Kathleen M. Caron - Publications

Affiliations: 
Genetics & Molecular Biology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Genetics, Physiology Biology

73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Tutzauer J, Serafin DS, Schmidt T, Olde B, Caron KM, Leeb-Lundberg LMF. G protein-coupled estrogen receptor (GPER)/GPR30 forms a complex with the β-adrenergic receptor, a membrane-associated guanylate kinase (MAGUK) scaffold protein, and protein kinase A anchoring protein (AKAP) 5 in MCF7 breast cancer cells. Archives of Biochemistry and Biophysics. 752: 109882. PMID 38211639 DOI: 10.1016/j.abb.2024.109882  0.331
2023 Bálint L, Nelson-Maney NP, Tian Y, Serafin SD, Caron KM. Clinical Potential of Adrenomedullin Signaling in the Cardiovascular System. Circulation Research. 132: 1185-1202. PMID 37104556 DOI: 10.1161/CIRCRESAHA.123.321673  0.317
2022 Xu W, Nelson-Maney NP, Bálint L, Kwon HB, Davis RB, Dy DCM, Dunleavey JM, St Croix B, Caron KM. Orphan G-Protein Coupled Receptor GPRC5B Is Critical for Lymphatic Development. International Journal of Molecular Sciences. 23. PMID 35628521 DOI: 10.3390/ijms23105712  0.52
2022 Pacharne S, Livesey M, Kadmiel M, Wang N, Caron KM, Richards GO, Skerry TM. Accelerated Development With Increased Bone Mass and Skeletal Response to Loading Suggest Receptor Activity Modifying Protein-3 as a Bone Anabolic Target. Frontiers in Endocrinology. 12: 807882. PMID 35095771 DOI: 10.3389/fendo.2021.807882  0.77
2020 Kwon HB, Mackie DI, Bonnavion R, Mercier AL, Helker CSM, Son T, Guenter S, Serafin DS, Kim KW, Offermanns S, Caron KM, Stainier DYR. The Orphan G-Protein Coupled Receptor 182 Is a Negative Regulator of Definitive Hematopoiesis through Leukotriene B4 Signaling. Acs Pharmacology & Translational Science. 3: 676-689. PMID 32832870 DOI: 10.1021/acsptsci.0c00020  0.416
2020 Quinn KE, Matson BC, Caron KM. Deletion of atypical chemokine receptor 3 (ACKR3) increases immune cells at the fetal-maternal interface. Placenta. 95: 18-25. PMID 32452398 DOI: 10.1016/J.Placenta.2020.04.007  0.475
2020 Pawlak JB, Caron KM. Lymphatic Programing and Specialization in Hybrid Vessels. Frontiers in Physiology. 11: 114. PMID 32153423 DOI: 10.3389/Fphys.2020.00114  0.368
2020 Serafin DS, Harris NR, Nielsen NR, Mackie DI, Caron KM. Dawn of a New RAMPage. Trends in Pharmacological Sciences. PMID 32115276 DOI: 10.1016/J.Tips.2020.01.009  0.432
2020 Menon RT, Shrestha AK, Reynolds CL, Barrios R, Caron KM, Shivanna B. Adrenomedullin Is Necessary to Resolve Hyperoxia-Induced Experimental Bronchopulmonary Dysplasia and Pulmonary Hypertension in Mice. The American Journal of Pathology. PMID 32093901 DOI: 10.1016/J.Ajpath.2019.11.011  0.443
2020 Davis RB, Pahl K, Datto NC, Smith SV, Shawber C, Caron KM, Blatt J. Author Correction: Notch signaling pathway is a potential therapeutic target for extracranial vascular malformations. Scientific Reports. 10: 1847. PMID 31996757 DOI: 10.1038/S41598-020-58751-8  0.348
2019 Davis RB, Ding S, Nielsen NR, Pawlak JB, Blakeney ES, Caron KM. Calcitonin-Receptor-Like Receptor Signaling Governs Intestinal Lymphatic Innervation and Lipid Uptake. Acs Pharmacology & Translational Science. 2: 114-121. PMID 32219216 DOI: 10.1021/acsptsci.8b00061  0.432
2019 Quinn KE, Matson BC, Wetendorf M, Caron KM. Pinopodes: Recent advancements, current perspectives, and future directions. Molecular and Cellular Endocrinology. 501: 110644. PMID 31738970 DOI: 10.1016/J.Mce.2019.110644  0.31
2019 Mackie DI, Nielsen NR, Harris M, Singh S, Davis RB, Dy D, Ladds G, Caron KM. RAMP3 determines rapid recycling of atypical chemokine receptor-3 for guided angiogenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 31712427 DOI: 10.1073/Pnas.1905561116  0.532
2019 Wetendorf M, Randall LT, Lemma MT, Hurr SH, Pawlak JB, Tarran R, Doerschuk CM, Caron KM. E-Cigarette Exposure Delays Implantation and Causes Reduced Weight Gain in Female Offspring Exposed . Journal of the Endocrine Society. 3: 1907-1916. PMID 31598571 DOI: 10.1210/Js.2019-00216  0.303
2019 Pawlak JB, Bálint L, Lim L, Ma W, Davis RB, Benyo Z, Soares MJ, Oliver G, Kahn ML, Jakus Z, Caron KM. Lymphatic mimicry in maternal endothelial cells promotes placental spiral artery remodeling. The Journal of Clinical Investigation. PMID 31415243 DOI: 10.1172/Jci120446  0.462
2018 Davis RB, Pahl K, Datto NC, Smith SV, Shawber C, Caron KM, Blatt J. Notch signaling pathway is a potential therapeutic target for extracranial vascular malformations. Scientific Reports. 8: 17987. PMID 30573741 DOI: 10.1038/S41598-018-36628-1  0.38
2018 Matson BC, Li M, Trincot CE, Blakeney ES, Pierce SL, Caron KM. Genetic loss of proadrenomedullin N-terminal 20 peptide (PAMP) in mice is compatible with survival. Peptides. PMID 30537525 DOI: 10.1016/J.Peptides.2018.11.005  0.4
2018 Xu W, Wittchen ES, Hoopes SL, Stefanini L, Burridge K, Caron KM. Small GTPase Rap1A/B Is Required for Lymphatic Development and Adrenomedullin-Induced Stabilization of Lymphatic Endothelial Junctions. Arteriosclerosis, Thrombosis, and Vascular Biology. 38: 2410-2422. PMID 30354217 DOI: 10.1161/Atvbaha.118.311645  0.789
2018 Stefanini L, Lee RH, Paul DS, O'Shaughnessy EC, Ghalloussi D, Jones CI, Boulaftali Y, Poe KO, Piatt R, Kechele DO, Caron KM, Hahn KM, Gibbins JM, Bergmeier W. Functional redundancy between RAP1 isoforms in murine platelet production and function. Blood. PMID 30131434 DOI: 10.1182/Blood-2018-03-838714  0.313
2018 Mackie DI, Al Mutairi F, Davis RB, Kechele DO, Nielsen NR, Snyder JC, Caron MG, Kliman HJ, Berg JS, Simms J, Poyner DR, Caron KM. h mutation causes autosomal recessive nonimmune hydrops fetalis with lymphatic dysplasia. The Journal of Experimental Medicine. PMID 30115739 DOI: 10.1084/Jem.20180528  0.558
2018 Quinn KE, Mackie DI, Caron KM. Emerging roles of atypical chemokine receptor 3 (ACKR3) in normal development and physiology. Cytokine. 109: 17-23. PMID 29903572 DOI: 10.1016/J.Cyto.2018.02.024  0.541
2017 Kadmiel M, Matson BC, Espenschied ST, Lenhart PM, Caron KM. Loss of receptor activity-modifying protein 2 in mice causes placental dysfunction and alters PTH1R regulation. Plos One. 12: e0181597. PMID 28727763 DOI: 10.1371/Journal.Pone.0181597  0.832
2017 Davis RB, Kechele DO, Blakeney ES, Pawlak JB, Caron KM. Lymphatic deletion of calcitonin receptor-like receptor exacerbates intestinal inflammation. Jci Insight. 2: e92465. PMID 28352669 DOI: 10.1172/Jci.Insight.92465  0.489
2017 Kechele DO, Blue RE, Zwarycz B, Espenschied ST, Mah AT, Siegel MB, Perou CM, Ding S, Magness ST, Lund PK, Caron KM. Orphan Gpr182 suppresses ERK-mediated intestinal proliferation during regeneration and adenoma formation. The Journal of Clinical Investigation. PMID 28094771 DOI: 10.1172/Jci87588  0.381
2017 Young S, Hoff H, Matson B, Fitz V, Yuan L, Mathyk B, Lessey B, Caron K. Endometriosis reduces granulocyte colony stimulating factor receptor (GCSFR) expression: a mechanism reducing GCSF-mediated stromal adrenomedulin expression Fertility and Sterility. 108: e82-e83. DOI: 10.1016/J.Fertnstert.2017.07.257  0.401
2016 Pawlak JB, Wetzel-Strong SE, Dunn MK, Caron KM. Cardiovascular effects of exogenous adrenomedullin and CGRP in Ramp and Calcrl deficient mice. Peptides. PMID 27940069 DOI: 10.1016/J.Peptides.2016.12.002  0.518
2016 Kechele DO, Dunworth WP, Trincot CE, Wetzel-Strong SE, Li M, Ma H, Liu J, Caron KM. Endothelial Restoration of Receptor Activity-Modifying Protein 2 Is Sufficient to Rescue Lethality, but Survivors Develop Dilated Cardiomyopathy. Hypertension. PMID 27402918 DOI: 10.1161/Hypertensionaha.116.07191  0.837
2016 Klein KR, Matson BC, Caron KM. The expanding repertoire of receptor activity modifying protein (RAMP) function. Critical Reviews in Biochemistry and Molecular Biology. 1-7. PMID 26740457 DOI: 10.3109/10409238.2015.1128875  0.406
2015 Wetzel-Strong SE, Li M, Espenschied ST, Caron KM. Cohort of estrogen-induced microRNAs regulate adrenomedullin expression. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00305.2014. PMID 26582637 DOI: 10.1152/Ajpregu.00305.2014  0.374
2015 Klein KR, Caron KM. Adrenomedullin in lymphangiogenesis: from development to disease. Cellular and Molecular Life Sciences : Cmls. PMID 25953627 DOI: 10.1007/s00018-015-1921-3  0.345
2015 Bautch VL, Caron KM. Blood and lymphatic vessel formation. Cold Spring Harbor Perspectives in Biology. 7: a008268. PMID 25731762 DOI: 10.1101/Cshperspect.A008268  0.345
2015 Stefanini L, Paul DS, Robledo RF, Chan ER, Getz TM, Campbell RA, Kechele DO, Casari C, Piatt R, Caron KM, Mackman N, Weyrich AS, Parrott MC, Boulaftali Y, Adams MD, et al. RASA3 is a critical inhibitor of RAP1-dependent platelet activation. The Journal of Clinical Investigation. 125: 1419-32. PMID 25705885 DOI: 10.1172/Jci77993  0.319
2014 Klein KR, Karpinich NO, Espenschied ST, Willcockson HH, Dunworth WP, Hoopes SL, Kushner EJ, Bautch VL, Caron KM. Decoy receptor CXCR7 modulates adrenomedullin-mediated cardiac and lymphatic vascular development. Developmental Cell. 30: 528-40. PMID 25203207 DOI: 10.1016/J.Devcel.2014.07.012  0.815
2014 Matson BC, Caron KM. Adrenomedullin and endocrine control of immune cells during pregnancy. Cellular & Molecular Immunology. 11: 456-9. PMID 25132453 DOI: 10.1038/Cmi.2014.71  0.346
2014 Karpinich NO, Caron KM. Schlemm's canal: more than meets the eye, lymphatics in disguise. The Journal of Clinical Investigation. 124: 3701-3. PMID 25061871 DOI: 10.1172/Jci77507  0.335
2014 Matson BC, Caron KM. Uterine natural killer cells as modulators of the maternal-fetal vasculature. The International Journal of Developmental Biology. 58: 199-204. PMID 25023686 DOI: 10.1387/Ijdb.140032Kc  0.324
2014 Li M, Wetzel-Strong SE, Hua X, Tilley SL, Oswald E, Krummel MF, Caron KM. Deficiency of RAMP1 attenuates antigen-induced airway hyperresponsiveness in mice. Plos One. 9: e102356. PMID 25010197 DOI: 10.1371/Journal.Pone.0102356  0.358
2014 Karpinich NO, Caron KM. Apelin signaling: new G protein-coupled receptor pathway in lymphatic vascular development. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 239-41. PMID 24431421 DOI: 10.1161/Atvbaha.113.302905  0.535
2014 Wetzel-Strong SE, Li M, Klein KR, Nishikimi T, Caron KM. Epicardial-derived adrenomedullin drives cardiac hyperplasia during embryogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 243: 243-56. PMID 24123312 DOI: 10.1002/Dvdy.24065  0.401
2014 Lenhart PM, Nguyen T, Wise A, Caron KM, Herring AH, Stuebe AM. Adrenomedullin signaling pathway polymorphisms and adverse pregnancy outcomes. American Journal of Perinatology. 31: 327-34. PMID 23797962 DOI: 10.1055/S-0033-1349345  0.327
2013 Lenhart PM, Broselid S, Barrick CJ, Leeb-Lundberg LM, Caron KM. G-protein-coupled receptor 30 interacts with receptor activity-modifying protein 3 and confers sex-dependent cardioprotection. Journal of Molecular Endocrinology. 51: 191-202. PMID 23674134 DOI: 10.1530/Jme-13-0021  0.426
2013 Li M, Schwerbrock NM, Lenhart PM, Fritz-Six KL, Kadmiel M, Christine KS, Kraus DM, Espenschied ST, Willcockson HH, Mack CP, Caron KM. Fetal-derived adrenomedullin mediates the innate immune milieu of the placenta. The Journal of Clinical Investigation. 123: 2408-20. PMID 23635772 DOI: 10.1172/Jci67039  0.766
2013 Karpinich NO, Kechele DO, Espenschied ST, Willcockson HH, Fedoriw Y, Caron KM. Adrenomedullin gene dosage correlates with tumor and lymph node lymphangiogenesis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 590-600. PMID 23099649 DOI: 10.1096/Fj.12-214080  0.338
2013 Wootten D, Lindmark H, Kadmiel M, Willcockson H, Caron KM, Barwell J, Drmota T, Poyner DR. Receptor activity modifying proteins (RAMPs) interact with the VPAC2 receptor and CRF1 receptors and modulate their function. British Journal of Pharmacology. 168: 822-34. PMID 22946657 DOI: 10.1111/j.1476-5381.2012.02202.x  0.79
2013 Pacharne S, Richards G, Wang N, Skerry T, Caron K. Role of receptor activity modifying proteins in skeletal regulation Bone Abstracts. DOI: 10.1530/Boneabs.1.Pp158  0.466
2012 Hoopes SL, Willcockson HH, Caron KM. Characteristics of multi-organ lymphangiectasia resulting from temporal deletion of calcitonin receptor-like receptor in adult mice. Plos One. 7: e45261. PMID 23028890 DOI: 10.1371/Journal.Pone.0045261  0.82
2012 Kadmiel M, Fritz-Six KL, Caron KM. Understanding RAMPs through genetically engineered mouse models. Advances in Experimental Medicine and Biology. 744: 49-60. PMID 22434107 DOI: 10.1007/978-1-4614-2364-5_5  0.817
2012 Lenhart PM, Caron KM. Adrenomedullin and pregnancy: perspectives from animal models to humans. Trends in Endocrinology and Metabolism: Tem. 23: 524-32. PMID 22425034 DOI: 10.1016/J.Tem.2012.02.007  0.322
2012 Barrick CJ, Lenhart PM, Dackor RT, Nagle E, Caron KM. Loss of receptor activity-modifying protein 3 exacerbates cardiac hypertrophy and transition to heart failure in a sex-dependent manner. Journal of Molecular and Cellular Cardiology. 52: 165-74. PMID 22100352 DOI: 10.1016/J.Yjmcc.2011.10.021  0.803
2011 Karpinich NO, Hoopes SL, Kechele DO, Lenhart PM, Caron KM. Adrenomedullin Function in Vascular Endothelial Cells: Insights from Genetic Mouse Models. Current Hypertension Reviews. 7: 228-239. PMID 22582036 DOI: 10.2174/157340211799304761  0.789
2011 Kadmiel M, Fritz-Six K, Pacharne S, Richards GO, Li M, Skerry TM, Caron KM. Research resource: Haploinsufficiency of receptor activity-modifying protein-2 (RAMP2) causes reduced fertility, hyperprolactinemia, skeletal abnormalities, and endocrine dysfunction in mice. Molecular Endocrinology (Baltimore, Md.). 25: 1244-53. PMID 21566080 DOI: 10.1210/Me.2010-0400  0.818
2011 Lenhart P, Li M, Schwerbrock N, Fritz-Six K, Kadmiel M, Caron K. Fetal Loss of Adrenomedullin Causes Maternal Vascular Pathology Typical of Preeclampsia. Biology of Reproduction. 85: 800-800. DOI: 10.1093/Biolreprod/85.S1.800  0.75
2010 Caron KM. Adrenomedullin Signaling at the Maternal-Fetal Interface. Biology of Reproduction. 83: 111-111. DOI: 10.1093/Biolreprod/83.S1.111  0.314
2010 Schwerbrock N, Lenhart T, Li M, Kadmiel M, Fritz-Six K, Krause D, Christine K, Mack C, Caron K. Fetal loss of adrenomedullin causes vascular pathology typical of preeclampsia Journal of Reproductive Immunology. 86: 102-103. DOI: 10.1016/J.Jri.2010.08.045  0.752
2010 Kadmiel M, Caron KM. Gene targeted mouse models of adrenomedullin signaling The Calcitonin Gene-Related Peptide Family: Form, Function and Future Perspectives. 87-95. DOI: 10.1007/978-90-481-2909-6_6  0.804
2009 Huby AC, Rastaldi MP, Caron K, Smithies O, Dussaule JC, Chatziantoniou C. Restoration of podocyte structure and improvement of chronic renal disease in transgenic mice overexpressing renin. Plos One. 4: e6721. PMID 19696925 DOI: 10.1371/Journal.Pone.0006721  0.333
2009 Dunworth WP, Caron KM. G protein-coupled receptors as potential drug targets for lymphangiogenesis and lymphatic vascular diseases. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 650-6. PMID 19265032 DOI: 10.1161/Atvbaha.109.185066  0.829
2008 Dunworth WP, Fritz-Six KL, Caron KM. Adrenomedullin stabilizes the lymphatic endothelial barrier in vitro and in vivo. Peptides. 29: 2243-9. PMID 18929609 DOI: 10.1016/J.Peptides.2008.09.009  0.782
2008 Li M, Wu Y, Caron KM. Haploinsufficiency for adrenomedullin reduces pinopodes and diminishes uterine receptivity in mice. Biology of Reproduction. 79: 1169-75. PMID 18716289 DOI: 10.1095/Biolreprod.108.069336  0.562
2008 Fritz-Six KL, Dunworth WP, Li M, Caron KM. Adrenomedullin signaling is necessary for murine lymphatic vascular development. The Journal of Clinical Investigation. 118: 40-50. PMID 18097475 DOI: 10.1172/Jci33302  0.825
2007 Dackor R, Caron K. Mice heterozygous for adrenomedullin exhibit a more extreme inflammatory response to endotoxin-induced septic shock. Peptides. 28: 2164-70. PMID 17889965 DOI: 10.1016/J.Peptides.2007.08.012  0.791
2007 Dackor R, Fritz-Six K, Smithies O, Caron K. Receptor activity-modifying proteins 2 and 3 have distinct physiological functions from embryogenesis to old age. The Journal of Biological Chemistry. 282: 18094-9. PMID 17470425 DOI: 10.1074/Jbc.M703544200  0.832
2007 Caron K, Hagaman J, Nishikimi T, Kim HS, Smithies O. Adrenomedullin gene expression differences in mice do not affect blood pressure but modulate hypertension-induced pathology in males. Proceedings of the National Academy of Sciences of the United States of America. 104: 3420-5. PMID 17360661 DOI: 10.1073/Pnas.0611365104  0.398
2007 Gibbons C, Dackor R, Dunworth W, Fritz-Six K, Caron KM. Receptor activity-modifying proteins: RAMPing up adrenomedullin signaling. Molecular Endocrinology (Baltimore, Md.). 21: 783-96. PMID 17053041 DOI: 10.1210/Me.2006-0156  0.79
2006 Li M, Yee D, Magnuson TR, Smithies O, Caron KM. Reduced maternal expression of adrenomedullin disrupts fertility, placentation, and fetal growth in mice. The Journal of Clinical Investigation. 116: 2653-62. PMID 16981008 DOI: 10.1172/Jci28462  0.396
2006 Dackor RT, Fritz-Six K, Dunworth WP, Gibbons CL, Smithies O, Caron KM. Hydrops fetalis, cardiovascular defects, and embryonic lethality in mice lacking the calcitonin receptor-like receptor gene. Molecular and Cellular Biology. 26: 2511-8. PMID 16537897 DOI: 10.1128/Mcb.26.7.2511-2518.2006  0.807
2005 Lee G, Makhanova N, Caron K, Lopez ML, Gomez RA, Smithies O, Kim HS. Homeostatic responses in the adrenal cortex to the absence of aldosterone in mice. Endocrinology. 146: 2650-6. PMID 15731365 DOI: 10.1210/En.2004-1102  0.359
2002 Caron KM, Smithies O. Multiple roles of adrenomedullin revealed by animal models. Microscopy Research and Technique. 57: 55-9. PMID 11921356 DOI: 10.1002/Jemt.10046  0.366
2001 Rapacciuolo A, Esposito G, Caron K, Mao L, Thomas SA, Rockman HA. Important role of endogenous norepinephrine and epinephrine in the development of in vivo pressure-overload cardiac hypertrophy. Journal of the American College of Cardiology. 38: 876-82. PMID 11527648 DOI: 10.1016/S0735-1097(01)01433-4  0.33
2001 Caron KM, Smithies O. Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene. Proceedings of the National Academy of Sciences of the United States of America. 98: 615-9. PMID 11149956 DOI: 10.1073/Pnas.98.2.615  0.428
2000 Hasegawa T, Zhao L, Caron KM, Majdic G, Suzuki T, Shizawa S, Sasano H, Parker KL. Developmental roles of the steroidogenic acute regulatory protein (StAR) as revealed by StAR knockout mice. Molecular Endocrinology (Baltimore, Md.). 14: 1462-71. PMID 10976923 DOI: 10.1210/Mend.14.9.0515  0.361
1998 Caron KM, Soo SC, Parker KL. Targeted disruption of StAR provides novel insights into congenital adrenal hyperplasia. Endocrine Research. 24: 827-34. PMID 9888583 DOI: 10.3109/07435809809032693  0.36
1997 Wong M, Ikeda Y, Luo X, Caron KM, Weber TJ, Swain A, Schimmer BP, Parker KL. Steroidogenic factor 1 plays multiple roles in endocrine development and function. Recent Progress in Hormone Research. 52: 167-82; discussion 1. PMID 9238852  0.349
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