Gregory Longmore - Publications

Affiliations: 
Biology & Biomedical Sciences (Molecular Cell Biology) Washington University, Saint Louis, St. Louis, MO 
Area:
Cell Biology, Human Development

57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Schab AM, Greenwade MM, Stock E, Lomonosova E, Cho K, Grither WR, Noia H, Wilke D, Mullen MM, Hagemann AR, Hagemann IS, Thaker PH, Kuroki LM, McCourt CK, Khabele D, ... ... Longmore GD, et al. Stromal DDR2 promotes ovarian cancer metastasis through regulation of metabolism and secretion of extracellular matrix proteins. Molecular Cancer Research : McR. PMID 37527178 DOI: 10.1158/1541-7786.MCR-23-0347  0.304
2023 Hwang PY, Mathur J, Cao Y, Almeida J, Ye J, Morikis V, Cornish D, Clarke M, Stewart SA, Pathak A, Longmore GD. A Cdh3-β-catenin-laminin signaling axis in a subset of breast tumor leader cells control leader cell polarization and directional collective migration. Developmental Cell. 58: 34-50.e9. PMID 36626870 DOI: 10.1016/j.devcel.2022.12.005  0.316
2021 Bota-Rabassedas N, Banerjee P, Niu Y, Cao W, Luo J, Xi Y, Tan X, Sheng K, Ahn YH, Lee S, Parra ER, Rodriguez-Canales J, Albritton J, Weiger M, Liu X, ... ... Longmore GD, et al. Contextual cues from cancer cells govern cancer-associated fibroblast heterogeneity. Cell Reports. 35: 109009. PMID 33882319 DOI: 10.1016/j.celrep.2021.109009  0.312
2019 Longmore GD, Hwang PY, Brenot A, George SC, King AC. Randomly distributed K14+ breast tumor cells polarize to the leading edge to direct collective migration in response to chemical and mechanical environmental cues. Cancer Research. PMID 30862718 DOI: 10.1158/0008-5472.Can-18-2828  0.311
2019 Nozaki M, Yabuta N, Fukuzawa M, Mukai S, Okamoto A, Sasakura T, Fukushima K, Naito Y, Longmore GD, Nojima H. LATS1/2 kinases trigger self-renewal of cancer stem cells in aggressive oral cancer. Oncotarget. 10: 1014-1030. PMID 30800215 DOI: 10.18632/oncotarget.26583  0.304
2017 Fuh K, Gibson A, Wilke D, Ilagan M, Hagemann A, McCourt C, Thaker P, Mutch D, Powell M, Longmore G. Abstract AP18: FUNCTIONAL GENOMIC SCREEN FOR ATTACHMENT AND INVASION IN METASTATIC OVARIAN CANCER Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Ovcasymp16-Ap18  0.388
2016 Jagannathan R, Schimizzi GV, Zhang K, Loza AJ, Yabuta N, Nojima H, Longmore GD. AJUBA LIM proteins limit Hippo activity in proliferating cells by sequestering the Hippo core kinase complex in the cytosol. Molecular and Cellular Biology. PMID 27457617 DOI: 10.1128/Mcb.00136-16  0.686
2016 Schimizzi GV, Maher MT, Loza AJ, Longmore GD. Disruption of the Cdc42/Par6/aPKC or Dlg/Scrib/Lgl Polarity Complex Promotes Epithelial Proliferation via Overlapping Mechanisms. Plos One. 11: e0159881. PMID 27454609 DOI: 10.1371/Journal.Pone.0159881  0.308
2016 Ruhland MK, Loza AJ, Capietto AH, Luo X, Knolhoff BL, Flanagan KC, Belt BA, Alspach E, Leahy K, Luo J, Schaffer A, Edwards JR, Longmore G, Faccio R, DeNardo DG, et al. Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis. Nature Communications. 7: 11762. PMID 27272654 DOI: 10.1038/Ncomms11762  0.422
2015 Divine L, Grither W, Gibson A, Longmore G, Fuh K. The receptor tyrosine kinase discoidin domain receptor 2 promotes invasion via epithelial mesenchymal transition in ovarian cancer Gynecologic Oncology. 139: 189. DOI: 10.1016/J.Ygyno.2015.07.047  0.304
2014 Yashiro H, Loza AJ, Skeath JB, Longmore GD. Rho1 regulates adherens junction remodeling by promoting recycling endosome formation through activation of myosin II. Molecular Biology of the Cell. 25: 2956-69. PMID 25079692 DOI: 10.1091/Mbc.E14-04-0894  0.338
2013 Bajpai S, Feng Y, Wirtz D, Longmore GD. β-Catenin serves as a clutch between low and high intercellular E-cadherin bond strengths. Biophysical Journal. 105: 2289-300. PMID 24268141 DOI: 10.1016/J.Bpj.2013.09.044  0.304
2013 Giri A, Bajpai S, Trenton N, Jayatilaka H, Longmore GD, Wirtz D. The Arp2/3 complex mediates multigeneration dendritic protrusions for efficient 3-dimensional cancer cell migration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 4089-99. PMID 23796785 DOI: 10.1096/Fj.12-224352  0.365
2012 Kim DH, Khatau SB, Feng Y, Walcott S, Sun SX, Longmore GD, Wirtz D. Actin cap associated focal adhesions and their distinct role in cellular mechanosensing. Scientific Reports. 2: 555. PMID 22870384 DOI: 10.1038/Srep00555  0.335
2012 Lee MH, Wu PH, Staunton JR, Ros R, Longmore GD, Wirtz D. Mismatch in mechanical and adhesive properties induces pulsating cancer cell migration in epithelial monolayer. Biophysical Journal. 102: 2731-41. PMID 22735523 DOI: 10.1016/J.Bpj.2012.05.005  0.367
2012 Zhang K, Rodriguez-Aznar E, Yabuta N, Owen RJ, Mingot JM, Nojima H, Nieto MA, Longmore GD. Lats2 kinase potentiates Snail1 activity by promoting nuclear retention upon phosphorylation. The Embo Journal. 31: 29-43. PMID 21952048 DOI: 10.1038/emboj.2011.357  0.402
2011 Nola S, Daigaku R, Smolarczyk K, Carstens M, Martin-Martin B, Longmore G, Bailly M, Braga VM. Ajuba is required for Rac activation and maintenance of E-cadherin adhesion. The Journal of Cell Biology. 195: 855-71. PMID 22105346 DOI: 10.1083/Jcb.201107162  0.539
2011 Tran DD, Corsa CA, Biswas H, Aft RL, Longmore GD. Temporal and spatial cooperation of Snail1 and Twist1 during epithelial-mesenchymal transition predicts for human breast cancer recurrence. Molecular Cancer Research : McR. 9: 1644-57. PMID 22006115 DOI: 10.1158/1541-7786.MCR-11-0371  0.325
2010 Warner SJ, Longmore GD. Context-dependent compensatory proliferation in epithelial homeostasis and tumorigenesis. Cell Cycle (Georgetown, Tex.). 9: 4037-8. PMID 20935485 DOI: 10.4161/Cc.9.20.13562  0.651
2010 Fraley SI, Feng Y, Krishnamurthy R, Kim DH, Celedon A, Longmore GD, Wirtz D. A distinctive role for focal adhesion proteins in three-dimensional cell motility. Nature Cell Biology. 12: 598-604. PMID 20473295 DOI: 10.1038/Ncb2062  0.399
2010 Warner SJ, Yashiro H, Longmore GD. The Cdc42/Par6/aPKC polarity complex regulates apoptosis-induced compensatory proliferation in epithelia. Current Biology : Cb. 20: 677-86. PMID 20381350 DOI: 10.1016/J.Cub.2010.03.025  0.66
2010 Alford SK, Wang Y, Feng Y, Longmore GD, Elbert DL. Prediction of sphingosine 1-phosphate-stimulated endothelial cell migration rates using biochemical measurements. Annals of Biomedical Engineering. 38: 2775-90. PMID 20358290 DOI: 10.1007/S10439-010-0014-6  0.381
2010 Das Thakur M, Feng Y, Jagannathan R, Seppa MJ, Skeath JB, Longmore GD. Ajuba LIM proteins are negative regulators of the Hippo signaling pathway. Current Biology : Cb. 20: 657-62. PMID 20303269 DOI: 10.1016/J.Cub.2010.02.035  0.78
2010 Ngu H, Feng Y, Lu L, Oswald SJ, Longmore GD, Yin FC. Effect of focal adhesion proteins on endothelial cell adhesion, motility and orientation response to cyclic strain. Annals of Biomedical Engineering. 38: 208-22. PMID 19856213 DOI: 10.1007/S10439-009-9826-7  0.413
2009 Warner SJ, Longmore GD. Cdc42 antagonizes Rho1 activity at adherens junctions to limit epithelial cell apical tension. The Journal of Cell Biology. 187: 119-33. PMID 19805632 DOI: 10.1083/Jcb.200906047  0.704
2009 Warner SJ, Longmore GD. Distinct functions for Rho1 in maintaining adherens junctions and apical tension in remodeling epithelia. The Journal of Cell Biology. 185: 1111-25. PMID 19506041 DOI: 10.1083/Jcb.200901029  0.685
2009 Schindler EM, Hindes A, Gribben EL, Burns CJ, Yin Y, Lin MH, Owen RJ, Longmore GD, Kissling GE, Arthur JS, Efimova T. p38delta Mitogen-activated protein kinase is essential for skin tumor development in mice. Cancer Research. 69: 4648-55. PMID 19458068 DOI: 10.1158/0008-5472.CAN-08-4455  0.307
2008 Luderer HF, Bai S, Longmore GD. The LIM protein LIMD1 influences osteoblast differentiation and function. Experimental Cell Research. 314: 2884-94. PMID 18657804 DOI: 10.1016/J.Yexcr.2008.06.003  0.751
2008 Epple H, Cremasco V, Zhang K, Mao D, Longmore GD, Faccio R. Phospholipase Cgamma2 modulates integrin signaling in the osteoclast by affecting the localization and activation of Src kinase. Molecular and Cellular Biology. 28: 3610-22. PMID 18378693 DOI: 10.1128/Mcb.00259-08  0.767
2008 Langer EM, Feng Y, Zhaoyuan H, Rauscher FJ, Kroll KL, Longmore GD. Ajuba LIM proteins are snail/slug corepressors required for neural crest development in Xenopus. Developmental Cell. 14: 424-36. PMID 18331720 DOI: 10.1016/j.devcel.2008.01.005  0.324
2008 Wacker BK, Alford SK, Scott EA, Das Thakur M, Longmore GD, Elbert DL. Endothelial cell migration on RGD-peptide-containing PEG hydrogels in the presence of sphingosine 1-phosphate. Biophysical Journal. 94: 273-85. PMID 17827231 DOI: 10.1529/Biophysj.107.109074  0.743
2007 Feng Y, Zhao H, Luderer HF, Epple H, Faccio R, Ross FP, Teitelbaum SL, Longmore GD. The LIM protein, Limd1, regulates AP-1 activation through an interaction with Traf6 to influence osteoclast development. The Journal of Biological Chemistry. 282: 39-48. PMID 17092936 DOI: 10.1074/Jbc.M607399200  0.719
2005 Kisseleva M, Feng Y, Ward M, Song C, Anderson RA, Longmore GD. The LIM protein Ajuba regulates phosphatidylinositol 4,5-bisphosphate levels in migrating cells through an interaction with and activation of PIPKI alpha. Molecular and Cellular Biology. 25: 3956-66. PMID 15870270 DOI: 10.1128/MCB.25.10.3956-3966.2005  0.377
2005 Pratt SJ, Epple H, Ward M, Feng Y, Braga VM, Longmore GD. The LIM protein Ajuba influences p130Cas localization and Rac1 activity during cell migration. The Journal of Cell Biology. 168: 813-24. PMID 15728191 DOI: 10.1083/Jcb.200406083  0.775
2004 Hadland BK, Huppert SS, Kanungo J, Xue Y, Jiang R, Gridley T, Conlon RA, Cheng AM, Kopan R, Longmore GD. A requirement for Notch1 distinguishes 2 phases of definitive hematopoiesis during development. Blood. 104: 3097-105. PMID 15251982 DOI: 10.1182/Blood-2004-03-1224  0.322
2004 Young AP, Longmore GD. Differential regulation of apoptotic genes by Rb in human versus mouse cells. Oncogene. 23: 2587-99. PMID 15048095 DOI: 10.1038/Sj.Onc.1207330  0.624
2004 Young AP, Longmore GD. Differences in stability of repressor complexes at promoters underlie distinct roles for Rb family members. Oncogene. 23: 814-23. PMID 14737116 DOI: 10.1038/Sj.Onc.1207187  0.587
2004 Young AP, Longmore GD. Ras protects Rb family null fibroblasts from cell death: a role for AP-1. The Journal of Biological Chemistry. 279: 10931-8. PMID 14688262 DOI: 10.1074/Jbc.M311814200  0.615
2003 Young AP, Nagarajan R, Longmore GD. Mechanisms of transcriptional regulation by Rb-E2F segregate by biological pathway. Oncogene. 22: 7209-17. PMID 14562049 DOI: 10.1038/Sj.Onc.1206804  0.617
2003 Marie H, Pratt SJ, Betson M, Epple H, Kittler JT, Meek L, Moss SJ, Troyanovsky S, Attwell D, Longmore GD, Braga VM. The LIM protein Ajuba is recruited to cadherin-dependent cell junctions through an association with alpha-catenin. The Journal of Biological Chemistry. 278: 1220-8. PMID 12417594 DOI: 10.1074/Jbc.M205391200  0.766
2000 Kanungo J, Pratt SJ, Marie H, Longmore GD. Ajuba, a cytosolic LIM protein, shuttles into the nucleus and affects embryonal cell proliferation and fate decisions. Molecular Biology of the Cell. 11: 3299-313. PMID 11029037 DOI: 10.1091/Mbc.11.10.3299  0.474
2000 Wooten DK, Xie X, Bartos D, Busche RA, Longmore GD, Watowich SS. Cytokine signaling through Stat3 activates integrins, promotes adhesion, and induces growth arrest in the myeloid cell line 32D Journal of Biological Chemistry. 275: 26566-26575. PMID 10858439 DOI: 10.1074/Jbc.M003495200  0.421
1999 Goyal RK, Longmore GD. Abnormalities of cytokine receptor signalling contributing to diseases of red blood cell production Annals of Medicine. 31: 208-216. PMID 10442676  0.303
1999 Gaffen SL, Lai SY, Longmore GD, Liu KD, Goldsmith MA. Genetic evidence for an additional factor required for erythropoietin- induced signal transduction Blood. 94: 74-86. PMID 10381500 DOI: 10.1182/Blood.V94.1.74.413K36_74_86  0.339
1999 Goyal RK, Lin P, Kanungo J, Payne AS, Muslin AJ, Longmore GD. Ajuba, a novel LIM protein, interacts with Grb2, augments mitogen- activated protein kinase activity in fibroblasts, and promotes meiotic maturation of Xenopus oocytes in a Grb2- and Ras-dependent manner Molecular and Cellular Biology. 19: 4379-4389. PMID 10330178 DOI: 10.1128/Mcb.19.6.4379  0.413
1995 McArthur GA, Longmore GD, Klingler K, Johnson GR. Lineage-restricted recruitment of immature hematopoietic progenitor cells in response to Epo after normal hematopoietic cell transfection with EpoR Experimental Hematology. 23: 645-654. PMID 7601257  0.351
1994 Longmore GD, Pharr PN, Lodish HF. A constitutively activated erythropoietin receptor stimulates proliferation and contributes to transformation of multipotent, committed nonerythroid and erythroid progenitor cells Molecular and Cellular Biology. 14: 2266-2277. PMID 8139532 DOI: 10.1128/Mcb.14.4.2266  0.489
1994 Pharr PN, Ogawa M, Hofbauer A, Longmore GD. Expression of an activated erythropoietin or a colony-stimulating factor 1 receptor by pluripotent progenitors enhances colony formation but does not induce differentiation Proceedings of the National Academy of Sciences of the United States of America. 91: 7482-7486. PMID 8052607 DOI: 10.1073/Pnas.91.16.7482  0.36
1993 Youssoufian H, Longmore G, Neumann D, Yoshimura A, Lodish HF. Structure, function, and activation of the erythropoietin receptor Blood. 81: 2223-2236. PMID 8481505 DOI: 10.1182/Blood.V81.9.2223.2223  0.458
1993 Longmore GD, Pharr P, Neumann D, Lodish HF. Both megakaryocytopoiesis and erythropoiesis are induced in mice infected with a retrovirus expressing an oncogenic erythropoietin receptor Blood. 82: 2386-2395. PMID 8400289  0.463
1993 Longmore GD, Watowich SS, Hilton DJ, Lodish HF. The erythropoietin receptor: Its role in hematopoiesis and myeloproliferative diseases Journal of Cell Biology. 123: 1305-1308. PMID 8253831 DOI: 10.1083/Jcb.123.6.1305  0.354
1993 Pharr PN, Hankins D, Hofbauer A, Lodish HF, Longmore GD. Expression of a constitutively active erythropoietin receptor in primary hematopoietic progenitors abrogates erythropoietin dependence and enhances erythroid colony-forming unit, erythroid burst-forming unit, and granulocyte/macrophage progenitor growth Proceedings of the National Academy of Sciences of the United States of America. 90: 938-942. PMID 7679218  0.447
1993 Longmore G, Pharr P, Neumann D, Lodish H. Both megakaryocytopoiesis and erythropoiesis are induced in mice infected with a retrovirus expressing an oncogenic erythropoietin receptor [see comments] Blood. 82: 2386-2395. DOI: 10.1182/Blood.V82.8.2386.Bloodjournal8282386  0.525
1992 Lodish HF, Hilton D, Longmore G, Watowich SS, Yoshimura A. The erythropoietin receptor: Dimerization, activation, and tumorigenesis Cold Spring Harbor Symposia On Quantitative Biology. 57: 95-106. PMID 1339709 DOI: 10.1101/Sqb.1992.057.01.013  0.457
1992 Watowich SS, Yoshimura A, Longmore GD, Hilton DJ, Yoshimura Y, Lodish HF. Homodimerization and constitutive activation of the erythropoietin receptor Proceedings of the National Academy of Sciences of the United States of America. 89: 2140-2144. PMID 1312714 DOI: 10.1073/Pnas.89.6.2140  0.405
1991 Longmore GD, Lodish HF. An activating mutation in the murine erythropoietin receptor induces erythroleukemia in mice: A cytokine receptor superfamily oncogene Cell. 67: 1089-1102. PMID 1662116 DOI: 10.1016/0092-8674(91)90286-8  0.431
1990 Yoshimura A, Longmore G, Lodish HF. Point mutation in the exoplasmic domain of the erythropoietin receptor resulting in hormone-independent activation and tumorigenicity Nature. 348: 647-649. PMID 2174515 DOI: 10.1038/348647A0  0.502
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