Mary M. Maleckar, Ph.D. - Publications

Affiliations: 
2008 Johns Hopkins University, Baltimore, MD 
Area:
Biomedical Engineering, Medical Biophysics

29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Tveito A, Jæger KH, Maleckar MM, Giles WR, Wall S. Computational translation of drug effects from animal experiments to human ventricular myocytes. Scientific Reports. 10: 10537. PMID 32601303 DOI: 10.1038/S41598-020-66910-0  0.32
2019 Jæger KH, Charwat V, Charrez B, Finsberg H, Maleckar MM, Wall S, Healy KE, Tveito A. Improved Computational Identification of Drug Response Using Optical Measurements of Human Stem Cell Derived Cardiomyocytes in Microphysiological Systems. Frontiers in Pharmacology. 10: 1648. PMID 32116671 DOI: 10.3389/Fphar.2019.01648  0.331
2018 Maleckar MM, Clark RB, Votta B, Giles WR. The Resting Potential and K Currents in Primary Human Articular Chondrocytes. Frontiers in Physiology. 9: 974. PMID 30233381 DOI: 10.3389/Fphys.2018.00974  0.335
2018 Morotti S, Ellinwood N, Ni H, Koivumäki JT, Maleckar MM, Heijman J, Dobrev D, Grandi E. Effects of Modulation of Small-Conductance Calcium-Activated Potassium Current on Atrial Electrophysiology and Arrhythmogenesis: A Population-Based Computational Study Biophysical Journal. 114: 473a. DOI: 10.1016/J.Bpj.2017.11.2604  0.303
2017 Vagos MR, Arevalo H, de Oliveira BL, Sundnes J, Maleckar MM. A computational framework for testing arrhythmia marker sensitivities to model parameters in functionally calibrated populations of atrial cells. Chaos (Woodbury, N.Y.). 27: 093941. PMID 28964122 DOI: 10.1063/1.4999476  0.352
2017 Kallhovd S, Maleckar MM, Rognes ME. Inverse estimation of cardiac activation times via gradient-based optimisation. International Journal For Numerical Methods in Biomedical Engineering. PMID 28744962 DOI: 10.1002/Cnm.2919  0.389
2017 Belardinelli L, Maleckar MM, Giles WR. Ventricular Microanatomy, Arrhythmias, and the Electrochemical Driving Force for Na(+): Is There a Need for Flipped Learning? Circulation. Arrhythmia and Electrophysiology. 10: e004955. PMID 28213509 DOI: 10.1161/Circep.117.004955  0.369
2017 Lines GT, de Oliveira BL, Skavhaug O, Maleckar MM. Simple T-Wave Metrics May Better Predict Early Ischemia as Compared to ST Segment. Ieee Transactions On Bio-Medical Engineering. 64: 1305-1309. PMID 27576235 DOI: 10.1109/Tbme.2016.2600198  0.337
2016 Skibsbye L, Jespersen T, Christ T, Maleckar MM, van den Brink J, Tavi P, Koivumäki JT. Refractoriness in human atria: Time and voltage dependence of sodium channel availability. Journal of Molecular and Cellular Cardiology. PMID 27773652 DOI: 10.1016/J.Yjmcc.2016.10.009  0.352
2016 Grandi E, Maleckar MM. Anti-arrhythmic strategies for atrial fibrillation: The role of computational modeling in discovery, development, and optimization. Pharmacology & Therapeutics. PMID 27612549 DOI: 10.1016/J.Pharmthera.2016.09.012  0.352
2016 Morotti S, Koivumäki JT, Maleckar MM, Chiamvimonvat N, Grandi E. Small-Conductance Ca2+-Activated K+ Current in Atrial Fibrillation: Both Friend and FOE Biophysical Journal. 110: 274a. DOI: 10.1016/J.Bpj.2015.11.1487  0.328
2014 Maleckar MM, Lines GT, Koivumäki JT, Cordeiro JM, Calloe K. NS5806 partially restores action potential duration but fails to ameliorate calcium transient dysfunction in a computational model of canine heart failure. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. 16: iv46-iv55. PMID 25362170 DOI: 10.1093/Europace/Euu252  0.318
2014 Koivumäki JT, Seemann G, Maleckar MM, Tavi P. In silico screening of the key cellular remodeling targets in chronic atrial fibrillation. Plos Computational Biology. 10: e1003620. PMID 24853123 DOI: 10.1371/Journal.Pcbi.1003620  0.361
2013 Li P, Lines GT, Maleckar MM, Tveito A. Mathematical models of cardiac pacemaking function Frontiers in Physics. 1. DOI: 10.3389/Fphy.2013.00020  0.371
2012 Rose RA, Belke DD, Maleckar MM, Giles WR. Ca(2+) entry through TRP-C channels regulates fibroblast biology in chronic atrial fibrillation. Circulation. 126: 2039-41. PMID 23091082 DOI: 10.1161/Circulationaha.112.138065  0.372
2012 Tveito A, Lines GT, Edwards AG, Maleckar MM, Michailova A, Hake J, McCulloch A. Slow Calcium-Depolarization-Calcium waves may initiate fast local depolarization waves in ventricular tissue Progress in Biophysics and Molecular Biology. 110: 295-304. PMID 22841534 DOI: 10.1016/J.Pbiomolbio.2012.07.005  0.31
2012 Tveito A, Lines GT, Maleckar MM. Note on a possible proarrhythmic property of antiarrhythmic drugs aimed at improving gap-junction coupling. Biophysical Journal. 102: 231-7. PMID 22339859 DOI: 10.1016/J.Bpj.2011.11.4015  0.331
2011 Niederer SA, Kerfoot E, Benson AP, Bernabeu MO, Bernus O, Bradley C, Cherry EM, Clayton R, Fenton FH, Garny A, Heidenreich E, Land S, Maleckar M, Pathmanathan P, Plank G, et al. Verification of cardiac tissue electrophysiology simulators using an N-version benchmark. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 369: 4331-51. PMID 21969679 DOI: 10.1098/Rsta.2011.0139  0.306
2011 McDowell KS, Arevalo HJ, Maleckar MM, Trayanova NA. Susceptibility to arrhythmia in the infarcted heart depends on myofibroblast density. Biophysical Journal. 101: 1307-15. PMID 21943411 DOI: 10.1016/J.Bpj.2011.08.009  0.527
2011 Tveito A, Lines G, Skavhaug O, Maleckar MM. Unstable eigenmodes are possible drivers for cardiac arrhythmias. Journal of the Royal Society, Interface / the Royal Society. 8: 1212-6. PMID 21571942 DOI: 10.1098/Rsif.2011.0152  0.305
2011 Tveito A, Lines G, Artebrant R, Skavhaug O, Maleckar MM. Existence of excitation waves for a collection of cardiomyocytes electrically coupled to fibroblasts. Mathematical Biosciences. 230: 79-86. PMID 21296091 DOI: 10.1016/J.Mbs.2011.01.004  0.365
2009 Maleckar MM, Greenstein JL, Giles WR, Trayanova NA. Electrotonic coupling between human atrial myocytes and fibroblasts alters myocyte excitability and repolarization. Biophysical Journal. 97: 2179-90. PMID 19843450 DOI: 10.1016/J.Bpj.2009.07.054  0.543
2009 Maleckar MM, Greenstein JL, Giles WR, Trayanova NA. K+ current changes account for the rate dependence of the action potential in the human atrial myocyte. American Journal of Physiology. Heart and Circulatory Physiology. 297: H1398-410. PMID 19633207 DOI: 10.1152/Ajpheart.00411.2009  0.52
2008 Maleckar MM, Greenstein JL, Trayanova NA, Giles WR. Mathematical simulations of ligand-gated and cell-type specific effects on the action potential of human atrium. Progress in Biophysics and Molecular Biology. 98: 161-70. PMID 19186188 DOI: 10.1016/J.Pbiomolbio.2009.01.010  0.547
2008 Maleckar MM, Woods MC, Sidorov VY, Holcomb MR, Mashburn DN, Wikswo JP, Trayanova NA. Polarity reversal lowers activation time during diastolic field stimulation of the rabbit ventricles: insights into mechanisms. American Journal of Physiology. Heart and Circulatory Physiology. 295: H1626-33. PMID 18708441 DOI: 10.1152/Ajpheart.00706.2008  0.519
2006 Gurev V, Maleckar MM, Trayanova NA. Cardiac defibrillation and the role of mechanoelectric feedback in postshock arrhythmogenesis. Annals of the New York Academy of Sciences. 1080: 320-33. PMID 17132792 DOI: 10.1196/Annals.1380.024  0.537
2006 Bourn DW, Maleckar MM, Rodriguez B, Trayanova NA. Mechanistic enquiry into the effect of increased pacing rate on the upper limit of vulnerability. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 364: 1333-48. PMID 16766348 DOI: 10.1098/Rsta.2006.1775  0.662
2006 Maleckar MM, Blake RC, Trayanova NA. P3-27 Heart Rhythm. 3: S187. DOI: 10.1016/J.Hrthm.2006.02.559  0.397
2005 Maleckar MM, Bourn DW, Rodriguez B, Trayanova NA. Mechanistic insight into the increase in the upper limit of vulnerability for rapid pacing Heart Rhythm. 2: S219. DOI: 10.1016/J.Hrthm.2005.02.684  0.644
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