Year |
Citation |
Score |
2023 |
Zhou Q, Yu L, Cook JR, Qiang L, Sun L. Deciphering the decline of metabolic elasticity in aging and obesity. Cell Metabolism. PMID 37625407 DOI: 10.1016/j.cmet.2023.08.001 |
0.303 |
|
2023 |
He Y, Zhang R, Yu L, Zahr T, Li X, Kim TW, Qiang L. PPARγ Acetylation in Adipocytes Exacerbates BAT Whitening and Worsens Age-Associated Metabolic Dysfunction. Cells. 12. PMID 37408258 DOI: 10.3390/cells12101424 |
0.312 |
|
2022 |
Aaron N, Zahr T, He Y, Yu L, Mayfield B, Pajvani UB, Qiang L. Acetylation of PPARγ in macrophages promotes visceral fat degeneration in obesity. Life Metabolism. 1: 258-269. PMID 37213714 DOI: 10.1093/lifemeta/loac032 |
0.359 |
|
2020 |
Richter LR, Wan Q, Wen D, Zhang Y, Yu J, Kang JK, McKinnon EL, Gu Z, Qiang L, Pajvani UB. Targeted Delivery of Notch Inhibitor Attenuates Obesity-Induced Glucose Intolerance and Liver Fibrosis. Acs Nano. PMID 32441510 DOI: 10.1021/Acsnano.0C01007 |
0.355 |
|
2020 |
Liu L, Fan L, Chan M, Kraakman MJ, Yang J, Fan Y, Aaron N, Wan Q, Carrillo-Sepulveda MA, Tall AR, Tabas I, Accili D, Qiang L. PPARγ Deacetylation Confers the Anti-Atherogenic Effect and Improves Endothelial Function in Diabetes Treatment. Diabetes. PMID 32409492 DOI: 10.2337/Db20-0217 |
0.359 |
|
2020 |
McCabe KM, Hsieh J, Thomas DG, Molusky MM, Tascau L, Feranil JB, Qiang L, Ferrante AW, Tall AR. Antisense oligonucleotide treatment produces a type I interferon response that protects against diet-induced obesity. Molecular Metabolism. 34: 146-156. PMID 32180554 DOI: 10.1016/J.Molmet.2020.01.010 |
0.42 |
|
2020 |
Liu Q, Yu J, Wang L, Tang Y, Zhou Q, Ji S, Wang Y, Santos L, Haeusler RA, Que J, Rajbhandari P, Lei X, Valenti L, Pajvani UB, Qin J, ... Qiang L, et al. Inhibition of PU.1 ameliorates metabolic dysfunction and non-alcoholic steatohepatitis. Journal of Hepatology. PMID 32135178 DOI: 10.1016/J.Jhep.2020.02.025 |
0.313 |
|
2019 |
Chan M, Lim YC, Yang J, Namwanje M, Liu L, Qiang L. Identification of a natural beige adipose depot in mice. The Journal of Biological Chemistry. PMID 30824545 DOI: 10.1074/Jbc.Ra118.006838 |
0.454 |
|
2019 |
Namwanje M, Liu L, Chan M, Aaron N, Kraakman MJ, Qiang L. The depot-specific and essential roles of CBP/p300 in regulating adipose plasticity. The Journal of Endocrinology. 240: 257-269. PMID 30530904 DOI: 10.1530/Joe-18-0361 |
0.392 |
|
2018 |
Chenxu G, Minxuan X, Yuting Q, Tingting G, Jing F, Jinxiao L, Sujun W, Yongjie M, Deshuai L, Qiang L, Linfeng H, Xuyuan N, Mingxing W, Ping H, Jun T. Loss of RIP3 initiates annihilation of high-fat diet initialized nonalcoholic hepatosteatosis: A mechanism involving Toll-like receptor 4 and oxidative stress. Free Radical Biology & Medicine. PMID 30599260 DOI: 10.1016/j.freeradbiomed.2018.12.034 |
0.303 |
|
2018 |
J Kraakman M, Liu Q, Postigo-Fernandez J, Ji R, Kon N, Larrea D, Namwanje M, Fan L, Chan M, Area-Gomez E, Fu W, J Creusot R, Qiang L. PPARγ deacetylation dissociates thiazolidinedione's metabolic benefits from its adverse effects. The Journal of Clinical Investigation. PMID 29589839 DOI: 10.1172/Jci98709 |
0.422 |
|
2018 |
Kim K, Goldberg IJ, Graham MJ, Sundaram M, Bertaggia E, Lee SX, Qiang L, Haeusler RA, Metzger D, Chambon P, Yao Z, Ginsberg HN, Pajvani UB. γ-Secretase Inhibition Lowers Plasma Triglyceride-Rich Lipoproteins by Stabilizing the LDL Receptor. Cell Metabolism. PMID 29576536 DOI: 10.1016/J.Cmet.2018.02.010 |
0.362 |
|
2018 |
Kon N, Wang D, Li T, Jiang L, Qiang L, Gu W. Inhibition of Mdmx (Mdm4)induces anti-obesity effects. Oncotarget. 9: 7282-7297. PMID 29484110 DOI: 10.18632/Oncotarget.23837 |
0.417 |
|
2017 |
Tamucci KA, Namwanje M, Fan L, Qiang L. The dark side of browning. Protein & Cell. PMID 28677104 DOI: 10.1007/S13238-017-0434-2 |
0.403 |
|
2016 |
Li D, Zhang F, Zhang X, Xue C, Namwanje M, Fan L, Reilly MP, Hu F, Qiang L. Distinct functions of PPARγ isoforms in regulating adipocyte plasticity. Biochemical and Biophysical Research Communications. PMID 27818196 DOI: 10.1016/J.Bbrc.2016.10.152 |
0.486 |
|
2016 |
Ferrannini G, Namwanje M, Fang B, Damle M, Li D, Liu Q, Lazar MA, Qiang L. Genetic backgrounds determine brown remodeling of white fat in rodents. Molecular Metabolism. 5: 948-58. PMID 27689007 DOI: 10.1016/J.Molmet.2016.08.013 |
0.361 |
|
2016 |
Kim K, Qiang L, Hayden MS, Sparling DP, Purcell NH, Pajvani UB. mTORC1-independent Raptor prevents hepatic steatosis by stabilizing PHLPP2. Nature Communications. 7: 10255. PMID 26743335 DOI: 10.1038/Ncomms10255 |
0.369 |
|
2015 |
Qiang L, Kon N, Zhao W, Jiang L, Knight CM, Welch C, Pajvani U, Gu W, Accili D. Hepatic SirT1-Dependent Gain of Function of Stearoyl-CoA Desaturase-1 Conveys Dysmetabolic and Tumor Progression Functions. Cell Reports. 11: 1797-808. PMID 26074075 DOI: 10.1016/J.Celrep.2015.05.025 |
0.369 |
|
2015 |
Mayoral R, Osborn O, McNelis J, Johnson AM, Oh da Y, Izquierdo CL, Chung H, Li P, Traves PG, Bandyopadhyay G, Pessentheiner AR, Ofrecio JM, Cook JR, Qiang L, Accili D, et al. Adipocyte SIRT1 knockout promotes PPARγ activity, adipogenesis and insulin sensitivity in chronic-HFD and obesity. Molecular Metabolism. 4: 378-91. PMID 25973386 DOI: 10.1016/J.Molmet.2015.02.007 |
0.46 |
|
2012 |
Qiang L, Wang L, Kon N, Zhao W, Lee S, Zhang Y, Rosenbaum M, Zhao Y, Gu W, Farmer SR, Accili D. Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Pparγ. Cell. 150: 620-32. PMID 22863012 DOI: 10.1016/J.Cell.2012.06.027 |
0.684 |
|
2012 |
Pino E, Wang H, McDonald ME, Qiang L, Farmer SR. Roles for peroxisome proliferator-activated receptor γ (PPARγ) and PPARγ coactivators 1α and 1β in regulating response of white and brown adipocytes to hypoxia. The Journal of Biological Chemistry. 287: 18351-8. PMID 22493496 DOI: 10.1074/Jbc.M112.350918 |
0.671 |
|
2012 |
Qiang L, Tsuchiya K, Kim-Muller JY, Lin HV, Welch C, Accili D. Increased atherosclerosis and endothelial dysfunction in mice bearing constitutively deacetylated alleles of Foxo1 gene. The Journal of Biological Chemistry. 287: 13944-51. PMID 22389493 DOI: 10.1074/Jbc.M111.332767 |
0.38 |
|
2011 |
Qiang L, Lin HV, Kim-Muller JY, Welch CL, Gu W, Accili D. Proatherogenic abnormalities of lipid metabolism in SirT1 transgenic mice are mediated through Creb deacetylation. Cell Metabolism. 14: 758-67. PMID 22078933 DOI: 10.1016/J.Cmet.2011.10.007 |
0.434 |
|
2011 |
Banks AS, Kim-Muller JY, Mastracci TL, Kofler NM, Qiang L, Haeusler RA, Jurczak MJ, Laznik D, Heinrich G, Samuel VT, Shulman GI, Papaioannou VE, Accili D. Dissociation of the glucose and lipid regulatory functions of FoxO1 by targeted knockin of acetylation-defective alleles in mice. Cell Metabolism. 14: 587-97. PMID 22055502 DOI: 10.1016/J.Cmet.2011.09.012 |
0.394 |
|
2011 |
Chakrabarti P, English T, Karki S, Qiang L, Tao R, Kim J, Luo Z, Farmer SR, Kandror KV. SIRT1 controls lipolysis in adipocytes via FOXO1-mediated expression of ATGL. Journal of Lipid Research. 52: 1693-701. PMID 21743036 DOI: 10.1194/Jlr.M014647 |
0.657 |
|
2010 |
Qiang L, Banks AS, Accili D. Uncoupling of acetylation from phosphorylation regulates FoxO1 function independent of its subcellular localization. The Journal of Biological Chemistry. 285: 27396-401. PMID 20519497 DOI: 10.1074/Jbc.M110.140228 |
0.34 |
|
2009 |
Vernochet C, Peres SB, Davis KE, McDonald ME, Qiang L, Wang H, Scherer PE, Farmer SR. C/EBPalpha and the corepressors CtBP1 and CtBP2 regulate repression of select visceral white adipose genes during induction of the brown phenotype in white adipocytes by peroxisome proliferator-activated receptor gamma agonists. Molecular and Cellular Biology. 29: 4714-28. PMID 19564408 DOI: 10.1128/Mcb.01899-08 |
0.753 |
|
2008 |
Wang H, Qiang L, Farmer SR. Identification of a domain within peroxisome proliferator-activated receptor gamma regulating expression of a group of genes containing fibroblast growth factor 21 that are selectively repressed by SIRT1 in adipocytes. Molecular and Cellular Biology. 28: 188-200. PMID 17954559 DOI: 10.1128/Mcb.00992-07 |
0.681 |
|
2007 |
Qiang L, Wang H, Farmer SR. Adiponectin secretion is regulated by SIRT1 and the endoplasmic reticulum oxidoreductase Ero1-L alpha. Molecular and Cellular Biology. 27: 4698-707. PMID 17452443 DOI: 10.1128/Mcb.02279-06 |
0.646 |
|
2006 |
Zuo Y, Qiang L, Farmer SR. Activation of CCAAT/enhancer-binding protein (C/EBP) alpha expression by C/EBP beta during adipogenesis requires a peroxisome proliferator-activated receptor-gamma-associated repression of HDAC1 at the C/ebp alpha gene promoter. The Journal of Biological Chemistry. 281: 7960-7. PMID 16431920 DOI: 10.1074/Jbc.M510682200 |
0.708 |
|
2006 |
Qiang L, Farmer SR. C/EBPalpha-dependent induction of glutathione S-transferase zeta/maleylacetoacetate isomerase (GSTzeta/MAAI) expression during the differentiation of mouse fibroblasts into adipocytes. Biochemical and Biophysical Research Communications. 340: 845-51. PMID 16376852 DOI: 10.1016/J.Bbrc.2005.12.067 |
0.644 |
|
2004 |
Park BH, Qiang L, Farmer SR. Phosphorylation of C/EBPbeta at a consensus extracellular signal-regulated kinase/glycogen synthase kinase 3 site is required for the induction of adiponectin gene expression during the differentiation of mouse fibroblasts into adipocytes. Molecular and Cellular Biology. 24: 8671-80. PMID 15367685 DOI: 10.1128/Mcb.24.19.8671-8680.2004 |
0.655 |
|
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