Heqing Huang, Ph.D. - Publications

Affiliations: 
2002 University of Iowa, Iowa City, IA 
Area:
Environmental Engineering

61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Xiao H, Sun X, Liu R, Chen Z, Lin Z, Yang Y, Zhang M, Liu P, Quan S, Huang H. Gentiopicroside activates the bile acid receptor Gpbar1 (TGR5) to repress NF-kappaB pathway and ameliorate diabetic nephropathy (original article). Pharmacological Research. 104559. PMID 31759089 DOI: 10.1016/j.phrs.2019.104559  0.36
2019 Chen Z, Sun X, Chen Q, Lan T, Huang K, Xiao H, Lin Z, Yang Y, Liu P, Huang H. Connexin32 ameliorates renal fibrosis in diabetic mice by promoting K48-linked Nox4 polyubiquitination and degradation via the inhibition of Smurf1 expression. British Journal of Pharmacology. PMID 31465542 DOI: 10.1111/bph.14853  0.36
2019 Chen L, Sun X, Xiao H, Xu F, Yang Y, Lin Z, Chen Z, Quan S, Huang H. PAQR3 regulates phosphorylation of FoxO1 in insulin-resistant HepG2 cells via NF-κB signaling pathway. Experimental Cell Research. PMID 31095939 DOI: 10.1016/j.yexcr.2019.04.031  0.36
2019 Xu F, Xiao H, Liu R, Yang Y, Zhang M, Chen L, Chen Z, Liu P, Huang H. Paeonol Ameliorates Glucose and Lipid Metabolism in Experimental Diabetes by Activating Akt. Frontiers in Pharmacology. 10: 261. PMID 30941042 DOI: 10.3389/fphar.2019.00261  0.36
2018 Zou Y, Chen Z, Li J, Gong W, Zhang L, Xu F, Chen L, Liu P, Huang H. Progestin and AdipoQ Receptor 3 Upregulates Fibronectin and Intercellular Adhesion Molecule-1 in Glomerular Mesangial Cells Activating NF-κB Signaling Pathway Under High Glucose Conditions. Frontiers in Endocrinology. 9: 275. PMID 29930535 DOI: 10.3389/fendo.2018.00275  0.36
2018 Zhang L, Chen Z, Gong W, Zou Y, Xu F, Chen L, Huang H. Paeonol Ameliorates Diabetic Renal Fibrosis Through Promoting the Activation of the Nrf2/ARE Pathway via Up-Regulating Sirt1. Frontiers in Pharmacology. 9: 512. PMID 29867511 DOI: 10.3389/fphar.2018.00512  0.36
2017 Gong W, Chen Z, Zou Y, Zhang L, Huang J, Liu P, Huang H. CKIP-1 affects the polyubiquitination of Nrf2 and Keap1 via mediating Smurf1 to resist HG-induced renal fibrosis in GMCs and diabetic mice kidneys. Free Radical Biology & Medicine. PMID 29248720 DOI: 10.1016/j.freeradbiomed.2017.12.013  0.36
2017 Chen Z, Chen Q, Huang J, Gong W, Zou Y, Zhang L, Liu P, Huang H. CK2α promotes advanced glycation end products-induced expressions of fibronectin and intercellular adhesion molecule-1 via activating MRTF-A in glomerular mesangial cells. Biochemical Pharmacology. PMID 29223351 DOI: 10.1016/j.bcp.2017.12.002  0.36
2017 Huang J, Li J, Chen Z, Li J, Chen Q, Gong W, Liu P, Huang H. Sphingosine kinase 1 mediates diabetic renal fibrosis via NF-κB signaling pathway: involvement of CK2α. Oncotarget. 8: 88988-89004. PMID 29179493 DOI: 10.18632/oncotarget.21640  0.36
2017 Chen C, Gong W, Li C, Xiong F, Wang S, Huang J, Wang Y, Chen Z, Chen Q, Liu P, Lan T, Huang H. Sphingosine kinase 1 mediates AGEs-induced fibronectin upregulation in diabetic nephropathy. Oncotarget. 8: 78660-78676. PMID 29108256 DOI: 10.18632/oncotarget.20205  0.36
2017 Chen Q, Huang J, Gong W, Chen Z, Huang J, Liu P, Huang H. MRTF-A mediated FN and ICAM-1 expression in AGEs-induced rat glomerular mesangial cells via activating STAT5. Molecular and Cellular Endocrinology. PMID 28712960 DOI: 10.1016/j.mce.2017.07.014  0.36
2017 Gong W, Li J, Chen Z, Huang J, Chen Q, Cai W, Liu P, Huang H. Polydatin promotes Nrf2-ARE anti-oxidative pathway through activating CKIP-1 to resist HG-induced up-regulation of FN and ICAM-1 in GMCs and diabetic mice kidneys. Free Radical Biology & Medicine. PMID 28286065 DOI: 10.1016/j.freeradbiomed.2017.03.003  0.36
2017 Huang J, Chen Z, Li J, Chen Q, Li J, Gong W, Huang J, Liu P, Huang H. Protein kinase CK2α catalytic subunit ameliorates diabetic renal inflammatory fibrosis via NF-κB signaling pathway. Biochemical Pharmacology. PMID 28237649 DOI: 10.1016/j.bcp.2017.02.016  0.36
2017 Zhu X, Huang H, Zhang Y, Zhang H, Hou L, Zhang Z. Cit/CuS@Fe3O4-based and enzyme-responsive magnetic nanoparticles for tumor chemotherapy, photothermal, and photodynamic therapy. Journal of Biomaterials Applications. 31: 1010-1025. PMID 28178904 DOI: 10.1177/0885328216676159  0.36
2016 Huang J, Gong W, Chen Z, Huang J, Chen Q, Huang H, Zhao C. Emodin self-emulsifying platform ameliorates the expression of FN, ICAM-1 and TGF-β1 in AGEs-induced glomerular mesangial cells by promoting absorption. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. PMID 27988328 DOI: 10.1016/j.ejps.2016.12.012  0.36
2016 Chen Z, Xie X, Huang J, Gong W, Zhu X, Chen Q, Huang J, Huang H. Connexin43 regulates high glucose-induced expression of fibronectin, ICAM-1 and TGF-β1 via Nrf2/ARE pathway in glomerular mesangial cells. Free Radical Biology & Medicine. PMID 27840317 DOI: 10.1016/j.freeradbiomed.2016.11.015  0.36
2016 Gong W, Chen C, Xiong F, Yang Z, Wang Y, Huang J, Liu P, Huang H. CKIP-1 ameliorates high glucose-induced expression of fibronectin and intercellular cell adhesion molecule-1 by activating the Nrf2/ARE pathway in glomerular mesangial cells. Biochemical Pharmacology. PMID 27481061 DOI: 10.1016/j.bcp.2016.07.019  0.36
2016 Xiong F, Li X, Yang Z, Wang Y, Gong W, Huang J, Chen C, Liu P, Huang H. TGR5 suppresses high glucose-induced upregulation of fibronectin and transforming growth factor-β1 in rat glomerular mesangial cells by inhibiting RhoA/ROCK signaling. Endocrine. PMID 27470217 DOI: 10.1007/s12020-016-1032-4  0.36
2016 Wang S, Yang Z, Xiong F, Chen C, Chao X, Huang J, Huang H. Betulinic acid ameliorates experimental diabetic-induced renal inflammation and fibrosis via inhibiting the activation of NF-κB signaling pathway. Molecular and Cellular Endocrinology. PMID 27364889 DOI: 10.1016/j.mce.2016.06.019  0.36
2016 Yang Z, Xiong F, Wang Y, Gong W, Huang J, Chen C, Liu P, Huang H. TGR5 activation suppressed S1P/S1P2 signaling and resisted high glucose-induced fibrosis in glomerular mesangial cells. Pharmacological Research. PMID 27317945 DOI: 10.1016/j.phrs.2016.05.035  0.36
2016 Yang Z, Li J, Xiong F, Huang J, Chen C, Liu P, Huang H. Berberine attenuates high glucose-induced fibrosis by activating the G protein-coupled bile acid receptor TGR5 and repressing the S1P2/MAPK signaling pathway in glomerular mesangial cells. Experimental Cell Research. PMID 27292312 DOI: 10.1016/j.yexcr.2016.06.005  0.36
2016 Wang Q, Li M, Zhang X, Huang H, Huang J, Ke J, Ding H, Xiao J, Shan X, Liu Q, Bao B, Yang L. Upregulation of CDK7 in gastric cancer cell promotes tumor cell proliferation and predicts poor prognosis. Experimental and Molecular Pathology. PMID 27155449 DOI: 10.1016/j.yexmp.2016.05.001  0.36
2016 Chen C, Huang K, Hao J, Huang J, Yang Z, Xiong F, Liu P, Huang H. Polydatin attenuates AGEs-induced upregulation of fibronectin and ICAM-1 in rat glomerular mesangial cells and db/db diabetic mice kidneys by inhibiting the activation of the SphK1-S1P signaling pathway. Molecular and Cellular Endocrinology. PMID 26948947 DOI: 10.1016/j.mce.2016.03.003  0.36
2016 Wang Y, Ye J, Li J, Chen C, Huang J, Liu P, Huang H. Polydatin ameliorates lipid and glucose metabolism in type 2 diabetes mellitus by downregulating proprotein convertase subtilisin/kexin type 9 (PCSK9). Cardiovascular Diabetology. 15: 19. PMID 26833058 DOI: 10.1186/s12933-015-0325-x  0.36
2016 Zhu X, Zhang Y, Huang H, Zhang H, Hou L, Zhang Z. Functionalized graphene oxide-based thermosensitive hydrogel for near-infrared chemo-photothermal therapy on tumor. Journal of Biomaterials Applications. PMID 26759390 DOI: 10.1177/0885328215619583  0.36
2016 Liu J, Liu X, Liu Y, Deng S, Huang H, Chen Q, Liu W, Huang Z. Association of EVI5 rs11808092, CD58 rs2300747, and CIITA rs3087456 polymorphisms with multiple sclerosis risk: A meta-analysis Meta Gene. 9: 97-103. DOI: 10.1016/j.mgene.2016.04.005  0.36
2016 Huang H, Chen F, Chen Z, Jiang M. Synthesis and Z-scan measurements of third-order optical nonlinearity of azothiazole- and azobenzothiazole-containing side-chain polymers Polymer Bulletin. 73: 1545-1552. DOI: 10.1007/s00289-015-1561-7  0.36
2015 Zhu X, Zhang H, Huang H, Zhang Y, Hou L, Zhang Z. Functionalized graphene oxide-based thermosensitive hydrogel for magnetic hyperthermia therapy on tumors. Nanotechnology. 26: 365103. PMID 26291977 DOI: 10.1088/0957-4484/26/36/365103  0.36
2015 Zhu X, Huang H, Zhang Y, Xie Y, Hou L, Zhang H, Zhang Z. Investigation on Single-walled Carbon Nanotubes-Liposomes Conjugate to Treatment Tumor with Dual-mechanism. Current Pharmaceutical Biotechnology. PMID 26212561  0.36
2015 Huang K, Chen C, Hao J, Huang J, Wang S, Liu P, Huang H. Polydatin promotes Nrf2-ARE anti-oxidative pathway through activating Sirt1 to resist AGEs-induced upregulation of fibronetin and transforming growth factor-β1 in rat glomerular messangial cells. Molecular and Cellular Endocrinology. 399: 178-89. PMID 25192797 DOI: 10.1016/j.mce.2014.08.014  0.36
2014 Hao J, Chen C, Huang K, Huang J, Li J, Liu P, Huang H. Polydatin improves glucose and lipid metabolism in experimental diabetes through activating the Akt signaling pathway. European Journal of Pharmacology. 745: 152-65. PMID 25310908 DOI: 10.1016/j.ejphar.2014.09.047  0.36
2014 Deng Y, Lan T, Huang J, Huang H. Sphingosine Kinase-1/sphingosine 1-phosphate pathway in diabetic nephropathy. Chinese Medical Journal. 127: 3004-10. PMID 25131242  0.36
2014 Xie X, Chen C, Huang K, Wang S, Hao J, Huang J, Huang H. RhoA/rho kinase signaling reduces connexin43 expression in high glucose-treated glomerular mesangial cells with zonula occludens-1 involvement. Experimental Cell Research. 327: 276-86. PMID 25064462 DOI: 10.1016/j.yexcr.2014.07.019  0.36
2014 Zhu X, Xie Y, Zhang Y, Huang H, Huang S, Hou L, Zhang H, Li Z, Shi J, Zhang Z. Thermo-sensitive liposomes loaded with doxorubicin and lysine modified single-walled carbon nanotubes as tumor-targeting drug delivery system. Journal of Biomaterials Applications. 29: 769-79. PMID 25033825 DOI: 10.1177/0885328214543211  0.36
2014 Zhu X, Huang S, Huang H, Zhang Y, Xie Y, Hou L, Zhang H, Shi J, Zhang Z. In vitro and in vivo anti-cancer effects of targeting and photothermal sensitive solid lipid nanoparticles. Journal of Drug Targeting. 22: 822-8. PMID 24964053 DOI: 10.3109/1061186X.2014.931405  0.36
2014 Lan T, Wu T, Chen C, Chen X, Hao J, Huang J, Wang L, Huang H. Berberine attenuates high glucose-induced proliferation and extracellular matrix accumulation in mesangial cells: involvement of suppression of cell cycle progression and NF-κB/AP-1 pathways. Molecular and Cellular Endocrinology. 384: 109-16. PMID 24508662 DOI: 10.1016/j.mce.2014.01.022  0.36
2014 Huang K, Huang J, Chen C, Hao J, Wang S, Huang J, Liu P, Huang H. AP-1 regulates sphingosine kinase 1 expression in a positive feedback manner in glomerular mesangial cells exposed to high glucose. Cellular Signalling. 26: 629-38. PMID 24342046 DOI: 10.1016/j.cellsig.2013.12.002  0.36
2013 Xie X, Chang X, Chen L, Huang K, Huang J, Wang S, Shen X, Liu P, Huang H. Berberine ameliorates experimental diabetes-induced renal inflammation and fibronectin by inhibiting the activation of RhoA/ROCK signaling. Molecular and Cellular Endocrinology. 381: 56-65. PMID 23896433 DOI: 10.1016/j.mce.2013.07.019  0.36
2013 Huang K, Huang J, Xie X, Wang S, Chen C, Shen X, Liu P, Huang H. Sirt1 resists advanced glycation end products-induced expressions of fibronectin and TGF-β1 by activating the Nrf2/ARE pathway in glomerular mesangial cells. Free Radical Biology & Medicine. 65: 528-40. PMID 23891678 DOI: 10.1016/j.freeradbiomed.2013.07.029  0.36
2013 Xie X, Lan T, Chang X, Huang K, Huang J, Wang S, Chen C, Shen X, Liu P, Huang H. Connexin43 mediates NF-κB signalling activation induced by high glucose in GMCs: involvement of c-Src. Cell Communication and Signaling : Ccs. 11: 38. PMID 23718910 DOI: 10.1186/1478-811X-11-38  0.36
2013 Xie X, Peng J, Chang X, Huang K, Huang J, Wang S, Shen X, Liu P, Huang H. Activation of RhoA/ROCK regulates NF-κB signaling pathway in experimental diabetic nephropathy. Molecular and Cellular Endocrinology. 369: 86-97. PMID 23376009 DOI: 10.1016/j.mce.2013.01.007  0.36
2013 Huang J, Huang K, Lan T, Xie X, Shen X, Liu P, Huang H. Curcumin ameliorates diabetic nephropathy by inhibiting the activation of the SphK1-S1P signaling pathway. Molecular and Cellular Endocrinology. 365: 231-40. PMID 23127801 DOI: 10.1016/j.mce.2012.10.024  0.36
2012 Lan T, Liu W, Xie X, Huang K, Peng J, Huang J, Shen X, Liu P, Yang H, Huang H. Berberine suppresses high glucose-induced TGF-β1 and fibronectin synthesis in mesangial cells through inhibition of sphingosine kinase 1/AP-1 pathway. European Journal of Pharmacology. 697: 165-72. PMID 23085271 DOI: 10.1016/j.ejphar.2012.10.003  0.36
2012 Huang K, Liu W, Lan T, Xie X, Peng J, Huang J, Wang S, Shen X, Liu P, Huang H. Berberine reduces fibronectin expression by suppressing the S1P-S1P2 receptor pathway in experimental diabetic nephropathy models. Plos One. 7: e43874. PMID 22937115 DOI: 10.1371/journal.pone.0043874  0.36
2012 Xie X, Peng J, Huang K, Huang J, Shen X, Liu P, Huang H. Polydatin ameliorates experimental diabetes-induced fibronectin through inhibiting the activation of NF-κB signaling pathway in rat glomerular mesangial cells. Molecular and Cellular Endocrinology. 362: 183-93. PMID 22732364 DOI: 10.1016/j.mce.2012.06.008  0.36
2012 Liu W, Lan T, Xie X, Huang K, Peng J, Huang J, Shen X, Liu P, Huang H. S1P2 receptor mediates sphingosine-1-phosphate-induced fibronectin expression via MAPK signaling pathway in mesangial cells under high glucose condition. Experimental Cell Research. 318: 936-43. PMID 22406263 DOI: 10.1016/j.yexcr.2012.02.020  0.36
2012 Le K, Li R, Xu S, Wu X, Huang H, Bao Y, Cai Y, Lan T, Moss J, Li C, Zou J, Shen X, Liu P. PPARα activation inhibits endothelin-1-induced cardiomyocyte hypertrophy by prevention of NFATc4 binding to GATA-4. Archives of Biochemistry and Biophysics. 518: 71-8. PMID 22198280 DOI: 10.1016/j.abb.2011.11.024  0.36
2011 Lan T, Liu W, Xie X, Xu S, Huang K, Peng J, Shen X, Liu P, Wang L, Xia P, Huang H. Sphingosine kinase-1 pathway mediates high glucose-induced fibronectin expression in glomerular mesangial cells. Molecular Endocrinology (Baltimore, Md.). 25: 2094-105. PMID 21998146 DOI: 10.1210/me.2011-0095  0.36
2011 Xu S, Little PJ, Lan T, Huang Y, Le K, Wu X, Shen X, Huang H, Cai Y, Tang F, Wang H, Liu P. Tanshinone II-A attenuates and stabilizes atherosclerotic plaques in apolipoprotein-E knockout mice fed a high cholesterol diet. Archives of Biochemistry and Biophysics. 515: 72-9. PMID 21889487 DOI: 10.1016/j.abb.2011.08.006  0.36
2011 Xie X, Li W, Lan T, Liu W, Peng J, Huang K, Huang J, Shen X, Liu P, Huang H. Berberine ameliorates hyperglycemia in alloxan-induced diabetic C57BL/6 mice through activation of Akt signaling pathway. Endocrine Journal. 58: 761-8. PMID 21705841 DOI: JST.JSTAGE/endocrj/K11E-024  0.36
2011 Lan T, Bi H, Liu W, Xie X, Xu S, Huang H. Simultaneous determination of sphingosine and sphingosine 1-phosphate in biological samples by liquid chromatography-tandem mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 879: 520-6. PMID 21292568 DOI: 10.1016/j.jchromb.2011.01.015  0.36
2011 Jiang Q, Liu P, Wu X, Liu W, Shen X, Lan T, Xu S, Peng J, Xie X, Huang H. Berberine attenuates lipopolysaccharide-induced extracelluar matrix accumulation and inflammation in rat mesangial cells: involvement of NF-κB signaling pathway. Molecular and Cellular Endocrinology. 331: 34-40. PMID 20674665 DOI: 10.1016/j.mce.2010.07.023  0.36
2010 Ma C, Huang H, Zhao C. An aptamer-based and pyrene-labeled fluorescent biosensor for homogeneous detection of potassium ions. Analytical Sciences : the International Journal of the Japan Society For Analytical Chemistry. 26: 1261-4. PMID 21157094 DOI: JST.JSTAGE/analsci/26.1261  0.32
2010 Xu S, Huang Y, Xie Y, Lan T, Le K, Chen J, Chen S, Gao S, Xu X, Shen X, Huang H, Liu P. Evaluation of foam cell formation in cultured macrophages: an improved method with Oil Red O staining and DiI-oxLDL uptake. Cytotechnology. 62: 473-81. PMID 21076992 DOI: 10.1007/s10616-010-9290-0  0.36
2010 Lan T, Shen X, Liu P, Liu W, Xu S, Xie X, Jiang Q, Li W, Huang H. Berberine ameliorates renal injury in diabetic C57BL/6 mice: Involvement of suppression of SphK-S1P signaling pathway. Archives of Biochemistry and Biophysics. 502: 112-20. PMID 20646989 DOI: 10.1016/j.abb.2010.07.012  0.36
2010 Liu W, Zhang X, Liu P, Shen X, Lan T, Li W, Jiang Q, Xie X, Huang H. Effects of berberine on matrix accumulation and NF-kappa B signal pathway in alloxan-induced diabetic mice with renal injury. European Journal of Pharmacology. 638: 150-5. PMID 20447389 DOI: 10.1016/j.ejphar.2010.04.033  0.36
2010 Lan T, Bi H, Xu S, Le K, Xie Z, Liu Y, Huang H. Determination of sphingosine kinase activity in biological samples by liquid chromatography-tandem mass spectrometry. Biomedical Chromatography : Bmc. 24: 1075-83. PMID 20352614 DOI: 10.1002/bmc.1407  0.36
2009 Xu S, Fu J, Chen J, Xiao P, Lan T, Le K, Cheng F, He L, Shen X, Huang H, Liu P. Development of an optimized protocol for primary culture of smooth muscle cells from rat thoracic aortas. Cytotechnology. 61: 65-72. PMID 19898948 DOI: 10.1007/s10616-009-9236-6  0.36
2009 Li X, Liu W, Wang Q, Liu P, Deng Y, Lan T, Zhang X, Qiu B, Ning H, Huang H. Emodin suppresses cell proliferation and fibronectin expression via p38MAPK pathway in rat mesangial cells cultured under high glucose. Molecular and Cellular Endocrinology. 307: 157-62. PMID 19524136 DOI: 10.1016/j.mce.2009.03.006  0.36
2009 Liu W, Tang F, Deng Y, Li X, Lan T, Zhang X, Huang H, Liu P. Berberine reduces fibronectin and collagen accumulation in rat glomerular mesangial cells cultured under high glucose condition. Molecular and Cellular Biochemistry. 325: 99-105. PMID 19142714 DOI: 10.1007/s11010-008-0024-y  0.36
2008 Liu W, Liu P, Tao S, Deng Y, Li X, Lan T, Zhang X, Guo F, Huang W, Chen F, Huang H, Zhou SF. Berberine inhibits aldose reductase and oxidative stress in rat mesangial cells cultured under high glucose. Archives of Biochemistry and Biophysics. 475: 128-34. PMID 18471986 DOI: 10.1016/j.abb.2008.04.022  0.36
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