James E. Cassat, Ph.D. - Publications

Affiliations: 
2006 University of Arkansas for Medical Sciences, United States 
Area:
Microbiology Biology, Pathology

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Paul S, Todd OA, Eichelberger KR, Tkaczyk C, Sellman BR, Noverr MC, Cassat JE, Fidel PL, Peters BM. A fungal metabolic regulator underlies infectious synergism during - aureus intra-abdominal co-infection. Biorxiv : the Preprint Server For Biology. PMID 38405692 DOI: 10.1101/2024.02.15.580531  0.326
2023 Butrico CE, Klopfenstein N, Green ER, Johnson JR, Peck SH, Ibberson CB, Serezani CH, Cassat JE. Hyperglycemia Increases Severity of Staphylococcus aureus Osteomyelitis and Influences Bacterial Genes Required for Survival in Bone. Infection and Immunity. e0052922. PMID 36877063 DOI: 10.1128/iai.00529-22  0.405
2022 Gehrke AE, Mendoza-Bertelli A, Ledo C, Gonzalez CD, Noto Llana M, Blanco C, Sordelli DO, Putman NE, Cassat JE, Delpino MV, Gómez MI. Neutralization of Staphylococcus aureus Protein A Prevents Exacerbated Osteoclast Activity and Bone Loss during Osteomyelitis. Antimicrobial Agents and Chemotherapy. e0114022. PMID 36533935 DOI: 10.1128/aac.01140-22  0.434
2022 Moriarty TF, Metsemakers WJ, Morgenstern M, Hofstee MI, Vallejo Diaz A, Cassat JE, Wildemann B, Depypere M, Schwarz EM, Richards RG. Fracture-related infection. Nature Reviews. Disease Primers. 8: 67. PMID 36266296 DOI: 10.1038/s41572-022-00396-0  0.325
2022 Petronglo JR, Putnam NE, Ford CA, Cruz-Victorio V, Curry JM, Butrico CE, Fulbright LE, Johnson JR, Peck SH, Fatah SR, Cassat JE. Context-Dependent Roles for Toll-Like Receptors 2 and 9 in the Pathogenesis of Staphylococcus aureus Osteomyelitis. Infection and Immunity. e0041722. PMID 36226943 DOI: 10.1128/iai.00417-22  0.405
2022 Ford CA, Hurford IM, Fulbright LE, Curry JM, Peek CT, Spoonmore TJ, Cruz Victorio V, Johnson JR, Peck SH, Cassat JE. Loss of alters trabecular bone loss during osteomyelitis in a cell-specific manner. Frontiers in Cellular and Infection Microbiology. 12: 985467. PMID 36204648 DOI: 10.3389/fcimb.2022.985467  0.439
2022 Peek CT, Ford CA, Eichelberger KR, Jacobse J, Torres TP, Maseda D, Latour YL, Piazuelo MB, Johnson JR, Byndloss MX, Wilson KT, Rathmell JC, Goettel JA, Cassat JE. Intestinal inflammation promotes MDL-1 osteoclast precursor expansion to trigger osteoclastogenesis and bone loss. Cellular and Molecular Gastroenterology and Hepatology. PMID 35835390 DOI: 10.1016/j.jcmgh.2022.07.002  0.301
2021 Ford CA, Cassat JE. Measurement of Osteoblast Cytotoxicity Induced by S. aureus Secreted Toxins. Methods in Molecular Biology (Clifton, N.J.). 2341: 141-152. PMID 34264470 DOI: 10.1007/978-1-0716-1550-8_17  0.44
2021 Roper PM, Eichelberger KR, Cox L, O'Connor L, Shao C, Ford CA, Fritz SA, Cassat JE, Veis DJ. Contemporary clinical isolates of from pediatric osteomyelitis patients display unique characteristics in a mouse model of hematogenous osteomyelitis. Infection and Immunity. IAI0018021. PMID 34097469 DOI: 10.1128/IAI.00180-21  0.462
2021 Veis DJ, Cassat JE. Infectious Osteomyelitis: Marrying Bone Biology and Microbiology to Shed New Light on a Persistent Clinical Challenge. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 33740314 DOI: 10.1002/jbmr.4279  0.444
2021 Klopfenstein N, Cassat JE, Monteith A, Miller A, Drury S, Skaar E, Serezani CH. Murine Models for Staphylococcal Infection. Current Protocols. 1: e52. PMID 33656290 DOI: 10.1002/cpz1.52  0.342
2021 Gimza BD, Cassat JE. Mechanisms of Antibiotic Failure During Osteomyelitis. Frontiers in Immunology. 12: 638085. PMID 33643322 DOI: 10.3389/fimmu.2021.638085  0.476
2020 Ford CA, Hurford IM, Cassat JE. Antivirulence Strategies for the Treatment of Infections: A Mini Review. Frontiers in Microbiology. 11: 632706. PMID 33519793 DOI: 10.3389/fmicb.2020.632706  0.305
2020 Ford CA, Spoonmore TJ, Gupta MK, Duvall CL, Guelcher SA, Cassat JE. Diflunisal-loaded poly(propylene sulfide) nanoparticles decrease S. aureus-mediated bone destruction during osteomyelitis. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 33300149 DOI: 10.1002/jor.24948  0.372
2020 Butrico CE, Cassat JE. Quorum Sensing and Toxin Production in Osteomyelitis: Pathogenesis and Paradox. Toxins. 12. PMID 32806558 DOI: 10.3390/Toxins12080516  0.529
2020 Potter AD, Butrico CE, Ford CA, Curry JM, Trenary IA, Tummarakota SS, Hendrix AS, Young JD, Cassat JE. Host nutrient milieu drives an essential role for aspartate biosynthesis during invasive infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 32414924 DOI: 10.1073/Pnas.1922211117  0.452
2020 Spoonmore TJ, Ford CA, Curry JM, Guelcher SA, Cassat JE. Concurrent local delivery of diflunisal limits bone destruction but fails to improve systemic vancomycin efficacy during osteomyelitis. Antimicrobial Agents and Chemotherapy. PMID 32340992 DOI: 10.1128/Aac.00182-20  0.524
2020 Urish KL, Cassat JE. Osteomyelitis: Bone, Bugs, and Surgery. Infection and Immunity. PMID 32094258 DOI: 10.1128/Iai.00932-19  0.542
2020 Peek CT, Ibberson CB, Cassat JE. Identification of Virulence Determinants During Host-Pathogen Interaction Using Tn-Seq Technology. Methods in Molecular Biology (Clifton, N.J.). 2069: 155-175. PMID 31523773 DOI: 10.1007/978-1-4939-9849-4_12  0.359
2019 Krauss JL, Roper PM, Ballard A, Shih CC, Fitzpatrick JAJ, Cassat JE, Ng PY, Pavlos NJ, Veis DJ. Staphylococcus aureus Infects Osteoclasts and Replicates Intracellularly. Mbio. 10. PMID 31615966 DOI: 10.1128/Mbio.02447-19  0.519
2019 Putnam NE, Fulbright LE, Curry JM, Ford CA, Petronglo JR, Hendrix AS, Cassat JE. MyD88 and IL-1R signaling drive antibacterial immunity and osteoclast-driven bone loss during Staphylococcus aureus osteomyelitis. Plos Pathogens. 15: e1007744. PMID 30978245 DOI: 10.1371/Journal.Ppat.1007744  0.495
2018 Brandt SL, Putnam NE, Cassat JE, Serezani CH. Innate Immunity to : Evolving Paradigms in Soft Tissue and Invasive Infections. Journal of Immunology (Baltimore, Md. : 1950). 200: 3871-3880. PMID 29866769 DOI: 10.4049/Jimmunol.1701574  0.405
2018 Buenrostro D, Kwakwa KA, Putnam NE, Merkel AR, Johnson JR, Cassat JE, Sterling JA. Early TGF-β inhibition in mice reduces the incidence of breast cancer induced bone disease in a myeloid dependent manner. Bone. PMID 29753718 DOI: 10.1016/J.Bone.2018.05.008  0.397
2017 Ford CA, Cassat JE. Advances in the local and targeted delivery of anti-infective agents for management of osteomyelitis. Expert Review of Anti-Infective Therapy. PMID 28837368 DOI: 10.1080/14787210.2017.1372192  0.44
2017 Thomsen IP, Sapparapu G, James DB, Cassat JE, Nagarsheth M, Kose N, Putnam N, Boguslawski KM, Jones LS, Wood JB, Creech CB, Torres VJ, Crowe JE. Monoclonal antibodies against the Staphylococcus aureus bicomponent leukotoxin AB (LukAB) isolated following invasive human infection reveal diverse binding and modes of action. The Journal of Infectious Diseases. PMID 28186295 DOI: 10.1093/Infdis/Jix071  0.367
2016 Bertelli AM, Delpino MV, Lattar S, Giai C, Llana MN, Sanjuan N, Cassat JE, Sordelli D, Gomez MI. Staphylococcus aureus protein A enhances osteoclastogenesis via TNFR1 and EGFR signaling. Biochimica Et Biophysica Acta. PMID 27475257 DOI: 10.1016/J.Bbadis.2016.07.016  0.483
2016 Loughran AJ, Gaddy D, Beenken KE, Meeker DG, Morello R, Zhao H, Byrum SD, Tackett AJ, Cassat JE, Smeltzer MS. Impact of sarA and phenol-soluble modulins in the pathogenesis of osteomyelitis in diverse clinical isolates of Staphylococcus aureus. Infection and Immunity. PMID 27354444 DOI: 10.1128/Iai.00152-16  0.734
2016 Hendrix AS, Spoonmore TJ, Wilde AD, Putnam NE, Hammer ND, Snyder DJ, Guelcher SA, Skaar EP, Cassat JE. Repurposing the nonsteroidal anti-inflammatory drug diflunisal as an osteoprotective, anti-virulence therapy for Staphylococcus aureus osteomyelitis. Antimicrobial Agents and Chemotherapy. PMID 27324764 DOI: 10.1128/Aac.00834-16  0.552
2015 Wilde AD, Snyder DJ, Putnam NE, Valentino MD, Hammer ND, Lonergan ZR, Hinger SA, Aysanoa EE, Blanchard C, Dunman PM, Wasserman GA, Chen J, Shopsin B, Gilmore MS, Skaar EP, ... Cassat JE, et al. Bacterial Hypoxic Responses Revealed as Critical Determinants of the Host-Pathogen Outcome by TnSeq Analysis of Staphylococcus aureus Invasive Infection. Plos Pathogens. 11: e1005341. PMID 26684646 DOI: 10.1371/Journal.Ppat.1005341  0.524
2014 Hammer ND, Cassat JE, Noto MJ, Lojek LJ, Chadha AD, Schmitz JE, Creech CB, Skaar EP. Inter- and intraspecies metabolite exchange promotes virulence of antibiotic-resistant Staphylococcus aureus. Cell Host & Microbe. 16: 531-7. PMID 25299336 DOI: 10.1016/J.Chom.2014.09.002  0.411
2014 Cassat JE, Smeltzer MS, Lee CY. Investigation of biofilm formation in clinical isolates of Staphylococcus aureus. Methods in Molecular Biology (Clifton, N.J.). 1085: 195-211. PMID 24085698 DOI: 10.1007/978-1-62703-664-1_12  0.618
2013 Cassat JE, Skaar EP. Recent advances in experimental models of osteomyelitis. Expert Review of Anti-Infective Therapy. 11: 1263-5. PMID 24215241 DOI: 10.1586/14787210.2013.858600  0.303
2013 Hammer ND, Reniere ML, Cassat JE, Zhang Y, Hirsch AO, Hood MI, Skaar EP. Two heme-dependent terminal oxidases power Staphylococcus aureus organ-specific colonization of the vertebrate host Mbio. 4. PMID 23900169 DOI: 10.1128/Mbio.00241-13  0.438
2013 Attia AS, Cassat JE, Aranmolate SO, Zimmerman LJ, Boyd KL, Skaar EP. Analysis of the Staphylococcus aureus abscess proteome identifies antimicrobial host proteins and bacterial stress responses at the host-pathogen interface. Pathogens and Disease. PMID 23847107 DOI: 10.1111/2049-632X.12063  0.402
2013 Cassat JE, Hammer ND, Campbell JP, Benson MA, Perrien DS, Mrak LN, Smeltzer MS, Torres VJ, Skaar EP. A secreted bacterial protease tailors the Staphylococcus aureus virulence repertoire to modulate bone remodeling during osteomyelitis. Cell Host & Microbe. 13: 759-72. PMID 23768499 DOI: 10.1016/J.Chom.2013.05.003  0.646
2012 Cassat JE, Skaar EP. Metal ion acquisition in Staphylococcus aureus: overcoming nutritional immunity. Seminars in Immunopathology. 34: 215-35. PMID 22048835 DOI: 10.1007/S00281-011-0294-4  0.328
2008 Tsang LH, Cassat JE, Shaw LN, Beenken KE, Smeltzer MS. Factors contributing to the biofilm-deficient phenotype of Staphylococcus aureus sarA mutants. Plos One. 3: e3361. PMID 18846215 DOI: 10.1371/Journal.Pone.0003361  0.697
2008 Stenz L, François P, Fischer A, Huyghe A, Tangomo M, Hernandez D, Cassat J, Linder P, Schrenzel J. Impact of oleic acid (cis-9-octadecenoic acid) on bacterial viability and biofilm production in Staphylococcus aureus. Fems Microbiology Letters. 287: 149-55. PMID 18754790 DOI: 10.1111/J.1574-6968.2008.01316.X  0.452
2007 Cassat JE, Lee CY, Smeltzer MS. Investigation of biofilm formation in clinical isolates of Staphylococcus aureus. Methods in Molecular Biology (Clifton, N.J.). 391: 127-44. PMID 18025674 DOI: 10.1007/978-1-59745-468-1_10  0.635
2007 Rice KC, Mann EE, Endres JL, Weiss EC, Cassat JE, Smeltzer MS, Bayles KW. The cidA murein hydrolase regulator contributes to DNA release and biofilm development in Staphylococcus aureus. Proceedings of the National Academy of Sciences of the United States of America. 104: 8113-8. PMID 17452642 DOI: 10.1073/Pnas.0610226104  0.622
2006 Cassat J, Dunman PM, Murphy E, Projan SJ, Beenken KE, Palm KJ, Yang SJ, Rice KC, Bayles KW, Smeltzer MS. Transcriptional profiling of a Staphylococcus aureus clinical isolate and its isogenic agr and sarA mutants reveals global differences in comparison to the laboratory strain RN6390. Microbiology (Reading, England). 152: 3075-90. PMID 17005987 DOI: 10.1099/Mic.0.29033-0  0.711
2005 Cassat JE, Dunman PM, McAleese F, Murphy E, Projan SJ, Smeltzer MS. Comparative genomics of Staphylococcus aureus musculoskeletal isolates. Journal of Bacteriology. 187: 576-92. PMID 15629929 DOI: 10.1128/Jb.187.2.576-592.2005  0.578
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