Melvin Andersen - Publications

Environmental Sciences & Engineering University of North Carolina, Chapel Hill, Chapel Hill, NC 

81 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Xue P, Hou Y, Zuo Z, Wang Z, Ren S, Dong J, Fu J, Wang H, Andersen ME, Zhang Q, Xu Y, Pi J. Long isoforms of NRF1 negatively regulate adipogenesis via suppression of PPARγ expression. Redox Biology. 30: 101414. PMID 31931283 DOI: 10.1016/j.redox.2019.101414  0.32
2019 Li L, Fu J, Liu D, Sun J, Hou Y, Chen C, Shao J, Wang L, Wang X, Zhao R, Wang H, Andersen ME, Zhang Q, Xu Y, Pi J. Hepatocyte-specific Nrf2 deficiency mitigates high-fat diet-induced hepatic steatosis: Involvement of reduced PPARγ expression. Redox Biology. 30: 101412. PMID 31901728 DOI: 10.1016/j.redox.2019.101412  0.32
2019 Nault R, Bals B, Teymouri F, Black MB, Andersen ME, McMullen PD, Krishnan S, Kuravadi N, Paul N, Kumar S, Kannan K, Jayachandra KC, Alagappan L, Patel BD, Bogen KT, et al. A toxicogenomic approach for the risk assessment of the food contaminant acetamide. Toxicology and Applied Pharmacology. 114872. PMID 31881176 DOI: 10.1016/j.taap.2019.114872  0.52
2019 Beames T, Moreau M, Roberts LA, Mansouri K, Haider S, Smeltz M, Nicolas CI, Doheny D, Phillips MB, Yoon M, Becker RA, McMullen PD, Andersen ME, Clewell RA, Hartman JK. The role of fit-for-purpose assays within tiered testing approaches: A case study evaluating prioritized estrogen-active compounds in an in vitro human uterotrophic assay. Toxicology and Applied Pharmacology. 114774. PMID 31783037 DOI: 10.1016/j.taap.2019.114774  1
2019 Zhang Q, Caudle WM, Pi J, Bhattacharya S, Andersen ME, Kaminski NE, Conolly RB. Embracing Systems Toxicology at Single-Cell Resolution. Current Opinion in Toxicology. 16: 49-57. PMID 31768481 DOI: 10.1016/j.cotox.2019.04.003  0.32
2019 Andersen ME, McMullen PD, Phillips MB, Yoon M, Pendse SN, Clewell HJ, Hartman JK, Moreau M, Becker RA, Clewell RA. Developing context appropriate toxicity testing approaches using new alternative methods (NAMs). Altex. 36: 523-534. PMID 31664457 DOI: 10.14573/altex.1906261  1
2019 McMullen PD, Bhattacharya S, Woods CG, Pendse SN, McBride MT, Soldatow VY, Deisenroth C, LeCluyse EL, Clewell RA, Andersen ME. Identifying qualitative differences in PPARα signaling networks in human and rat hepatocytes and their significance for next generation chemical risk assessment methods. Toxicology in Vitro : An International Journal Published in Association With Bibra. PMID 31628012 DOI: 10.1016/j.tiv.2019.02.017  1
2019 McMullen PD, Pendse SN, Black MB, Mansouri K, Haider S, Andersen ME, Clewell RA. Addressing systematic inconsistencies between in vitro and in vivo transcriptomic mode of action signatures. Toxicology in Vitro : An International Journal Published in Association With Bibra. PMID 30807807 DOI: 10.1016/j.tiv.2019.02.014  1
2018 Haider S, Black MB, Parks BB, Foley B, Wetmore BA, Andersen ME, Clewell RA, Mansouri K, McMullen PD. A Qualitative Modeling Approach for Whole Genome Prediction Using High-Throughput Toxicogenomics Data and Pathway-Based Validation. Frontiers in Pharmacology. 9: 1072. PMID 30333746 DOI: 10.3389/fphar.2018.01072  1
2018 Wetmore BA, Clewell RA, Cholewa B, Parks B, Pendse SN, Black MB, Mansouri K, Haider S, Berg EL, Judson RS, Houck KA, Martin M, Clewell HJ, Andersen ME, Thomas RS, et al. Assessing bioactivity-exposure profiles of fruit and vegetable extracts in the BioMAP profiling system. Toxicology in Vitro : An International Journal Published in Association With Bibra. PMID 30218698 DOI: 10.1016/j.tiv.2018.09.006  1
2018 Hou Y, Liu Z, Zuo Z, Gao T, Fu J, Wang H, Xu Y, Liu D, Yamamoto M, Zhu B, Zhang Y, Andersen ME, Zhang Q, Pi J. Adipocyte-specific deficiency of Nfe2l1 disrupts plasticity of white adipose tissues and metabolic homeostasis in mice. Biochemical and Biophysical Research Communications. PMID 29935181 DOI: 10.1016/j.bbrc.2018.06.013  0.32
2018 Andersen ME, Cruzan G, Black MB, Pendse SN, Dodd DE, Bus JS, Sarang SS, Banton MI, Waites R, Layko DB, McMullen PD. Strain-related differences in mouse lung gene expression over a two-year period of inhalation exposure to styrene: Relevance to human risk assessment. Regulatory Toxicology and Pharmacology : Rtp. PMID 29777725 DOI: 10.1016/j.yrtph.2018.05.011  0.52
2018 McMullen PD, Andersen ME, Cholewa B, Clewell HJ, Dunnick K, Hartman J, Mansouri K, Minto MS, Nicolas CI, Phillips M, Slattery S, Yoon M, Clewell RA. Evaluating opportunities for advancing the use of alternative methods in risk assessment through the development of fit-for-purpose in vitro assays. Toxicology in Vitro : An International Journal Published in Association With Bibra. PMID 29391263 DOI: 10.1016/j.tiv.2018.01.027  1
2017 Andersen ME, Cruzan G, Black MB, Pendse SN, Dodd D, Bus JS, Sarang S, Banton MI, Waites R, McMullen PD. Assessing molecular initiating events (MIEs), key events (KEs) and modulating factors (MFs) for styrene responses in mouse lungs using whole genome gene expression profiling following 1-day and multi-week exposures. Toxicology and Applied Pharmacology. PMID 28951217 DOI: 10.1016/j.taap.2017.09.015  0.52
2017 Miller MM, McMullen PD, Andersen ME, Clewell RA. Multiple receptors shape the estrogen response pathway and are critical considerations for the future of in vitro-based risk assessment efforts. Critical Reviews in Toxicology. 1-17. PMID 28675057 DOI: 10.1080/10408444.2017.1289150  1
2017 Andersen ME, Black MB, Campbell JL, Pendse SN, Clewell Iii HJ, Pottenger LH, Bus JS, Dodd DE, Kemp DC, McMullen PD. Combining transcriptomics and PBPK modeling indicates a primary role of hypoxia and altered circadian signaling in dichloromethane carcinogenicity in mouse lung and liver. Toxicology and Applied Pharmacology. PMID 28392392 DOI: 10.1016/j.taap.2017.04.002  0.52
2016 Clewell RA, McMullen PD, Adeleye Y, Carmichael PL, Andersen ME. Pathway Based Toxicology and Fit-for-Purpose Assays. Advances in Experimental Medicine and Biology. 856: 205-230. PMID 27671724 DOI: 10.1007/978-3-319-33826-2_8  1
2016 Zhu J, Wang H, Chen F, Fu J, Xu Y, Hou Y, Kou HH, Zhai C, Nelson MB, Zhang Q, Andersen ME, Pi J. An overview of chemical inhibitors of the Nrf2-ARE signaling pathway and their potential applications in cancer therapy. Free Radical Biology & Medicine. PMID 27634172 DOI: 10.1016/j.freeradbiomed.2016.09.010  0.32
2016 Pendse SN, Maertens A, Rosenberg M, Roy D, Fasani RA, Vantangoli MM, Madnick SJ, Boekelheide K, Fornace AJ, Odwin SA, Yager JD, Hartung T, Andersen ME, McMullen PD. Information-dependent enrichment analysis reveals time-dependent transcriptional regulation of the estrogen pathway of toxicity. Archives of Toxicology. PMID 27592001 DOI: 10.1007/s00204-016-1824-6  0.52
2016 Miller MM, Alyea RA, LeSommer C, Doheny DL, Rowley SM, Childs KM, Balbuena P, Ross SM, Dong J, Sun B, Andersen MA, Clewell RA. Development of an in vitro assay measuring uterine-specific estrogenic responses for use in chemical safety assessment. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27503385 DOI: 10.1093/toxsci/kfw152  1
2016 Cote I, Andersen ME, Ankley GT, Barone S, Birnbaum LS, Boekelheide K, Bois FY, Burgoon LD, Chiu WA, Crawford-Brown D, Crofton KM, DeVito M, Devlin RB, Edwards SW, Guyton KZ, et al. The Next Generation of Risk Assessment Multiyear Study- Highlights of Findings, Applications to Risk Assessment and Future Directions. Environmental Health Perspectives. PMID 27091369 DOI: 10.1289/EHP233  0.4
2016 Klapacz J, Pottenger LH, Engelward BP, Heinen CD, Johnson GE, Clewell RA, Carmichael PL, Adeleye Y, Andersen ME. Contributions of DNA repair and damage response pathways to the non-linear genotoxic responses of alkylating agents. Mutation Research. Reviews in Mutation Research. 767: 77-91. PMID 27036068 DOI: 10.1016/j.mrrev.2015.11.001  1
2016 Clewell RA, Andersen ME. Approaches for characterizing threshold dose-response relationships for DNA-damage pathways involved in carcinogenicity in vivo and micronuclei formation in vitro. Mutagenesis. PMID 26846943 DOI: 10.1093/mutage/gev078  1
2015 Fasani RA, Livi CB, Choudhury DR, Kleensang A, Bouhifd M, Pendse SN, McMullen PD, Andersen ME, Hartung T, Rosenberg M. The Human Toxome Collaboratorium: A Shared Environment for Multi-Omic Computational Collaboration within a Consortium. Frontiers in Pharmacology. 6: 322. PMID 26924983 DOI: 10.3389/fphar.2015.00322  0.52
2015 Peng H, Wang H, Xue P, Hou Y, Dong J, Zhou T, Qu W, Peng S, Li J, Carmichael PL, Nelson B, Clewell R, Zhang Q, Andersen ME, Pi J. Suppression of NRF2-ARE activity sensitizes chemotherapeutic agent-induced cytotoxicity in human acute monocytic leukemia cells. Toxicology and Applied Pharmacology. PMID 26708503 DOI: 10.1016/j.taap.2015.12.008  0.52
2015 Zhang Q, Bhattacharya S, Pi J, Clewell RA, Carmichael PL, Andersen ME. Adaptive Posttranslational Control in Cellular Stress Response Pathways and Its Relationship to Toxicity Testing and Safety Assessment. Toxicological Sciences : An Official Journal of the Society of Toxicology. 147: 302-16. PMID 26408567 DOI: 10.1093/toxsci/kfv130  1
2015 Wetmore BA, Wambaugh JF, Allen B, Ferguson SS, Sochaski MA, Setzer RW, Houck KA, Strope CL, Cantwell K, Judson RS, LeCluyse E, Clewell HJ, Thomas RS, Andersen ME. Incorporating High-Throughput Exposure Predictions With Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 26251325 DOI: 10.1093/toxsci/kfv171  0.4
2015 Black MB, Dodd DE, McMullen PD, Pendse S, MacGregor JA, Gollapudi BB, Andersen ME. Using gene expression profiling to evaluate cellular responses in mouse lungs exposed to V2O5 and a group of other mouse lung tumorigens and non-tumorigens. Regulatory Toxicology and Pharmacology : Rtp. 73: 339-47. PMID 26210822 DOI: 10.1016/j.yrtph.2015.07.017  0.52
2015 Andersen ME, McMullen PD, Krewski D. Developing tools for defining and establishing pathways of toxicity. Archives of Toxicology. 89: 809-12. PMID 25851822 DOI: 10.1007/s00204-015-1512-y  0.52
2015 Bouhifd M, Andersen ME, Baghdikian C, Boekelheide K, Crofton KM, Fornace AJ, Kleensang A, Li H, Livi C, Maertens A, McMullen PD, Rosenberg M, Thomas R, Vantangoli M, Yager JD, et al. The human toxome project. Altex. 32: 112-24. PMID 25742299 DOI:  0.52
2015 Zheng H, Fu J, Xue P, Zhao R, Dong J, Liu D, Yamamoto M, Tong Q, Teng W, Qu W, Zhang Q, Andersen ME, Pi J. CNC-bZIP protein Nrf1-dependent regulation of glucose-stimulated insulin secretion. Antioxidants & Redox Signaling. 22: 819-31. PMID 25556857 DOI: 10.1089/ars.2014.6017  0.32
2015 Adeleye Y, Andersen M, Clewell R, Davies M, Dent M, Edwards S, Fowler P, Malcomber S, Nicol B, Scott A, Scott S, Sun B, Westmoreland C, White A, Zhang Q, et al. Implementing Toxicity Testing in the 21st Century (TT21C): Making safety decisions using toxicity pathways, and progress in a prototype risk assessment. Toxicology. 332: 102-11. PMID 24582757 DOI: 10.1016/j.tox.2014.02.007  0.52
2014 Wang S, Zheng W, Liu X, Xue P, Jiang S, Lu D, Zhang Q, He G, Pi J, Andersen ME, Tan H, Qu W. Iodoacetic acid activates Nrf2-mediated antioxidant response in vitro and in vivo. Environmental Science & Technology. 48: 13478-88. PMID 25332096 DOI: 10.1021/es502855x  0.32
2014 Zhang Q, Bhattacharya S, Conolly RB, Clewell HJ, Kaminski NE, Andersen ME. Molecular signaling network motifs provide a mechanistic basis for cellular threshold responses. Environmental Health Perspectives. 122: 1261-70. PMID 25117432 DOI: 10.1289/ehp.1408244  0.32
2014 Clewell RA, Sun B, Adeleye Y, Carmichael P, Efremenko A, McMullen PD, Pendse S, Trask OJ, White A, Andersen ME. Profiling dose-dependent activation of p53-mediated signaling pathways by chemicals with distinct mechanisms of DNA damage. Toxicological Sciences : An Official Journal of the Society of Toxicology. 142: 56-73. PMID 25078064 DOI: 10.1093/toxsci/kfu153  1
2014 Choi K, Pfund WP, Andersen ME, Thomas RS, Clewell HJ, LeCluyse EL. Development of 3D dynamic flow model of human liver and its application to prediction of metabolic clearance of 7-ethoxycoumarin. Tissue Engineering. Part C, Methods. 20: 641-51. PMID 24294911 DOI: 10.1089/ten.TEC.2013.0562  0.4
2014 McMullen PD, Bhattacharya S, Woods CG, Sun B, Yarborough K, Ross SM, Miller ME, McBride MT, LeCluyse EL, Clewell RA, Andersen ME. A map of the PPARα transcription regulatory network for primary human hepatocytes. Chemico-Biological Interactions. 209: 14-24. PMID 24269660 DOI: 10.1016/j.cbi.2013.11.006  1
2014 Li Z, Sun B, Clewell RA, Adeleye Y, Andersen ME, Zhang Q. Dose-response modeling of etoposide-induced DNA damage response. Toxicological Sciences : An Official Journal of the Society of Toxicology. 137: 371-84. PMID 24241721 DOI: 10.1093/toxsci/kft259  1
2014 Kleensang A, Maertens A, Rosenberg M, Fitzpatrick S, Lamb J, Auerbach S, Brennan R, Crofton KM, Gordon B, Fornace AJ, Gaido K, Gerhold D, Haw R, Henney A, Ma'ayan A, ... ... Andersen ME, et al. t4 workshop report: Pathways of Toxicity. Altex. 31: 53-61. PMID 24127042 DOI: 10.14573/altex.1309261  0.52
2013 Chen Y, Xue P, Hou Y, Zhang H, Zheng H, Zhou T, Qu W, Teng W, Zhang Q, Andersen ME, Pi J. Isoniazid suppresses antioxidant response element activities and impairs adipogenesis in mouse and human preadipocytes. Toxicology and Applied Pharmacology. 273: 435-41. PMID 24128855 DOI: 10.1016/j.taap.2013.10.005  0.32
2013 Godoy P, Hewitt NJ, Albrecht U, Andersen ME, Ansari N, Bhattacharya S, Bode JG, Bolleyn J, Borner C, Böttger J, Braeuning A, Budinsky RA, Burkhardt B, Cameron NR, Camussi G, et al. Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME. Archives of Toxicology. 87: 1315-530. PMID 23974980 DOI: 10.1007/s00204-013-1078-5  0.4
2013 Thomas RS, Philbert MA, Auerbach SS, Wetmore BA, Devito MJ, Cote I, Rowlands JC, Whelan MP, Hays SM, Andersen ME, Meek ME, Reiter LW, Lambert JC, Clewell HJ, Stephens ML, et al. Incorporating new technologies into toxicity testing and risk assessment: moving from 21st century vision to a data-driven framework. Toxicological Sciences : An Official Journal of the Society of Toxicology. 136: 4-18. PMID 23958734 DOI: 10.1093/toxsci/kft178  0.4
2013 Lv P, Xue P, Dong J, Peng H, Clewell R, Wang A, Wang Y, Peng S, Qu W, Zhang Q, Andersen ME, Pi J. Keap1 silencing boosts lipopolysaccharide-induced transcription of interleukin 6 via activation of nuclear factor κB in macrophages. Toxicology and Applied Pharmacology. 272: 697-702. PMID 23906629 DOI: 10.1016/j.taap.2013.07.012  0.32
2013 Sun B, Ross SM, Trask OJ, Carmichael PL, Dent M, White A, Andersen ME, Clewell RA. Assessing dose-dependent differences in DNA-damage, p53 response and genotoxicity for quercetin and curcumin. Toxicology in Vitro : An International Journal Published in Association With Bibra. 27: 1877-87. PMID 23764886 DOI: 10.1016/j.tiv.2013.05.015  1
2013 Zhang Q, Bhattacharya S, Andersen ME. Ultrasensitive response motifs: basic amplifiers in molecular signalling networks. Open Biology. 3: 130031. PMID 23615029 DOI: 10.1098/rsob.130031  0.32
2013 Fu J, Zhang Q, Woods CG, Zheng H, Yang B, Qu W, Andersen ME, Pi J. Divergent effects of sulforaphane on basal and glucose-stimulated insulin secretion in β-cells: role of reactive oxygen species and induction of endogenous antioxidants. Pharmaceutical Research. 30: 2248-59. PMID 23468051 DOI: 10.1007/s11095-013-1013-8  0.32
2013 Wetmore BA, Wambaugh JF, Ferguson SS, Li L, Clewell HJ, Judson RS, Freeman K, Bao W, Sochaski MA, Chu TM, Black MB, Healy E, Allen B, Andersen ME, Wolfinger RD, et al. Relative impact of incorporating pharmacokinetics on predicting in vivo hazard and mode of action from high-throughput in vitro toxicity assays. Toxicological Sciences : An Official Journal of the Society of Toxicology. 132: 327-46. PMID 23358191 DOI: 10.1093/toxsci/kft012  0.4
2013 Zhang Q, Kline DE, Bhattacharya S, Crawford RB, Conolly RB, Thomas RS, Andersen ME, Kaminski NE. All-or-none suppression of B cell terminal differentiation by environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicology and Applied Pharmacology. 268: 17-26. PMID 23357550 DOI: 10.1016/j.taap.2013.01.015  0.4
2013 Xue P, Hou Y, Chen Y, Yang B, Fu J, Zheng H, Yarborough K, Woods CG, Liu D, Yamamoto M, Zhang Q, Andersen ME, Pi J. Adipose deficiency of Nrf2 in ob/ob mice results in severe metabolic syndrome. Diabetes. 62: 845-54. PMID 23238296 DOI: 10.2337/db12-0584  0.32
2013 Hou Y, Xue P, Woods CG, Wang X, Fu J, Yarborough K, Qu W, Zhang Q, Andersen ME, Pi J. Association between arsenic suppression of adipogenesis and induction of CHOP10 via the endoplasmic reticulum stress response. Environmental Health Perspectives. 121: 237-43. PMID 23221991 DOI: 10.1289/ehp.1205731  0.32
2013 Andersen ME, McMullen PD, Bhattacharya S. Toxicogenomics for transcription factor-governed molecular pathways: moving on to roles beyond classification and prediction. Archives of Toxicology. 87: 7-11. PMID 23184225 DOI: 10.1007/s00204-012-0980-6  0.52
2013 Thomas RS, Himmelstein MW, Clewell HJ, Yang Y, Healy E, Black MB, Andersen ME. Cross-species transcriptomic analysis of mouse and rat lung exposed to chloroprene. Toxicological Sciences : An Official Journal of the Society of Toxicology. 131: 629-40. PMID 23125180 DOI: 10.1093/toxsci/kfs314  0.4
2013 Clewell RA, Thomas A, Willson G, Creasy DM, Andersen ME. A dose response study to assess effects after dietary administration of diisononyl phthalate (DINP) in gestation and lactation on male rat sexual development. Reproductive Toxicology (Elmsford, N.Y.). 35: 70-80. PMID 22944045 DOI: 10.1016/j.reprotox.2012.07.008  1
2013 Clewell RA, Sochaski M, Edwards K, Creasy DM, Willson G, Andersen ME. Disposition of diiosononyl phthalate and its effects on sexual development of the male fetus following repeated dosing in pregnant rats. Reproductive Toxicology (Elmsford, N.Y.). 35: 56-69. PMID 22813627 DOI: 10.1016/j.reprotox.2012.07.001  1
2012 Bhattacharya S, Shoda LK, Zhang Q, Woods CG, Howell BA, Siler SQ, Woodhead JL, Yang Y, McMullen P, Watkins PB, Andersen ME. Modeling drug- and chemical-induced hepatotoxicity with systems biology approaches. Frontiers in Physiology. 3: 462. PMID 23248599 DOI: 10.3389/fphys.2012.00462  0.32
2012 Campbell JL, Clewell RA, Gentry PR, Andersen ME, Clewell HJ. Physiologically based pharmacokinetic/toxicokinetic modeling. Methods in Molecular Biology (Clifton, N.J.). 929: 439-99. PMID 23007440 DOI: 10.1007/978-1-62703-050-2_18  1
2012 Yang B, Fu J, Zheng H, Xue P, Yarborough K, Woods CG, Hou Y, Zhang Q, Andersen ME, Pi J. Deficiency in the nuclear factor E2-related factor 2 renders pancreatic β-cells vulnerable to arsenic-induced cell damage. Toxicology and Applied Pharmacology. 264: 315-23. PMID 23000044 DOI: 10.1016/j.taap.2012.09.012  0.32
2012 Zhan L, Zhang H, Zhang Q, Woods CG, Chen Y, Xue P, Dong J, Tokar EJ, Xu Y, Hou Y, Fu J, Yarborough K, Wang A, Qu W, Waalkes MP, ... Andersen ME, et al. Regulatory role of KEAP1 and NRF2 in PPARγ expression and chemoresistance in human non-small-cell lung carcinoma cells. Free Radical Biology & Medicine. 53: 758-68. PMID 22684020 DOI: 10.1016/j.freeradbiomed.2012.05.041  0.32
2012 Thomas RS, Black MB, Li L, Healy E, Chu TM, Bao W, Andersen ME, Wolfinger RD. A comprehensive statistical analysis of predicting in vivo hazard using high-throughput in vitro screening. Toxicological Sciences : An Official Journal of the Society of Toxicology. 128: 398-417. PMID 22543276 DOI: 10.1093/toxsci/kfs159  0.4
2012 Zhao R, Hou Y, Zhang Q, Woods CG, Xue P, Fu J, Yarborough K, Guan D, Andersen ME, Pi J. Cross-regulations among NRFs and KEAP1 and effects of their silencing on arsenic-induced antioxidant response and cytotoxicity in human keratinocytes. Environmental Health Perspectives. 120: 583-9. PMID 22476201 DOI: 10.1289/ehp.1104580  0.32
2012 Thomas RS, Clewell HJ, Allen BC, Yang L, Healy E, Andersen ME. Integrating pathway-based transcriptomic data into quantitative chemical risk assessment: a five chemical case study. Mutation Research. 746: 135-43. PMID 22305970 DOI: 10.1016/j.mrgentox.2012.01.007  0.4
2012 Choi K, Joo H, Campbell JL, Clewell RA, Andersen ME, Clewell HJ. In vitro metabolism of di(2-ethylhexyl) phthalate (DEHP) by various tissues and cytochrome P450s of human and rat. Toxicology in Vitro : An International Journal Published in Association With Bibra. 26: 315-22. PMID 22186153 DOI: 10.1016/j.tiv.2011.12.002  1
2012 Hou Y, Xue P, Bai Y, Liu D, Woods CG, Yarborough K, Fu J, Zhang Q, Sun G, Collins S, Chan JY, Yamamoto M, Andersen ME, Pi J. Nuclear factor erythroid-derived factor 2-related factor 2 regulates transcription of CCAAT/enhancer-binding protein β during adipogenesis. Free Radical Biology & Medicine. 52: 462-72. PMID 22138520 DOI: 10.1016/j.freeradbiomed.2011.10.453  0.32
2012 Wetmore BA, Wambaugh JF, Ferguson SS, Sochaski MA, Rotroff DM, Freeman K, Clewell HJ, Dix DJ, Andersen ME, Houck KA, Allen B, Judson RS, Singh R, Kavlock RJ, Richard AM, et al. Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment. Toxicological Sciences : An Official Journal of the Society of Toxicology. 125: 157-74. PMID 21948869 DOI: 10.1093/toxsci/kfr254  0.4
2012 Stephens ML, Barrow C, Andersen ME, Boekelheide K, Carmichael PL, Holsapple MP, Lafranconi M. Accelerating the development of 21st-century toxicology: outcome of a Human Toxicology Project Consortium workshop. Toxicological Sciences : An Official Journal of the Society of Toxicology. 125: 327-34. PMID 21948868 DOI: 10.1093/toxsci/kfr248  0.52
2011 Andersen ME, Clewell HJ, Carmichael PL, Boekelheide K. Can case study approaches speed implementation of the NRC report: "toxicity testing in the 21st century: a vision and a strategy?". Altex. 28: 175-82. PMID 21993955  0.52
2011 Bhattacharya S, Zhang Q, Carmichael PL, Boekelheide K, Andersen ME. Toxicity testing in the 21 century: defining new risk assessment approaches based on perturbation of intracellular toxicity pathways. Plos One. 6: e20887. PMID 21701582 DOI: 10.1371/journal.pone.0020887  0.52
2011 Bhattacharya S, Zhang Q, Andersen ME. A deterministic map of Waddington's epigenetic landscape for cell fate specification. Bmc Systems Biology. 5: 85. PMID 21619617 DOI: 10.1186/1752-0509-5-85  0.32
2011 Xue P, Hou Y, Zhang Q, Woods CG, Yarborough K, Liu H, Sun G, Andersen ME, Pi J. Prolonged inorganic arsenite exposure suppresses insulin-stimulated AKT S473 phosphorylation and glucose uptake in 3T3-L1 adipocytes: involvement of the adaptive antioxidant response. Biochemical and Biophysical Research Communications. 407: 360-5. PMID 21396911 DOI: 10.1016/j.bbrc.2011.03.024  0.32
2011 Thomas RS, Clewell HJ, Allen BC, Wesselkamper SC, Wang NC, Lambert JC, Hess-Wilson JK, Zhao QJ, Andersen ME. Application of transcriptional benchmark dose values in quantitative cancer and noncancer risk assessment. Toxicological Sciences : An Official Journal of the Society of Toxicology. 120: 194-205. PMID 21097997 DOI: 10.1093/toxsci/kfq355  0.4
2010 Boellmann F, Zhang L, Clewell HJ, Schroth GP, Kenyon EM, Andersen ME, Thomas RS. Genome-wide analysis of DNA methylation and gene expression changes in the mouse lung following subchronic arsenate exposure Toxicological Sciences. 117: 404-417. PMID 20667999 DOI: 10.1093/toxsci/kfq225  0.4
2010 Rotroff DM, Wetmore BA, Dix DJ, Ferguson SS, Clewell HJ, Houck KA, Lecluyse EL, Andersen ME, Judson RS, Smith CM, Sochaski MA, Kavlock RJ, Boellmann F, Martin MT, Reif DM, et al. Incorporating human dosimetry and exposure into high-throughput in vitro toxicity screening. Toxicological Sciences : An Official Journal of the Society of Toxicology. 117: 348-58. PMID 20639261 DOI: 10.1093/toxsci/kfq220  0.4
2010 Zhang Q, Bhattacharya S, Andersen ME, Conolly RB. Computational systems biology and dose-response modeling in relation to new directions in toxicity testing. Journal of Toxicology and Environmental Health. Part B, Critical Reviews. 13: 253-76. PMID 20574901 DOI: 10.1080/10937404.2010.483943  0.32
2010 Zhang Q, Bhattacharya S, Kline DE, Crawford RB, Conolly RB, Thomas RS, Kaminski NE, Andersen ME. Stochastic modeling of B lymphocyte terminal differentiation and its suppression by dioxin. Bmc Systems Biology. 4: 40. PMID 20359356 DOI: 10.1186/1752-0509-4-40  0.4
2010 Wetmore BA, Brees DJ, Singh R, Watkins PB, Andersen ME, Loy J, Thomas RS. Quantitative analyses and transcriptomic profiling of circulating messenger RNAs as biomarkers of rat liver injury. Hepatology (Baltimore, Md.). 51: 2127-39. PMID 20235334 DOI: 10.1002/hep.23574  0.4
2010 Bhattacharya S, Conolly RB, Kaminski NE, Thomas RS, Andersen ME, Zhang Q. A bistable switch underlying B-cell differentiation and its disruption by the environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicological Sciences : An Official Journal of the Society of Toxicology. 115: 51-65. PMID 20123757 DOI: 10.1093/toxsci/kfq035  0.4
2010 Fu J, Woods CG, Yehuda-Shnaidman E, Zhang Q, Wong V, Collins S, Sun G, Andersen ME, Pi J. Low-level arsenic impairs glucose-stimulated insulin secretion in pancreatic beta cells: involvement of cellular adaptive response to oxidative stress. Environmental Health Perspectives. 118: 864-70. PMID 20100676 DOI: 10.1289/ehp.0901608  0.32
2010 Clewell RA, Campbell JL, Ross SM, Gaido KW, Clewell HJ, Andersen ME. Assessing the relevance of in vitro measures of phthalate inhibition of steroidogenesis for in vivo response. Toxicology in Vitro : An International Journal Published in Association With Bibra. 24: 327-34. PMID 19699292 DOI: 10.1016/j.tiv.2009.08.003  1
2009 Clewell RA, Pluta L, Thomas RS, Andersen ME. In utero exposure to chloroquine alters sexual development in the male fetal rat. Toxicology and Applied Pharmacology. 237: 366-74. PMID 19393257 DOI: 10.1016/j.taap.2009.04.013  1
2009 Clewell RA, Kremer JJ, Williams CC, Campbell JL, Sochaski MA, Andersen ME, Borghoff SJ. Kinetics of selected di-n-butyl phthalate metabolites and fetal testosterone following repeated and single administration in pregnant rats. Toxicology. 255: 80-90. PMID 19010379 DOI: 10.1016/j.tox.2008.10.010  1
2008 Clewell RA, Kremer JJ, Williams CC, Campbell JL, Andersen ME, Borghoff SJ. Tissue exposures to free and glucuronidated monobutylyphthalate in the pregnant and fetal rat following exposure to di-n-butylphthalate: evaluation with a PBPK model. Toxicological Sciences : An Official Journal of the Society of Toxicology. 103: 241-59. PMID 18344531 DOI: 10.1093/toxsci/kfn054  1
Show low-probability matches.