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Natalia A. Trayanova - Publications

Affiliations: 
Biomedical Engineering Johns Hopkins University, Baltimore, MD 
Area:
Biomedical Engineering
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288 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Trayanova NA, Lyon A, Shade J, Heijman J. Computational modeling of cardiac electrophysiology and arrhythmogenesis. Physiological Reviews. PMID 38153307 DOI: 10.1152/physrev.00017.2023  0.342
2023 Sung E, Kyranakis S, Daimee UA, Engels M, Prakosa A, Zhou S, Nazarian S, Zimmerman SL, Chrispin J, Trayanova NA. Evaluation of a deep Learning-enabled automated computational heart modeling workflow for personalized assessment of ventricular arrhythmias. The Journal of Physiology. PMID 37060278 DOI: 10.1113/JP284125  0.313
2022 Sung E, Prakosa A, Zhou S, Berger RD, Chrispin J, Nazarian S, Trayanova NA. Fat infiltration in the infarcted heart as a paradigm for ventricular arrhythmias. Nature Cardiovascular Research. 1: 933-945. PMID 36589896 DOI: 10.1038/s44161-022-00133-6  0.324
2022 Dawkins JF, Ehdaie A, Rogers R, Soetkamp D, Valle J, Holm K, Sanchez L, Tremmel I, Nawaz A, Shehata M, Wang X, Prakosa A, Yu J, Van Eyk JE, Trayanova N, et al. Biological substrate modification suppresses ventricular arrhythmias in a porcine model of chronic ischaemic cardiomyopathy. European Heart Journal. PMID 35262692 DOI: 10.1093/eurheartj/ehac042  0.316
2022 Salvador M, Regazzoni F, Pagani S, Dede' L, Trayanova N, Quarteroni A. The role of mechano-electric feedbacks and hemodynamic coupling in scar-related ventricular tachycardia. Computers in Biology and Medicine. 142: 105203. PMID 35033878 DOI: 10.1016/j.compbiomed.2021.105203  0.326
2021 Sung E, Etoz S, Zhang Y, Trayanova NA. Whole-heart ventricular arrhythmia modeling moving forward: Mechanistic insights and translational applications. Biophysics Reviews. 2. PMID 36281224 DOI: 10.1063/5.0058050  0.353
2021 Sung E, Prakosa A, Trayanova NA. Analyzing the Role of Repolarization Gradients in Post-infarct Ventricular Tachycardia Dynamics Using Patient-Specific Computational Heart Models. Frontiers in Physiology. 12: 740389. PMID 34658925 DOI: 10.3389/fphys.2021.740389  0.323
2021 Ochs AR, Karathanos TV, Trayanova NA, Boyle PM. Optogenetic Stimulation Using Anion Channelrhodopsin (GtACR1) Facilitates Termination of Reentrant Arrhythmias With Low Light Energy Requirements: A Computational Study. Frontiers in Physiology. 12: 718622. PMID 34526912 DOI: 10.3389/fphys.2021.718622  0.329
2021 Salvador M, Fedele M, Africa PC, Sung E, Dede' L, Prakosa A, Chrispin J, Trayanova N, Quarteroni A. Electromechanical modeling of human ventricles with ischemic cardiomyopathy: numerical simulations in sinus rhythm and under arrhythmia. Computers in Biology and Medicine. 136: 104674. PMID 34340126 DOI: 10.1016/j.compbiomed.2021.104674  0.317
2020 Aronis KN, Trayanova NA. Endocardial-Epicardial Dissociation in Persistent Atrial Fibrillation: Driver or Bystander Activation Pattern? Circulation. Arrhythmia and Electrophysiology. 13: e009110. PMID 32809877 DOI: 10.1161/Circep.120.009110  0.303
2020 Feeny AK, Chung MK, Madabhushi A, Attia ZI, Cikes M, Firouznia M, Friedman PA, Kalscheur MM, Kapa S, Narayan SM, Noseworthy PA, Passman RS, Perez MV, Peters NS, Piccini JP, ... ... Trayanova NA, et al. Artificial Intelligence and Machine Learning in Arrhythmias and Cardiac Electrophysiology. Circulation. Arrhythmia and Electrophysiology. PMID 32628863 DOI: 10.1161/Circep.119.007952  0.31
2020 Shade JK, Ali RL, Basile D, Popescu D, Akhtar T, Marine JE, Spragg DD, Calkins H, Trayanova NA. Pre-Procedure Application of Machine Learning and Mechanistic Simulations Predicts Likelihood of Paroxysmal Atrial Fibrillation Recurrence Following Pulmonary Vein Isolation. Circulation. Arrhythmia and Electrophysiology. PMID 32536204 DOI: 10.1161/Circep.119.008213  0.322
2020 Roney CH, Bendikas R, Pashakhanloo F, Corrado C, Vigmond EJ, McVeigh ER, Trayanova NA, Niederer SA. Constructing a Human Atrial Fibre Atlas. Annals of Biomedical Engineering. PMID 32458222 DOI: 10.1007/S10439-020-02525-W  0.312
2020 Habibi M, Chrispin J, Spragg DD, Zimmerman SL, Tandri H, Nazarian S, Halperin H, Trayanova N, Calkins H. Utility of Cardiac MRI in Atrial Fibrillation Management. Cardiac Electrophysiology Clinics. 12: 131-139. PMID 32451098 DOI: 10.1016/J.Ccep.2020.02.006  0.364
2020 Aronis KN, Ali RL, Prakosa A, Ashikaga H, Berger RD, Hakim JB, Liang J, Tandri H, Teng F, Chrispin J, Trayanova NA. Accurate Conduction Velocity Maps and their Association with Scar Distribution on Magnetic Resonance Imaging in Patients with Post-Infarction Ventricular Tachycardias. Circulation. Arrhythmia and Electrophysiology. PMID 32191131 DOI: 10.1161/Circep.119.007792  0.352
2020 Okada DR, Miller J, Chrispin J, Prakosa A, Trayanova N, Jones S, Maggioni M, Wu KC. Substrate Spatial Complexity Analysis for the Prediction of Ventricular Arrhythmias in Patients with Ischemic Cardiomyopathy. Circulation. Arrhythmia and Electrophysiology. PMID 32188287 DOI: 10.1161/Circep.119.007975  0.351
2020 Dhamala J, Bajracharya P, Arevalo HJ, Sapp JL, Horácek BM, Wu KC, Trayanova NA, Wang L. Embedding high-dimensional Bayesian optimization via generative modeling: Parameter personalization of cardiac electrophysiological models. Medical Image Analysis. 62: 101670. PMID 32171168 DOI: 10.1016/J.Media.2020.101670  0.323
2020 Trayanova NA, Doshi AN, Prakosa A. How personalized heart modeling can help treatment of lethal arrhythmias: A focus on ventricular tachycardia ablation strategies in post-infarction patients. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. e1477. PMID 31917524 DOI: 10.1002/Wsbm.1477  0.406
2020 Liang JA, Yu JK, Trayanova NA. Targeted Remuscularization can Reduce Ventricular Tachycardia (VT) Burden in a Computational Human Heart Model of Post-Myocardial Infarction (MI) Biophysical Journal. 118: 493a. DOI: 10.1016/J.Bpj.2019.11.2728  0.409
2019 Izu LT, Kohl P, Boyden PA, Miura M, Banyasz T, Chiamvimonvat N, Trayanova N, Bers DM, Chen-Izu Y. Mechano-electric and mechano-chemo-transduction in cardiomyocytes. The Journal of Physiology. PMID 31789427 DOI: 10.1113/Jp276494  0.303
2019 Ustunkaya T, Desjardins B, Wedan R, Chahal CAA, Zimmerman SL, Saju N, Zahid S, Sharma A, Han Y, Trayanova N, Marchlinski FE, Calkins H, Tandri H, Nazarian S. Epicardial Conduction Speed, Electrogram Abnormality, and Computed Tomography Attenuation Associations in Arrhythmogenic Right Ventricular Cardiomyopathy. Jacc. Clinical Electrophysiology. 5: 1158-1167. PMID 31648740 DOI: 10.1016/J.Jacep.2019.06.017  0.333
2019 Shade JK, Cartoski MJ, Nikolov P, Prakosa A, Doshi A, Binka E, Olivieri L, Boyle PM, Spevak PJ, Trayanova NA. Ventricular Arrhythmia Risk Prediction in Repaired Tetralogy of Fallot using Personalized Computational Cardiac Models. Heart Rhythm. PMID 31589989 DOI: 10.1016/J.Hrthm.2019.10.002  0.373
2019 Grondin J, Wang D, Grubb CS, Trayanova N, Konofagou EE. 4D cardiac electromechanical activation imaging. Computers in Biology and Medicine. 113: 103382. PMID 31476587 DOI: 10.1016/J.Compbiomed.2019.103382  0.419
2019 Aronis KN, Ali RL, Liang JA, Zhou S, Trayanova NA. Understanding AF Mechanisms Through Computational Modelling and Simulations. Arrhythmia & Electrophysiology Review. 8: 210-219. PMID 31463059 DOI: 10.15420/Aer.2019.28.2  0.398
2019 Deng D, Prakosa A, Shade J, Nikolov P, Trayanova NA. Characterizing Conduction Channels in Postinfarction Patients Using a Personalized Virtual Heart. Biophysical Journal. PMID 31447108 DOI: 10.1016/J.Bpj.2019.07.024  0.382
2019 Boyle PM, Zghaib T, Zahid S, Ali RL, Deng D, Franceschi WH, Hakim JB, Murphy MJ, Prakosa A, Zimmerman SL, Ashikaga H, Marine JE, Kolandaivelu A, Nazarian S, Spragg DD, ... ... Trayanova NA, et al. Computationally guided personalized targeted ablation of persistent atrial fibrillation. Nature Biomedical Engineering. PMID 31427780 DOI: 10.1038/S41551-019-0437-9  0.363
2019 Yu JK, Franceschi W, Huang Q, Pashakhanloo F, Boyle PM, Trayanova NA. A comprehensive, multiscale framework for evaluation of arrhythmias arising from cell therapy in the whole post-myocardial infarcted heart. Scientific Reports. 9: 9238. PMID 31239508 DOI: 10.1038/S41598-019-45684-0  0.423
2019 Deng D, Prakosa A, Shade J, Nikolov P, Trayanova NA. Sensitivity of Ablation Targets Prediction to Electrophysiological Parameter Variability in Image-Based Computational Models of Ventricular Tachycardia in Post-infarction Patients. Frontiers in Physiology. 10: 628. PMID 31178758 DOI: 10.3389/Fphys.2019.00628  0.443
2019 Roney CH, Pashaei A, Meo M, Dubois R, Boyle PM, Trayanova NA, Cochet H, Niederer SA, Vigmond EJ. Universal atrial coordinates applied to visualisation, registration and construction of patient specific meshes. Medical Image Analysis. 55: 65-75. PMID 31026761 DOI: 10.1016/J.Media.2019.04.004  0.331
2019 Ali RL, Hakim JB, Boyle PM, Zahid S, Sivasambu B, Marine JE, Calkins H, Trayanova NA, Spragg DD. Arrhythmogenic Propensity of the Fibrotic Substrate after AF Ablation: A Longitudinal Study using MRI-Based Atrial Models. Cardiovascular Research. PMID 30977811 DOI: 10.1093/Cvr/Cvz083  0.342
2019 Ustunkaya T, Desjardins B, Liu B, Zahid S, Park J, Saju N, Trayanova N, Zimmerman SL, Marchlinski FE, Nazarian S. Association of regional myocardial conduction velocity with the distribution of hypoattenuation on contrast-enhanced perfusion computed tomography in patients with postinfarct ventricular tachycardia. Heart Rhythm. 16: 588-594. PMID 30935494 DOI: 10.1016/J.Hrthm.2018.10.029  0.376
2019 Cartoski MJ, Nikolov PP, Prakosa A, Boyle PM, Spevak PJ, Trayanova NA. Computational Identification of Ventricular Arrhythmia Risk in Pediatric Myocarditis. Pediatric Cardiology. PMID 30840104 DOI: 10.1007/S00246-019-02082-7  0.4
2019 Aronis KN, Ali R, Trayanova NA. The role of personalized atrial modeling in understanding atrial fibrillation mechanisms and improving treatment. International Journal of Cardiology. PMID 30755334 DOI: 10.1016/J.Ijcard.2019.01.096  0.383
2019 Boyle PM, Franceschi WH, Constantin M, Hawks C, Desplantez T, Trayanova NA, Vigmond EJ. New insights on the cardiac safety factor: Unraveling the relationship between conduction velocity and robustness of propagation. Journal of Molecular and Cellular Cardiology. PMID 30677394 DOI: 10.1016/J.Yjmcc.2019.01.010  0.39
2019 Smith N, Trayanova N. Computational models of heart disease. Drug Discovery Today. Disease Models. 14: 1-2. PMID 26843884 DOI: 10.1016/J.Ddmod.2014.12.002  0.387
2019 Trayanova N, Skouibine K, Aguel F. The role of cardiac tissue structure in defibrillation. Chaos (Woodbury, N.Y.). 8: 221-233. PMID 12779723 DOI: 10.1063/1.166299  0.415
2019 Trayanova N, Eason J. Shock-induced arrhythmogenesis in the myocardium. Chaos (Woodbury, N.Y.). 12: 962-972. PMID 12779620 DOI: 10.1063/1.1483955  0.386
2018 Prakosa A, Arevalo HJ, Deng D, Boyle PM, Nikolov PP, Ashikaga H, Blauer JJ, Ghafoori E, Park CJ, Blake RC, Han FT, MacLeod RS, Halperin HR, Callans DJ, Ranjan R, ... ... Trayanova NA, et al. Personalized virtual-heart technology for guiding the ablation of infarct-related ventricular tachycardia. Nature Biomedical Engineering. 2: 732-740. PMID 30847259 DOI: 10.1038/S41551-018-0282-2  0.419
2018 Loucks AD, O'Hara T, Trayanova NA. Degradation of T-Tubular Microdomains and Altered cAMP Compartmentation Lead to Emergence of Arrhythmogenic Triggers in Heart Failure Myocytes: An Study. Frontiers in Physiology. 9: 1737. PMID 30564142 DOI: 10.3389/Fphys.2018.01737  0.394
2018 Hakim JB, Murphy MJ, Trayanova NA, Boyle PM. Arrhythmia dynamics in computational models of the atria following virtual ablation of re-entrant drivers. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. 20: iii45-iii54. PMID 30476053 DOI: 10.1093/Europace/Euy234  0.344
2018 Ukwatta E, Nikolov P, Zabihollahy F, Trayanova NA, Wright GA. Virtual electrophysiological study as a tool for evaluating efficacy of MRI techniques in predicting adverse arrhythmic events in ischemic patients. Physics in Medicine and Biology. 63: 225008. PMID 30412472 DOI: 10.1088/1361-6560/Aae8B2  0.385
2018 Niederer SA, Lumens J, Trayanova NA. Computational models in cardiology. Nature Reviews. Cardiology. PMID 30361497 DOI: 10.1038/S41569-018-0104-Y  0.3
2018 Deng D, Nikolov P, Arevalo HJ, Trayanova NA. Optimal contrast-enhanced MRI image thresholding for accurate prediction of ventricular tachycardia using ex-vivo high resolution models. Computers in Biology and Medicine. PMID 30301573 DOI: 10.1016/J.Compbiomed.2018.09.031  0.432
2018 Boyle PM, Hakim JB, Zahid S, Franceschi WH, Murphy MJ, Prakosa A, Aronis KN, Zghaib T, Balouch M, Ipek EG, Chrispin J, Berger RD, Ashikaga H, Marine JE, Calkins H, ... ... Trayanova NA, et al. The Fibrotic Substrate in Persistent Atrial Fibrillation Patients: Comparison Between Predictions From Computational Modeling and Measurements From Focal Impulse and Rotor Mapping. Frontiers in Physiology. 9: 1151. PMID 30210356 DOI: 10.3389/Fphys.2018.01151  0.365
2018 Zile MA, Trayanova NA. Increased Thin Filament Activation Enhances Alternans in Human Chronic Atrial Fibrillation. American Journal of Physiology. Heart and Circulatory Physiology. PMID 30141984 DOI: 10.1152/Ajpheart.00658.2017  0.392
2018 Pashakhanloo F, Herzka DA, Halperin H, McVeigh ER, Trayanova NA. Role of 3-Dimensional Architecture of Scar and Surviving Tissue in Ventricular Tachycardia: Insights From High-Resolution Ex Vivo Porcine Models. Circulation. Arrhythmia and Electrophysiology. 11: e006131. PMID 29880529 DOI: 10.1161/Circep.117.006131  0.389
2018 Misra S, Zahid S, Prakosa A, Saju N, Tandri H, Berger RD, Marine JE, Calkins H, Zipunnikov V, Trayanova N, Zimmerman SL, Nazarian S. The Field of View of Mapping Catheters Quantified by Electrogram Associations with Radius of Myocardial Attenuation on Contrast-Enhanced Cardiac Computed Tomography. Heart Rhythm. PMID 29870783 DOI: 10.1016/J.Hrthm.2018.05.031  0.361
2018 Dhamala J, Arevalo HJ, Sapp J, Horácek BM, Wu KC, Trayanova NA, Wang L. Quantifying the uncertainty in model parameters using Gaussian process-based Markov chain Monte Carlo in cardiac electrophysiology. Medical Image Analysis. 48: 43-57. PMID 29843078 DOI: 10.1016/J.Media.2018.05.007  0.303
2018 Boyle PM, Karathanos TV, Trayanova NA. Cardiac Optogenetics: 2018. Jacc. Clinical Electrophysiology. 4: 155-167. PMID 29749932 DOI: 10.1016/J.Jacep.2017.12.006  0.429
2018 Boyle PM, Hakim JB, Zahid S, Franceschi WH, Murphy MJ, Vigmond EJ, Dubois R, Haïssaguerre M, Hocini M, Jaïs P, Trayanova NA, Cochet H. Comparing Reentrant Drivers Predicted by Image-Based Computational Modeling and Mapped by Electrocardiographic Imaging in Persistent Atrial Fibrillation. Frontiers in Physiology. 9: 414. PMID 29725307 DOI: 10.3389/Fphys.2018.00414  0.359
2018 Trayanova NA, Boyle PM, Nikolov PP. Personalized Imaging and Modeling Strategies for Arrhythmia Prevention and Therapy. Current Opinion in Biomedical Engineering. 5: 21-28. PMID 29546250 DOI: 10.1016/J.Cobme.2017.11.007  0.441
2018 Yuniarti AR, Setianto F, Marcellinus A, Hwang HJ, Choi SW, Trayanova N, Lim KM. EFFECT OF KCNQ1 G229D MUTATION ON CARDIAC PUMPING EFFICACY AND REENTRANT DYNAMICS IN VENTRICLES: COMPUTATIONAL STUDY. International Journal For Numerical Methods in Biomedical Engineering. PMID 29488358 DOI: 10.1002/Cnm.2970  0.366
2018 Cochet H, Dubois R, Yamashita S, Al Jefairi N, Berte B, Sellal JM, Hooks D, Frontera A, Amraoui S, Zemoura A, Denis A, Derval N, Sacher F, Corneloup O, Latrabe V, ... ... Trayanova NA, et al. Relationship Between Fibrosis Detected on Late Gadolinium-Enhanced Cardiac Magnetic Resonance and Re-Entrant Activity Assessed With Electrocardiographic Imaging in Human Persistent Atrial Fibrillation. Jacc. Clinical Electrophysiology. 4: 17-29. PMID 29479568 DOI: 10.1016/J.Jacep.2017.07.019  0.36
2017 Boyle PM, Murphy MJ, Karathanos TV, Zahid S, Blake RC, Trayanova NA. Termination of reentrant atrial tachycardia via optogenetic stimulation with optimized spatial targeting: insights from computational models. The Journal of Physiology. PMID 29193078 DOI: 10.1113/Jp275264  0.342
2017 Kang C, Badiceanu A, Brennan JA, Gloschat C, Qiao Y, Trayanova NA, Efimov IR. β-adrenergic stimulation augments transmural dispersion of repolarization via modulation of delayed rectifier currents IKs and IKr in the human ventricle. Scientific Reports. 7: 15922. PMID 29162896 DOI: 10.1038/S41598-017-16218-3  0.346
2017 Heikhmakhtiar AK, Ryu AJ, Shim EB, Song KS, Trayanova NA, Lim KM. Influence of LVAD function on mechanical unloading and electromechanical delay: a simulation study. Medical & Biological Engineering & Computing. PMID 29098548 DOI: 10.1007/S11517-017-1730-Y  0.366
2017 Kim YS, Yuniarti AR, Song KS, Trayanova NA, Shim EB, Lim KM. Computational analysis of the effect of mitral and aortic regurgitation on the function of ventricular assist devices using 3D cardiac electromechanical model. Medical & Biological Engineering & Computing. PMID 29080191 DOI: 10.1007/S11517-017-1727-6  0.432
2017 Kim CH, Song KS, Trayanova NA, Lim KM. Computational prediction of the effects of the intra-aortic balloon pump on heart failure with valvular regurgitation using a 3D cardiac electromechanical model. Medical & Biological Engineering & Computing. PMID 29058110 DOI: 10.1007/S11517-017-1731-X  0.393
2017 Deng D, Murphy MJ, Hakim JB, Franceschi WH, Zahid S, Pashakhanloo F, Trayanova NA, Boyle PM. Sensitivity of reentrant driver localization to electrophysiological parameter variability in image-based computational models of persistent atrial fibrillation sustained by a fibrotic substrate. Chaos (Woodbury, N.Y.). 27: 093932. PMID 28964164 DOI: 10.1063/1.5003340  0.401
2017 Cerrone M, Montnach J, Lin X, Zhao YT, Zhang M, Agullo-Pascual E, Leo-Macias A, Alvarado FJ, Dolgalev I, Karathanos TV, Malkani K, Van Opbergen CJM, van Bavel JJA, Yang HQ, Vasquez C, ... ... Trayanova NA, et al. Plakophilin-2 is required for transcription of genes that control calcium cycling and cardiac rhythm. Nature Communications. 8: 106. PMID 28740174 DOI: 10.1038/S41467-017-00127-0  0.311
2017 Trayanova NA, Pashakhanloo F, Wu KC, Halperin HR. Imaging-Based Simulations for Predicting Sudden Death and Guiding Ventricular Tachycardia Ablation. Circulation. Arrhythmia and Electrophysiology. 10. PMID 28696219 DOI: 10.1161/Circep.117.004743  0.403
2017 Zile MA, Trayanova NA. Myofilament protein dynamics modulate EAD formation in human hypertrophic cardiomyopathy. Progress in Biophysics and Molecular Biology. PMID 28648627 DOI: 10.1016/J.Pbiomolbio.2017.06.015  0.364
2017 Dhamala J, Arevalo H, Sapp J, Horacek M, Wu K, Trayanova N, Wang L. Spatially-Adaptive Multi-Scale Optimization for Local Parameter Estimation in Cardiac Electrophysiology. Ieee Transactions On Medical Imaging. PMID 28459685 DOI: 10.1109/Tmi.2017.2697820  0.335
2017 Boyle PM, Zahid S, Trayanova NA. Using personalized computer models to custom-tailor ablation procedures for atrial fibrillation patients: are we there yet? Expert Review of Cardiovascular Therapy. PMID 28395557 DOI: 10.1080/14779072.2017.1317593  0.316
2017 Pashakhanloo F, Herzka DA, Mori S, Zviman M, Halperin H, Gai N, Bluemke DA, Trayanova NA, McVeigh ER. Submillimeter diffusion tensor imaging and late gadolinium enhancement cardiovascular magnetic resonance of chronic myocardial infarction. Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society For Cardiovascular Magnetic Resonance. 19: 9. PMID 28122618 DOI: 10.1186/S12968-016-0317-3  0.363
2017 Aboelkassem Y, Trayanova N. Cardiac Electromechanical Coupling Model of Myocardial Contractile Function under Ischemic Conditions Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.578  0.391
2017 Aboelkassem Y, Trayanova N. Tropomyosin Fluctuations Over a Multi-Well Energy Landscape: A Brownian Ratchet Model of Cardiac Muscle Contraction Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.1411  0.339
2016 Roney CH, Bayer JD, Zahid S, Meo M, Boyle PM, Trayanova NA, Haïssaguerre M, Dubois R, Cochet H, Vigmond EJ. Modelling methodology of atrial fibrosis affects rotor dynamics and electrograms. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. 18: iv146-iv155. PMID 28011842 DOI: 10.1093/Europace/Euw365  0.706
2016 Boyle PM, Zahid S, Trayanova NA. Towards personalized computational modelling of the fibrotic substrate for atrial arrhythmia. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. 18: iv136-iv145. PMID 28011841 DOI: 10.1093/Europace/Euw358  0.386
2016 Deng D, Arevalo HJ, Prakosa A, Callans DJ, Trayanova NA. A feasibility study of arrhythmia risk prediction in patients with myocardial infarction and preserved ejection fraction. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. 18: iv60-iv66. PMID 28011832 DOI: 10.1093/Europace/Euw351  0.388
2016 Chang KC, Trayanova NA. Mechanisms of arrhythmogenesis related to calcium-driven alternans in a model of human atrial fibrillation. Scientific Reports. 6: 36395. PMID 27812021 DOI: 10.1038/Srep36395  0.362
2016 Priest JR, Gawad C, Kahlig KM, Yu JK, O'Hara T, Boyle PM, Rajamani S, Clark MJ, Garcia ST, Ceresnak S, Harris J, Boyle S, Dewey FE, Malloy-Walton L, Dunn K, ... ... Trayanova NA, et al. Early somatic mosaicism is a rare cause of long-QT syndrome. Proceedings of the National Academy of Sciences of the United States of America. PMID 27681629 DOI: 10.1073/Pnas.1607187113  0.341
2016 Bruegmann T, Boyle PM, Vogt CC, Karathanos TV, Arevalo HJ, Fleischmann BK, Trayanova NA, Sasse P. Optogenetic defibrillation terminates ventricular arrhythmia in mouse hearts and human simulations. The Journal of Clinical Investigation. PMID 27617859 DOI: 10.1172/Jci88950  0.446
2016 Sanchez-Alonso JL, Bhargava A, O'Hara T, Glukhov AV, Schobesberger S, Bhogal NK, Sikkel MB, Mansfield C, Korchev YE, Lyon AR, Punjabi PP, Nikolaev VO, Trayanova NA, Gorelik J. Microdomain-Specific Modulation of L-type Calcium Channels Leads to Triggered Ventricular Arrhythmia in Heart Failure. Circulation Research. PMID 27572487 DOI: 10.1161/Circresaha.116.308698  0.393
2016 Zghaib T, Ipek EG, Zahid S, Balouch MA, Misra S, Ashikaga H, Berger RD, Marine JE, Spragg DD, Zimmerman SL, Zipunnikov V, Trayanova N, Calkins H, Nazarian S. Association of left atrial epicardial adipose tissue with electrogram bipolar voltage and fractionation: Electrophysiologic substrates for atrial fibrillation. Heart Rhythm : the Official Journal of the Heart Rhythm Society. PMID 27546816 DOI: 10.1016/J.Hrthm.2016.08.030  0.337
2016 Arevalo HJ, Boyle PM, Trayanova NA. Computational rabbit models to investigate the initiation, perpetuation, and termination of ventricular arrhythmia. Progress in Biophysics and Molecular Biology. PMID 27334789 DOI: 10.1016/J.Pbiomolbio.2016.06.004  0.463
2016 Bayer JD, Lalani GG, Vigmond EJ, Narayan SM, Trayanova NA. Mechanisms Linking Electrical Alternans and Clinical Ventricular Arrhythmia in Human Heart Failure. Heart Rhythm : the Official Journal of the Heart Rhythm Society. PMID 27215536 DOI: 10.1016/J.Hrthm.2016.05.017  0.718
2016 Arevalo HJ, Vadakkumpadan F, Guallar E, Jebb A, Malamas P, Wu KC, Trayanova NA. Arrhythmia risk stratification of patients after myocardial infarction using personalized heart models. Nature Communications. 7: 11437. PMID 27164184 DOI: 10.1038/Ncomms11437  0.412
2016 Zhang Y, Barocas VH, Berceli SA, Clancy CE, Eckmann DM, Garbey M, Kassab GS, Lochner DR, McCulloch AD, Tran-Son-Tay R, Trayanova NA. Multi-scale Modeling of the Cardiovascular System: Disease Development, Progression, and Clinical Intervention. Annals of Biomedical Engineering. PMID 27138523 DOI: 10.1007/S10439-016-1628-0  0.334
2016 Zahid S, Whyte KN, Schwarz EL, Blake RC, Boyle PM, Chrispin J, Prakosa A, Ipek EG, Pashakhanloo F, Halperin HA, Calkins H, Berger RD, Nazarian S, Trayanova NA. Feasibility of Using Patient-Specific Models and the "Minimum Cut" Algorithm to Predict Optimal Ablation Targets for Left Atrial Flutter. Heart Rhythm : the Official Journal of the Heart Rhythm Society. PMID 27108938 DOI: 10.1016/J.Hrthm.2016.04.009  0.335
2016 Pashakhanloo F, Herzka DA, Ashikaga H, Mori S, Gai N, Bluemke DA, Trayanova NA, McVeigh ER. Myofiber Architecture of the Human Atria as Revealed by Submillimeter Diffusion Tensor Imaging. Circulation. Arrhythmia and Electrophysiology. 9. PMID 27071829 DOI: 10.1161/Circep.116.004133  0.311
2016 Zahid S, Cochet H, Boyle PM, Schwarz EL, Whyte KN, Vigmond EJ, Dubois R, Hocini M, Haïssaguerre M, Jaïs P, Trayanova NA. Patient-derived models link reentrant driver localization in atrial fibrillation to fibrosis spatial pattern. Cardiovascular Research. PMID 27056895 DOI: 10.1093/Cvr/Cvw073  0.345
2016 Karathanos TV, Bayer JD, Wang D, Boyle PM, Trayanova NA. Opsin spectral sensitivity determines the effectiveness of optogenetic termination of ventricular fibrillation in the human heart: A simulation study. The Journal of Physiology. PMID 26941055 DOI: 10.1113/Jp271739  0.702
2016 Fukumoto K, Habibi M, Ipek EG, Zahid S, Khurram IM, Zimmerman SL, Zipunnikov V, Spragg D, Ashikaga H, Trayanova N, Tomaselli GF, Rickard J, Marine JE, Berger RD, Calkins H, et al. Association of Left Atrial Local Conduction Velocity With Late Gadolinium Enhancement on Cardiac Magnetic Resonance in Patients With Atrial Fibrillation. Circulation. Arrhythmia and Electrophysiology. 9: e002897. PMID 26917814 DOI: 10.1161/Circep.115.002897  0.366
2016 Haissaguerre M, Shah AJ, Cochet H, Hocini M, Dubois R, Efimov I, Vigmond E, Bernus O, Trayanova N. Intermittent drivers anchoring to structural heterogeneities as a major pathophysiologic mechanism of human persistent atrial fibrillation. The Journal of Physiology. PMID 26890861 DOI: 10.1113/Jp270617  0.392
2016 Molitoris JM, Paliwal S, Sekar RB, Blake R, Park J, Trayanova NA, Tung L, Levchenko A. Precisely parameterized experimental and computational models of tissue organization. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 26822672 DOI: 10.1039/C5Ib00270B  0.336
2016 Boyle PM, Murphy M, Karathanos TV, Wang D, Zahid S, Whyte KN, Schwarz EL, Entcheva E, Trayanova NA. Pulse Duration Determines Efficacy of Arrhythmia Termination via Targeted Optogenetic Stimulation Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.3127  0.374
2016 Yu JK, Boyle PM, O'Hara T, Priest JR, Ashley E, Trayanova NA. Somatic Mosaicism of Novel SCN5A Mutation in Purkinje System (PS) may Underlie 2:1 Block in an Infant with Long QT Syndrome (LQTS) Biophysical Journal. 110: 527a. DOI: 10.1016/J.Bpj.2015.11.2820  0.345
2015 Land S, Gurev V, Arens S, Augustin CM, Baron L, Blake R, Bradley C, Castro S, Crozier A, Favino M, Fastl TE, Fritz T, Gao H, Gizzi A, Griffith BE, ... ... Trayanova N, et al. Verification of cardiac mechanics software: benchmark problems and solutions for testing active and passive material behaviour. Proceedings. Mathematical, Physical, and Engineering Sciences / the Royal Society. 471: 20150641. PMID 26807042 DOI: 10.1098/Rspa.2015.0641  0.382
2015 Ukwatta E, Arevalo H, Li K, Yuan J, Qiu W, Malamas P, Wu KC, Trayanova NA, Vadakkumpadan F. Myocardial Infarct Segmentation from Magnetic Resonance Images for Personalized Modeling of Cardiac Electrophysiology. Ieee Transactions On Medical Imaging. PMID 26731693 DOI: 10.1109/Tmi.2015.2512711  0.4
2015 Zile MA, Trayanova NA. Rate-dependent force, intracellular calcium, and action potential voltage alternans are modulated by sarcomere length and heart failure induced-remodeling of thin filament regulation in human heart failure: A myocyte modeling study. Progress in Biophysics and Molecular Biology. PMID 26724571 DOI: 10.1016/J.Pbiomolbio.2015.12.012  0.386
2015 Ukwatta E, Rajchl M, White J, Pashakhanloo F, Herzka DA, McVeigh E, Lardo AC, Trayanova N, Vadakkumpadan F. Image-based Reconstruction of 3D Myocardial Infarct Geometry for Patient Specific Applications. Proceedings of Spie--the International Society For Optical Engineering. 9413. PMID 26633913 DOI: 10.1117/12.2082113  0.344
2015 Trayanova NA, Chang KC. How computer simulations of the human heart can improve anti-arrhythmia therapy. The Journal of Physiology. PMID 26621489 DOI: 10.1113/Jp270532  0.434
2015 Ambrosi CM, Boyle PM, Chen K, Trayanova NA, Entcheva E. Optogenetics-enabled assessment of viral gene and cell therapy for restoration of cardiac excitability. Scientific Reports. 5: 17350. PMID 26621212 DOI: 10.1038/Srep17350  0.374
2015 Chrispin J, Ipek EG, Zahid S, Prakosa A, Habibi M, Spragg D, Marine JE, Ashikaga H, Rickard J, Trayanova NA, Zimmerman SL, Zipunnikov V, Berger RD, Calkins H, Nazarian S. Lack of Regional Association between Atrial Late Gadolinium Enhancement on Cardiac Magnetic Resonance and Atrial Fibrillation Rotors. Heart Rhythm : the Official Journal of the Heart Rhythm Society. PMID 26569460 DOI: 10.1016/J.Hrthm.2015.11.011  0.366
2015 Deng D, Arevalo H, Pashakhanloo F, Prakosa A, Ashikaga H, McVeigh E, Halperin H, Trayanova N. Accuracy of prediction of infarct-related arrhythmic circuits from image-based models reconstructed from low and high resolution MRI. Frontiers in Physiology. 6: 282. PMID 26528188 DOI: 10.3389/Fphys.2015.00282  0.404
2015 Choi YJ, Constantino J, Vedula V, Trayanova N, Mittal R. A New MRI-Based Model of Heart Function with Coupled Hemodynamics and Application to Normal and Diseased Canine Left Ventricles. Frontiers in Bioengineering and Biotechnology. 3: 140. PMID 26442254 DOI: 10.3389/Fbioe.2015.00140  0.451
2015 Ukwatta E, Arevalo H, Rajchl M, White J, Pashakhanloo F, Prakosa A, Herzka DA, McVeigh E, Lardo AC, Trayanova NA, Vadakkumpadan F. Image-based reconstruction of three-dimensional myocardial infarct geometry for patient-specific modeling of cardiac electrophysiology. Medical Physics. 42: 4579-90. PMID 26233186 DOI: 10.1118/1.4926428  0.387
2015 Boyle PM, Karathanos TV, Entcheva E, Trayanova NA. Computational modeling of cardiac optogenetics: Methodology overview & review of findings from simulations. Computers in Biology and Medicine. 65: 200-8. PMID 26002074 DOI: 10.1016/J.Compbiomed.2015.04.036  0.418
2015 Khrapko K, Trayanova N, Nattel S. Modeling the aging heart: from local respiratory defects to global rhythm disturbances. Cell Metabolism. 21: 662-3. PMID 25955202 DOI: 10.1016/J.Cmet.2015.04.024  0.371
2015 McDowell KS, Zahid S, Vadakkumpadan F, Blauer J, MacLeod RS, Trayanova NA. Virtual electrophysiological study of atrial fibrillation in fibrotic remodeling. Plos One. 10: e0117110. PMID 25692857 DOI: 10.1371/Journal.Pone.0117110  0.38
2015 Lim KM, Hong SB, Lee BK, Shim EB, Trayanova N. Computational analysis of the effect of valvular regurgitation on ventricular mechanics using a 3D electromechanics model. The Journal of Physiological Sciences : Jps. 65: 159-64. PMID 25644379 DOI: 10.1007/S12576-014-0353-4  0.373
2015 Boyle PM, Karathanos TV, Trayanova NA. "Beauty is a light in the heart": the transformative potential of optogenetics for clinical applications in cardiovascular medicine. Trends in Cardiovascular Medicine. 25: 73-81. PMID 25453984 DOI: 10.1016/J.Tcm.2014.10.004  0.388
2015 Boyle PM, Karathanos TV, Entcheva E, Trayanova NA. Corrigendum to: Computational modeling of cardiac optogenetics: Methodology overview & review of findings from simulations [Comput. Biol. Med. 65C (2015) 200-208] DOI: 10.1016/j.compbiomed.2015.04.036 Computers in Biology and Medicine. 67: 184. DOI: 10.1016/J.Compbiomed.2015.10.006  0.333
2015 Karathanos TV, Boyle PM, Bayer JD, Wang D, Trayanova NA. Opsin Spectral Sensitivity Determines the Effectiveness of Optogenetics-Based Defibrillation Biophysical Journal. 108: 148a. DOI: 10.1016/J.Bpj.2014.11.817  0.688
2015 Zile M, Trayanova N. Large Amplitude Rate-Dependent Mechanical Alternans may Precede Arrhythmogenesis in Human Heart Failure and are Linked to Electrical Alternans via Abnormal Calcium Handling Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.2757  0.359
2015 Ramchandran V, O’Hara T, Markandeya YS, Balijepalli RC, Kamp TJ, Trayanova NA. Ionic Mechanisms that Underlie Ventricular Action Potential Prolongation following Loss of Caveolin-3 in Adult Transgenic Mice Biophysical Journal. 108: 195a. DOI: 10.1016/J.Bpj.2014.11.1076  0.356
2015 Trayanova NA, Boyle PM. Cardiac arrhythmias: Mechanistic knowledge and innovation from computer models Modeling, Simulation and Applications. 14: 1-27. DOI: 10.1007/978-3-319-05230-4_1  0.349
2014 Chang KC, Bayer JD, Trayanova NA. Disrupted calcium release as a mechanism for atrial alternans associated with human atrial fibrillation. Plos Computational Biology. 10: e1004011. PMID 25501557 DOI: 10.1371/Journal.Pcbi.1004011  0.729
2014 Trayanova NA, Boyle PM, Arevalo HJ, Zahid S. Exploring susceptibility to atrial and ventricular arrhythmias resulting from remodeling of the passive electrical properties in the heart: a simulation approach. Frontiers in Physiology. 5: 435. PMID 25429272 DOI: 10.3389/Fphys.2014.00435  0.479
2014 Karathanos TV, Boyle PM, Trayanova NA. Optogenetics-enabled dynamic modulation of action potential duration in atrial tissue: feasibility of a novel therapeutic approach. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. 16: iv69-iv76. PMID 25362173 DOI: 10.1093/Europace/Euu250  0.371
2014 Prakosa A, Malamas P, Zhang S, Pashakhanloo F, Arevalo H, Herzka DA, Lardo A, Halperin H, McVeigh E, Trayanova N, Vadakkumpadan F. Methodology for image-based reconstruction of ventricular geometry for patient-specific modeling of cardiac electrophysiology. Progress in Biophysics and Molecular Biology. 115: 226-34. PMID 25148771 DOI: 10.1016/J.Pbiomolbio.2014.08.009  0.344
2014 Vadakkumpadan F, Trayanova N, Wu KC. Image-based left ventricular shape analysis for sudden cardiac death risk stratification. Heart Rhythm. 11: 1693-700. PMID 24854217 DOI: 10.1016/J.Hrthm.2014.05.018  0.38
2014 Trayanova NA, Rantner LJ. New insights into defibrillation of the heart from realistic simulation studies. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. 16: 705-13. PMID 24798960 DOI: 10.1093/Europace/Eut330  0.815
2014 Trayanova NA. Mathematical approaches to understanding and imaging atrial fibrillation: significance for mechanisms and management. Circulation Research. 114: 1516-31. PMID 24763468 DOI: 10.1161/Circresaha.114.302240  0.385
2014 Hu Y, Gurev V, Constantino J, Trayanova N. Optimizing cardiac resynchronization therapy to minimize ATP consumption heterogeneity throughout the left ventricle: a simulation analysis using a canine heart failure model. Heart Rhythm. 11: 1063-9. PMID 24657430 DOI: 10.1016/J.Hrthm.2014.03.021  0.393
2014 Boyle PM, Park CJ, Arevalo HJ, Vigmond EJ, Trayanova NA. Sodium current reduction unmasks a structure-dependent substrate for arrhythmogenesis in the normal ventricles. Plos One. 9: e86947. PMID 24489810 DOI: 10.1371/Journal.Pone.0086947  0.398
2014 Zhou L, Solhjoo S, Millare B, Plank G, Abraham MR, Cortassa S, Trayanova N, O'Rourke B. Effects of regional mitochondrial depolarization on electrical propagation: implications for arrhythmogenesis. Circulation. Arrhythmia and Electrophysiology. 7: 143-51. PMID 24382411 DOI: 10.1161/Circep.113.000600  0.301
2014 Trayanova NA, Boyle PM. Advances in modeling ventricular arrhythmias: from mechanisms to the clinic. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 6: 209-24. PMID 24375958 DOI: 10.1002/Wsbm.1256  0.463
2014 Trayanova NA. Virtual 3D heart models to aid pacemaker implantation in children. Future Cardiology. 10: 5-8. PMID 24344653 DOI: 10.2217/Fca.13.94  0.441
2014 Boyle PM, Entcheva E, Trayanova NA. See the light: can optogenetics restore healthy heartbeats? And, if it can, is it really worth the effort? Expert Review of Cardiovascular Therapy. 12: 17-20. PMID 24308809 DOI: 10.1586/14779072.2014.864951  0.394
2014 Trayanova NA. Your personal virtual heart Ieee Spectrum. 51: 34-59. DOI: 10.1109/Mspec.2014.6934929  0.424
2014 Trayanova NA. Models of arrhythmogenesis in myocardial infarction Ifmbe Proceedings. 41: 1859-1863. DOI: 10.1007/978-3-319-00846-2_458  0.334
2013 Boyle PM, Williams JC, Ambrosi CM, Entcheva E, Trayanova NA. A comprehensive multiscale framework for simulating optogenetics in the heart. Nature Communications. 4: 2370. PMID 23982300 DOI: 10.1038/Ncomms3370  0.409
2013 Constantino J, Hu Y, Lardo AC, Trayanova NA. Mechanistic insight into prolonged electromechanical delay in dyssynchronous heart failure: a computational study. American Journal of Physiology. Heart and Circulatory Physiology. 305: H1265-73. PMID 23934857 DOI: 10.1152/Ajpheart.00426.2013  0.418
2013 Hu Y, Gurev V, Constantino J, Trayanova N. Efficient preloading of the ventricles by a properly timed atrial contraction underlies stroke work improvement in the acute response to cardiac resynchronization therapy. Heart Rhythm. 10: 1800-6. PMID 23928177 DOI: 10.1016/J.Hrthm.2013.08.003  0.367
2013 Arevalo H, Plank G, Helm P, Halperin H, Trayanova N. Tachycardia in post-infarction hearts: insights from 3D image-based ventricular models. Plos One. 8: e68872. PMID 23844245 DOI: 10.1371/Journal.Pone.0068872  0.449
2013 Rantner LJ, Vadakkumpadan F, Spevak PJ, Crosson JE, Trayanova NA. Placement of implantable cardioverter-defibrillators in paediatric and congenital heart defect patients: a pipeline for model generation and simulation prediction of optimal configurations. The Journal of Physiology. 591: 4321-34. PMID 23798492 DOI: 10.1113/Jphysiol.2013.255109  0.804
2013 McDowell KS, Vadakkumpadan F, Blake R, Blauer J, Plank G, Macleod RS, Trayanova NA. Mechanistic inquiry into the role of tissue remodeling in fibrotic lesions in human atrial fibrillation. Biophysical Journal. 104: 2764-73. PMID 23790385 DOI: 10.1016/J.Bpj.2013.05.025  0.337
2013 Rantner LJ, Tice BM, Trayanova NA. Terminating ventricular tachyarrhythmias using far-field low-voltage stimuli: mechanisms and delivery protocols. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 10: 1209-17. PMID 23628521 DOI: 10.1016/J.Hrthm.2013.04.027  0.77
2013 Ashikaga H, Arevalo H, Vadakkumpadan F, Blake RC, Bayer JD, Nazarian S, Muz Zviman M, Tandri H, Berger RD, Calkins H, Herzka DA, Trayanova NA, Halperin HR. Feasibility of image-based simulation to estimate ablation target in human ventricular arrhythmia. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 10: 1109-16. PMID 23608593 DOI: 10.1016/J.Hrthm.2013.04.015  0.682
2013 Hu Y, Gurev V, Constantino J, Bayer JD, Trayanova NA. Effects of mechano-electric feedback on scroll wave stability in human ventricular fibrillation. Plos One. 8: e60287. PMID 23573245 DOI: 10.1371/Journal.Pone.0060287  0.677
2013 Weinberg SH, Chang KC, Zhu R, Tandri H, Berger RD, Trayanova NA, Tung L. Defibrillation success with high frequency electric fields is related to degree and location of conduction block. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 10: 740-8. PMID 23354078 DOI: 10.1016/J.Hrthm.2013.01.016  0.362
2013 Vadakkumpadan F, Arevalo H, Trayanova NA. Patient-specific modeling of the heart: estimation of ventricular fiber orientations. Journal of Visualized Experiments : Jove. PMID 23329052 DOI: 10.3791/50125  0.388
2013 Ashihara T, Haraguchi R, Inada K, Nakazawa S, Ikeda T, Ozawa T, Ito M, Trayanova N, Horie M. Functional properties of complex fractionated atrial electrograms during atrial fibrillation can be explained by structural remodelling: a simulation study Journal of Electrocardiology. 46. DOI: 10.1016/J.Jelectrocard.2013.05.074  0.338
2012 Trayanova NA. Computational cardiology: the heart of the matter. Isrn Cardiology. 2012: 269680. PMID 23213566 DOI: 10.5402/2012/269680  0.423
2012 Gurev V, Tavakolian K, Constantino J, Kaminska B, Blaber AP, Trayanova NA. Mechanisms Underlying Isovolumic Contraction and Ejection Peaks in Seismocardiogram Morphology. Journal of Medical and Biological Engineering. 32: 103-110. PMID 23105942 DOI: 10.5405/Jmbe.847  0.428
2012 Trayanova NA, O'Hara T, Bayer JD, Boyle PM, McDowell KS, Constantino J, Arevalo HJ, Hu Y, Vadakkumpadan F. Computational cardiology: how computer simulations could be used to develop new therapies and advance existing ones. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. 14: v82-v89. PMID 23104919 DOI: 10.1093/Europace/Eus277  0.723
2012 Krummen DE, Bayer JD, Ho J, Ho G, Smetak MR, Clopton P, Trayanova NA, Narayan SM. Mechanisms of human atrial fibrillation initiation: clinical and computational studies of repolarization restitution and activation latency. Circulation. Arrhythmia and Electrophysiology. 5: 1149-59. PMID 23027797 DOI: 10.1161/Circep.111.969022  0.711
2012 McDowell KS, Vadakkumpadan F, Blake R, Blauer J, Plank G, MacLeod RS, Trayanova NA. Methodology for patient-specific modeling of atrial fibrosis as a substrate for atrial fibrillation. Journal of Electrocardiology. 45: 640-5. PMID 22999492 DOI: 10.1016/J.Jelectrocard.2012.08.005  0.426
2012 Constantino J, Hu Y, Trayanova NA. A computational approach to understanding the cardiac electromechanical activation sequence in the normal and failing heart, with translation to the clinical practice of CRT. Progress in Biophysics and Molecular Biology. 110: 372-9. PMID 22884712 DOI: 10.1016/J.Pbiomolbio.2012.07.009  0.456
2012 Bayer JD, Blake RC, Plank G, Trayanova NA. A novel rule-based algorithm for assigning myocardial fiber orientation to computational heart models. Annals of Biomedical Engineering. 40: 2243-54. PMID 22648575 DOI: 10.1007/S10439-012-0593-5  0.708
2012 Rantner LJ, Arevalo HJ, Constantino JL, Efimov IR, Plank G, Trayanova NA. Three-dimensional mechanisms of increased vulnerability to electric shocks in myocardial infarction: altered virtual electrode polarizations and conduction delay in the peri-infarct zone. The Journal of Physiology. 590: 4537-51. PMID 22586222 DOI: 10.1113/Jphysiol.2012.229088  0.816
2012 Trayanova N. In the Spotlight: Cardiovascular Engineering. Ieee Reviews in Biomedical Engineering. 1: 12-4. PMID 22274894 DOI: 10.1109/Rbme.2009.2034695  0.344
2012 Vadakkumpadan F, Arevalo H, Ceritoglu C, Miller M, Trayanova N. Image-based estimation of ventricular fiber orientations for personalized modeling of cardiac electrophysiology. Ieee Transactions On Medical Imaging. 31: 1051-60. PMID 22271833 DOI: 10.1109/Tmi.2012.2184799  0.375
2012 Ashihara T, Haraguchi R, Nakazawa K, Namba T, Ikeda T, Nakazawa Y, Ozawa T, Ito M, Horie M, Trayanova NA. The role of fibroblasts in complex fractionated electrograms during persistent/permanent atrial fibrillation: implications for electrogram-based catheter ablation. Circulation Research. 110: 275-84. PMID 22179057 DOI: 10.1161/Circresaha.111.255026  0.399
2012 Lim KM, Constantino J, Gurev V, Zhu R, Shim EB, Trayanova NA. Comparison of the effects of continuous and pulsatile left ventricular-assist devices on ventricular unloading using a cardiac electromechanics model. The Journal of Physiological Sciences : Jps. 62: 11-9. PMID 22076841 DOI: 10.1007/S12576-011-0180-9  0.407
2012 Chen X, Trayanova NA. A novel methodology for assessing the bounded-input bounded-output instability in QT interval dynamics: application to clinical ECG with ventricular tachycardia. Ieee Transactions On Bio-Medical Engineering. 59: 2111-7. PMID 21984490 DOI: 10.1109/Tbme.2011.2170837  0.302
2012 Yamazaki M, Honjo H, Ashihara T, Harada M, Sakuma I, Nakazawa K, Trayanova N, Horie M, Kalifa J, Jalife J, Kamiya K, Kodama I. Regional cooling facilitates termination of spiral-wave reentry through unpinning of rotors in rabbit hearts. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 9: 107-14. PMID 21839044 DOI: 10.1016/J.Hrthm.2011.08.013  0.359
2012 Trayanova NA. Modeling of Ventricular Arrhythmias Cardiac Mapping: Fourth Edition. 140-149. DOI: 10.1002/9781118481585.ch15  0.357
2011 Trayanova N, Constantino J, Ashihara T, Plank G. Modeling defibrillation of the heart: approaches and insights. Ieee Reviews in Biomedical Engineering. 4: 89-102. PMID 22273793 DOI: 10.1109/Rbme.2011.2173761  0.465
2011 Tandri H, Weinberg SH, Chang KC, Zhu R, Trayanova NA, Tung L, Berger RD. Reversible cardiac conduction block and defibrillation with high-frequency electric field. Science Translational Medicine. 3: 102ra96. PMID 21957174 DOI: 10.1126/Scitranslmed.3002445  0.46
2011 McDowell KS, Arevalo HJ, Maleckar MM, Trayanova NA. Susceptibility to arrhythmia in the infarcted heart depends on myofibroblast density. Biophysical Journal. 101: 1307-15. PMID 21943411 DOI: 10.1016/J.Bpj.2011.08.009  0.726
2011 Trayanova NA, Rice JJ. Cardiac electromechanical models: from cell to organ. Frontiers in Physiology. 2: 43. PMID 21886622 DOI: 10.3389/Fphys.2011.00043  0.377
2011 Moreno JD, Zhu ZI, Yang PC, Bankston JR, Jeng MT, Kang C, Wang L, Bayer JD, Christini DJ, Trayanova NA, Ripplinger CM, Kass RS, Clancy CE. A computational model to predict the effects of class I anti-arrhythmic drugs on ventricular rhythms. Science Translational Medicine. 3: 98ra83. PMID 21885405 DOI: 10.1126/Scitranslmed.3002588  0.723
2011 Chen X, Hu Y, Fetics BJ, Berger RD, Trayanova NA. Unstable QT interval dynamics precedes ventricular tachycardia onset in patients with acute myocardial infarction: a novel approach to detect instability in QT interval dynamics from clinical ECG. Circulation. Arrhythmia and Electrophysiology. 4: 858-66. PMID 21841208 DOI: 10.1161/Circep.110.961763  0.348
2011 Quinn TA, Granite S, Allessie MA, Antzelevitch C, Bollensdorff C, Bub G, Burton RA, Cerbai E, Chen PS, Delmar M, Difrancesco D, Earm YE, Efimov IR, Egger M, Entcheva E, ... ... Trayanova NA, et al. Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): standardised reporting for model reproducibility, interoperability, and data sharing. Progress in Biophysics and Molecular Biology. 107: 4-10. PMID 21745496 DOI: 10.1016/J.Pbiomolbio.2011.07.001  0.367
2011 Trayanova NA, Constantino J, Gurev V. Electromechanical models of the ventricles. American Journal of Physiology. Heart and Circulatory Physiology. 301: H279-86. PMID 21572017 DOI: 10.1152/Ajpheart.00324.2011  0.466
2011 Cetingül HE, Plank G, Trayanova NA, Vidal R. Estimation of local orientations in fibrous structures with applications to the Purkinje system. Ieee Transactions On Bio-Medical Engineering. 58: 1762-72. PMID 21335301 DOI: 10.1109/Tbme.2011.2116119  0.307
2011 Trayanova NA. Whole-heart modeling: applications to cardiac electrophysiology and electromechanics. Circulation Research. 108: 113-28. PMID 21212393 DOI: 10.1161/Circresaha.110.223610  0.445
2011 Provost J, Gurev V, Trayanova N, Konofagou EE. Mapping of cardiac electrical activation with electromechanical wave imaging: an in silico-in vivo reciprocity study. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 8: 752-9. PMID 21185403 DOI: 10.1016/J.Hrthm.2010.12.034  0.391
2011 Gurev V, Lee T, Constantino J, Arevalo H, Trayanova NA. Models of cardiac electromechanics based on individual hearts imaging data: image-based electromechanical models of the heart. Biomechanics and Modeling in Mechanobiology. 10: 295-306. PMID 20589408 DOI: 10.1007/S10237-010-0235-5  0.472
2011 Ashikaga H, Arevalo H, Vadakkumpadan F, Blake R, Berger R, Calkins H, Trayanova N, Halperin H. MR-Based, Patient-Specific Computational Simulation to Recapitulate Scar-Related Ventricular Tachycardia Journal of Arrhythmia. 27: YIAC_3. DOI: 10.4020/Jhrs.27.Yiac_3  0.36
2011 Ashihara T, Haraguchi R, Inada S, Nakazawa K, Ozawa T, Nakazawa Y, Ito M, Horie M, Trayanova N. Mechanisms of Complex Fractionated Electrogram-Targeted Ablation in a Model for Chronic Atrial Fibrillation Journal of Arrhythmia. 27: OP27_4. DOI: 10.4020/Jhrs.27.Op27_4  0.355
2011 Bayer J, Narayan S, Lalani G, Trayanova N. Spatially discordant alternans in action potential voltage underlie T-wave alternans in human heart failure Journal of Electrocardiology. 44: e14-e15. DOI: 10.1016/J.Jelectrocard.2010.12.043  0.688
2011 Tereshchenko LG, Kim R, Han L, Das D, Cheng K, Robinson E, Schulman S, Brinker J, Berger R, Trayanova N. Mechanical Alternans Strongly Correlates With T Wave Alternans and Predicts Death in Mild and Moderate, but Not End-Stage Heart Failure Patients Heart Rhythm. 8: 1825. DOI: 10.1016/J.Hrthm.2011.09.044  0.365
2011 Zhou L, Solhjoo S, Plank G, Abraham R, Cortassa S, Trayanova N, O'Rourke B. Regional Mitochondrial Depolarization Causes Spontaneous Ventricular Arrhythmia in Cardiac Tissue Biophysical Journal. 100: 435a-436a. DOI: 10.1016/J.Bpj.2010.12.2568  0.376
2011 Park CJ, Arevalo HJ, Trayanova NA. Arrhythmogenesis in Brugada Syndrome: Role of Ventricular Structure Biophysical Journal. 100: 435a. DOI: 10.1016/J.Bpj.2010.12.2567  0.431
2011 Bayer JD, Krummen DE, Narayan SM, Trayanova N. Beta-Adrenergic Stimulation Alters Both ion Channel Currents and Functional Refractory Period to Steepen Action Potential Duration Restitution in Persistent Atrial Fibrillation Biophysical Journal. 100: 434a-435a. DOI: 10.1016/J.Bpj.2010.12.2563  0.703
2010 Fishman GI, Chugh SS, Dimarco JP, Albert CM, Anderson ME, Bonow RO, Buxton AE, Chen PS, Estes M, Jouven X, Kwong R, Lathrop DA, Mascette AM, Nerbonne JM, O'Rourke B, ... ... Trayanova NA, et al. Sudden cardiac death prediction and prevention: report from a National Heart, Lung, and Blood Institute and Heart Rhythm Society Workshop. Circulation. 122: 2335-48. PMID 21147730 DOI: 10.1161/Circulationaha.110.976092  0.389
2010 Trayanova N. Atrial defibrillation voltage: falling to a new low. Heart Rhythm. 8: 109-10. PMID 21044899 DOI: 10.1016/J.Hrthm.2010.10.037  0.403
2010 Gurev V, Constantino J, Rice JJ, Trayanova NA. Distribution of electromechanical delay in the heart: Insights from a three-dimensional electromechanical model Biophysical Journal. 99: 745-754. PMID 20682251 DOI: 10.1016/J.Bpj.2010.05.028  0.374
2010 Trayanova NA, Constantino J, Gurev V. Models of stretch-activated ventricular arrhythmias. Journal of Electrocardiology. 43: 479-85. PMID 20638670 DOI: 10.1016/J.Jelectrocard.2010.05.014  0.408
2010 Vadakkumpadan F, Arevalo H, Prassl AJ, Chen J, Kickinger F, Kohl P, Plank G, Trayanova N. Image-based models of cardiac structure in health and disease. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 2: 489-506. PMID 20582162 DOI: 10.1002/Wsbm.76  0.422
2010 Bayer JD, Narayan SM, Lalani GG, Trayanova NA. Rate-dependent action potential alternans in human heart failure implicates abnormal intracellular calcium handling. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 7: 1093-101. PMID 20382266 DOI: 10.1016/J.Hrthm.2010.04.008  0.693
2010 Constantino J, Long Y, Ashihara T, Trayanova NA. Tunnel propagation following defibrillation with ICD shocks: hidden postshock activations in the left ventricular wall underlie isoelectric window. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 7: 953-61. PMID 20348028 DOI: 10.1016/J.Hrthm.2010.03.026  0.354
2010 Jie X, Trayanova NA. Mechanisms for initiation of reentry in acute regional ischemia phase 1B. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 7: 379-86. PMID 20097623 DOI: 10.1016/J.Hrthm.2009.11.014  0.572
2010 Jie X, Gurev V, Trayanova N. Mechanisms of mechanically induced spontaneous arrhythmias in acute regional ischemia Circulation Research. 106: 185-192. PMID 19893011 DOI: 10.1161/Circresaha.109.210864  0.608
2009 Trayanova NA, Tice BM. Integrative computational models of cardiac arrhythmias -- simulating the structurally realistic heart. Drug Discovery Today. Disease Models. 6: 85-91. PMID 20628585 DOI: 10.1016/J.Ddmod.2009.08.001  0.816
2009 Akhbardeh A, Tavakolian K, Gurev V, Lee T, New W, Kaminska B, Trayanova N. Comparative analysis of three different modalities for characterization of the seismocardiogram. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2009: 2899-903. PMID 19964786 DOI: 10.1109/IEMBS.2009.5334444  0.308
2009 Maleckar MM, Greenstein JL, Giles WR, Trayanova NA. Electrotonic coupling between human atrial myocytes and fibroblasts alters myocyte excitability and repolarization. Biophysical Journal. 97: 2179-90. PMID 19843450 DOI: 10.1016/J.Bpj.2009.07.054  0.7
2009 Maleckar MM, Greenstein JL, Giles WR, Trayanova NA. K+ current changes account for the rate dependence of the action potential in the human atrial myocyte. American Journal of Physiology. Heart and Circulatory Physiology. 297: H1398-410. PMID 19633207 DOI: 10.1152/Ajpheart.00411.2009  0.693
2009 Vigmond E, Vadakkumpadan F, Gurev V, Arevalo H, Deo M, Plank G, Trayanova N. Towards predictive modelling of the electrophysiology of the heart. Experimental Physiology. 94: 563-77. PMID 19270037 DOI: 10.1113/Expphysiol.2008.044073  0.457
2009 Prassl AJ, Kickinger F, Ahammer H, Grau V, Schneider JE, Hofer E, Vigmond EJ, Trayanova NA, Plank G. Automatically generated, anatomically accurate meshes for cardiac electrophysiology problems. Ieee Transactions On Bio-Medical Engineering. 56: 1318-30. PMID 19203877 DOI: 10.1109/Tbme.2009.2014243  0.392
2009 Vadakkumpadan F, Rantner LJ, Tice B, Boyle P, Prassl AJ, Vigmond E, Plank G, Trayanova N. Image-based models of cardiac structure with applications in arrhythmia and defibrillation studies. Journal of Electrocardiology. 42: 157.e1-10. PMID 19181330 DOI: 10.1016/J.Jelectrocard.2008.12.003  0.78
2009 Akhbardeh A, Vadakkumpadan F, Bayer JD, Trayanova NA. Locally homogenized and de-noised vector fields for cardiac fiber tracking in DT-MRI images Proceedings of Spie. 7261. DOI: 10.1117/12.811629  0.69
2009 Vadakkumpadan F, Arevalo H, Ceritoglu C, Miller M, Trayanova N. Image-Based Estimation of Myocardial Fiber Orientations for Patient-Specific Models of Cardiac Electrophysiology Heart Rhythm. 6: 1688. DOI: 10.1016/J.Hrthm.2009.09.038  0.373
2009 Constantino JL, Gurev V, Trayanova NA. Electromechanical Delay is Heterogeneous in the Failing Canine Ventricles Both during Left Bundle Branch Block and Following Biventricular Pacing Heart Rhythm. 6: 1687. DOI: 10.1016/J.Hrthm.2009.09.035  0.313
2009 Bayer JD, Narayan SM, Lalani GG, Trayanova NA. Cardiac Electrophysiology Society abstractBasic Science AbstractRate-Dependent Action Potential Alternans in Human Heart Failure Implicate Abnormalities in Intracellular Calcium Handling Heart Rhythm. 6. DOI: 10.1016/J.Hrthm.2009.09.030  0.708
2009 Zhou L, Trayanova N, Plank G, Aon M, Cortassa S, O'Rourke B. Effects Of Mitochondrial Depolarization On Cardiac Electrical Activity In An Integrated Multiscale Model Of The Myocardium Biophysical Journal. 96: 663a-664a. DOI: 10.1016/J.Bpj.2008.12.3508  0.398
2008 Maleckar MM, Greenstein JL, Trayanova NA, Giles WR. Mathematical simulations of ligand-gated and cell-type specific effects on the action potential of human atrium. Progress in Biophysics and Molecular Biology. 98: 161-70. PMID 19186188 DOI: 10.1016/J.Pbiomolbio.2009.01.010  0.71
2008 Narayan SM, Bayer JD, Lalani G, Trayanova NA. Action potential dynamics explain arrhythmic vulnerability in human heart failure: a clinical and modeling study implicating abnormal calcium handling. Journal of the American College of Cardiology. 52: 1782-92. PMID 19022157 DOI: 10.1016/J.Jacc.2008.08.037  0.713
2008 Rudy Y, Ackerman MJ, Bers DM, Clancy CE, Houser SR, London B, McCulloch AD, Przywara DA, Rasmusson RL, Solaro RJ, Trayanova NA, Van Wagoner DR, Varró A, Weiss JN, Lathrop DA. Systems approach to understanding electromechanical activity in the human heart: a national heart, lung, and blood institute workshop summary. Circulation. 118: 1202-11. PMID 18779456 DOI: 10.1161/Circulationaha.108.772715  0.397
2008 Maleckar MM, Woods MC, Sidorov VY, Holcomb MR, Mashburn DN, Wikswo JP, Trayanova NA. Polarity reversal lowers activation time during diastolic field stimulation of the rabbit ventricles: insights into mechanisms. American Journal of Physiology. Heart and Circulatory Physiology. 295: H1626-33. PMID 18708441 DOI: 10.1152/Ajpheart.00706.2008  0.704
2008 Plank G, Zhou L, Greenstein JL, Cortassa S, Winslow RL, O'Rourke B, Trayanova NA. From mitochondrial ion channels to arrhythmias in the heart: computational techniques to bridge the spatio-temporal scales. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 366: 3381-409. PMID 18603526 DOI: 10.1098/Rsta.2008.0112  0.419
2008 Jie X, Rodríguez B, de Groot JR, Coronel R, Trayanova N. Reentry in survived subepicardium coupled to depolarized and inexcitable midmyocardium: insights into arrhythmogenesis in ischemia phase 1B. Heart Rhythm. 5: 1036-44. PMID 18598961 DOI: 10.1016/J.Hrthm.2008.03.025  0.579
2008 Trayanova NA. The long and the short of long and short duration ventricular fibrillation. Circulation Research. 102: 1151-2. PMID 18497314 DOI: 10.1161/Circresaha.108.177303  0.424
2008 Li W, Gurev V, McCulloch AD, Trayanova NA. The role of mechanoelectric feedback in vulnerability to electric shock. Progress in Biophysics and Molecular Biology. 97: 461-78. PMID 18374394 DOI: 10.1016/J.Pbiomolbio.2008.02.020  0.434
2008 Ashihara T, Constantino J, Trayanova NA. Tunnel propagation of postshock activations as a hypothesis for fibrillation induction and isoelectric window. Circulation Research. 102: 737-45. PMID 18218982 DOI: 10.1161/Circresaha.107.168112  0.377
2008 Plank G, Prassl A, Hofer E, Trayanova NA. Evaluating intramural virtual electrodes in the myocardial wedge preparation: simulations of experimental conditions. Biophysical Journal. 94: 1904-15. PMID 17993491 DOI: 10.1529/Biophysj.107.121343  0.324
2008 Maharaj T, Blake R, Trayanova N, Gavaghan D, Rodriguez B. The role of transmural ventricular heterogeneities in cardiac vulnerability to electric shocks. Progress in Biophysics and Molecular Biology. 96: 321-38. PMID 17915299 DOI: 10.1016/J.Pbiomolbio.2007.07.017  0.423
2008 Lalani GG, Bayer J, Trayanova NA, Narayan SM. Action Potential Dynamics Explain Arrhythmic Susceptibility in Systolic Heart Failure Journal of Cardiac Failure. 14: S8-S9. DOI: 10.1016/J.Cardfail.2008.06.033  0.695
2007 Bishop MJ, Gavaghan DJ, Trayanova NA, Rodriguez B. Photon scattering effects in optical mapping of propagation and arrhythmogenesis in the heart. Journal of Electrocardiology. 40: S75-80. PMID 17993334 DOI: 10.1016/J.Jelectrocard.2007.06.020  0.305
2007 Bishop MJ, Rodriguez B, Qu F, Efimov IR, Gavaghan DJ, Trayanova NA. The role of photon scattering in optical signal distortion during arrhythmia and defibrillation. Biophysical Journal. 93: 3714-26. PMID 17978166 DOI: 10.1529/Biophysj.107.110981  0.332
2007 Tice BM, Rodríguez B, Eason J, Trayanova N. Mechanistic investigation into the arrhythmogenic role of transmural heterogeneities in regional ischaemia phase 1A. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. 9: vi46-58. PMID 17959693 DOI: 10.1093/Europace/Eum204  0.771
2007 Trayanova N. Drawing the curtain on the isoelectric window? Heart Rhythm. 4: 766-7. PMID 17556200 DOI: 10.1016/J.Hrthm.2007.03.010  0.405
2007 Komendantov AO, Trayanova NA, Tasker JG. Somato-dendritic mechanisms underlying the electrophysiological properties of hypothalamic magnocellular neuroendocrine cells: a multicompartmental model study. Journal of Computational Neuroscience. 23: 143-68. PMID 17484044 DOI: 10.1007/S10827-007-0024-Z  0.308
2007 Arevalo H, Rodriguez B, Trayanova N. Arrhythmogenesis in the heart: Multiscale modeling of the effects of defibrillation shocks and the role of electrophysiological heterogeneity. Chaos (Woodbury, N.Y.). 17: 015103. PMID 17411260 DOI: 10.1063/1.2430637  0.453
2006 Maharaj T, Rodriguez B, Blake R, Trayanova NA, Gavaghan DJ. Transmural electrophysiological heterogeneities in action potential duration increase the upper limit of vulnerability. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 1: 4043-6. PMID 17946217 DOI: 10.1109/IEMBS.2006.259345  0.349
2006 Rodríguez B, Tice B, Blake R, Gavaghan D, Trayanova N. Vulnerability to electric shocks in the regionally-ischemic ventricles. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 1: 2280-3. PMID 17946101 DOI: 10.1109/IEMBS.2006.259919  0.806
2006 Jie X, Rodriguez B, Trayanova N. Role of cellular uncoupling in arrhythmogenesis in ischemia phase 1B Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Conference. 2272-2275. PMID 17945702 DOI: 10.1109/IEMBS.2006.259470  0.509
2006 Rodríguez B, Trayanova N, Noble D. Modeling cardiac ischemia. Annals of the New York Academy of Sciences. 1080: 395-414. PMID 17132797 DOI: 10.1196/Annals.1380.029  0.446
2006 Gurev V, Maleckar MM, Trayanova NA. Cardiac defibrillation and the role of mechanoelectric feedback in postshock arrhythmogenesis. Annals of the New York Academy of Sciences. 1080: 320-33. PMID 17132792 DOI: 10.1196/Annals.1380.024  0.711
2006 Burton RA, Plank G, Schneider JE, Grau V, Ahammer H, Keeling SL, Lee J, Smith NP, Gavaghan D, Trayanova N, Kohl P. Three-dimensional models of individual cardiac histoanatomy: tools and challenges. Annals of the New York Academy of Sciences. 1080: 301-19. PMID 17132791 DOI: 10.1196/Annals.1380.023  0.417
2006 Trayanova N, Plank G, Rodríguez B. What have we learned from mathematical models of defibrillation and postshock arrhythmogenesis? Application of bidomain simulations. Heart Rhythm. 3: 1232-5. PMID 17018358 DOI: 10.1016/J.Hrthm.2006.04.015  0.433
2006 Bishop MJ, Rodriguez B, Trayanova N, Gavaghan DJ. Inference of intramural wavefront orientation from optical recordings in realistic whole-heart models. Biophysical Journal. 91: 3957-8. PMID 16935956 DOI: 10.1529/Biophysj.106.092544  0.307
2006 Kuo SR, Trayanova NA. Action potential morphology heterogeneity in the atrium and its effect on atrial reentry: a two-dimensional and quasi-three-dimensional study. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 364: 1349-66. PMID 16766349 DOI: 10.1098/Rsta.2006.1776  0.325
2006 Bourn DW, Maleckar MM, Rodriguez B, Trayanova NA. Mechanistic enquiry into the effect of increased pacing rate on the upper limit of vulnerability. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 364: 1333-48. PMID 16766348 DOI: 10.1098/Rsta.2006.1775  0.786
2006 Bourn DW, Gray RA, Trayanova NA. Characterization of the relationship between preshock state and virtual electrode polarization-induced propagated graded responses resulting in arrhythmia induction. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 3: 583-95. PMID 16648066 DOI: 10.1016/J.Hrthm.2006.01.024  0.743
2006 Trayanova N. Defibrillation of the heart: insights into mechanisms from modelling studies. Experimental Physiology. 91: 323-37. PMID 16469820 DOI: 10.1113/Expphysiol.2005.030973  0.448
2006 Bishop MJ, Rodriguez B, Eason J, Whiteley JP, Trayanova N, Gavaghan DJ. Synthesis of voltage-sensitive optical signals: application to panoramic optical mapping. Biophysical Journal. 90: 2938-45. PMID 16443665 DOI: 10.1529/Biophysj.105.076505  0.314
2006 Li W, Kohl P, Trayanova N. Myocardial ischemia lowers precordial thump efficacy: an inquiry into mechanisms using three-dimensional simulations. Heart Rhythm. 3: 179-86. PMID 16443533 DOI: 10.1016/J.Hrthm.2005.10.033  0.386
2006 Rodríguez B, Eason JC, Trayanova N. Differences between left and right ventricular anatomy determine the types of reentrant circuits induced by an external electric shock. A rabbit heart simulation study. Progress in Biophysics and Molecular Biology. 90: 399-413. PMID 16055175 DOI: 10.1016/J.Pbiomolbio.2005.06.008  0.401
2006 Gurev V, Blake RC, Trayanova NA. P6-28: Myocardial stretch alters the pattern of post-shock activity Heart Rhythm. 3. DOI: 10.1016/J.Hrthm.2006.02.929  0.31
2006 Bourn DW, Gray RA, Trayanova NA. P5-9: Virtual electrode-induced propagated graded responses and arrhythmogenesis Heart Rhythm. 3. DOI: 10.1016/J.Hrthm.2006.02.787  0.717
2006 Rodriguez B, Tice B, Blake RC, Eason J, Gavaghan D, Trayanova NA. P4-24 Heart Rhythm. 3: S226. DOI: 10.1016/J.Hrthm.2006.02.679  0.742
2006 Maleckar MM, Blake RC, Trayanova NA. P3-27 Heart Rhythm. 3: S187. DOI: 10.1016/J.Hrthm.2006.02.559  0.624
2006 Maharaj T, Rodriguez B, Blake R, Trayanova NA, Gavaghan DJ. Mechanisms underlying cardiac vulnerability to electric shocks within the three-dimensional volume of the rabbit ventricles Computers in Cardiology. 33: 37-40.  0.31
2005 Jie X, Rodriguez B, Trayanova N. The ischemic heart: what causes ectopic beating? Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 7: 7194-7. PMID 17281937 DOI: 10.1109/IEMBS.2005.1616168  0.582
2005 Ashihara T, Trayanova NA. Cell and tissue responses to electric shocks. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. 7: 155-65. PMID 16102513 DOI: 10.1016/J.Eupc.2005.03.020  0.335
2005 Rodríguez B, Li L, Eason JC, Efimov IR, Trayanova NA. Differences between left and right ventricular chamber geometry affect cardiac vulnerability to electric shocks. Circulation Research. 97: 168-75. PMID 15976315 DOI: 10.1161/01.Res.0000174429.00987.17  0.411
2005 Li W, Kohl P, Trayanova N. Induction of ventricular arrhythmias following mechanical impact: a simulation study in 3D. Journal of Molecular Histology. 35: 679-86. PMID 15614623 DOI: 10.1007/S10735-004-2666-8  0.378
2005 Tice BM, Rodriguez B, Trayanova NA. Arrthythmogenicity of transmural heterogeneities in a realistic model of regional ischemia Heart Rhythm. 2: S261. DOI: 10.1016/J.Hrthm.2005.02.820  0.773
2005 Rodriguez B, Li L, Eason JC, Efimov IR, Trayanova NA. Role of ventricular anatomy in vulnerability to electric shocks Heart Rhythm. 2: S257. DOI: 10.1016/J.Hrthm.2005.02.806  0.344
2005 Li W, Kohl P, Trayanova NA. Myocardial ischemia lowers precordial thump efficacy: An inquiry into mechanisms using 3D simulations Heart Rhythm. 2. DOI: 10.1016/J.Hrthm.2005.02.685  0.318
2005 Maleckar MM, Bourn DW, Rodriguez B, Trayanova NA. Mechanistic insight into the increase in the upper limit of vulnerability for rapid pacing Heart Rhythm. 2: S219. DOI: 10.1016/J.Hrthm.2005.02.684  0.76
2004 Rodríguez B, Tice BM, Eason JC, Aguel F, Trayanova N. Cardiac vulnerability to electric shocks during phase 1A of acute global ischemia. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 1: 695-703. PMID 15851241 DOI: 10.1016/J.Hrthm.2004.08.018  0.781
2004 Vigmond EJ, Tsoi V, Kuo S, Arevalo H, Kneller J, Nattel S, Trayanova N. The effect of vagally induced dispersion of action potential duration on atrial arrhythmogenesis. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 1: 334-44. PMID 15851180 DOI: 10.1016/J.Hrthm.2004.03.077  0.317
2004 Ashihara T, Trayanova NA. Asymmetry in membrane responses to electric shocks: insights from bidomain simulations. Biophysical Journal. 87: 2271-82. PMID 15454429 DOI: 10.1529/Biophysj.104.043091  0.34
2004 Ashihara T, Namba T, Ito M, Ikeda T, Nakazawa K, Trayanova N. Spiral wave control by a localized stimulus: a bidomain model study. Journal of Cardiovascular Electrophysiology. 15: 226-33. PMID 15028055 DOI: 10.1046/J.1540-8167.2004.03381.X  0.316
2004 Ashihara T, Namba T, Ikeda T, Ito M, Nakazawa K, Trayanova N. Mechanisms of myocardial capture and temporal excitable gap during spiral wave reentry in a bidomain model. Circulation. 109: 920-5. PMID 14967721 DOI: 10.1161/01.Cir.0000118331.13524.75  0.354
2004 Rodríguez B, Tice BM, Eason JC, Aguel F, Ferrero JM, Trayanova N. Effect of acute global ischemia on the upper limit of vulnerability: a simulation study. American Journal of Physiology. Heart and Circulatory Physiology. 286: H2078-88. PMID 14751853 DOI: 10.1152/Ajpheart.01175.2003  0.797
2004 Rodríguez B, Trayanova N. Upper limit of vulnerability in a defibrillation model of the rabbit ventricles. Journal of Electrocardiology. 51-6. PMID 14716592 DOI: 10.1016/J.Jelectrocard.2003.09.066  0.388
2004 Hillebrenner MG, Eason JC, Trayanova NA. Mechanistic inquiry into decrease in probability of defibrillation success with increase in complexity of preshock reentrant activity. American Journal of Physiology. Heart and Circulatory Physiology. 286: H909-17. PMID 14604852 DOI: 10.1152/Ajpheart.00492.2003  0.348
2004 Larson C, Dragnev L, Trayanova N. Analysis of electrically induced reentrant circuits in a sheet of myocardium. Annals of Biomedical Engineering. 31: 768-80. PMID 12971610 DOI: 10.1114/1.1581289  0.32
2003 Hillebrenner MG, Eason JC, Campbell CA, Trayanova NA. Postshock arrhythmogenesis in a slice of the canine heart. Journal of Cardiovascular Electrophysiology. 14: S249-56. PMID 14760930 DOI: 10.1046/J.1540.8167.90317.X  0.349
2003 Trayanova NA, Gray RA, Bourn DW, Eason JC. Virtual electrode-induced positive and negative graded responses: new insights into fibrillation induction and defibrillation. Journal of Cardiovascular Electrophysiology. 14: 756-63. PMID 12930258 DOI: 10.1046/J.1540-8167.2003.03042.X  0.742
2003 Atkinson EM, Trayanova NA. Contact probes for MAP recording: A computational study Journal of Biological Systems. 11: 139-160. DOI: 10.1142/S0218339003000804  0.308
2003 AGUEL F, EASON J, TRAYANOVA N. ADVANCES IN MODELING CARDIAC DEFIBRILLATION International Journal of Bifurcation and Chaos. 13: 3791-3803. DOI: 10.1142/S0218127403008892  0.473
2002 Meunier JM, Eason JC, Trayanova NA. Termination of reentry by a long-lasting AC shock in a slice of canine heart: a computational study. Journal of Cardiovascular Electrophysiology. 13: 1253-61. PMID 12521342 DOI: 10.1046/J.1540-8167.2002.01253.X  0.396
2002 Trayanova NA. Are we closer to understanding defibrillation in the whole heart? Journal of Cardiovascular Electrophysiology. 13: 1128-30. PMID 12475104 DOI: 10.1046/J.1540-8167.2002.01128.X  0.381
2002 Skouibine K, Wall J, Krassowska W, Trayanova N. Modelling induction of a rotor in cardiac muscle by perpendicular electric shocks. Medical & Biological Engineering & Computing. 40: 47-55. PMID 11954708 DOI: 10.1007/Bf02347695  0.385
2002 Vigmond EJ, Ruckdeschel R, Trayanova N. Reentry in a morphologically realistic atrial model. Journal of Cardiovascular Electrophysiology. 12: 1046-54. PMID 11577703 DOI: 10.1046/J.1540-8167.2001.01046.X  0.388
2002 Trayanova N, Eason J, Aguel F. Computer simulations of cardiac defibrillation: a look inside the heart Computing and Visualization in Science. 4: 259-270. DOI: 10.1007/S00791-002-0082-8  0.471
2002 Aguel F, Campbell CA, Trayanova NA. Biphasic defibrillation in a model of the rabbit heart Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 2: 1424-1425.  0.308
2001 Anderson C, Trayanova NA. Success and failure of biphasic shocks: Results of bidomain simulations Mathematical Biosciences. 174: 91-109. PMID 11730859 DOI: 10.1016/S0025-5564(01)00076-1  0.334
2001 Meunier JM, Trayanova NA, Gray RA. Entrainment by an extracellular AC stimulus in a computational model of cardiac tissue Journal of Cardiovascular Electrophysiology. 12: 1176-1184. PMID 11699528 DOI: 10.1046/J.1540-8167.2001.01176.X  0.393
2001 Vigmond EJ, Trayanova NA, Malkin RA. Excitation of a cardiac muscle fiber by extracellularly applied sinusoidal current Journal of Cardiovascular Electrophysiology. 12: 1145-1153. PMID 11699523 DOI: 10.1046/J.1540-8167.2001.01145.X  0.394
2001 Gray RA, Huelsing DJ, Aguel F, Trayanova NA. Effect of strength and timing of transmembrane current pulses on isolated ventricular myocytes Journal of Cardiovascular Electrophysiology. 12: 1129-1137. PMID 11699521 DOI: 10.1046/J.1540-8167.2001.01129.X  0.346
2001 Lindblom AE, Aguel F, Trayanova NA. Virtual electrode polarization leads to reentry in the far field Journal of Cardiovascular Electrophysiology. 12: 946-956. PMID 11513448 DOI: 10.1046/J.1540-8167.2001.00946.X  0.326
2001 Anderson C, Trayanova N, Skouibine K. Termination of spiral waves with biphasic shocks: role of virtual electrode polarization. Journal of Cardiovascular Electrophysiology. 11: 1386-96. PMID 11196563 DOI: 10.1046/J.1540-8167.2000.01386.X  0.319
2001 Trayanova N. Concepts of ventricular defibrillation Philosophical Transactions of the Royal Society of London. Series a: Mathematical, Physical and Engineering Sciences. 359: 1327-1337. DOI: 10.1098/Rsta.2001.0834  0.395
2001 Eason JC, Trayanova NA. Phase singularities and termination of spiral wave reentry Annual Reports of the Research Reactor Institute, Kyoto University. 1: 66-69. DOI: 10.1046/J.1540-8167.2002.00672.X  0.312
2000 Efimov IR, Aguel F, Cheng Y, Wollenzier B, Trayanova N. Virtual electrode polarization in the far field: Implications for external defibrillation American Journal of Physiology - Heart and Circulatory Physiology. 279. PMID 10993768 DOI: 10.1152/Ajpheart.2000.279.3.H1055  0.37
2000 Skouibine K, Trayanova N, Moore P. Success and failure of the defibrillation shock: insights from a simulation study. Journal of Cardiovascular Electrophysiology. 11: 785-796. PMID 10921796 DOI: 10.1111/J.1540-8167.2000.Tb00050.X  0.383
2000 Skouibine K, Trayanova N, Moore P. A numerically efficient model for simulation of defibrillation in an active bidomain sheet of myocardium. Bellman Prize in Mathematical Biosciences. 166: 85-100. PMID 10882801 DOI: 10.1016/S0025-5564(00)00019-5  0.36
2000 Lindblom AE, Roth BJ, Trayanova NA. Role of virtual electrodes in arrhythmogenesis: Pinwheel experiment revisited Journal of Cardiovascular Electrophysiology. 11: 274-285. PMID 10749350 DOI: 10.1111/J.1540-8167.2000.Tb01796.X  0.345
1999 Meunier JM, Trayanova NA, Gray RA. Sinusoidal stimulation of myocardial tissue: Effects on single cells Journal of Cardiovascular Electrophysiology. 10: 1619-1630. PMID 10636192 DOI: 10.1111/J.1540-8167.1999.Tb00226.X  0.378
1999 Skouibine KB, Trayanova NA, Moore PK. Anode/cathode make and break phenomena in a model of defibrillation Ieee Transactions On Biomedical Engineering. 46: 769-777. PMID 10396895 DOI: 10.1109/10.771186  0.342
1999 Trayanova NA, Aguel F, Skouibine K. Extension of refractoriness in a model of cardiac defibrillation Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 240-251. PMID 10380201  0.316
1999 Aguel F, Debruin KA, Krassowska W, Trayanova NA. Effects of electroporation on the transmembrane potential distribution in a two-dimensional bidomain model of cardiac tissue Journal of Cardiovascular Electrophysiology. 10: 701-714. PMID 10355926 DOI: 10.1111/J.1540-8167.1999.Tb00247.X  0.302
1999 Aguel F, Eason JC, Trayanova NA, Siekas G, Fishler MG. Impact of transvenous lead position on active-can ICD defibrillation: A computer simulation study Pace - Pacing and Clinical Electrophysiology. 22: 158-164. PMID 9990622 DOI: 10.1111/J.1540-8159.1999.Tb00324.X  0.372
1999 Trayanova N. Far-field stimulation of cardiac tissue Herzschrittmachertherapie Und Elektrophysiologie. 10: 137-148. DOI: 10.1007/S003990050055  0.304
1999 Wall J, Trayanova NA, Skouibine K, Krassowska W. Modeling induction of reentry with a realistic S2 stimulus Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 154.  0.33
1998 Trayanova N, Skouibine K. Modeling defibrillation: effects of fiber curvature. Journal of Electrocardiology. 31: 23-29. PMID 9988001 DOI: 10.1016/S0022-0736(98)90274-6  0.328
1998 Trayanova N, Skouibine K, Moore P. Virtual electrode effects in defibrillation Progress in Biophysics & Molecular Biology. 69: 387-403. PMID 9785947 DOI: 10.1016/S0079-6107(98)00016-9  0.346
1998 Eason J, Schmidt J, Dabasinskas A, Siekas G, Aguel F, Trayanova N. Influence of anisotropy on local and global measures of potential gradient in computer models of defibrillation. Annals of Biomedical Engineering. 26: 840-9. PMID 9779957 DOI: 10.1114/1.68  0.434
1997 Trayanova NA. Effects of the tissue-bath interface on the induced transmembrane potential: A modeling study in cardiac stimulation Annals of Biomedical Engineering. 25: 783-792. PMID 9300102 DOI: 10.1007/Bf02684162  0.365
1997 Trayanova N, Bray BSM. Membrane Refractoriness and Excitation Induced in Cardiac Fibers by Monophasic and Biphasic Shocks Journal of Cardiovascular Electrophysiology. 8: 745-757. PMID 9255682 DOI: 10.1111/J.1540-8167.1997.Tb00833.X  0.332
1996 Trayanova N. Discrete versus syncytial tissue behavior in a model of cardiac stimulation. II. Results of simulation Ieee Transactions On Biomedical Engineering. 43: 1141-1150. PMID 9214833 DOI: 10.1109/10.544338  0.417
1996 Trayanova N. Discrete versus syncytial tissue behavior in a model of cardiac stimulation. I. Mathematical formulation Ieee Transactions On Biomedical Engineering. 43: 1129-1140. PMID 9214832 DOI: 10.1109/10.544337  0.365
1994 Trayanova N. A bidomain model for ring stimulation of a cardiac strand Ieee Transactions On Biomedical Engineering. 41: 393-397. PMID 8063307 DOI: 10.1109/10.284970  0.356
1993 Trayanova NA, Roth BJ, Maiden LJ. The Response of a Spherical Heart to a Uniform Electric Field: A Bidomain Analysis of Cardiac Stimulation Ieee Transactions On Biomedical Engineering. 40: 899-908. PMID 8288281 DOI: 10.1109/10.245611  0.391
1993 Trayanova N, Pilkington TC. A bidomain model with periodic intracellular junctions: a one-dimensional analysis Ieee Transactions On Biomedical Engineering. 40: 424-433. PMID 8225331 DOI: 10.1109/10.243419  0.36
1991 Trayanova N, Henriquez CS. Modification of a cylindrical bidomain model for cardiac tissue Mathematical Biosciences. 104: 59-72. PMID 1804456 DOI: 10.1016/0025-5564(91)90030-M  0.405
1990 Henriquez CS, Trayanova N, Plonsey R. A planar slab bidomain model for cardiac tissue Annals of Biomedical Engineering. 18: 367-376. PMID 2221506 DOI: 10.1007/Bf02364155  0.406
1988 Henriquez CS, Trayanova N, Plonsey R. Potential and current distributions in a cylindrical bundle of cardiac tissue Biophysical Journal. 53: 907-918. PMID 3395660 DOI: 10.1016/S0006-3495(88)83172-2  0.327
1988 Plonsey R, Henriquez C, Trayanova N. Extracellular (volume conductor) effect on adjoining cardiac muscle electrophysiology. Medical & Biological Engineering & Computing. 26: 126-129. PMID 3226166 DOI: 10.1007/Bf02442253  0.314
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