| Year |
Citation |
Score |
| 2020 |
Mancl JM, Suarez C, Liang WG, Kovar DR, Tang WJ. exoenzyme Y directly bundles actin filaments. The Journal of Biological Chemistry. PMID 32019868 DOI: 10.1074/Jbc.Ra119.012320 |
0.304 |
|
| 2019 |
Leroux F, Bosc D, Beghyn T, Hermant P, Warenghem S, Landry V, Pottiez V, Guillaume V, Charton J, Herledan A, Urata S, Liang W, Sheng L, Tang WJ, Deprez B, et al. Identification of ebselen as a potent inhibitor of insulin degrading enzyme by a drug repurposing screening. European Journal of Medicinal Chemistry. 179: 557-566. PMID 31276900 DOI: 10.1016/J.Ejmech.2019.06.057 |
0.3 |
|
| 2016 |
Liang WG, Triandafillou CG, Huang TY, Zulueta MM, Banerjee S, Dinner AR, Hung SC, Tang WJ. Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3. Proceedings of the National Academy of Sciences of the United States of America. PMID 27091995 DOI: 10.1073/Pnas.1523981113 |
0.375 |
|
| 2015 |
Lübker C, Dove S, Tang WJ, Urbauer RJ, Moskovitz J, Urbauer JL, Seifert R. Different Roles of N-Terminal and C-Terminal Domains in Calmodulin for Activation of Bacillus anthracis Edema Factor. Toxins. 7: 2598-614. PMID 26184312 DOI: 10.3390/Toxins7072598 |
0.383 |
|
| 2015 |
Liang WG, Ren M, Zhao F, Tang WJ. Structures of human CCL18, CCL3, and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme. Journal of Molecular Biology. 427: 1345-58. PMID 25636406 DOI: 10.1016/J.Jmb.2015.01.012 |
0.338 |
|
| 2014 |
King JV, Liang WG, Scherpelz KP, Schilling AB, Meredith SC, Tang WJ. Molecular basis of substrate recognition and degradation by human presequence protease. Structure (London, England : 1993). 22: 996-1007. PMID 24931469 DOI: 10.1016/J.Str.2014.05.003 |
0.305 |
|
| 2014 |
Charton J, Gauriot M, Guo Q, Hennuyer N, Marechal X, Dumont J, Hamdane M, Pottiez V, Landry V, Sperandio O, Flipo M, Buee L, Staels B, Leroux F, Tang WJ, et al. Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-β hydrolysis. European Journal of Medicinal Chemistry. 79: 184-93. PMID 24735644 DOI: 10.1016/J.Ejmech.2014.04.009 |
0.313 |
|
| 2013 |
Beste KY, Spangler CM, Burhenne H, Koch KW, Shen Y, Tang WJ, Kaever V, Seifert R. Nucleotidyl cyclase activity of particulate guanylyl cyclase A: comparison with particulate guanylyl cyclases E and F, soluble guanylyl cyclase and bacterial adenylyl cyclases CyaA and edema factor. Plos One. 8: e70223. PMID 23922959 DOI: 10.1371/Journal.Pone.0070223 |
0.366 |
|
| 2013 |
McCord LA, Liang WG, Dowdell E, Kalas V, Hoey RJ, Koide A, Koide S, Tang WJ. Conformational states and recognition of amyloidogenic peptides of human insulin-degrading enzyme. Proceedings of the National Academy of Sciences of the United States of America. 110: 13827-32. PMID 23922390 DOI: 10.1073/Pnas.1304575110 |
0.324 |
|
| 2013 |
Tripathi A, Saini V, Marchese A, Volkman BF, Tang WJ, Majetschak M. Modulation of the CXC chemokine receptor 4 agonist activity of ubiquitin through C-terminal protein modification. Biochemistry. 52: 4184-92. PMID 23697661 DOI: 10.1021/Bi400254F |
0.367 |
|
| 2013 |
Mones L, Tang WJ, Florián J. Empirical valence bond simulations of the chemical mechanism of ATP to cAMP conversion by anthrax edema factor. Biochemistry. 52: 2672-82. PMID 23480863 DOI: 10.1021/Bi400088Y |
0.309 |
|
| 2012 |
Schuler D, Lübker C, Lushington GH, Tang WJ, Shen Y, Richter M, Seifert R. Interactions of Bordetella pertussis adenylyl cyclase toxin CyaA with calmodulin mutants and calmodulin antagonists: comparison with membranous adenylyl cyclase I. Biochemical Pharmacology. 83: 839-48. PMID 22265637 DOI: 10.1016/J.Bcp.2012.01.005 |
0.383 |
|
| 2012 |
Taha H, Dove S, Geduhn J, König B, Shen Y, Tang WJ, Seifert R. Inhibition of the adenylyl cyclase toxin, edema factor, from Bacillus anthracis by a series of 18 mono- and bis-(M)ANT-substituted nucleoside 5'-triphosphates. Naunyn-Schmiedeberg's Archives of Pharmacology. 385: 57-68. PMID 21947230 DOI: 10.1007/S00210-011-0688-9 |
0.378 |
|
| 2011 |
Saini V, Marchese A, Tang WJ, Majetschak M. Structural determinants of ubiquitin-CXC chemokine receptor 4 interaction. The Journal of Biological Chemistry. 286: 44145-52. PMID 22039044 DOI: 10.1074/Jbc.M111.298505 |
0.409 |
|
| 2011 |
Cortright JJ, Lorrain DS, Beeler JA, Tang WJ, Vezina P. Previous exposure to delta9-tetrahydrocannibinol enhances locomotor responding to but not self-administration of amphetamine. The Journal of Pharmacology and Experimental Therapeutics. 337: 724-33. PMID 21389094 DOI: 10.1124/Jpet.111.180208 |
0.563 |
|
| 2011 |
Geduhn J, Dove S, Shen Y, Tang WJ, König B, Seifert R. Bis-halogen-anthraniloyl-substituted nucleoside 5'-triphosphates as potent and selective inhibitors of Bordetella pertussis adenylyl cyclase toxin. The Journal of Pharmacology and Experimental Therapeutics. 336: 104-15. PMID 20962032 DOI: 10.1124/Jpet.110.174219 |
0.346 |
|
| 2010 |
Ren M, Guo Q, Guo L, Lenz M, Qian F, Koenen RR, Xu H, Schilling AB, Weber C, Ye RD, Dinner AR, Tang WJ. Polymerization of MIP-1 chemokine (CCL3 and CCL4) and clearance of MIP-1 by insulin-degrading enzyme. The Embo Journal. 29: 3952-66. PMID 20959807 DOI: 10.1038/Emboj.2010.256 |
0.323 |
|
| 2010 |
Duverger A, Carré JM, Jee J, Leppla SH, Cormet-Boyaka E, Tang WJ, Tomé D, Boyaka PN. Contributions of edema factor and protective antigen to the induction of protective immunity by Bacillus anthracis edema toxin as an intranasal adjuvant. Journal of Immunology (Baltimore, Md. : 1950). 185: 5943-52. PMID 20952678 DOI: 10.4049/Jimmunol.0902795 |
0.323 |
|
| 2010 |
Laine E, Goncalves C, Karst JC, Lesnard A, Rault S, Tang WJ, Malliavin TE, Ladant D, Blondel A. Use of allostery to identify inhibitors of calmodulin-induced activation of Bacillus anthracis edema factor. Proceedings of the National Academy of Sciences of the United States of America. 107: 11277-82. PMID 20534570 DOI: 10.1073/Pnas.0914611107 |
0.401 |
|
| 2010 |
Göttle M, Dove S, Kees F, Schlossmann J, Geduhn J, König B, Shen Y, Tang WJ, Kaever V, Seifert R. Cytidylyl and uridylyl cyclase activity of bacillus anthracis edema factor and Bordetella pertussis CyaA. Biochemistry. 49: 5494-503. PMID 20521845 DOI: 10.1021/Bi100684G |
0.402 |
|
| 2010 |
Guo Q, Manolopoulou M, Bian Y, Schilling AB, Tang WJ. Molecular basis for the recognition and cleavages of IGF-II, TGF-alpha, and amylin by human insulin-degrading enzyme. Journal of Molecular Biology. 395: 430-43. PMID 19896952 DOI: 10.1016/J.Jmb.2009.10.072 |
0.341 |
|
| 2009 |
Ralat LA, Ren M, Schilling AB, Tang WJ. Protective role of Cys-178 against the inactivation and oligomerization of human insulin-degrading enzyme by oxidation and nitrosylation. The Journal of Biological Chemistry. 284: 34005-18. PMID 19808678 DOI: 10.1074/Jbc.M109.030627 |
0.32 |
|
| 2009 |
Tang WJ, Guo Q. The adenylyl cyclase activity of anthrax edema factor. Molecular Aspects of Medicine. 30: 423-30. PMID 19560485 DOI: 10.1016/J.Mam.2009.06.001 |
0.43 |
|
| 2009 |
Suryanarayana S, Wang JL, Richter M, Shen Y, Tang WJ, Lushington GH, Seifert R. Distinct interactions of 2'- and 3'-O-(N-methyl)anthraniloyl-isomers of ATP and GTP with the adenylyl cyclase toxin of Bacillus anthracis, edema factor. Biochemical Pharmacology. 78: 224-30. PMID 19492438 DOI: 10.1016/J.Bcp.2009.04.006 |
0.397 |
|
| 2009 |
Szarowicz SE, During RL, Li W, Quinn CP, Tang WJ, Southwick FS. Bacillus anthracis edema toxin impairs neutrophil actin-based motility. Infection and Immunity. 77: 2455-64. PMID 19349425 DOI: 10.1128/Iai.00839-08 |
0.313 |
|
| 2009 |
Bourdeau RW, Malito E, Chenal A, Bishop BL, Musch MW, Villereal ML, Chang EB, Mosser EM, Rest RF, Tang WJ. Cellular functions and X-ray structure of anthrolysin O, a cholesterol-dependent cytolysin secreted by Bacillus anthracis. The Journal of Biological Chemistry. 284: 14645-56. PMID 19307185 DOI: 10.1074/Jbc.M807631200 |
0.352 |
|
| 2009 |
Taha HM, Schmidt J, Göttle M, Suryanarayana S, Shen Y, Tang WJ, Gille A, Geduhn J, König B, Dove S, Seifert R. Molecular analysis of the interaction of anthrax adenylyl cyclase toxin, edema factor, with 2'(3')-O-(N-(methyl)anthraniloyl)-substituted purine and pyrimidine nucleotides. Molecular Pharmacology. 75: 693-703. PMID 19056899 DOI: 10.1124/Mol.108.052340 |
0.425 |
|
| 2008 |
Malito E, Ralat LA, Manolopoulou M, Tsay JL, Wadlington NL, Tang WJ. Molecular bases for the recognition of short peptide substrates and cysteine-directed modifications of human insulin-degrading enzyme. Biochemistry. 47: 12822-34. PMID 18986166 DOI: 10.1021/Bi801192H |
0.385 |
|
| 2008 |
Spangler CM, Spangler C, Göttle M, Shen Y, Tang WJ, Seifert R, Schäferling M. A fluorimetric assay for real-time monitoring of adenylyl cyclase activity based on terbium norfloxacin. Analytical Biochemistry. 381: 86-93. PMID 18601890 DOI: 10.1016/J.Ab.2008.06.014 |
0.342 |
|
| 2008 |
Guo Q, Jureller JE, Warren JT, Solomaha E, Florián J, Tang WJ. Protein-protein docking and analysis reveal that two homologous bacterial adenylyl cyclase toxins interact with calmodulin differently. The Journal of Biological Chemistry. 283: 23836-45. PMID 18583346 DOI: 10.1074/Jbc.M802168200 |
0.453 |
|
| 2008 |
Kim C, Wilcox-Adelman S, Sano Y, Tang WJ, Collier RJ, Park JM. Antiinflammatory cAMP signaling and cell migration genes co-opted by the anthrax bacillus. Proceedings of the National Academy of Sciences of the United States of America. 105: 6150-5. PMID 18427110 DOI: 10.1073/Pnas.0800105105 |
0.317 |
|
| 2007 |
Warren JT, Guo Q, Tang WJ. A 1.3-A structure of zinc-bound N-terminal domain of calmodulin elucidates potential early ion-binding step. Journal of Molecular Biology. 374: 517-27. PMID 17942116 DOI: 10.1016/J.Jmb.2007.09.048 |
0.403 |
|
| 2007 |
Johnson EC, Malito E, Shen Y, Pentelute B, Rich D, Florián J, Tang WJ, Kent SB. Insights from atomic-resolution X-ray structures of chemically synthesized HIV-1 protease in complex with inhibitors. Journal of Molecular Biology. 373: 573-86. PMID 17869270 DOI: 10.1016/J.Jmb.2007.07.054 |
0.3 |
|
| 2007 |
Johnson EC, Malito E, Shen Y, Rich D, Tang WJ, Kent SB. Modular total chemical synthesis of a human immunodeficiency virus type 1 protease. Journal of the American Chemical Society. 129: 11480-90. PMID 17705484 DOI: 10.1021/Ja072870N |
0.306 |
|
| 2007 |
Im H, Manolopoulou M, Malito E, Shen Y, Zhao J, Neant-Fery M, Sun CY, Meredith SC, Sisodia SS, Leissring MA, Tang WJ. Structure of substrate-free human insulin-degrading enzyme (IDE) and biophysical analysis of ATP-induced conformational switch of IDE. The Journal of Biological Chemistry. 282: 25453-63. PMID 17613531 DOI: 10.1074/Jbc.M701590200 |
0.401 |
|
| 2007 |
Göttle M, Dove S, Steindel P, Shen Y, Tang WJ, Geduhn J, König B, Seifert R. Molecular analysis of the interaction of Bordetella pertussis adenylyl cyclase with fluorescent nucleotides Molecular Pharmacology. 72: 526-535. PMID 17553924 DOI: 10.1124/Mol.107.034413 |
0.371 |
|
| 2007 |
Li Q, Krogmann T, Ali MA, Tang WJ, Cohen JI. The amino terminus of varicella-zoster virus (VZV) glycoprotein E is required for binding to insulin-degrading enzyme, a VZV receptor. Journal of Virology. 81: 8525-32. PMID 17553876 DOI: 10.1128/Jvi.00286-07 |
0.327 |
|
| 2006 |
Shen Y, Joachimiak A, Rosner MR, Tang WJ. Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism. Nature. 443: 870-4. PMID 17051221 DOI: 10.1038/Nature05143 |
0.338 |
|
| 2006 |
Li P, Kuo WL, Yousef M, Rosner MR, Tang WJ. The C-terminal domain of human insulin degrading enzyme is required for dimerization and substrate recognition. Biochemical and Biophysical Research Communications. 343: 1032-7. PMID 16574064 DOI: 10.1016/J.Bbrc.2006.03.083 |
0.339 |
|
| 2005 |
Guo Q, Shen Y, Lee YS, Gibbs CS, Mrksich M, Tang WJ. Structural basis for the interaction of Bordetella pertussis adenylyl cyclase toxin with calmodulin Embo Journal. 24: 3190-3201. PMID 16138079 DOI: 10.1038/Sj.Emboj.7600800 |
0.33 |
|
| 2005 |
Hong J, Beeler J, Zhukovskaya NL, He W, Tang WJ, Rosner MR. Anthrax edema factor potency depends on mode of cell entry. Biochemical and Biophysical Research Communications. 335: 850-7. PMID 16099427 DOI: 10.1016/J.Bbrc.2005.07.132 |
0.744 |
|
| 2005 |
Shen Y, Zhukovskaya NL, Guo Q, Florián J, Tang WJ. Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor. The Embo Journal. 24: 929-41. PMID 15719022 DOI: 10.1038/Sj.Emboj.7600574 |
0.757 |
|
| 2005 |
Paccani SR, Tonello F, Ghittoni R, Natale M, Muraro L, D'Elios MM, Tang WJ, Montecucco C, Baldari CT. Anthrax toxins suppress T lymphocyte activation by disrupting antigen receptor signaling. The Journal of Experimental Medicine. 201: 325-31. PMID 15699068 DOI: 10.1084/Jem.20041557 |
0.338 |
|
| 2004 |
Beeler JA, Yan SZ, Bykov S, Murza A, Asher S, Tang WJ. A soluble C1b protein and its regulation of soluble type 7 adenylyl cyclase. Biochemistry. 43: 15463-71. PMID 15581358 DOI: 10.1021/Bi049088+ |
0.651 |
|
| 2004 |
Guo Q, Shen Y, Zhukovskaya NL, Florián J, Tang WJ. Structural and kinetic analyses of the interaction of anthrax adenylyl cyclase toxin with reaction products cAMP and pyrophosphate. The Journal of Biological Chemistry. 279: 29427-35. PMID 15131111 DOI: 10.1074/Jbc.M402689200 |
0.76 |
|
| 2004 |
Shen Y, Guo Q, Zhukovskaya NL, Drum CL, Bohm A, Tang WJ. Structure of anthrax edema factor-calmodulin-adenosine 5'-(alpha,beta-methylene)-triphosphate complex reveals an alternative mode of ATP binding to the catalytic site. Biochemical and Biophysical Research Communications. 317: 309-14. PMID 15063758 DOI: 10.1016/J.Bbrc.2004.03.046 |
0.746 |
|
| 2004 |
Shen Y, Zhukovskaya NL, Zimmer MI, Soelaiman S, Bergson P, Wang CR, Gibbs CS, Tang WJ. Selective inhibition of anthrax edema factor by adefovir, a drug for chronic hepatitis B virus infection. Proceedings of the National Academy of Sciences of the United States of America. 101: 3242-7. PMID 14978283 DOI: 10.1073/Pnas.0306552101 |
0.74 |
|
| 2004 |
Beeler JA, Tang WJ. Expression and purification of soluble adenylyl cyclase from Escherichia coli. Methods in Molecular Biology (Clifton, N.J.). 237: 39-53. PMID 14501037 DOI: 10.1385/1-59259-430-1:39 |
0.585 |
|
| 2003 |
Ulmer TS, Soelaiman S, Li S, Klee CB, Tang WJ, Bax A. Calcium dependence of the interaction between calmodulin and anthrax edema factor. The Journal of Biological Chemistry. 278: 29261-6. PMID 12724328 DOI: 10.1074/Jbc.M302837200 |
0.327 |
|
| 2002 |
Drum CL, Yan SZ, Bard J, Shen YQ, Lu D, Soelaiman S, Grabarek Z, Bohm A, Tang WJ. Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin. Nature. 415: 396-402. PMID 11807546 DOI: 10.1038/415396A |
0.706 |
|
| 2001 |
Drum CL, Shen Y, Rice PA, Bohm A, Tang WJ. Crystallization and preliminary X-ray study of the edema factor exotoxin adenylyl cyclase domain from Bacillus anthracis in the presence of its activator, calmodulin. Acta Crystallographica. Section D, Biological Crystallography. 57: 1881-4. PMID 11717504 DOI: 10.1107/S0907444901014937 |
0.679 |
|
| 2001 |
Yan SZ, Beeler JA, Chen Y, Shelton RK, Tang WJ. The regulation of type 7 adenylyl cyclase by its C1b region and Escherichia coli peptidylprolyl isomerase, SlyD. The Journal of Biological Chemistry. 276: 8500-6. PMID 11113152 DOI: 10.1074/Jbc.M010361200 |
0.646 |
|
| 2000 |
Kudlacek O, Mitterauer T, Nanoff C, Hohenegger M, Tang WJ, Freissmuth M, Kleuss C. Inhibition of adenylyl and guanylyl cyclase isoforms by the antiviral drug foscarnet. The Journal of Biological Chemistry. 276: 3010-6. PMID 11050094 DOI: 10.1074/Jbc.M007910200 |
0.358 |
|
| 2000 |
Drum CL, Yan SZ, Sarac R, Mabuchi Y, Beckingham K, Bohm A, Grabarek Z, Tang WJ. An extended conformation of calmodulin induces interactions between the structural domains of adenylyl cyclase from Bacillus anthracis to promote catalysis. The Journal of Biological Chemistry. 275: 36334-40. PMID 10926933 DOI: 10.1074/Jbc.M004778200 |
0.716 |
|
| 1998 |
Mitterauer T, Hohenegger M, Tang WJ, Nanoff C, Freissmuth M. The C2 catalytic domain of adenylyl cyclase contains the second metal ion (Mn2+) binding site. Biochemistry. 37: 16183-91. PMID 9819210 DOI: 10.1021/Bi981441M |
0.394 |
|
| 1998 |
Tang WJ, Hurley JH. Catalytic mechanism and regulation of mammalian adenylyl cyclases. Molecular Pharmacology. 54: 231-40. PMID 9687563 DOI: 10.1124/Mol.54.2.231 |
0.32 |
|
| 1998 |
Yan S, Huang Z, Andrews RK, Tang W. Conversion of Forskolin-Insensitive to Forskolin-Sensitive (Mouse-Type IX) Adenylyl Cyclase Molecular Pharmacology. 53: 182-187. PMID 9463474 DOI: 10.1124/Mol.53.2.182 |
0.4 |
|
| 1998 |
Tang WJ, Yan S, Drum CL. Class III adenylyl cyclases: regulation and underlying mechanisms. Advances in Second Messenger and Phosphoprotein Research. 32: 137-51. PMID 9421589 DOI: 10.1016/S1040-7952(98)80009-8 |
0.587 |
|
| 1997 |
Yan SZ, Huang ZH, Rao VD, Hurley JH, Tang WJ. Three discrete regions of mammalian adenylyl cyclase form a site for Gsalpha activation. The Journal of Biological Chemistry. 272: 18849-54. PMID 9228061 DOI: 10.1074/Jbc.272.30.18849 |
0.335 |
|
| 1997 |
Yan S, Huang Z, Shaw RS, Tang W. The Conserved Asparagine and Arginine Are Essential for Catalysis of Mammalian Adenylyl Cyclase Journal of Biological Chemistry. 272: 12342-12349. PMID 9139678 DOI: 10.1074/Jbc.272.19.12342 |
0.372 |
|
| 1997 |
Zhang G, Liu Y, Qin J, Vo B, Tang WJ, Ruoho AE, Hurley JH. Characterization and crystallization of a minimal catalytic core domain from mammalian type II adenylyl cyclase. Protein Science : a Publication of the Protein Society. 6: 903-8. PMID 9098900 DOI: 10.1002/Pro.5560060417 |
0.357 |
|
| 1996 |
Robbins JD, Boring DL, Tang WJ, Shank R, Seamon KB. Forskolin carbamates: binding and activation studies with type I adenylyl cyclase. Journal of Medicinal Chemistry. 39: 2745-52. PMID 8709105 DOI: 10.1021/Jm960191+ |
0.349 |
|
| 1996 |
Yan SZ, Hahn D, Huang ZH, Tang WJ. Two cytoplasmic domains of mammalian adenylyl cyclase form a Gs alpha- and forskolin-activated enzyme in vitro. The Journal of Biological Chemistry. 271: 10941-5. PMID 8631912 DOI: 10.1074/Jbc.271.18.10941 |
0.372 |
|
| 1995 |
Tang WJ, Stanzel M, Gilman AG. Truncation and alanine-scanning mutants of type I adenylyl cyclase Biochemistry. 34: 14563-14572. PMID 7578062 DOI: 10.1021/Bi00044A035 |
0.382 |
|
| 1994 |
Sutkowski EM, Tang W, Broome CW, Robbins JD, Seamon KB. Regulation of forskolin interactions with type I, II, V, and VI adenylyl cyclases by Gs alpha. Biochemistry. 33: 12852-12859. PMID 7947691 DOI: 10.1021/Bi00209A017 |
0.302 |
|
| 1988 |
Martin ME, Piette J, Yaniv M, Tang WJ, Folk WR. Activation of the polyomavirus enhancer by a murine activator protein 1 (AP1) homolog and two contiguous proteins. Proceedings of the National Academy of Sciences of the United States of America. 85: 5839-43. PMID 2842750 DOI: 10.1073/Pnas.85.16.5839 |
0.351 |
|
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