| Year |
Citation |
Score |
| 2014 |
Reynolds AB, Kanner SB, Bouton AH, Schaller MD, Weed SA, Flynn DC, Parsons JT. SRChing for the substrates of Src. Oncogene. 33: 4537-47. PMID 24121272 DOI: 10.1038/Onc.2013.416 |
0.541 |
|
| 2013 |
Maninová M, Klímová Z, Parsons JT, Weber MJ, Iwanicki MP, Vomastek T. The reorientation of cell nucleus promotes the establishment of front-rear polarity in migrating fibroblasts. Journal of Molecular Biology. 425: 2039-55. PMID 23524135 DOI: 10.1016/J.Jmb.2013.02.034 |
0.702 |
|
| 2013 |
Lindberg JM, Adair SJ, Newhook TE, Kim A, Parsons JT, Bauer TW. Effect of trametinib in combination with panitumumab and trastuzumab on tumor growth in an orthotopic xenograft model of human pancreatic cancer. Journal of Clinical Oncology. 31: 190-190. DOI: 10.1200/Jco.2013.31.4_Suppl.190 |
0.318 |
|
| 2013 |
Lindberg JM, Newhook TE, Adair SJ, Cutchins CA, Kim A, Parsons JT, Bauer TW. Abstract 935: Inhibition of pancreatic cancer growth via MEK-targeted therapy is significantly enhanced by concomitant inhibition of EGFR and Her2. Cancer Research. 73: 935-935. DOI: 10.1158/1538-7445.Am2013-935 |
0.331 |
|
| 2012 |
Lindberg JM, Walters DM, Adair SJ, Cowan CR, Stokes JB, Borgman CA, Stelow EB, Lowrey BT, Chopivsky ME, Parsons JT, Bauer TW. Acquired resistance to combination therapy with lapatinib and MEK 1/2 inhibitor GSK1120212 in an in vivo murine model of pancreatic cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 208. PMID 27983148 DOI: 10.1200/Jco.2012.30.4_Suppl.208 |
0.351 |
|
| 2012 |
Tilghman RW, Blais EM, Cowan CR, Sherman NE, Grigera PR, Jeffery ED, Fox JW, Blackman BR, Tschumperlin DJ, Papin JA, Parsons JT. Matrix rigidity regulates cancer cell growth by modulating cellular metabolism and protein synthesis. Plos One. 7: e37231. PMID 22623999 DOI: 10.1371/Journal.Pone.0037231 |
0.381 |
|
| 2012 |
Grigera PR, Ma L, Borgman CA, Pinto AF, Sherman NE, Parsons JT, Fox JW. Mass spectrometric analysis identifies a cortactin-RCC2/TD60 interaction in mitotic cells Journal of Proteomics. 75: 2153-2159. PMID 22282019 DOI: 10.1016/j.jprot.2012.01.012 |
0.349 |
|
| 2011 |
Stokes JB, Adair SJ, Slack-Davis JK, Walters DM, Tilghman RW, Hershey ED, Lowrey B, Thomas KS, Bouton AH, Hwang RF, Stelow EB, Parsons JT, Bauer TW. Inhibition of focal adhesion kinase by PF-562,271 inhibits the growth and metastasis of pancreatic cancer concomitant with altering the tumor microenvironment. Molecular Cancer Therapeutics. 10: 2135-45. PMID 21903606 DOI: 10.1158/1535-7163.Mct-11-0261 |
0.37 |
|
| 2011 |
Walters DM, Cowan CR, Adair SJ, Borgman CA, Stokes JB, Stelow EB, Lowrey BT, Gilmer TM, Parsons JT, Bauer TW. Abstract 1592: Targeting proliferative signals in patient-derived pancreatic cancers propagated orthotopically in immunocompromised mice Cancer Research. 71: 1592-1592. DOI: 10.1158/1538-7445.Am2011-1592 |
0.312 |
|
| 2010 |
Tilghman RW, Cowan CR, Mih JD, Koryakina Y, Gioeli D, Slack-Davis JK, Blackman BR, Tschumperlin DJ, Parsons JT. Matrix rigidity regulates cancer cell growth and cellular phenotype Plos One. 5. PMID 20886123 DOI: 10.1371/Journal.Pone.0012905 |
0.364 |
|
| 2010 |
Parsons JT, Horwitz AR, Schwartz MA. Cell adhesion: integrating cytoskeletal dynamics and cellular tension. Nature Reviews. Molecular Cell Biology. 11: 633-43. PMID 20729930 DOI: 10.1038/Nrm2957 |
0.429 |
|
| 2010 |
Walters DM, Adair SJ, Stokes JB, Lowrey B, Parsons JT, Bauer TW. Abstract LB-241: Cancer-associated fibroblasts modulate growth- and metastasis-promoting pathways in human pancreatic cancer cells and augment orthotopic tumor growth in mice Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-241 |
0.336 |
|
| 2009 |
Slack-Davis JK, Hershey ED, Theodorescu D, Frierson HF, Parsons JT. Differential requirement for focal adhesion kinase signaling in cancer progression in the transgenic adenocarcinoma of mouse prostate model Molecular Cancer Therapeutics. 8: 2470-2477. PMID 19671741 DOI: 10.1158/1535-7163.Mct-09-0262 |
0.428 |
|
| 2009 |
Bernaciak TM, Zareno J, Parsons JT, Silva CM. A novel role for signal transducer and activator of transcription 5b (STAT5b) in β1-integrin-mediated human breast cancer cell migration Breast Cancer Research. 11. PMID 19630967 DOI: 10.1186/Bcr2341 |
0.339 |
|
| 2009 |
Petzold T, Orr AW, Hahn C, Jhaveri KA, Parsons JT, Schwartz MA. Focal adhesion kinase modulates activation of NF-kappaB by flow in endothelial cells. American Journal of Physiology. Cell Physiology. 297: C814-22. PMID 19587216 DOI: 10.1152/Ajpcell.00226.2009 |
0.384 |
|
| 2008 |
Vomastek T, Iwanicki MP, Burack WR, Tiwari D, Kumar D, Parsons JT, Weber MJ, Nandicoori VK. Extracellular signal-regulated kinase 2 (ERK2) phosphorylation sites and docking domain on the nuclear pore complex protein Tpr cooperatively regulate ERK2-Tpr interaction. Molecular and Cellular Biology. 28: 6954-66. PMID 18794356 DOI: 10.1128/Mcb.00925-08 |
0.761 |
|
| 2008 |
Sayers RL, Sundberg-Smith LJ, Rojas M, Hayasaka H, Parsons JT, Mack CP, Taylor JM. FRNK expression promotes smooth muscle cell maturation during vascular development and after vascular injury Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 2115-2122. PMID 18787183 DOI: 10.1161/Atvbaha.108.175455 |
0.358 |
|
| 2008 |
Iwanicki MP, Vomastek T, Tilghman RW, Martin KH, Banerjee J, Wedegaertner PB, Parsons JT. FAK, PDZ-RhoGEF and ROCKII cooperate to regulate adhesion movement and trailing-edge retraction in fibroblasts. Journal of Cell Science. 121: 895-905. PMID 18303050 DOI: 10.1242/Jcs.020941 |
0.729 |
|
| 2008 |
Tilghman RW, Parsons JT. Focal adhesion kinase as a regulator of cell tension in the progression of cancer Seminars in Cancer Biology. 18: 45-52. PMID 17928235 DOI: 10.1016/j.semcancer.2007.08.002 |
0.372 |
|
| 2007 |
Owen KA, Pixley FJ, Thomas KS, Vicente-Manzanares M, Ray BJ, Horwitz AF, Parsons JT, Beggs HE, Stanley ER, Bouton AH. Regulation of lamellipodial persistence, adhesion turnover, and motility in macrophages by focal adhesion kinase. The Journal of Cell Biology. 179: 1275-87. PMID 18070912 DOI: 10.1083/Jcb.200708093 |
0.47 |
|
| 2007 |
Mayhew MW, Jeffery ED, Sherman NE, Nelson K, Polefrone JM, Pratt SJ, Shabanowitz J, Parsons JT, Fox JW, Hunt DF, Horwitz AF. Identification of phosphorylation sites in betaPIX and PAK1. Journal of Cell Science. 120: 3911-8. PMID 17989089 DOI: 10.1242/Jcs.008177 |
0.34 |
|
| 2007 |
Vomastek T, Iwanicki MP, Schaeffer HJ, Tarcsafalvi A, Parsons JT, Weber MJ. RACK1 targets the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway to link integrin engagement with focal adhesion disassembly and cell motility. Molecular and Cellular Biology. 27: 8296-305. PMID 17908799 DOI: 10.1128/Mcb.00598-07 |
0.745 |
|
| 2007 |
Zhang X, Yuan Z, Zhang Y, Yong S, Salas-Burgos A, Koomen J, Olashaw N, Parsons JT, Yang XJ, Dent SR, Yao TP, Lane WS, Seto E. HDAC6 Modulates Cell Motility by Altering the Acetylation Level of Cortactin Molecular Cell. 27: 197-213. PMID 17643370 DOI: 10.1016/J.Molcel.2007.05.033 |
0.39 |
|
| 2007 |
Slack-Davis JK, Martin KH, Tilghman RW, Iwanicki M, Ung EJ, Autry C, Luzzio MJ, Cooper B, Kath JC, Roberts WG, Parsons JT. Cellular characterization of a novel focal adhesion kinase inhibitor Journal of Biological Chemistry. 282: 14845-14852. PMID 17395594 DOI: 10.1074/Jbc.M606695200 |
0.75 |
|
| 2007 |
Sayers RL, Rojas M, Kylander JE, Parsons JT, Mack CP, Taylor JM. A role for FRNK, a selectively expressed inhibitor of focal adhesion kinase (FAK), in vascular growth and development The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A67-C |
0.406 |
|
| 2006 |
Luxenburg C, Parsons JT, Addadi L, Geiger B. Involvement of the Src-cortactin pathway in podosome formation and turnover during polarization of cultured osteoclasts Journal of Cell Science. 119: 4878-4888. PMID 17105771 DOI: 10.1242/Jcs.03271 |
0.451 |
|
| 2005 |
Grigera PR, Jeffery ED, Martin KH, Shabanowitz J, Hunt DF, Parsons JT. FAK phosphorylation sites mapped by mass spectrometry. Journal of Cell Science. 118: 4931-5. PMID 16254240 DOI: 10.1242/Jcs.02696 |
0.501 |
|
| 2005 |
Hayasaka H, Simon K, Hershey ED, Masumoto KH, Parsons JT. FRNK, the autonomously expressed C-terminal region of focal adhesion kinase, is uniquely regulated in vascular smooth muscle: Analysis of expression in transgenic mice Journal of Cellular Biochemistry. 95: 1248-1263. PMID 15962314 DOI: 10.1002/Jcb.20501 |
0.345 |
|
| 2005 |
Tilghman RW, Slack-Davis JK, Sergina N, Martin KH, Iwanicki M, Hershey ED, Beggs HE, Reichardt LF, Parsons JT. Focal adhesion kinase is required for the spatial organization of the leading edge in migrating cells. Journal of Cell Science. 118: 2613-23. PMID 15914540 DOI: 10.1242/Jcs.02380 |
0.745 |
|
| 2005 |
Liu Y, Yerushalmi GM, Grigera PR, Parsons JT. Mislocalization or reduced expression of Arf GTPase-activating protein ASAP1 inhibits cell spreading and migration by influencing Arf1 GTPase cycling. The Journal of Biological Chemistry. 280: 8884-92. PMID 15632162 DOI: 10.1074/Jbc.M412200200 |
0.742 |
|
| 2004 |
Parsons SJ, Parsons JT. Src family kinases, key regulators of signal transduction. Oncogene. 23: 7906-9. PMID 15489908 DOI: 10.1038/sj.onc.1208160 |
0.348 |
|
| 2004 |
Bougnères L, Girardin SE, Weed SA, Karginov AV, Olivo-Marin JC, Parsons JT, Sansonetti PJ, Van Nhieu GT. Cortactin and Crk cooperate to trigger actin polymerization during Shigella invasion of epithelial cells. The Journal of Cell Biology. 166: 225-35. PMID 15263018 DOI: 10.1083/Jcb.200402073 |
0.779 |
|
| 2004 |
Eblen ST, Slack-Davis JK, Tarcsafalvi A, Parsons JT, Weber MJ, Catling AD. Mitogen-activated protein kinase feedback phosphorylation regulates MEK1 complex formation and activation during cellular adhesion. Molecular and Cellular Biology. 24: 2308-17. PMID 14993270 DOI: 10.1128/Mcb.24.6.2308-2317.2004 |
0.514 |
|
| 2004 |
Webb DJ, Donais K, Whitmore LA, Thomas SM, Turner CE, Parsons JT, Horwitz AF. FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly. Nature Cell Biology. 6: 154-61. PMID 14743221 DOI: 10.1038/Ncb1094 |
0.527 |
|
| 2004 |
Schaller MD, Parsons JT. Focal adhesion kinase: an integrin-linked protein tyrosine kinase. Trends in Cell Biology. 3: 258-62. PMID 14731743 DOI: 10.1016/0962-8924(93)90053-4 |
0.643 |
|
| 2004 |
Schaller MD, Parsons JT. Focal adhesion kinase: an integrin-linked protein tyrosine kinase. Trends in Cell Biology. 3: 258-62. PMID 14731743 DOI: 10.1016/0962-8924(93)90053-4 |
0.643 |
|
| 2004 |
Slack-Davis JK, Parsons JT. Emerging views of integrin signaling: Implications for prostate cancer Journal of Cellular Biochemistry. 91: 41-46. PMID 14689580 DOI: 10.1002/Jcb.10665 |
0.362 |
|
| 2003 |
Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons JT, Horwitz AR. Cell migration: integrating signals from front to back. Science (New York, N.Y.). 302: 1704-9. PMID 14657486 DOI: 10.1126/Science.1092053 |
0.368 |
|
| 2003 |
Head JA, Jiang D, Li M, Zorn LJ, Schaefer EM, Parsons JT, Weed SA. Cortactin tyrosine phosphorylation requires Rac1 activity and association with the cortical actin cytoskeleton Molecular Biology of the Cell. 14: 3216-3229. PMID 12925758 DOI: 10.1091/mbc.E02-11-0753 |
0.455 |
|
| 2003 |
Hou P, Estrada L, Kinley AW, Parsons JT, Vojtek AB, Gorski JL. Fgd1, the Cdc42 GEF responsible for Faciogenital Dysplasia, directly interacts with cortactin and mAbp1 to modulate cell shape Human Molecular Genetics. 12: 1981-1993. PMID 12913069 DOI: 10.1093/Hmg/Ddg209 |
0.468 |
|
| 2003 |
Slack-Davis JK, Eblen ST, Zecevic M, Boerner SA, Tarcsafalvi A, Diaz HB, Marshall MS, Weber MJ, Parsons JT, Catling AD. PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation. The Journal of Cell Biology. 162: 281-91. PMID 12876277 DOI: 10.1083/Jcb.200212141 |
0.41 |
|
| 2003 |
Parsons JT. Focal adhesion kinase: The first ten years Journal of Cell Science. 116: 1409-1416. PMID 12640026 DOI: 10.1242/jcs.00373 |
0.474 |
|
| 2003 |
Kinley AW, Weed SA, Weaver AM, Karginov AV, Bissonette E, Cooper JA, Parsons JT. Cortactin interacts with WIP in regulating Arp2/3 activation and membrane protrusion. Current Biology : Cb. 13: 384-93. PMID 12620186 DOI: 10.1016/S0960-9822(03)00107-6 |
0.727 |
|
| 2002 |
Schafer DA, Weed SA, Binns D, Karginov AV, Parsons JT, Cooper JA. Dynamin2 and cortactin regulate actin assembly and filament organization. Current Biology : Cb. 12: 1852-7. PMID 12419186 DOI: 10.1016/S0960-9822(02)01228-9 |
0.713 |
|
| 2002 |
Rovin JD, Frierson HF, Ledinh W, Parsons JT, Adams RB. Expression of focal adhesion kinase in normal and pathologic human prostate tissues. The Prostate. 53: 124-32. PMID 12242727 DOI: 10.1002/Pros.10114 |
0.333 |
|
| 2002 |
Weaver AM, Heuser JE, Karginov AV, Lee WL, Parsons JT, Cooper JA. Interaction of cortactin and N-WASp with Arp2/3 complex. Current Biology : Cb. 12: 1270-8. PMID 12176354 DOI: 10.1016/S0960-9822(02)01035-7 |
0.693 |
|
| 2002 |
Liu Y, Loijens JC, Martin KH, Karginov AV, Parsons JT. The association of ASAP1, an ADP ribosylation factor-GTPase activating protein, with focal adhesion kinase contributes to the process of focal adhesion assembly. Molecular Biology of the Cell. 13: 2147-56. PMID 12058076 DOI: 10.1091/Mbc.E02-01-0018 |
0.811 |
|
| 2002 |
Webb DJ, Parsons JT, Horwitz AF. Adhesion assembly, disassembly and turnover in migrating cells - Over and over and over again Nature Cell Biology. 4: E97-E100. PMID 11944043 DOI: 10.1038/Ncb0402-E97 |
0.409 |
|
| 2002 |
Martin KH, Boerner SA, Parsons JT. Regulation of focal adhesion targeting and inhibitory functions of the FAK related protein FRNK using a novel estrogen receptor "switch". Cell Motility and the Cytoskeleton. 51: 76-88. PMID 11921165 DOI: 10.1002/cm.10018 |
0.37 |
|
| 2001 |
Haskell MD, Slack JK, Parsons JT, Parsons SJ. c-Src tyrosine phosphorylation of epidermal growth factor receptor, P190 RhoGAP, and focal adhesion kinase regulates diverse cellular processes Chemical Reviews. 101: 2425-2440. PMID 11749381 DOI: 10.1021/Cr0002341 |
0.442 |
|
| 2001 |
Weed SA, Parsons JT. Cortactin: Coupling membrane dynamics to cortical actin assembly Oncogene. 20: 6418-6434. PMID 11607842 DOI: 10.1038/Sj.Onc.1204783 |
0.471 |
|
| 2001 |
Fresu M, Bianchi M, Parsons JT, Villa-Moruzzi E. Cell-cycle-dependent association of protein phosphatase 1 and focal adhesion kinase Biochemical Journal. 358: 407-414. PMID 11513739 DOI: 10.1042/Bj3580407 |
0.507 |
|
| 2001 |
Slack JK, Adams RB, Rovin JD, Bissonette EA, Stoker CE, Parsons JT. Alterations in the focal adhesion kinase/Src signal transduction pathway correlate with increased migratory capacity of prostate carcinoma cells. Oncogene. 20: 1152-63. PMID 11313859 DOI: 10.1038/Sj.Onc.1204208 |
0.517 |
|
| 2001 |
Weaver AM, Karginov AV, Kinley AW, Weed SA, Li Y, Parsons JT, Cooper JA. Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation. Current Biology : Cb. 11: 370-4. PMID 11267876 DOI: 10.1016/S0960-9822(01)00098-7 |
0.708 |
|
| 2001 |
Ma A, Richardson A, Schaefer EM, Parsons JT. Serine phosphorylation of focal adhesion kinase in interphase and mitosis: A possible role in modulating binding to p130Cas Molecular Biology of the Cell. 12: 1-12. PMID 11160818 DOI: 10.1091/Mbc.12.1.1 |
0.676 |
|
| 2000 |
Parsons JT, Martin KH, Slack JK, Taylor JM, Weed SA. Focal Adhesion Kinase: A regulator of focal adhesion dynamics and cell movement Oncogene. 19: 5606-5613. PMID 11114741 DOI: 10.1038/Sj.Onc.1203877 |
0.537 |
|
| 2000 |
Weed SA, Karginov AV, Schafer DA, Weaver AM, Kinley AW, Cooper JA, Parsons JT. Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex. The Journal of Cell Biology. 151: 29-40. PMID 11018051 DOI: 10.1083/Jcb.151.1.29 |
0.721 |
|
| 2000 |
Longenecker KL, Zhang B, Derewenda U, Sheffield PJ, Dauter Z, Parsons JT, Zheng Y, Derewenda ZS. Structure of the BH domain from Graf and its implications for Rho GTPase recognition Journal of Biological Chemistry. 275: 38605-38610. PMID 10982819 DOI: 10.1074/jbc.M007574200 |
0.325 |
|
| 2000 |
Taylor JM, Rovin JD, Parsons JT. A role for focal adhesion kinase in phenylephrine-induced hypertrophy of rat ventricular cardiomyocytes Journal of Biological Chemistry. 275: 19250-19257. PMID 10749882 DOI: 10.1074/Jbc.M909099199 |
0.506 |
|
| 1999 |
Horwitz AR, Parsons JT. Cell migration--movin' on. Science (New York, N.Y.). 286: 1102-3. PMID 10610524 DOI: 10.1126/Science.286.5442.1102 |
0.389 |
|
| 1999 |
Schaller MD, Hildebrand JD, Parsons JT. Complex formation with focal adhesion kinase: A mechanism to regulate activity and subcellular localization of Src kinases Molecular Biology of the Cell. 10: 3489-3505. PMID 10512882 DOI: 10.1091/Mbc.10.10.3489 |
0.682 |
|
| 1999 |
Slack JK, Catling AD, Eblen ST, Weber MJ, Parsons JT. c-Raf-mediated inhibition of epidermal growth factor-stimulated cell migration. The Journal of Biological Chemistry. 274: 27177-84. PMID 10480934 DOI: 10.1074/jbc.274.38.27177 |
0.313 |
|
| 1999 |
Nolan K, Lacoste J, Parsons JT. Regulated expression of focal adhesion kinase-related nonkinase, the autonomously expressed C-terminal domain of focal adhesion kinase. Molecular and Cellular Biology. 19: 6120-9. PMID 10454559 DOI: 10.1128/Mcb.19.9.6120 |
0.479 |
|
| 1999 |
Taylor JM, Macklem MM, Parsons JT. Cytoskeletal changes induced by GRAF, the GTPase regulator associated with focal adhesion kinase, are mediated by Rho Journal of Cell Science. 112: 231-242. PMID 9858476 |
0.388 |
|
| 1998 |
Lacoste J, Ma A, Parsons JT. Assay and purification and focal adhesion kinase. Methods in Enzymology. 298: 89-102. PMID 9751874 DOI: 10.1016/S0076-6879(98)98011-9 |
0.368 |
|
| 1998 |
Du Y, Weed SA, Xiong WC, Marshall TD, Parsons JT. Identification of a novel cortactin SH3 domain-binding protein and its localization to growth cones of cultured neurons. Molecular and Cellular Biology. 18: 5838-51. PMID 9742101 DOI: 10.1128/Mcb.18.10.5838 |
0.433 |
|
| 1998 |
Xiong WC, Macklem M, Parsons JT. Expression and characterization of splice variants of PYK2, a focal adhesion kinase-related protein. Journal of Cell Science. 111: 1981-91. PMID 9645946 |
0.42 |
|
| 1998 |
Taylor JM, Hildebrand JD, Mack CP, Cox ME, Parsons JT. Characterization of Graf, the GTPase-activating protein for Rho associated with focal adhesion kinase. Phosphorylation and possible regulation by mitogen-activated protein kinase Journal of Biological Chemistry. 273: 8063-8070. PMID 9525907 DOI: 10.1074/Jbc.273.14.8063 |
0.531 |
|
| 1998 |
Sheffield PJ, Derewenda U, Taylor J, Parsons JT, Derewenda ZS. Expression, purification and crystallization of a novel gtpase activating protein (GAP) associated with focal adhesion kinase Faseb Journal. 12: A1368. |
0.323 |
|
| 1997 |
Richardson A, Malik RK, Hildebrand JD, Parsons JT. Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: A role for paxillin tyrosine phosphorylation Molecular and Cellular Biology. 17: 6906-6914. PMID 9372922 DOI: 10.1128/MCB.17.12.6906 |
0.482 |
|
| 1997 |
Xiong WC, Parsons JT. Induction of apoptosis after expression of PYK2, a tyrosine kinase structurally related to focal adhesion kinase Journal of Cell Biology. 139: 529-539. PMID 9334354 DOI: 10.1083/Jcb.139.2.529 |
0.53 |
|
| 1997 |
Richardson A, Shannon JD, Adams RB, Schaller MD, Parsons J. Identification of integrin-stimulated sites of serine phosphorylation in FRNK, the separately expressed C-terminal domain of focal adhesion kinase: a potential role for protein kinase A. The Biochemical Journal. 324: 141-9. PMID 9164850 DOI: 10.1042/Bj3240141 |
0.654 |
|
| 1997 |
Parsons JT, Parsons SJ. Src family protein tyrosine kinases: Cooperating with growth factor and adhesion signaling pathways Current Opinion in Cell Biology. 9: 187-192. PMID 9069259 DOI: 10.1016/S0955-0674(97)80062-2 |
0.47 |
|
| 1996 |
Malik RK, Parsons JT. Integrin-dependent activation of the p70 ribosomal S6 kinase signaling pathway Journal of Biological Chemistry. 271: 29785-29791. PMID 8939916 DOI: 10.1074/Jbc.271.47.29785 |
0.529 |
|
| 1996 |
Parsons JT. Integrin-mediated signalling: Regulation by protein tyrosine kinases and small GTP-binding proteins Current Opinion in Cell Biology. 8: 146-152. PMID 8791417 DOI: 10.1016/S0955-0674(96)80059-7 |
0.515 |
|
| 1996 |
Malik RK, Parsons JT. Integrin-mediated signaling in normal and malignant cells: A role of protein tyrosine kinases Biochimica Et Biophysica Acta - Reviews On Cancer. 1287: 73-76. PMID 8672530 DOI: 10.1016/0304-419X(96)00008-X |
0.508 |
|
| 1996 |
Harte MT, Hildebrand JD, Burnham MR, Bouton AH, Parsons JT. p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase. The Journal of Biological Chemistry. 271: 13649-55. PMID 8662921 DOI: 10.1074/Jbc.271.23.13649 |
0.336 |
|
| 1996 |
Hildebrand JD, Taylor JM, Parsons JT. An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase. Molecular and Cellular Biology. 16: 3169-78. PMID 8649427 DOI: 10.1128/MCB.16.6.3169 |
0.477 |
|
| 1996 |
Richardson A, Parsons JT. A mechanism for regulation of the adhesion-associated protein tyrosine kinase pp125FAK Nature. 380: 538-540. PMID 8606775 DOI: 10.1038/380538A0 |
0.556 |
|
| 1996 |
Malik RK, Parsons JT. REQUIREMENT FOR pp125 FOCAL ADHESION KINASE AND c-SRC IN THE INTEGRIN-DEPENDENT ACTIVATION OF p70/p85 RIBOSOMAL S6 KINASE. ▴ 936 Pediatric Research. 39: 158-158. DOI: 10.1203/00006450-199604001-00958 |
0.443 |
|
| 1995 |
Richardson A, Parsons JT. Signal transduction through integrins: A central role for focal adhesion kinase ? Bioessays. 17: 229-236. PMID 7748177 DOI: 10.1002/Bies.950170309 |
0.519 |
|
| 1995 |
Schaller MD, Otey CA, Hildebrand JD, Parsons JT. Focal adhesion kinase and paxillin bind to peptides mimicking β integrin cytoplasmic domains Journal of Cell Biology. 130: 1181-1187. PMID 7657702 DOI: 10.1083/Jcb.130.5.1181 |
0.633 |
|
| 1995 |
Chen HC, Appeddu PA, Parsons JT, Hildebrand JD, Schaller MD, Guan JL. Interaction of focal adhesion kinase with cytoskeletal protein talin Journal of Biological Chemistry. 270: 16995-16999. PMID 7622520 DOI: 10.1074/Jbc.270.28.16995 |
0.7 |
|
| 1995 |
Hildebrand JD, Schaller MD, Parsons JT. Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase Molecular Biology of the Cell. 6: 637-647. PMID 7579684 DOI: 10.1091/Mbc.6.6.637 |
0.679 |
|
| 1995 |
Petch LA, Bockholt SM, Bouton A, Parsons JT, Burridge K. Adhesion-induced tyrosine phosphorylation of the p130 src substrate. Journal of Cell Science. 108: 1371-9. PMID 7542255 |
0.405 |
|
| 1995 |
Schaller MD, Parsons JT. pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk Molecular and Cellular Biology. 15: 2635-2645. PMID 7537852 DOI: 10.1128/Mcb.15.5.2635 |
0.643 |
|
| 1994 |
Parsons JT, Schaller MD, Hildebrand J, Leu TH, Richardson A, Otey C. Focal adhesion kinase: structure and signalling. Journal of Cell Science. Supplement. 18: 109-13. PMID 7883785 DOI: 10.1242/Jcs.1994.Supplement_18.16 |
0.626 |
|
| 1994 |
Marengere LE, Songyang Z, Gish GD, Schaller MD, Parsons JT, Stern MJ, Cantley LC, Pawson T. SH2 domain specificity and activity modified by a single residue. Nature. 369: 502-5. PMID 7515480 DOI: 10.1038/369502A0 |
0.606 |
|
| 1994 |
Faris M, Gaskin F, Parsons JT, Fu SM. CD40 signaling pathway: Anti-CD40 monoclonal antibody induces rapid dephosphorylation and phosphorylation of tyrosine-phosphorylated proteins including protein tyrosine kinase Lyn, Fyn, and Syk and the appearance of a 28-kD tyrosine phosphorylated protein Journal of Experimental Medicine. 179: 1923-1931. PMID 7515102 |
0.307 |
|
| 1994 |
Shattil SJ, Haimovich B, Cunningham M, Lipfert L, Parsons JT, Ginsberg MH, Brugge JS. Tyrosine phosphorylation of pp125FAK in platelets requires coordinated signaling through integrin and agonist receptors Journal of Biological Chemistry. 269: 14738-14745. PMID 7514181 |
0.322 |
|
| 1994 |
Schaller MD, Hildebrand JD, Shannon JD, Fox JW, Vines RR, Parsons JT. Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src Molecular and Cellular Biology. 14: 1680-1688. PMID 7509446 DOI: 10.1128/Mcb.14.3.1680 |
0.652 |
|
| 1994 |
Cobb BS, Schaller MD, Leu TH, Parsons JT. Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK. Molecular and Cellular Biology. 14: 147-55. PMID 7505391 DOI: 10.1128/Mcb.14.1.147 |
0.653 |
|
| 1993 |
Parsons JT, Parsons SJ. Protein-tyrosine kinases, oncogenes, and cancer Important Advances in Oncology. 3-17. PMID 8505055 |
0.309 |
|
| 1993 |
Schaller MD, Bouton AH, Flynn DC, Parsons JT. Identification and characterization of novel substrates for protein tyrosine kinases Progress in Nucleic Acid Research and Molecular Biology. 44: 205-227. PMID 8434124 DOI: 10.1016/S0079-6603(08)60221-4 |
0.645 |
|
| 1993 |
Schaller MD, Borgman CA, Parsons JT. Autonomous Expression of a Noncatalytic Domain of the Focal Adhesion-Associated Protein Tyrosine Kinase pp125FAK Molecular and Cellular Biology. 13: 785-791. PMID 8423801 DOI: 10.1128/Mcb.13.2.785 |
0.656 |
|
| 1993 |
Turner CE, Schaller MD, Parsons JT. Tyrosine phosphorylation of the focal adhesion kinase pp125FAK during development: Relation to paxillin Journal of Cell Science. 105: 637-645. PMID 8408291 |
0.627 |
|
| 1993 |
Flynn DC, Leu TH, Reynolds AB, Parsons JT. Identification and sequence analysis of cDNAs encoding a 110-kilodalton actin filament-associated pp60src substrate. Molecular and Cellular Biology. 13: 7892-900. PMID 8247004 DOI: 10.1128/mcb.13.12.7892-7900.1993 |
0.384 |
|
| 1993 |
Hildebrand JD, Schaller MD, Parsons JT. Identification of sequences required for the efficient localization of the Focal Adhesion Kinase, pp125FAK, to cellular focal adhesions Journal of Cell Biology. 123: 993-1005. PMID 8227154 DOI: 10.1083/Jcb.123.4.993 |
0.65 |
|
| 1993 |
Cobb BS, Parsons JT. Regulation of the cellular src protein tyrosine kinase: Interactions of the carboxyl terminal sequences residing between the kinase domain and tyrosine-527 Oncogene. 8: 2897-2903. PMID 7692368 |
0.391 |
|
| 1993 |
Wu H, Parsons JT. Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-Binding protein enriched in the cell cortex Journal of Cell Biology. 120: 1417-1426. PMID 7680654 DOI: 10.1083/JCB.120.6.1417 |
0.378 |
|
| 1992 |
Schaller MD, Borgman CA, Cobb BS, Vines RR, Reynolds AB, Parsons JT. pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions. Proceedings of the National Academy of Sciences of the United States of America. 89: 5192-6. PMID 1594631 DOI: 10.1073/Pnas.89.11.5192 |
0.644 |
|
| 1992 |
Kornberg L, Earp HS, Parsons JT, Schaller M, Juliano RL. Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase. The Journal of Biological Chemistry. 267: 23439-42. PMID 1429685 |
0.39 |
|
| 1992 |
Lipfert L, Haimovich B, Schaller MD, Cobb BS, Parsons JT, Brugge JS. Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets Journal of Cell Biology. 119: 905-912. PMID 1385445 DOI: 10.1083/Jcb.119.4.905 |
0.614 |
|
| 1992 |
Flynn DC, Schaller MD, Parsons JT. Tyrosine phosphorylation of a 120 000 dalton membrane-associated protein by the neural form of pp60c-src pp60c-src+ Oncogene. 7: 579-583. PMID 1372401 |
0.625 |
|
| 1992 |
Maa MC, Wilson LK, Moyers JS, Vines RR, Parsons JT, Parsons SJ. Identification and characterization of a cytoskeleton-associated, epidermal growth factor sensitive pp60c-src substrate Oncogene. 7: 2429-2438. PMID 1281304 |
0.343 |
|
| 1992 |
Kornberg L, Earp H, Parsons J, Schaller M, Juliano R. Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase. Journal of Biological Chemistry. 267: 23439-23442. DOI: 10.1016/s0021-9258(18)35853-8 |
0.366 |
|
| 1992 |
Ely CM, Parsons SJ, Parsons JT. Immunological methods for the detection of phosphotyrosine-containing proteins in neural tissues Neuroprotocols. 1: 177-184. DOI: 10.1016/1058-6741(92)90026-T |
0.421 |
|
| 1991 |
Cobb BS, Payne DM, Reynolds AB, Parsons JT. Regulation of the oncogenic activity of the cellular src protein requires the correct spacing between the kinase domain and the C-terminal phosphorylated tyrosine (Tyr-527). Molecular and Cellular Biology. 11: 5832-8. PMID 1719372 DOI: 10.1128/Mcb.11.12.5832 |
0.365 |
|
| 1991 |
Kanner SB, Reynolds AB, Wang HC, Vines RR, Parsons JT. The SH2 and SH3 domains of pp60src direct stable association with tyrosine phosphorylated proteins p130 and p110. The Embo Journal. 10: 1689-98. PMID 1710979 DOI: 10.1002/J.1460-2075.1991.Tb07693.X |
0.322 |
|
| 1991 |
Bouton AH, Kanner SB, Vines RR, Parsons JT. Tyrosine phosphorylation of three cellular proteins correlates with transformation of rat 1 cells by pp60(src) Molecular Carcinogenesis. 4: 145-152. PMID 1710464 |
0.409 |
|
| 1991 |
Bouton AH, Kanner SB, Vines RR, Wang HCR, Gibbs JB, Parsons JT. Transformation by pp6Qsrc or Stimulation of Cells with Epidermal Growth Factor Induces the Stable Association of Tyrosine-Phosphorylated Cellular Proteins with GTPase-Activating Protein Molecular and Cellular Biology. 11: 945-953. PMID 1703633 DOI: 10.1128/Mcb.11.2.945 |
0.346 |
|
| 1991 |
Kanner SB, Reynolds AB, Parsons JT. Tyrosine phosphorylation of a 120-kilodalton pp60src substrate upon epidermal growth factor and platelet-derived growth factor receptor stimulation and in polyomavirus middle-T-antigen-transformed cells. Molecular and Cellular Biology. 11: 713-20. PMID 1703631 DOI: 10.1128/Mcb.11.2.713 |
0.386 |
|
| 1989 |
Reynolds AB, Kanner SB, Wang HCR, Parsons JT. Stable association of activated pp60(src) with two tyrosine-phosphorylated cellular proteins Molecular and Cellular Biology. 9: 3951-3958. PMID 2476666 DOI: 10.1128/Mcb.9.9.3951 |
0.377 |
|
| 1989 |
Wilson LK, Luttrell DK, Parsons JT, Parsons SJ. pp60(c-src) tyrosine kinase, myristylation, and modulatory domains are required for enhanced mitogenic responsiveness to epidermal growth factor seen in cells overexpressing c-src Molecular and Cellular Biology. 9: 1536-1544. PMID 2471064 DOI: 10.1128/Mcb.9.4.1536 |
0.314 |
|
| 1989 |
Reynolds AB, Roesel DJ, Kanner SB, Parsons JT. Transformation-specific tyrosine phosphorylation of a novel cellular protein in chicken cells expressing oncogenic variants of the avian cellular src gene Molecular and Cellular Biology. 9: 629-638. PMID 2469003 DOI: 10.1128/Mcb.9.2.629 |
0.382 |
|
| 1989 |
Kanner SB, Gilmer TM, Reynolds AB, Parsons JT. Novel tyrosine phosphorylations accompany the activation of pp60(c-src) during chemical carcinogenesis Oncogene. 4: 295-300. PMID 2468123 |
0.356 |
|
| 1988 |
Potts WM, Reynolds AB, Lansing TJ, Parsons JT. Activation of pp60(c-src) transforming potential by mutations altering the structure of an amino terminal domain containing residues 90-95 Oncogene Research. 3: 343-355. PMID 2465527 |
0.325 |
|
| 1988 |
Kanner SB, Parsons SJ, Parsons JT, Gilmer TM. Activation of pp60(c-src) tyrosine kinase specific activity in tumor-derived Syrian hamster embryo cells Oncogene. 2: 327-335. PMID 2452399 |
0.338 |
|
| 1987 |
Raymond VW, Parsons JT. Identification of an amino terminal domain required for the transforming activity of the Rous sarcoma virus src protein. Virology. 160: 400-10. PMID 3660586 DOI: 10.1016/0042-6822(87)90011-0 |
0.413 |
|
| 1987 |
Taparowsky EJ, Heaney ML, Parsons JT. Oncogene-mediated multistep transformation of C3H10T1/2 cells Cancer Research. 47: 4125-4129. PMID 3300959 |
0.583 |
|
| 1987 |
Reynolds AB, Vila J, Lansing TJ, Potts WM, Weber MJ, Parsons JT. Activation of the oncogenic potential of the avian cellular src protein by specific structural alteration of the carboxy terminus Embo Journal. 6: 2359-2364. PMID 2822389 DOI: 10.1002/J.1460-2075.1987.Tb02512.X |
0.363 |
|
| 1987 |
McCarley DJ, Parsons JT, Benjamin DC, Parsons SJ. Inhibition of the tyrosine kinase activity of v-src, v-fgr, and v-yes gene products by a monoclonal antibody which binds both amino and carboxy peptide fragments of pp60(v-src) Journal of Virology. 61: 1927-1937. PMID 2437325 |
0.305 |
|
| 1986 |
Morgan JH, Parsons JT. Characterization of c-myc proteins from avian bursal lymphoma cell lines Virology. 150: 178-186. PMID 3513434 DOI: 10.1016/0042-6822(86)90277-1 |
0.363 |
|
| 1986 |
Parsons JT, Wilkerson V, Parsons SJ. Structural and functional motifs of the Rous sarcoma virus src protein Gene Amplification and Analysis. 4: 1-19. PMID 2851527 |
0.306 |
|
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