| Year |
Citation |
Score |
| 2024 |
Gaisina I, Li P, Du R, Cui Q, Dong M, Zhang C, Manicassamy B, Caffrey M, Moore T, Cooper L, Rong L. An orally active entry inhibitor of influenza A viruses protects mice and synergizes with oseltamivir and baloxavir marboxil. Science Advances. 10: eadk9004. PMID 38394202 DOI: 10.1126/sciadv.adk9004 |
0.577 |
|
| 2023 |
Liang CY, Huang I, Han J, Sownthirarajan B, Kulhankova K, Murray NB, Taherzadeh M, Archer-Hartmann S, Pepi L, Manivasagam S, Plung J, Sturtz M, Yu Y, Vogel OA, Kandasamy M, ... ... Manicassamy B, et al. Avian influenza A viruses exhibit plasticity in sialylglycoconjugate receptor usage in human lung cells. Journal of Virology. e0090623. PMID 37843369 DOI: 10.1128/jvi.00906-23 |
0.535 |
|
| 2022 |
Alqarni S, Cooper L, Galvan Achi J, Bott R, Sali VK, Brown A, Santarsiero BD, Krunic A, Manicassamy B, Peet NP, Zhang P, Thatcher GRJ, Gaisina IN, Rong L, Moore TW. Synthesis, Optimization, and Structure-Activity Relationships of Imidazo[1,2-]pyrimidines as Inhibitors of Group 2 Influenza A Viruses. Journal of Medicinal Chemistry. PMID 36260129 DOI: 10.1021/acs.jmedchem.2c01329 |
0.622 |
|
| 2022 |
Zhao X, Lin X, Li P, Chen Z, Zhang C, Manicassamy B, Rong L, Cui Q, Du R. Expanding the tolerance of segmented Influenza A Virus genome using a balance compensation strategy. Plos Pathogens. 18: e1010756. PMID 35926068 DOI: 10.1371/journal.ppat.1010756 |
0.61 |
|
| 2021 |
Malicoat J, Manivasagam S, Zuñiga S, Sola I, McCabe D, Rong L, Perlman S, Enjuanes L, Manicassamy B. Development of a Single-cycle Infectious SARS-CoV-2 Virus Replicon Particle System for use in BSL2 Laboratories. Journal of Virology. JVI0183721. PMID 34851142 DOI: 10.1128/JVI.01837-21 |
0.601 |
|
| 2021 |
Ganti K, Han J, Manicassamy B, Lowen AC. Rab11a mediates cell-cell spread and reassortment of influenza A virus genomes via tunneling nanotubes. Plos Pathogens. 17: e1009321. PMID 34473799 DOI: 10.1371/journal.ppat.1009321 |
0.461 |
|
| 2021 |
Han J, Ganti K, Sali VK, Twigg C, Zhang Y, Manivasagam S, Liang CY, Vogel OA, Huang I, Emmanuel SN, Plung J, Radoshevich L, Perez JT, Lowen AC, Manicassamy B. Host factor Rab11a is critical for efficient assembly of influenza A virus genomic segments. Plos Pathogens. 17: e1009517. PMID 33970958 DOI: 10.1371/journal.ppat.1009517 |
0.374 |
|
| 2020 |
Vogel OA, Han J, Liang CY, Manicassamy S, Perez JT, Manicassamy B. The p150 Isoform of ADAR1 Blocks Sustained RLR signaling and Apoptosis during Influenza Virus Infection. Plos Pathogens. 16: e1008842. PMID 32898178 DOI: 10.1371/Journal.Ppat.1008842 |
0.474 |
|
| 2020 |
Antanasijevic A, Durst MA, Cheng H, Gaisina IN, Perez JT, Manicassamy B, Rong L, Lavie A, Caffrey M. Structure of avian influenza hemagglutinin in complex with a small molecule entry inhibitor. Life Science Alliance. 3. PMID 32611549 DOI: 10.26508/lsa.202000724 |
0.547 |
|
| 2020 |
Hussein AFA, Cheng H, Tundup S, Antanasijevic A, Varhegyi E, Perez J, AbdulRahman EM, Elenany MG, Helal S, Caffrey M, Peet N, Manicassamy B, Rong L. Identification of entry inhibitors with 4-aminopiperidine scaffold targeting group 1 influenza A virus. Antiviral Research. 104782. PMID 32222293 DOI: 10.1016/J.Antiviral.2020.104782 |
0.664 |
|
| 2020 |
Moore JR, Ahmed H, Manicassamy B, Garcia-Sastre A, Handel A, Antia R. Varying Inoculum Dose to Assess the Roles of the Immune Response and Target Cell Depletion by the Pathogen in Control of Acute Viral Infections. Bulletin of Mathematical Biology. 82: 35. PMID 32125535 DOI: 10.1007/S11538-020-00711-4 |
0.381 |
|
| 2020 |
Vogel OA, Manicassamy B. Broadly Protective Strategies Against Influenza Viruses: Universal Vaccines and Therapeutics. Frontiers in Microbiology. 11: 135. PMID 32117155 DOI: 10.3389/Fmicb.2020.00135 |
0.49 |
|
| 2020 |
Kandasamy M, Furlong K, Perez JT, Manicassamy S, Manicassamy B. Suppression of Cytotoxic T Cell Functions and Decreased Levels of Tissue Resident Memory T cell During H5N1 infection. Journal of Virology. PMID 32075925 DOI: 10.1128/Jvi.00057-20 |
0.547 |
|
| 2020 |
Gaisina IN, Peet N, Cheng H, Li P, Du R, Cui Q, Furlong K, Manicassamy B, Caffrey M, Thatcher GR, Rong L. Optimization of 4-aminopiperidines as inhibitors of influenza A viral entry that are synergistic with oseltamivir. Journal of Medicinal Chemistry. PMID 32069052 DOI: 10.1021/Acs.Jmedchem.9B01900 |
0.673 |
|
| 2018 |
Li P, Cui Q, Wang L, Zhao X, Zhang Y, Manicassamy B, Yang Y, Rong L, Du R. A Simple and Robust Approach for Evaluation of Antivirals Using a Recombinant Influenza Virus Expressing Luciferase. Viruses. 10. PMID 29899269 DOI: 10.3390/V10060325 |
0.689 |
|
| 2018 |
Han J, Perez JT, Chen C, Li Y, Benitez A, Kandasamy M, Lee Y, Andrade J, tenOever B, Manicassamy B. Genome-wide CRISPR/Cas9 Screen Identifies Host Factors Essential for Influenza Virus Replication. Cell Reports. 23: 596-607. PMID 29642015 DOI: 10.1016/J.Celrep.2018.03.045 |
0.54 |
|
| 2018 |
Yildiz S, Mazel-Sanchez B, Kandasamy M, Manicassamy B, Schmolke M. Influenza A virus infection impacts systemic microbiota dynamics and causes quantitative enteric dysbiosis. Microbiome. 6: 9. PMID 29321057 DOI: 10.1186/S40168-017-0386-Z |
0.45 |
|
| 2018 |
White KM, Abreu P, Wang H, De Jesus PD, Manicassamy B, García-Sastre A, Chanda SK, DeVita RJ, Shaw ML. Broad Spectrum Inhibitor of Influenza A and B Viruses Targeting the Viral Nucleoprotein. Acs Infectious Diseases. PMID 29268608 DOI: 10.1021/Acsinfecdis.7B00120 |
0.523 |
|
| 2017 |
Schafer AM, Cheng H, Lee C, Du R, Han J, Perez J, Peet N, Manicassamy B, Rong L. Development of Potential Small Molecule Therapeutics for Treatment of Ebola Virus. Current Medicinal Chemistry. PMID 29032747 DOI: 10.2174/0929867324666171010141416 |
0.672 |
|
| 2017 |
Han J, Perez J, Schafer A, Cheng H, Peet N, Rong L, Manicassamy B. Influenza Virus: Small Molecule Therapeutics and Mechanisms of Antiviral. Current Medicinal Chemistry. PMID 28933281 DOI: 10.2174/0929867324666170920165926 |
0.652 |
|
| 2017 |
Tundup S, Kandasamy M, Perez JT, Mena N, Steel J, Nagy T, Albrecht RA, Manicassamy B. Endothelial cell tropism is a determinant of H5N1 pathogenesis in mammalian species. Plos Pathogens. 13: e1006270. PMID 28282445 DOI: 10.1371/Journal.Ppat.1006270 |
0.56 |
|
| 2016 |
Antanasijevic A, Hafeman NJ, Tundup S, Kingsley C, Mishra RK, Rong L, Manicassamy B, Wardrop D, Caffrey M. Stabilization and Improvement of a Promising Influenza Antiviral: Making a PAIN PAINless. Acs Infectious Diseases. 2: 608-615. PMID 27759373 DOI: 10.1021/Acsinfecdis.6B00046 |
0.598 |
|
| 2016 |
Kandasamy M, Suryawanshi A, Tundup S, Perez JT, Schmolke M, Manicassamy S, Manicassamy B. RIG-I Signaling Is Critical for Efficient Polyfunctional T Cell Responses during Influenza Virus Infection. Plos Pathogens. 12: e1005754. PMID 27438481 DOI: 10.1371/Journal.Ppat.1005754 |
0.451 |
|
| 2015 |
Tripathi S, Pohl MO, Zhou Y, Rodriguez-Frandsen A, Wang G, Stein DA, Moulton HM, DeJesus P, Che J, Mulder LC, Yángüez E, Andenmatten D, Pache L, Manicassamy B, Albrecht RA, et al. Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding. Cell Host & Microbe. 18: 723-735. PMID 26651948 DOI: 10.1016/J.Chom.2015.11.002 |
0.541 |
|
| 2015 |
Pisanelli G, Laurent-Rolle M, Manicassamy B, Belicha-Villanueva A, Morrison J, Lozano-Dubernard B, Castro-Peralta F, Iovane G, García-Sastre A. La Piedad Michoacán Mexico Virus V protein antagonizes type I interferon response by binding STAT2 protein and preventing STATs nuclear translocation. Virus Research. PMID 26546155 DOI: 10.1016/J.Virusres.2015.10.027 |
0.397 |
|
| 2015 |
Schoggins JW, MacDuff DA, Imanaka N, Gainey MD, Shrestha B, Eitson JL, Mar KB, Richardson RB, Ratushny AV, Litvak V, Dabelic R, Manicassamy B, Aitchison JD, Aderem A, Elliott RM, et al. Corrigendum: Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity. Nature. 525: 144. PMID 26153856 DOI: 10.1038/Nature14555 |
0.488 |
|
| 2015 |
Roberts KL, Manicassamy B, Lamb RA. Influenza A virus uses intercellular connections to spread to neighboring cells. Journal of Virology. 89: 1537-49. PMID 25428869 DOI: 10.1128/Jvi.03306-14 |
0.547 |
|
| 2014 |
Danzy S, Studdard LR, Manicassamy B, Solorzano A, Marshall N, García-Sastre A, Steel J, Lowen AC. Mutations to PB2 and NP proteins of an avian influenza virus combine to confer efficient growth in primary human respiratory cells. Journal of Virology. 88: 13436-46. PMID 25210184 DOI: 10.1128/Jvi.01093-14 |
0.46 |
|
| 2014 |
Schmolke M, Patel JR, de Castro E, Sánchez-Aparicio MT, Uccellini MB, Miller JC, Manicassamy B, Satoh T, Kawai T, Akira S, Merad M, García-Sastre A. RIG-I detects mRNA of intracellular Salmonella enterica serovar Typhimurium during bacterial infection. Mbio. 5: e01006-14. PMID 24692634 DOI: 10.1128/Mbio.01006-14 |
0.326 |
|
| 2014 |
Schoggins JW, MacDuff DA, Imanaka N, Gainey MD, Shrestha B, Eitson JL, Mar KB, Richardson RB, Ratushny AV, Litvak V, Dabelic R, Manicassamy B, Aitchison JD, Aderem A, Elliott RM, et al. Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity. Nature. 505: 691-5. PMID 24284630 DOI: 10.1038/Nature12862 |
0.492 |
|
| 2013 |
Medina RA, Stertz S, Manicassamy B, Zimmermann P, Sun X, Albrecht RA, Uusi-Kerttula H, Zagordi O, Belshe RB, Frey SE, Tumpey TM, GarcÃa-Sastre A. Glycosylations in the globular head of the hemagglutinin protein modulate the virulence and antigenic properties of the H1N1 influenza viruses. Science Translational Medicine. 5: 187ra70. PMID 23720581 DOI: 10.1126/Scitranslmed.3005996 |
0.543 |
|
| 2013 |
Perez JT, García-Sastre A, Manicassamy B. Insertion of a GFP reporter gene in influenza virus. Current Protocols in Microbiology. Unit 15G.4. PMID 23686828 DOI: 10.1002/9780471729259.Mc15G04S29 |
0.511 |
|
| 2012 |
Hufford MM, Richardson G, Zhou H, Manicassamy B, García-Sastre A, Enelow RI, Braciale TJ. Influenza-infected neutrophils within the infected lungs act as antigen presenting cells for anti-viral CD8(+) T cells. Plos One. 7: e46581. PMID 23056353 DOI: 10.1371/Journal.Pone.0046581 |
0.436 |
|
| 2012 |
Helft J, Manicassamy B, Guermonprez P, Hashimoto D, Silvin A, Agudo J, Brown BD, Schmolke M, Miller JC, Leboeuf M, Murphy KM, García-Sastre A, Merad M. Cross-presenting CD103+ dendritic cells are protected from influenza virus infection. The Journal of Clinical Investigation. 122: 4037-47. PMID 23041628 DOI: 10.1172/Jci60659 |
0.498 |
|
| 2012 |
Ward SE, Kim HS, Komurov K, Mendiratta S, Tsai PL, Schmolke M, Satterly N, Manicassamy B, Forst CV, Roth MG, GarcÃa-Sastre A, Blazewska KM, McKenna CE, Fontoura BM, White MA. Host modulators of H1N1 cytopathogenicity. Plos One. 7: e39284. PMID 22876275 DOI: 10.1371/Journal.Pone.0039284 |
0.582 |
|
| 2012 |
Varga ZT, Grant A, Manicassamy B, Palese P. Influenza virus protein PB1-F2 inhibits the induction of type I interferon by binding to MAVS and decreasing mitochondrial membrane potential. Journal of Virology. 86: 8359-66. PMID 22674996 DOI: 10.1128/Jvi.01122-12 |
0.387 |
|
| 2012 |
Marazzi I, Ho JS, Kim J, Manicassamy B, Dewell S, Albrecht RA, Seibert CW, Schaefer U, Jeffrey KL, Prinjha RK, Lee K, GarcÃa-Sastre A, Roeder RG, Tarakhovsky A. Suppression of the antiviral response by an influenza histone mimic. Nature. 483: 428-33. PMID 22419161 DOI: 10.1038/Nature10892 |
0.587 |
|
| 2012 |
Zhang L, Das P, Schmolke M, Manicassamy B, Wang Y, Deng X, Cai L, Tu BP, Forst CV, Roth MG, Levy DE, GarcÃa-Sastre A, de Brabander J, Phillips MA, Fontoura BM. Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export. The Journal of Cell Biology. 196: 315-26. PMID 22312003 DOI: 10.1083/Jcb.201107058 |
0.47 |
|
| 2011 |
Schmolke M, Manicassamy B, Pena L, Sutton T, Hai R, Varga ZT, Hale BG, Steel J, Pérez DR, García-Sastre A. Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species. Plos Pathogens. 7: e1002186. PMID 21852950 DOI: 10.1371/Journal.Ppat.1002186 |
0.525 |
|
| 2011 |
Bortz E, Westera L, Maamary J, Steel J, Albrecht RA, Manicassamy B, Chase G, Martínez-Sobrido L, Schwemmle M, García-Sastre A. Host- and strain-specific regulation of influenza virus polymerase activity by interacting cellular proteins. Mbio. 2. PMID 21846828 DOI: 10.1128/Mbio.00151-11 |
0.567 |
|
| 2011 |
Wang J, Manicassamy B, Caffrey M, Rong L. Characterization of the receptor-binding domain of Ebola glycoprotein in viral entry. Virologica Sinica. 26: 156-70. PMID 21667336 DOI: 10.1007/S12250-011-3194-9 |
0.747 |
|
| 2010 |
Ye J, Sorrell EM, Cai Y, Shao H, Xu K, Pena L, Hickman D, Song H, Angel M, Medina RA, Manicassamy B, Garcia-Sastre A, Perez DR. Variations in the hemagglutinin of the 2009 H1N1 pandemic virus: potential for strains with altered virulence phenotype? Plos Pathogens. 6: e1001145. PMID 20976194 DOI: 10.1371/Journal.Ppat.1001145 |
0.468 |
|
| 2010 |
Medina RA, Manicassamy B, Stertz S, Seibert CW, Hai R, Belshe RB, Frey SE, Basler CF, Palese P, García-Sastre A. Pandemic 2009 H1N1 vaccine protects against 1918 Spanish influenza virus. Nature Communications. 1: 28. PMID 20975689 DOI: 10.1038/Ncomms1026 |
0.523 |
|
| 2010 |
Manicassamy B, Manicassamy S, Belicha-Villanueva A, Pisanelli G, Pulendran B, García-Sastre A. Analysis of in vivo dynamics of influenza virus infection in mice using a GFP reporter virus. Proceedings of the National Academy of Sciences of the United States of America. 107: 11531-6. PMID 20534532 DOI: 10.1073/Pnas.0914994107 |
0.59 |
|
| 2010 |
Varble A, Chua MA, Perez JT, Manicassamy B, García-Sastre A, tenOever BR. Engineered RNA viral synthesis of microRNAs. Proceedings of the National Academy of Sciences of the United States of America. 107: 11519-24. PMID 20534531 DOI: 10.1073/Pnas.1003115107 |
0.38 |
|
| 2010 |
Hale BG, Steel J, Medina RA, Manicassamy B, Ye J, Hickman D, Hai R, Schmolke M, Lowen AC, Perez DR, García-Sastre A. Inefficient control of host gene expression by the 2009 pandemic H1N1 influenza A virus NS1 protein. Journal of Virology. 84: 6909-22. PMID 20444891 DOI: 10.1128/Jvi.00081-10 |
0.605 |
|
| 2010 |
Hale BG, Steel J, Manicassamy B, Medina RA, Ye J, Hickman D, Lowen AC, Perez DR, García-Sastre A. Mutations in the NS1 C-terminal tail do not enhance replication or virulence of the 2009 pandemic H1N1 influenza A virus. The Journal of General Virology. 91: 1737-42. PMID 20237225 DOI: 10.1099/Vir.0.020925-0 |
0.6 |
|
| 2010 |
Hai R, Schmolke M, Varga ZT, Manicassamy B, Wang TT, Belser JA, Pearce MB, García-Sastre A, Tumpey TM, Palese P. PB1-F2 expression by the 2009 pandemic H1N1 influenza virus has minimal impact on virulence in animal models. Journal of Virology. 84: 4442-50. PMID 20181699 DOI: 10.1128/Jvi.02717-09 |
0.531 |
|
| 2010 |
Manicassamy B, Medina RA, Hai R, Tsibane T, Stertz S, Nistal-Villán E, Palese P, Basler CF, García-Sastre A. Protection of mice against lethal challenge with 2009 H1N1 influenza A virus by 1918-like and classical swine H1N1 based vaccines. Plos Pathogens. 6: e1000745. PMID 20126449 DOI: 10.1371/Journal.Ppat.1000745 |
0.547 |
|
| 2010 |
Tscherne DM, Manicassamy B, García-Sastre A. An enzymatic virus-like particle assay for sensitive detection of virus entry. Journal of Virological Methods. 163: 336-43. PMID 19879300 DOI: 10.1016/J.Jviromet.2009.10.020 |
0.572 |
|
| 2010 |
Martinez O, Johnson J, Manicassamy B, Rong L, Olinger GG, Hensley LE, Basler CF. Zaire Ebola virus entry into human dendritic cells is insensitive to cathepsin L inhibition. Cellular Microbiology. 12: 148-57. PMID 19775255 DOI: 10.1111/J.1462-5822.2009.01385.X |
0.579 |
|
| 2009 |
Jiang H, Wang J, Manicassamy B, Manicassamy S, Caffrey M, Rong L. The Role of the Charged Residues of the GP2 Helical Regions in Ebola Entry(). Virologica Sinica. 24: 121-135. PMID 23227032 DOI: 10.1007/S12250-009-3015-6 |
0.721 |
|
| 2009 |
Manicassamy B, Rong L. Expression of Ebolavirus glycoprotein on the target cells enhances viral entry. Virology Journal. 6: 75. PMID 19505320 DOI: 10.1186/1743-422X-6-75 |
0.651 |
|
| 2008 |
Rothwangl KB, Manicassamy B, Uprichard SL, Rong L. Dissecting the role of putative CD81 binding regions of E2 in mediating HCV entry: putative CD81 binding region 1 is not involved in CD81 binding. Virology Journal. 5: 46. PMID 18355410 DOI: 10.1186/1743-422X-5-46 |
0.526 |
|
| 2007 |
Manicassamy B, Wang J, Rumschlag E, Tymen S, Volchkova V, Volchkov V, Rong L. Characterization of Marburg virus glycoprotein in viral entry. Virology. 358: 79-88. PMID 16989883 DOI: 10.1016/J.Virol.2006.06.041 |
0.755 |
|
| 2005 |
Manicassamy B, Wang J, Jiang H, Rong L. Comprehensive analysis of ebola virus GP1 in viral entry. Journal of Virology. 79: 4793-805. PMID 15795265 DOI: 10.1128/Jvi.79.8.4793-4805.2005 |
0.771 |
|
| 2002 |
Wang QY, Manicassamy B, Yu X, Dolmer K, Gettins PG, Rong L. Characterization of the LDL-A module mutants of Tva, the subgroup A Rous sarcoma virus receptor, and the implications in protein folding. Protein Science : a Publication of the Protein Society. 11: 2596-605. PMID 12381843 DOI: 10.1110/Ps.0219802 |
0.662 |
|
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