| Year |
Citation |
Score |
| 2024 |
Allyn BM, Hayer KE, Oyeniran C, Nganga V, Lee K, Mishra B, Sacan A, Oltz EM, Bassing CH. Locus folding mechanisms determine modes of antigen receptor gene assembly. The Journal of Experimental Medicine. 221. PMID 38189780 DOI: 10.1084/jem.20230985 |
0.324 |
|
| 2023 |
Culberson EJ, Shields KC, Glynn RA, Allyn BM, Hayer KE, Bassing CH. The Cyclin D3 Protein Enforces Monogenic TCRβ Expression by Mediating TCRβ Protein-Signaled Feedback Inhibition of Vβ Recombination. Journal of Immunology (Baltimore, Md. : 1950). PMID 38117277 DOI: 10.4049/jimmunol.2300623 |
0.37 |
|
| 2022 |
Burn TN, Miot C, Gordon SM, Culberson EJ, Diamond T, Kreiger PA, Hayer KE, Bhattacharyya A, Jones JM, Bassing CH, Behrens EM. The RAG1 Ubiquitin Ligase Domain Stimulates Recombination of TCRβ and TCRα Genes and Influences Development of αβ T Cell Lineages. Journal of Immunology (Baltimore, Md. : 1950). PMID 35948399 DOI: 10.4049/jimmunol.2001441 |
0.342 |
|
| 2022 |
Culberson EJ, Bassing CH. Monogenic TCRβ Assembly and Expression Are Paramount for Uniform Antigen Receptor Specificity of Individual αβ T Lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 209: 93-98. PMID 35697383 DOI: 10.4049/jimmunol.2200176 |
0.34 |
|
| 2022 |
Wu GS, Culberson EJ, Allyn BM, Bassing CH. Poor-Quality Vβ Recombination Signal Sequences and the DNA Damage Response ATM Kinase Collaborate to Establish TCRβ Gene Repertoire and Allelic Exclusion. Journal of Immunology (Baltimore, Md. : 1950). 208: 2583-2592. PMID 35534211 DOI: 10.4049/jimmunol.2100489 |
0.367 |
|
| 2021 |
Glynn RA, Bassing CH. Nemo-Dependent, ATM-Mediated Signals from RAG DNA Breaks at Feedback Inhibit Recombination to Enforce Igκ Allelic Exclusion. Journal of Immunology (Baltimore, Md. : 1950). 208: 371-383. PMID 34965965 DOI: 10.4049/jimmunol.2100696 |
0.38 |
|
| 2021 |
Beilinson HA, Glynn RA, Yadavalli AD, Xiao J, Corbett E, Saribasak H, Arya R, Miot C, Bhattacharyya A, Jones JM, Pongubala JMR, Bassing CH, Schatz DG. The RAG1 N-terminal region regulates the efficiency and pathways of synapsis for V(D)J recombination. The Journal of Experimental Medicine. 218. PMID 34402853 DOI: 10.1084/jem.20210250 |
0.329 |
|
| 2020 |
Wu GS, Bassing CH. Inefficient V(D)J recombination underlies monogenic T cell receptor β expression. Proceedings of the National Academy of Sciences of the United States of America. PMID 32690689 DOI: 10.1073/Pnas.2010077117 |
0.477 |
|
| 2020 |
Collins PL, Purman C, Porter SI, Nganga V, Saini A, Hayer KE, Gurewitz GL, Sleckman BP, Bednarski JJ, Bassing CH, Oltz EM. DNA double-strand breaks induce H2Ax phosphorylation domains in a contact-dependent manner. Nature Communications. 11: 3158. PMID 32572033 DOI: 10.1038/S41467-020-16926-X |
0.382 |
|
| 2020 |
Wu GS, Yang-Iott KS, Klink MA, Hayer KE, Lee KD, Bassing CH. Poor quality Vβ recombination signal sequences stochastically enforce TCRβ allelic exclusion. The Journal of Experimental Medicine. 217. PMID 32526772 DOI: 10.1084/Jem.20200412 |
0.417 |
|
| 2020 |
Allyn BM, Lee KD, Bassing CH. Genome Topology Control of Antigen Receptor Gene Assembly. Journal of Immunology (Baltimore, Md. : 1950). 204: 2617-2626. PMID 32366683 DOI: 10.4049/Jimmunol.1901356 |
0.419 |
|
| 2019 |
Lee KD, Bassing CH. Two Successive Inversional Vβ Rearrangements on a Single Allele Can Contribute to the TCRβ Repertoire. Journal of Immunology (Baltimore, Md. : 1950). PMID 31740488 DOI: 10.4049/Jimmunol.1901105 |
0.435 |
|
| 2019 |
Glynn RA, Bassing CH. From RAG2 to T Cell Riches and Future Fortunes. Journal of Immunology (Baltimore, Md. : 1950). 202: 1315-1316. PMID 30782849 DOI: 10.4049/Jimmunol.1900010 |
0.338 |
|
| 2018 |
Wu GS, Bassing CH. Flip the switch: BTG2-PRMT1 protein complexes antagonize pre-B-cell proliferation to promote B-cell development. Cellular & Molecular Immunology. PMID 29429994 DOI: 10.1038/Cmi.2017.156 |
0.349 |
|
| 2017 |
Wu GS, Bassing CH. The ESCRT protein CHMP5 escorts αβ T cells through positive selection. Cellular & Molecular Immunology. PMID 28990583 DOI: 10.1038/Cmi.2017.101 |
0.321 |
|
| 2017 |
Arya R, Bassing CH. V(D)J Recombination Exploits DNA Damage Responses to Promote Immunity. Trends in Genetics : Tig. PMID 28532625 DOI: 10.1016/J.Tig.2017.04.006 |
0.453 |
|
| 2017 |
Fisher MR, Rivera-Reyes A, Bloch NB, Schatz DG, Bassing CH. Immature Lymphocytes Inhibit Rag1 and Rag2 Transcription and V(D)J Recombination in Response to DNA Double-Strand Breaks. Journal of Immunology (Baltimore, Md. : 1950). PMID 28213501 DOI: 10.4049/Jimmunol.1601639 |
0.517 |
|
| 2016 |
Rivera-Reyes A, Hayer KE, Bassing CH. Genomic Alterations of Non-Coding Regions Underlie Human Cancer: Lessons from T-ALL. Trends in Molecular Medicine. 22: 1035-1046. PMID 28240214 DOI: 10.1016/J.Molmed.2016.10.004 |
0.357 |
|
| 2016 |
DeMicco A, Reich T, Arya R, Rivera-Reyes A, Fisher MR, Bassing CH. Lymphocyte Lineage-Specific and Developmental Stage Specific Mechanisms Suppress Cyclin D3 Expression in Response to DNA Double Strand Breaks. Cell Cycle (Georgetown, Tex.). 0. PMID 27327568 DOI: 10.1080/15384101.2016.1198861 |
0.425 |
|
| 2016 |
Fidanza M, Seif AE, DeMicco A, Rolf N, Jo S, Yin B, Li Y, Barrett DM, Duque-Afonso J, Cleary ML, Bassing CH, Grupp SA, Reid GS. Inhibition of precursor B cell malignancy progression by toll-like receptor ligand-induced immune responses. Leukemia. PMID 27220664 DOI: 10.1038/Leu.2016.152 |
0.574 |
|
| 2016 |
Bednarski JJ, Pandey R, Schulte E, White LS, Chen BR, Sandoval GJ, Kohyama M, Haldar M, Nickless A, Trott A, Cheng G, Murphy KM, Bassing CH, Payton JE, Sleckman BP. RAG-mediated DNA double-strand breaks activate a cell type-specific checkpoint to inhibit pre-B cell receptor signals. The Journal of Experimental Medicine. PMID 26834154 DOI: 10.1084/Jem.20151048 |
0.47 |
|
| 2016 |
Rupp LJ, Chen L, Krangel MS, Bassing CH. Molecular Analysis of Mouse T Cell Receptor α and β Gene Rearrangements. Methods in Molecular Biology (Clifton, N.J.). 1323: 179-202. PMID 26294409 DOI: 10.1007/978-1-4939-2809-5_16 |
0.636 |
|
| 2016 |
Rupp LJ, Chen L, Krangel MS, Bassing CH. Molecular Analysis of Mouse T Cell Receptor α and β Gene Rearrangements Methods in Molecular Biology. 1323: 179-202. DOI: 10.1007/978-1-4939-2809-5_16 |
0.578 |
|
| 2015 |
Balestrini A, Nicolas L, Yang-Lott K, Guryanova OA, Levine RL, Bassing CH, Chaudhuri J, Petrini JH. Defining ATM-independent Functions of the Mre11 Complex with a Novel Mouse Model. Molecular Cancer Research : McR. PMID 26538284 DOI: 10.1158/1541-7786.Mcr-15-0281 |
0.396 |
|
| 2015 |
Majumder K, Bassing CH, Oltz EM. Regulation of Tcrb Gene Assembly by Genetic, Epigenetic, and Topological Mechanisms. Advances in Immunology. 128: 273-306. PMID 26477369 DOI: 10.1016/Bs.Ai.2015.07.001 |
0.474 |
|
| 2015 |
Fisher MR, Bassing CH. To κ(+) B or not to κ(+) B. Nature Immunology. 16: 1007-9. PMID 26382861 DOI: 10.1038/Ni.3277 |
0.4 |
|
| 2015 |
DeMicco A, Naradikian MS, Sindhava VJ, Yoon JH, Gorospe M, Wertheim GB, Cancro MP, Bassing CH. B Cell-Intrinsic Expression of the HuR RNA-Binding Protein Is Required for the T Cell-Dependent Immune Response In Vivo. Journal of Immunology (Baltimore, Md. : 1950). PMID 26320247 DOI: 10.4049/Jimmunol.1500512 |
0.449 |
|
| 2015 |
Majumder K, Rupp LJ, Yang-Iott KS, Koues OI, Kyle KE, Bassing CH, Oltz EM. Domain-Specific and Stage-Intrinsic Changes in Tcrb Conformation during Thymocyte Development. Journal of Immunology (Baltimore, Md. : 1950). 195: 1262-72. PMID 26101321 DOI: 10.4049/Jimmunol.1500692 |
0.663 |
|
| 2015 |
Ehrlich LA, Yang-Iott K, DeMicco A, Bassing CH. Somatic inactivation of ATM in hematopoietic cells predisposes mice to cyclin D3 dependent T cell acute lymphoblastic leukemia. Cell Cycle (Georgetown, Tex.). 14: 388-98. PMID 25659036 DOI: 10.4161/15384101.2014.988020 |
0.432 |
|
| 2015 |
Majumder K, Koues OI, Chan EA, Kyle KE, Horowitz JE, Yang-Iott K, Bassing CH, Taniuchi I, Krangel MS, Oltz EM. Lineage-specific compaction of Tcrb requires a chromatin barrier to protect the function of a long-range tethering element. The Journal of Experimental Medicine. 212: 107-20. PMID 25512470 DOI: 10.1084/Jem.20141479 |
0.344 |
|
| 2014 |
Ehrlich LA, Yang-Iott K, Bassing CH. Tcrδ translocations that delete the Bcl11b haploinsufficient tumor suppressor gene promote atm-deficient T cell acute lymphoblastic leukemia. Cell Cycle (Georgetown, Tex.). 13: 3076-82. PMID 25486566 DOI: 10.4161/15384101.2014.949144 |
0.457 |
|
| 2014 |
Rupp LJ, Brady BL, Carpenter AC, De Obaldia ME, Bhandoola A, Bosselut R, Muljo SA, Bassing CH. The microRNA biogenesis machinery modulates lineage commitment during αβ T cell development. Journal of Immunology (Baltimore, Md. : 1950). 193: 4032-42. PMID 25217159 DOI: 10.4049/Jimmunol.1401359 |
0.755 |
|
| 2014 |
Steinel NC, Fisher MR, Yang-Iott KS, Bassing CH. The ataxia telangiectasia mutated and cyclin D3 proteins cooperate to help enforce TCRβ and IgH allelic exclusion. Journal of Immunology (Baltimore, Md. : 1950). 193: 2881-90. PMID 25127855 DOI: 10.4049/Jimmunol.1302201 |
0.782 |
|
| 2014 |
Horowitz JE, Bassing CH. Noncore RAG1 regions promote Vβ rearrangements and αβ T cell development by overcoming inherent inefficiency of Vβ recombination signal sequences. Journal of Immunology (Baltimore, Md. : 1950). 192: 1609-19. PMID 24415779 DOI: 10.4049/Jimmunol.1301599 |
0.416 |
|
| 2014 |
Vaites LP, Lian Z, Lee EK, Yin B, DeMicco A, Bassing CH, Diehl JA. ATM deficiency augments constitutively nuclear cyclin D1-driven genomic instability and lymphomagenesis. Oncogene. 33: 129-33. PMID 23318439 DOI: 10.1038/Onc.2012.577 |
0.651 |
|
| 2013 |
Sandoval GJ, Graham DB, Gmyrek GB, Akilesh HM, Fujikawa K, Sammut B, Bhattacharya D, Srivatsan S, Kim A, Shaw AS, Yang-Iott K, Bassing CH, Duncavage E, Xavier RJ, Swat W. Novel mechanism of tumor suppression by polarity gene discs large 1 (DLG1) revealed in a murine model of pediatric B-ALL. Cancer Immunology Research. 1: 426-37. PMID 24778134 DOI: 10.1158/2326-6066.Cir-13-0065 |
0.41 |
|
| 2013 |
Chan EA, Teng G, Corbett E, Choudhury KR, Bassing CH, Schatz DG, Krangel MS. Peripheral subnuclear positioning suppresses Tcrb recombination and segregates Tcrb alleles from RAG2. Proceedings of the National Academy of Sciences of the United States of America. 110: E4628-37. PMID 24218622 DOI: 10.1073/Pnas.1310846110 |
0.456 |
|
| 2013 |
DeMicco A, Yang-Iott K, Bassing CH. Somatic inactivation of Tp53 in hematopoietic stem cells or thymocytes predisposes mice to thymic lymphomas with clonal translocations. Cell Cycle (Georgetown, Tex.). 12: 3307-16. PMID 24036547 DOI: 10.4161/Cc.26299 |
0.473 |
|
| 2013 |
Fusello A, Horowitz J, Yang-Iott K, Brady BL, Yin B, Rowh MA, Rappaport E, Bassing CH. Histone H2AX suppresses translocations in lymphomas of Eμ-c-Myc transgenic mice that contain a germline amplicon of tumor-promoting genes. Cell Cycle (Georgetown, Tex.). 12: 2867-75. PMID 23966158 DOI: 10.4161/Cc.25922 |
0.778 |
|
| 2013 |
Lee BS, Gapud EJ, Zhang S, Dorsett Y, Bredemeyer A, George R, Callen E, Daniel JA, Osipovich O, Oltz EM, Bassing CH, Nussenzweig A, Lees-Miller S, Hammel M, Chen BP, et al. Functional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombination. Molecular and Cellular Biology. 33: 3568-79. PMID 23836881 DOI: 10.1128/Mcb.00308-13 |
0.362 |
|
| 2013 |
Brady BL, Rupp LJ, Bassing CH. Requirement for dicer in survival of proliferating thymocytes experiencing DNA double-strand breaks. Journal of Immunology (Baltimore, Md. : 1950). 190: 3256-66. PMID 23427252 DOI: 10.4049/Jimmunol.1200957 |
0.765 |
|
| 2013 |
Steinel NC, Lee BS, Tubbs AT, Bednarski JJ, Schulte E, Yang-Iott KS, Schatz DG, Sleckman BP, Bassing CH. The ataxia telangiectasia mutated kinase controls Igκ allelic exclusion by inhibiting secondary Vκ-to-Jκ rearrangements. The Journal of Experimental Medicine. 210: 233-9. PMID 23382544 DOI: 10.1084/Jem.20121605 |
0.768 |
|
| 2013 |
Gostissa M, Bianco JM, Malkin DJ, Kutok JL, Rodig SJ, Morse HC, Bassing CH, Alt FW. Conditional inactivation of p53 in mature B cells promotes generation of nongerminal center-derived B-cell lymphomas. Proceedings of the National Academy of Sciences of the United States of America. 110: 2934-9. PMID 23382223 DOI: 10.1073/Pnas.1222570110 |
0.414 |
|
| 2012 |
Yin B, Lee BS, Yang-Iott KS, Sleckman BP, Bassing CH. Redundant and nonredundant functions of ATM and H2AX in αβ T-lineage lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 189: 1372-9. PMID 22730535 DOI: 10.4049/Jimmunol.1200829 |
0.674 |
|
| 2012 |
Ehrlich LA, Yang-Iott KS, DeMicco A, Bassing CH. Deletion of Atm in the Hematopoetic Stem Cell As a Mouse Model for Human T Cell Acute Lymphoblastic Leukemia/Lymphoma. Blood. 120: 2418-2418. DOI: 10.1182/Blood.V120.21.2418.2418 |
0.43 |
|
| 2011 |
Brady BL, Bassing CH. Differential regulation of proximal and distal Vbeta segments upstream of a functional VDJbeta1 rearrangement upon beta-selection. Journal of Immunology (Baltimore, Md. : 1950). 187: 3277-85. PMID 21844384 DOI: 10.4049/Jimmunol.1101079 |
0.609 |
|
| 2011 |
Gapud EJ, Lee BS, Mahowald GK, Bassing CH, Sleckman BP. Repair of chromosomal RAG-mediated DNA breaks by mutant RAG proteins lacking phosphatidylinositol 3-like kinase consensus phosphorylation sites. Journal of Immunology (Baltimore, Md. : 1950). 187: 1826-34. PMID 21742970 DOI: 10.4049/Jimmunol.1101388 |
0.418 |
|
| 2011 |
Rowh MA, DeMicco A, Horowitz JE, Yin B, Yang-Iott KS, Fusello AM, Hobeika E, Reth M, Bassing CH. Tp53 deletion in B lineage cells predisposes mice to lymphomas with oncogenic translocations. Oncogene. 30: 4757-64. PMID 21625223 DOI: 10.1038/Onc.2011.191 |
0.796 |
|
| 2011 |
Sherman MH, Bassing CH, Teitell MA. Regulation of cell differentiation by the DNA damage response. Trends in Cell Biology. 21: 312-9. PMID 21354798 DOI: 10.1016/J.Tcb.2011.01.004 |
0.375 |
|
| 2011 |
Gapud EJ, Dorsett Y, Yin B, Callen E, Bredemeyer A, Mahowald GK, Omi KQ, Walker LM, Bednarski JJ, McKinnon PJ, Bassing CH, Nussenzweig A, Sleckman BP. Ataxia telangiectasia mutated (Atm) and DNA-PKcs kinases have overlapping activities during chromosomal signal joint formation. Proceedings of the National Academy of Sciences of the United States of America. 108: 2022-7. PMID 21245316 DOI: 10.1073/Pnas.1013295108 |
0.617 |
|
| 2011 |
Helmink BA, Tubbs AT, Dorsett Y, Bednarski JJ, Walker LM, Feng Z, Sharma GG, McKinnon PJ, Zhang J, Bassing CH, Sleckman BP. H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes. Nature. 469: 245-9. PMID 21160476 DOI: 10.1038/Nature09585 |
0.414 |
|
| 2011 |
Yin B, Yang-Iott KS, Chao LH, Bassing CH. Cellular context-dependent effects of H2ax and p53 deletion on the development of thymic lymphoma. Blood. 117: 175-85. PMID 20947684 DOI: 10.1182/Blood-2010-03-273045 |
0.612 |
|
| 2011 |
Helmink BA, Tubbs AT, Dorsett Y, Bednarski JJ, M.walker L, Feng Z, Sharma GG, McKinnon PJ, Zhang J, Bassing CH, Sleckman BP. H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes (Nature 469 (2010) (245-249)) Nature. 472: 247. DOI: 10.1038/Nature09942 |
0.321 |
|
| 2010 |
DeMicco A, Bassing CH. Deciphering the DNA damage histone code. Cell Cycle (Georgetown, Tex.). 9: 3845. PMID 20948284 DOI: 10.4161/Cc.9.19.13381 |
0.414 |
|
| 2010 |
Brady BL, Steinel NC, Bassing CH. Antigen receptor allelic exclusion: an update and reappraisal. Journal of Immunology (Baltimore, Md. : 1950). 185: 3801-8. PMID 20858891 DOI: 10.4049/Jimmunol.1001158 |
0.784 |
|
| 2010 |
Brady BL, Oropallo MA, Yang-Iott KS, Serwold T, Hochedlinger K, Jaenisch R, Weissman IL, Bassing CH. Position-dependent silencing of germline Vß segments on TCRß alleles containing preassembled VßDJßCß1 genes. Journal of Immunology (Baltimore, Md. : 1950). 185: 3564-73. PMID 20709953 DOI: 10.4049/Jimmunol.0903098 |
0.638 |
|
| 2010 |
Zha S, Bassing CH, Sanda T, Brush JW, Patel H, Goff PH, Murphy MM, Tepsuporn S, Gatti RA, Look AT, Alt FW. ATM-deficient thymic lymphoma is associated with aberrant tcrd rearrangement and gene amplification. The Journal of Experimental Medicine. 207: 1369-80. PMID 20566716 DOI: 10.1084/Jem.20100285 |
0.481 |
|
| 2010 |
Steinel NC, Brady BL, Carpenter AC, Yang-Iott KS, Bassing CH. Posttranscriptional silencing of VbetaDJbetaCbeta genes contributes to TCRbeta allelic exclusion in mammalian lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 185: 1055-62. PMID 20562258 DOI: 10.4049/Jimmunol.0903099 |
0.801 |
|
| 2010 |
Liu X, Karnell JL, Yin B, Zhang R, Zhang J, Li P, Choi Y, Maltzman JS, Pear WS, Bassing CH, Turka LA. Distinct roles for PTEN in prevention of T cell lymphoma and autoimmunity in mice. The Journal of Clinical Investigation. 120: 2497-507. PMID 20516645 DOI: 10.1172/Jci42382 |
0.65 |
|
| 2010 |
Yang-Iott KS, Carpenter AC, Rowh MA, Steinel N, Brady BL, Hochedlinger K, Jaenisch R, Bassing CH. TCR beta feedback signals inhibit the coupling of recombinationally accessible V beta 14 segments with DJ beta complexes. Journal of Immunology (Baltimore, Md. : 1950). 184: 1369-78. PMID 20042591 DOI: 10.4049/Jimmunol.0900723 |
0.745 |
|
| 2010 |
Hewitt SL, Yin B, Ji Y, Chaumeil J, Marszalek K, Tenthorey J, Salvagiotto G, Steinel N, Ramsey LB, Ghysdael J, Farrar MA, Sleckman BP, Schatz DG, Busslinger M, Bassing CH, et al. Addendum: RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci Nature Immunology. 11: 355-356. DOI: 10.1038/Ni0410-355 |
0.763 |
|
| 2009 |
Yin B, Savic V, Juntilla MM, Bredemeyer AL, Yang-Iott KS, Helmink BA, Koretzky GA, Sleckman BP, Bassing CH. Histone H2AX stabilizes broken DNA strands to suppress chromosome breaks and translocations during V(D)J recombination. The Journal of Experimental Medicine. 206: 2625-39. PMID 19887394 DOI: 10.1084/Jem.20091320 |
0.754 |
|
| 2009 |
Mahowald GK, Baron JM, Mahowald MA, Kulkarni S, Bredemeyer AL, Bassing CH, Sleckman BP. Aberrantly resolved RAG-mediated DNA breaks in Atm-deficient lymphocytes target chromosomal breakpoints in cis. Proceedings of the National Academy of Sciences of the United States of America. 106: 18339-44. PMID 19820166 DOI: 10.1073/Pnas.0902545106 |
0.422 |
|
| 2009 |
Savic V, Sanborn KB, Orange JS, Bassing CH. Chipping away at gamma-H2AX foci. Cell Cycle (Georgetown, Tex.). 8: 3285-90. PMID 19770593 DOI: 10.4161/Cc.8.20.9719 |
0.643 |
|
| 2009 |
Yin B, Bassing CH. V(D)J recombination causes dangerous chromosome liaisons in developing thymocytes. Cell Cycle (Georgetown, Tex.). 8: 2486-7. PMID 19684464 DOI: 10.4161/Cc.8.16.9349 |
0.614 |
|
| 2009 |
Kadariya Y, Yin B, Tang B, Shinton SA, Quinlivan EP, Hua X, Klein-Szanto A, Al-Saleem TI, Bassing CH, Hardy RR, Kruger WD. Mice heterozygous for germ-line mutations in methylthioadenosine phosphorylase (MTAP) die prematurely of T-cell lymphoma. Cancer Research. 69: 5961-9. PMID 19567676 DOI: 10.1158/0008-5472.Can-09-0145 |
0.624 |
|
| 2009 |
Savic V, Yin B, Maas NL, Bredemeyer AL, Carpenter AC, Helmink BA, Yang-Iott KS, Sleckman BP, Bassing CH. Formation of dynamic gamma-H2AX domains along broken DNA strands is distinctly regulated by ATM and MDC1 and dependent upon H2AX densities in chromatin. Molecular Cell. 34: 298-310. PMID 19450528 DOI: 10.1016/J.Molcel.2009.04.012 |
0.774 |
|
| 2009 |
Hewitt SL, Yin B, Ji Y, Chaumeil J, Marszalek K, Tenthorey J, Salvagiotto G, Steinel N, Ramsey LB, Ghysdael J, Farrar MA, Sleckman BP, Schatz DG, Busslinger M, Bassing CH, et al. RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci. Nature Immunology. 10: 655-64. PMID 19448632 DOI: 10.1038/Ni.1735 |
0.802 |
|
| 2009 |
Carpenter AC, Yang-Iott KS, Chao LH, Nuskey B, Whitlow S, Alt FW, Bassing CH. Assembled DJ beta complexes influence TCR beta chain selection and peripheral V beta repertoire. Journal of Immunology (Baltimore, Md. : 1950). 182: 5586-95. PMID 19380806 DOI: 10.4049/Jimmunol.0803270 |
0.711 |
|
| 2009 |
Economopoulou M, Langer HF, Celeste A, Orlova VV, Choi EY, Ma M, Vassilopoulos A, Callen E, Deng C, Bassing CH, Boehm M, Nussenzweig A, Chavakis T. Histone H2AX is integral to hypoxia-driven neovascularization. Nature Medicine. 15: 553-8. PMID 19377486 DOI: 10.1038/Nm.1947 |
0.37 |
|
| 2009 |
Helmink BA, Bredemeyer AL, Lee BS, Huang CY, Sharma GG, Walker LM, Bednarski JJ, Lee WL, Pandita TK, Bassing CH, Sleckman BP. MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks. The Journal of Experimental Medicine. 206: 669-79. PMID 19221393 DOI: 10.1084/Jem.20081326 |
0.44 |
|
| 2009 |
Chanoux RA, Yin B, Urtishak KA, Asare A, Bassing CH, Brown EJ. ATR and H2AX cooperate in maintaining genome stability under replication stress. The Journal of Biological Chemistry. 284: 5994-6003. PMID 19049966 DOI: 10.1074/Jbc.M806739200 |
0.61 |
|
| 2009 |
Hewitt SL, Yin B, Ji Y, Chaumeil J, Marszalek K, Tenthorey J, Salvagiotto G, Steinel N, Ramsey LB, Ghysdael J, A Farrar M, Sleckman BP, Schatz DG, Busslinger M, Bassing CH, et al. Erratum: Corrigendum: RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci Nature Immunology. 10: 1034-1034. DOI: 10.1038/Ni0909-1034 |
0.741 |
|
| 2008 |
Bredemeyer AL, Helmink BA, Innes CL, Calderon B, McGinnis LM, Mahowald GK, Gapud EJ, Walker LM, Collins JB, Weaver BK, Mandik-Nayak L, Schreiber RD, Allen PM, May MJ, Paules RS, ... Bassing CH, et al. DNA double-strand breaks activate a multi-functional genetic program in developing lymphocytes. Nature. 456: 819-23. PMID 18849970 DOI: 10.1038/Nature07392 |
0.411 |
|
| 2008 |
Pontano LL, Aggarwal P, Barbash O, Brown EJ, Bassing CH, Diehl JA. Genotoxic stress-induced cyclin D1 phosphorylation and proteolysis are required for genomic stability. Molecular and Cellular Biology. 28: 7245-58. PMID 18809569 DOI: 10.1128/Mcb.01085-08 |
0.35 |
|
| 2008 |
Bassing CH, Whitlow S, Mostoslavsky R, Mostoslovasky R, Yang-Iott K, Ranganath S, Alt FW. Vbeta cluster sequences reduce the frequency of primary Vbeta2 and Vbeta14 rearrangements. European Journal of Immunology. 38: 2564-72. PMID 18792409 DOI: 10.1002/Eji.200838347 |
0.401 |
|
| 2008 |
Bredemeyer AL, Huang CY, Walker LM, Bassing CH, Sleckman BP. Aberrant V(D)J recombination in ataxia telangiectasia mutated-deficient lymphocytes is dependent on nonhomologous DNA end joining. Journal of Immunology (Baltimore, Md. : 1950). 181: 2620-5. PMID 18684952 DOI: 10.4049/Jimmunol.181.4.2620 |
0.412 |
|
| 2008 |
Yin B, Bassing CH. The sticky business of histone H2AX in V(D)J recombination, maintenance of genomic stability, and suppression of lymphoma. Immunologic Research. 42: 29-40. PMID 18622584 DOI: 10.1007/S12026-008-8030-4 |
0.628 |
|
| 2008 |
Zha S, Sekiguchi J, Brush JW, Bassing CH, Alt FW. Complementary functions of ATM and H2AX in development and suppression of genomic instability. Proceedings of the National Academy of Sciences of the United States of America. 105: 9302-6. PMID 18599436 DOI: 10.1073/Pnas.0803520105 |
0.383 |
|
| 2008 |
Rowh MA, Bassing CH. Foxos around make B cells tolerable. Nature Immunology. 9: 586-8. PMID 18490907 DOI: 10.1038/Ni0608-586 |
0.784 |
|
| 2008 |
Ranganath S, Carpenter AC, Gleason M, Shaw AC, Bassing CH, Alt FW. Productive coupling of accessible Vbeta14 segments and DJbeta complexes determines the frequency of Vbeta14 rearrangement. Journal of Immunology (Baltimore, Md. : 1950). 180: 2339-46. PMID 18250443 DOI: 10.4049/Jimmunol.180.4.2339 |
0.723 |
|
| 2008 |
Huang CY, Bredemeyer AL, Walker LM, Bassing CH, Sleckman BP. Dynamic regulation of c-Myc proto-oncogene expression during lymphocyte development revealed by a GFP-c-Myc knock-in mouse. European Journal of Immunology. 38: 342-9. PMID 18196519 DOI: 10.1002/Eji.200737972 |
0.363 |
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| 2008 |
Bassing CH, Ranganath S, Murphy M, Savic V, Gleason M, Alt FW. Aberrant V(D)J recombination is not required for rapid development of H2ax/p53-deficient thymic lymphomas with clonal translocations. Blood. 111: 2163-9. PMID 17855626 DOI: 10.1182/Blood-2007-08-104760 |
0.683 |
|
| 2008 |
Lin DI, Lessie MD, Gladden AB, Bassing CH, Wagner KU, Diehl JA. Disruption of cyclin D1 nuclear export and proteolysis accelerates mammary carcinogenesis Oncogene. 27: 1231-1242. PMID 17724472 DOI: 10.1038/Sj.Onc.1210738 |
0.348 |
|
| 2007 |
Yin B, Savic V, Bassing CH. ATM prevents unattended DNA double strand breaks on site and in generations to come. Cancer Biology & Therapy. 6: 1837-9. PMID 18087222 DOI: 10.4161/Cbt.6.12.5336 |
0.755 |
|
| 2007 |
Aggarwal P, Lessie MD, Lin DI, Pontano L, Gladden AB, Nuskey B, Goradia A, Wasik MA, Klein-Szanto AJ, Rustgi AK, Bassing CH, Diehl JA. Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication. Genes & Development. 21: 2908-22. PMID 18006686 DOI: 10.1101/Gad.1586007 |
0.41 |
|
| 2007 |
Huang CY, Sharma GG, Walker LM, Bassing CH, Pandita TK, Sleckman BP. Defects in coding joint formation in vivo in developing ATM-deficient B and T lymphocytes. The Journal of Experimental Medicine. 204: 1371-81. PMID 17502661 DOI: 10.1084/Jem.20061460 |
0.428 |
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| 2007 |
Wu C, Ranganath S, Gleason M, Woodman BB, Borjeson TM, Alt FW, Bassing CH. Restriction of endogenous T cell antigen receptor beta rearrangements to Vbeta14 through selective recombination signal sequence modifications. Proceedings of the National Academy of Sciences of the United States of America. 104: 4002-7. PMID 17360467 DOI: 10.1073/Pnas.0700081104 |
0.438 |
|
| 2006 |
Carpenter AC, Bassing CH. Fetal thymocyte development: putting a zinc finger on it? Nature Immunology. 7: 1285-6. PMID 17110947 DOI: 10.1038/Ni1206-1285 |
0.691 |
|
| 2006 |
Bredemeyer AL, Sharma GG, Huang CY, Helmink BA, Walker LM, Khor KC, Nuskey B, Sullivan KE, Pandita TK, Bassing CH, Sleckman BP. ATM stabilizes DNA double-strand-break complexes during V(D)J recombination. Nature. 442: 466-70. PMID 16799570 DOI: 10.1038/Nature04866 |
0.447 |
|
| 2006 |
Aifantis I, Bassing CH, Garbe AI, Sawai K, Alt FW, von Boehmer H. The E delta enhancer controls the generation of CD4- CD8- alphabetaTCR-expressing T cells that can give rise to different lineages of alphabeta T cells. The Journal of Experimental Medicine. 203: 1543-50. PMID 16754716 DOI: 10.1084/Jem.20051711 |
0.345 |
|
| 2006 |
Morales JC, Franco S, Murphy MM, Bassing CH, Mills KD, Adams MM, Walsh NC, Manis JP, Rassidakis GZ, Alt FW, Carpenter PB. 53BP1 and p53 synergize to suppress genomic instability and lymphomagenesis. Proceedings of the National Academy of Sciences of the United States of America. 103: 3310-5. PMID 16492765 DOI: 10.1073/Pnas.0511259103 |
0.418 |
|
| 2006 |
Franco S, Gostissa M, Zha S, Lombard DB, Murphy MM, Zarrin AA, Yan C, Tepsuporn S, Morales JC, Adams MM, Lou Z, Bassing CH, Manis JP, Chen J, Carpenter PB, et al. H2AX prevents DNA breaks from progressing to chromosome breaks and translocations. Molecular Cell. 21: 201-14. PMID 16427010 DOI: 10.1016/J.Molcel.2006.01.005 |
0.448 |
|
| 2006 |
O'Neil J, Calvo J, McKenna K, Krishnamoorthy V, Aster JC, Bassing CH, Alt FW, Kelliher M, Look AT. Activating Notch1 mutations in mouse models of T-ALL. Blood. 107: 781-5. PMID 16166587 DOI: 10.1182/Blood-2005-06-2553 |
0.374 |
|
| 2005 |
Perlot T, Alt FW, Bassing CH, Suh H, Pinaud E. Elucidation of IgH intronic enhancer functions via germ-line deletion. Proceedings of the National Academy of Sciences of the United States of America. 102: 14362-7. PMID 16186486 DOI: 10.1073/Pnas.0507090102 |
0.395 |
|
| 2005 |
Dudley DD, Chaudhuri J, Bassing CH, Alt FW. Mechanism and control of V(D)J recombination versus class switch recombination: similarities and differences. Advances in Immunology. 86: 43-112. PMID 15705419 DOI: 10.1016/S0065-2776(04)86002-4 |
0.476 |
|
| 2005 |
Kang J, Ferguson D, Song H, Bassing C, Eckersdorff M, Alt FW, Xu Y. Functional interaction of H2AX, NBS1, and p53 in ATM-dependent DNA damage responses and tumor suppression. Molecular and Cellular Biology. 25: 661-70. PMID 15632067 DOI: 10.1128/Mcb.25.2.661-670.2005 |
0.387 |
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| 2004 |
Xie A, Puget N, Shim I, Odate S, Jarzyna I, Bassing CH, Alt FW, Scully R. Control of sister chromatid recombination by histone H2AX. Molecular Cell. 16: 1017-25. PMID 15610743 DOI: 10.1016/J.Molcel.2004.12.007 |
0.383 |
|
| 2004 |
Ansel KM, Greenwald RJ, Agarwal S, Bassing CH, Monticelli S, Interlandi J, Djuretic IM, Lee DU, Sharpe AH, Alt FW, Rao A. Deletion of a conserved Il4 silencer impairs T helper type 1-mediated immunity. Nature Immunology. 5: 1251-9. PMID 15516924 DOI: 10.1038/Ni1135 |
0.345 |
|
| 2004 |
Bassing CH, Alt FW. The cellular response to general and programmed DNA double strand breaks. Dna Repair. 3: 781-96. PMID 15279764 DOI: 10.1016/J.Dnarep.2004.06.001 |
0.414 |
|
| 2004 |
Giallourakis C, Alt FW, Bassing CH. V(D)J recombinational accessibility-heading in the opposite direction? Nature Immunology. 5: 561-2. PMID 15164012 DOI: 10.1038/Ni0604-561 |
0.405 |
|
| 2003 |
Dudley DD, Sekiguchi J, Zhu C, Sadofsky MJ, Whitlow S, DeVido J, Monroe RJ, Bassing CH, Alt FW. Impaired V(D)J recombination and lymphocyte development in core RAG1-expressing mice. The Journal of Experimental Medicine. 198: 1439-50. PMID 14581608 DOI: 10.1084/Jem.20030627 |
0.406 |
|
| 2003 |
Bassing CH, Suh H, Ferguson DO, Chua KF, Manis J, Eckersdorff M, Gleason M, Bronson R, Lee C, Alt FW. Histone H2AX: a dosage-dependent suppressor of oncogenic translocations and tumors. Cell. 114: 359-70. PMID 12914700 DOI: 10.1016/S0092-8674(03)00566-X |
0.464 |
|
| 2003 |
Mostoslavsky R, Alt FW, Bassing CH. Chromatin dynamics and locus accessibility in the immune system. Nature Immunology. 4: 603-6. PMID 12830134 DOI: 10.1038/Ni0703-603 |
0.38 |
|
| 2003 |
Akamatsu Y, Monroe R, Dudley DD, Elkin SK, Gartner F, Talukder SR, Takahama Y, Alt FW, Bassing CH, Oettinger MA. Deletion of the RAG2 C terminus leads to impaired lymphoid development in mice. Proceedings of the National Academy of Sciences of the United States of America. 100: 1209-14. PMID 12531919 DOI: 10.1073/Pnas.0237043100 |
0.487 |
|
| 2003 |
Wu C, Bassing CH, Jung D, Woodman BB, Foy D, Alt FW. Dramatically increased rearrangement and peripheral representation of Vbeta14 driven by the 3'Dbeta1 recombination signal sequence. Immunity. 18: 75-85. PMID 12530977 DOI: 10.1016/S1074-7613(02)00515-0 |
0.375 |
|
| 2003 |
Jung D, Bassing CH, Fugmann SD, Cheng HL, Schatz DG, Alt FW. Extrachromosomal recombination substrates recapitulate beyond 12/23 restricted VDJ recombination in nonlymphoid cells. Immunity. 18: 65-74. PMID 12530976 DOI: 10.1016/S1074-7613(02)00507-1 |
0.391 |
|
| 2002 |
Solymar DC, Agarwal S, Bassing CH, Alt FW, Rao A. A 3' enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells. Immunity. 17: 41-50. PMID 12150890 DOI: 10.1016/S1074-7613(02)00334-5 |
0.32 |
|
| 2002 |
Ye Q, Press B, Kissler S, Yang XF, Lu L, Bassing CH, Sleckman BP, Jansson M, Panoutsakopoulou V, Trimble LA, Alt FW, Cantor H. T cell costimulation through CD28 depends on induction of the Bcl-xgamma isoform: analysis of Bcl-xgamma-deficient mice. The Journal of Experimental Medicine. 196: 87-95. PMID 12093873 DOI: 10.1084/Jem.20012084 |
0.374 |
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| 2002 |
Bassing CH, Chua KF, Sekiguchi J, Suh H, Whitlow SR, Fleming JC, Monroe BC, Ciccone DN, Yan C, Vlasakova K, Livingston DM, Ferguson DO, Scully R, Alt FW. Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX. Proceedings of the National Academy of Sciences of the United States of America. 99: 8173-8. PMID 12034884 DOI: 10.1073/Pnas.122228699 |
0.431 |
|
| 2002 |
Bassing CH, Swat W, Alt FW. The mechanism and regulation of chromosomal V(D)J recombination. Cell. 109: S45-55. PMID 11983152 DOI: 10.1016/S0092-8674(02)00675-X |
0.368 |
|
| 2000 |
Sleckman BP, Bassing CH, Hughes MM, Okada A, D'Auteuil M, Wehrly TD, Woodman BB, Davidson L, Chen J, Alt FW. Mechanisms that direct ordered assembly of T cell receptor beta locus V, D, and J gene segments. Proceedings of the National Academy of Sciences of the United States of America. 97: 7975-80. PMID 10869424 DOI: 10.1073/Pnas.130190597 |
0.393 |
|
| 2000 |
Bassing CH, Alt FW, Hughes MM, D'Auteuil M, Wehrly TD, Woodman BB, Gärtner F, White JM, Davidson L, Sleckman BP. Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule. Nature. 405: 583-6. PMID 10850719 DOI: 10.1038/35014635 |
0.454 |
|
| 2000 |
Sleckman BP, Khan WN, Xu W, Bassing CH, Malynn BA, Copeland NG, Bardon CG, Breit TM, Davidson L, Oltz EM, Jenkins NA, Berman JE, Alt FW. Cloning and functional characterization of the early-lymphocyte-specific Pb99 gene. Molecular and Cellular Biology. 20: 4405-10. PMID 10825203 DOI: 10.1128/Mcb.20.12.4405-4410.2000 |
0.422 |
|
| 1998 |
Sleckman BP, Bassing CH, Bardon CG, Okada A, Khor B, Bories JC, Monroe R, Alt FW. Accessibility control of variable region gene assembly during T-cell development. Immunological Reviews. 165: 121-30. PMID 9850857 DOI: 10.1111/J.1600-065X.1998.Tb01235.X |
0.402 |
|
| 1994 |
Bassing CH, Yingling JM, Howe DJ, Wang T, He WW, Gustafson ML, Shah P, Donahoe PK, Wang XF. A transforming growth factor β type I receptor that signals to activate gene expression Science. 263: 87-89. PMID 8272871 DOI: 10.1126/Science.8272871 |
0.302 |
|
| 1993 |
Pendergast AM, Quilliam LA, Cripe LD, Bassing CH, Dai Z, Li N, Batzer A, Rabun KM, Der CJ, Schlessinger J, Gishizky ML. BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein Cell. 75: 175-185. DOI: 10.1016/S0092-8674(05)80094-7 |
0.31 |
|
| 1992 |
Bassing CH, Kim YG, Li L, Chandrasegaran S. Overproduction, purification and characterization of M·HinfI methyltransferase and its deletion mutant Gene. 113: 83-88. PMID 1563635 DOI: 10.1016/0378-1119(92)90672-C |
0.37 |
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