Mitchell B. Schaffler - Publications

Affiliations: 
Engineering City University of New York, New York, NY, United States 
Area:
Biomedical Engineering

128 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Poudel SB, Frikha-Benayed D, Ruff RR, Yildirim G, Dixit M, Korstanje R, Robinson L, Miller RA, Harrison DE, Strong JR, Schaffler MB, Yakar S. Targeting mitochondrial dysfunction using methylene blue or mitoquinone to improve skeletal aging. Aging. 15. PMID 38535998 DOI: 10.18632/aging.205147  0.34
2023 Lewis KJ, Boorman-Padgett JF, Castaneda M, Spray DC, Thi MM, Schaffler MB. A Fluorescent Intravital Imaging Approach to Study Load-Induced Calcium Signaling Dynamics in Mouse Osteocytes. Journal of Visualized Experiments : Jove. PMID 36912542 DOI: 10.3791/64366  0.378
2022 Dixit M, Louis LD, Basta-Pljakic J, Yildirim G, Poudel SB, Kumararaja F, List EO, Duran SO, Kopchick JJ, Ruff RR, Schaffler MB, Yakar S. Lifelong excess in GH elicits sexual dimorphic effects on skeletal morphology and bone mechanical properties. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 36069368 DOI: 10.1002/jbmr.4699  0.496
2021 Dixit M, Duran-Ortiz S, Yildirim G, Poudel SB, Louis LD, Bartke A, Schaffler MB, Kopchick JJ, Yakar S. Induction of somatopause in adult mice compromises bone morphology and exacerbates bone loss during aging. Aging Cell. e13505. PMID 34811875 DOI: 10.1111/acel.13505  0.498
2021 Coffman AA, Basta-Pljakic J, Guerra RM, Ebetino FH, Lundy MW, Majeska RJ, Schaffler MB. Reply to: A Bisphosphonate With a Low Hydroxyapatite Binding Affinity Prevents Bone Loss in Mice After Ovariectomy and Reverses Rapidly With Treatment Cessation. Jbmr Plus. 5: e10492. PMID 34258501 DOI: 10.1002/jbm4.10492  0.338
2021 Dixit M, Liu Z, Poudel SB, Yildirim G, Zhang YZ, Mehta S, Murik O, Altarescu G, Kobayashi Y, Shimizu E, Schaffler MB, Yakar S. Skeletal Response to Insulin in the Naturally Occurring Type 1 Diabetes Mellitus Mouse Model. Jbmr Plus. 5: e10483. PMID 33977201 DOI: 10.1002/jbm4.10483  0.443
2021 Coffman AA, Basta-Pljakic J, Guerra RM, Ebetino FH, Lundy MW, Majeska RJ, Schaffler MB. A Bisphosphonate With a Low Hydroxyapatite Binding Affinity Prevents Bone Loss in Mice After Ovariectomy and Reverses Rapidly With Treatment Cessation. Jbmr Plus. 5: e10476. PMID 33869992 DOI: 10.1002/jbm4.10476  0.467
2020 McCutcheon S, Majeska RJ, Spray DC, Schaffler MB, Vazquez M. Apoptotic osteocytes induce RANKL production in bystanders via purinergic signaling and activation of pannexin channels. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 31910292 DOI: 10.1002/Jbmr.3954  0.489
2019 Green MD, Schaffler M, Barabino GA. L-Glutamine Increases IGF-1 Liver Expression to Prevent Bone Loss in Sickle Mice Blood. 134: 3561-3561. DOI: 10.1182/Blood-2019-128950  0.448
2018 Liu Z, Solesio ME, Schaffler MB, Frikha-Benayed D, Rosen CJ, Werner H, Kopchick JJ, Pavlov EV, Abramov AY, Yakar S. Mitochondrial Function Is Compromised in Cortical Bone Osteocytes of Long-Lived Growth Hormone Receptor Null Mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 30216544 DOI: 10.1002/Jbmr.3573  0.367
2018 Bell R, Robles-Harris MA, Anderson M, Laudier D, Schaffler MB, Flatow EL, Andarawis-Puri N. Inhibition of apoptosis exacerbates fatigue-damage tendon injuries in an in vivo rat model. European Cells & Materials. 36: 44-56. PMID 30058060 DOI: 10.22203/Ecm.V036A04  0.311
2018 Seref-Ferlengez Z, Urban-Maldonado M, Sun HB, Schaffler MB, Suadicani SO, Thi MM. Role of pannexin 1 channels in load-induced skeletal response. Annals of the New York Academy of Sciences. PMID 29952014 DOI: 10.1111/Nyas.13914  0.387
2017 Cabahug-Zuckerman P, Stout RF, Majeska RJ, Thi MM, Spray DC, Weinbaum S, Schaffler MB. Potential Role for a Specialized β3 Integrin-Based Structure On Osteocyte Processes in Bone Mechanosensation. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 29087614 DOI: 10.1002/Jor.23792  0.375
2017 Lewis KJ, Frikha-Benayed D, Louie J, Stephen S, Spray DC, Thi MM, Seref-Ferlengez Z, Majeska RJ, Weinbaum S, Schaffler MB. Osteocyte calcium signals encode strain magnitude and loading frequency in vivo. Proceedings of the National Academy of Sciences of the United States of America. PMID 29078317 DOI: 10.1073/Pnas.1707863114  0.454
2017 Liu Z, Han T, Werner H, Rosen CJ, Schaffler MB, Yakar S. Reduced serum IGF-1 associated with hepatic osteodystrophy is a main determinant of low cortical but not trabecular bone mass. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 28902430 DOI: 10.1002/Jbmr.3290  0.494
2017 Liu Z, Han T, Fishman S, Butler J, Zimmermann T, Tremblay F, Harbison C, Agrawal N, Kopchick JJ, Schaffler MB, Yakar S. Ablation of hepatic production of the acid labile subunit in the bovine-GH transgenic mice; effects on organ and skeletal growth. Endocrinology. PMID 28475811 DOI: 10.1210/En.2016-1952  0.394
2016 Kennedy OD, Lendhey M, Mauer P, Philip A, Basta-Pljakic J, Schaffler MB. Microdamage induced by in vivo Reference Point Indentation in mice is repaired by osteocyte-apoptosis mediated remodeling. Bone. PMID 27919734 DOI: 10.1016/J.Bone.2016.11.029  0.538
2016 Kaya S, Basta-Pljakic J, Seref-Ferlengez Z, Majeska RJ, Cardoso L, Bromage T, Zhang Q, Flach CR, Mendelsohn R, Yakar S, Fritton SP, Schaffler MB. Lactation Induced Changes in the Volume of Osteocyte Lacunar-Canalicular Space Alter Mechanical Properties in Cortical Bone Tissue. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 27859586 DOI: 10.1002/Jbmr.3044  0.564
2016 Dolan EB, Tallon D, Cheung WY, Schaffler MB, Kennedy OD, McNamara LM. Thermally induced osteocyte damage initiates pro-osteoclastogenic gene expression in vivo. Journal of the Royal Society, Interface / the Royal Society. 13. PMID 27335224 DOI: 10.1098/Rsif.2016.0337  0.464
2016 Frikha-Benayed D, Basta-Pljakic J, Majeska RJ, Schaffler MB. Regional Differences in Oxidative Metabolism and Mitochondrial Activity among Cortical Bone Osteocytes. Bone. PMID 27260646 DOI: 10.1016/J.Bone.2016.05.011  0.436
2016 Seref-Ferlengez Z, Maung S, Schaffler MB, Spray DC, Suadicani SO, Thi MM. P2X7R-Panx1 Complex Impairs Bone Mechanosignaling under High Glucose Levels Associated with Type-1 Diabetes. Plos One. 11: e0155107. PMID 27159053 DOI: 10.1371/Journal.Pone.0155107  0.469
2016 Cabahug-Zuckerman P, Frikha-Benayed D, Majeska RJ, Tuthill A, Yakar S, Judex S, Schaffler MB. Osteocyte Apoptosis Caused by Hindlimb Unloading is Required to Trigger Osteocyte RANKL Production and Subsequent Resorption of Cortical and Trabecular Bone in Mice Femurs. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 26852281 DOI: 10.1002/Jbmr.2807  0.563
2015 Cheung WY, Fritton JC, Morgan S, Seref-Ferlengez Z, Basta-Pljakic J, Thi MM, Suadicani SO, Spray DC, Majeska RJ, Schaffler MB. Pannexin-1 and P2X7-Receptor Are Required for Apoptotic Osteocytes in Fatigued Bone to Trigger RANKL Production in Neighboring Bystander Osteocytes. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 26553756 DOI: 10.1002/Jbmr.2740  0.494
2015 Liu Z, Kennedy OD, Cardoso L, Basta-Pljakic J, Partridge NC, Schaffler MB, Rosen CJ, Yakar S. DMP-1-mediated Ghr gene recombination compromises skeletal development and impairs skeletal response to intermittent PTH. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26481310 DOI: 10.1096/Fj.15-275859  0.576
2015 Smaldone S, Clayton NP, Del Solar M, Pascual-Gonzales G, Cheng SH, Wentworth BM, Schaffler MB, Ramirez F. Fibrillin-1 Regulates Skeletal Stem Cell Differentiation by Modulating TGFβ Activity Within the Marrow Niche. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 26189658 DOI: 10.1002/jbmr.2598  0.461
2015 Seref-Ferlengez Z, Kennedy OD, Schaffler MB. Bone microdamage, remodeling and bone fragility: how much damage is too much damage? Bonekey Reports. 4: 644. PMID 25848533 DOI: 10.1038/Bonekey.2015.11  0.533
2015 Cardoso L, Schaffler MB. Changes of elastic constants and anisotropy patterns in trabecular bone during disuse-induced bone loss assessed by poroelastic ultrasound. Journal of Biomechanical Engineering. 137. PMID 25412022 DOI: 10.1115/1.4029179  0.542
2015 Coughlin TR, Voisin M, Schaffler MB, Niebur GL, McNamara LM. Primary cilia exist in a small fraction of cells in trabecular bone and marrow. Calcified Tissue International. 96: 65-72. PMID 25398598 DOI: 10.1007/S00223-014-9928-6  0.52
2014 Seref-Ferlengez Z, Basta-Pljakic J, Kennedy OD, Philemon CJ, Schaffler MB. Structural and mechanical repair of diffuse damage in cortical bone in vivo. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 29: 2537-44. PMID 25042459 DOI: 10.1002/Jbmr.2309  0.506
2014 Kennedy OD, Laudier DM, Majeska RJ, Sun HB, Schaffler MB. Osteocyte apoptosis is required for production of osteoclastogenic signals following bone fatigue in vivo. Bone. 64: 132-7. PMID 24709687 DOI: 10.1016/j.bone.2014.03.049  0.37
2014 Kennedy OD, Sun H, Wu Y, Courtland HW, Williams GA, Cardoso L, Basta-Pljakic J, Schaffler MB, Yakar S. Skeletal response of male mice to anabolic hormone therapy in the absence of the Igfals gene. Endocrinology. 155: 987-99. PMID 24424061 DOI: 10.1210/En.2013-1819  0.403
2014 Schaffler MB, Cheung WY, Majeska R, Kennedy O. Osteocytes: master orchestrators of bone. Calcified Tissue International. 94: 5-24. PMID 24042263 DOI: 10.1007/S00223-013-9790-Y  0.52
2013 Thi MM, Suadicani SO, Schaffler MB, Weinbaum S, Spray DC. Mechanosensory responses of osteocytes to physiological forces occur along processes and not cell body and require αVβ3 integrin. Proceedings of the National Academy of Sciences of the United States of America. 110: 21012-7. PMID 24324138 DOI: 10.1073/Pnas.1321210110  0.348
2013 Wu D, Schaffler MB, Weinbaum S, Spray DC. Matrix-dependent adhesion mediates network responses to physiological stimulation of the osteocyte cell process. Proceedings of the National Academy of Sciences of the United States of America. 110: 12096-101. PMID 23818616 DOI: 10.1073/Pnas.1310003110  0.403
2013 Wu Y, Sun H, Basta-Pljakic J, Cardoso L, Kennedy OD, Jasper H, Domené H, Karabatas L, Guida C, Schaffler MB, Rosen CJ, Yakar S. Serum IGF-1 is insufficient to restore skeletal size in the total absence of the growth hormone receptor Journal of Bone and Mineral Research. 28: 1575-1586. PMID 23456957 DOI: 10.1002/Jbmr.1920  0.333
2013 Courtland HW, Kennedy OD, Wu Y, Gao Y, Sun H, Schaffler MB, Yakar S. Low levels of plasma IGF-1 inhibit intracortical bone remodeling during aging. Age (Dordrecht, Netherlands). 35: 1691-703. PMID 22976122 DOI: 10.1007/s11357-012-9469-8  0.435
2012 Kennedy OD, Schaffler MB. The roles of osteocyte signaling in bone. The Journal of the American Academy of Orthopaedic Surgeons. 20: 670-1. PMID 23027697 DOI: 10.5435/Jaaos-20-10-670  0.518
2012 Schaffler MB, Kennedy OD. Osteocyte signaling in bone. Current Osteoporosis Reports. 10: 118-25. PMID 22552701 DOI: 10.1007/S11914-012-0105-4  0.58
2012 Kennedy OD, Herman BC, Laudier DM, Majeska RJ, Sun HB, Schaffler MB. Activation of resorption in fatigue-loaded bone involves both apoptosis and active pro-osteoclastogenic signaling by distinct osteocyte populations. Bone. 50: 1115-22. PMID 22342796 DOI: 10.1016/J.Bone.2012.01.025  0.467
2011 Lynch ME, Main RP, Xu Q, Schmicker TL, Schaffler MB, Wright TM, van der Meulen MC. Tibial compression is anabolic in the adult mouse skeleton despite reduced responsiveness with aging. Bone. 49: 439-46. PMID 21642027 DOI: 10.1016/J.Bone.2011.05.017  0.498
2011 Arteaga-Solis E, Sui-Arteaga L, Kim M, Schaffler MB, Jepsen KJ, Pleshko N, Ramirez F. Material and mechanical properties of bones deficient for fibrillin-1 or fibrillin-2 microfibrils. Matrix Biology : Journal of the International Society For Matrix Biology. 30: 188-94. PMID 21440062 DOI: 10.1016/J.Matbio.2011.03.004  0.567
2011 Lee JY, Zhou Z, Taub PJ, Ramcharan M, Li Y, Akinbiyi T, Maharam ER, Leong DJ, Laudier DM, Ruike T, Torina PJ, Zaidi M, Majeska RJ, Schaffler MB, Flatow EL, et al. BMP-12 treatment of adult mesenchymal stem cells in vitro augments tendon-like tissue formation and defect repair in vivo. Plos One. 6: e17531. PMID 21412429 DOI: 10.1371/Journal.Pone.0017531  0.403
2010 Herman BC, Cardoso L, Majeska RJ, Jepsen KJ, Schaffler MB. Activation of bone remodeling after fatigue: Differential response to linear microcracks and diffuse damage Bone. 47: 766-772. PMID 20633708 DOI: 10.1016/J.Bone.2010.07.006  0.459
2010 Lynch ME, Main RP, Xu Q, Walsh DJ, Schaffler MB, Wright TM, van der Meulen MC. Cancellous bone adaptation to tibial compression is not sex dependent in growing mice. Journal of Applied Physiology (Bethesda, Md. : 1985). 109: 685-91. PMID 20576844 DOI: 10.1152/Japplphysiol.00210.2010  0.502
2010 Fung DT, Wang VM, Andarawis-Puri N, Basta-Pljakic J, Li Y, Laudier DM, Sun HB, Jepsen KJ, Schaffler MB, Flatow EL. Early response to tendon fatigue damage accumulation in a novel in vivo model. Journal of Biomechanics. 43: 274-9. PMID 19939387 DOI: 10.1016/J.Jbiomech.2009.08.039  0.309
2010 Emerton KB, Hu B, Woo AA, Sinofsky A, Hernandez C, Majeska RJ, Jepsen KJ, Schaffler MB. Osteocyte apoptosis and control of bone resorption following ovariectomy in mice. Bone. 46: 577-83. PMID 19925896 DOI: 10.1016/J.Bone.2009.11.006  0.768
2010 Fritton JC, Emerton KB, Sun H, Kawashima Y, Mejia W, Wu Y, Rosen CJ, Panus D, Bouxsein M, Majeska RJ, Schaffler MB, Yakar S. Growth hormone protects against ovariectomy-induced bone loss in states of low circulating insulin-like growth factor (IGF-1). Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 235-46. PMID 19619004 DOI: 10.1359/Jbmr.090723  0.785
2009 Li W, You L, Schaffler MB, Wang L. The dependency of solute diffusion on molecular weight and shape in intact bone. Bone. 45: 1017-23. PMID 19647808 DOI: 10.1016/J.Bone.2009.07.076  0.327
2009 McNamara LM, Majeska RJ, Weinbaum S, Friedrich V, Schaffler MB. Attachment of osteocyte cell processes to the bone matrix. Anatomical Record (Hoboken, N.J. : 2007). 292: 355-63. PMID 19248169 DOI: 10.1002/Ar.20869  0.442
2009 Boskey AL, Gelb BD, Pourmand E, Kudrashov V, Doty SB, Spevak L, Schaffler MB. Ablation of cathepsin k activity in the young mouse causes hypermineralization of long bone and growth plates. Calcified Tissue International. 84: 229-39. PMID 19172215 DOI: 10.1007/S00223-008-9214-6  0.476
2009 Kawashima Y, Fritton JC, Yakar S, Epstein S, Schaffler MB, Jepsen KJ, LeRoith D. Type 2 diabetic mice demonstrate slender long bones with increased fragility secondary to increased osteoclastogenesis. Bone. 44: 648-55. PMID 19150422 DOI: 10.1016/J.Bone.2008.12.012  0.536
2009 Cardoso L, Herman BC, Verborgt O, Laudier D, Majeska RJ, Schaffler MB. Osteocyte apoptosis controls activation of intracortical resorption in response to bone fatigue. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 24: 597-605. PMID 19049324 DOI: 10.1359/Jbmr.081210  0.53
2009 Yakar S, Rosen CJ, Bouxsein ML, Sun H, Mejia W, Kawashima Y, Wu Y, Emerton K, Williams V, Jepsen K, Schaffler MB, Majeska RJ, Gavrilova O, Gutierrez M, Hwang D, et al. Serum complexes of insulin-like growth factor-1 modulate skeletal integrity and carbohydrate metabolism. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 709-19. PMID 18952711 DOI: 10.1096/Fj.08-118976  0.731
2008 Wang Y, McNamara LM, Schaffler MB, Weinbaum S. Strain amplification and integrin based signaling in osteocytes. Journal of Musculoskeletal & Neuronal Interactions. 8: 332-4. PMID 19147963  0.4
2008 Wiren KM, Semirale AA, Zhang XW, Woo A, Tommasini SM, Price C, Schaffler MB, Jepsen KJ. Targeting of androgen receptor in bone reveals a lack of androgen anabolic action and inhibition of osteogenesis: a model for compartment-specific androgen action in the skeleton. Bone. 43: 440-51. PMID 18595795 DOI: 10.1016/J.Bone.2008.04.026  0.577
2008 Choi BG, Vilahur G, Zafar MU, Cardoso L, Yadegar D, Ibanez B, Tunstead J, Viles-Gonzalez JF, Schaffler MB, Fuster V, Badimon JJ. Selective estrogen receptor modulation influences atherosclerotic plaque composition in a rabbit menopause model. Atherosclerosis. 201: 76-84. PMID 18367192 DOI: 10.1016/J.Atherosclerosis.2008.01.017  0.311
2008 Choi BG, Vilahur G, Cardoso L, Fritton JC, Ibanez B, Zafar MU, Yadegar D, Speidl WS, Schaffler MB, Fuster V, Badimon JJ. Ovariectomy increases vascular calcification via the OPG/RANKL cytokine signalling pathway European Journal of Clinical Investigation. 38: 211-217. PMID 18279396 DOI: 10.1111/J.1365-2362.2008.01930.X  0.32
2008 Fritton JC, Schaffler MB. Bone Quality Osteoporosis, Two-Volume Set. 625-641. DOI: 10.1016/B978-012370544-0.50026-4  0.401
2007 Wang Y, McNamara LM, Schaffler MB, Weinbaum S. A model for the role of integrins in flow induced mechanotransduction in osteocytes. Proceedings of the National Academy of Sciences of the United States of America. 104: 15941-6. PMID 17895377 DOI: 10.1016/S0021-9290(06)83892-3  0.461
2007 Mosig RA, Dowling O, DiFeo A, Ramirez MC, Parker IC, Abe E, Diouri J, Aqeel AA, Wylie JD, Oblander SA, Madri J, Bianco P, Apte SS, Zaidi M, Doty SB, ... ... Schaffler MB, et al. Loss of MMP-2 disrupts skeletal and craniofacial development and results in decreased bone mineralization, joint erosion and defects in osteoblast and osteoclast growth. Human Molecular Genetics. 16: 1113-23. PMID 17400654 DOI: 10.1093/Hmg/Ddm060  0.524
2007 Xiang Y, Yingling VR, Malique R, Li CY, Schaffler MB, Raphan T. Comparative assessment of bone mass and structure using texture-based and histomorphometric analyses. Bone. 40: 544-52. PMID 17049942 DOI: 10.1016/J.Bone.2006.08.015  0.504
2007 Yingling VR, Xiang Y, Raphan T, Schaffler MB, Koser K, Malique R. The effect of a short-term delay of puberty on trabecular bone mass and structure in female rats: a texture-based and histomorphometric analysis. Bone. 40: 419-24. PMID 16979963 DOI: 10.1016/J.Bone.2006.07.019  0.477
2006 Li CY, Jepsen KJ, Majeska RJ, Zhang J, Ni R, Gelb BD, Schaffler MB. Mice lacking cathepsin K maintain bone remodeling but develop bone fragility despite high bone mass. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 21: 865-75. PMID 16753017 DOI: 10.1359/Jbmr.060313  0.566
2006 McNamara LM, Ederveen AG, Lyons CG, Price C, Schaffler MB, Weinans H, Prendergast PJ. Strength of cancellous bone trabecular tissue from normal, ovariectomized and drug-treated rats over the course of ageing. Bone. 39: 392-400. PMID 16644297 DOI: 10.1016/J.Bone.2006.02.070  0.559
2006 Sun L, Peng Y, Sharrow AC, Iqbal J, Zhang Z, Papachristou DJ, Zaidi S, Zhu LL, Yaroslavskiy BB, Zhou H, Zallone A, Sairam MR, Kumar TR, Bo W, Braun J, ... ... Schaffler MB, et al. FSH directly regulates bone mass. Cell. 125: 247-60. PMID 16630814 DOI: 10.1016/J.Cell.2006.01.051  0.547
2005 Li CY, Schaffler MB, Wolde-Semait HT, Hernandez CJ, Jepsen KJ. Genetic background influences cortical bone response to ovariectomy. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 2150-8. PMID 16294268 DOI: 10.1359/Jbmr.050819  0.521
2005 Wang L, Wang Y, Han Y, Henderson SC, Majeska RJ, Weinbaum S, Schaffler MB. In situ measurement of solute transport in the bone lacunar-canalicular system. Proceedings of the National Academy of Sciences of the United States of America. 102: 11911-6. PMID 16087872 DOI: 10.1073/Pnas.0505193102  0.569
2005 Tommasini SM, Nasser P, Schaffler MB, Jepsen KJ. Relationship between bone morphology and bone quality in male tibias: implications for stress fracture risk. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 1372-80. PMID 16007335 DOI: 10.1359/Jbmr.050326  0.509
2005 Yang Li C, Majeska RJ, Laudier DM, Mann R, Schaffler MB. High-dose risedronate treatment partially preserves cancellous bone mass and microarchitecture during long-term disuse. Bone. 37: 287-95. PMID 16006205 DOI: 10.1016/J.Bone.2005.04.041  0.552
2005 Li CY, Price C, Delisser K, Nasser P, Laudier D, Clement M, Jepsen KJ, Schaffler MB. Long-term disuse osteoporosis seems less sensitive to bisphosphonate treatment than other osteoporosis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 117-24. PMID 15619677 DOI: 10.1359/Jbmr.041010  0.557
2004 Hernandez CJ, Majeska RJ, Schaffler MB. Osteocyte density in woven bone. Bone. 35: 1095-9. PMID 15542034 DOI: 10.1016/J.Bone.2004.07.002  0.583
2004 Han Y, Cowin SC, Schaffler MB, Weinbaum S. Mechanotransduction and strain amplification in osteocyte cell processes. Proceedings of the National Academy of Sciences of the United States of America. 101: 16689-94. PMID 15539460 DOI: 10.1073/Pnas.0407429101  0.312
2004 You LD, Weinbaum S, Cowin SC, Schaffler MB. Ultrastructure of the osteocyte process and its pericellular matrix. The Anatomical Record. Part a, Discoveries in Molecular, Cellular, and Evolutionary Biology. 278: 505-13. PMID 15164337 DOI: 10.1002/Ar.A.20050  0.431
2004 Akkus O, Adar F, Schaffler MB. Age-related changes in physicochemical properties of mineral crystals are related to impaired mechanical function of cortical bone. Bone. 34: 443-53. PMID 15003792 DOI: 10.1016/J.Bone.2003.11.003  0.433
2004 McCreadie BR, Hollister SJ, Schaffler MB, Goldstein SA. Osteocyte lacuna size and shape in women with and without osteoporotic fracture. Journal of Biomechanics. 37: 563-72. PMID 14996569 DOI: 10.1016/S0021-9290(03)00287-2  0.425
2003 Tami AE, Nasser P, Schaffler MB, Knothe Tate ML. Noninvasive fatigue fracture model of the rat ulna Journal of Orthopaedic Research. 21: 1018-1024. PMID 14554214 DOI: 10.1016/S0736-0266(03)00099-8  0.429
2003 Schaffler MB. Role of bone turnover in microdamage. Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation For Osteoporosis and the National Osteoporosis Foundation of the Usa. 14: S73-7; discussion S7. PMID 14504710 DOI: 10.1007/S00198-003-1477-1  0.578
2003 Akkus O, Polyakova-Akkus A, Adar F, Schaffler MB. Aging of microstructural compartments in human compact bone. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 18: 1012-9. PMID 12817753 DOI: 10.1359/Jbmr.2003.18.6.1012  0.5
2002 Tami AE, Nasser P, Verborgt O, Schaffler MB, Knothe Tate ML. The role of interstitial fluid flow in the remodeling response to fatigue loading Journal of Bone and Mineral Research. 17: 2030-2037. PMID 12412811 DOI: 10.1359/Jbmr.2002.17.11.2030  0.414
2002 Vashishth D, Gibson G, Kimura J, Schaffler MB, Fyhrie DP. Determination of bone volume by osteocyte population. The Anatomical Record. 267: 292-5. PMID 12124907 DOI: 10.1002/Ar.10114  0.478
2002 Verborgt O, Tatton NA, Majeska RJ, Schaffler MB. Spatial distribution of Bax and Bcl-2 in osteocytes after bone fatigue: complementary roles in bone remodeling regulation? Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 17: 907-14. PMID 12009022 DOI: 10.1359/Jbmr.2002.17.5.907  0.516
2002 Yeni YN, Schaffler MB, Gibson G, Fyhrie DP. Prestress due to dimensional changes caused by demineralization: a potential mechanism for microcracking in bone. Annals of Biomedical Engineering. 30: 217-25. PMID 11962773 DOI: 10.1114/1.1451078  0.576
2002 Akkus O, Adar F, Schaffler MB. Strain and fracture induced changes in bone mineral crystals Asme International Mechanical Engineering Congress and Exposition, Proceedings. 309-310. DOI: 10.1115/IMECE2002-32600  0.336
2002 Akkus O, Adar F, Schaffler MB. Increased collagen mineralization affects the yield stress but not the yield strain in cortical bone of rats: Implications for age-related tissue embrittlement Asme International Mechanical Engineering Congress and Exposition, Proceedings. 307-308. DOI: 10.1115/IMECE2002-32599  0.337
2001 You L, Cowin SC, Schaffler MB, Weinbaum S. A model for strain amplification in the actin cytoskeleton of osteocytes due to fluid drag on pericellular matrix. Journal of Biomechanics. 34: 1375-86. PMID 11672712 DOI: 10.1016/S0021-9290(01)00107-5  0.424
2001 Vashishth D, Gibson GJ, Khoury JI, Schaffler MB, Kimura J, Fyhrie DP. Influence of nonenzymatic glycation on biomechanical properties of cortical bone Bone. 28: 195-201. PMID 11182378 DOI: 10.1016/S8756-3282(00)00434-8  0.555
2000 Vashishth D, Verborgt O, Divine G, Schaffler MB, Fyhrie DP. Decline in osteocyte lacunar density in human cortical bone is associated with accumulation of microcracks with age Bone. 26: 375-380. PMID 10719281 DOI: 10.1016/S8756-3282(00)00236-2  0.509
2000 Vashishth D, Koontz J, Qiu SJ, Lundin-Cannon D, Yeni YN, Schaffler MB, Fyhrie DP. In vivo diffuse damage in human vertebral trabecular bone Bone. 26: 147-152. PMID 10678409 DOI: 10.1016/S8756-3282(99)00253-7  0.443
2000 Verborgt O, Gibson GJ, Schaffler MB. Loss of osteocyte integrity in association with microdamage and bone remodeling after fatigue in vivo. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 15: 60-7. PMID 10646115 DOI: 10.1359/Jbmr.2000.15.1.60  0.588
2000 Ciarelli TE, Fyhrie DP, Schaffler MB, Goldstein SA. Variations in three-dimensional cancellous bone architecture of the proximal femur in female hip fractures and in controls Journal of Bone and Mineral Research. 15: 32-40. PMID 10646112 DOI: 10.1359/Jbmr.2000.15.1.32  0.46
2000 Schaffler MB, Jepsen KJ. Fatigue and repair in bone International Journal of Fatigue. 22: 839-846. DOI: 10.1016/S0142-1123(00)00053-0  0.532
1999 Richards M, Goulet JA, Schaffler MB, Goldstein SA. Temporal and spatial characterization of regenerate bone in the lengthened rabbit tibia. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 14: 1978-86. PMID 10571699 DOI: 10.1359/Jbmr.1999.14.11.1978  0.568
1999 Richards M, Waanders NA, Weiss JA, Bhatia V, Senunas LE, Schaffler MB, Goldstein SA, Goulet JA. Reduced gap strains induce changes in bone regeneration during distraction. Journal of Biomechanical Engineering. 121: 348-55. PMID 10396702 DOI: 10.1115/1.2798331  0.518
1998 Bentolila V, Boyce TM, Fyhrie DP, Drumb R, Skerry TM, Schaffler MB. Intracortical remodeling in adult rat long bones after fatigue loading Bone. 23: 275-281. PMID 9737350 DOI: 10.1016/S8756-3282(98)00104-5  0.544
1998 Boyce TM, Fyhrie DP, Glotkowski MC, Radin EL, Schaffler MB. Damage type and strain mode associations in human compact bone bending fatigue Journal of Orthopaedic Research. 16: 322-329. PMID 9671927 DOI: 10.1002/Jor.1100160308  0.414
1998 Moed BR, Kim EC, van Holsbeeck M, Schaffler MB, Subramanian S, Bouffard JA, Craig JG. Ultrasound for the early diagnosis of tibial fracture healing after static interlocked nailing without reaming: histologic correlation using a canine model. Journal of Orthopaedic Trauma. 12: 200-5. PMID 9553862 DOI: 10.1097/00005131-199803000-00012  0.36
1997 Jepsen KJ, Schaffler MB, Kuhn JL, Goulet RW, Bonadio J, Goldstein SA. Type I collagen mutation alters the strength and fatigue behavior of Mov13 cortical tissue Journal of Biomechanics. 30: 1141-1147. PMID 9456382 DOI: 10.1016/S0021-9290(97)00088-2  0.444
1997 Burr DB, Forwood MR, Fyhrie DP, Martin RB, Schaffler MB, Turner CH. Bone microdamage and skeletal fragility in osteoporotic and stress fractures Journal of Bone and Mineral Research. 12: 6-15. PMID 9240720 DOI: 10.1359/Jbmr.1997.12.1.6  0.47
1997 Burr DB, Schaffler MB. The involvement of subchondral mineralized tissues in osteoarthrosis: quantitative microscopic evidence. Microscopy Research and Technique. 37: 343-57. PMID 9185156 DOI: 10.1002/(Sici)1097-0029(19970515)37:4<343::Aid-Jemt9>3.0.Co;2-L  0.513
1996 Wenzel TE, Schaffler MB, Fyhrie DP. In vivo trabecular microcracks in human vertebral bone Bone. 19: 89-95. PMID 8853850 DOI: 10.1016/8756-3282(96)88871-5  0.408
1996 Jepsen KJ, Goldstein SA, Kuhn JL, Schaffler MB, Bonadio J. Type-I collagen mutation compromises the post-yield behavior of Mov13 long bone Journal of Orthopaedic Research. 14: 493-499. PMID 8676263 DOI: 10.1002/Jor.1100140320  0.54
1995 Schaffler MB, Choi K, Milgrom C. Aging and matrix microdamage accumulation in human compact bone. Bone. 17: 521-25. PMID 8835305 DOI: 10.1016/8756-3282(95)00370-3  0.552
1995 Fyhrie DP, Lang SM, Hoshaw SJ, Schaffler MB, Kuo RF. Human vertebral cancellous bone surface distribution Bone. 17: 287-291. PMID 8541143 DOI: 10.1016/8756-3282(95)00218-3  0.442
1995 Fyhrie DP, Schaffler MB. The adaptation of bone apparent density to applied load Journal of Biomechanics. 28: 135-143,145-146. PMID 7896856 DOI: 10.1016/0021-9290(94)00059-D  0.413
1995 Gibson GJ, Lin DL, Schaffler MB, Kimura JH. Endochondral resorption of chick sterna in culture. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 13: 542-52. PMID 7674070 DOI: 10.1002/Jor.1100130409  0.369
1995 Gibson GJ, Kohler WJ, Schaffler MB. Chondrocyte apoptosis in endochondral ossification of chick sterna. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 203: 468-76. PMID 7496038 DOI: 10.1002/Aja.1002030409  0.307
1994 Fyhrie DP, Schaffler MB. Failure mechanisms in human vertebral cancellous bone Bone. 15: 105-109. PMID 8024844 DOI: 10.1016/8756-3282(94)90900-8  0.456
1994 Schaffler MB, Pitchford WC, Choi K, Riddle JM. Examination of compact bone microdamage using back-scattered electron microscopy. Bone. 15: 483-8. PMID 7526878 DOI: 10.1016/8756-3282(94)90271-2  0.403
1993 Fyhrie D, Schaffler M. How human vertebral bone breaks Journal of Biomechanics. 26: 347. DOI: 10.1016/0021-9290(93)90554-R  0.443
1993 Fazzalari N, Fyhrie D, Wenzel T, Schaffler M. The development of microstructure in cancellous bone Journal of Biomechanics. 26: 331. DOI: 10.1016/0021-9290(93)90506-A  0.554
1993 Schaffler M. Fatigue and bone fragility Calcified Tissue International. 53: S67-S67. DOI: 10.1007/Bf01673405  0.556
1992 Schaffler M, Fazzalari N, Wenzel T, Fyhrie D. Fractal microstructure and the morphogenesis of trabecular bone Bone. 13: A29-A29. DOI: 10.1016/8756-3282(92)90571-D  0.566
1991 Schaffler MB, Radin EL, Burr DB. Long-term fatigue behavior of compact bone at low strain magnitude and rate. Bone. 11: 321-6. PMID 2252810 DOI: 10.1016/8756-3282(90)90087-F  0.478
1991 Jee WS, Li XJ, Schaffler MB. Adaptation of diaphyseal structure with aging and increased mechanical usage in the adult rat: a histomorphometrical and biomechanical study. The Anatomical Record. 230: 332-8. PMID 1867408 DOI: 10.1002/Ar.1092300306  0.563
1990 Ho CP, Kim RW, Schaffler MB, Sartoris DJ. Accuracy of dual-energy radiographic absorptiometry of the lumbar spine: cadaver study. Radiology. 176: 171-3. PMID 2353087 DOI: 10.1148/radiology.176.1.2353087  0.337
1989 Burr DB, Schaffler MB, Frederickson RG. Composition of the cement line and its possible mechanical role as a local interface in human compact bone. Journal of Biomechanics. 21: 939-45. PMID 3253280 DOI: 10.1016/0021-9290(88)90132-7  0.459
1989 Schaffler MB, Li XJ, Jee WS, Ho SW, Stern PJ. Skeletal tissue responses to thermal injury: an experimental study. Bone. 9: 397-406. PMID 3248203 DOI: 10.1016/8756-3282(88)90122-6  0.444
1989 Burr DB, Schaffler MB, Yang KH, Lukoschek M, Sivaneri N, Blaha JD, Radin EL. Skeletal change in response to altered strain environments: is woven bone a response to elevated strain? Bone. 10: 223-33. PMID 2803857 DOI: 10.1016/8756-3282(89)90057-4  0.355
1989 Burr DB, Schaffler MB, Yang KH, Wu DD, Lukoschek M, Kandzari D, Sivaneri N, Blaha JD, Radin EL. The effects of altered strain environments on bone tissue kinetics. Bone. 10: 215-21. PMID 2803856 DOI: 10.1016/8756-3282(89)90056-2  0.362
1989 Schaffler MB, Radin EL, Burr DB. Mechanical and morphological effects of strain rate on fatigue of compact bone. Bone. 10: 207-14. PMID 2803855 DOI: 10.1016/8756-3282(89)90055-0  0.405
1988 Schaffler MB, Burr DB. Stiffness of compact bone: effects of porosity and density. Journal of Biomechanics. 21: 13-6. PMID 3339022 DOI: 10.1016/0021-9290(88)90186-8  0.541
1987 Schaffler MB, Burr DB, Frederickson RG. Morphology of the osteonal cement line in human bone. The Anatomical Record. 217: 223-8. PMID 3578839 DOI: 10.1002/Ar.1092170302  0.421
1987 Farkas T, Boyd RD, Schaffler MB, Radin EL, Burr DB. Early vascular changes in rabbit subchondral bone after repetitive impulsive loading. Clinical Orthopaedics and Related Research. 259-267. DOI: 10.1097/00003086-198706000-00036  0.493
1985 Schaffler MB, Burr DB. Primate cortical bone microstructure: relationship to locomotion. American Journal of Physical Anthropology. 65: 191-7. PMID 6507608 DOI: 10.1002/Ajpa.1330650211  0.554
1985 Martin RB, Burr DB, Schaffler MB. Effects of age and sex on the amount and distribution of mineral in Eskimo tibiae. American Journal of Physical Anthropology. 67: 371-80. PMID 4061590 DOI: 10.1002/Ajpa.1330670409  0.428
1985 Burr DB, Martin RB, Schaffler MB, Radin EL. Bone remodeling in response to in vivo fatigue microdamage. Journal of Biomechanics. 18: 189-200. PMID 3997903 DOI: 10.1016/0021-9290(85)90204-0  0.475
1985 Schaffler MB, Burr DB. Bone microstructure: A study in comparative locomotion Journal of Biomechanics. 18: 239. DOI: 10.1016/0021-9290(85)90260-X  0.567
1983 Burr DB, Martin RB, Schaffler MB, Jurmain RD, Harner EJ, Radin EL. Osteoarthrosis: Sex-specific relationship to osteoporosis American Journal of Physical Anthropology. 61: 299-303. PMID 6614144 DOI: 10.1002/Ajpa.1330610304  0.429
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