Wei-Shou Hu - Publications

Chemical Engineering University of Minnesota, Twin Cities, Minneapolis, MN 
Cell Biology, Biochemistry, Chemical Engineering

126 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Le T, O'Brien C, Gupta U, Sousa G, Daoutidis P, Hu WS. An integrated platform for mucin-type o-glycosylation network generation and visualization. Biotechnology and Bioengineering. PMID 30739313 DOI: 10.1002/bit.26952  0.64
2018 Bandyopadhyay AA, O'Brien SA, Zhao L, Fu HY, Vishwanathan N, Hu WS. Recurring Genomic Structural Variation Leads to Clonal Instability and Loss of Productivity. Biotechnology and Bioengineering. PMID 30144379 DOI: 10.1002/bit.26823  0.88
2018 Gupta U, Le T, Hu WS, Bhan A, Daoutidis P. Automated Network Generation and Analysis of Biochemical Reaction Pathways Using RING. Metabolic Engineering. PMID 30031851 DOI: 10.1016/j.ymben.2018.07.009  0.64
2018 O'Brien SA, Lee K, Fu HY, Lee Z, Le TS, Stach CS, McCann MG, Zhang AQ, Smanski MJ, Somia NV, Hu WS. Single Copy Transgene Integration in a Transcriptionally Active Site for Recombinant Protein Synthesis. Biotechnology Journal. e1800226. PMID 30024101 DOI: 10.1002/biot.201800226  0.72
2018 Raju R, Chau D, Notelaers T, Myers CL, Verfaillie CM, Hu WS. In Vitro Pluripotent Stem Cell Differentiation to Hepatocyte Ceases Further Maturation at an Equivalent Stage of E15 in Mouse Embryonic Liver Development. Stem Cells and Development. PMID 29851366 DOI: 10.1089/scd.2017.0270  0.72
2017 Pei H, Fu HY, Hirai H, Cho DS, O'Brien TD, Dutton J, Verfaillie CM, Hu WS. Generation of induced pluripotent stem cells from Chinese hamster embryonic fibroblasts. Stem Cell Research. 21: 132-136. PMID 28677528 DOI: 10.1016/j.scr.2017.04.010  0.72
2017 Breuer RJ, Bandyopadhyay A, O'Brien SA, Barnes AMT, Hunter RC, Hu WS, Dunny GM. Stochasticity in the enterococcal sex pheromone response revealed by quantitative analysis of transcription in single cells. Plos Genetics. 13: e1006878. PMID 28671948 DOI: 10.1371/journal.pgen.1006878  0.56
2017 Yusufi FNK, Lakshmanan M, Ho YS, Loo BLW, Ariyaratne P, Yang Y, Ng SK, Tan TRM, Yeo HC, Lim HL, Ng SW, Hiu AP, Chow CP, Wan C, Chen S, ... ... Hu WS, et al. Mammalian Systems Biotechnology Reveals Global Cellular Adaptations in a Recombinant CHO Cell Line. Cell Systems. 4: 530-542.e6. PMID 28544881 DOI: 10.1016/j.cels.2017.04.009  0.72
2017 Chen Y, Bandyopadhyay A, Kozlowicz BK, Haemig HAH, Tai A, Hu WS, Dunny GM. Mechanisms of peptide sex pheromone regulation of conjugation in Enterococcus faecalis. Microbiologyopen. PMID 28523739 DOI: 10.1002/mbo3.492  0.56
2017 Vishwanathan N, Bandyopadhyay A, Fu HY, Johnson KC, Springer NM, Hu WS. A COMPARATIVE GENOMIC HYBRIDIZATION APPROACH TO STUDY GENE COPY NUMBER VARIATIONS AMONG CHINESE HAMSTER CELL LINES. Biotechnology and Bioengineering. PMID 28409824 DOI: 10.1002/bit.26311  0.88
2017 Zhao L, Fu HY, Raju R, Vishwanathan N, Hu WS. Unveiling gene trait relationship by cross-platform meta-analysis on Chinese hamster ovary cell transcriptome. Biotechnology and Bioengineering. PMID 28218403 DOI: 10.1002/bit.26272  0.88
2017 Bandyopadhyay AA, Khetan A, Malmberg LH, Zhou W, Hu WS. Advancement in bioprocess technology: parallels between microbial natural products and cell culture biologics. Journal of Industrial Microbiology & Biotechnology. PMID 28185098 DOI: 10.1007/s10295-017-1913-4  0.44
2016 Raju R, Chau D, Cho DS, Park Y, Verfaillie C, Hu WS. Cell Expansion During Directed Differentiation Of Stem Cells Toward The Hepatic Lineage. Stem Cells and Development. PMID 27806669 DOI: 10.1089/scd.2016.0119  0.72
2016 Vishwanathan N, Bandyopadhyay AA, Fu HY, Sharma M, Johnson KC, Mudge J, Ramaraj T, Onsongo G, Silverstein KA, Jacob NM, Le H, Karypis G, Hu WS. Augmenting Chinese hamster genome assembly by identifying regions of high confidence. Biotechnology Journal. PMID 27374913 DOI: 10.1002/biot.201500455  0.88
2016 Mulukutla BC, Yongky A, Le T, Mashek DG, Hu WS. Regulation of Glucose Metabolism - A Perspective From Cell Bioprocessing. Trends in Biotechnology. PMID 27265890 DOI: 10.1016/j.tibtech.2016.04.012  0.84
2016 Bandyopadhyay A, O'Brien S, Frank KL, Dunny GM, Hu WS. Antagonistic donor density effect conserved in multiple Enterococcal conjugative plasmids. Applied and Environmental Microbiology. PMID 27208137 DOI: 10.1128/AEM.00363-16  1
2015 Le H, Vishwanathan N, Jacob NM, Gadgil M, Hu WS. Cell line development for biomanufacturing processes: recent advances and an outlook. Biotechnology Letters. 37: 1553-64. PMID 25971160 DOI: 10.1007/s10529-015-1843-z  1
2015 Mulukutla BC, Yongky A, Grimm S, Daoutidis P, Hu WS. Multiplicity of steady states in glycolysis and shift of metabolic state in cultured mammalian cells. Plos One. 10: e0121561. PMID 25806512 DOI: 10.1371/journal.pone.0121561  1
2015 Yongky A, Lee J, Le T, Mulukutla BC, Daoutidis P, Hu WS. Mechanism for multiplicity of steady states with distinct cell concentration in continuous culture of mammalian cells. Biotechnology and Bioengineering. 112: 1437-45. PMID 25676211 DOI: 10.1002/bit.25566  1
2015 Vishwanathan N, Yongky A, Johnson KC, Fu HY, Jacob NM, Le H, Yusufi FN, Lee DY, Hu WS. Global insights into the Chinese hamster and CHO cell transcriptomes. Biotechnology and Bioengineering. 112: 965-76. PMID 25450749 DOI: 10.1002/bit.25513  1
2014 Vishwanathan N, Le H, Le T, Hu WS. Advancing biopharmaceutical process science through transcriptome analysis. Current Opinion in Biotechnology. 30: 113-9. PMID 25014889 DOI: 10.1016/j.copbio.2014.06.011  1
2014 Mulukutla BC, Yongky A, Daoutidis P, Hu WS. Bistability in glycolysis pathway as a physiological switch in energy metabolism. Plos One. 9: e98756. PMID 24911170 DOI: 10.1371/journal.pone.0098756  1
2014 Johnson KC, Yongky A, Vishwanathan N, Jacob NM, Jayapal KP, Goudar CT, Karypis G, Hu WS. Exploring the transcriptome space of a recombinant BHK cell line through next generation sequencing. Biotechnology and Bioengineering. 111: 770-81. PMID 24249083 DOI: 10.1002/bit.25135  1
2014 Vishwanathan N, Le H, Jacob NM, Tsao YS, Ng SW, Loo B, Liu Z, Kantardjieff A, Hu WS. Transcriptome dynamics of transgene amplification in Chinese hamster ovary cells. Biotechnology and Bioengineering. 111: 518-28. PMID 24108600 DOI: 10.1002/bit.25117  1
2014 Subramanian K, Owens DJ, Raju R, Firpo M, O'Brien TD, Verfaillie CM, Hu WS. Spheroid culture for enhanced differentiation of human embryonic stem cells to hepatocyte-like cells. Stem Cells and Development. 23: 124-31. PMID 24020366 DOI: 10.1089/scd.2013.0097  1
2013 Shu CC, Chatterjee A, Hu WS, Ramkrishna D. Role of intracellular stochasticity in biofilm growth. Insights from population balance modeling. Plos One. 8: e79196. PMID 24232571 DOI: 10.1371/journal.pone.0079196  1
2013 Raju R, Chau D, Verfaillie CM, Hu WS. The road to regenerative liver therapies: the triumphs, trials and tribulations. Biotechnology Advances. 31: 1085-93. PMID 24055818 DOI: 10.1016/j.biotechadv.2013.08.022  1
2013 Le H, Vishwanathan N, Kantardjieff A, Doo I, Srienc M, Zheng X, Somia N, Hu WS. Dynamic gene expression for metabolic engineering of mammalian cells in culture. Metabolic Engineering. 20: 212-20. PMID 24055788 DOI: 10.1016/j.ymben.2013.09.004  1
2013 Chatterjee A, Cook LC, Shu CC, Chen Y, Manias DA, Ramkrishna D, Dunny GM, Hu WS. Antagonistic self-sensing and mate-sensing signaling controls antibiotic-resistance transfer. Proceedings of the National Academy of Sciences of the United States of America. 110: 7086-90. PMID 23569272 DOI: 10.1073/pnas.1212256110  1
2013 Keng S, Lin ER. Bidding for Taiwanese hearts: The achievements and limitations of China’s strategy to engage Taiwan New Dynamics in Cross-Taiwan Strait Relations: How Far Can the Rapprochement Go?. 169-189. DOI: 10.4324/9780203068205  0.32
2012 Le H, Kabbur S, Pollastrini L, Sun Z, Mills K, Johnson K, Karypis G, Hu WS. Multivariate analysis of cell culture bioprocess data--lactate consumption as process indicator. Journal of Biotechnology. 162: 210-23. PMID 22974585 DOI: 10.1016/j.jbiotec.2012.08.021  0.88
2012 Clark DS, Blanch HW, Wang DI, Demain AL, Wandrey C, Hu WS, Schultz JS, Shuler ML, Hoare M, Lightfoot EN, Humphrey AE, Dordick JS, Asenjo JA. Elmer L. Gaden, Jr. Tribute. Biotechnology and Bioengineering. 109: 2417-21. PMID 22910882 DOI: 10.1002/bit.24610  1
2012 Lo Nigro A, Geraerts M, Notelaers T, Roobrouck VD, Muijtjens M, Eggermont K, Subramanian K, Ulloa-Montoya F, Park Y, Owens J, Burns TC, Low W, Sharma S, Sohni A, Crabbe A, ... ... Hu WS, et al. MAPC culture conditions support the derivation of cells with nascent hypoblast features from bone marrow and blastocysts. Journal of Molecular Cell Biology. 4: 423-6. PMID 22878264 DOI: 10.1093/jmcb/mjs046  1
2012 Shu CC, Chatterjee A, Hu WS, Ramkrishna D. MODELING OF GENE REGULATORY PROCESSES BY POPULATION MEDIATED SIGNALING. NEW APPLICATIONS OF POPULATION BALANCES. Chemical Engineering Science. 70: 188-199. PMID 22581980 DOI: 10.1016/j.ces.2011.07.062  0.56
2012 Mulukutla BC, Gramer M, Hu WS. On metabolic shift to lactate consumption in fed-batch culture of mammalian cells. Metabolic Engineering. 14: 138-49. PMID 22244936 DOI: 10.1016/j.ymben.2011.12.006  1
2012 Castro-Melchor M, Le H, Hu WS. Transcriptome data analysis for cell culture processes. Advances in Biochemical Engineering/Biotechnology. 127: 27-70. PMID 22194060 DOI: 10.1007/10_2011_116  1
2011 Szperalski B, Jung C, Shao Z, Kantardjieff A, Hu WS. LDH-C can be differentially expressed during fermentation of CHO cells. Bmc Proceedings. 5: P107. PMID 22373157 DOI: 10.1186/1753-6561-5-S8-P107  0.84
2011 Le H, Castro-Melchor M, Hakemeyer C, Jung C, Szperalski B, Karypis G, Hu WS. Discerning key parameters influencing high productivity and quality through recognition of patterns in process data. Bmc Proceedings. 5: P91. PMID 22373092 DOI: 10.1186/1753-6561-5-S8-P91  0.88
2011 Shu CC, Chatterjee A, Dunny G, Hu WS, Ramkrishna D. Bistability versus bimodal distributions in gene regulatory processes from population balance Plos Computational Biology. 7. PMID 21901083 DOI: 10.1371/journal.pcbi.1002140  1
2011 Cook L, Chatterjee A, Barnes A, Yarwood J, Hu WS, Dunny G. Biofilm growth alters regulation of conjugation by a bacterial pheromone. Molecular Microbiology. 81: 1499-510. PMID 21843206 DOI: 10.1111/j.1365-2958.2011.07786.x  1
2011 Chatterjee A, Drews L, Mehra S, Takano E, Kaznessis YN, Hu WS. Convergent transcription in the butyrolactone regulon in Streptomyces coelicolor confers a bistable genetic switch for antibiotic biosynthesis. Plos One. 6: e21974. PMID 21765930 DOI: 10.1371/journal.pone.0021974  1
2011 Sharma S, Raju R, Sui S, Hu WS. Stem cell culture engineering - process scale up and beyond. Biotechnology Journal. 6: 1317-29. PMID 21721127 DOI: 10.1002/biot.201000435  0.72
2011 Ruffing AM, Castro-Melchor M, Hu WS, Chen RR. Genome sequence of the curdlan-producing Agrobacterium sp. strain ATCC 31749. Journal of Bacteriology. 193: 4294-5. PMID 21685288 DOI: 10.1128/JB.05302-11  1
2011 Chatterjee A, Johnson CM, Shu CC, Kaznessis YN, Ramkrishna D, Dunny GM, Hu WS. Convergent transcription confers a bistable switch in Enterococcus faecalis conjugation Proceedings of the National Academy of Sciences of the United States of America. 108: 9721-9726. PMID 21606359 DOI: 10.1073/pnas.1101569108  1
2011 Subramanian K, Owens DJ, O'Brien TD, Verfaillie CM, Hu WS. Enhanced differentiation of adult bone marrow-derived stem cells to liver lineage in aggregate culture. Tissue Engineering. Part A. 17: 2331-41. PMID 21548835 DOI: 10.1089/ten.TEA.2010.0667  1
2011 D'Alia D, Eggle D, Nieselt K, Hu WS, Breitling R, Takano E. Deletion of the signalling molecule synthase ScbA has pleiotropic effects on secondary metabolite biosynthesis, morphological differentiation and primary metabolism in Streptomyces coelicolor A3(2). Microbial Biotechnology. 4: 239-51. PMID 21342469 DOI: 10.1111/j.1751-7915.2010.00232.x  0.6
2011 Johnson KC, Jacob NM, Nissom PM, Hackl M, Lee LH, Yap M, Hu WS. Conserved microRNAs in Chinese hamster ovary cell lines. Biotechnology and Bioengineering. 108: 475-80. PMID 20830683 DOI: 10.1002/bit.22940  1
2010 Deshpande R, Sharma S, Verfaillie CM, Hu WS, Myers CL. A scalable approach for discovering conserved active subnetworks across species. Plos Computational Biology. 6: e1001028. PMID 21170309 DOI: 10.1371/journal.pcbi.1001028  1
2010 Castro-Melchor M, Charaniya S, Karypis G, Takano E, Hu WS. Genome-wide inference of regulatory networks in Streptomyces coelicolor. Bmc Genomics. 11: 578. PMID 20955611 DOI: 10.1186/1471-2164-11-578  1
2010 Mulukutla BC, Khan S, Lange A, Hu WS. Glucose metabolism in mammalian cell culture: new insights for tweaking vintage pathways. Trends in Biotechnology. 28: 476-84. PMID 20691487 DOI: 10.1016/j.tibtech.2010.06.005  1
2010 Yee JC, Jacob NM, Jayapal KP, Kok YJ, Philp R, Griffin TJ, Hu WS. Global assessment of protein turnover in recombinant antibody producing myeloma cells. Journal of Biotechnology. 148: 182-93. PMID 20540971 DOI: 10.1016/j.jbiotec.2010.06.005  1
2010 Charaniya S, Le H, Rangwala H, Mills K, Johnson K, Karypis G, Hu WS. Mining manufacturing data for discovery of high productivity process characteristics. Journal of Biotechnology. 147: 186-97. PMID 20416347 DOI: 10.1016/j.jbiotec.2010.04.005  0.88
2010 Subramanian K, Geraerts M, Pauwelyn KA, Park Y, Owens DJ, Muijtjens M, Ulloa-Montoya F, Jiang Y, Verfaillie CM, Hu WS. Isolation procedure and characterization of multipotent adult progenitor cells from rat bone marrow. Methods in Molecular Biology (Clifton, N.J.). 636: 55-78. PMID 20336516 DOI: 10.1007/978-1-60761-691-7_4  1
2010 Jayapal KP, Sui S, Philp RJ, Kok YJ, Yap MG, Griffin TJ, Hu WS. Multitagging proteomic strategy to estimate protein turnover rates in dynamic systems. Journal of Proteome Research. 9: 2087-97. PMID 20184388 DOI: 10.1021/pr9007738  1
2010 Jacob NM, Kantardjieff A, Yusufi FN, Retzel EF, Mulukutla BC, Chuah SH, Yap M, Hu WS. Reaching the depth of the Chinese hamster ovary cell transcriptome. Biotechnology and Bioengineering. 105: 1002-9. PMID 19882695 DOI: 10.1002/bit.22588  1
2010 Kantardjieff A, Jacob NM, Yee JC, Epstein E, Kok YJ, Philp R, Betenbaugh M, Hu WS. Transcriptome and proteome analysis of Chinese hamster ovary cells under low temperature and butyrate treatment. Journal of Biotechnology. 145: 143-59. PMID 19770009 DOI: 10.1016/j.jbiotec.2009.09.008  1
2009 Kantardjieff A, Nissom PM, Chuah SH, Yusufi F, Jacob NM, Mulukutla BC, Yap M, Hu WS. Developing genomic platforms for Chinese hamster ovary cells. Biotechnology Advances. 27: 1028-35. PMID 19470403 DOI: 10.1016/j.biotechadv.2009.05.023  1
2009 Charaniya S, Karypis G, Hu WS. Mining transcriptome data for function-trait relationship of hyper productivity of recombinant antibody. Biotechnology and Bioengineering. 102: 1654-69. PMID 19132744 DOI: 10.1002/bit.22210  0.88
2009 Yee JC, Gerdtzen ZP, Hu WS. Comparative transcriptome analysis to unveil genes affecting recombinant protein productivity in mammalian cells. Biotechnology and Bioengineering. 102: 246-63. PMID 18726962 DOI: 10.1002/bit.22039  1
2008 Charaniya S, Hu WS, Karypis G. Mining bioprocess data: opportunities and challenges. Trends in Biotechnology. 26: 690-9. PMID 18977046 DOI: 10.1016/j.tibtech.2008.09.003  0.88
2008 Yee JC, Wlaschin KF, Chuah SH, Nissom PM, Hu WS. Quality assessment of cross-species hybridization of CHO transcriptome on a mouse DNA oligo microarray. Biotechnology and Bioengineering. 101: 1359-65. PMID 18814282 DOI: 10.1002/bit.21984  1
2008 Chatterjee A, Kaznessis YN, Hu WS. Tweaking biological switches through a better understanding of bistability behavior. Current Opinion in Biotechnology. 19: 475-81. PMID 18804166 DOI: 10.1016/j.copbio.2008.08.010  1
2008 Mehra S, Charaniya S, Takano E, Hu WS. A bistable gene switch for antibiotic biosynthesis: the butyrolactone regulon in Streptomyces coelicolor. Plos One. 3: e2724. PMID 18628968 DOI: 10.1371/journal.pone.0002724  1
2008 Cameron CM, Harding F, Hu WS, Kaufman DS. Activation of hypoxic response in human embryonic stem cell-derived embryoid bodies. Experimental Biology and Medicine (Maywood, N.J.). 233: 1044-57. PMID 18535160 DOI: 10.3181/0709-RM-263  1
2008 Jayapal KP, Philp RJ, Kok YJ, Yap MG, Sherman DH, Griffin TJ, Hu WS. Uncovering genes with divergent mRNA-protein dynamics in Streptomyces coelicolor. Plos One. 3: e2097. PMID 18461186 DOI: 10.1371/journal.pone.0002097  1
2008 Sahin MB, Schwartz RE, Buckley SM, Heremans Y, Chase L, Hu WS, Verfaillie CM. Isolation and characterization of a novel population of progenitor cells from unmanipulated rat liver. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. 14: 333-45. PMID 18306374 DOI: 10.1002/lt.21380  1
2008 Lian W, Jayapal KP, Charaniya S, Mehra S, Glod F, Kyung YS, Sherman DH, Hu WS. Genome-wide transcriptome analysis reveals that a pleiotropic antibiotic regulator, AfsS, modulates nutritional stress response in Streptomyces coelicolor A3(2). Bmc Genomics. 9: 56. PMID 18230178 DOI: 10.1186/1471-2164-9-56  1
2008 Yee JC, de Leon Gatti M, Philp RJ, Yap M, Hu WS. Genomic and proteomic exploration of CHO and hybridoma cells under sodium butyrate treatment. Biotechnology and Bioengineering. 99: 1186-204. PMID 17929327 DOI: 10.1002/bit.21665  0.84
2007 Seth G, Charaniya S, Wlaschin KF, Hu WS. In pursuit of a super producer-alternative paths to high producing recombinant mammalian cells. Current Opinion in Biotechnology. 18: 557-64. PMID 18082393 DOI: 10.1016/j.copbio.2007.10.012  1
2007 Charaniya S, Mehra S, Lian W, Jayapal KP, Karypis G, Hu WS. Transcriptome dynamics-based operon prediction and verification in Streptomyces coelicolor. Nucleic Acids Research. 35: 7222-36. PMID 17959654 DOI: 10.1093/nar/gkm501  1
2007 Hossler P, Mulukutla BC, Hu WS. Systems analysis of N-glycan processing in mammalian cells. Plos One. 2: e713. PMID 17684559 DOI: 10.1371/journal.pone.0000713  1
2007 Ulloa-Montoya F, Kidder BL, Pauwelyn KA, Chase LG, Luttun A, Crabbe A, Geraerts M, Sharov AA, Piao Y, Ko MS, Hu WS, Verfaillie CM. Comparative transcriptome analysis of embryonic and adult stem cells with extended and limited differentiation capacity. Genome Biology. 8: R163. PMID 17683608 DOI: 10.1186/gb-2007-8-8-r163  1
2007 Griffin TJ, Seth G, Xie H, Bandhakavi S, Hu WS. Advancing mammalian cell culture engineering using genome-scale technologies. Trends in Biotechnology. 25: 401-8. PMID 17681628 DOI: 10.1016/j.tibtech.2007.07.004  1
2007 Wlaschin KF, Hu WS. Engineering cell metabolism for high-density cell culture via manipulation of sugar transport. Journal of Biotechnology. 131: 168-76. PMID 17662499 DOI: 10.1016/j.jbiotec.2007.06.006  1
2007 Jayapal KP, Lian W, Glod F, Sherman DH, Hu WS. Comparative genomic hybridizations reveal absence of large Streptomyces coelicolor genomic islands in Streptomyces lividans. Bmc Genomics. 8: 229. PMID 17623098 DOI: 10.1186/1471-2164-8-229  1
2007 Wlaschin KF, Hu WS. A scaffold for the Chinese hamster genome. Biotechnology and Bioengineering. 98: 429-39. PMID 17390381 DOI: 10.1002/bit.21430  1
2007 De Leon Gatti M, Wlaschin KF, Nissom PM, Yap M, Hu WS. Comparative transcriptional analysis of mouse hybridoma and recombinant Chinese hamster ovary cells undergoing butyrate treatment. Journal of Bioscience and Bioengineering. 103: 82-91. PMID 17298905 DOI: 10.1263/jbb.103.82  1
2007 Seth G, Philp RJ, Lau A, Jiun KY, Yap M, Hu WS. Molecular portrait of high productivity in recombinant NS0 cells. Biotechnology and Bioengineering. 97: 933-51. PMID 17149768 DOI: 10.1002/bit.21234  1
2006 Wlaschin KF, Seth G, Hu WS. Toward genomic cell culture engineering. Cytotechnology. 50: 121-40. PMID 19003075 DOI: 10.1007/s10616-006-9004-9  1
2006 Nissom PM, Sanny A, Kok YJ, Hiang YT, Chuah SH, Shing TK, Lee YY, Wong KT, Hu WS, Sim MY, Philp R. Transcriptome and proteome profiling to understanding the biology of high productivity CHO cells. Molecular Biotechnology. 34: 125-40. PMID 17172658  0.84
2006 Seth G, Hossler P, Yee JC, Hu WS. Engineering cells for cell culture bioprocessing--physiological fundamentals. Advances in Biochemical Engineering/Biotechnology. 101: 119-64. PMID 16989260 DOI: 10.1007/10_017  1
2006 Wlaschin KF, Hu WS. Fedbatch culture and dynamic nutrient feeding. Advances in Biochemical Engineering/Biotechnology. 101: 43-74. PMID 16989257 DOI: 10.1007/10_015  1
2006 Nahmias Y, Schwartz RE, Hu WS, Verfaillie CM, Odde DJ. Endothelium-mediated hepatocyte recruitment in the establishment of liver-like tissue in vitro. Tissue Engineering. 12: 1627-38. PMID 16846358 DOI: 10.1089/ten.2006.12.1627  1
2006 Hossler P, Goh LT, Lee MM, Hu WS. GlycoVis: visualizing glycan distribution in the protein N-glycosylation pathway in mammalian cells. Biotechnology and Bioengineering. 95: 946-60. PMID 16807922 DOI: 10.1002/bit.21062  0.76
2006 Cameron CM, Hu WS, Kaufman DS. Improved development of human embryonic stem cell-derived embryoid bodies by stirred vessel cultivation. Biotechnology and Bioengineering. 94: 938-48. PMID 16547998 DOI: 10.1002/bit.20919  1
2006 Gadgil M, Mehra S, Kapur V, Hu WS. TimeView: for comparative gene expression analysis. Applied Bioinformatics. 5: 41-4. PMID 16539536 DOI: 10.2165/00822942-200605010-00005  1
2006 Mehra S, Lian W, Jayapal KP, Charaniya SP, Sherman DH, Hu WS. A framework to analyze multiple time series data: a case study with Streptomyces coelicolor. Journal of Industrial Microbiology & Biotechnology. 33: 159-72. PMID 16217633 DOI: 10.1007/s10295-005-0034-7  1
2006 Seth G, Ozturk M, Hu WS. Reverting cholesterol auxotrophy of NS0 cells by altering epigenetic gene silencing. Biotechnology and Bioengineering. 93: 820-7. PMID 16189819 DOI: 10.1002/bit.20720  1
2006 Seth G, McIvor RS, Hu WS. 17Beta-hydroxysteroid dehydrogenase type 7 (Hsd17b7) reverts cholesterol auxotrophy in NS0 cells. Journal of Biotechnology. 121: 241-52. PMID 16126295 DOI: 10.1016/j.jbiotec.2005.07.017  1
2005 Schwartz RE, Linehan JL, Painschab MS, Hu WS, Verfaillie CM, Kaufman DS. Defined conditions for development of functional hepatic cells from human embryonic stem cells. Stem Cells and Development. 14: 643-55. PMID 16433619 DOI: 10.1089/scd.2005.14.643  1
2005 Ulloa-Montoya F, Verfaillie CM, Hu WS. Culture systems for pluripotent stem cells. Journal of Bioscience and Bioengineering. 100: 12-27. PMID 16233846 DOI: 10.1263/jbb.100.12  1
2005 Wlaschin KF, Nissom PM, Gatti Mde L, Ong PF, Arleen S, Tan KS, Rink A, Cham B, Wong K, Yap M, Hu WS. EST sequencing for gene discovery in Chinese hamster ovary cells. Biotechnology and Bioengineering. 91: 592-606. PMID 16003777 DOI: 10.1002/bit.20511  1
2005 Mehra S, Hu WS. A kinetic model of quantitative real-time polymerase chain reaction. Biotechnology and Bioengineering. 91: 848-60. PMID 15986490 DOI: 10.1002/bit.20555  1
2005 Gadgil M, Kapur V, Hu WS. Transcriptional response of Escherichia coli to temperature shift. Biotechnology Progress. 21: 689-99. PMID 15932244 DOI: 10.1021/bp049630l  1
2005 Gadgil M, Lian W, Gadgil C, Kapur V, Hu WS. An analysis of the use of genomic DNA as a universal reference in two channel DNA microarrays. Bmc Genomics. 6: 66. PMID 15877823 DOI: 10.1186/1471-2164-6-66  1
2005 Abu-Absi SF, Hu WS, Hansen LK. Dexamethasone effects on rat hepatocyte spheroid formation and function. Tissue Engineering. 11: 415-26. PMID 15869420 DOI: 10.1089/ten.2005.11.415  1
2005 Abu-Absi SF, Seth G, Narayanan RA, Groehler K, Lai P, Anderson ML, Sielaff T, Hu WS. Characterization of a hollow fiber bioartificial liver device. Artificial Organs. 29: 419-22. PMID 15854219 DOI: 10.1111/j.1525-1594.2005.29070.x  1
2005 Seth G, Philp RJ, Denoya CD, McGrath K, Stutzman-Engwall KJ, Yap M, Hu WS. Large-scale gene expression analysis of cholesterol dependence in NS0 cells. Biotechnology and Bioengineering. 90: 552-67. PMID 15830340 DOI: 10.1002/bit.20429  1
2005 Adams DN, Kao EY, Hypolite CL, Distefano MD, Hu WS, Letourneau PC. Growth cones turn and migrate up an immobilized gradient of the laminin IKVAV peptide. Journal of Neurobiology. 62: 134-47. PMID 15452851 DOI: 10.1002/neu.20075  1
2004 Abu-Absi SF, Hansen LK, Hu WS. Three-dimensional co-culture of hepatocytes and stellate cells. Cytotechnology. 45: 125-40. PMID 19003250 DOI: 10.1007/s10616-004-7996-6  1
2004 Mehra S, Hu WS, Karypis G. A Boolean algorithm for reconstructing the structure of regulatory networks. Metabolic Engineering. 6: 326-39. PMID 15491862 DOI: 10.1016/j.ymben.2004.05.002  1
2004 Gadgil C, Yeckel A, Derby JJ, Hu WS. A diffusion-reaction model for DNA microarray assays. Journal of Biotechnology. 114: 31-45. PMID 15464596 DOI: 10.1016/j.jbiotec.2004.05.008  1
2004 Gerdtzen ZP, Daoutidis P, Hu WS. Non-linear reduction for kinetic models of metabolic reaction networks. Metabolic Engineering. 6: 140-54. PMID 15113567 DOI: 10.1016/j.ymben.2003.11.003  1
2004 Korke R, Gatti Mde L, Lau AL, Lim JW, Seow TK, Chung MC, Hu WS. Large scale gene expression profiling of metabolic shift of mammalian cells in culture. Journal of Biotechnology. 107: 1-17. PMID 14687967 DOI: 10.1016/j.jbiotec.2003.09.007  1
2003 Gambhir A, Korke R, Lee J, Fu PC, Europa A, Hu WS. Analysis of cellular metabolism of hybridoma cells at distinct physiological states. Journal of Bioscience and Bioengineering. 95: 317-27. PMID 16233414  0.76
2003 Lee YY, Yap MG, Hu WS, Wong KT. Low-glutamine fed-batch cultures of 293-HEK serum-free suspension cells for adenovirus production. Biotechnology Progress. 19: 501-9. PMID 12675594 DOI: 10.1021/bp025638o  0.44
2003 Namjoshi AA, Hu WS, Ramkrishna D. Unveiling steady-state multiplicity in hybridoma cultures: the cybernetic approach. Biotechnology and Bioengineering. 81: 80-91. PMID 12432584 DOI: 10.1002/bit.10447  1
2002 Gadgil C, Rink A, Beattie C, Hu WS. A mathematical model for suppression subtractive hybridization. Comparative and Functional Genomics. 3: 405-22. PMID 18629052 DOI: 10.1002/cfg.206  0.36
2002 Narayanan RA, Rink A, Beattie CW, Hu WS. Differential gene expression analysis during porcine hepatocyte spheroid formation. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 13: 515-23. PMID 12370782 DOI: 10.1007/s00335-002-2179-2  1
2002 Schwartz RE, Reyes M, Koodie L, Jiang Y, Blackstad M, Lund T, Lenvik T, Johnson S, Hu WS, Verfaillie CM. Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells. The Journal of Clinical Investigation. 109: 1291-302. PMID 12021244 DOI: 10.1172/JCI15182  1
2002 Tzanakakis ES, Waxman DJ, Hansen LK, Remmel RP, Hu WS. Long-term enhancement of cytochrome P450 2B1/2 expression in rat hepatocyte spheroids through adenovirus-mediated gene transfer. Cell Biology and Toxicology. 18: 13-27. PMID 11991083 DOI: 10.1023/A:1014415128392  1
2002 Abu-Absi SF, Friend JR, Hansen LK, Hu WS. Structural polarity and functional bile canaliculi in rat hepatocyte spheroids. Experimental Cell Research. 274: 56-67. PMID 11855857 DOI: 10.1006/excr.2001.5467  1
2002 Korke R, Rink A, Seow TK, Chung MC, Beattie CW, Hu WS. Genomic and proteomic perspectives in cell culture engineering. Journal of Biotechnology. 94: 73-92. PMID 11792453 DOI: 10.1016/S0168-1656(01)00420-5  1
2001 Tzanakakis ES, Hsiao CC, Matsushita T, Remmel RP, Hu WS. Probing enhanced cytochrome P450 2B1/2 activity in rat hepatocyte spheroids through confocal laser scanning microscopy. Cell Transplantation. 10: 329-42. PMID 11437078  1
2001 Tzanakakis ES, Hansen LK, Hu WS. The role of actin filaments and microtubules in hepatocyte spheroid self-assembly. Cell Motility and the Cytoskeleton. 48: 175-89. PMID 11223949 DOI: 10.1002/1097-0169(200103)48:3<175::AID-CM1007>3.0.CO;2-2  0.72
2000 Tzanakakis ES, Hess DJ, Sielaff TD, Hu WS. Extracorporeal tissue engineered liver-assist devices. Annual Review of Biomedical Engineering. 2: 607-32. PMID 11701525 DOI: 10.1146/annurev.bioeng.2.1.607  1
1999 Hansen LK, Friend JR, Remmel R, Cerra FB, Hu WS. Development of a bioartificial liver device. Methods in Molecular Medicine. 18: 423-31. PMID 21370193 DOI: 10.1385/0-89603-516-6:423  0.72
1999 Friend JR, Wu FJ, Hansen LK, Remmel RP, Hu WS. Formation and characterization of hepatocyte spheroids. Methods in Molecular Medicine. 18: 245-52. PMID 21370181 DOI: 10.1385/0-89603-516-6:245  0.72
1999 Wu FJ, Friend JR, Remmel RP, Cerra FB, Hu WS. Enhanced cytochrome P450 IA1 activity of self-assembled rat hepatocyte spheroids. Cell Transplantation. 8: 233-46. PMID 10442736  1
1997 Hu WS, Friend JR, Wu FJ, Sielaff T, Peshwa MV, Lazar A, Nyberg SL, Remmel RP, Cerra FB. Development of a bioartificial liver employing xenogeneic hepatocytes. Cytotechnology. 23: 29-38. PMID 22358518 DOI: 10.1023/A:1007906512616  1
1997 Herbert CB, McLernon TL, Hypolite CL, Adams DN, Pikus L, Huang CC, Fields GB, Letourneau PC, Distefano MD, Hu WS. Micropatterning gradients and controlling surface densities of photoactivatable biomolecules on self-assembled monolayers of oligo(ethylene glycol) alkanethiolates. Chemistry & Biology. 4: 731-7. PMID 9375251  1
1997 Hypolite CL, McLernon TL, Adams DN, Chapman KE, Herbert CB, Huang CC, Distefano MD, Hu WS. Formation of microscale gradients of protein using heterobifunctional photolinkers. Bioconjugate Chemistry. 8: 658-63. PMID 9327128 DOI: 10.1021/bc9701252  1
1996 Wu FJ, Friend JR, Lazar A, Mann HJ, Remmel RP, Cerra FB, Hu WS. Hollow fiber bioartificial liver utilizing collagen-entrapped porcine hepatocyte spheroids. Biotechnology and Bioengineering. 52: 34-44. PMID 18629850 DOI: 10.1002/(SICI)1097-0290(19961005)52:1<34::AID-BIT4>3.0.CO;2-#  1
1996 Wu FJ, Friend JR, Hsiao CC, Zilliox MJ, Ko WJ, Cerra FB, Hu WS. Efficient assembly of rat hepatocyte spheroids for tissue engineering applications. Biotechnology and Bioengineering. 50: 404-15. PMID 18626989 DOI: 10.1002/(SICI)1097-0290(19960520)50:4<404::AID-BIT7>3.0.CO;2-P  1
1988 Hu WS. Cell culture engineering Trends in Biotechnology. 6: 83-84.  1
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