| Year |
Citation |
Score |
| 2023 |
Schou M, Amini N, Takano A, Arakawa R, Dahl K, Toth M, Svedberg M, Varrone A, Halldin C. Microsome Mediated in Vitro Metabolism: A Convenient Method for the Preparation of the PET Radioligand Metabolite [F]FE-PE2I-OH for Translational Dopamine Transporter Imaging. Acs Chemical Neuroscience. 14: 3732-3736. PMID 37753876 DOI: 10.1021/acschemneuro.3c00458 |
0.329 |
|
| 2022 |
Wakabayashi Y, Strenkona P, Arakawa R, Yan X, Van Buskirk MG, Jenkins MD, Montero Santamaria JA, Maresca KP, Takano A, Liow JS, Chappie TA, Varrone A, Nag S, Zhang L, Hughes ZA, et al. First-in-human evaluation of F-PF-06445974, a PET radioligand that preferentially labels phosphodiesterase-4B. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 35772961 DOI: 10.2967/jnumed.122.263838 |
0.352 |
|
| 2022 |
Arakawa R, Takano A, Nag S, Jia Z, Amini N, Maresca KP, Zhang L, Keliher EJ, Butler CR, Piro JR, Samad TA, Smith D, Nason D, O'Neil S, Trapa P, et al. Target occupancy study and whole-body dosimetry with a MAGL PET ligand [C]PF-06809247 in non-human primates. Ejnmmi Research. 12: 13. PMID 35244788 DOI: 10.1186/s13550-022-00882-2 |
0.343 |
|
| 2020 |
Liu L, Prime ME, Lee MR, Khetarpal V, Brown CJ, Johnson PD, Azpiazu P, Chen A, Clark-Frew D, Coe S, Davis R, Dickie A, Ebneth A, Esposito S, Gadouleau E, ... ... Takano A, et al. Imaging Mutant Huntingtin Aggregates: Development of a Potential PET ligand. Journal of Medicinal Chemistry. PMID 32662649 DOI: 10.1021/Acs.Jmedchem.0C00955 |
0.429 |
|
| 2020 |
Revunov E, Johnström P, Arakawa R, Malmquist J, Jucaite A, Defay T, Takano A, Schou M. First Radiolabeling of a Ganglioside with a Positron Emitting Radionuclide: PET Demonstrates Low Exposure of Radiofluorinated GM1 in Non-human Primate Brain. Acs Chemical Neuroscience. PMID 32324990 DOI: 10.1021/Acschemneuro.0C00161 |
0.451 |
|
| 2020 |
Arakawa R, Takano A, Stenkrona P, Stepanov V, Nag S, Jahan M, Grybäck P, Bolin M, Chen L, Zhang L, He P, Villalobos A, McCarthy TJ, Halldin C, Varrone A. PET imaging of beta-secretase 1 in the human brain: radiation dosimetry, quantification, and test-retest examination of [F]PF-06684511. European Journal of Nuclear Medicine and Molecular Imaging. PMID 32140803 DOI: 10.1007/S00259-020-04739-5 |
0.455 |
|
| 2019 |
Zhang L, Butler CR, Maresca KP, Takano A, Nag S, Jia Z, Arakawa R, Piro J, Samad T, Smith DL, Nason DM, O'Neil SV, McAllister LA, Schildknegt K, Trapa P, et al. Identification and development of an irreversible monoacylglycerol lipase (MAGL) positron emission tomography (PET) radioligand with high specificity. Journal of Medicinal Chemistry. PMID 31483137 DOI: 10.1021/Acs.Jmedchem.9B00847 |
0.455 |
|
| 2019 |
Sarnyai Z, Nagy K, Patay G, Molnár M, Rosenqvist G, Tóth M, Takano A, Gulyás B, Major P, Halldin C, Varrone A. Performance Evaluation of a High Resolution Non-Human Primate PET/CT System. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 31302634 DOI: 10.2967/Jnumed.117.206243 |
0.587 |
|
| 2019 |
Yang KC, Stepanov V, Amini N, Martinsson S, Takano A, Bundgaard C, Bang-Andersen B, Sanchez C, Halldin C, Farde L, Finnema SJ. Effect of clinically relevant doses of vortioxetine and citalopram on serotonergic PET markers in the nonhuman primate brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31216565 DOI: 10.1038/S41386-019-0442-4 |
0.369 |
|
| 2019 |
Lindberg A, Lu S, Nag S, Schou M, Liow JS, Zoghbi SS, Frankland MP, Gladding RL, Morse CL, Takano A, Amini N, Elmore CS, Lee YS, Innis RB, Halldin C, et al. Synthesis and evaluation of two new candidate high-affinity full agonist PET radioligands for imaging 5-HT receptors. Nuclear Medicine and Biology. 70: 1-13. PMID 30811975 DOI: 10.1016/J.Nucmedbio.2019.01.005 |
0.386 |
|
| 2019 |
Schou M, Ewing P, Cselenyi Z, Fridén M, Takano A, Halldin C, Farde L. Pulmonary PET imaging confirms preferential lung target occupancy of an inhaled bronchodilator. Ejnmmi Research. 9: 9. PMID 30694407 DOI: 10.1186/S13550-019-0479-8 |
0.393 |
|
| 2019 |
Arakawa R, Stenkrona P, Takano A, Svensson J, Andersson M, Nag S, Asami Y, Hirano Y, Halldin C, Lundberg J. Venlafaxine ER blocks the norepinephrine transporter in the brain of patients with major depressive disorder: a PET study using [18F]FMeNER-D2. The International Journal of Neuropsychopharmacology. PMID 30649319 DOI: 10.1093/Ijnp/Pyz003 |
0.416 |
|
| 2019 |
Arakawa R, Stenkrona P, Takano A, Svensson J, Andersson M, Nag S, Asami Y, Halldin C, Lundberg J. Norepinephrine transporter occupancy of venlafaxine in patients with major depressive disorder using positron emission tomography and [18F]FMeNER-D2 European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2018.11.497 |
0.366 |
|
| 2018 |
Takano A, Chen L, Nag S, Brodney MA, Arakawa R, Chang C, Amini N, Doran SD, Dutra JK, McCarthy TJ, Nolan CE, O'Neill BT, Villalobos A, Zhang L, Halldin C. Quantitative Analysis of F-PF-06684511, a Novel PET Radioligand for Selective β-secretase 1 Imaging, in Non-human Primate Brain. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 30530832 DOI: 10.2967/Jnumed.118.217372 |
0.492 |
|
| 2018 |
Arakawa R, Takano A, Halldin C. Serotonin and norepinephrine transporter occupancy of tramadol in non-human primate using positron emission tomography. The International Journal of Neuropsychopharmacology. PMID 30346535 DOI: 10.1093/Ijnp/Pyy089 |
0.338 |
|
| 2018 |
Takano A, Nag S, Jia Z, Jahan M, Forsberg A, Arakawa R, Grybäck P, Duvey G, Halldin C, Charvin D. Characterization of [C]PXT012253 as a PET Radioligand for mGlu Allosteric Modulators in Nonhuman Primates. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. PMID 30066121 DOI: 10.1007/S11307-018-1257-0 |
0.415 |
|
| 2018 |
Yang KC, Takano A, Halldin C, Farde L, Finnema SJ. Serotonin concentration enhancers at clinically relevant doses reduce [C]AZ10419369 binding to the 5-HT receptors in the nonhuman primate brain. Translational Psychiatry. 8: 132. PMID 30013068 DOI: 10.1038/S41398-018-0178-7 |
0.392 |
|
| 2018 |
Durant ST, Zheng L, Wang Y, Chen K, Zhang L, Zhang T, Yang Z, Riches L, Trinidad AG, Fok JHL, Hunt T, Pike KG, Wilson J, Smith A, Colclough N, ... ... Takano A, et al. The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models. Science Advances. 4: eaat1719. PMID 29938225 DOI: 10.1126/Sciadv.Aat1719 |
0.327 |
|
| 2018 |
Cairns AG, Vazquez-Romero A, Mahdi-Moein M, Åden J, Elmore CS, Takano A, Arakawa R, Varrone A, Almqvist F, Schou M. Increased brain exposure of an alpha-synuclein fibrillization modulator by utilization of an activated ester pro-drug strategy. Acs Chemical Neuroscience. PMID 29901990 DOI: 10.1021/Acschemneuro.8B00236 |
0.385 |
|
| 2018 |
Chiotis K, Stenkrona P, Almkvist O, Stepanov V, Ferreira D, Arakawa R, Takano A, Westman E, Varrone A, Okamura N, Shimada H, Higuchi M, Halldin C, Nordberg A. Dual tracer tau PET imaging reveals different molecular targets for C-THK5351 and C-PBB3 in the Alzheimer brain. European Journal of Nuclear Medicine and Molecular Imaging. PMID 29752516 DOI: 10.1007/S00259-018-4012-5 |
0.429 |
|
| 2018 |
Varnäs K, Juréus A, Finnema SJ, Johnström P, Raboisson P, Amini N, Takano A, Stepanov V, Halldin C, Farde L. The metabotropic glutamate receptor 5 radioligand [C]AZD9272 identifies unique binding sites in primate brain. Neuropharmacology. PMID 29608920 DOI: 10.1016/J.Neuropharm.2018.03.039 |
0.398 |
|
| 2018 |
Takano A, Uz T, Garcia-Segovia J, Tsai M, Lahu G, Amini N, Nakao R, Jia Z, Halldin C. A Nonhuman Primate PET Study: Measurement of Brain PDE4 Occupancy by Roflumilast Using (R)-[C]Rolipram. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. PMID 29441434 DOI: 10.1007/S11307-018-1168-0 |
0.357 |
|
| 2018 |
Zhang L, Chen L, Dutra JK, Beck EM, Nag S, Takano A, Amini N, Arakawa R, Brodney MA, Buzon LM, Doran SD, Lanyon LF, McCarthy TJ, Bales KR, Nolan CE, et al. Identification of a novel positron emission tomography (PET) ligand for imaging β-site amyloid precursor protein cleaving enzyme 1 (BACE-1) in brain. Journal of Medicinal Chemistry. PMID 29356535 DOI: 10.1021/Acs.Jmedchem.7B01769 |
0.402 |
|
| 2017 |
Stepanov V, Takano A, Nakao R, Amini N, Miura S, Hasui T, Kimura H, Taniguchi T, Halldin C. Development of two fluorine-18 labeled PET radioligands targeting PDE10A and in vivo PET evaluation in nonhuman primates. Nuclear Medicine and Biology. 57: 12-19. PMID 29223715 DOI: 10.1016/J.Nucmedbio.2017.10.004 |
0.421 |
|
| 2017 |
Eriksson O, Johnström P, Cselenyi Z, Jahan M, Selvaraju RK, Jensen-Waern M, Takano A, Winzell MS, Halldin C, Skrtic S, Korsgren O. In Vivo Visualization of Beta Cells by Targeting of GPR44. Diabetes. PMID 29208633 DOI: 10.2337/Db17-0764 |
0.307 |
|
| 2017 |
McClure KF, Piotrowski DW, Petersen D, Wei L, Xiao J, Londregan AT, Kamlet A, Dechert-Schmitt AM, Raymer B, Ruggeri RB, Canterbury D, Limberakis C, Liras S, DaSilva-Jardine P, Dullea RG, ... ... Takano A, et al. Liver-Targeted Small Molecule Inhibitors of Proprotein Convertase Subtilisin/Kexin Type 9 Synthesis. Angewandte Chemie (International Ed. in English). PMID 29073340 DOI: 10.1002/Anie.201708744 |
0.306 |
|
| 2017 |
Lindberg A, Nag S, Schou M, Takano A, Matsumoto J, Amini N, Elmore CS, Farde L, Pike VW, Halldin C. [(11)C]AZ10419096 - a full antagonist PET radioligand for imaging brain 5-HT1B receptors. Nuclear Medicine and Biology. 54: 34-40. PMID 28950161 DOI: 10.1016/J.Nucmedbio.2017.07.007 |
0.44 |
|
| 2017 |
Arakawa R, Farde L, Matsumoto J, Kanegawa N, Yakushev I, Yang KC, Takano A. Potential Effect of Prolonged Sevoflurane Anesthesia on the Kinetics of [(11)C]Raclopride in Non-human Primates. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. PMID 28916921 DOI: 10.1007/S11307-017-1120-8 |
0.452 |
|
| 2017 |
Arakawa R, Stenkrona P, Takano A, Nag S, Maior RS, Halldin C. Test-retest reproducibility of [(11)C]-L-deprenyl-D2 binding to MAO-B in the human brain. Ejnmmi Research. 7: 54. PMID 28634836 DOI: 10.1186/S13550-017-0301-4 |
0.422 |
|
| 2017 |
Johnström P, Gutierrez PM, Varnäs K, Schou M, Takano A, Jones L, Mugundu G, McCoon P, Lyne P, Infante J, Falchook G, Patel M, Karlix J, Merchant M, Clarke J, et al. Abstract 2641: AZD4635 A2Areceptor occupancy in cynomolgus monkey using PET and its application to an oncology clinical development program Cancer Research. 77: 2641-2641. DOI: 10.1158/1538-7445.Am2017-2641 |
0.402 |
|
| 2017 |
Chiotis K, Stenkrona P, Almkvist O, Arakawa R, Takano A, Stepanov V, Varrone A, Higuchi M, Halldin C, Nordberg A. [IC-P-178]: HEAD-TO-HEAD IN VIVO
COMPARISON OF TAU-SPECIFIC PET TRACERS IN ALZHEIMER's DISEASE: [11
C]THK5351 VERSUS [11
C]PBB3 PET IMAGING Alzheimer's & Dementia. 13: P133-P133. DOI: 10.1016/J.Jalz.2017.06.2553 |
0.409 |
|
| 2016 |
Igawa H, Stepanov V, Tari L, Okuda S, Yamamoto S, Kasai S, Nagisa Y, Häggkvist J, Svedberg M, Tóth M, Takano A, Halldin C. Development of a Novel Carbon-11 Labeled PET Radioligand for Melanin-Concentrating Hormone Receptor 1. Current Radiopharmaceuticals. PMID 28034352 DOI: 10.2174/1874471009666161230113630 |
0.397 |
|
| 2016 |
Yang KC, Stepanov V, Amini N, Martinsson S, Takano A, Nielsen J, Bundgaard C, Bang-Andersen B, Grimwood S, Halldin C, Farde L, Finnema SJ. Characterization of [(11)C]Lu AE92686 as a PET radioligand for phosphodiesterase 10A in the nonhuman primate brain. European Journal of Nuclear Medicine and Molecular Imaging. PMID 27817159 DOI: 10.1007/S00259-016-3544-9 |
0.445 |
|
| 2016 |
Takano A, Varrone A, Gulyás B, Salvadori P, Gee A, Windhorst A, Vercouillie J, Bormans G, Lammertsma AA, Halldin C. Guidelines to PET measurements of the target occupancy in the brain for drug development. European Journal of Nuclear Medicine and Molecular Imaging. PMID 27514528 DOI: 10.1007/S00259-016-3476-4 |
0.529 |
|
| 2016 |
Takano A, Stenkrona P, Stepanov V, Amini N, Martinsson S, Tsai M, Goldsmith P, Xie J, Wu J, Uz T, Halldin C, Macek TA. A human [(11)C]T-773 PET study of PDE10A binding after oral administration of TAK-063, a PDE10A inhibitor. Neuroimage. PMID 27423256 DOI: 10.1016/J.Neuroimage.2016.06.047 |
0.485 |
|
| 2016 |
Varnäs K, Finnema SJ, Stepanov V, Takano A, Tóth M, Svedberg M, Nielsen SM, Khanzhin NA, Juhl K, Bang-Andersen B, Halldin C, Farde L. Neurokinin-3 receptor binding in guinea pig, monkey and human brain: In vitro and in vivo imaging using the novel radioligand, [18F]Lu AF10628. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). PMID 26993630 DOI: 10.1093/Ijnp/Pyw023 |
0.368 |
|
| 2016 |
Takano A, Stepanov V, Nakao R, Amini N, Gulyás B, Kimura H, Halldin C. Brain PET measurement of PDE10A occupancy by TAK-063, a new PDE10A inhibitor, using [(11) C]T-773 in nonhuman primates. Synapse (New York, N.Y.). PMID 26878349 DOI: 10.1002/Syn.21896 |
0.606 |
|
| 2015 |
Schou M, Varnas K, Jureus A, Ahlgren C, Malmquist J, Häggkvist J, Tari L, Wesolowski SS, Throner SR, Brown DG, Nilsson M, Johnström P, Finnema SJ, Nakao R, Amini N, ... Takano A, et al. Discovery and preclinical validation of [11C]AZ13153556, a novel probe for the histamine type-3 receptor. Acs Chemical Neuroscience. PMID 26529287 DOI: 10.1021/Acschemneuro.5B00268 |
0.382 |
|
| 2015 |
Rahman O, Takano A, Amini N, Dahl K, Kanegawa N, Långström B, Farde L, Halldin C. Synthesis of ([(11)C]carbonyl)raclopride and a comparison with ([(11)C]methyl)raclopride in a monkey PET study. Nuclear Medicine and Biology. 42: 893-8. PMID 26272268 DOI: 10.1016/J.Nucmedbio.2015.07.003 |
0.393 |
|
| 2015 |
Takano A, Stepanov V, Gulyás B, Nakao R, Amini N, Miura S, Kimura H, Taniguchi T, Halldin C. Evaluation of a novel PDE10A PET radioligand, [(11) C]T-773, in nonhuman primates: Brain and whole body PET and brain autoradiography. Synapse (New York, N.Y.). 69: 345-55. PMID 25892433 DOI: 10.1002/Syn.21821 |
0.632 |
|
| 2015 |
Stepanov V, Miura S, Takano A, Amini N, Nakao R, Hasui T, Nakashima K, Taniguchi T, Kimura H, Kuroita T, Halldin C. Development of a series of novel carbon-11 labeled PDE10A inhibitors. Journal of Labelled Compounds & Radiopharmaceuticals. 58: 202-8. PMID 25891816 DOI: 10.1002/Jlcr.3284 |
0.411 |
|
| 2015 |
Schou M, Varnäs K, Lundquist S, Nakao R, Amini N, Takano A, Finnema SJ, Halldin C, Farde L. Large Variation in Brain Exposure of Reference CNS Drugs: a PET Study in Nonhuman Primates. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). PMID 25813017 DOI: 10.1093/Ijnp/Pyv036 |
0.338 |
|
| 2015 |
Tóth M, Häggkvist J, Stepanov V, Takano A, Nakao R, Amini N, Miura S, Kimura H, Taniguchi T, Gulyás B, Halldin C. Molecular Imaging of PDE10A Knockout Mice with a Novel PET Radiotracer: [(11)C]T-773. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 17: 445-9. PMID 25622810 DOI: 10.1007/S11307-015-0822-Z |
0.567 |
|
| 2015 |
Harada A, Suzuki K, Miura S, Hasui T, Kamiguchi N, Ishii T, Taniguchi T, Kuroita T, Takano A, Stepanov V, Halldin C, Kimura H. Characterization of the binding properties of T-773 as a PET radioligand for phosphodiesterase 10A. Nuclear Medicine and Biology. 42: 146-54. PMID 25451212 DOI: 10.1016/J.Nucmedbio.2014.09.005 |
0.413 |
|
| 2015 |
Takano A, Stenkrona P, Stepanov V, Amini N, Martinsson S, Tsai M, Goldsmith P, Wu J, Xie J, Uz T, Macek T, Halldin C. P.1.i.028 Brain phosphodiesterase 10A occupancy measured by PET after oral administration of TAK-063, a newly developed phosphodiesterase 10A inhibitor, in human volunteers European Neuropsychopharmacology. 25: S316. DOI: 10.1016/S0924-977X(15)30387-4 |
0.339 |
|
| 2015 |
Takano A, Stepanov V, Stenkrona P, Amini N, Martinsson S, Tsai M, Goldsmith P, Wu J, Xie J, Uz T, Macek T, Halldin C. P.1.i.027 Quantitative analysis and test-retest reproducibility of a new phosphodiesterase 10A PET radioligand [11C]T-773 in human brain European Neuropsychopharmacology. 25: S315. DOI: 10.1016/S0924-977X(15)30386-2 |
0.394 |
|
| 2015 |
Takano A, Stepanov V, Nakao R, Amini N, Kimura H, Halldin C. P.1.i.025 Brain PET measurement of phosphodiesterase 10A occupancy by TAK-063, a new phosphodiesterase 10A inhibitor, using [11C]T-773 in nonhuman primates European Neuropsychopharmacology. 25: S313-S314. DOI: 10.1016/S0924-977X(15)30384-9 |
0.348 |
|
| 2014 |
Gourand F, Emond P, Bergström JP, Takano A, Gulyás B, Guilloteau D, Barré L, Halldin C. A radiometabolite study of the serotonin transporter PET radioligand [(11)C]MADAM. Nuclear Medicine and Biology. 41: 501-6. PMID 24857865 DOI: 10.1016/J.Nucmedbio.2014.03.022 |
0.583 |
|
| 2014 |
Takano A, Gulyás B, Varnäs K, Little PB, Noerregaard PK, Jensen NO, Elling CE, Halldin C. Low brain CB1 receptor occupancy by a second generation CB1 receptor antagonist TM38837 in comparison with rimonabant in nonhuman primates: a PET study. Synapse (New York, N.Y.). 68: 89-97. PMID 24293119 DOI: 10.1002/Syn.21721 |
0.586 |
|
| 2013 |
Nyberg S, Jucaite A, Takano A, Kågedal M, Cselényi Z, Halldin C, Farde L. Norepinephrine transporter occupancy in the human brain after oral administration of quetiapine XR. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 2235-44. PMID 23809226 DOI: 10.1017/S1461145713000680 |
0.444 |
|
| 2013 |
Takano A, Piehl F, Hillert J, Varrone A, Nag S, Gulyás B, Stenkrona P, Villemagne VL, Rowe CC, Macdonell R, Tawil NA, Kucinski T, Zimmermann T, Schultze-Mosgau M, Thiele A, et al. In vivo TSPO imaging in patients with multiple sclerosis: a brain PET study with [18F]FEDAA1106. Ejnmmi Research. 3: 30. PMID 23618062 DOI: 10.1186/2191-219X-3-30 |
0.567 |
|
| 2013 |
Varrone A, Mattsson P, Forsberg A, Takano A, Nag S, Gulyás B, Borg J, Boellaard R, Al-Tawil N, Eriksdotter M, Zimmermann T, Schultze-Mosgau M, Thiele A, Hoffmann A, Lammertsma AA, et al. In vivo imaging of the 18-kDa translocator protein (TSPO) with [18F]FEDAA1106 and PET does not show increased binding in Alzheimer's disease patients. European Journal of Nuclear Medicine and Molecular Imaging. 40: 921-31. PMID 23436070 DOI: 10.1007/S00259-013-2359-1 |
0.534 |
|
| 2013 |
Ikoma Y, Takano A, Varrone A, Halldin C. Graphic plot analysis for estimating binding potential of translocator protein (TSPO) in positron emission tomography studies with [¹â¸F]FEDAA1106. Neuroimage. 69: 78-86. PMID 23247191 DOI: 10.1016/J.Neuroimage.2012.12.009 |
0.334 |
|
| 2013 |
Jucaite A, Takano A, Boström E, Jostell KG, Stenkrona P, Halldin C, Segerdahl M, Nyberg S. AZD5213: a novel histamine H3 receptor antagonist permitting high daytime and low nocturnal H3 receptor occupancy, a PET study in human subjects. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 1231-9. PMID 23217964 DOI: 10.1017/S1461145712001411 |
0.333 |
|
| 2012 |
Fuchigami T, Takano A, Gulyás B, Jia Z, Finnema SJ, Andersson JD, Nakao R, Magata Y, Haratake M, Nakayama M, Halldin C. Synthesis and evaluation of 2-chloro N-[(S)-{(S)-1-[11 C]methylpiperidin-2-yl} (phenyl)methyl]3-trifluoromethyl-benzamide ([11 C]N-methyl-SSR504734) as a PET radioligand for glycine transporter 1. Ejnmmi Research. 2: 37. PMID 22776065 DOI: 10.1186/2191-219X-2-37 |
0.601 |
|
| 2012 |
Varrone A, Gulyás B, Takano A, Stabin MG, Jonsson C, Halldin C. Simplified quantification and whole-body distribution of [18F]FE-PE2I in nonhuman primates: prediction for human studies. Nuclear Medicine and Biology. 39: 295-303. PMID 22033024 DOI: 10.1016/J.Nucmedbio.2011.08.004 |
0.558 |
|
| 2011 |
Takano A, Gulyás B, Varrone A, Karlsson P, Sjoholm N, Larsson S, Jonsson C, Odh R, Sparks R, Al Tawil N, Hoffmann A, Zimmermann T, Thiele A, Halldin C. Biodistribution and radiation dosimetry of the 18 kDa translocator protein (TSPO) radioligand [18F]FEDAA1106: a human whole-body PET study. European Journal of Nuclear Medicine and Molecular Imaging. 38: 2058-65. PMID 21732107 DOI: 10.1007/S00259-011-1864-3 |
0.593 |
|
| 2011 |
Takano A, Nag S, Gulyás B, Halldin C, Farde L. NET occupancy by clomipramine and its active metabolite, desmethylclomipramine, in non-human primates in vivo. Psychopharmacology. 216: 279-86. PMID 21336575 DOI: 10.1007/S00213-011-2212-9 |
0.608 |
|
| 2011 |
Gulyás B, Vas A, Tóth M, Takano A, Varrone A, Cselényi Z, Schain M, Mattsson P, Halldin C. Age and disease related changes in the translocator protein (TSPO) system in the human brain: positron emission tomography measurements with [11C]vinpocetine. Neuroimage. 56: 1111-21. PMID 21320609 DOI: 10.1016/J.Neuroimage.2011.02.020 |
0.564 |
|
| 2011 |
Varrone A, Tóth M, Steiger C, Takano A, Guilloteau D, Ichise M, Gulyás B, Halldin C. Kinetic analysis and quantification of the dopamine transporter in the nonhuman primate brain with 11C-PE2I and 18F-FE-PE2I. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 52: 132-9. PMID 21189414 DOI: 10.2967/Jnumed.110.077651 |
0.512 |
|
| 2011 |
Varnäs K, Nyberg S, Halldin C, Varrone A, Takano A, Karlsson P, Andersson J, McCarthy D, Smith M, Pierson ME, Söderström J, Farde L. Quantitative analysis of [11C]AZ10419369 binding to 5-HT1B receptors in human brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 113-23. PMID 20424633 DOI: 10.1038/Jcbfm.2010.55 |
0.403 |
|
| 2010 |
Saijo T, Takano A, Suhara T, Arakawa R, Okumura M, Ichimiya T, Ito H, Okubo Y. Effect of electroconvulsive therapy on 5-HT1A receptor binding in patients with depression: a PET study with [11C]WAY 100635. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 13: 785-91. PMID 20067660 DOI: 10.1017/S1461145709991209 |
0.325 |
|
| 2010 |
Varrone A, Tóth M, Steiger C, Takano A, Guilloteau D, Ichise M, Gulyás B, Halldin C. Kinetic analysis and quantification of the dopamine transporter in the non-human primate brain with [11C]PE2I and [18F]FE-PE2I Neuroimage. 52. DOI: 10.1016/J.Neuroimage.2010.04.137 |
0.404 |
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| 2010 |
Takano A, Gulyás B, Halldin C. Clomipramine and the active metabolite, desmethylclomipramine, occupy NET in non-human primate measured by PET Neuroimage. 52: S106. DOI: 10.1016/J.Neuroimage.2010.04.085 |
0.572 |
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| 2009 |
Takano A, Gulyás B, Varrone A, Halldin C. Comparative evaluations of norepinephrine transporter radioligands with reference tissue models in rhesus monkeys: (S,S)-[18F]FMeNER-D2 and (S,S)-[11C]MeNER. European Journal of Nuclear Medicine and Molecular Imaging. 36: 1885-91. PMID 19565240 DOI: 10.1007/S00259-009-1194-X |
0.568 |
|
| 2009 |
Varrone A, Steiger C, Schou M, Takano A, Finnema SJ, Guilloteau D, Gulyás B, Halldin C. In vitro autoradiography and in vivo evaluation in cynomolgus monkey of [18F]FE-PE2I, a new dopamine transporter PET radioligand. Synapse (New York, N.Y.). 63: 871-80. PMID 19562698 DOI: 10.1002/Syn.20670 |
0.614 |
|
| 2009 |
Takano A, Gulyás B, Varrone A, Maguire RP, Halldin C. Saturated norepinephrine transporter occupancy by atomoxetine relevant to clinical doses: a rhesus monkey study with (S,S)-[(18)F]FMeNER-D (2). European Journal of Nuclear Medicine and Molecular Imaging. 36: 1308-14. PMID 19300997 DOI: 10.1007/S00259-009-1118-9 |
0.597 |
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| 2008 |
Takano A, Varrone A, Gulyás B, Karlsson P, Tauscher J, Halldin C. Mapping of the norepinephrine transporter in the human brain using PET with (S,S)-[18F]FMeNER-D2. Neuroimage. 42: 474-82. PMID 18617423 DOI: 10.1016/J.Neuroimage.2008.05.040 |
0.612 |
|
| 2008 |
Pierson ME, Andersson J, Nyberg S, McCarthy DJ, Finnema SJ, Varnäs K, Takano A, Karlsson P, Gulyás B, Medd AM, Lee CM, Powell ME, Heys JR, Potts W, Seneca N, et al. [11C]AZ10419369: a selective 5-HT1B receptor radioligand suitable for positron emission tomography (PET). Characterization in the primate brain. Neuroimage. 41: 1075-85. PMID 18434202 DOI: 10.1016/J.Neuroimage.2008.02.063 |
0.606 |
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| 2008 |
Takano A, Halldin C, Varrone A, Karlsson P, Sjöholm N, Stubbs JB, Schou M, Airaksinen AJ, Tauscher J, Gulyás B. Biodistribution and radiation dosimetry of the norepinephrine transporter radioligand (S,S)-[18F]FMeNER-D2: a human whole-body PET study. European Journal of Nuclear Medicine and Molecular Imaging. 35: 630-6. PMID 18000665 DOI: 10.1007/S00259-007-0622-Z |
0.61 |
|
| 2008 |
Takano A, Gulyás B, Varrone A, Karlsson P, Schou M, Airaksinen AJ, Vandenhende F, Tauscher J, Halldin C. Imaging the norepinephrine transporter with positron emission tomography: initial human studies with (S,S)-[18F]FMeNER-D2. European Journal of Nuclear Medicine and Molecular Imaging. 35: 153-7. PMID 17909794 DOI: 10.1007/S00259-007-0598-8 |
0.633 |
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| 2008 |
Vas A, Shchukin Y, Karrenbauer VD, Cselényi Z, Kostulas K, Hillert J, Savic I, Takano A, Halldin C, Gulyás B. Functional neuroimaging in multiple sclerosis with radiolabelled glia markers: preliminary comparative PET studies with [11C]vinpocetine and [11C]PK11195 in patients. Journal of the Neurological Sciences. 264: 9-17. PMID 17727889 DOI: 10.1016/J.Jns.2007.07.018 |
0.601 |
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| 2008 |
Nyberg S, Takano A, Jucaite A, Karlsson P, McCarthy D, Kågedal M, Eriksson H, Lee C, Halldin C, Farde L. P.1.e.019 PET-measured occupancy of the norepinephrene transporter by extended release quetiapine fumarate (quetiapine XR) in brains of healthy subjects European Neuropsychopharmacology. 18: S270. DOI: 10.1016/S0924-977X(08)70352-3 |
0.365 |
|
| 2008 |
Varrone A, Schou M, Steiger C, Takano A, Finnema S, Guilloteau D, Gulyás B, Halldin C. Autoradiography and in vivo evaluation in cynomolgus monkey of [18F]FE-PE2I, a new dopamine transporter PET radioligand Neuroimage. 41. DOI: 10.1016/J.Neuroimage.2008.04.112 |
0.401 |
|
| 2008 |
Varnäs K, Nyberg S, Halldin C, Varrone A, Takano A, Karlsson P, McCarthy D, Smith M, Pierson ME, Söderström J, Farde L. Quantitative analyses of [11C]AZ10419369 binding to 5-HT1B receptors in the human brain Neuroimage. 41. DOI: 10.1016/J.Neuroimage.2008.04.073 |
0.368 |
|
| 2008 |
Takano A, Varrone A, Gulyás B, Karlsson P, Tauscher J, Halldin C. Mapping of the norepinephrine transporter in man using PET with (S,S)-[18F]FMeNER-D2 Neuroimage. 41: T103. DOI: 10.1016/J.Neuroimage.2008.04.072 |
0.567 |
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| 2007 |
Nyberg S, Takano A, Grimm S, Gulyas B, McCarthy D, Lee C, Goldstein J, Halldin C, Farde L. P.1.c.022 PET-measured D2, 5-HT2, and norepinephrine transporter (NET) occupancy by quetiapine and N-desalkyl-quetiapine in non-human primates European Neuropsychopharmacology. 17: S254-S255. DOI: 10.1016/S0924-977X(07)70346-2 |
0.375 |
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| 2006 |
Morimoto T, Ito H, Takano A, Ikoma Y, Seki C, Okauchi T, Tanimoto K, Ando A, Shiraishi T, Yamaya T, Suhara T. Effects of image reconstruction algorithm on neurotransmission PET studies in humans: comparison between filtered backprojection and ordered subsets expectation maximization. Annals of Nuclear Medicine. 20: 237-43. PMID 16715957 |
0.326 |
|
| 2006 |
Fujimura Y, Ikoma Y, Yasuno F, Suhara T, Ota M, Matsumoto R, Nozaki S, Takano A, Kosaka J, Zhang MR, Nakao R, Suzuki K, Kato N, Ito H. Quantitative analyses of 18F-FEDAA1106 binding to peripheral benzodiazepine receptors in living human brain. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 47: 43-50. PMID 16391186 |
0.315 |
|
| 2004 |
Maeda J, Suhara T, Zhang MR, Okauchi T, Yasuno F, Ikoma Y, Inaji M, Nagai Y, Takano A, Obayashi S, Suzuki K. Novel peripheral benzodiazepine receptor ligand [11C]DAA1106 for PET: an imaging tool for glial cells in the brain. Synapse (New York, N.Y.). 52: 283-91. PMID 15103694 DOI: 10.1002/syn.20027 |
0.314 |
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