| Year |
Citation |
Score |
| 2023 |
O'Brien S, Ubhi T, Wolf L, Gandhi K, Lin S, Chaudary N, Dhani NC, Milosevic M, Brown GW, Angers S. FBXW7-loss sensitizes cells to ATR inhibition through induced mitotic catastrophe. Cancer Research Communications. PMID 38032106 DOI: 10.1158/2767-9764.CRC-23-0306 |
0.425 |
|
| 2023 |
Jiang YK, Medley EA, Brown GW. Two independent DNA repair pathways cause mutagenesis in template switching deficient Saccharomyces cerevisiae. Genetics. PMID 37594077 DOI: 10.1093/genetics/iyad153 |
0.44 |
|
| 2023 |
Ho B, Sanford EJ, Loll-Krippleber R, Torres NP, Smolka MB, Brown GW. Mec1-independent activation of the Rad53 checkpoint kinase revealed by quantitative analysis of protein localization dynamics. Elife. 12. PMID 37278514 DOI: 10.7554/eLife.82483 |
0.418 |
|
| 2022 |
Tamayo-Orrego L, Gallo D, Racicot F, Bemmo A, Mohan S, Ho B, Salameh S, Hoang T, Jackson AP, Brown GW, Charron F. Author Correction: Sonic hedgehog accelerates DNA replication to cause replication stress promoting cancer initiation in medulloblastoma. Nature Cancer. 2: 575. PMID 35430602 DOI: 10.1038/s43018-021-00205-9 |
0.378 |
|
| 2022 |
Wang Y, Huang Y, Cheng E, Liu X, Zhang Y, Yang J, Young JTF, Brown GW, Yang X, Shang Y. LSD1 is required for euchromatic origin firing and replication timing. Signal Transduction and Targeted Therapy. 7: 102. PMID 35414135 DOI: 10.1038/s41392-022-00927-x |
0.471 |
|
| 2021 |
Galati E, Bosio MC, Novarina D, Chiara M, Bernini GM, Mozzarelli AM, García-Rubio ML, Gómez-González B, Aguilera A, Carzaniga T, Todisco M, Bellini T, Nava GM, Frigè G, Sertic S, ... ... Brown GW, et al. VID22 counteracts G-quadruplex-induced genome instability. Nucleic Acids Research. PMID 34871443 DOI: 10.1093/nar/gkab1156 |
0.478 |
|
| 2021 |
Ayra-Plasencia J, Ramos-Pérez C, Santana-Sosa S, Quevedo O, Medina-Suárez S, Matos-Perdomo E, Zamora-Dorta M, Brown GW, Lisby M, Machín F. Topoisomerase II deficiency leads to a postreplicative structural shift in all Saccharomyces cerevisiae chromosomes. Scientific Reports. 11: 14940. PMID 34294749 DOI: 10.1038/s41598-021-93875-5 |
0.329 |
|
| 2020 |
Tamayo-Orrego L, Gallo D, Racicot F, Bemmo A, Mohan S, Ho B, Salameh S, Hoang T, Jackson AP, Brown GW, Charron F. Sonic hedgehog accelerates DNA replication to cause replication stress promoting cancer initiation in medulloblastoma. Nature Cancer. 1: 840-854. PMID 35122047 DOI: 10.1038/s43018-020-0094-7 |
0.356 |
|
| 2020 |
Olivieri M, Cho T, Álvarez-Quilón A, Li K, Schellenberg MJ, Zimmermann M, Hustedt N, Rossi SE, Adam S, Melo H, Heijink AM, Sastre-Moreno G, Moatti N, Szilard RK, McEwan A, ... ... Brown GW, et al. A Genetic Map of the Response to DNA Damage in Human Cells. Cell. PMID 32649862 DOI: 10.1016/J.Cell.2020.05.040 |
0.504 |
|
| 2020 |
Zhu Y, Berg MD, Yang P, Loll-Krippleber R, Brown GW, Brandl CJ. Mistranslating tRNA identifies a deleterious S213P mutation in the Saccharomyces cerevisiae eco1-1 allele. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. PMID 32476470 DOI: 10.1139/Bcb-2020-0151 |
0.307 |
|
| 2020 |
Novarina D, Desai R, Vaisica JA, Ou J, Bellaoui M, Brown GW, Chang M. A Genome-Wide Screen for Genes Affecting Spontaneous Direct-Repeat Recombination in . G3 (Bethesda, Md.). PMID 32265288 DOI: 10.1534/G3.120.401137 |
0.781 |
|
| 2020 |
Tamayo-Orrego L, Gallo D, Racicot F, Bemmo A, Mohan S, Ho B, Salameh S, Hoang T, Jackson AP, Brown GW, Charron F. Sonic hedgehog accelerates DNA replication to cause replication stress promoting cancer initiation in medulloblastoma Nature Cancer. 1: 840-854. DOI: 10.1038/s43018-020-0094-7 |
0.389 |
|
| 2019 |
Gallo D, Brown GW. Post-replication repair: Rad5/HLTF regulation, activity on undamaged templates, and relationship to cancer. Critical Reviews in Biochemistry and Molecular Biology. 1-32. PMID 31429594 DOI: 10.1080/10409238.2019.1651817 |
0.517 |
|
| 2019 |
Ubhi T, Brown GW. Exploiting DNA Replication Stress for Cancer Treatment. Cancer Research. PMID 30967400 DOI: 10.1158/0008-5472.Can-18-3631 |
0.443 |
|
| 2019 |
Gallo D, Kim T, Szakal B, Saayman X, Narula A, Park Y, Branzei D, Zhang Z, Brown GW. Rad5 Recruits Error-Prone DNA Polymerases for Mutagenic Repair of ssDNA Gaps on Undamaged Templates. Molecular Cell. PMID 30733119 DOI: 10.1016/J.Molcel.2019.01.001 |
0.519 |
|
| 2019 |
Tamayo-Orrego L, Gallo D, Bemmo A, Mohan S, Salameh S, Racicot F, Brown G, Charron F. MEDU-46. SONIC HEDGEHOG SPEEDS UP DNA REPLICATION AND CAUSES CANCER-INITIATING MUTATIONS Neuro-Oncology. 21: ii113-ii113. DOI: 10.1093/Neuonc/Noz036.204 |
0.445 |
|
| 2018 |
Sing TL, Hung MP, Ohnuki S, Suzuki G, San Luis BJ, McClain M, Unruh JR, Yu Z, Ou J, Marshall-Sheppard J, Huh WK, Costanzo M, Boone C, Ohya Y, Jaspersen SL, ... Brown GW, et al. The budding yeast RSC complex maintains ploidy by promoting spindle pole body insertion. The Journal of Cell Biology. PMID 29875260 DOI: 10.1083/Jcb.201709009 |
0.497 |
|
| 2018 |
Díaz-Mejía JJ, Celaj A, Mellor JC, Coté A, Balint A, Ho B, Bansal P, Shaeri F, Gebbia M, Weile J, Verby M, Karkhanina A, Zhang Y, Wong C, Rich J, ... ... Brown GW, et al. Mapping DNA damage-dependent genetic interactions in yeast via party mating and barcode fusion genetics. Molecular Systems Biology. 14: e7985. PMID 29807908 DOI: 10.15252/Msb.20177985 |
0.463 |
|
| 2018 |
Becker JR, Gallo D, Leung W, Croissant T, Thu YM, Nguyen HD, Starr TK, Brown GW, Bielinsky AK. Flap endonuclease overexpression drives genome instability and DNA damage hypersensitivity in a PCNA-dependent manner. Nucleic Acids Research. PMID 29741650 DOI: 10.1093/Nar/Gky313 |
0.58 |
|
| 2018 |
Kuzmin E, VanderSluis B, Wang W, Tan G, Deshpande R, Chen Y, Usaj M, Balint A, Mattiazzi Usaj M, van Leeuwen J, Koch EN, Pons C, Dagilis AJ, Pryszlak M, Wang JZY, ... ... Brown GW, et al. Systematic analysis of complex genetic interactions. Science (New York, N.Y.). 360. PMID 29674565 DOI: 10.1126/Science.Aao1729 |
0.33 |
|
| 2018 |
Ho B, Baryshnikova A, Brown GW. Unification of Protein Abundance Datasets Yields a Quantitative Saccharomyces cerevisiae Proteome. Cell Systems. PMID 29361465 DOI: 10.1016/J.Cels.2017.12.004 |
0.304 |
|
| 2018 |
Saayman X, Ramos-Pérez C, Brown GW. DNA Replication Profiling Using Deep Sequencing. Methods in Molecular Biology (Clifton, N.J.). 1672: 195-207. PMID 29043626 DOI: 10.1007/978-1-4939-7306-4_15 |
0.526 |
|
| 2017 |
Loll-Krippleber R, Brown GW. P-body proteins regulate transcriptional rewiring to promote DNA replication stress resistance. Nature Communications. 8: 558. PMID 28916784 DOI: 10.1038/S41467-017-00632-2 |
0.395 |
|
| 2017 |
Ramos-Pérez C, Ayra-Plasencia J, Matos-Perdomo E, Lisby M, Brown GW, Machín F. Genome-Scale Genetic Interactions and Cell Imaging Confirm Cytokinesis as Deleterious to Transient Topoisomerase II Deficiency in Saccharomyces cerevisiae. G3 (Bethesda, Md.). PMID 28839115 DOI: 10.1534/G3.117.300104 |
0.443 |
|
| 2017 |
Wheaton K, Campuzano D, Ma W, Sheinis M, Ho B, Brown GW, Benchimol S. Progerin-Induced Replication Stress Facilitates Premature Senescence in Hutchinson Gilford Progeria Syndrome. Molecular and Cellular Biology. PMID 28483909 DOI: 10.1128/Mcb.00659-16 |
0.545 |
|
| 2017 |
Xu H, Di Antonio M, McKinney S, Mathew V, Ho B, O'Neil NJ, Santos ND, Silvester J, Wei V, Garcia J, Kabeer F, Lai D, Soriano P, Banáth J, Chiu DS, ... ... Brown GW, et al. CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours. Nature Communications. 8: 14432. PMID 28211448 DOI: 10.1038/Ncomms14432 |
0.46 |
|
| 2016 |
Styles EB, Founk KJ, Zamparo LA, Sing TL, Altintas D, Ribeyre C, Ribaud V, Rougemont J, Mayhew D, Costanzo M, Usaj M, Verster AJ, Koch EN, Novarina D, Graf M, ... ... Brown GW, et al. Exploring Quantitative Yeast Phenomics with Single-Cell Analysis of DNA Damage Foci. Cell Systems. PMID 27617677 DOI: 10.1016/J.Cels.2016.08.008 |
0.545 |
|
| 2016 |
Abraham KJ, Chan JN, Salvi JS, Ho B, Hall A, Vidya E, Guo R, Killackey SA, Liu N, Lee JE, Brown GW, Mekhail K. Intersection of calorie restriction and magnesium in the suppression of genome-destabilizing RNA-DNA hybrids. Nucleic Acids Research. PMID 27574117 DOI: 10.1093/Nar/Gkw752 |
0.352 |
|
| 2016 |
Bonner JN, Choi K, Xue X, Torres NP, Szakal B, Wei L, Wan B, Arter M, Matos J, Sung P, Brown GW, Branzei D, Zhao X. Smc5/6 Mediated Sumoylation of the Sgs1-Top3-Rmi1 Complex Promotes Removal of Recombination Intermediates. Cell Reports. PMID 27373152 DOI: 10.1016/J.Celrep.2016.06.015 |
0.538 |
|
| 2016 |
Yimit A, Kim T, Anand R, Meister S, Ou J, Haber JE, Zhang Z, Brown GW. MTE1 Functions with MPH1 in Double-Strand Break Repair. Genetics. PMID 26920759 DOI: 10.1534/Genetics.115.185454 |
0.572 |
|
| 2016 |
Torres NP, Ho B, Brown GW. High-throughput fluorescence microscopic analysis of protein abundance and localization in budding yeast. Critical Reviews in Biochemistry and Molecular Biology. 1-10. PMID 26893079 DOI: 10.3109/10409238.2016.1145185 |
0.347 |
|
| 2016 |
Gallo D, Wang G, Yip CM, Brown GW. Single-Molecule Analysis of Replicating Yeast Chromosomes. Cold Spring Harbor Protocols. 2016: pdb.top077784. PMID 26832692 DOI: 10.1101/Pdb.Top077784 |
0.508 |
|
| 2016 |
Gallo D, Wang G, Yip CM, Brown GW. Analysis of Replicating Yeast Chromosomes by DNA Combing. Cold Spring Harbor Protocols. 2016: pdb.prot085118. PMID 26832684 DOI: 10.1101/Pdb.Prot085118 |
0.551 |
|
| 2016 |
Tkáč J, Xu G, Adhikary H, Young JT, Gallo D, Escribano-Díaz C, Krietsch J, Orthwein A, Munro M, Sol W, Al-Hakim A, Lin ZY, Jonkers J, Borst P, Brown GW, et al. HELB Is a Feedback Inhibitor of DNA End Resection. Molecular Cell. PMID 26774285 DOI: 10.1016/J.Molcel.2015.12.013 |
0.504 |
|
| 2015 |
Dibitetto D, Ferrari M, Rawal CC, Balint A, Kim T, Zhang Z, Smolka MB, Brown GW, Marini F, Pellicioli A. Slx4 and Rtt107 control checkpoint signalling and DNA resection at double-strand breaks. Nucleic Acids Research. PMID 26490958 DOI: 10.1093/Nar/Gkv1080 |
0.576 |
|
| 2015 |
Jablonowski CM, Cussiol JR, Oberly S, Yimit A, Balint A, Kim T, Zhang Z, Brown GW, Smolka MB. Termination of Replication Stress Signaling via Concerted Action of the Slx4 Scaffold and the PP4 Phosphatase. Genetics. PMID 26362319 DOI: 10.1534/Genetics.115.181479 |
0.552 |
|
| 2015 |
Yimit A, Riffle M, Brown GW. Genetic Regulation of Dna2 Localization During the DNA Damage Response. G3 (Bethesda, Md.). 5: 1937-44. PMID 26163422 DOI: 10.1534/G3.115.019208 |
0.566 |
|
| 2015 |
Balint A, Kim T, Gallo D, Cussiol JR, Bastos de Oliveira FM, Yimit A, Ou J, Nakato R, Gurevich A, Shirahige K, Smolka MB, Zhang Z, Brown GW. Assembly of Slx4 signaling complexes behind DNA replication forks. The Embo Journal. PMID 26113155 DOI: 10.15252/Embj.201591190 |
0.546 |
|
| 2015 |
Chaillot J, Tebbji F, Remmal A, Boone C, Brown GW, Bellaoui M, Sellam A. The monoterpene carvacrol generates endoplasmic reticulum stress in the pathogenic fungus Candida albicans. Antimicrobial Agents and Chemotherapy. PMID 26014932 DOI: 10.1128/Aac.00551-15 |
0.372 |
|
| 2015 |
Torres NP, Brown GW. A high-throughput confocal fluorescence microscopy platform to study DNA replication stress in yeast cells. Methods in Molecular Biology (Clifton, N.J.). 1300: 1-12. PMID 25916702 DOI: 10.1007/978-1-4939-2596-4_1 |
0.334 |
|
| 2015 |
Cussiol JR, Jablonowski CM, Yimit A, Brown GW, Smolka MB. Dampening DNA damage checkpoint signalling via coordinated BRCT domain interactions. The Embo Journal. 34: 1704-17. PMID 25896509 DOI: 10.15252/Embj.201490834 |
0.516 |
|
| 2015 |
Grote D, Moison C, Duhamel S, Chagraoui J, Girard S, Yang J, Mayotte N, Coulombe Y, Masson JY, Brown GW, Meloche S, Sauvageau G. E4F1 is a master regulator of CHK1-mediated functions. Cell Reports. 11: 210-9. PMID 25843717 DOI: 10.1016/J.Celrep.2015.03.019 |
0.676 |
|
| 2015 |
Hendry JA, Tan G, Ou J, Boone C, Brown GW. Leveraging DNA damage response signaling to identify yeast genes controlling genome stability. G3 (Bethesda, Md.). 5: 997-1006. PMID 25721128 DOI: 10.1534/G3.115.016576 |
0.5 |
|
| 2014 |
Larin M, Gallo D, Tamblyn L, Yang J, Liao H, Sabat N, Brown GW, McPherson JP. Fanconi anemia signaling and Mus81 cooperate to safeguard development and crosslink repair. Nucleic Acids Research. 42: 9807-20. PMID 25056314 DOI: 10.1093/Nar/Gku676 |
0.626 |
|
| 2014 |
Coschi CH, Ishak CA, Gallo D, Marshall A, Talluri S, Wang J, Cecchini MJ, Martens AL, Percy V, Welch I, Boutros PC, Brown GW, Dick FA. Haploinsufficiency of an RB-E2F1-Condensin II complex leads to aberrant replication and aneuploidy. Cancer Discovery. 4: 840-53. PMID 24740996 DOI: 10.1158/2159-8290.Cd-14-0215 |
0.484 |
|
| 2014 |
Lee AY, St Onge RP, Proctor MJ, Wallace IM, Nile AH, Spagnuolo PA, Jitkova Y, Gronda M, Wu Y, Kim MK, Cheung-Ong K, Torres NP, Spear ED, Han MK, Schlecht U, ... ... Brown GW, et al. Mapping the cellular response to small molecules using chemogenomic fitness signatures. Science (New York, N.Y.). 344: 208-11. PMID 24723613 DOI: 10.1126/Science.1250217 |
0.353 |
|
| 2014 |
Jagannathan M, Nguyen T, Gallo D, Luthra N, Brown GW, Saridakis V, Frappier L. A role for USP7 in DNA replication. Molecular and Cellular Biology. 34: 132-45. PMID 24190967 DOI: 10.1128/Mcb.00639-13 |
0.521 |
|
| 2013 |
Xu D, Shen W, Guo R, Xue Y, Peng W, Sima J, Yang J, Sharov A, Srikantan S, Yang J, Fox D, Qian Y, Martindale JL, Piao Y, Machamer J, ... ... Brown GW, et al. Top3β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation. Nature Neuroscience. 16: 1238-47. PMID 23912945 DOI: 10.1038/Nn.3479 |
0.565 |
|
| 2013 |
Srikumar T, Lewicki MC, Costanzo M, Tkach JM, van Bakel H, Tsui K, Johnson ES, Brown GW, Andrews BJ, Boone C, Giaever G, Nislow C, Raught B. Global analysis of SUMO chain function reveals multiple roles in chromatin regulation. The Journal of Cell Biology. 201: 145-63. PMID 23547032 DOI: 10.1083/Jcb.201210019 |
0.365 |
|
| 2013 |
Grote D, Girard S, Chagraoui J, Yang J, Mayotte N, McRae T, Brown G, Sauvageau G. The Bmi1-interacting protein E4f1 is vital for hematopoietic stem/progenitor cell function Experimental Hematology. 41: S15. DOI: 10.1016/J.Exphem.2013.05.055 |
0.5 |
|
| 2012 |
Chambers AL, Ormerod G, Durley SC, Sing TL, Brown GW, Kent NA, Downs JA. The INO80 chromatin remodeling complex prevents polyploidy and maintains normal chromatin structure at centromeres. Genes & Development. 26: 2590-603. PMID 23207916 DOI: 10.1101/Gad.199976.112 |
0.449 |
|
| 2012 |
Cheung-Ong K, Song KT, Ma Z, Shabtai D, Lee AY, Gallo D, Heisler LE, Brown GW, Bierbach U, Giaever G, Nislow C. Comparative chemogenomics to examine the mechanism of action of dna-targeted platinum-acridine anticancer agents. Acs Chemical Biology. 7: 1892-901. PMID 22928710 DOI: 10.1021/Cb300320D |
0.49 |
|
| 2012 |
Yang J, Bachrati CZ, Hickson ID, Brown GW. BLM and RMI1 alleviate RPA inhibition of TopoIIIα decatenase activity. Plos One. 7: e41208. PMID 22911760 DOI: 10.1371/Journal.Pone.0041208 |
0.586 |
|
| 2012 |
Tkach JM, Yimit A, Lee AY, Riffle M, Costanzo M, Jaschob D, Hendry JA, Ou J, Moffat J, Boone C, Davis TN, Nislow C, Brown GW. Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nature Cell Biology. 14: 966-76. PMID 22842922 DOI: 10.1038/Ncb2549 |
0.543 |
|
| 2012 |
Cheng E, Vaisica JA, Ou J, Baryshnikova A, Lu Y, Roth FP, Brown GW. Genome rearrangements caused by depletion of essential DNA replication proteins in Saccharomyces cerevisiae. Genetics. 192: 147-60. PMID 22673806 DOI: 10.1534/Genetics.112.141051 |
0.808 |
|
| 2012 |
Yang J, O'Donnell L, Durocher D, Brown GW. RMI1 promotes DNA replication fork progression and recovery from replication fork stress. Molecular and Cellular Biology. 32: 3054-64. PMID 22645306 DOI: 10.1128/Mcb.00255-12 |
0.708 |
|
| 2012 |
Davidson MB, Katou Y, Keszthelyi A, Sing TL, Xia T, Ou J, Vaisica JA, Thevakumaran N, Marjavaara L, Myers CL, Chabes A, Shirahige K, Brown GW. Endogenous DNA replication stress results in expansion of dNTP pools and a mutator phenotype. The Embo Journal. 31: 895-907. PMID 22234187 DOI: 10.1038/Emboj.2011.485 |
0.79 |
|
| 2011 |
Bendaha H, Yu L, Touzani R, Souane R, Giaever G, Nislow C, Boone C, El Kadiri S, Brown GW, Bellaoui M. New azole antifungal agents with novel modes of action: synthesis and biological studies of new tridentate ligands based on pyrazole and triazole. European Journal of Medicinal Chemistry. 46: 4117-24. PMID 21723647 DOI: 10.1016/J.Ejmech.2011.06.012 |
0.365 |
|
| 2011 |
Bellay J, Atluri G, Sing TL, Toufighi K, Costanzo M, Ribeiro PS, Pandey G, Baller J, VanderSluis B, Michaut M, Han S, Kim P, Brown GW, Andrews BJ, Boone C, et al. Putting genetic interactions in context through a global modular decomposition. Genome Research. 21: 1375-87. PMID 21715556 DOI: 10.1101/Gr.117176.110 |
0.366 |
|
| 2011 |
Vaisica JA, Baryshnikova A, Costanzo M, Boone C, Brown GW. Mms1 and Mms22 stabilize the replisome during replication stress. Molecular Biology of the Cell. 22: 2396-408. PMID 21593207 DOI: 10.1091/Mbc.E10-10-0848 |
0.795 |
|
| 2011 |
Qaddouri B, Guaadaoui A, Bellirou A, Hamal A, Melhaoui A, Brown GW, Bellaoui M. The Budding Yeast "Saccharomyces cerevisiae" as a Drug Discovery Tool to Identify Plant-Derived Natural Products with Anti-Proliferative Properties. Evidence-Based Complementary and Alternative Medicine : Ecam. 2011: 954140. PMID 19596744 DOI: 10.1093/Ecam/Nep069 |
0.333 |
|
| 2010 |
Baryshnikova A, Costanzo M, Kim Y, Ding H, Koh J, Toufighi K, Youn JY, Ou J, San Luis BJ, Bandyopadhyay S, Hibbs M, Hess D, Gingras AC, Bader GD, Troyanskaya OG, ... Brown GW, et al. Quantitative analysis of fitness and genetic interactions in yeast on a genome scale. Nature Methods. 7: 1017-24. PMID 21076421 DOI: 10.1038/Nmeth.1534 |
0.342 |
|
| 2010 |
O'Donnell L, Panier S, Wildenhain J, Tkach JM, Al-Hakim A, Landry MC, Escribano-Diaz C, Szilard RK, Young JT, Munro M, Canny MD, Kolas NK, Zhang W, Harding SM, Ylanko J, ... ... Brown GW, et al. The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombination. Molecular Cell. 40: 619-31. PMID 21055983 DOI: 10.1016/J.Molcel.2010.10.024 |
0.595 |
|
| 2010 |
Berbenetz NM, Nislow C, Brown GW. Diversity of eukaryotic DNA replication origins revealed by genome-wide analysis of chromatin structure. Plos Genetics. 6: e1001092. PMID 20824081 DOI: 10.1371/Journal.Pgen.1001092 |
0.517 |
|
| 2010 |
Yang J, Bachrati CZ, Ou J, Hickson ID, Brown GW. Human topoisomerase IIIalpha is a single-stranded DNA decatenase that is stimulated by BLM and RMI1. The Journal of Biological Chemistry. 285: 21426-36. PMID 20445207 DOI: 10.1074/Jbc.M110.123216 |
0.648 |
|
| 2009 |
Dion B, Brown GW. Comparative genome hybridization on tiling microarrays to detect aneuploidies in yeast. Methods in Molecular Biology (Clifton, N.J.). 548: 1-18. PMID 19521816 DOI: 10.1007/978-1-59745-540-4_1 |
0.362 |
|
| 2009 |
Davidson MB, Brown GW. Dissecting the DNA damage response using functional genomics approaches in S. cerevisiae. Dna Repair. 8: 1110-7. PMID 19464964 DOI: 10.1016/J.Dnarep.2009.03.010 |
0.551 |
|
| 2008 |
Yu L, Lopez A, Anaflous A, El Bali B, Hamal A, Ericson E, Heisler LE, McQuibban A, Giaever G, Nislow C, Boone C, Brown GW, Bellaoui M. Chemical-genetic profiling of imidazo[1,2-a]pyridines and -pyrimidines reveals target pathways conserved between yeast and human cells. Plos Genetics. 4: e1000284. PMID 19043571 DOI: 10.1371/Journal.Pgen.1000284 |
0.427 |
|
| 2008 |
Nagai S, Dubrana K, Tsai-Pflugfelder M, Davidson MB, Roberts TM, Brown GW, Varela E, Hediger F, Gasser SM, Krogan NJ. Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase. Science (New York, N.Y.). 322: 597-602. PMID 18948542 DOI: 10.1126/Science.1162790 |
0.525 |
|
| 2008 |
Xu D, Guo R, Sobeck A, Bachrati CZ, Yang J, Enomoto T, Brown GW, Hoatlin ME, Hickson ID, Wang W. RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability. Genes & Development. 22: 2843-55. PMID 18923082 DOI: 10.1101/Gad.1708608 |
0.64 |
|
| 2008 |
Davidson MB, Brown GW. The N- and C-termini of Elg1 contribute to the maintenance of genome stability. Dna Repair. 7: 1221-32. PMID 18482875 DOI: 10.1016/J.Dnarep.2008.04.001 |
0.516 |
|
| 2008 |
Duro E, Vaisica JA, Brown GW, Rouse J. Budding yeast Mms22 and Mms1 regulate homologous recombination induced by replisome blockage. Dna Repair. 7: 811-8. PMID 18321796 DOI: 10.1016/J.Dnarep.2008.01.007 |
0.772 |
|
| 2008 |
Roberts TM, Zaidi IW, Vaisica JA, Peter M, Brown GW. Regulation of rtt107 recruitment to stalled DNA replication forks by the cullin rtt101 and the rtt109 acetyltransferase. Molecular Biology of the Cell. 19: 171-80. PMID 17978089 DOI: 10.1091/Mbc.E07-09-0961 |
0.805 |
|
| 2007 |
Xu H, Boone C, Brown GW. Genetic dissection of parallel sister-chromatid cohesion pathways. Genetics. 176: 1417-29. PMID 17483413 DOI: 10.1534/Genetics.107.072876 |
0.436 |
|
| 2007 |
Collins SR, Miller KM, Maas NL, Roguev A, Fillingham J, Chu CS, Schuldiner M, Gebbia M, Recht J, Shales M, Ding H, Xu H, Han J, Ingvarsdottir K, Cheng B, ... ... Brown GW, et al. Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature. 446: 806-10. PMID 17314980 DOI: 10.1038/Nature05649 |
0.463 |
|
| 2006 |
Yu L, Peña Castillo L, Mnaimneh S, Hughes TR, Brown GW. A survey of essential gene function in the yeast cell division cycle. Molecular Biology of the Cell. 17: 4736-47. PMID 16943325 DOI: 10.1091/Mbc.E06-04-0368 |
0.539 |
|
| 2006 |
Chang M, Parsons AB, Sheikh BH, Boone C, Brown GW. Genomic approaches for identifying DNA damage response pathways in S. cerevisiae. Methods in Enzymology. 409: 213-35. PMID 16793404 DOI: 10.1016/S0076-6879(05)09013-0 |
0.548 |
|
| 2006 |
Wu L, Bachrati CZ, Ou J, Xu C, Yin J, Chang M, Wang W, Li L, Brown GW, Hickson ID. BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates. Proceedings of the National Academy of Sciences of the United States of America. 103: 4068-73. PMID 16537486 DOI: 10.1073/Pnas.0508295103 |
0.456 |
|
| 2006 |
Zhang C, Roberts TM, Yang J, Desai R, Brown GW. Suppression of genomic instability by SLX5 and SLX8 in Saccharomyces cerevisiae. Dna Repair. 5: 336-46. PMID 16325482 DOI: 10.1016/J.Dnarep.2005.10.010 |
0.724 |
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| 2006 |
Roberts TM, Kobor MS, Bastin-Shanower SA, Ii M, Horte SA, Gin JW, Emili A, Rine J, Brill SJ, Brown GW. Slx4 regulates DNA damage checkpoint-dependent phosphorylation of the BRCT domain protein Rtt107/Esc4. Molecular Biology of the Cell. 17: 539-48. PMID 16267268 DOI: 10.1091/Mbc.E05-08-0785 |
0.56 |
|
| 2005 |
Davierwala AP, Haynes J, Li Z, Brost RL, Robinson MD, Yu L, Mnaimneh S, Ding H, Zhu H, Chen Y, Cheng X, Brown GW, Boone C, Andrews BJ, Hughes TR. The synthetic genetic interaction spectrum of essential genes. Nature Genetics. 37: 1147-52. PMID 16155567 DOI: 10.1038/Ng1640 |
0.368 |
|
| 2005 |
Chang M, Bellaoui M, Zhang C, Desai R, Morozov P, Delgado-Cruzata L, Rothstein R, Freyer GA, Boone C, Brown GW. RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex. The Embo Journal. 24: 2024-33. PMID 15889139 DOI: 10.1038/Sj.Emboj.7600684 |
0.594 |
|
| 2004 |
Suter B, Tong A, Chang M, Yu L, Brown GW, Boone C, Rine J. The origin recognition complex links replication, sister chromatid cohesion and transcriptional silencing in Saccharomyces cerevisiae. Genetics. 167: 579-91. PMID 15238513 DOI: 10.1534/Genetics.103.024851 |
0.562 |
|
| 2004 |
Tong AH, Lesage G, Bader GD, Ding H, Xu H, Xin X, Young J, Berriz GF, Brost RL, Chang M, Chen Y, Cheng X, Chua G, Friesen H, Goldberg DS, ... ... Brown GW, et al. Global mapping of the yeast genetic interaction network. Science (New York, N.Y.). 303: 808-13. PMID 14764870 DOI: 10.1126/Science.1091317 |
0.333 |
|
| 2004 |
Mayer ML, Pot I, Chang M, Xu H, Aneliunas V, Kwok T, Newitt R, Aebersold R, Boone C, Brown GW, Hieter P. Identification of protein complexes required for efficient sister chromatid cohesion. Molecular Biology of the Cell. 15: 1736-45. PMID 14742714 DOI: 10.1091/Mbc.E03-08-0619 |
0.418 |
|
| 2004 |
Parsons AB, Brost RL, Ding H, Li Z, Zhang C, Sheikh B, Brown GW, Kane PM, Hughes TR, Boone C. Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways. Nature Biotechnology. 22: 62-9. PMID 14661025 DOI: 10.1038/Nbt919 |
0.321 |
|
| 2003 |
Duncker BP, Brown GW. Cdc7 kinases (DDKs) and checkpoint responses: lessons from two yeasts. Mutation Research. 532: 21-7. PMID 14643426 DOI: 10.1016/J.Mrfmmm.2003.08.007 |
0.495 |
|
| 2003 |
Bellaoui M, Chang M, Ou J, Xu H, Boone C, Brown GW. Elg1 forms an alternative RFC complex important for DNA replication and genome integrity. The Embo Journal. 22: 4304-13. PMID 12912927 DOI: 10.1093/Emboj/Cdg406 |
0.61 |
|
| 2002 |
Chang M, Bellaoui M, Boone C, Brown GW. A genome-wide screen for methyl methanesulfonate-sensitive mutants reveals genes required for S phase progression in the presence of DNA damage. Proceedings of the National Academy of Sciences of the United States of America. 99: 16934-9. PMID 12482937 DOI: 10.1073/Pnas.262669299 |
0.516 |
|
| 2002 |
Fung AD, Ou J, Bueler S, Brown GW. A conserved domain of Schizosaccharomyces pombe dfp1(+) is uniquely required for chromosome stability following alkylation damage during S phase. Molecular and Cellular Biology. 22: 4477-90. PMID 12052858 DOI: 10.1128/Mcb.22.13.4477-4490.2002 |
0.521 |
|
| 2000 |
Snaith HA, Brown GW, Forsburg SL. Schizosaccharomyces pombe Hsk1p is a potential cds1p target required for genome integrity. Molecular and Cellular Biology. 20: 7922-32. PMID 11027263 DOI: 10.1128/Mcb.20.21.7922-7932.2000 |
0.543 |
|
| 2000 |
Kelly TJ, Brown GW. Regulation of chromosome replication. Annual Review of Biochemistry. 69: 829-80. PMID 10966477 DOI: 10.1146/Annurev.Biochem.69.1.829 |
0.695 |
|
| 1999 |
Brown GW, Kelly TJ. Cell cycle regulation of Dfp1, an activator of the Hsk1 protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 96: 8443-8. PMID 10411894 DOI: 10.1073/Pnas.96.15.8443 |
0.635 |
|
| 1998 |
Brown GW, Kelly TJ. Purification of Hsk1, a minichromosome maintenance protein kinase from fission yeast. The Journal of Biological Chemistry. 273: 22083-90. PMID 9705352 DOI: 10.1074/Jbc.273.34.22083 |
0.613 |
|
| 1997 |
Jallepalli PV, Brown GW, Muzi-Falconi M, Tien D, Kelly TJ. Regulation of the replication initiator protein p65cdc18 by CDK phosphorylation. Genes & Development. 11: 2767-79. PMID 9353247 DOI: 10.1101/Gad.11.21.2767 |
0.63 |
|
| 1997 |
Brown GW, Jallepalli PV, Huneycutt BJ, Kelly TJ. Interaction of the S phase regulator cdc18 with cyclin-dependent kinase in fission yeast. Proceedings of the National Academy of Sciences of the United States of America. 94: 6142-7. PMID 9177184 DOI: 10.1073/Pnas.94.12.6142 |
0.583 |
|
| 1996 |
Muzi-Falconi M, Brown GW, Kelly TJ. Controlling initiation during the cell cycle. DNA replication. Current Biology : Cb. 6: 229-33. PMID 8805233 DOI: 10.1016/S0960-9822(02)00464-5 |
0.662 |
|
| 1996 |
Muzi Falconi M, Brown GW, Kelly TJ. cdc18+ regulates initiation of DNA replication in Schizosaccharomyces pombe. Proceedings of the National Academy of Sciences of the United States of America. 93: 1566-70. PMID 8643672 DOI: 10.1073/Pnas.93.4.1566 |
0.691 |
|
| 1994 |
Brown GW, Hines JC, Fisher P, Ray DS. Isolation of the genes encoding the 51-kilodalton and 28-kilodalton subunits of Crithidia fasciculata replication protein A Molecular and Biochemical Parasitology. 63: 135-142. PMID 8183313 DOI: 10.1016/0166-6851(94)90016-7 |
0.639 |
|
| 1994 |
Pasion SG, Brown GW, Brown LM, Ray DS. Periodic expression of nuclear and mitochondrial DNA replication genes during the trypanosomatid cell cycle. Journal of Cell Science. 107: 3515-20. PMID 7706402 |
0.399 |
|
| 1993 |
Brown GW, Melendy T, Ray DS. Replication protein A from the trypanosomatid Crithidia fasciculata is inactive in the primosome assembly step of SV40 DNA replication Molecular and Biochemical Parasitology. 59: 323-325. PMID 8393527 DOI: 10.1016/0166-6851(93)90230-U |
0.721 |
|
| 1992 |
Brown GW, Ray DS. Purification and characterization of DNA ligase I from the trypanosomatid Crithidia fasciculata Nucleic Acids Research. 20: 3905-3910. PMID 1508676 DOI: 10.1093/Nar/20.15.3905 |
0.691 |
|
| 1992 |
Brown GW, Melendy TE, Ray DS. Conservation of structure and function of DNA replication protein A in the trypanosomatid Crithidia fasciculata. Proceedings of the National Academy of Sciences of the United States of America. 89: 10227-31. PMID 1332038 DOI: 10.1073/Pnas.89.21.10227 |
0.731 |
|
| 1991 |
Yeung DE, Brown GW, Tam P, Russnak RH, Wilson G, Clark-Lewis I, Astell CR. Monoclonal antibodies to the major nonstructural nuclear protein of minute virus of mice Virology. 181: 35-45. PMID 1825254 DOI: 10.1016/0042-6822(91)90467-P |
0.318 |
|
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