Year |
Citation |
Score |
2023 |
Martinez-Cano D, Ravichandran R, Le H, Wong HE, Jagannathan B, Liu EJ, Bailey W, Yang J, Matthies K, Barkhordarian H, Shah B, Srinivasan N, Zhang J, Hsu A, Wypych J, et al. Process development of a SARS-CoV-2 nanoparticle vaccine. Process Biochemistry (Barking, London, England). 129: 241-256. PMID 37013198 DOI: 10.1016/j.procbio.2023.03.014 |
0.314 |
|
2021 |
Diep J, Le H, Le K, Zasadzinska E, Tat J, Yam P, Zastrow R, Gomez N, Stevens J. Microfluidic Chip-Based Single-Cell Cloning to Accelerate Biologic Production Timelines. Biotechnology Progress. PMID 34323013 DOI: 10.1002/btpr.3192 |
0.413 |
|
2019 |
Chen C, Le K, Le H, Daris K, Soice N, Stevens J, Goudar CT. Methods for Estimating the Probability of Clonality in Cell Line Development. Biotechnology Journal. e1900289. PMID 31841273 DOI: 10.1002/Biot.201900289 |
0.407 |
|
2019 |
Le K, Tan C, Le H, Tat J, Zasadzinska E, Diep J, Zastrow R, Chen C, Stevens J. Assuring Clonality on the Beacon Digital Cell Line Development Platform. Biotechnology Journal. e1900247. PMID 31743597 DOI: 10.1002/Biot.201900247 |
0.488 |
|
2017 |
Chen C, Le H, Follstad B, Goudar CT. A Comparative Transcriptomics Workflow for Analyzing Microarray Data From CHO Cell Cultures. Biotechnology Journal. PMID 29215210 DOI: 10.1002/Biot.201700228 |
0.531 |
|
2017 |
Munro TP, Le K, Le H, Zhang L, Stevens J, Soice N, Benchaar SA, Hong RW, Goudar CT. Accelerating Patient Access to Novel Biologics using Stable Pool-derived Product for Non-clinical Studies and Single Clone-derived Product for Clinical Studies. Biotechnology Progress. PMID 29055113 DOI: 10.1002/Btpr.2572 |
0.479 |
|
2017 |
Chen C, Le H, Goudar CT. Evaluation of two public genome references for Chinese hamster ovary cells in the context of RNA-seq based gene expression analysis. Biotechnology and Bioengineering. PMID 28295162 DOI: 10.1002/Bit.26290 |
0.491 |
|
2016 |
Vishwanathan N, Bandyopadhyay AA, Fu HY, Sharma M, Johnson KC, Mudge J, Ramaraj T, Onsongo G, Silverstein KA, Jacob NM, Le H, Karypis G, Hu WS. Augmenting Chinese hamster genome assembly by identifying regions of high confidence. Biotechnology Journal. PMID 27374913 DOI: 10.1002/Biot.201500455 |
0.754 |
|
2016 |
Chen C, Le H, Goudar CT. Integration of systems biology in cell line and process development for biopharmaceutical manufacturing Biochemical Engineering Journal. 107: 11-17. DOI: 10.1016/J.Bej.2015.11.013 |
0.521 |
|
2015 |
Chen C, Le H, Goudar CT. An automated RNA-Seq analysis pipeline to identify and visualize differentially expressed genes and pathways in CHO cells. Biotechnology Progress. PMID 26150012 DOI: 10.1002/Btpr.2137 |
0.475 |
|
2015 |
Le H, Chen C, Goudar CT. An evaluation of public genomic references for mapping RNA-Seq data from Chinese hamster ovary cells. Biotechnology and Bioengineering. PMID 26010986 DOI: 10.1002/Bit.25649 |
0.38 |
|
2015 |
Le H, Jerums M, Goudar CT. Characterization of intrinsic variability in time-series metabolomic data of cultured mammalian cells. Biotechnology and Bioengineering. PMID 25976859 DOI: 10.1002/Bit.25646 |
0.363 |
|
2015 |
Le H, Vishwanathan N, Jacob NM, Gadgil M, Hu WS. Cell line development for biomanufacturing processes: recent advances and an outlook. Biotechnology Letters. 37: 1553-64. PMID 25971160 DOI: 10.1007/S10529-015-1843-Z |
0.765 |
|
2015 |
Vishwanathan N, Yongky A, Johnson KC, Fu HY, Jacob NM, Le H, Yusufi FN, Lee DY, Hu WS. Global insights into the Chinese hamster and CHO cell transcriptomes. Biotechnology and Bioengineering. 112: 965-76. PMID 25450749 DOI: 10.1002/Bit.25513 |
0.736 |
|
2014 |
Vishwanathan N, Le H, Le T, Hu WS. Advancing biopharmaceutical process science through transcriptome analysis. Current Opinion in Biotechnology. 30: 113-9. PMID 25014889 DOI: 10.1016/J.Copbio.2014.06.011 |
0.787 |
|
2014 |
Vishwanathan N, Le H, Jacob NM, Tsao YS, Ng SW, Loo B, Liu Z, Kantardjieff A, Hu WS. Transcriptome dynamics of transgene amplification in Chinese hamster ovary cells. Biotechnology and Bioengineering. 111: 518-28. PMID 24108600 DOI: 10.1002/Bit.25117 |
0.74 |
|
2013 |
Le H, Vishwanathan N, Kantardjieff A, Doo I, Srienc M, Zheng X, Somia N, Hu WS. Dynamic gene expression for metabolic engineering of mammalian cells in culture. Metabolic Engineering. 20: 212-20. PMID 24055788 DOI: 10.1016/J.Ymben.2013.09.004 |
0.769 |
|
2012 |
Le H, Kabbur S, Pollastrini L, Sun Z, Mills K, Johnson K, Karypis G, Hu WS. Multivariate analysis of cell culture bioprocess data--lactate consumption as process indicator. Journal of Biotechnology. 162: 210-23. PMID 22974585 DOI: 10.1016/J.Jbiotec.2012.08.021 |
0.607 |
|
2012 |
Castro-Melchor M, Le H, Hu WS. Transcriptome data analysis for cell culture processes. Advances in Biochemical Engineering/Biotechnology. 127: 27-70. PMID 22194060 DOI: 10.1007/10_2011_116 |
0.747 |
|
2011 |
Le H, Castro-Melchor M, Hakemeyer C, Jung C, Szperalski B, Karypis G, Hu WS. Discerning key parameters influencing high productivity and quality through recognition of patterns in process data. Bmc Proceedings. 5: P91. PMID 22373092 DOI: 10.1186/1753-6561-5-S8-P91 |
0.736 |
|
2010 |
Charaniya S, Le H, Rangwala H, Mills K, Johnson K, Karypis G, Hu WS. Mining manufacturing data for discovery of high productivity process characteristics. Journal of Biotechnology. 147: 186-97. PMID 20416347 DOI: 10.1016/J.Jbiotec.2010.04.005 |
0.786 |
|
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