| Year |
Citation |
Score |
| 2024 |
Singh A, Ottavi S, Krieger I, Planck K, Perkowski A, Kaneko T, Davis AM, Suh C, Zhang D, Goullieux L, Alex A, Roubert C, Gardner M, Preston M, Smith DM, ... ... Sacchettini JC, et al. Redirecting raltitrexed from cancer cell thymidylate synthase to phosphopantetheinyl transferase. Science Advances. 10: eadj6406. PMID 38489355 DOI: 10.1126/sciadv.adj6406 |
0.306 |
|
| 2022 |
Singh V, Grzegorzewicz AE, Fienberg S, Müller R, Khonde LP, Sanz O, Alfonso S, Urones B, Drewes G, Bantscheff M, Ghidelli-Disse S, Ioerger TR, Angala B, Liu J, Lee RE, ... Sacchettini JC, et al. 1,3-Diarylpyrazolyl-acylsulfonamides Target HadAB/BC Complex in . Acs Infectious Diseases. 8: 2315-2326. PMID 36325756 DOI: 10.1021/acsinfecdis.2c00392 |
0.308 |
|
| 2020 |
Khan D, Lee D, Gulten G, Aggarwal A, Wofford J, Krieger I, Tripathi A, Patrick JW, Eckert DM, Laganowsky A, Sacchettini J, Lindahl P, Bankaitis VA. A Sec14-like phosphatidylinositol transfer protein paralog defines a novel class of heme-binding proteins. Elife. 9. PMID 32780017 DOI: 10.7554/Elife.57081 |
0.358 |
|
| 2020 |
Lopez Quezada L, Smith R, Lupoli TJ, Edoo Z, Li X, Gold B, Roberts J, Ling Y, Park SW, Nguyen Q, Schoenen FJ, Li K, Hugonnet JE, Arthur M, Sacchettini JC, et al. Activity-Based Protein Profiling Reveals That Cephalosporins Selectively Active on Non-replicating Bind Multiple Protein Families and Spare Peptidoglycan Transpeptidases. Frontiers in Microbiology. 11: 1248. PMID 32655524 DOI: 10.3389/Fmicb.2020.01248 |
0.375 |
|
| 2020 |
Krieger I, Kuznetsov V, Chang JY, Zhang J, Moussa S, Young R, Sacchettini JC. The Structural Basis of T4 Phage Lysis Control: DNA as the Signal for Lysis Inhibition. Journal of Molecular Biology. PMID 32562709 DOI: 10.1016/J.Jmb.2020.06.013 |
0.319 |
|
| 2020 |
Jansen RS, Mandyoli L, Hughes R, Wakabayashi S, Pinkham JT, Selbach B, Guinn KM, Rubin EJ, Sacchettini JC, Rhee KY. Aspartate aminotransferase Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis. Nature Communications. 11: 1960. PMID 32327655 DOI: 10.1038/S41467-020-15876-8 |
0.388 |
|
| 2020 |
Taira J, Umei T, Inoue K, Kitamura M, Berenger F, Sacchettini JC, Sakamoto H, Aoki S. Improvement of the novel inhibitor for Mycobacterium enoyl-acyl carrier protein reductase (InhA): a structure-activity relationship study of KES4 assisted by in silico structure-based drug screening. The Journal of Antibiotics. PMID 32152525 DOI: 10.1038/S41429-020-0293-6 |
0.394 |
|
| 2020 |
Sun Q, Li X, Perez LM, Shi W, Zhang Y, Sacchettini JC. The molecular basis of pyrazinamide activity on Mycobacterium tuberculosis PanD. Nature Communications. 11: 339. PMID 31953389 DOI: 10.2210/Pdb6Oyy/Pdb |
0.428 |
|
| 2020 |
Khan D, Lee D, Gulten G, Aggarwal A, Wofford J, Krieger I, Tripathi A, Patrick JW, Eckert DM, Laganowsky A, Sacchettini J, Lindahl P, Bankaitis VA. Author response: A Sec14-like phosphatidylinositol transfer protein paralog defines a novel class of heme-binding proteins Elife. DOI: 10.7554/Elife.57081.Sa2 |
0.319 |
|
| 2019 |
Mosior J, Bourland R, Soma S, Nathan C, Sacchettini J. Structural Insights into Phosphopantetheinyl Hydrolase PptH from Mycobacterium tuberculosis. Protein Science : a Publication of the Protein Society. PMID 31886928 DOI: 10.1002/Pro.3813 |
0.462 |
|
| 2019 |
Tang S, Hicks ND, Cheng YS, Silva A, Fortune SM, Sacchettini JC. Structural and functional insight into the Mycobacterium tuberculosis protein PrpR reveals a novel type of transcription factor. Nucleic Acids Research. PMID 31504787 DOI: 10.1093/Nar/Gkz724 |
0.348 |
|
| 2019 |
Brown EE, Miller AK, Krieger IV, Otto RM, Sacchettini JC, Herman JK. A DNA-binding protein tunes septum placement during sporulation. Journal of Bacteriology. PMID 31160399 DOI: 10.1128/Jb.00287-19 |
0.315 |
|
| 2019 |
Farhat MR, Freschi L, Calderon R, Ioerger T, Snyder M, Meehan CJ, de Jong B, Rigouts L, Sloutsky A, Kaur D, Sunyaev S, van Soolingen D, Shendure J, Sacchettini J, Murray M. GWAS for quantitative resistance phenotypes in Mycobacterium tuberculosis reveals resistance genes and regulatory regions. Nature Communications. 10: 2128. PMID 31086182 DOI: 10.1038/S41467-019-10110-6 |
0.317 |
|
| 2019 |
Crespo RA, Dang Q, Zhou NE, Guthrie LM, Snavely TC, Dong W, Loesch KA, Suzuki T, You L, Wang W, O'Malley T, Parish T, Olsen DB, Sacchettini JC. Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase. Journal of Medicinal Chemistry. PMID 31002508 DOI: 10.2210/Pdb6C9P/Pdb |
0.435 |
|
| 2019 |
Salazar AJ, Sherekar M, Tsai J, Sacchettini JC. R pyocin tail fiber structure reveals a receptor-binding domain with a lectin fold. Plos One. 14: e0211432. PMID 30721244 DOI: 10.2210/Pdb6Cxb/Pdb |
0.319 |
|
| 2019 |
Ballinger E, Mosior J, Hartman T, Burns-Huang K, Gold B, Morris R, Goullieux L, Blanc I, Vaubourgeix J, Lagrange S, Fraisse L, Sans S, Couturier C, Bacqué E, Rhee K, ... ... Sacchettini J, et al. Opposing reactions in coenzyme A metabolism sensitize to enzyme inhibition. Science (New York, N.Y.). 363. PMID 30705156 DOI: 10.1126/Science.Aau8959 |
0.404 |
|
| 2019 |
Miller BK, Hughes R, Ligon LS, Rigel NW, Malik S, Anjuwon-Foster BR, Sacchettini JC, Braunstein M. SatS is a chaperone for the SecA2 protein export pathway. Elife. 8. PMID 30604681 DOI: 10.7554/Elife.40063 |
0.373 |
|
| 2018 |
Rittershaus ESC, Baek SH, Krieger IV, Nelson SJ, Cheng YS, Nambi S, Baker RE, Leszyk JD, Shaffer SA, Sacchettini JC, Sassetti CM. A Lysine Acetyltransferase Contributes to the Metabolic Adaptation to Hypoxia in Mycobacterium tuberculosis. Cell Chemical Biology. PMID 30318462 DOI: 10.1016/J.Chembiol.2018.09.009 |
0.377 |
|
| 2018 |
Melief E, Kokoczka R, Files M, Bailey MA, Alling T, Li H, Ahn J, Misquith A, Korkegian A, Roberts D, Sacchettini J, Parish T. Construction of an overexpression library for . Biology Methods & Protocols. 3: bpy009. PMID 30197930 DOI: 10.1093/Biomethods/Bpy009 |
0.348 |
|
| 2018 |
Ellenbarger J, Krieger I, Huang HL, Gómez-Coca S, Ioerger TR, Sacchettini JC, Wheeler SE, Dunbar KR. Anion-π Interactions in Computer-Aided Drug Design: Modeling the Inhibition of Malate Synthase by Phenyl-Diketo Acids. Journal of Chemical Information and Modeling. PMID 30137983 DOI: 10.1021/acs.jcim.8b00417 |
0.392 |
|
| 2018 |
Shen Q, Bhatt VS, Krieger I, Sacchettini JC, Cho JH. Structure-guided design of a potent peptide inhibitor targeting the interaction between CRK and ABL kinase. Medchemcomm. 9: 519-524. PMID 30108942 DOI: 10.1039/C7Md00619E |
0.301 |
|
| 2018 |
Blanc L, Sarathy JP, Alvarez Cabrera N, O'Brien P, Dias-Freedman I, Mina M, Sacchettini J, Savic RM, Gengenbacher M, Podell BK, Prideaux B, Ioerger T, Dick T, Dartois V. Impact of immunopathology on the antituberculous activity of pyrazinamide. The Journal of Experimental Medicine. PMID 30018074 DOI: 10.1084/Jem.20180518 |
0.305 |
|
| 2018 |
Tiwari D, Park SW, Essawy MM, Dawadi S, Mason A, Nandakumar M, Zimmerman M, Mina M, Ho HP, Engelhart CA, Ioerger T, Sacchettini JC, Rhee K, Ehrt S, Aldrich CC, et al. Targeting protein biotinylation enhances tuberculosis chemotherapy. Science Translational Medicine. 10. PMID 29695454 DOI: 10.1126/Scitranslmed.Aal1803 |
0.378 |
|
| 2018 |
Korkegian A, O'Malley T, Xia Y, Zhou Y, Carter DS, Sunde B, Flint L, Thompson D, Ioerger TR, Sacchettini J, Alley MRK, Parish T. The 7-phenyl benzoxaborole series is active against Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland). 108: 96-98. PMID 29523334 DOI: 10.1016/J.Tube.2017.11.003 |
0.351 |
|
| 2018 |
Murugesan D, Ray PC, Bayliss T, Prosser GA, Harrison JR, Green K, Soares de Melo C, Feng TS, Street LJ, Chibale K, Warner DF, Mizrahi V, Epemolu O, Scullion P, Ellis L, ... ... Sacchettini J, et al. 2-Mercapto-quinazolinones as inhibitors of NDH-2 and Mycobacterium tuberculosis: Structure-activity relationships, mechanism of action and ADME characterization. Acs Infectious Diseases. PMID 29522317 DOI: 10.1021/Acsinfecdis.7B00275 |
0.455 |
|
| 2018 |
Negri A, Javidnia P, Mu R, Zhang X, Vendome J, Gold B, Roberts J, Barman D, Ioerger T, Sacchettini JC, Jiang X, Burns-Huang K, Warrier T, Ling Y, Warren JD, et al. Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis. Acs Infectious Diseases. PMID 29465985 DOI: 10.1021/Acsinfecdis.7B00111 |
0.373 |
|
| 2018 |
Miller BK, Hughes R, Ligon LS, Rigel NW, Malik S, Anjuwon-Foster BR, Sacchettini JC, Braunstein M. Author response: Mycobacterium tuberculosis SatS is a chaperone for the SecA2 protein export pathway Elife. DOI: 10.7554/Elife.40063.028 |
0.328 |
|
| 2017 |
Lehmann J, Cheng TY, Aggarwal A, Park AS, Zeiler E, Raju RM, Akopian T, Kandror O, Bach NC, Sacchettini JC, Moody DB, Rubin EJ, Sieber SA. An antibacterial β-lactone kills Mycobacterium tuberculosis by infiltrating mycolic acid biosynthesis. Angewandte Chemie (International Ed. in English). PMID 29067779 DOI: 10.1002/Anie.201709365 |
0.383 |
|
| 2017 |
Chandrasekara NS, Berube BJ, Shetye G, Chettiar S, O'Malley T, Manning A, Flint L, Awasthi D, Ioerger TR, Sacchettini JC, Masquelin T, Hipskind PA, Odingo J, Parish T. Improved phenoxyalkylbenzimidazoles with activity against Mycobacterium tuberculosis appear to target QcrB. Acs Infectious Diseases. PMID 29035551 DOI: 10.1021/Acsinfecdis.7B00112 |
0.379 |
|
| 2017 |
Yang K, Chang JY, Cui Z, Li X, Meng R, Duan L, Thongchol J, Jakana J, Huwe CM, Sacchettini JC, Zhang J. Structural insights into species-specific features of the ribosome from the human pathogen Mycobacterium tuberculosis. Nucleic Acids Research. PMID 28977617 DOI: 10.1093/Nar/Gkx785 |
0.378 |
|
| 2017 |
Taira J, Morita K, Kawashima S, Umei T, Baba H, Maruoka T, Komatsu H, Sakamoto H, Sacchettini JC, Aoki S. Identification of a novel class of small compounds with anti-tuberculosis activity by in silico structure-based drug screening. The Journal of Antibiotics. PMID 28951604 DOI: 10.1038/Ja.2017.106 |
0.4 |
|
| 2017 |
Yadon AN, Maharaj K, Adamson JH, Lai YP, Sacchettini JC, Ioerger TR, Rubin EJ, Pym AS. A comprehensive characterization of PncA polymorphisms that confer resistance to pyrazinamide. Nature Communications. 8: 588. PMID 28928454 DOI: 10.1038/S41467-017-00721-2 |
0.318 |
|
| 2017 |
Thapa HR, Tang S, Sacchettini JC, Devarenne TP. Tetraterpene synthase substrate and product specificity in the green microalga Botryococcus braunii race L. Acs Chemical Biology. PMID 28813599 DOI: 10.1021/Acschembio.7B00457 |
0.358 |
|
| 2017 |
Pham TV, Murkin AS, Moynihan MM, Harris L, Tyler PC, Shetty N, Sacchettini JC, Huang HL, Meek TD. Mechanism-based inactivator of isocitrate lyases 1 and 2 from Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28679637 DOI: 10.1073/Pnas.1706134114 |
0.39 |
|
| 2017 |
Patel N, O'Malley T, Zhang YK, Xia Y, Sunde B, Flint L, Korkegian A, Ioerger TR, Sacchettini J, Alley MRK, Parish T. A novel 6-benzyl ether benzoxaborole is active against Mycobacterium tuberculosis in vitro. Antimicrobial Agents and Chemotherapy. PMID 28674058 DOI: 10.1128/Aac.01205-17 |
0.336 |
|
| 2017 |
Aggarwal A, Parai MK, Shetty N, Wallis D, Woolhiser L, Hastings C, Dutta NK, Galaviz S, Dhakal RC, Shrestha R, Wakabayashi S, Walpole C, Matthews D, Floyd D, Scullion P, ... ... Sacchettini JC, et al. Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13. Cell. PMID 28669536 DOI: 10.1016/J.Cell.2017.06.025 |
0.403 |
|
| 2017 |
Perkowski EF, Zulauf KE, Weerakoon D, Hayden JD, Ioerger TR, Oreper D, Gomez SM, Sacchettini JC, Braunstein M. The EXIT Strategy: an Approach for Identifying Bacterial Proteins Exported during Host Infection. Mbio. 8. PMID 28442606 DOI: 10.1128/Mbio.00333-17 |
0.344 |
|
| 2017 |
Puckett S, Trujillo C, Wang Z, Eoh H, Ioerger TR, Krieger I, Sacchettini J, Schnappinger D, Rhee KY, Ehrt S. Glyoxylate detoxification is an essential function of malate synthase required for carbon assimilation in Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28265055 DOI: 10.1073/Pnas.1617655114 |
0.337 |
|
| 2017 |
Zhu M, Harshbarger WD, Robles O, Krysiak J, Hull KG, Cho SW, Richardson RD, Yang Y, Garcia A, Spiegelman L, Ramirez B, Wilson CT, Yau JA, Moore JT, Walker CB, ... Sacchettini JC, et al. A strategy for dual inhibition of the proteasome and fatty acid synthase with belactosin C-orlistat hybrids. Bioorganic & Medicinal Chemistry. PMID 28236510 DOI: 10.1016/J.Bmc.2017.01.020 |
0.385 |
|
| 2016 |
Huang HL, Krieger IV, Parai MK, Gawandi VB, Sacchettini JC. Mycobacterium tuberculosis Malate Synthase Structures with Fragments Reveal a Portal for Substrate/Product Exchange. The Journal of Biological Chemistry. PMID 27738104 DOI: 10.1074/Jbc.M116.750877 |
0.452 |
|
| 2016 |
Park Y, Pacitto A, Bayliss T, Cleghorn LA, Wang Z, Hartman T, Arora K, Ioerger TR, Sacchettini J, Rizzi M, Donini S, Blundell TL, Ascher DB, Rhee KY, Breda A, et al. Essential but not vulnerable: indazole sulfonamides targeting inosine monophosphate dehydrogenase as potential leads against Mycobacterium tuberculosis. Acs Infectious Diseases. PMID 27704782 DOI: 10.1021/Acsinfecdis.6B00103 |
0.408 |
|
| 2016 |
Palencia A, Li X, Bu W, Choi W, Ding CZ, Easom EE, Feng L, Hernandez V, Houston P, Liu L, Meewan M, Mohan M, Rock FL, Sexton H, Zhang S, ... ... Sacchettini JC, et al. Discovery of novel oral protein synthesis inhibitors of Mycobacterium tuberculosis that target leucyl-tRNA synthetase. Antimicrobial Agents and Chemotherapy. PMID 27503647 DOI: 10.1128/Aac.01339-16 |
0.41 |
|
| 2016 |
Martínez-Hoyos M, Perez-Herran E, Gulten G, Encinas L, Álvarez-Gómez D, Alvarez E, Ferrer-Bazaga S, García-Pérez A, Ortega F, Angulo-Barturen I, Rullas-Trincado J, Blanco Ruano D, Torres P, Castañeda P, Huss S, ... ... Sacchettini JC, et al. Antitubercular drugs for an old target: GSK693 as a promising InhA direct inhibitor. Ebiomedicine. 8: 291-301. PMID 27428438 DOI: 10.1016/J.Ebiom.2016.05.006 |
0.397 |
|
| 2016 |
Bhatt VS, Zeng D, Krieger I, Sacchettini JC, Cho JH. Binding Mechanism of the N-Terminal SH3 Domain of CrkII and Proline-Rich Motifs in cAbl. Biophysical Journal. 110: 2630-2641. PMID 27332121 DOI: 10.1016/J.Bpj.2016.05.008 |
0.354 |
|
| 2016 |
Almeida D, Ioerger T, Tyagi S, Li SY, Mdluli K, Andries K, Grosset J, Sacchettini J, Nuermberger E. Mutations in pepQ Confer Low-level Resistance to Bedaquiline and Clofazimine in Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy. PMID 27185800 DOI: 10.1128/Aac.00753-16 |
0.335 |
|
| 2016 |
Guardia A, Gulten G, Fernandez R, Gómez J, Wang F, Convery M, Blanco D, Martínez M, Pérez-Herrán E, Alonso M, Ortega F, Rullás J, Calvo D, Mata L, Young R, ... Sacchettini JC, et al. N-Benzyl-4-((heteroaryl)methyl)benzamides: A New Class of Direct NADH-Dependent 2-trans Enoyl-Acyl Carrier Protein Reductase (InhA) Inhibitors with Antitubercular Activity. Chemmedchem. PMID 26934341 DOI: 10.1002/Cmdc.201600020 |
0.455 |
|
| 2016 |
Bageshwar UK, VerPlank L, Baker D, Dong W, Hamsanathan S, Whitaker N, Sacchettini JC, Musser SM. High Throughput Screen for Escherichia coli Twin Arginine Translocation (Tat) Inhibitors. Plos One. 11: e0149659. PMID 26901445 DOI: 10.1371/Journal.Pone.0149659 |
0.329 |
|
| 2016 |
Cheng YS, Sacchettini JC. Structural Insights into Mycobacterium tuberculosis Rv2671 Protein as a Dihydrofolate Reductase Functional Analogue Contributing to para-Aminosalicylic Acid Resistance. Biochemistry. PMID 26848874 DOI: 10.1021/Acs.Biochem.5B00993 |
0.47 |
|
| 2016 |
Martinot AJ, Farrow M, Bai L, Layre E, Cheng TY, Tsai JH, Iqbal J, Annand JW, Sullivan ZA, Hussain MM, Sacchettini J, Moody DB, Seeliger JC, Rubin EJ. Mycobacterial Metabolic Syndrome: LprG and Rv1410 Regulate Triacylglyceride Levels, Growth Rate and Virulence in Mycobacterium tuberculosis. Plos Pathogens. 12: e1005351. PMID 26751071 DOI: 10.1371/Journal.Ppat.1005351 |
0.3 |
|
| 2015 |
Swanson S, Ioerger TR, Rigel NW, Miller BK, Braunstein M, Sacchettini JC. Structural similarities and differences between two functionally distinct SecA proteins: the Mycobacterium tuberculosis SecA1 and SecA2. Journal of Bacteriology. PMID 26668263 DOI: 10.1128/Jb.00696-15 |
0.414 |
|
| 2015 |
Maksymiuk C, Ioerger T, Balakrishnan A, Bryk R, Rhee K, Sacchettini J, Nathan C. Comparison of transposon and deletion mutants in Mycobacterium tuberculosis: The case of rv1248c, encoding 2-hydroxy-3-oxoadipate synthase. Tuberculosis (Edinburgh, Scotland). 95: 689-94. PMID 26547230 DOI: 10.1016/J.Tube.2015.08.009 |
0.315 |
|
| 2015 |
Hong W, Wang Y, Chang Z, Yang Y, Pu J, Sun T, Kaur S, Sacchettini JC, Jung H, Lin Wong W, Fah Yap L, Fong Ngeow Y, Paterson IC, Wang H. The identification of novel Mycobacterium tuberculosis DHFR inhibitors and the investigation of their binding preferences by using molecular modelling. Scientific Reports. 5: 15328. PMID 26471125 DOI: 10.1038/Srep15328 |
0.412 |
|
| 2015 |
Kieser KJ, Baranowski C, Chao MC, Long JE, Sassetti CM, Waldor MK, Sacchettini JC, Ioerger TR, Rubin EJ. Peptidoglycan synthesis in Mycobacterium tuberculosis is organized into networks with varying drug susceptibility. Proceedings of the National Academy of Sciences of the United States of America. 112: 13087-92. PMID 26438867 DOI: 10.1073/Pnas.1514135112 |
0.353 |
|
| 2015 |
Li X, Sun Q, Jiang C, Yang K, Hung LW, Zhang J, Sacchettini JC. Structure of Ribosomal Silencing Factor Bound to Mycobacterium tuberculosis Ribosome. Structure (London, England : 1993). PMID 26299947 DOI: 10.1016/J.Str.2015.07.014 |
0.398 |
|
| 2015 |
Kanetaka H, Koseki Y, Taira J, Umei T, Komatsu H, Sakamoto H, Gulten G, Sacchettini JC, Kitamura M, Aoki S. Discovery of InhA inhibitors with anti-mycobacterial activity through a matched molecular pair approach. European Journal of Medicinal Chemistry. 94: 378-85. PMID 25778993 DOI: 10.1016/J.Ejmech.2015.02.062 |
0.422 |
|
| 2015 |
Harshbarger W, Miller C, Diedrich C, Sacchettini J. Crystal structure of the human 20S proteasome in complex with carfilzomib Structure. 23: 418-424. DOI: 10.1016/J.Str.2014.11.017 |
0.385 |
|
| 2014 |
Prigozhin DM, Krieger IV, Huizar JP, Mavrici D, Waldo GS, Hung LW, Sacchettini JC, Terwilliger TC, Alber T. Subfamily-specific adaptations in the structures of two penicillin-binding proteins from Mycobacterium tuberculosis. Plos One. 9: e116249. PMID 25551456 DOI: 10.1371/Journal.Pone.0116249 |
0.471 |
|
| 2014 |
Odingo J, O'Malley T, Kesicki EA, Alling T, Bailey MA, Early J, Ollinger J, Dalai S, Kumar N, Singh RV, Hipskind PA, Cramer JW, Ioerger T, Sacchettini J, Vickers R, et al. Synthesis and evaluation of the 2,4-diaminoquinazoline series as anti-tubercular agents. Bioorganic & Medicinal Chemistry. 22: 6965-79. PMID 25456390 DOI: 10.1016/J.Bmc.2014.10.007 |
0.385 |
|
| 2014 |
Reddy MC, Breda A, Bruning JB, Sherekar M, Valluru S, Thurman C, Ehrenfeld H, Sacchettini JC. Structure, activity, and inhibition of the Carboxyltransferase β-subunit of acetyl coenzyme A carboxylase (AccD6) from Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy. 58: 6122-32. PMID 25092705 DOI: 10.1128/Aac.02574-13 |
0.417 |
|
| 2014 |
Nixon MR, Saionz KW, Koo MS, Szymonifka MJ, Jung H, Roberts JP, Nandakumar M, Kumar A, Liao R, Rustad T, Sacchettini JC, Rhee KY, Freundlich JS, Sherman DR. Folate pathway disruption leads to critical disruption of methionine derivatives in Mycobacterium tuberculosis. Chemistry & Biology. 21: 819-30. PMID 24954008 DOI: 10.1016/J.Chembiol.2014.04.009 |
0.36 |
|
| 2014 |
Kim Y, Cunningham M, Tesar C, Jedrzejczak R, Mire J, Binkowski A, Babnigg G, Sacchettini J, Joachimiak A. Carbapenemase NDM-1, Structural Analysis of the Catalytic Mechanism Acta Crystallographica Section A. 70. DOI: 10.1107/S2053273314091815 |
0.331 |
|
| 2013 |
Ngubane NA, Gresh L, Ioerger TR, Sacchettini JC, Zhang YJ, Rubin EJ, Pym A, Khati M. High-throughput sequencing enhanced phage display identifies peptides that bind mycobacteria. Plos One. 8: e77844. PMID 24265677 DOI: 10.1371/Journal.Pone.0077844 |
0.313 |
|
| 2013 |
Ioerger TR, O'Malley T, Liao R, Guinn KM, Hickey MJ, Mohaideen N, Murphy KC, Boshoff HI, Mizrahi V, Rubin EJ, Sassetti CM, Barry CE, Sherman DR, Parish T, Sacchettini JC. Identification of new drug targets and resistance mechanisms in Mycobacterium tuberculosis. Plos One. 8: e75245. PMID 24086479 DOI: 10.1371/Journal.Pone.0075245 |
0.404 |
|
| 2013 |
Gulten G, Sacchettini JC. Structure of the Mtb CarD/RNAP β-lobes complex reveals the molecular basis of interaction and presents a distinct DNA-binding domain for Mtb CarD. Structure (London, England : 1993). 21: 1859-69. PMID 24055315 DOI: 10.1016/J.Str.2013.08.014 |
0.368 |
|
| 2013 |
Small JL, Park SW, Kana BD, Ioerger TR, Sacchettini JC, Ehrt S. Perturbation of cytochrome c maturation reveals adaptability of the respiratory chain in Mycobacterium tuberculosis. Mbio. 4: e00475-13. PMID 24045640 DOI: 10.1128/Mbio.00475-13 |
0.365 |
|
| 2013 |
Lanzas F, Karakousis PC, Sacchettini JC, Ioerger TR. Multidrug-resistant tuberculosis in panama is driven by clonal expansion of a multidrug-resistant Mycobacterium tuberculosis strain related to the KZN extensively drug-resistant M. tuberculosis strain from South Africa. Journal of Clinical Microbiology. 51: 3277-85. PMID 23884993 DOI: 10.1128/Jcm.01122-13 |
0.322 |
|
| 2013 |
Mosser R, Reddy MC, Bruning JB, Sacchettini JC, Reinhart GD. Redefining the role of the quaternary shift in Bacillus stearothermophilus phosphofructokinase. Biochemistry. 52: 5421-9. PMID 23859543 DOI: 10.1021/Bi4002503 |
0.399 |
|
| 2013 |
Stanley SA, Kawate T, Iwase N, Shimizu M, Clatworthy AE, Kazyanskaya E, Sacchettini JC, Ioerger TR, Siddiqi NA, Minami S, Aquadro JA, Grant SS, Rubin EJ, Hung DT. Diarylcoumarins inhibit mycolic acid biosynthesis and kill Mycobacterium tuberculosis by targeting FadD32. Proceedings of the National Academy of Sciences of the United States of America. 110: 11565-70. PMID 23798446 DOI: 10.1073/Pnas.1302114110 |
0.41 |
|
| 2013 |
Liu Z, Ioerger TR, Wang F, Sacchettini JC. Structures of Mycobacterium tuberculosis FadD10 protein reveal a new type of adenylate-forming enzyme. The Journal of Biological Chemistry. 288: 18473-83. PMID 23625916 DOI: 10.1074/Jbc.M113.466912 |
0.44 |
|
| 2013 |
Gokulan K, O'Leary SE, Russell WK, Russell DH, Lalgondar M, Begley TP, Ioerger TR, Sacchettini JC. Crystal structure of Mycobacterium tuberculosis polyketide synthase 11 (PKS11) reveals intermediates in the synthesis of methyl-branched alkylpyrones. The Journal of Biological Chemistry. 288: 16484-94. PMID 23615910 DOI: 10.1074/Jbc.M113.468892 |
0.43 |
|
| 2013 |
Kinjo T, Koseki Y, Kobayashi M, Yamada A, Morita K, Yamaguchi K, Tsurusawa R, Gulten G, Komatsu H, Sakamoto H, Sacchettini JC, Kitamura M, Aoki S. Identification of compounds with potential antibacterial activity against Mycobacterium through structure-based drug screening. Journal of Chemical Information and Modeling. 53: 1200-12. PMID 23600706 DOI: 10.1021/Ci300571N |
0.388 |
|
| 2013 |
Gopinath K, Venclovas C, Ioerger TR, Sacchettini JC, McKinney JD, Mizrahi V, Warner DF. A vitamin B₁₂ transporter in Mycobacterium tuberculosis. Open Biology. 3: 120175. PMID 23407640 DOI: 10.1098/Rsob.120175 |
0.364 |
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| 2013 |
Kim Y, Cunningham MA, Mire J, Tesar C, Sacchettini J, Joachimiak A. NDM-1, the ultimate promiscuous enzyme: substrate recognition and catalytic mechanism The Faseb Journal. 27: 1917-1927. PMID 23363572 DOI: 10.1096/Fj.12-224014 |
0.356 |
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| 2013 |
Anderson JW, Sarantakis D, Terpinski J, Kumar TR, Tsai HC, Kuo M, Ager AL, Jacobs WR, Schiehser GA, Ekins S, Sacchettini JC, Jacobus DP, Fidock DA, Freundlich JS. Novel diaryl ureas with efficacy in a mouse model of malaria. Bioorganic & Medicinal Chemistry Letters. 23: 1022-5. PMID 23313245 DOI: 10.1016/J.Bmcl.2012.12.022 |
0.776 |
|
| 2013 |
DeJesus MA, Sacchettini JC, Ioerger TR. Reannotation of translational start sites in the genome of Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland). 93: 18-25. PMID 23273318 DOI: 10.1016/J.Tube.2012.11.012 |
0.319 |
|
| 2012 |
Krieger IV, Freundlich JS, Gawandi VB, Roberts JP, Gawandi VB, Sun Q, Owen JL, Fraile MT, Huss SI, Lavandera JL, Ioerger TR, Sacchettini JC. Structure-guided discovery of phenyl-diketo acids as potent inhibitors of M. tuberculosis malate synthase. Chemistry & Biology. 19: 1556-67. PMID 23261599 DOI: 10.1016/J.Chembiol.2012.09.018 |
0.448 |
|
| 2012 |
Xie H, Mire J, Kong Y, Chang M, Hassounah HA, Thornton CN, Sacchettini JC, Cirillo JD, Rao J. Rapid point-of-care detection of the tuberculosis pathogen using a BlaC-specific fluorogenic probe. Nature Chemistry. 4: 802-9. PMID 23000993 DOI: 10.1038/Nchem.1435 |
0.328 |
|
| 2012 |
James JN, Hasan ZU, Ioerger TR, Brown AC, Personne Y, Carroll P, Ikeh M, Tilston-Lunel NL, Palavecino C, Sacchettini JC, Parish T. Deletion of SenX3-RegX3, a key two-component regulatory system of Mycobacterium smegmatis, results in growth defects under phosphate-limiting conditions. Microbiology (Reading, England). 158: 2724-31. PMID 22956756 DOI: 10.1099/Mic.0.060319-0 |
0.302 |
|
| 2012 |
Chia BS, Lanzas F, Rifat D, Herrera A, Kim EY, Sailer C, Torres-Chavolla E, Narayanaswamy P, Einarsson V, Bravo J, Pascale JM, Ioerger TR, Sacchettini JC, Karakousis PC. Use of multiplex allele-specific polymerase chain reaction (MAS-PCR) to detect multidrug-resistant tuberculosis in Panama. Plos One. 7: e40456. PMID 22792333 DOI: 10.1371/Journal.Pone.0040456 |
0.327 |
|
| 2012 |
Moussa SH, Kuznetsov V, Tran TA, Sacchettini JC, Young R. Protein determinants of phage T4 lysis inhibition. Protein Science : a Publication of the Protein Society. 21: 571-82. PMID 22389108 DOI: 10.1002/Pro.2042 |
0.303 |
|
| 2012 |
Mosser R, Reddy MC, Bruning JB, Sacchettini JC, Reinhart GD. Structure of the apo form of Bacillus stearothermophilus phosphofructokinase. Biochemistry. 51: 769-75. PMID 22212099 DOI: 10.1021/Bi201548P |
0.395 |
|
| 2012 |
La Rosa V, Poce G, Canseco JO, Buroni S, Pasca MR, Biava M, Raju RM, Porretta GC, Alfonso S, Battilocchio C, Javid B, Sorrentino F, Ioerger TR, Sacchettini JC, Manetti F, et al. MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212. Antimicrobial Agents and Chemotherapy. 56: 324-31. PMID 22024828 DOI: 10.1128/Aac.05270-11 |
0.386 |
|
| 2011 |
Kim Y, Tesar C, Mire J, Jedrzejczak R, Binkowski A, Babnigg G, Sacchettini JC, Joachimiak A. Structure of apo- and monometalated forms of NDM-1--a highly potent carbapenem-hydrolyzing metallo-β-lactamase. Plos One. 6. PMID 21931780 DOI: 10.1371/Journal.Pone.0024621 |
0.324 |
|
| 2011 |
Lotesta SD, Liu J, Yates EV, Krieger I, Sacchettini JC, Freundlich JS, Sorensen EJ. Expanding the pleuromutilin class of antibiotics by de novo chemical synthesis. Chemical Science (Royal Society of Chemistry : 2010). 2: 1258-1261. PMID 21874155 DOI: 10.1039/C1Sc00116G |
0.38 |
|
| 2011 |
Gokulan K, Aggarwal A, Shipman L, Besra GS, Sacchettini JC. Mycobacterium tuberculosis acyl carrier protein synthase adopts two different pH-dependent structural conformations. Acta Crystallographica. Section D, Biological Crystallography. 67: 657-69. PMID 21697604 DOI: 10.1107/S0907444911020221 |
0.781 |
|
| 2011 |
Vilchèze C, Baughn AD, Tufariello J, Leung LW, Kuo M, Basler CF, Alland D, Sacchettini JC, Freundlich JS, Jacobs WR. Novel inhibitors of InhA efficiently kill Mycobacterium tuberculosis under aerobic and anaerobic conditions. Antimicrobial Agents and Chemotherapy. 55: 3889-98. PMID 21628538 DOI: 10.1128/Aac.00266-11 |
0.794 |
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| 2011 |
Ford CB, Lin PL, Chase MR, Shah RR, Iartchouk O, Galagan J, Mohaideen N, Ioerger TR, Sacchettini JC, Lipsitch M, Flynn JL, Fortune SM. Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection. Nature Genetics. 43: 482-6. PMID 21516081 DOI: 10.1038/Ng.811 |
0.307 |
|
| 2011 |
Picaud S, Kavanagh KL, Yue WW, Lee WH, Muller-Knapp S, Gileadi O, Sacchettini J, Oppermann U. Structural basis of fumarate hydratase deficiency. Journal of Inherited Metabolic Disease. 34: 671-6. PMID 21445611 DOI: 10.1007/S10545-011-9294-8 |
0.349 |
|
| 2011 |
Dias MV, Snee WC, Bromfield KM, Payne RJ, Palaninathan SK, Ciulli A, Howard NI, Abell C, Sacchettini JC, Blundell TL. Structural investigation of inhibitor designs targeting 3-dehydroquinate dehydratase from the shikimate pathway of Mycobacterium tuberculosis. The Biochemical Journal. 436: 729-39. PMID 21410435 DOI: 10.1042/Bj20110002 |
0.46 |
|
| 2011 |
Arockiasamy A, Aggarwal A, Savva CG, Holzenburg A, Sacchettini JC. Crystal structure of calcium dodecin (Rv0379), from Mycobacterium tuberculosis with a unique calcium-binding site. Protein Science : a Publication of the Protein Society. 20: 827-33. PMID 21370306 DOI: 10.1002/Pro.607 |
0.358 |
|
| 2011 |
Chim N, Habel JE, Johnston JM, Krieger I, Miallau L, Sankaranarayanan R, Morse RP, Bruning J, Swanson S, Kim H, Kim CY, Li H, Bulloch EM, Payne RJ, Manos-Turvey A, ... ... Sacchettini JC, et al. The TB Structural Genomics Consortium: a decade of progress. Tuberculosis (Edinburgh, Scotland). 91: 155-72. PMID 21247804 DOI: 10.1016/J.Tube.2010.11.009 |
0.413 |
|
| 2011 |
Bruning JB, Murillo AC, Chacon O, Barletta RG, Sacchettini JC. Structure of the Mycobacterium tuberculosis D-alanine:D-alanine ligase, a target of the antituberculosis drug D-cycloserine. Antimicrobial Agents and Chemotherapy. 55: 291-301. PMID 20956591 DOI: 10.1128/Aac.00558-10 |
0.386 |
|
| 2010 |
Molle V, Gulten G, Vilchèze C, Veyron-Churlet R, Zanella-Cléon I, Sacchettini JC, Jacobs WR, Kremer L. Phosphorylation of InhA inhibits mycolic acid biosynthesis and growth of Mycobacterium tuberculosis. Molecular Microbiology. 78: 1591-605. PMID 21143326 DOI: 10.1111/J.1365-2958.2010.07446.X |
0.404 |
|
| 2010 |
Ioerger TR, Feng Y, Chen X, Dobos KM, Victor TC, Streicher EM, Warren RM, Gey van Pittius NC, Van Helden PD, Sacchettini JC. The non-clonality of drug resistance in Beijing-genotype isolates of Mycobacterium tuberculosis from the Western Cape of South Africa. Bmc Genomics. 11: 670. PMID 21110864 DOI: 10.1186/1471-2164-11-670 |
0.325 |
|
| 2010 |
Freundlich JS, Lalgondar M, Wei JR, Swanson S, Sorensen EJ, Rubin EJ, Sacchettini JC. The abyssomicin C family as in vitro inhibitors of Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland). 90: 298-300. PMID 20739223 DOI: 10.1016/J.Tube.2010.08.002 |
0.355 |
|
| 2010 |
Drage MG, Tsai HC, Pecora ND, Cheng TY, Arida AR, Shukla S, Rojas RE, Seshadri C, Moody DB, Boom WH, Sacchettini JC, Harding CV. Mycobacterium tuberculosis lipoprotein LprG (Rv1411c) binds triacylated glycolipid agonists of Toll-like receptor 2. Nature Structural & Molecular Biology. 17: 1088-95. PMID 20694006 DOI: 10.1038/Nsmb.1869 |
0.348 |
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| 2010 |
Kong Y, Yao H, Ren H, Subbian S, Cirillo SL, Sacchettini JC, Rao J, Cirillo JD. Imaging tuberculosis with endogenous beta-lactamase reporter enzyme fluorescence in live mice. Proceedings of the National Academy of Sciences of the United States of America. 107: 12239-44. PMID 20566877 DOI: 10.1073/Pnas.1000643107 |
0.317 |
|
| 2010 |
Wang F, Jain P, Gulten G, Liu Z, Feng Y, Ganesula K, Motiwala AS, Ioerger TR, Alland D, Vilchèze C, Jacobs WR, Sacchettini JC. Mycobacterium tuberculosis dihydrofolate reductase is not a target relevant to the antitubercular activity of isoniazid. Antimicrobial Agents and Chemotherapy. 54: 3776-82. PMID 20566771 DOI: 10.1128/Aac.00453-10 |
0.385 |
|
| 2010 |
Dey S, Lane JM, Lee RE, Rubin EJ, Sacchettini JC. Structural characterization of the Mycobacterium tuberculosis biotin biosynthesis enzymes 7,8-diaminopelargonic acid synthase and dethiobiotin synthetase . Biochemistry. 49: 6746-60. PMID 20565114 DOI: 10.1021/Bi902097J |
0.655 |
|
| 2010 |
Shetty ND, Reddy MC, Palaninathan SK, Owen JL, Sacchettini JC. Crystal structures of the apo and ATP bound Mycobacterium tuberculosis nitrogen regulatory PII protein. Protein Science : a Publication of the Protein Society. 19: 1513-24. PMID 20521335 DOI: 10.1002/Pro.430 |
0.423 |
|
| 2010 |
Kalscheuer R, Syson K, Veeraraghavan U, Weinrick B, Biermann KE, Liu Z, Sacchettini JC, Besra G, Bornemann S, Jacobs WR. Self-poisoning of Mycobacterium tuberculosis by targeting GlgE in an alpha-glucan pathway. Nature Chemical Biology. 6: 376-84. PMID 20305657 DOI: 10.1038/Nchembio.340 |
0.348 |
|
| 2010 |
Kana BD, Abrahams GL, Sung N, Warner DF, Gordhan BG, Machowski EE, Tsenova L, Sacchettini JC, Stoker NG, Kaplan G, Mizrahi V. Role of the DinB homologs Rv1537 and Rv3056 in Mycobacterium tuberculosis. Journal of Bacteriology. 192: 2220-7. PMID 20139184 DOI: 10.1128/Jb.01135-09 |
0.358 |
|
| 2010 |
Mosser R, Reddy M, Bruning J, Sacchettini JC, Reinhart GD. Redefining the Role of the Quaternary Shift in the Allosteric Inhibition of Bacillus Stearothermophilus Phosphofructokinase Biophysical Journal. 98: 39a. DOI: 10.1016/J.Bpj.2009.12.226 |
0.385 |
|
| 2009 |
Musa TL, Ioerger TR, Sacchettini JC. The tuberculosis structural genomics consortium: a structural genomics approach to drug discovery. Advances in Protein Chemistry and Structural Biology. 77: 41-76. PMID 20663481 DOI: 10.1016/S1876-1623(09)77003-8 |
0.403 |
|
| 2009 |
Ioerger TR, Koo S, No EG, Chen X, Larsen MH, Jacobs WR, Pillay M, Sturm AW, Sacchettini JC. Genome analysis of multi- and extensively-drug-resistant tuberculosis from KwaZulu-Natal, South Africa. Plos One. 4: e7778. PMID 19890396 DOI: 10.1371/Journal.Pone.0007778 |
0.321 |
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| 2009 |
Reddy MC, Palaninathan SK, Bruning JB, Thurman C, Smith D, Sacchettini JC. Structural insights into the mechanism of the allosteric transitions of Mycobacterium tuberculosis cAMP receptor protein. The Journal of Biological Chemistry. 284: 36581-91. PMID 19740754 DOI: 10.1074/Jbc.M109.041343 |
0.38 |
|
| 2009 |
Palaninathan SK, Mohamedmohaideen NN, Orlandini E, Ortore G, Nencetti S, Lapucci A, Rossello A, Freundlich JS, Sacchettini JC. Novel transthyretin amyloid fibril formation inhibitors: synthesis, biological evaluation, and X-ray structural analysis. Plos One. 4: e6290. PMID 19621084 DOI: 10.1371/Journal.Pone.0006290 |
0.4 |
|
| 2009 |
Swanson S, Gokulan K, Sacchettini JC. KasA, another brick in the mycobacterial cell wall. Structure (London, England : 1993). 17: 914-5. PMID 19604470 DOI: 10.1016/J.Str.2009.06.006 |
0.331 |
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| 2009 |
Payne K, Sun Q, Sacchettini J, Hatfull GF. Mycobacteriophage Lysin B is a novel mycolylarabinogalactan esterase. Molecular Microbiology. 73: 367-81. PMID 19555454 DOI: 10.1111/J.1365-2958.2009.06775.X |
0.34 |
|
| 2009 |
Ioerger TR, Sacchettini JC. Structural genomics approach to drug discovery for Mycobacterium tuberculosis. Current Opinion in Microbiology. 12: 318-25. PMID 19481971 DOI: 10.1016/J.Mib.2009.04.006 |
0.421 |
|
| 2009 |
Barkan D, Liu Z, Sacchettini JC, Glickman MS. Mycolic acid cyclopropanation is essential for viability, drug resistance, and cell wall integrity of Mycobacterium tuberculosis. Chemistry & Biology. 16: 499-509. PMID 19477414 DOI: 10.1016/J.Chembiol.2009.04.001 |
0.399 |
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| 2009 |
Freundlich JS, Wang F, Vilchèze C, Gulten G, Langley R, Schiehser GA, Jacobus DP, Jacobs WR, Sacchettini JC. Triclosan derivatives: towards potent inhibitors of drug-sensitive and drug-resistant Mycobacterium tuberculosis. Chemmedchem. 4: 241-8. PMID 19130456 DOI: 10.1002/Cmdc.200800261 |
0.457 |
|
| 2009 |
Mosser R, Reddy M, Sacchettini JC, Igumenova T, Reinhart GD. A Solution NMR and Crystallographic Study of the Role of the Quaternary Shift in the Allosteric Regulation of Phosphofructokinase from B. stearothermophilus Biophysical Journal. 96: 5a. DOI: 10.1016/J.Bpj.2008.12.917 |
0.392 |
|
| 2008 |
Reddy MC, Kuppan G, Shetty ND, Owen JL, Ioerger TR, Sacchettini JC. Crystal structures of Mycobacterium tuberculosis S-adenosyl-L-homocysteine hydrolase in ternary complex with substrate and inhibitors. Protein Science : a Publication of the Protein Society. 17: 2134-44. PMID 18815415 DOI: 10.1110/Ps.038125.108 |
0.435 |
|
| 2008 |
Cho Y, Ioerger TR, Sacchettini JC. Discovery of novel nitrobenzothiazole inhibitors for Mycobacterium tuberculosis ATP phosphoribosyl transferase (HisG) through virtual screening. Journal of Medicinal Chemistry. 51: 5984-92. PMID 18778048 DOI: 10.1021/Jm800328V |
0.426 |
|
| 2008 |
Palaninathan SK, Mohamedmohaideen NN, Snee WC, Kelly JW, Sacchettini JC. Structural insight into pH-induced conformational changes within the native human transthyretin tetramer. Journal of Molecular Biology. 382: 1157-67. PMID 18662699 DOI: 10.1016/J.Jmb.2008.07.029 |
0.356 |
|
| 2008 |
Vilchèze C, Av-Gay Y, Attarian R, Liu Z, Hazbón MH, Colangeli R, Chen B, Liu W, Alland D, Sacchettini JC, Jacobs WR. Mycothiol biosynthesis is essential for ethionamide susceptibility in Mycobacterium tuberculosis. Molecular Microbiology. 69: 1316-29. PMID 18651841 DOI: 10.1111/J.1365-2958.2008.06365.X |
0.357 |
|
| 2008 |
Dey S, Burton RL, Grant GA, Sacchettini JC. Structural analysis of substrate and effector binding in Mycobacterium tuberculosis D-3-phosphoglycerate dehydrogenase. Biochemistry. 47: 8271-82. PMID 18627175 DOI: 10.1021/Bi800212B |
0.629 |
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| 2008 |
Javid-Majd F, Yang D, Ioerger TR, Sacchettini JC. The 1.25 A resolution structure of phosphoribosyl-ATP pyrophosphohydrolase from Mycobacterium tuberculosis. Acta Crystallographica. Section D, Biological Crystallography. 64: 627-35. PMID 18560150 DOI: 10.1107/S0907444908007105 |
0.459 |
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| 2008 |
Zwart PH, Afonine PV, Grosse-Kunstleve RW, Hung LW, Ioerger TR, McCoy AJ, McKee E, Moriarty NW, Read RJ, Sacchettini JC, Sauter NK, Storoni LC, Terwilliger TC, Adams PD. Automated structure solution with the PHENIX suite. Methods in Molecular Biology (Clifton, N.J.). 426: 419-35. PMID 18542881 DOI: 10.1007/978-1-60327-058-8_28 |
0.314 |
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| 2008 |
Mohamedmohaideen NN, Palaninathan SK, Morin PM, Williams BJ, Braunstein M, Tichy SE, Locker J, Russell DH, Jacobs WR, Sacchettini JC. Structure and function of the virulence-associated high-temperature requirement A of Mycobacterium tuberculosis. Biochemistry. 47: 6092-102. PMID 18479146 DOI: 10.1021/Bi701929M |
0.409 |
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| 2008 |
Sacchettini JC, Rubin EJ, Freundlich JS. Drugs versus bugs: in pursuit of the persistent predator Mycobacterium tuberculosis. Nature Reviews. Microbiology. 6: 41-52. PMID 18079742 DOI: 10.1038/Nrmicro1816 |
0.328 |
|
| 2008 |
Bhardwaj K, Palaninathan S, Alcantara JM, Yi LL, Guarino L, Sacchettini JC, Kao CC. Structural and functional analyses of the severe acute respiratory syndrome coronavirus endoribonuclease Nsp15. The Journal of Biological Chemistry. 283: 3655-64. PMID 18045871 DOI: 10.1074/Jbc.M708375200 |
0.32 |
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| 2008 |
Reddy MC, Gokulan K, Jacobs WR, Ioerger TR, Sacchettini JC. Crystal structure of Mycobacterium tuberculosis LrpA, a leucine-responsive global regulator associated with starvation response. Protein Science : a Publication of the Protein Society. 17: 159-70. PMID 18042675 DOI: 10.1110/Ps.073192208 |
0.436 |
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| 2008 |
Miesel L, Rozwarski DA, Sacchettini JC, Jacobs WR. Mechanisms for isoniazid action and resistance. Novartis Foundation Symposium. 217: 209-221. PMID 9949810 DOI: 10.1002/0470846526.Ch15 |
0.392 |
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| 2008 |
Giddens AC, Nielsen L, Boshoff HI, Tasdemir D, Perozzo R, Kaiser M, Wang F, Sacchettini JC, Copp BR. Natural product inhibitors of fatty acid biosynthesis: synthesis of the marine microbial metabolites pseudopyronines A and B and evaluation of their anti-infective activities Tetrahedron. 64: 1242-1249. DOI: 10.1016/J.Tet.2007.11.075 |
0.36 |
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| 2007 |
Alahari A, Trivelli X, Guérardel Y, Dover LG, Besra GS, Sacchettini JC, Reynolds RC, Coxon GD, Kremer L. Thiacetazone, an antitubercular drug that inhibits cyclopropanation of cell wall mycolic acids in mycobacteria. Plos One. 2: e1343. PMID 18094751 DOI: 10.1371/Journal.Pone.0001343 |
0.358 |
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| 2007 |
Murillo AC, Li HY, Alber T, Baker EN, Berger JM, Cherney LT, Cherney MM, Cho YS, Eisenberg D, Garen CR, Goulding CW, Hung LW, Ioerger TR, Jacobs WR, James MN, ... ... Sacchettini JC, et al. High throughput crystallography of TB drug targets. Infectious Disorders Drug Targets. 7: 127-39. PMID 17970224 DOI: 10.2174/187152607781001853 |
0.405 |
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| 2007 |
Reddy MC, Palaninathan SK, Shetty ND, Owen JL, Watson MD, Sacchettini JC. High resolution crystal structures of Mycobacterium tuberculosis adenosine kinase: insights into the mechanism and specificity of this novel prokaryotic enzyme. The Journal of Biological Chemistry. 282: 27334-42. PMID 17597075 DOI: 10.1074/Jbc.M703290200 |
0.448 |
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| 2007 |
Freundlich JS, Wang F, Tsai HC, Kuo M, Shieh HM, Anderson JW, Nkrumah LJ, Valderramos JC, Yu M, Kumar TR, Valderramos SG, Jacobs WR, Schiehser GA, Jacobus DP, Fidock DA, ... Sacchettini JC, et al. X-ray structural analysis of Plasmodium falciparum enoyl acyl carrier protein reductase as a pathway toward the optimization of triclosan antimalarial efficacy. The Journal of Biological Chemistry. 282: 25436-44. PMID 17567585 DOI: 10.1074/Jbc.M701813200 |
0.811 |
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| 2007 |
Tsai CL, Gokulan K, Sobrado P, Sacchettini JC, Fitzpatrick PF. Mechanistic and structural studies of H373Q flavocytochrome b2: effects of mutating the active site base. Biochemistry. 46: 7844-51. PMID 17563122 DOI: 10.1021/Bi7005543 |
0.363 |
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| 2007 |
Cai X, Lorraine Fuller A, McDougald LR, Tan X, Cai J, Wang F, Sacchettini JC, Zhu G. Biochemical characterization of enoyl reductase involved in Type II fatty acid synthesis in the intestinal coccidium Eimeria tenella (Phylum Apicomplexa). Fems Microbiology Letters. 272: 238-44. PMID 17559403 DOI: 10.1111/J.1574-6968.2007.00767.X |
0.371 |
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| 2007 |
Wang F, Langley R, Gulten G, Wang L, Sacchettini JC. Identification of a type III thioesterase reveals the function of an operon crucial for Mtb virulence. Chemistry & Biology. 14: 543-51. PMID 17524985 DOI: 10.1016/J.Chembiol.2007.04.005 |
0.427 |
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| 2007 |
Nicola G, Smith CA, Lucumi E, Kuo MR, Karagyozov L, Fidock DA, Sacchettini JC, Abagyan R. Discovery of novel inhibitors targeting enoyl-acyl carrier protein reductase in Plasmodium falciparum by structure-based virtual screening. Biochemical and Biophysical Research Communications. 358: 686-91. PMID 17509532 DOI: 10.1016/J.Bbrc.2007.04.113 |
0.802 |
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| 2007 |
Dey S, Hu Z, Xu XL, Sacchettini JC, Grant GA. The effect of hinge mutations on effector binding and domain rotation in Escherichia coli D-3-phosphoglycerate dehydrogenase. The Journal of Biological Chemistry. 282: 18418-26. PMID 17459882 DOI: 10.1074/Jbc.M701174200 |
0.602 |
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| 2007 |
Ramesh A, Savva CG, Holzenburg A, Sacchettini JC. Crystal structure of Rsr, an ortholog of the antigenic Ro protein, links conformational flexibility to RNA binding activity. The Journal of Biological Chemistry. 282: 14960-7. PMID 17392270 DOI: 10.1074/Jbc.M611163200 |
0.547 |
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| 2007 |
Wang F, Langley R, Gulten G, Dover LG, Besra GS, Jacobs WR, Sacchettini JC. Mechanism of thioamide drug action against tuberculosis and leprosy. The Journal of Experimental Medicine. 204: 73-8. PMID 17227913 DOI: 10.1084/Jem.20062100 |
0.381 |
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| 2007 |
Sridharan S, Wang L, Brown AK, Dover LG, Kremer L, Besra GS, Sacchettini JC. X-ray crystal structure of Mycobacterium tuberculosis beta-ketoacyl acyl carrier protein synthase II (mtKasB). Journal of Molecular Biology. 366: 469-80. PMID 17174327 DOI: 10.1016/J.Jmb.2006.11.006 |
0.466 |
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| 2007 |
Liu T, Ramesh A, Ma Z, Ward SK, Zhang L, George GN, Talaat AM, Sacchettini JC, Giedroc DP. CsoR is a novel Mycobacterium tuberculosis copper-sensing transcriptional regulator. Nature Chemical Biology. 3: 60-8. PMID 17143269 DOI: 10.1038/Nchembio844 |
0.56 |
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| 2007 |
Gopal K, McKee E, Romo T, Pai R, Smith J, Sacchettini J, Ioerger T. Crystallographic protein model-building on the web. Bioinformatics (Oxford, England). 23: 375-7. PMID 17138588 DOI: 10.1093/Bioinformatics/Btl584 |
0.307 |
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| 2007 |
Sidhu AB, Sun Q, Nkrumah LJ, Dunne MW, Sacchettini JC, Fidock DA. In vitro efficacy, resistance selection, and structural modeling studies implicate the malarial parasite apicoplast as the target of azithromycin. The Journal of Biological Chemistry. 282: 2494-504. PMID 17110371 DOI: 10.1074/Jbc.M608615200 |
0.354 |
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| 2006 |
Vilchèze C, Wang F, Arai M, Hazbón MH, Colangeli R, Kremer L, Weisbrod TR, Alland D, Sacchettini JC, Jacobs WR. Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid. Nature Medicine. 12: 1027-9. PMID 16906155 DOI: 10.1038/Nm1466 |
0.388 |
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| 2006 |
Gould TA, van de Langemheen H, Muñoz-Elías EJ, McKinney JD, Sacchettini JC. Dual role of isocitrate lyase 1 in the glyoxylate and methylcitrate cycles in Mycobacterium tuberculosis. Molecular Microbiology. 61: 940-7. PMID 16879647 DOI: 10.1111/J.1365-2958.2006.05297.X |
0.437 |
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| 2006 |
Wang F, Cassidy C, Sacchettini JC. Crystal structure and activity studies of the Mycobacterium tuberculosis beta-lactamase reveal its critical role in resistance to beta-lactam antibiotics. Antimicrobial Agents and Chemotherapy. 50: 2762-71. PMID 16870770 DOI: 10.1128/Aac.00320-06 |
0.407 |
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| 2006 |
Owens RM, Hsu FF, VanderVen BC, Purdy GE, Hesteande E, Giannakas P, Sacchettini JC, McKinney JD, Hill PJ, Belisle JT, Butcher BA, Pethe K, Russell DG. M. tuberculosis Rv2252 encodes a diacylglycerol kinase involved in the biosynthesis of phosphatidylinositol mannosides (PIMs). Molecular Microbiology. 60: 1152-63. PMID 16689792 DOI: 10.1111/J.1365-2958.2006.05174.X |
0.345 |
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| 2006 |
Zhao X, Yu H, Yu S, Wang F, Sacchettini JC, Magliozzo RS. Hydrogen peroxide-mediated isoniazid activation catalyzed by Mycobacterium tuberculosis catalase-peroxidase (KatG) and its S315T mutant. Biochemistry. 45: 4131-40. PMID 16566587 DOI: 10.1021/Bi051967O |
0.436 |
|
| 2006 |
Freundlich JS, Yu M, Lucumi E, Kuo M, Tsai HC, Valderramos JC, Karagyozov L, Jacobs WR, Schiehser GA, Fidock DA, Jacobus DP, Sacchettini JC. Synthesis and biological activity of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 2: 2'-substituted triclosan derivatives. Bioorganic & Medicinal Chemistry Letters. 16: 2163-9. PMID 16466916 DOI: 10.1016/J.Bmcl.2006.01.051 |
0.799 |
|
| 2006 |
Freundlich JS, Anderson JW, Sarantakis D, Shieh H, Yu M, Valderramos J, Lucumi E, Kuo M, Jacobs WR, Fidock DA, Schiehser GA, Jacobus DP, Sacchettini JC. Erratum to “Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4′-Substituted triclosan derivatives” [Bioorg. Med. Chem. Lett. 15 (2005) 5247–5252] Bioorganic & Medicinal Chemistry Letters. 16: 3618-3619. DOI: 10.1016/J.Bmcl.2005.12.054 |
0.795 |
|
| 2005 |
Paricharttanakul NM, Ye S, Menefee AL, Javid-Majd F, Sacchettini JC, Reinhart GD. Kinetic and structural characterization of phosphofructokinase from Lactobacillus bulgaricus. Biochemistry. 44: 15280-6. PMID 16285731 DOI: 10.1021/Bi051283G |
0.386 |
|
| 2005 |
Bhatt A, Kremer L, Dai AZ, Sacchettini JC, Jacobs WR. Conditional depletion of KasA, a key enzyme of mycolic acid biosynthesis, leads to mycobacterial cell lysis. Journal of Bacteriology. 187: 7596-606. PMID 16267284 DOI: 10.1128/Jb.187.22.7596-7606.2005 |
0.39 |
|
| 2005 |
Freundlich JS, Anderson JW, Sarantakis D, Shieh HM, Yu M, Valderramos JC, Lucumi E, Kuo M, Jacobs WR, Fidock DA, Schiehser GA, Jacobus DP, Sacchettini JC. Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4'-substituted triclosan derivatives. Bioorganic & Medicinal Chemistry Letters. 15: 5247-52. PMID 16198563 DOI: 10.1016/J.Bmcl.2005.08.044 |
0.818 |
|
| 2005 |
Brown AK, Sridharan S, Kremer L, Lindenberg S, Dover LG, Sacchettini JC, Besra GS. Probing the mechanism of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III mtFabH: factors influencing catalysis and substrate specificity. The Journal of Biological Chemistry. 280: 32539-47. PMID 16040614 DOI: 10.1074/Jbc.M413216200 |
0.392 |
|
| 2005 |
Gokulan K, Khare S, Ronning DR, Linthicum SD, Sacchettini JC, Rupp B. Cocrystal structures of NC6.8 Fab identify key interactions for high potency sweetener recognition: implications for the design of synthetic sweeteners. Biochemistry. 44: 9889-98. PMID 16026161 DOI: 10.1021/Bi050613U |
0.674 |
|
| 2005 |
Colangeli R, Helb D, Sridharan S, Sun J, Varma-Basil M, Hazbón MH, Harbacheuski R, Megjugorac NJ, Jacobs WR, Holzenburg A, Sacchettini JC, Alland D. The Mycobacterium tuberculosis iniA gene is essential for activity of an efflux pump that confers drug tolerance to both isoniazid and ethambutol. Molecular Microbiology. 55: 1829-40. PMID 15752203 DOI: 10.1111/J.1365-2958.2005.04510.X |
0.394 |
|
| 2005 |
Johnson SM, Petrassi HM, Palaninathan SK, Mohamedmohaideen NN, Purkey HE, Nichols C, Chiang KP, Walkup T, Sacchettini JC, Sharpless KB, Kelly JW. Bisaryloxime ethers as potent inhibitors of transthyretin amyloid fibril formation. Journal of Medicinal Chemistry. 48: 1576-87. PMID 15743199 DOI: 10.1021/Jm049274D |
0.349 |
|
| 2005 |
Sridharan S, Razvi A, Scholtz JM, Sacchettini JC. The HPr proteins from the thermophile Bacillus stearothermophilus can form domain-swapped dimers. Journal of Molecular Biology. 346: 919-31. PMID 15713472 DOI: 10.1016/J.Jmb.2004.12.008 |
0.364 |
|
| 2005 |
Vilchèze C, Weisbrod TR, Chen B, Kremer L, Hazbón MH, Wang F, Alland D, Sacchettini JC, Jacobs WR. Altered NADH/NAD+ ratio mediates coresistance to isoniazid and ethionamide in mycobacteria. Antimicrobial Agents and Chemotherapy. 49: 708-20. PMID 15673755 DOI: 10.1128/Aac.49.2.708-720.2005 |
0.368 |
|
| 2005 |
Dey S, Hu Z, Xu XL, Sacchettini JC, Grant GA. D-3-Phosphoglycerate dehydrogenase from Mycobacterium tuberculosis is a link between the Escherichia coli and mammalian enzymes. The Journal of Biological Chemistry. 280: 14884-91. PMID 15668250 DOI: 10.1074/Jbc.M414488200 |
0.628 |
|
| 2005 |
Dey S, Grant GA, Sacchettini JC. Crystal structure of Mycobacterium tuberculosis D-3-phosphoglycerate dehydrogenase: extreme asymmetry in a tetramer of identical subunits. The Journal of Biological Chemistry. 280: 14892-9. PMID 15668249 DOI: 10.1074/Jbc.M414489200 |
0.614 |
|
| 2005 |
Lee JE, Kim K, Sacchettini JC, Smith CV, Safe S. DRIP150 coactivation of estrogen receptor alpha in ZR-75 breast cancer cells is independent of LXXLL motifs. The Journal of Biological Chemistry. 280: 8819-30. PMID 15625066 DOI: 10.1074/Jbc.M413184200 |
0.313 |
|
| 2005 |
Romo T, Gopal K, McKee E, Kanbi L, Pai R, Smith J, Sacchettini J, Ioerger T. TEXTAL: Al-based structural determination for X-ray protein crystallography Ieee Intelligent Systems. 20: 59-63. DOI: 10.1109/Mis.2005.114 |
0.375 |
|
| 2004 |
Purkey HE, Palaninathan SK, Kent KC, Smith C, Safe SH, Sacchettini JC, Kelly JW. Hydroxylated polychlorinated biphenyls selectively bind transthyretin in blood and inhibit amyloidogenesis: rationalizing rodent PCB toxicity. Chemistry & Biology. 11: 1719-28. PMID 15610856 DOI: 10.1016/J.Chembiol.2004.10.009 |
0.305 |
|
| 2004 |
Ronning DR, Vissa V, Besra GS, Belisle JT, Sacchettini JC. Mycobacterium tuberculosis antigen 85A and 85C structures confirm binding orientation and conserved substrate specificity. The Journal of Biological Chemistry. 279: 36771-7. PMID 15192106 DOI: 10.1074/Jbc.M400811200 |
0.708 |
|
| 2004 |
Ye S, Vakonakis I, Ioerger TR, LiWang AC, Sacchettini JC. Crystal structure of circadian clock protein KaiA from Synechococcus elongatus. The Journal of Biological Chemistry. 279: 20511-8. PMID 15007067 DOI: 10.1074/Jbc.M400077200 |
0.387 |
|
| 2004 |
Adamski-Werner SL, Palaninathan SK, Sacchettini JC, Kelly JW. Diflunisal analogues stabilize the native state of transthyretin. Potent inhibition of amyloidogenesis. Journal of Medicinal Chemistry. 47: 355-74. PMID 14711308 DOI: 10.1021/Jm030347N |
0.394 |
|
| 2004 |
Smith CV, Sharma V, Sacchettini JC. TB drug discovery: addressing issues of persistence and resistance. Tuberculosis (Edinburgh, Scotland). 84: 45-55. PMID 14670345 DOI: 10.1016/J.Tube.2003.08.019 |
0.397 |
|
| 2003 |
Smith CV, Sacchettini JC. Mycobacterium tuberculosis: a model system for structural genomics. Current Opinion in Structural Biology. 13: 658-64. PMID 14675542 DOI: 10.1016/J.Sbi.2003.10.004 |
0.399 |
|
| 2003 |
Green NS, Palaninathan SK, Sacchettini JC, Kelly JW. Synthesis and characterization of potent bivalent amyloidosis inhibitors that bind prior to transthyretin tetramerization. Journal of the American Chemical Society. 125: 13404-14. PMID 14583036 DOI: 10.1021/Ja030294Z |
0.386 |
|
| 2003 |
Eicken C, Pennella MA, Chen X, Koshlap KM, VanZile ML, Sacchettini JC, Giedroc DP. A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins. Journal of Molecular Biology. 333: 683-95. PMID 14568530 DOI: 10.1016/J.Jmb.2003.09.007 |
0.31 |
|
| 2003 |
Terwilliger TC, Park MS, Waldo GS, Berendzen J, Hung LW, Kim CY, Smith CV, Sacchettini JC, Bellinzoni M, Bossi R, De Rossi E, Mattevi A, Milano A, Riccardi G, Rizzi M, et al. The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology. Tuberculosis (Edinburgh, Scotland). 83: 223-49. PMID 12906835 DOI: 10.1016/S1472-9792(03)00051-9 |
0.402 |
|
| 2003 |
Zhang F, Lücke C, Baier LJ, Sacchettini JC, Hamilton JA. Solution structure of human intestinal fatty acid binding protein with a naturally-occurring single amino acid substitution (A54T) that is associated with altered lipid metabolism. Biochemistry. 42: 7339-47. PMID 12809489 DOI: 10.1021/Bi0273617 |
0.377 |
|
| 2003 |
Kremer L, Dover LG, Morbidoni HR, Vilchèze C, Maughan WN, Baulard A, Tu SC, Honoré N, Deretic V, Sacchettini JC, Locht C, Jacobs WR, Besra GS. Inhibition of InhA activity, but not KasA activity, induces formation of a KasA-containing complex in mycobacteria. The Journal of Biological Chemistry. 278: 20547-54. PMID 12654922 DOI: 10.1074/Jbc.M302435200 |
0.352 |
|
| 2003 |
Gokulan K, Rupp B, Pavelka MS, Jacobs WR, Sacchettini JC. Crystal structure of Mycobacterium tuberculosis diaminopimelate decarboxylase, an essential enzyme in bacterial lysine biosynthesis. The Journal of Biological Chemistry. 278: 18588-96. PMID 12637582 DOI: 10.1074/Jbc.M301549200 |
0.478 |
|
| 2003 |
Sharma V, Arockiasamy A, Ronning DR, Savva CG, Holzenburg A, Braunstein M, Jacobs WR, Sacchettini JC. Crystal structure of Mycobacterium tuberculosis SecA, a preprotein translocating ATPase. Proceedings of the National Academy of Sciences of the United States of America. 100: 2243-8. PMID 12606717 DOI: 10.1073/Pnas.0538077100 |
0.691 |
|
| 2003 |
Kuo MR, Morbidoni HR, Alland D, Sneddon SF, Gourlie BB, Staveski MM, Leonard M, Gregory JS, Janjigian AD, Yee C, Musser JM, Kreiswirth B, Iwamoto H, Perozzo R, Jacobs WR, ... Sacchettini JC, et al. Targeting tuberculosis and malaria through inhibition of Enoyl reductase: compound activity and structural data. The Journal of Biological Chemistry. 278: 20851-9. PMID 12606558 DOI: 10.1074/Jbc.M211968200 |
0.823 |
|
| 2003 |
Cho Y, Sharma V, Sacchettini JC. Crystal structure of ATP phosphoribosyltransferase from Mycobacterium tuberculosis. Journal of Biological Chemistry. 278: 8333-8339. PMID 12511575 DOI: 10.1074/Jbc.M212124200 |
0.456 |
|
| 2003 |
Smith CV, Huang CC, Miczak A, Russell DG, Sacchettini JC, Höner zu Bentrup K. Biochemical and structural studies of malate synthase from Mycobacterium tuberculosis. The Journal of Biological Chemistry. 278: 1735-43. PMID 12393860 DOI: 10.1074/Jbc.M209248200 |
0.426 |
|
| 2003 |
Perozzo R, Kuo M, Sidhu AS, Valiyaveettil JT, Bittman R, WRJJ, Fidock DA, Sacchettini JC. Structural Elucidation of the Specificity of the Antibacterial Agent Triclosan for Malarial Enoyl Acyl Carrier Protein Reductase Year Journal of Biological Chemistry. 277: 13106-13114. DOI: 10.2210/Pdb1Nhw/Pdb |
0.788 |
|
| 2003 |
Sun J, Sridharan S, Sacchettini J, Savva C, Holzenburg A. TEM Studies of IniA from Mycobacterium tuberculosis Microscopy and Microanalysis. 9: 1418-1419. DOI: 10.1017/S1431927603447090 |
0.317 |
|
| 2002 |
Goulding CW, Apostol M, Anderson DH, Gill HS, Smith CV, Kuo MR, Yang JK, Waldo GS, Suh SW, Chauhan R, Kale A, Bachhawat N, Mande SC, Johnston JM, Lott JS, ... ... Sacchettini J, et al. The TB structural genomics consortium: providing a structural foundation for drug discovery. Current Drug Targets. Infectious Disorders. 2: 121-41. PMID 12462144 DOI: 10.2174/1568005023342551 |
0.803 |
|
| 2002 |
Larsen MH, Vilchèze C, Kremer L, Besra GS, Parsons L, Salfinger M, Heifets L, Hazbon MH, Alland D, Sacchettini JC, Jacobs WR. Overexpression of inhA, but not kasA, confers resistance to isoniazid and ethionamide in Mycobacterium smegmatis, M. bovis BCG and M. tuberculosis Molecular Microbiology. 46: 453-466. PMID 12406221 DOI: 10.1046/J.1365-2958.2002.03162.X |
0.322 |
|
| 2002 |
Adams PD, Grosse-Kunstleve RW, Hung LW, Ioerger TR, McCoy AJ, Moriarty NW, Read RJ, Sacchettini JC, Sauter NK, Terwilliger TC. PHENIX: building new software for automated crystallographic structure determination. Acta Crystallographica. Section D, Biological Crystallography. 58: 1948-54. PMID 12393927 DOI: 10.1107/S0907444902016657 |
0.33 |
|
| 2002 |
Riley-Lovingshimer MR, Ronning DR, Sacchettini JC, Reinhart GD. Reversible ligand-induced dissociation of a tryptophan-shift mutant of phosphofructokinase from Bacillus stearothermophilus. Biochemistry. 41: 12967-74. PMID 12390023 DOI: 10.1021/Bi0263412 |
0.688 |
|
| 2002 |
Eicken C, Sharma V, Klabunde T, Lawrenz MB, Hardham JM, Norris SJ, Sacchettini JC. Crystal structure of Lyme disease variable surface antigen VlsE of Borrelia burgdorferi. The Journal of Biological Chemistry. 277: 21691-6. PMID 11923306 DOI: 10.1074/Jbc.M201547200 |
0.319 |
|
| 2002 |
Perozzo R, Kuo M, Sidhu ABS, Valiyaveettil JT, Bittman R, Jacobs WR, Fidock DA, Sacchettini JC. Structural elucidation of the specificity of the antibacterial agent triclosan for malarial enoyl acyl carrier protein reductase Journal of Biological Chemistry. 277: 13106-13114. PMID 11792710 DOI: 10.1074/Jbc.M112000200 |
0.82 |
|
| 2002 |
Huang CC, Smith CV, Glickman MS, Jacobs WR, Sacchettini JC. Crystal structures of mycolic acid cyclopropane synthases from Mycobacterium tuberculosis. The Journal of Biological Chemistry. 277: 11559-69. PMID 11756461 DOI: 10.1074/Jbc.M111698200 |
0.47 |
|
| 2002 |
Yang D, Shipman LW, Roessner CA, Scott AI, Sacchettini JC. Structure of the Methanococcus jannaschii mevalonate kinase, a member of the GHMP kinase superfamily. The Journal of Biological Chemistry. 277: 9462-7. PMID 11751891 DOI: 10.1074/Jbc.M110787200 |
0.792 |
|
| 2001 |
Jiang X, Smith CS, Petrassi HM, Hammarström P, White JT, Sacchettini JC, Kelly JW. An engineered transthyretin monomer that is nonamyloidogenic, unless it is partially denatured. Biochemistry. 40: 11442-52. PMID 11560492 DOI: 10.1021/Bi011194D |
0.367 |
|
| 2001 |
Shipman LW, Li D, Roessner CA, Scott AI, Sacchettini JC. Crystal structure of precorrin-8x methyl mutase. Structure (London, England : 1993). 9: 587-96. PMID 11470433 DOI: 10.1016/S0969-2126(01)00618-9 |
0.774 |
|
| 2001 |
Eicken C, Sharma V, Klabunde T, Owens RT, Pikas DS, Höök M, Sacchettini JC. Crystal Structure of Lyme Disease Antigen Outer Surface Protein C from Borrelia burgdorferi Journal of Biological Chemistry. 276: 10010-10015. PMID 11139584 DOI: 10.1074/Jbc.M010062200 |
0.331 |
|
| 2000 |
Sacchettini JC, Ronning DR. The mycobacterial antigens 85 complex--from structure to function: response. Trends in Microbiology. 8: 441. PMID 11203233 DOI: 10.1016/S0966-842X(00)01843-6 |
0.685 |
|
| 2000 |
McKinney JD, Höner zu Bentrup K, Muñoz-Elías EJ, Miczak A, Chen B, Chan WT, Swenson D, Sacchettini JC, Jacobs WR, Russell DG. Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase. Nature. 406: 735-8. PMID 10963599 DOI: 10.1038/35021074 |
0.327 |
|
| 2000 |
Sharma V, Sharma S, Hoener zu Bentrup K, McKinney JD, Russell DG, Jacobs WR, Sacchettini JC. Structure of isocitrate lyase, a persistence factor of Mycobacterium tuberculosis. Nature Structural Biology. 7: 663-8. PMID 10932251 DOI: 10.1038/77964 |
0.449 |
|
| 2000 |
Vilchèze C, Morbidoni HR, Weisbrod TR, Iwamoto H, Kuo M, Sacchettini JC, Jacobs WR. Inactivation of the inhA-encoded fatty acid synthase II (FASII) enoyl-acyl carrier protein reductase induces accumulation of the FASI end products and cell lysis of Mycobacterium smegmatis. Journal of Bacteriology. 182: 4059-4067. PMID 10869086 DOI: 10.1128/Jb.182.14.4059-4067.2000 |
0.785 |
|
| 2000 |
Balendiran GK, Schnutgen F, Scapin G, Borchers T, Xhong N, Lim K, Godbout R, Spener F, Sacchettini JC. Crystal structure and thermodynamic analysis of human brain fatty acid-binding protein. The Journal of Biological Chemistry. 275: 27045-54. PMID 10854433 DOI: 10.1074/Jbc.M003001200 |
0.315 |
|
| 2000 |
Holton T, Ioerger TR, Christopher JA, Sacchettini JC. Determining protein structure from electron-density maps using pattern matching Acta Crystallographica Section D: Biological Crystallography. 56: 722-734. PMID 10818349 DOI: 10.1107/S0907444900003450 |
0.31 |
|
| 2000 |
Lücke C, Zhang F, Hamilton JA, Sacchettini JC, Rüterjans H. Solution structure of ileal lipid binding protein in complex with glycocholate. European Journal of Biochemistry. 267: 2929-38. PMID 10806391 DOI: 10.1046/J.1432-1327.2000.01307.X |
0.393 |
|
| 2000 |
Klabunde T, Petrassi HM, Oza VB, Raman P, Kelly JW, Sacchettini JC. Rational design of potent human transthyretin amyloid disease inhibitors. Nature Structural Biology. 7: 312-21. PMID 10742177 DOI: 10.1038/74082 |
0.365 |
|
| 2000 |
Wolfrum C, Börchers T, Sacchettini JC, Spener F. Binding of fatty acids and peroxisome proliferators to orthologous fatty acid binding proteins from human, murine, and bovine liver. Biochemistry. 39: 14363-14363. PMID 10684629 DOI: 10.1021/Bi991638U |
0.32 |
|
| 2000 |
Ronning DR, Klabunde T, Besra GS, Vissa VD, Belisle JT, Sacchettini JC. Crystal structure of the secreted form of antigen 85C reveals potential targets for mycobacterial drugs and vaccines. Nature Structural Biology. 7: 141-6. PMID 10655617 DOI: 10.1038/72413 |
0.72 |
|
| 2000 |
O'Hagan RC, Schreiber-Agus N, Chen K, David G, Engelman JA, Schwab R, Alland L, Thomson C, Ronning DR, Sacchettini JC, Meltzer P, DePinho RA. Gene-target recognition among members of the myc superfamily and implications for oncogenesis. Nature Genetics. 24: 113-9. PMID 10655054 DOI: 10.1038/72761 |
0.646 |
|
| 1999 |
Eicken C, Krebs B, Sacchettini JC. Catechol oxidase - structure and activity. Current Opinion in Structural Biology. 9: 677-83. PMID 10607672 DOI: 10.1016/S0959-440X(99)00029-9 |
0.389 |
|
| 1999 |
Kurokawa H, Dewan JC, Mikami B, Sacchettini JC, Hirose M. Crystal structure of hen apo-ovotransferrin. Both lobes adopt an open conformation upon loss of iron. Journal of Biological Chemistry. 274: 28445-28452. PMID 10497206 DOI: 10.1074/Jbc.274.40.28445 |
0.309 |
|
| 1999 |
Balendiran GK, Molina JA, Xu Y, Torres-Martinez J, Stevens R, Focia PJ, Eakin AE, Sacchettini JC, Craig SP. Ternary complex structure of human HGPRTase, PRPP, Mg2+, and the inhibitor HPP reveals the involvement of the flexible loop in substrate binding. Protein Science : a Publication of the Protein Society. 8: 1023-31. PMID 10338013 DOI: 10.1110/Ps.8.5.1023 |
0.403 |
|
| 1999 |
Rozwarski DA, Vilchèze C, Sugantino M, Bittman R, Sacchettini JC. Crystal structure of the Mycobacterium tuberculosis enoyl-ACP reductase, InhA, in complex with NAD+ and a C16 fatty acyl substrate. The Journal of Biological Chemistry. 274: 15582-9. PMID 10336454 DOI: 10.1074/Jbc.274.22.15582 |
0.395 |
|
| 1999 |
Lücke C, Fushman D, Ludwig C, Hamilton JA, Sacchettini JC, Rüterjans H. A comparative study of the backbone dynamics of two closely related lipid binding proteins: bovine heart fatty acid binding protein and porcine ileal lipid binding protein. Molecular and Cellular Biochemistry. 192: 109-21. PMID 10331665 DOI: 10.1023/A:1006834708786 |
0.355 |
|
| 1999 |
O'Hagan R, Schreiber-Agus N, Engelman JA, Schwab R, Alland L, Thompson C, Ronning DR, Sacchettini JC, Meltzer P, DePinho RA. Identification of differentially regulated gene targets in the Myc and Mad family proteins Nature Genetics. 23: 66-66. DOI: 10.1038/14378 |
0.636 |
|
| 1998 |
Sharma V, Grubmeyer C, Sacchettini JC. Crystal structure of quinolinic acid phosphoribosyltransferase from Mycobacterium tuberculosis: A potential TB drug target Structure. 6: 1587-1599. PMID 9862811 DOI: 10.1016/S0969-2126(98)00156-7 |
0.463 |
|
| 1998 |
Klabunde T, Eicken C, Sacchettini JC, Krebs B. Crystal structure of a plant catechol oxidase containing a dicopper center. Nature Structural Biology. 5: 1084-90. PMID 9846879 DOI: 10.1038/4193 |
0.324 |
|
| 1998 |
Rozwarski DA, Swami BM, Brewer CF, Sacchettini JC. Crystal structure of the lectin from Dioclea grandiflora complexed with core trimannoside of asparagine-linked carbohydrates. Journal of Biological Chemistry. 273: 32818-32825. PMID 9830028 DOI: 10.1074/Jbc.273.49.32818 |
0.365 |
|
| 1998 |
Banerjee A, Sugantino M, Sacchettini JC, Jacobs WR. The mabA gene from the inhA operon of Mycobacterium tuberculosis encodes a 3-ketoacyl reductase that fails to confer isoniazid resistance. Microbiology. 144: 2697-2704. PMID 9802011 DOI: 10.1099/00221287-144-10-2697 |
0.383 |
|
| 1998 |
Lim K, Owens SM, Arnold L, Sacchettini JC, Linthicum DS. Crystal structure of monoclonal 6B5 fab complexed with phencyclidine Journal of Biological Chemistry. 273: 28576-28582. PMID 9786848 DOI: 10.1074/Jbc.273.44.28576 |
0.355 |
|
| 1998 |
Degano M, Almo SC, Sacchettini JC, Schramm VL. Trypanosomal nucleoside hydrolase. A novel mechanism from the structure with a transition-state inhibitor Biochemistry. 37: 6277-6285. PMID 9572842 DOI: 10.1021/Bi973012E |
0.351 |
|
| 1998 |
Klabunde T, Sharma S, Telenti A, Jacobs WR, Sacchettini JC. Crystal structure of GyrA intein from Mycobacterium xenopi reveals structural basis of protein splicing. Nature Structural & Molecular Biology. 5: 31-36. PMID 9437427 DOI: 10.1038/Nsb0198-31 |
0.4 |
|
| 1998 |
Wang J, Lim K, Smolyar A, Teng M, Liu J, Tse AG, Liu J, Hussey RE, Chishti Y, Thomson CT, Sweet RM, Nathenson SG, Chang HC, Sacchettini JC, Reinherz EL. Atomic structure of an alphabeta T cell receptor (TCR) heterodimer in complex with an anti-TCR fab fragment derived from a mitogenic antibody. The Embo Journal. 17: 10-26. PMID 9427737 DOI: 10.1093/Emboj/17.1.10 |
0.311 |
|
| 1998 |
Rozwarski DA, Grant GA, Barton DH, Jacobs WR, Sacchettini JC. Modification of the NADH of the isoniazid target (InhA) from Mycobacterium tuberculosis. Science (New York, N.Y.). 279: 98-102. PMID 9417034 DOI: 10.1126/Science.279.5347.98 |
0.424 |
|
| 1997 |
Olsen LR, Dessen A, Gupta D, Sabesan S, Sacchettini JC, Brewer CF. X-ray crystallographic studies of unique cross-linked lattices between four isomeric biantennary oligosaccharides and soybean agglutinin. Biochemistry. 36: 15073-15080. PMID 9398234 DOI: 10.1021/BI971828+ |
0.312 |
|
| 1997 |
Sacchettini JC, Poulter CD. Creating isoprenoid diversity. Science (New York, N.Y.). 277: 1788-9. PMID 9324768 DOI: 10.1126/Science.277.5333.1788 |
0.319 |
|
| 1997 |
Zhang F, Lücke C, Baier LJ, Sacchettini JC, Hamilton JA. Solution structure of human intestinal fatty acid binding protein: implications for ligand entry and exit. Journal of Biomolecular Nmr. 9: 213-28. PMID 9204553 DOI: 10.1023/A:1018666522787 |
0.369 |
|
| 1997 |
Xu Y, Eads J, Sacchettini JC, Grubmeyer C. Kinetic mechanism of human hypoxanthine-guanine phosphoribosyltransferase: Rapid phosphoribosyl transfer chemistry Biochemistry. 36: 3700-3712. PMID 9132023 DOI: 10.1021/Bi9616007 |
0.345 |
|
| 1997 |
Eads JC, Ozturk D, Wexler TB, Grubmeyer C, Sacchettini JC. A new function for a common fold: The crystal structure of quinolinic acid phosphoribosyltransferase Structure. 5: 47-58. PMID 9016724 DOI: 10.1016/S0969-2126(97)00165-2 |
0.361 |
|
| 1997 |
Lücke C, Zhang F, Rüterjans H, Hamilton JA, Sacchettini JC. Flexibility is a likely determinant of binding specificity in the case of ileal lipid binding protein. Structure (London, England : 1993). 4: 785-800. PMID 8805562 DOI: 10.1016/S0969-2126(96)00086-X |
0.348 |
|
| 1996 |
Irigoyen M, Kowal C, Young AC, Sacchettini JC, Diamond B. Molecular mapping of the 8.12 SLE-associated idiotype specificity at the single amino acid level. Molecular Immunology. 33: 1255-65. PMID 9129162 DOI: 10.1016/S0161-5890(96)00093-4 |
0.304 |
|
| 1996 |
Tarshis LC, Proteau PJ, Kellogg BA, Sacchettini JC, Poulter CD. Regulation of product chain length by isoprenyl diphosphate synthases Proceedings of the National Academy of Sciences of the United States of America. 93: 15018-15023. PMID 8986756 DOI: 10.1073/Pnas.93.26.15018 |
0.369 |
|
| 1996 |
Sacchettini JC, Blanchard JS. The structure and function of the isoniazid target in M. tuberculosis Research in Microbiology. 147: 36-43. PMID 8761720 DOI: 10.1016/0923-2508(96)80201-4 |
0.357 |
|
| 1996 |
Degano M, Gopaul DN, Scapin G, Schramm VL, Sacchettini JC. Three-dimensional structure of the inosine-uridine nucleoside N-ribohydrolase from Crithidia fasciculata. Biochemistry. 35: 5971-81. PMID 8634238 DOI: 10.1021/Bi952999M |
0.357 |
|
| 1996 |
Gopaul DN, Meyer SL, Degano M, Sacchettini JC, Schramm VL. Inosine-uridine nucleoside hydrolase from Crithidia fasciculata. Genetic characterization, crystallization, and identification of histidine 241 as a catalytic site residue. Biochemistry. 35: 5963-70. PMID 8634237 DOI: 10.1021/Bi952998U |
0.383 |
|
| 1996 |
Baier LJ, Bogardus C, Sacchettini JC. A Polymorphism in the Human Intestinal Fatty Acid Binding Protein Alters Fatty Acid Transport across Caco-2 Cells Journal of Biological Chemistry. 271: 10892-10896. PMID 8631905 DOI: 10.1074/Jbc.271.18.10892 |
0.311 |
|
| 1995 |
Scapin G, Blanchard JS, Sacchettini JC. Three-dimensional structure of Escherichia coli dihydrodipicolinate reductase. Biochemistry. 34: 3502-12. PMID 7893645 DOI: 10.1021/Bi00011A003 |
0.417 |
|
| 1995 |
Dessen A, Quémard A, Blanchard JS, Jacobs WR, Sacchettini JC. Crystal structure and function of the isoniazid target of Mycobacterium tuberculosis Science. 267: 1638-1641. PMID 7886450 DOI: 10.1126/Science.7886450 |
0.448 |
|
| 1995 |
Dessen A, Gupta D, Sabesan S, Brewer CF, Sacchettini JC. X-ray Crystal Structure of the Soybean Agglutinin Cross-Linked with a Biantennary Analog of the Blood Group I Carbohydrate Antigen Biochemistry. 34: 4933-4942. PMID 7711015 DOI: 10.1021/Bi00015A004 |
0.378 |
|
| 1995 |
Ozturk DH, Dorfman RH, Scapin G, Sacchettini JC, Grubmeyer C. Structure and function of Salmonella typhimurium orotate phosphoribosyltransferase: Protein complementation reveals shared active sites Biochemistry. 34: 10764-10770. PMID 7545006 DOI: 10.1021/Bi00034A008 |
0.351 |
|
| 1995 |
Ozturk DH, Dorfman RH, Scapin G, Sacchettini JC, Grubmeyer C. Locations and functional roles of conserved lysine residues in Salmonella typhimurium orotate phosphoribosyltransferase Biochemistry. 34: 10755-10763. PMID 7545005 DOI: 10.1021/Bi00034A007 |
0.334 |
|
| 1995 |
Scapin G, Ozturk DH, Grubmeyer C, Sacchettini JC. The crystal structure of the orotate phosphoribosyltransferase complexed with orotate and α-D-5-phosphoribosyl-1-pyrophosphate Biochemistry. 34: 10744-10754. PMID 7545004 DOI: 10.1021/Bi00034A006 |
0.393 |
|
| 1994 |
Scapin G, Grubmeyer C, Sacchettini JC. Crystal structure of orotate phosphoribosyltransferase Biochemistry. 33: 1287-1294. PMID 8312245 DOI: 10.1021/Bi00172A001 |
0.391 |
|
| 1994 |
Maatman RG, Degano M, Van Moerkerk HT, Van Marrewijk WJ, Van der Horst DJ, Sacchettini JC, Veerkamp JH. Primary structure and binding characteristics of locust and human muscle fatty-acid-binding proteins. European Journal of Biochemistry / Febs. 221: 801-10. PMID 8174560 DOI: 10.1111/J.1432-1033.1994.Tb18794.X |
0.344 |
|
| 1994 |
Tarshis LC, Yan M, Poulter CD, Sacchettini JC. Crystal structure of recombinant farnesyl diphosphate synthase at 2.6-Å resolution Biochemistry. 33: 10871-10877. PMID 8086404 DOI: 10.1021/Bi00202A004 |
0.427 |
|
| 1994 |
Eads JC, Scapin G, Xu Y, Grubmeyer C, Sacchettini JC. The crystal structure of human hypoxanthine-guanine phosphoribosyltransferase with bound GMP Cell. 78: 325-334. PMID 8044844 DOI: 10.1016/0092-8674(94)90301-8 |
0.413 |
|
| 1994 |
Dewan JC, Grant GA, Sacchettini JC. Crystal structure of kappa-bungarotoxin at 2.3-A resolution. Biochemistry. 33: 13147-13154. PMID 7947721 DOI: 10.1021/Bi00248A026 |
0.371 |
|
| 1994 |
Young AC, Scapin G, Kromminga A, Patel SB, Veerkamp JH, Sacchettini JC. Structural studies on human muscle fatty acid binding protein at 1.4 A resolution: binding interactions with three C18 fatty acids. Structure (London, England : 1993). 2: 523-34. PMID 7922029 DOI: 10.1016/S0969-2126(00)00052-6 |
0.357 |
|
| 1994 |
Zanotti G, Scapin G, Spadon P, Veerkamp JH, Sacchettini JC. Three-dimensional structure of recombinant human muscle fatty acid-binding protein. Journal of Biological Chemistry. 267: 18541-18550. PMID 1526991 DOI: 10.2210/Pdb2Hmb/Pdb |
0.352 |
|
| 1994 |
Eads JC, Sacchettini JC, Kromminga A, Gordon JI. Escherichia coli-derived rat intestinal fatty acid binding protein with bound myristate at 1.5 A resolution and I-FABPArg106-->Gln with bound oleate at 1.74 A resolution. Journal of Biological Chemistry. 268: 26375-26385. DOI: 10.2210/Pdb1Icm/Pdb |
0.334 |
|
| 1994 |
Mikami B, Degano M, Hehre EJ, Sacchettini JC. Crystal structures of soybean beta-amylase reacted with beta-maltose and maltal: active site components and their apparent roles in catalysis. Biochemistry. 33: 7779-7787. DOI: 10.2210/Pdb1Bya/Pdb |
0.365 |
|
| 1993 |
Scapin G, Sacchettini JC, Dessen A, Bhatia M, Grubmeyer C. Primary structure and crystallization of orotate phosphoribosyltransferase from Salmonella typhimurium Journal of Molecular Biology. 230: 1304-1308. PMID 8487307 DOI: 10.1006/Jmbi.1993.1244 |
0.354 |
|
| 1993 |
Scapin G, Young AC, Kromminga A, Veerkamp JH, Gordon JI, Sacchettini JC. High resolution X-ray studies of mammalian intestinal and muscle fatty acid-binding proteins provide an opportunity for defining the chemical nature of fatty acid: protein interactions. Molecular and Cellular Biochemistry. 123: 3-13. PMID 8232266 DOI: 10.1007/Bf01076469 |
0.35 |
|
| 1993 |
Dewan JC, Mikami B, Hirose M, Sacchettini JC. Structural evidence for a pH-sensitive dilysine trigger in the hen ovotransferrin N-lobe: implications for transferrin iron release. Biochemistry. 32: 11963-11968. PMID 8218271 DOI: 10.1021/Bi00096A004 |
0.315 |
|
| 1992 |
Scapin G, Gordon JI, Sacchettini JC. Refinement of the structure of recombinant rat intestinal fatty acid-binding apoprotein at 1.2-A resolution. The Journal of Biological Chemistry. 267: 4253-69. PMID 1740465 DOI: 10.2210/Pdb1Ifc/Pdb |
0.382 |
|
| 1992 |
Green RP, Cohn SM, Sacchettini JC, Jackson KE, Gordon JI. The mouse intestinal fatty acid binding protein gene: nucleotide sequence, pattern of developmental and regional expression, and proposed structure of its protein product. Dna and Cell Biology. 11: 31-41. PMID 1739433 DOI: 10.1089/Dna.1992.11.31 |
0.319 |
|
| 1991 |
Gordon JI, Sacchettini JC, Ropson IJ, Frieden C, Li E, Rubin DC, Roth KA, Cistola DP. Intracellular fatty-acid-binding proteins and their genes: Useful models for diverse biological questions Current Opinion in Lipidology. 2: 125-137. DOI: 10.1097/00041433-199104000-00011 |
0.317 |
|
| 1990 |
Sacchettini JC, Banaszak LJ, Gordon JI. Expression of rat intestinal fatty acid binding protein in E. coli and its subsequent structural analysis: a model system for studying the molecular details of fatty acid-protein interaction. Molecular and Cellular Biochemistry. 98: 81-93. PMID 2266973 DOI: 10.1007/Bf00231371 |
0.382 |
|
| 1990 |
Cistola DP, Sacchettini JC, Gordon JI. 13C NMR studies of fatty acid-protein interactions: comparison of homologous fatty acid-binding proteins produced in the intestinal epithelium Molecular and Cellular Biochemistry. 98: 101-110. PMID 2266951 DOI: 10.1007/Bf00231373 |
0.378 |
|
| 1989 |
Sacchettini JC, Gordon JI, Banaszak LJ. Refined apoprotein structure of rat intestinal fatty acid binding protein produced in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 86: 7736-40. PMID 2682622 DOI: 10.1073/Pnas.86.20.7736 |
0.365 |
|
| 1989 |
Sacchettini JC, Gordon JI, Banaszak LJ. Crystal structure of rat intestinal fatty-acid-binding protein. Refinement and analysis of the Escherichia coli-derived protein with bound palmitate. Journal of Molecular Biology. 208: 327-39. PMID 2671390 DOI: 10.1016/0022-2836(89)90392-6 |
0.378 |
|
| 1988 |
Sacchettini JC, Frazier MW, Chiara DC, Banaszak LJ, Grant GA. Amino acid sequence of porcine heart fumarase. Biochemical and Biophysical Research Communications. 153: 435-40. PMID 3377794 DOI: 10.1016/S0006-291X(88)81243-9 |
0.321 |
|
| 1983 |
Grant GA, Sacchettini JC, Welgus HG. A collagenolytic serine protease with trypsin-like specificity from the fiddler crab Uca pugilator Biochemistry. 22: 354-358. PMID 6337626 DOI: 10.1021/Bi00271A019 |
0.356 |
|
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