| Year |
Citation |
Score |
| 2022 |
Rezvani K, WuDunn D, Hunter AK, Aspelund MT. Leveraging light chain binding avidity for control of mispaired byproducts during production of asymmetric bispecific antibodies. Journal of Chromatography. A. 1683: 463533. PMID 36195004 DOI: 10.1016/j.chroma.2022.463533 |
0.32 |
|
| 2022 |
Luo H, Du Q, Qian C, Mlynarczyk M, Pabst TM, Damschroder M, Hunter AK, Wang WK. Formation of transient highly-charged mAb clusters strengthens interactions with host cell proteins and results in poor clearance of host cell proteins by protein A chromatography. Journal of Chromatography. A. 1679: 463385. PMID 35933770 DOI: 10.1016/j.chroma.2022.463385 |
0.745 |
|
| 2021 |
Kimerer LK, Pabst TM, Hunter AK, Carta G. Role of configurational flexibility on the adsorption kinetics of bivalent bispecific antibodies on porous cation exchange resins. Journal of Chromatography. A. 1655: 462479. PMID 34461348 DOI: 10.1016/j.chroma.2021.462479 |
0.791 |
|
| 2021 |
Kimerer LK, Niu B, Pabst TM, Zhai W, Hunter AK, Carta G. Chromatographic and adsorptive behavior of a bivalent bispecific antibody and associated fragments. Journal of Chromatography. A. 1648: 462181. PMID 33989897 DOI: 10.1016/j.chroma.2021.462181 |
0.807 |
|
| 2020 |
Kimerer LK, Pabst TM, Hunter AK, Carta G. Chromatographic behavior of bivalent bispecific antibodies on hydrophobic interaction chromatography columns. Journal of Chromatography. A. 460836. PMID 31973931 DOI: 10.1016/J.Chroma.2019.460836 |
0.797 |
|
| 2019 |
Kittinger C, Barnes A, Hunter A, Machiesky L, Phipps S, Shannon A, Stadelman R, Wilson S, O'Connor E. A high yielding IFNAR1 ECD mammalian expression process for use in autoimmune disease drug development. Protein Expression and Purification. 105528. PMID 31689498 DOI: 10.1016/J.Pep.2019.105528 |
0.325 |
|
| 2019 |
Kimerer LK, Pabst TM, Hunter AK, Carta G. Chromatographic behavior of bivalent bispecific antibodies on cation exchange columns. I. Experimental observations and phenomenological model. Journal of Chromatography. A. PMID 31056270 DOI: 10.1016/J.Chroma.2019.04.012 |
0.802 |
|
| 2019 |
Kimerer LK, Pabst TM, Hunter AK, Carta G. Chromatographic behavior of bivalent bispecific antibodies on cation exchange columns. II. Biomolecular perspectives. Journal of Chromatography. A. PMID 31054833 DOI: 10.1016/J.Chroma.2019.04.013 |
0.785 |
|
| 2019 |
Du Q, Damschroder M, Pabst TM, Hunter AK, Wang WK, Luo H. Process optimization and protein engineering mitigated manufacturing challenges of a monoclonal antibody with liquid-liquid phase separation issue by disrupting inter-molecule electrostatic interactions. Mabs. PMID 30913985 DOI: 10.1080/19420862.2019.1599634 |
0.76 |
|
| 2018 |
Cao M, Mulagapati SHR, Vemulapalli B, Wang J, Saveliev SV, Urh M, Hunter A, Liu D. Characterization and quantification of succinimide using peptide mapping under low-pH conditions and hydrophobic interaction chromatography. Analytical Biochemistry. 566: 151-159. PMID 30503708 DOI: 10.1016/J.Ab.2018.11.021 |
0.391 |
|
| 2018 |
Luo H, Tie L, Cao M, Hunter AK, Pabst TM, Du J, Field R, Li Y, Wang WK. Cathepsin L Causes Proteolytic Cleavage of CHO Expressed Proteins During Processing and Storage: Identification, Characterization, and Mitigation. Biotechnology Progress. PMID 30320962 DOI: 10.1002/Btpr.2732 |
0.745 |
|
| 2018 |
Andrade C, Arnold L, Motabar D, Aspelund M, Tang A, Hunter A, Chung WK. An Integrated Approach to Aggregate Control for Therapeutic Bispecific Antibodies Using an Improved Three Column mAb Platform-Like Purification Process. Biotechnology Progress. PMID 30298991 DOI: 10.1002/Btpr.2720 |
0.485 |
|
| 2018 |
Wang C, Vemulapalli B, Cao M, Gadre D, Wang J, Hunter A, Wang X, Liu D. A systematic approach for analysis and characterization of mispairing in bispecific antibodies with asymmetric architecture. Mabs. PMID 30153083 DOI: 10.1080/19420862.2018.1511198 |
0.395 |
|
| 2018 |
Cao M, Wang C, Chung WK, Motabar D, Wang J, Christian E, Lin S, Hunter A, Wang X, Liu D. Characterization and analysis of scFv-IgG bispecific antibody size variants. Mabs. PMID 30130449 DOI: 10.1080/19420862.2018.1505398 |
0.37 |
|
| 2018 |
Creasy A, Reck J, Pabst T, Hunter A, Barker G, Carta G. Systematic Interpolation Method Predicts Antibody Monomer-Dimer Separation by Gradient Elution Chromatography at High Protein Loads. Biotechnology Journal. e1800132. PMID 29809318 DOI: 10.1002/Biot.201800132 |
0.804 |
|
| 2018 |
Pabst TM, Thai J, Hunter AK. Evaluation of recent Protein A stationary phase innovations for capture of biotherapeutics. Journal of Chromatography. A. PMID 29685337 DOI: 10.1016/J.Chroma.2018.03.060 |
0.786 |
|
| 2017 |
Reck JM, Pabst TM, Hunter AK, Carta G. Separation of antibody monomer-dimer mixtures by frontal analysis. Journal of Chromatography. A. PMID 28420529 DOI: 10.1016/J.Chroma.2017.04.014 |
0.801 |
|
| 2017 |
Luo H, Lee N, Wang X, Li Y, Schmelzer A, Hunter AK, Pabst T, Wang WK. Liquid-liquid phase separation causes high turbidity and pressure during low pH elution process in Protein A chromatography. Journal of Chromatography. A. PMID 28159365 DOI: 10.1016/J.Chroma.2017.01.067 |
0.777 |
|
| 2016 |
Pabst TM, Wendeler M, Wang X, Bezemer S, Hermans P, Hunter AK. Camelid VHH affinity ligands enable separation of closely related biopharmaceuticals. Biotechnology Journal. PMID 27677057 DOI: 10.1002/Biot.201600357 |
0.763 |
|
| 2015 |
Reck JM, Pabst TM, Hunter AK, Wang X, Carta G. Adsorption equilibrium and kinetics of monomer-dimer monoclonal antibody mixtures on a cation exchange resin. Journal of Chromatography. A. 1402: 46-59. PMID 26028510 DOI: 10.1016/J.Chroma.2015.05.007 |
0.802 |
|
| 2014 |
Pabst TM, Palmgren R, Forss A, Vasic J, Fonseca M, Thompson C, Wang WK, Wang X, Hunter AK. Engineering of novel Staphylococcal Protein A ligands to enable milder elution pH and high dynamic binding capacity. Journal of Chromatography. A. 1362: 180-5. PMID 25193170 DOI: 10.1016/J.Chroma.2014.08.046 |
0.759 |
|
| 2014 |
Linke T, Aspelund MT, Thompson C, Xi G, Fulton A, Wendeler M, Pabst TM, Wang X, Wang WK, Ram K, Hunter AK. Development and scale-up of a commercial fed batch refolding process for an anti-CD22 two chain immunotoxin. Biotechnology Progress. 30: 1380-9. PMID 25139260 DOI: 10.1002/Btpr.1983 |
0.714 |
|
| 2014 |
Wendeler M, Pabst TM, Wang J, Strouse RJ, Wang X, Hunter AK. Process-scale purification and analytical characterization of highly gamma-carboxylated recombinant human prothrombin. Journal of Chromatography. A. 1325: 171-8. PMID 24369997 DOI: 10.1016/J.Chroma.2013.12.024 |
0.725 |
|
| 2014 |
Maurer RW, Hunter AK, Robinson AS, Roberts CJ. Aggregates of α-chymotrypsinogen anneal to access more stable states. Biotechnology and Bioengineering. 111: 782-91. PMID 24122552 DOI: 10.1002/Bit.25129 |
0.335 |
|
| 2013 |
Maurer RW, Hunter AK, Wang X, Wang WK, Robinson AS, Roberts CJ. Folding and aggregation of a multi-domain engineered immunotoxin Biochemical Engineering Journal. 81: 8-14. DOI: 10.1016/J.Bej.2013.09.015 |
0.385 |
|
| 2012 |
Linke T, Feng J, Yu K, Kim HJ, Wei Z, Wang Y, Wang WK, Hunter AK. Process scale separation of an anti-CD22 immunotoxin charge variant. Journal of Chromatography. A. 1260: 120-5. PMID 22980642 DOI: 10.1016/J.Chroma.2012.08.061 |
0.384 |
|
| 2010 |
Caparon MH, Rust KJ, Hunter AK, McLaughlin JK, Thomas KE, Herberg JT, Shell RE, Lanter PB, Bishop BF, Dufield RL, Wang X, Ho SV. Integrated solution to purification challenges in the manufacture of a soluble recombinant protein in E. coli. Biotechnology and Bioengineering. 105: 239-49. PMID 19777583 DOI: 10.1002/Bit.22542 |
0.364 |
|
| 2009 |
Pabst TM, Suda EJ, Thomas KE, Mensah P, Ramasubramanyan N, Gustafson ME, Hunter AK. Binding and elution behavior of proteins on strong cation exchangers. Journal of Chromatography. A. 1216: 7950-6. PMID 19815222 DOI: 10.1016/J.Chroma.2009.09.040 |
0.785 |
|
| 2009 |
Suda EJ, Thomas KE, Pabst TM, Mensah P, Ramasubramanyan N, Gustafson ME, Hunter AK. Comparison of agarose and dextran-grafted agarose strong ion exchangers for the separation of protein aggregates. Journal of Chromatography. A. 1216: 5256-64. PMID 19497581 DOI: 10.1016/J.Chroma.2009.05.021 |
0.767 |
|
| 2009 |
Wang X, Hunter AK, Mozier NM. Host cell proteins in biologics development: Identification, quantitation and risk assessment. Biotechnology and Bioengineering. 103: 446-58. PMID 19388135 DOI: 10.1002/Bit.22304 |
0.326 |
|
| 2009 |
Hunter AK, Wang X, Suda EJ, Herberg JT, Shell RE, Thomas KE, Dufield RL, Gustafson ME, Mozier NM, Ho SV. Separation of product associating E. coli host cell proteins OppA and DppA from recombinant apolipoprotein A-I(Milano) in an industrial HIC unit operation. Biotechnology Progress. 25: 446-53. PMID 19291803 DOI: 10.1002/Btpr.106 |
0.404 |
|
| 2008 |
Pabst TM, Carta G, Ramasubramanyan N, Hunter AK, Mensah P, Gustafson ME. Separation of protein charge variants with induced pH gradients using anion exchange chromatographic columns. Biotechnology Progress. 24: 1096-106. PMID 19194919 DOI: 10.1002/Btpr.53 |
0.802 |
|
| 2008 |
Hunter AK, Suda EJ, Herberg JT, Thomas KE, Shell RE, Gustafson ME, Ho SV. Separation of recombinant apolipoprotein A-I(Milano) modified forms and aggregates in an industrial ion-exchange chromatography unit operation. Journal of Chromatography. A. 1204: 42-7. PMID 18701112 DOI: 10.1016/J.Chroma.2008.07.059 |
0.479 |
|
| 2008 |
Hunter AK, Hoeltzli SD, Johnson GV, Gustafson ME, Ho SV. Use of cyclohexanedimethanol as a nonflammable organic solvent for industrial scale reversed phase chromatography. Journal of Chromatography. A. 1202: 107-10. PMID 18620358 DOI: 10.1016/J.Chroma.2008.06.032 |
0.365 |
|
| 2008 |
Pabst TM, Antos D, Carta G, Ramasubramanyan N, Hunter AK. Protein separations with induced pH gradients using cation-exchange chromatographic columns containing weak acid groups. Journal of Chromatography. A. 1181: 83-94. PMID 18194806 DOI: 10.1016/J.Chroma.2007.12.054 |
0.801 |
|
| 2008 |
Pabst TM, Carta G, Hunter AK, Ramasubramanyan N. Preparative separations of acidic protein mixtures and protein charge variants by chromatofocusing with unretained buffers Aiche Annual Meeting, Conference Proceedings. |
0.736 |
|
| 2007 |
Pabst TM, Buckley JJ, Ramasubramanyan N, Hunter AK. Comparison of strong anion-exchangers for the purification of a PEGylated protein. Journal of Chromatography. A. 1147: 172-82. PMID 17346720 DOI: 10.1016/J.Chroma.2007.02.051 |
0.793 |
|
| 2007 |
Hunter AK, Suda EJ, Das TK, Shell RE, Herberg JT, Ramasubramanyan N, Gustafson ME, Ho SV. Impact of denaturation with urea on recombinant apolipoprotein A-IMilano ion-exchange adsorption: equilibrium uptake behavior and protein mass transfer kinetics. Biotechnology Journal. 2: 110-20. PMID 17136731 DOI: 10.1002/Biot.200600165 |
0.428 |
|
| 2007 |
Pabst TM, Buckley JJ, Ramasubramanyan N, Hunter AK. Evaluation of binding and elution behavior of a PEGylated protein on anion exchange columns Aiche Annual Meeting, Conference Proceedings. |
0.789 |
|
| 2002 |
Hunter AK, Carta G. Protein adsorption on novel acrylamido-based polymeric ion-exchangers. IV. Effects of protein size on adsorption capacity and rate. Journal of Chromatography. A. 971: 105-16. PMID 12350106 DOI: 10.1016/S0021-9673(02)01027-0 |
0.65 |
|
| 2001 |
Hunter AK, Carta G. Effects of bovine serum albumin heterogeneity on frontal analysis with anion-exchange media. Journal of Chromatography. A. 937: 13-9. PMID 11765079 DOI: 10.1016/S0021-9673(01)01301-2 |
0.622 |
|
| 2001 |
Hunter AK, Carta G. Protein adsorption on novel acrylamido-based polymeric ion-exchangers. III. Salt concentration effects and elution behavior. Journal of Chromatography. A. 930: 79-93. PMID 11681582 DOI: 10.1016/S0021-9673(01)01162-1 |
0.637 |
|
| 2000 |
Hunter AK, Carta G. Protein adsorption on novel acrylamido-based polymeric ion exchangers. II. Adsorption rates and column behavior. Journal of Chromatography. A. 897: 81-97. PMID 11128228 DOI: 10.1016/S0021-9673(00)00865-7 |
0.647 |
|
| 2000 |
Hunter AK, Carta G. Protein adsorption on novel acrylamido-based polymeric ion-exchangers. I. Morphology and equilibrium adsorption. Journal of Chromatography. A. 897: 65-80. PMID 11128227 DOI: 10.1016/S0021-9673(00)00864-5 |
0.636 |
|
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