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Cassandra N. Spracklen, Ph.D. - Publications

Affiliations: 
2014 Epidemiology University of Iowa, Iowa City, IA 
Area:
Epidemiology, Public Health, Genetics
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27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Yaghootkar H, Zhang Y, Spracklen CN, Karaderi T, Huang LO, Bradfield J, Schurmann C, Fine RS, Preuss MH, Kutalik Z, Wittemans LB, Lu Y, Metz S, Willems SM, Li-Gao R, et al. Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. Diabetes. PMID 32917775 DOI: 10.2337/Db20-0070  0.362
2020 Spracklen CN, Iyengar AK, Vadlamudi S, Raulerson CK, Jackson AU, Brotman SM, Wu Y, Cannon ME, Davis JP, Crain AT, Currin KW, Perrin HJ, Narisu N, Stringham HM, Fuchsberger C, et al. Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences. Plos Genetics. 16: e1009019. PMID 32915782 DOI: 10.1371/Journal.Pgen.1009019  0.366
2020 Vuckovic D, Bao EL, Akbari P, Lareau CA, Mousas A, Jiang T, Chen MH, Raffield LM, Tardaguila M, Huffman JE, Ritchie SC, Megy K, Ponstingl H, Penkett CJ, Albers PK, ... ... Spracklen CN, et al. The Polygenic and Monogenic Basis of Blood Traits and Diseases. Cell. 182: 1214-1231.e11. PMID 32888494 DOI: 10.1016/J.Cell.2020.08.008  0.343
2020 Chen MH, Raffield LM, Mousas A, Sakaue S, Huffman JE, Moscati A, Trivedi B, Jiang T, Akbari P, Vuckovic D, Bao EL, Zhong X, Manansala R, Laplante V, Chen M, ... ... Spracklen CN, et al. Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Cell. 182: 1198-1213.e14. PMID 32888493 DOI: 10.1016/J.Cell.2020.06.045  0.372
2020 Spracklen CN, Horikoshi M, Kim YJ, Lin K, Bragg F, Moon S, Suzuki K, Tam CHT, Tabara Y, Kwak SH, Takeuchi F, Long J, Lim VJY, Chai JF, Chen CH, et al. Identification of type 2 diabetes loci in 433,540 East Asian individuals. Nature. PMID 32499647 DOI: 10.1038/S41586-020-2263-3  0.403
2019 Raffield LM, Iyengar AK, Wang B, Gaynor SM, Spracklen CN, Zhong X, Kowalski MH, Salimi S, Polfus LM, Benjamin EJ, Bis JC, Bowler R, Cade BE, Choi WJ, Comellas AP, et al. Allelic Heterogeneity at the CRP Locus Identified by Whole-Genome Sequencing in Multi-ancestry Cohorts. American Journal of Human Genetics. PMID 31883642 DOI: 10.1016/J.Ajhg.2019.12.002  0.37
2019 Clark DW, Okada Y, Moore KHS, Mason D, Pirastu N, Gandin I, Mattsson H, Barnes CLK, Lin K, Zhao JH, Deelen P, Rohde R, Schurmann C, Guo X, Giulianini F, ... ... Spracklen CN, et al. Associations of autozygosity with a broad range of human phenotypes. Nature Communications. 10: 4957. PMID 31673082 DOI: 10.1038/S41467-019-12283-6  0.315
2019 Tin A, Marten J, Halperin Kuhns VL, Li Y, Wuttke M, Kirsten H, Sieber KB, Qiu C, Gorski M, Yu Z, Giri A, Sveinbjornsson G, Li M, Chu AY, Hoppmann A, ... ... Spracklen CN, et al. Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. Nature Genetics. PMID 31578528 DOI: 10.1038/S41588-019-0504-X  0.367
2019 Raulerson CK, Ko A, Kidd JC, Currin KW, Brotman SM, Cannon ME, Wu Y, Spracklen CN, Jackson AU, Stringham HM, Welch RP, Fuchsberger C, Locke AE, Narisu N, Lusis AJ, et al. Adipose Tissue Gene Expression Associations Reveal Hundreds of Candidate Genes for Cardiometabolic Traits. American Journal of Human Genetics. PMID 31564431 DOI: 10.1016/J.Ajhg.2019.09.001  0.378
2019 Spracklen CN, Karaderi T, Yaghootkar H, Schurmann C, Fine RS, Kutalik Z, Preuss MH, Lu Y, Wittemans LBL, Adair LS, Allison M, Amin N, Auer PL, Bartz TM, Blüher M, et al. Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology. American Journal of Human Genetics. PMID 31178129 DOI: 10.1016/J.Ajhg.2019.05.002  0.413
2019 Zhong W, Spracklen CN, Mohlke KL, Zheng X, Fine J, Li Y. Multi-SNP mediation intersection-union test. Bioinformatics (Oxford, England). PMID 31099385 DOI: 10.1093/Bioinformatics/Btz285  0.315
2018 Dagle JM, Ryckman KK, Spracklen CN, Momany AM, Cotten CM, Levy J, Page GP, Bell EF, Carlo WA, Shankaran S, Goldberg RN, Ehrenkranz RA, Tyson JE, Stoll BJ, Murray JC, et al. Genetic variants associated with patent ductus arteriosus in extremely preterm infants. Journal of Perinatology : Official Journal of the California Perinatal Association. PMID 30518802 DOI: 10.1038/S41372-018-0285-6  0.336
2018 Takeuchi F, Akiyama M, Matoba N, Katsuya T, Nakatochi M, Tabara Y, Narita A, Saw WY, Moon S, Spracklen CN, Chai JF, Kim YJ, Zhang L, Wang C, Li H, et al. Interethnic analyses of blood pressure loci in populations of East Asian and European descent. Nature Communications. 9: 5052. PMID 30487518 DOI: 10.1038/S41467-018-07345-0  0.395
2018 Spracklen CN, Shi J, Vadlamudi S, Wu Y, Zou M, Raulerson CK, Davis JP, Zeynalzadeh M, Jackson K, Yuan W, Wang H, Shou W, Wang Y, Luo J, Lange LA, et al. Identification and functional analysis of glycemic trait loci in the China Health and Nutrition Survey. Plos Genetics. 14: e1007275. PMID 29621232 DOI: 10.1371/Journal.Pgen.1007275  0.358
2017 Lu X, Peloso GM, Liu DJ, Wu Y, Zhang H, Zhou W, Li J, Tang CS, Dorajoo R, Li H, Long J, Guo X, Xu M, Spracklen CN, Chen Y, et al. Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease. Nature Genetics. PMID 29083407 DOI: 10.1038/Ng.3978  0.401
2017 Spracklen CN, Chen P, Kim YJ, Wang X, Cai H, Li S, Long J, Wu Y, Wang YX, Takeuchi F, Wu JY, Jung KJ, Hu C, Akiyama K, Zhang Y, et al. Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels. Human Molecular Genetics. PMID 28334899 DOI: 10.1093/Hmg/Ddx062  0.368
2016 Spracklen CN, Smith CJ, Saftlas AF, Triche EW, Bjonnes A, Keating BJ, Saxena R, Breheny PJ, Dewan AT, Robinson JG, Hoh J, Ryckman KK. Genetic predisposition to elevated levels of C-reactive protein is associated with a decreased risk for preeclampsia. Hypertension in Pregnancy. 1-10. PMID 27657194 DOI: 10.1080/10641955.2016.1223303  0.347
2016 Donovan BM, Spracklen CN, Schweizer ML, Ryckman KK, Saftlas AF. Intimate partner violence during pregnancy and the risk for adverse infant outcomes: a systematic review and meta-analysis. Bjog : An International Journal of Obstetrics and Gynaecology. 123: 1289-99. PMID 26956568 DOI: 10.1111/1471-0528.13928  0.325
2015 Smith CJ, Saftlas AF, Spracklen CN, Triche EW, Bjonnes A, Keating B, Saxena R, Breheny PJ, Dewan AT, Robinson JG, Hoh J, Ryckman KK. Genetic Risk Score for Essential Hypertension and Risk of Preeclampsia. American Journal of Hypertension. PMID 26002928 DOI: 10.1093/Ajh/Hpv069  0.34
2015 Ryckman KK, Spracklen CN, Smith CJ, Robinson JG, Saftlas AF. Maternal lipid levels during pregnancy and gestational diabetes: a systematic review and meta-analysis. Bjog : An International Journal of Obstetrics and Gynaecology. 122: 643-51. PMID 25612005 DOI: 10.1111/1471-0528.13261  0.312
2015 Spracklen CN, Saftlas AF, Triche EW, Bjonnes A, Keating B, Saxena R, Breheny PJ, Dewan AT, Robinson JG, Hoh J, Ryckman KK. Genetic Predisposition to Dyslipidemia and Risk of Preeclampsia. American Journal of Hypertension. 28: 915-23. PMID 25523295 DOI: 10.1093/Ajh/Hpu242  0.376
2015 Fuller TD, Spracklen CN, Ryckman KK, Knake LA, Busch TD, Momany AM, Murray JC, Dagle JM. Genetic variation in CYB5R3 is associated with methemoglobin levels in preterm infants receiving nitric oxide therapy. Pediatric Research. 77: 472-6. PMID 25521918 DOI: 10.1038/Pr.2014.206  0.315
2014 Spracklen CN, Wallace RB, Sealy-Jefferson S, Robinson JG, Freudenheim JL, Wellons MF, Saftlas AF, Snetselaar LG, Manson JE, Hou L, Qi L, Chlebowski RT, Ryckman KK. Birth weight and subsequent risk of cancer. Cancer Epidemiology. 38: 538-43. PMID 25096278 DOI: 10.1016/J.Canep.2014.07.004  0.312
2014 Spracklen CN, Smith CJ, Saftlas AF, Robinson JG, Ryckman KK. Maternal hyperlipidemia and the risk of preeclampsia: a meta-analysis. American Journal of Epidemiology. 180: 346-58. PMID 24989239 DOI: 10.1093/Aje/Kwu145  0.334
2014 Ryckman KK, Spracklen CN, Dagle JM, Murray JC. Maternal factors and complications of preterm birth associated with neonatal thyroid stimulating hormone. Journal of Pediatric Endocrinology & Metabolism : Jpem. 27: 929-38. PMID 24854527 DOI: 10.1515/Jpem-2013-0366  0.307
2014 Ryckman KK, Rillamas-Sun E, Spracklen CN, Wallace RB, Garcia L, Tylavsky FA, Howard BV, Liu S, Song Y, LeBlanc ES, White MV, Parikh NI, Robinson JG. Ethnic differences in the relationship between birth weight and type 2 diabetes mellitus in postmenopausal women. Diabetes & Metabolism. 40: 379-85. PMID 24751988 DOI: 10.1016/J.Diabet.2014.03.003  0.326
2013 Spracklen CN, Harland KK, Stegmann BJ, Saftlas AF. Cervical surgery for cervical intraepithelial neoplasia and prolonged time to conception of a live birth: a case-control study. Bjog : An International Journal of Obstetrics and Gynaecology. 120: 960-5. PMID 23489374 DOI: 10.1111/1471-0528.12209  0.307
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