes cardiac hypertrophy in association with calcineurin inhibition in rodents. The Journal of Clinical Investigation. 119: 976-85. PMID 19287093 DOI: 10.1172/Jci36693 |
0.377 |
|
| 2009 |
Sadayappan S, Gulick J, Klevitsky R, Lorenz JN, Sargent M, Molkentin JD, Robbins J. Cardiac myosin binding protein-C phosphorylation in a {beta}-myosin heavy chain background. Circulation. 119: 1253-62. PMID 19237661 DOI: 10.1161/Circulationaha.108.798983 |
0.445 |
|
| 2009 |
Waggoner JR, Ginsburg KS, Mitton B, Haghighi K, Robbins J, Bers DM, Kranias EG. Phospholamban overexpression in rabbit ventricular myocytes does not alter sarcoplasmic reticulum Ca transport. American Journal of Physiology. Heart and Circulatory Physiology. 296: H698-703. PMID 19112098 DOI: 10.1152/Ajpheart.00272.2008 |
0.352 |
|
| 2009 |
Scruggs SB, Hinken AC, Thawornkaiwong A, Robbins J, Walker LA, de Tombe PP, Geenen DL, Buttrick PM, Solaro RJ. Ablation of ventricular myosin regulatory light chain phosphorylation in mice causes cardiac dysfunction in situ and affects neighboring myofilament protein phosphorylation. The Journal of Biological Chemistry. 284: 5097-106. PMID 19106098 DOI: 10.1074/Jbc.M807414200 |
0.395 |
|
| 2008 |
Krenz M, Gulick J, Osinska HE, Colbert MC, Molkentin JD, Robbins J. Role of ERK1/2 signaling in congenital valve malformations in Noonan syndrome. Proceedings of the National Academy of Sciences of the United States of America. 105: 18930-5. PMID 19017799 DOI: 10.1073/Pnas.0806556105 |
0.403 |
|
| 2008 |
Jaleel N, Nakayama H, Chen X, Kubo H, MacDonnell S, Zhang H, Berretta R, Robbins J, Cribbs L, Molkentin JD, Houser SR. Ca2+ influx through T- and L-type Ca2+ channels have different effects on myocyte contractility and induce unique cardiac phenotypes. Circulation Research. 103: 1109-19. PMID 18832749 DOI: 10.1161/Circresaha.108.185611 |
0.342 |
|
| 2008 |
Yano N, Tseng A, Zhao TC, Robbins J, Padbury JF, Tseng YT. Temporally controlled overexpression of cardiac-specific PI3Kalpha induces enhanced myocardial contractility--a new transgenic model. American Journal of Physiology. Heart and Circulatory Physiology. 295: H1690-4. PMID 18723766 DOI: 10.1152/Ajpheart.00531.2008 |
0.385 |
|
| 2008 |
Pattison JS, Robbins J. Protein misfolding and cardiac disease: establishing cause and effect. Autophagy. 4: 821-3. PMID 18612262 DOI: 10.4161/Auto.6502 |
0.416 |
|
| 2008 |
Moga MA, Nakamura T, Robbins J. Genetic approaches for changing the heart and dissecting complex syndromes. Journal of Molecular and Cellular Cardiology. 45: 148-55. PMID 18601931 DOI: 10.1016/j.yjmcc.2008.06.002 |
0.378 |
|
| 2008 |
Pattison JS, Sanbe A, Maloyan A, Osinska H, Klevitsky R, Robbins J. Cardiomyocyte expression of a polyglutamine preamyloid oligomer causes heart failure. Circulation. 117: 2743-51. PMID 18490523 DOI: 10.1161/CIRCULATIONAHA.107.750232 |
0.382 |
|
| 2008 |
Lowey S, Lesko LM, Rovner AS, Hodges AR, White SL, Low RB, Rincon M, Gulick J, Robbins J. Functional effects of the hypertrophic cardiomyopathy R403Q mutation are different in an alpha- or beta-myosin heavy chain backbone. The Journal of Biological Chemistry. 283: 20579-89. PMID 18480046 DOI: 10.1074/jbc.M800554200 |
0.356 |
|
| 2008 |
Sadayappan S, Robbins J. The death of transcriptional chauvinism in the control and regulation of cardiac contractility. Annals of the New York Academy of Sciences. 1123: 1-9. PMID 18375572 DOI: 10.1196/annals.1420.002 |
0.401 |
|
| 2008 |
Millay DP, Sargent MA, Osinska H, Baines CP, Barton ER, Vuagniaux G, Sweeney HL, Robbins J, Molkentin JD. Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy. Nature Medicine. 14: 442-7. PMID 18345011 DOI: 10.1038/Nm1736 |
0.36 |
|
| 2008 |
Pinz I, Ostroy SE, Hoyer K, Osinska H, Robbins J, Molkentin JD, Ingwall JS. Calcineurin-induced energy wasting in a transgenic mouse model of heart failure. American Journal of Physiology. Heart and Circulatory Physiology. 294: H1459-66. PMID 18192216 DOI: 10.1152/Ajpheart.00911.2007 |
0.395 |
|
| 2008 |
Wolf CM, Arad M, Ahmad F, Sanbe A, Bernstein SA, Toka O, Konno T, Morley G, Robbins J, Seidman JG, Seidman CE, Berul CI. Reversibility of PRKAG2 glycogen-storage cardiomyopathy and electrophysiological manifestations. Circulation. 117: 144-54. PMID 18158359 DOI: 10.1161/CIRCULATIONAHA.107.726752 |
0.451 |
|
| 2008 |
Sadayappan S, Finley N, Howarth JW, Osinska H, Klevitsky R, Lorenz JN, Rosevear PR, Robbins J. Role of the acidic N' region of cardiac troponin I in regulating myocardial function. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 1246-57. PMID 17984178 DOI: 10.1096/Fj.07-9458Com |
0.399 |
|
| 2008 |
Pattison JS, Waggoner JR, James J, Martin L, Gulick J, Osinska H, Klevitsky R, Kranias EG, Robbins J. Phospholamban overexpression in transgenic rabbits. Transgenic Research. 17: 157-70. PMID 17882530 DOI: 10.1007/S11248-007-9139-2 |
0.448 |
|
| 2008 |
Pinz I, Robbins J, Rajasekaran NS, Benjamin IJ, Ingwall JS. Unmasking different mechanical and energetic roles for the small heat shock proteins CryAB and HSPB2 using genetically modified mouse hearts. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 84-92. PMID 17846079 DOI: 10.1096/fj.07-8130com |
0.419 |
|
| 2008 |
Chen L, Zhao X, Reinhardt H, Gelpi R, Robbins J, Vatner DE, Vatner SF. Overexpressed Cardiac Gs alpha Protects Against Myocardial Ischemic Injury in Conscious Rabbits The Faseb Journal. 22: 51-51. DOI: 10.1096/FASEBJ.22.2_SUPPLEMENT.51 |
0.322 |
|
| 2007 |
Nagayama T, Takimoto E, Sadayappan S, Mudd JO, Seidman JG, Robbins J, Kass DA. Control of in vivo left ventricular [correction] contraction/relaxation kinetics by myosin binding protein C: protein kinase A phosphorylation dependent and independent regulation. Circulation. 116: 2399-408. PMID 17984378 DOI: 10.1161/CIRCULATIONAHA.107.706523 |
0.424 |
|
| 2007 |
Heineke J, Auger-Messier M, Xu J, Oka T, Sargent MA, York A, Klevitsky R, Vaikunth S, Duncan SA, Aronow BJ, Robbins J, Crombleholme TM, Cromblehol TM, Molkentin JD. Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart. The Journal of Clinical Investigation. 117: 3198-210. PMID 17975667 DOI: 10.1172/Jci32573 |
0.432 |
|
| 2007 |
Hambleton M, York A, Sargent MA, Kaiser RA, Lorenz JN, Robbins J, Molkentin JD. Inducible and myocyte-specific inhibition of PKCalpha enhances cardiac contractility and protects against infarction-induced heart failure. American Journal of Physiology. Heart and Circulatory Physiology. 293: H3768-71. PMID 17921332 DOI: 10.1152/Ajpheart.00486.2007 |
0.46 |
|
| 2007 |
Diwan A, Krenz M, Syed FM, Wansapura J, Ren X, Koesters AG, Li H, Kirshenbaum LA, Hahn HS, Robbins J, Jones WK, Dorn GW. Inhibition of ischemic cardiomyocyte apoptosis through targeted ablation of Bnip3 restrains postinfarction remodeling in mice. The Journal of Clinical Investigation. 117: 2825-33. PMID 17909626 DOI: 10.1172/Jci32490 |
0.379 |
|
| 2007 |
Purcell NH, Wilkins BJ, York A, Saba-El-Leil MK, Meloche S, Robbins J, Molkentin JD. Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo. Proceedings of the National Academy of Sciences of the United States of America. 104: 14074-9. PMID 17709754 DOI: 10.1073/Pnas.0610906104 |
0.423 |
|
| 2007 |
Hsieh PC, Segers VF, Davis ME, MacGillivray C, Gannon J, Molkentin JD, Robbins J, Lee RT. Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injury. Nature Medicine. 13: 970-4. PMID 17660827 DOI: 10.1038/Nm1618 |
0.345 |
|
| 2007 |
Nakamura T, Colbert M, Krenz M, Molkentin JD, Hahn HS, Dorn GW, Robbins J. Mediating ERK 1/2 signaling rescues congenital heart defects in a mouse model of Noonan syndrome. The Journal of Clinical Investigation. 117: 2123-32. PMID 17641779 DOI: 10.1172/Jci30756 |
0.466 |
|
| 2007 |
Yasuda S, Coutu P, Sadayappan S, Robbins J, Metzger JM. Cardiac transgenic and gene transfer strategies converge to support an important role for troponin I in regulating relaxation in cardiac myocytes. Circulation Research. 101: 377-86. PMID 17615373 DOI: 10.1161/Circresaha.106.145557 |
0.393 |
|
| 2007 |
Krenz M, Sadayappan S, Osinska HE, Henry JA, Beck S, Warshaw DM, Robbins J. Distribution and structure-function relationship of myosin heavy chain isoforms in the adult mouse heart. The Journal of Biological Chemistry. 282: 24057-64. PMID 17575272 DOI: 10.1074/jbc.M704574200 |
0.38 |
|
| 2007 |
Oka T, Xu J, Kaiser RA, Melendez J, Hambleton M, Sargent MA, Lorts A, Brunskill EW, Dorn GW, Conway SJ, Aronow BJ, Robbins J, Molkentin JD. Genetic manipulation of periostin expression reveals a role in cardiac hypertrophy and ventricular remodeling. Circulation Research. 101: 313-21. PMID 17569887 DOI: 10.1016/J.Cardfail.2007.06.236 |
0.362 |
|
| 2007 |
Maloyan A, Gulick J, Glabe CG, Kayed R, Robbins J. Exercise reverses preamyloid oligomer and prolongs survival in alphaB-crystallin-based desmin-related cardiomyopathy. Proceedings of the National Academy of Sciences of the United States of America. 104: 5995-6000. PMID 17389375 DOI: 10.1073/Pnas.0609202104 |
0.349 |
|
| 2007 |
Galvez AS, Diwan A, Odley AM, Hahn HS, Osinska H, Melendez JG, Robbins J, Lynch RA, Marreez Y, Dorn GW. Cardiomyocyte degeneration with calpain deficiency reveals a critical role in protein homeostasis Circulation Research. 100: 1071-1078. PMID 17332428 DOI: 10.1161/01.Res.0000261938.28365.11 |
0.424 |
|
| 2007 |
Yutzey KE, Robbins J. Principles of genetic murine models for cardiac disease. Circulation. 115: 792-9. PMID 17296868 DOI: 10.1161/Circulationaha.106.682534 |
0.412 |
|
| 2007 |
Nishizawa T, Shen Y, Rossi F, Hong C, Robbins J, Ishikawa Y, Sadoshima J, Vatner DE, Vatner SF. Altered autonomic control in conscious transgenic rabbits with overexpressed cardiac Gsα American Journal of Physiology-Heart and Circulatory Physiology. 292: 971-975. PMID 17287453 DOI: 10.1152/Ajpheart.00791.2006 |
0.397 |
|
| 2007 |
Hoyer K, Krenz M, Robbins J, Ingwall JS. Shifts in the myosin heavy chain isozymes in the mouse heart result in increased energy efficiency. Journal of Molecular and Cellular Cardiology. 42: 214-21. PMID 17054980 DOI: 10.1016/j.yjmcc.2006.08.116 |
0.42 |
|
| 2007 |
Diwan A, Krenz M, Wansapura J, Ren X, Dunn RS, Odley A, Robbins J, Jones WK, Dorn G. Inhibition of Cardiomyocyte Apoptosis by Targeted Ablation of Bnip3 Restrains Post-Infarction Ventricular Remodeling Journal of Cardiac Failure. 13: S71. DOI: 10.1016/j.cardfail.2007.06.310 |
0.308 |
|
| 2006 |
Wang X, Robbins J. Heart Failure and Protein Quality Control Circulation Research. 99: 1315-1328. PMID 17158347 DOI: 10.1161/01.Res.0000252342.61447.A2 |
0.396 |
|
| 2006 |
Funakoshi H, Chan TO, Good JC, Libonati JR, Piuhola J, Chen X, MacDonnell SM, Lee LL, Herrmann DE, Zhang J, Martini J, Palmer TM, Sanbe A, Robbins J, Houser SR, et al. Regulated overexpression of the A1-adenosine receptor in mice results in adverse but reversible changes in cardiac morphology and function. Circulation. 114: 2240-50. PMID 17088462 DOI: 10.1161/Circulationaha.106.620211 |
0.356 |
|
| 2006 |
Sadayappan S, Osinska H, Klevitsky R, Lorenz JN, Sargent M, Molkentin JD, Seidman CE, Seidman JG, Robbins J. Cardiac myosin binding protein C phosphorylation is cardioprotective. Proceedings of the National Academy of Sciences of the United States of America. 103: 16918-23. PMID 17075052 DOI: 10.1073/pnas.0607069103 |
0.401 |
|
| 2006 |
Wang H, Grant JE, Doede CM, Sadayappan S, Robbins J, Walker JW. PKC-betaII sensitizes cardiac myofilaments to Ca2+ by phosphorylating troponin I on threonine-144. Journal of Molecular and Cellular Cardiology. 41: 823-33. PMID 17010989 DOI: 10.1016/J.Yjmcc.2006.08.016 |
0.354 |
|
| 2006 |
Dias FA, Walker LA, Arteaga GM, Walker JS, Vijayan K, Peña JR, Ke Y, Fogaca RT, Sanbe A, Robbins J, Wolska BM. The effect of myosin regulatory light chain phosphorylation on the frequency-dependent regulation of cardiac function. Journal of Molecular and Cellular Cardiology. 41: 330-9. PMID 16806259 DOI: 10.1016/j.yjmcc.2006.05.012 |
0.375 |
|
| 2006 |
Nakamura T, Colbert MC, Robbins J. Neural crest cells retain multipotential characteristics in the developing valves and label the cardiac conduction system. Circulation Research. 98: 1547-54. PMID 16709902 DOI: 10.1161/01.RES.0000227505.19472.69 |
0.384 |
|
| 2006 |
Nishizawa T, Vatner SF, Hong C, Shen Y, Hardt SE, Robbins J, Ishikawa Y, Sadoshima J, Vatner DE. Overexpressed cardiac Gsα in rabbits Journal of Molecular and Cellular Cardiology. 41: 44-50. PMID 16678849 DOI: 10.1016/J.Yjmcc.2006.03.008 |
0.426 |
|
| 2006 |
Tallini YN, Ohkura M, Choi BR, Ji G, Imoto K, Doran R, Lee J, Plan P, Wilson J, Xin HB, Sanbe A, Gulick J, Mathai J, Robbins J, Salama G, et al. Imaging cellular signals in the heart in vivo: Cardiac expression of the high-signal Ca2+ indicator GCaMP2. Proceedings of the National Academy of Sciences of the United States of America. 103: 4753-8. PMID 16537386 DOI: 10.1073/Pnas.0509378103 |
0.407 |
|
| 2006 |
Gaffin RD, Gokulan K, Sacchettini JC, Hewett TE, Klevitsky R, Robbins J, Sarin V, Zawieja DC, Meininger GA, Muthuchamy M. Changes in end-to-end interactions of tropomyosin affect mouse cardiac muscle dynamics. American Journal of Physiology. Heart and Circulatory Physiology. 291: H552-63. PMID 16501024 DOI: 10.1152/Ajpheart.00688.2005 |
0.365 |
|
| 2005 |
Gulick J, Robbins J. Regulation of transgene expression using tetracycline. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 23.12. PMID 18265363 DOI: 10.1002/0471142727.mb2312s71 |
0.331 |
|
| 2005 |
Maloyan A, Sanbe A, Osinska H, Westfall M, Robinson D, Imahashi K, Murphy E, Robbins J. Mitochondrial dysfunction and apoptosis underlie the pathogenic process in alpha-B-crystallin desmin-related cardiomyopathy. Circulation. 112: 3451-61. PMID 16316967 DOI: 10.1161/CIRCULATIONAHA.105.572552 |
0.366 |
|
| 2005 |
Yutzey KE, Colbert M, Robbins J. Ras-related signaling pathways in valve development: ebb and flow. Physiology (Bethesda, Md.). 20: 390-7. PMID 16287988 DOI: 10.1152/Physiol.00035.2005 |
0.342 |
|
| 2005 |
Sadayappan S, Gulick J, Osinska H, Martin LA, Hahn HS, Dorn GW, Klevitsky R, Seidman CE, Seidman JG, Robbins J. Cardiac myosin-binding protein-C phosphorylation and cardiac function. Circulation Research. 97: 1156-63. PMID 16224063 DOI: 10.1161/01.Res.0000190605.79013.4D |
0.438 |
|
| 2005 |
Krenz M, Yutzey KE, Robbins J. Noonan syndrome mutation Q79R in Shp2 increases proliferation of valve primordia mesenchymal cells via extracellular signal-regulated kinase 1/2 signaling. Circulation Research. 97: 813-20. PMID 16166557 DOI: 10.1161/01.Res.0000186194.06514.B0 |
0.345 |
|
| 2005 |
Sanbe A, Osinska H, Villa C, Gulick J, Klevitsky R, Glabe CG, Kayed R, Robbins J. Reversal of amyloid-induced heart disease in desmin-related cardiomyopathy. Proceedings of the National Academy of Sciences of the United States of America. 102: 13592-7. PMID 16155124 DOI: 10.1073/Pnas.0503324102 |
0.425 |
|
| 2005 |
Miller MS, Palmer BM, Ruch S, Martin LA, Farman GP, Wang Y, Robbins J, Irving TC, Maughan DW. The essential light chain N-terminal extension alters force and fiber kinetics in mouse cardiac muscle. The Journal of Biological Chemistry. 280: 34427-34. PMID 16085933 DOI: 10.1074/Jbc.M508430200 |
0.391 |
|
| 2005 |
Gard JJ, Yamada K, Green KG, Eloff BC, Rosenbaum DS, Wang X, Robbins J, Schuessler RB, Yamada KA, Saffitz JE. Remodeling of gap junctions and slow conduction in a mouse model of desmin-related cardiomyopathy Cardiovascular Research. 67: 539-547. PMID 15913582 DOI: 10.1016/J.Cardiores.2005.04.004 |
0.391 |
|
| 2005 |
James J, Martin L, Krenz M, Quatman C, Jones F, Klevitsky R, Gulick J, Robbins J. Forced Expression of α-Myosin Heavy Chain in the Rabbit Ventricle Results in Cardioprotection Under Cardiomyopathic Conditions Circulation. 111: 2339-2346. PMID 15867177 DOI: 10.1161/01.Cir.0000164233.09448.B1 |
0.353 |
|
| 2005 |
Sanbe A, James J, Tuzcu V, Nas S, Martin L, Gulick J, Osinska H, Sakthivel S, Klevitsky R, Ginsburg KS, Bers DM, Zinman B, Lakatta EG, Robbins J. Transgenic rabbit model for human troponin I-based hypertrophic cardiomyopathy. Circulation. 111: 2330-8. PMID 15867176 DOI: 10.1161/01.Cir.0000164234.24957.75 |
0.334 |
|
| 2005 |
Kruger M, Zittrich S, Redwood C, Blaudeck N, James J, Robbins J, Pfitzer G, Stehle R. Effects of the mutation R145G in human cardiac troponin I on the kinetics of the contraction-relaxation cycle in isolated cardiac myofibrils. The Journal of Physiology. 564: 347-357. PMID 15718266 DOI: 10.1113/Jphysiol.2004.079095 |
0.366 |
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| 2005 |
Sakthivel S, Finley NL, Rosevear PR, Lorenz JN, Gulick J, Kim S, VanBuren P, Martin LA, Robbins J. In vivo and in vitro analysis of cardiac troponin I phosphorylation. The Journal of Biological Chemistry. 280: 703-14. PMID 15507454 DOI: 10.1074/Jbc.M409513200 |
0.394 |
|
| 2005 |
Nakayama M, Yan X, Price RL, Borg TK, Ito K, Sanbe A, Robbins J, Lorell BH. Chronic ventricular myocyte-specific overexpression of angiotensin II type 2 receptor results in intrinsic myocyte contractile dysfunction American Journal of Physiology - Heart and Circulatory Physiology. 288: H317-H327. PMID 15374832 DOI: 10.1152/Ajpheart.00957.2003 |
0.374 |
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| 2004 |
Kumar A, Crawford K, Flick R, Klevitsky R, Lorenz JN, Bove KE, Robbins J, Lessard JL. Transgenic overexpression of cardiac actin in the mouse heart suggests coregulation of cardiac, skeletal and vascular actin expression. Transgenic Research. 13: 531-540. PMID 15672834 DOI: 10.1007/S11248-004-2823-6 |
0.465 |
|
| 2004 |
Krenz M, Robbins J. Impact of beta-myosin heavy chain expression on cardiac function during stress. Journal of the American College of Cardiology. 44: 2390-2397. PMID 15607403 DOI: 10.1016/J.Jacc.2004.09.044 |
0.436 |
|
| 2004 |
Syed F, Odley A, Hahn HS, Brunskill EW, Lynch RA, Marreez Y, Sanbe A, Robbins J, Dorn GW. Physiological growth synergizes with pathological genes in experimental cardiomyopathy Circulation Research. 95: 1200-1206. PMID 15539635 DOI: 10.1161/01.RES.0000150366.08972.7f |
0.427 |
|
| 2004 |
Gaffin RD, Tong CW, Zawieja DC, Hewett TE, Klevitsky R, Robbins J, Muthuchamy M. Charged residue alterations in the inner-core domain and carboxy-terminus of alpha-tropomyosin differentially affect mouse cardiac muscle contractility. The Journal of Physiology. 561: 777-91. PMID 15486021 DOI: 10.1113/Jphysiol.2004.070631 |
0.316 |
|
| 2004 |
Sanbe A, Osinska H, Saffitz JE, Glabe CG, Kayed R, Maloyan A, Robbins J. Desmin-related cardiomyopathy in transgenic mice: a cardiac amyloidosis. Proceedings of the National Academy of Sciences of the United States of America. 101: 10132-6. PMID 15220483 DOI: 10.1073/Pnas.0401900101 |
0.396 |
|
| 2004 |
Robbins J. Genetic modification of the heart: exploring necessity and sufficiency in the past 10 years. Journal of Molecular and Cellular Cardiology. 36: 643-652. PMID 15135658 DOI: 10.1016/J.Yjmcc.2004.02.012 |
0.421 |
|
| 2004 |
Odley A, Hahn HS, Lynch RA, Marreez Y, Osinska H, Robbins J, Dorn GW. Regulation of cardiac contractility by Rab4-modulated β2-adrenergic receptor recycling Proceedings of the National Academy of Sciences of the United States of America. 101: 7082-7087. PMID 15105445 DOI: 10.1073/Pnas.0308335101 |
0.438 |
|
| 2004 |
Song Q, Young KB, Chu G, Gulick J, Gerst M, Grupp IL, Robbins J, Kranias EG. Overexpression of phospholamban in slow-twitch skeletal muscle is associated with depressed contractile function and muscle remodeling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 974-6. PMID 15059971 DOI: 10.1096/Fj.03-1058Fje |
0.329 |
|
| 2004 |
Wei L, Taffet GE, Khoury DS, Bo J, Li Y, Yatani A, Delaughter MC, Klevitsky R, Hewett TE, Robbins J, Michael LH, Schneider MD, Entman ML, Schwartz RJ. Disruption of Rho signaling results in progressive atrioventricular conduction defects while ventricular function remains preserved. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 857-9. PMID 15033930 DOI: 10.1096/Fj.03-0664Fje |
0.334 |
|
| 2004 |
Braz JC, Gregory K, Pathak A, Zhao W, Sahin B, Klevitsky R, Kimball TF, Lorenz JN, Nairn AC, Liggett SB, Bodi I, Wang S, Schwartz A, Lakatta EG, DePaoli-Roach AA, ... Robbins J, et al. PKC-alpha regulates cardiac contractility and propensity toward heart failure. Nature Medicine. 10: 248-54. PMID 14966518 DOI: 10.1038/Nm1000 |
0.302 |
|
| 2004 |
Gaffin RD, Gokulan K, Sacchettini JC, Hewett T, Klevitsky R, Robbins J, Muthuchamy M. Charged residue changes in the carboxy-terminus of alpha-tropomyosin alter mouse cardiac muscle contractility. The Journal of Physiology. 556: 531-43. PMID 14766940 DOI: 10.1113/Jphysiol.2003.058487 |
0.351 |
|
| 2003 |
Wang X, Klevitsky R, Huang W, Glasford J, Li F, Robbins J. αB-Crystallin Modulates Protein Aggregation of Abnormal Desmin Circulation Research. 93: 998-1005. PMID 14576194 DOI: 10.1161/01.Res.0000102401.77712.Ed |
0.454 |
|
| 2003 |
Yan X, Price RL, Nakayama M, Ito K, Schuldt AJT, Manning WJ, Sanbe A, Borg TK, Robbins J, Lorell BH. Ventricular-specific expression of angiotensin II type 2 receptors causes dilated cardiomyopathy and heart failure in transgenic mice American Journal of Physiology - Heart and Circulatory Physiology. 285: H2179-H2187. PMID 12869376 DOI: 10.1152/Ajpheart.00361.2003 |
0.422 |
|
| 2003 |
Dorn GW, Robbins J, Sugden PH. Phenotyping hypertrophy: eschew obfuscation. Circulation Research. 92: 1171-5. PMID 12805233 DOI: 10.1161/01.Res.0000077012.11088.Bc |
0.415 |
|
| 2003 |
Ishibashi Y, Takahashi M, Isomatsu Y, Qiao F, Iijima Y, Shiraishi H, Simsic JM, Baicu CF, Robbins J, Zile MR, Cooper G. Role of microtubules versus myosin heavy chain isoforms in contractile dysfunction of hypertrophied murine cardiocytes. American Journal of Physiology. Heart and Circulatory Physiology. 285: H1270-85. PMID 12750067 DOI: 10.1152/ajpheart.00654.2002 |
0.311 |
|
| 2003 |
Krenz M, Sanbe A, Bouyer-Dalloz F, Gulick J, Klevitsky R, Hewett TE, Osinska HE, Lorenz JN, Brosseau C, Federico A, Alpert NR, Warshaw DM, Perryman MB, Helmke SM, Robbins J. Analysis of myosin heavy chain functionality in the heart. The Journal of Biological Chemistry. 278: 17466-74. PMID 12626511 DOI: 10.1074/Jbc.M210804200 |
0.405 |
|
| 2003 |
Sanbe A, Gulick J, Hanks MC, Liang Q, Osinska H, Robbins J. Reengineering inducible cardiac-specific transgenesis with an attenuated myosin heavy chain promoter Circulation Research. 92: 609-616. PMID 12623879 DOI: 10.1161/01.RES.0000065442.64694.9F |
0.422 |
|
| 2002 |
Wang X, Osinska H, Gerdes AM, Robbins J. Desmin filaments and cardiac disease: Establishing causality Journal of Cardiac Failure. 8. PMID 12555134 DOI: 10.1054/Jcaf.2002.129279 |
0.482 |
|
| 2002 |
Hahn HS, Yussman MG, Toyokawa T, Marreez Y, Barrett TJ, Hilty KC, Osinska H, Robbins J, Dorn GW. Ischemic protection and myofibrillar cardiomyopathy: Dose-dependent effects of in vivo δPKC inhibition Circulation Research. 91: 741-748. PMID 12386152 DOI: 10.1161/01.Res.0000037091.64492.69 |
0.493 |
|
| 2002 |
Robbins J, Benson DW. Structure-Function Relationships in Myosin Binding Protein-C: Taking Off the Blinders and Collaring Hypertrophic Cardiomyopathy Circulation Research. 91: 656-658. PMID 12386140 DOI: 10.1161/01.Res.0000039080.47825.Ca |
0.352 |
|
| 2002 |
Alpert NR, Brosseau C, Federico A, Krenz M, Robbins J, Warshaw DM. Molecular mechanics of mouse cardiac myosin isoforms. American Journal of Physiology-Heart and Circulatory Physiology. 283. PMID 12234796 DOI: 10.1152/Ajpheart.00274.2002 |
0.333 |
|
| 2002 |
James J, Zhang Y, Wright K, Witt S, Glascock E, Osinska H, Klevitsky R, Martin L, Yager K, Sanbe A, Robbins J. Transgenic rabbits expressing mutant essential light chain do not develop hypertrophic cardiomyopathy. Journal of Molecular and Cellular Cardiology. 34: 873-882. PMID 12099725 DOI: 10.1006/Jmcc.2002.2025 |
0.389 |
|
| 2002 |
Chu G, Carr AN, Young KB, Lester JW, Yatani A, Sanbe A, Colbert MC, Schwartz SM, Frank KF, Lampe PD, Robbins J, Molkentin JD, Kranias EG. Enhanced myocyte contractility and Ca2+ handling in a calcineurin transgenic model of heart failure. Cardiovascular Research. 54: 105-16. PMID 12062367 DOI: 10.1016/S0008-6363(02)00230-4 |
0.416 |
|
| 2001 |
Wu G, Yussman MG, Barrett TJ, Hahn HS, Osinska H, Hilliard GM, Wang X, Toyokawa T, Yatani A, Lynch RA, Robbins J, Dorn GW. Increased myocardial Rab GTPase expression: A consequence and cause of cardiomyopathy Circulation Research. 89: 1130-1137. PMID 11739277 DOI: 10.1161/HH2401.100427 |
0.476 |
|
| 2001 |
Yang Q, Osinska H, Klevitsky R, Robbins J. Phenotypic Deficits in Mice Expressing a Myosin Binding Protein C Lacking the Titin and Myosin Binding Domains Journal of Molecular and Cellular Cardiology. 33: 1649-1658. PMID 11549344 DOI: 10.1006/Jmcc.2001.1417 |
0.411 |
|
| 2001 |
Schwartzbauer G, Robbins J. The Tumor Suppressor Gene PTEN Can Regulate Cardiac Hypertrophy and Survival Journal of Biological Chemistry. 276: 35786-35793. PMID 11448956 DOI: 10.1074/Jbc.M102479200 |
0.412 |
|
| 2001 |
Wang X, Osinska H, Klevitsky R, Gerdes AM, Nieman M, Lorenz J, Hewett T, Robbins J. Expression of R120G-alphaB-crystallin causes aberrant desmin and alphaB-crystallin aggregation and cardiomyopathy in mice. Circulation Research. 89: 84-91. PMID 11440982 DOI: 10.1161/Hh1301.092688 |
0.381 |
|
| 2001 |
Sanbe A, Gulick J, Fewell J, Robbins J. Examining the in Vivo Role of the Amino Terminus of the Essential Myosin Light Chain Journal of Biological Chemistry. 276: 32682-32686. PMID 11432848 DOI: 10.1074/jbc.M009975200 |
0.401 |
|
| 2001 |
Yang Q, Hewett TE, Klevitsky R, Sanbe A, Wang X, Robbins J. PKA-dependent phosphorylation of cardiac myosin binding protein C in transgenic mice. Cardiovascular Research. 51: 80-8. PMID 11399250 DOI: 10.1016/S0008-6363(01)00273-5 |
0.4 |
|
| 2001 |
Wang X, Osinska H, Dorn GW, Nieman M, Lorenz JN, Gerdes AM, Witt S, Kimball T, Gulick J, Robbins J. Mouse model of desmin-related cardiomyopathy. Circulation. 103: 2402-7. PMID 11352891 DOI: 10.1161/01.Cir.103.19.2402 |
0.352 |
|
| 2001 |
Sze RW, Chan CB, Dardzinski BJ, Dunn S, Sanbe A, Schmithorst V, Robbins J, Holland SK, Strife JL. Three-dimensional MR microscopy of a transgenic mouse model of dilated cardiomyopathy Pediatric Radiology. 31: 55-61. PMID 11214686 DOI: 10.1007/S002470000365 |
0.377 |
|
| 2001 |
Dalloz F, Osinska H, Robbins J. Manipulating the contractile apparatus: genetically defined animal models of cardiovascular disease. Journal of Molecular and Cellular Cardiology. 33: 9-25. PMID 11133219 DOI: 10.1006/Jmcc.2000.1289 |
0.418 |
|
| 2001 |
Schwartzbauer G, Robbins J. Matters of sex: sex matters. Circulation. 104: 1333-1335. DOI: 10.1161/Circ.104.12.1333 |
0.326 |
|
| 2000 |
James J, Zhang Y, Osinska H, Sanbe A, Klevitsky R, Hewett TE, Robbins J. Transgenic modeling of a cardiac troponin I mutation linked to familial hypertrophic cardiomyopathy. Circulation Research. 87: 805-11. PMID 11055985 DOI: 10.1161/01.Res.87.9.805 |
0.433 |
|
| 2000 |
Sanbe A, Gulick J, Hayes E, Warshaw D, Osinska H, Chan C, Klevitsky R, Robbins J. Myosin light chain replacement in the heart. American Journal of Physiology-Heart and Circulatory Physiology. 279. PMID 10993803 DOI: 10.1152/Ajpheart.2000.279.3.H1355 |
0.365 |
|
| 2000 |
Robbins J, Dorn GW. Listening for hoof beats in heart beats. Nature Medicine. 6: 968-70. PMID 10973308 DOI: 10.1038/79652 |
0.41 |
|
| 2000 |
Mochly-Rosen D, Wu G, Hahn H, Osinska H, Liron T, Lorenz JN, Yatani A, Robbins J, Dorn GW. Cardiotrophic effects of protein kinase C epsilon: analysis by in vivo modulation of PKCepsilon translocation. Circulation Research. 86: 1173-9. PMID 10850970 DOI: 10.1161/01.Res.86.11.1173 |
0.443 |
|
| 2000 |
Robbins J. Remodeling the cardiac sarcomere using transgenesis Annual Review of Physiology. 62: 261-287. PMID 10845092 DOI: 10.1146/annurev.physiol.62.1.261 |
0.436 |
|
| 2000 |
Nelson DP, Setser E, Hall DG, Schwartz SM, Hewitt T, Klevitsky R, Osinska H, Bellgrau D, Duke RC, Robbins J. Proinflammatory consequences of transgenic fas ligand expression in the heart. The Journal of Clinical Investigation. 105: 1199-208. PMID 10791994 DOI: 10.1172/JCI8212 |
0.39 |
|
| 2000 |
James J, Sanbe A, Yager K, Martin L, Klevitsky R, Robbins J. Genetic Manipulation of the Rabbit Heart via Transgenesis Circulation. 101: 1715-1721. PMID 10758055 DOI: 10.1161/01.Cir.101.14.1715 |
0.466 |
|
| 2000 |
Tardiff JC, Hewett TE, Factor SM, Vikstrom KL, Robbins J, Leinwand LA. Expression of the β (slow)-isoform of MHC in the adult mouse heart causes dominant-negative functional effects American Journal of Physiology - Heart and Circulatory Physiology. 278. PMID 10666070 DOI: 10.1152/Ajpheart.2000.278.2.H412 |
0.443 |
|
| 1999 |
Yang Q, Sanbe A, Osinska H, Hewett TE, Klevitsky R, Robbins J. In vivo modeling of myosin binding protein C familial hypertrophic cardiomyopathy. Circulation Research. 85: 841-7. PMID 10532952 DOI: 10.1161/01.Res.85.9.841 |
0.394 |
|
| 1999 |
Tardiff JC, Hewett TE, Palmer BM, Olsson C, Factor SM, Moore RL, Robbins J, Leinwand LA. Cardiac troponin T mutations result in allele-specific phenotypes in a mouse model for hypertrophic cardiomyopathy. The Journal of Clinical Investigation. 104: 469-81. PMID 10449439 DOI: 10.1172/Jci6067 |
0.46 |
|
| 1999 |
Sanbe A, Fewell JG, Gulick J, Osinska H, Lorenz J, Hall DG, Murray LA, Kimball TR, Witt SA, Robbins J. Abnormal cardiac structure and function in mice expressing nonphosphorylatable cardiac regulatory myosin light chain 2 Journal of Biological Chemistry. 274: 21085-21094. PMID 10409661 DOI: 10.1074/jbc.274.30.21085 |
0.342 |
|
| 1999 |
James J, Osinska H, Hewett TE, Kimball T, Klevitsky R, Witt S, Hall DG, Gulick J, Robbins J. Transgenic over-expression of a motor protein at high levels results in severe cardiac pathology. Transgenic Research. 8: 9-22. PMID 10399364 DOI: 10.1023/A:1008894507995 |
0.431 |
|
| 1999 |
Buck SH, Konyn PJ, Palermo J, Robbins J, Moss RL. Altered kinetics of contraction of mouse atrial myocytes expressing ventricular myosin regulatory light chain American Journal of Physiology-Heart and Circulatory Physiology. 276. PMID 10199839 DOI: 10.1152/Ajpheart.1999.276.4.H1167 |
0.374 |
|
| 1999 |
James J, Zhang S, Osinska H, Sambe A, Robbins J. Transgenic overexpression of a mutation in marine cardiac troponin I results in cardiac hypertrophy and early lethality Journal of Cardiac Failure. 5: 21. DOI: 10.1016/S1071-9164(99)91419-7 |
0.415 |
|
| 1998 |
Yang Q, Sanbe A, Osinska H, Hewett TE, Klevitsky R, Robbins J. A mouse model of myosin binding protein C human familial hypertrophic cardiomyopathy. The Journal of Clinical Investigation. 102: 1292-300. PMID 9769321 DOI: 10.1172/Jci3880 |
0.42 |
|
| 1998 |
Sussman MA, Lim HW, Gude N, Taigen T, Olson EN, Robbins J, Colbert MC, Gualberto A, Wieczorek DF, Molkentin JD. Prevention of cardiac hypertrophy in mice by calcineurin inhibition. Science (New York, N.Y.). 281: 1690-3. PMID 9733519 DOI: 10.1126/Science.281.5383.1690 |
0.432 |
|
| 1998 |
Tardiff JC, Factor SM, Tompkins BD, Hewett TE, Palmer BM, Moore RL, Schwartz S, Robbins J, Leinwand LA. A truncated cardiac troponin T molecule in transgenic mice suggests multiple cellular mechanisms for familial hypertrophic cardiomyopathy. The Journal of Clinical Investigation. 101: 2800-11. PMID 9637714 DOI: 10.1172/Jci2389 |
0.368 |
|
| 1998 |
Fewell JG, Hewett TE, Sanbe A, Klevitsky R, Hayes E, Warshaw D, Maughan D, Robbins J. Functional significance of cardiac myosin essential light chain isoform switching in transgenic mice Journal of Clinical Investigation. 101: 2630-2639. PMID 9637696 DOI: 10.1172/Jci2825 |
0.47 |
|
| 1998 |
Molkentin JD, Lu JR, Antos CL, Markham B, Richardson J, Robbins J, Grant SR, Olson EN. A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell. 93: 215-28. PMID 9568714 DOI: 10.1016/S0092-8674(00)81573-1 |
0.454 |
|
| 1998 |
James JF, Hewett TE, Robbins J. Cardiac physiology in transgenic mice. Circulation Research. 82: 407-15. PMID 9506700 DOI: 10.1161/01.Res.82.4.407 |
0.441 |
|
| 1998 |
Robbins J. α-Tropomyosin knockouts: A blow against transcriptional chauvinism Circulation Research. 82: 134-136. PMID 9440713 DOI: 10.1161/01.Res.82.1.134 |
0.377 |
|
| 1997 |
James J, Robbins J. Molecular remodeling of cardiac contractile function. American Journal of Physiology. Heart and Circulatory Physiology. 273: H2105-H2118. PMID 29586457 DOI: 10.1152/ajpheart.1997.273.5.H2105 |
0.399 |
|
| 1997 |
Colbert MC, Hall DG, Kimball TR, Witt SA, Lorenz JN, Kirby ML, Hewett TE, Klevitsky R, Robbins J. Cardiac compartment-specific overexpression of a modified retinoic acid receptor produces dilated cardiomyopathy and congestive heart failure in transgenic mice. The Journal of Clinical Investigation. 100: 1958-68. PMID 9329959 DOI: 10.1172/Jci119727 |
0.457 |
|
| 1997 |
Gulick J, Hewett TE, Klevitsky R, Buck SH, Moss RL, Robbins J. Transgenic remodeling of the regulatory myosin light chains in the mammalian heart. Circulation Research. 80: 655-64. PMID 9130446 DOI: 10.1161/01.Res.80.5.655 |
0.337 |
|
| 1997 |
Kumar A, Crawford K, Close L, Madison M, Lorenz J, Doetschman T, Pawlowski S, Duffy J, Neumann J, Robbins J, Boivin GP, O’Toole BA, Lessard JL. Rescue of cardiac α-actin-deficient mice by enteric smooth muscle γ-actin Proceedings of the National Academy of Sciences of the United States of America. 94: 4406-4411. PMID 9114002 DOI: 10.1073/Pnas.94.9.4406 |
0.407 |
|
| 1997 |
Lorenz JN, Robbins J. Measurement of intraventricular pressure and cardiac performance in the intact closed-chest anesthetized mouse. American Journal of Physiology-Heart and Circulatory Physiology. 272. PMID 9087586 DOI: 10.1152/Ajpheart.1997.272.3.H1137 |
0.39 |
|
| 1997 |
Ng WA, Doetschman T, Robbins J, Lessard JL. Muscle Isoactin Expression during in Vitro Differentiation of Murine Embryonic Stem Cells Pediatric Research. 41: 285-292. PMID 9029652 DOI: 10.1203/00006450-199702000-00021 |
0.303 |
|
| 1997 |
Robbins J. Altering cardiac function via transgenesis a nuts and bolts approach Trends in Cardiovascular Medicine. 7: 185-191. DOI: 10.1016/S1050-1738(97)00048-0 |
0.452 |
|
| 1996 |
Jones WK, Grupp IL, Doetschman T, Grupp G, Osinska H, Hewett TE, Boivin G, Gulick J, Ng WA, Robbins J. Ablation of the murine alpha myosin heavy chain gene leads to dosage effects and functional deficits in the heart. The Journal of Clinical Investigation. 98: 1906-17. PMID 8878443 DOI: 10.1172/Jci118992 |
0.384 |
|
| 1996 |
Knotts S, Sánchez A, Rindt H, Robbins J. Developmental modulation of a β myosin heavy chain promoter-driven transgene Developmental Dynamics. 206: 182-192. PMID 8725285 DOI: 10.1002/(Sici)1097-0177(199606)206:2<182::Aid-Aja7>3.0.Co;2-E |
0.367 |
|
| 1996 |
Palermo J, Gulick J, Colbert M, Fewell J, Robbins J. Transgenic remodeling of the contractile apparatus in the mammalian heart. Circulation Research. 78: 504-9. PMID 8593710 DOI: 10.1161/01.Res.78.3.504 |
0.449 |
|
| 1996 |
Burgess ML, Esser K, Robbins J, Kranias E, Tsika R, Gore M. REGULATION OF MUSCLE PROTEIN IN TRANSGENIC ANIMALS 164 Medicine &Amp Science in Sports &Amp Exercise. 28: 28. DOI: 10.1097/00005768-199605001-00164 |
0.304 |
|
| 1996 |
Robbins J. Regulation of cardiac gene expression during development. Cardiovascular Research. 31. DOI: 10.1016/S0008-6363(95)00081-X |
0.406 |
|
| 1995 |
Rindt H, Knotts S, Robbins J. Segregation of cardiac and skeletal muscle-specific regulatory elements of the beta-myosin heavy chain gene. Proceedings of the National Academy of Sciences of the United States of America. 92: 1540-1544. PMID 7878016 DOI: 10.1073/Pnas.92.5.1540 |
0.359 |
|
| 1995 |
Robbins J, Palermo J, Rindt H. In vivo definition of a cardiac specific promoter and its potential utility in remodeling the heart. Annals of the New York Academy of Sciences. 752: 492-505. PMID 7755294 DOI: 10.1111/J.1749-6632.1995.Tb17458.X |
0.43 |
|
| 1995 |
Knotts S, Rindt H, Robbins J. Position independent expression and developmental regulation is directed by the beta myosin heavy chain gene's 5' upstream region in transgenic mice. Nucleic Acids Research. 23: 3301-3309. PMID 7667107 DOI: 10.1093/Nar/23.16.3301 |
0.358 |
|
| 1994 |
Hewett TE, Grupp IL, Grupp G, Robbins J. Alpha-skeletal actin is associated with increased contractility in the mouse heart. Circulation Research. 74: 740-6. PMID 8137509 DOI: 10.1161/01.Res.74.4.740 |
0.407 |
|
| 1994 |
Jones WK, Sánchez A, Robbins J. Murine pulmonary myocardium: Developmental analysis of cardiac gene expression Developmental Dynamics. 200: 117-128. PMID 7919499 DOI: 10.1002/Aja.1002000204 |
0.344 |
|
| 1993 |
Robbins J. Gene targeting: The precise manipulation of the mammalian genome Circulation Research. 73: 3-9. PMID 8508532 DOI: 10.1161/01.Res.73.1.3 |
0.348 |
|
| 1993 |
Rindt H, Bauer BJ, Robbins J. In vitro production of enzymatically active myosin heavy chain. Journal of Muscle Research and Cell Motility. 14: 26-34. PMID 8478425 DOI: 10.1007/Bf00132177 |
0.313 |
|
| 1993 |
Grupp IL, Subramaniam A, Hewett TE, Robbins J, Grupp G. Comparison of normal, hypodynamic, and hyperdynamic mouse hearts using isolated work-performing heart preparations. The American Journal of Physiology. 265: H1401-10. PMID 7694487 DOI: 10.1152/Ajpheart.1993.265.4.H1401 |
0.304 |
|
| 1993 |
Robbins J. Recombinant DNA and gene isolation Trends in Cardiovascular Medicine. 3: 39-43. DOI: 10.1016/1050-1738(93)90034-4 |
0.336 |
|
| 1991 |
Ng WA, Grupp IL, Subramaniam A, Robbins J. Cardiac myosin heavy chain mRNA expression and myocardial function in the mouse heart Circulation Research. 68: 1742-1750. PMID 2036722 DOI: 10.1161/01.Res.68.6.1742 |
0.443 |
|
| 1991 |
McAuliffe JJ, Robbins J. Troponin T Expression in Normal and Pressure-Loaded Fetal Sheep Heart Pediatric Research. 29: 580-585. PMID 1866215 DOI: 10.1203/00006450-199106010-00012 |
0.416 |
|
| 1991 |
Ng W, Grupp I, Robbins J. Developmental expression of cardiac myosin and indices of myocardial function in murine heart Journal of Molecular and Cellular Cardiology. 23. DOI: 10.1016/0022-2828(91)91491-9 |
0.449 |
|
| 1991 |
Walsh RA, Henkel R, Robbins J. Cardiac myosin heavy and light chain gene expression in hypertrophy and heart failure Journal of Molecular and Cellular Cardiology. 23. DOI: 10.1016/0022-2828(91)91376-3 |
0.415 |
|
| 1978 |
Robbins J, Heywood SM. Quantification of myosin heavy-chain mRNA during myogenesis. European Journal of Biochemistry / Febs. 82: 601-8. PMID 564267 DOI: 10.1111/J.1432-1033.1978.Tb12056.X |
0.614 |
|
| 1976 |
Robbins J, Heywood SM. Preparation and characterization of myosin copy DNA. Biochemical and Biophysical Research Communications. 68: 918-26. PMID 56938 DOI: 10.1016/0006-291X(76)91233-X |
0.614 |
|
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