Jennie B. Leach - Publications

Engineering, Chemical and Biochemical University of Maryland, Baltimore County, Baltimore, MD, United States 
Biomaterials, Neural Tissue Engineering

34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Ghassemi Z, Ruesing S, Leach JB, Zustiak SP. Stability of proteins encapsulated in Michael-type addition polyethylene glycol hydrogels. Biotechnology and Bioengineering. PMID 34606089 DOI: 10.1002/bit.27949  0.625
2020 Simpson LW, Szeto GL, Boukari H, Good TA, Leach JB. Impact of Four Common Hydrogels on Amyloid-β (Aβ) Aggregation and Cytotoxicity: Implications for 3D Models of Alzheimer's Disease. Acs Omega. 5: 20250-20260. PMID 32832778 DOI: 10.1021/acsomega.0c02046  0.759
2020 Simpson LW, Good TA, Leach JB. Protein folding and assembly in confined environments: Implications for protein aggregation in hydrogels and tissues. Biotechnology Advances. 107573. PMID 32512220 DOI: 10.1016/J.Biotechadv.2020.107573  0.336
2020 Simpson LW, Szeto GL, Boukari H, Good TA, Leach JB. Collagen hydrogel confinement of Amyloid-β (Aβ) accelerates aggregation and reduces cytotoxic effects. Acta Biomaterialia. PMID 32464268 DOI: 10.1016/J.Actbio.2020.05.030  0.738
2020 Henry RJ, Ritzel RM, Barrett JP, Doran SJ, Jiao Y, Leach JB, Szeto GL, Wu J, Stoica BA, Faden AI, Loane DJ. Microglial depletion with CSF1R inhibitor during chronic phase of experimental traumatic brain injury reduces neurodegeneration and neurological deficits. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32094203 DOI: 10.1523/Jneurosci.2402-19.2020  0.685
2019 Santos-Cancel M, Simpson LW, Leach JB, White RJ. Direct, Real-Time Detection of Adenosine Triphosphate Release from Astrocytes in 3-Dimensional Culture Using an Integrated Electrochemical, Aptamer-Based Sensor. Acs Chemical Neuroscience. PMID 30754968 DOI: 10.1021/Acschemneuro.9B00033  0.319
2016 Sharee Ghourichaee S, Leach JB. The effect of hypoxia and laminin-rich substrates on the proliferative behavior of human neural stem cells. Journal of Materials Chemistry. B. 4: 3509-3514. PMID 32263384 DOI: 10.1039/C5Tb02701B  0.401
2016 Ghourichaee SS, Powell EM, Leach JB. Enhancement of human neural stem cell self-renewal in 3D hypoxic culture. Biotechnology and Bioengineering. PMID 27869294 DOI: 10.1002/Bit.26224  0.375
2016 Balasubramanian S, Packard JA, Leach JB, Powell EM. Three-dimensional environment sustains morphological heterogeneity and promotes phenotypic progression during astrocyte development. Tissue Engineering. Part A. PMID 27193766 DOI: 10.1089/Ten.Tea.2016.0103  0.571
2015 Leach JB, Shoichet MS. Naturally-derived and bioinspired materials. Journal of Materials Chemistry. B. 3: 7814-7817. PMID 32262897 DOI: 10.1039/C5Tb90130H  0.324
2015 Balasubramanian S, Powell EM, Leach JB. Culturing neurons, glia, and progenitor cells in three- dimensional hydrogels Neuromethods. 93: 91-99. DOI: 10.1007/978-1-4939-2083-9_9  0.499
2015 Balasubramanian S, Powell EM, Leach JB. Investigating cell-ECM interactions and ECM synthesis in three-dimensional hydrogels Neuromethods. 93: 101-108. DOI: 10.1007/978-1-4939-2083-9_10  0.499
2013 Zustiak SP, Pubill S, Ribeiro A, Leach JB. Hydrolytically degradable poly(ethylene glycol) hydrogel scaffolds as a cell delivery vehicle: characterization of PC12 cell response. Biotechnology Progress. 29: 1255-64. PMID 24474590 DOI: 10.1002/Btpr.1761  0.734
2013 Ribeiro A, Balasubramanian S, Hughes D, Vargo S, Powell EM, Leach JB. β1-Integrin cytoskeletal signaling regulates sensory neuron response to matrix dimensionality. Neuroscience. 248: 67-78. PMID 23764511 DOI: 10.1016/J.Neuroscience.2013.05.057  0.663
2013 Wang L, Acosta MA, Leach JB, Carrier RL. Spatially monitoring oxygen level in 3D microfabricated cell culture systems using optical oxygen sensing beads. Lab On a Chip. 13: 1586-92. PMID 23443975 DOI: 10.1039/C3Lc41366G  0.698
2013 Zustiak SP, Wei Y, Leach JB. Protein-hydrogel interactions in tissue engineering: mechanisms and applications. Tissue Engineering. Part B, Reviews. 19: 160-71. PMID 23150926 DOI: 10.1089/Ten.Teb.2012.0458  0.654
2012 Acosta MA, Velasquez M, Williams K, Ross JM, Leach JB. Fluorescent silica particles for monitoring oxygen levels in three-dimensional heterogeneous cellular structures. Biotechnology and Bioengineering. 109: 2663-70. PMID 22511120 DOI: 10.1002/Bit.24530  0.682
2012 Ribeiro A, Vargo S, Powell EM, Leach JB. Substrate three-dimensionality induces elemental morphological transformation of sensory neurons on a physiologic timescale. Tissue Engineering. Part A. 18: 93-102. PMID 21910606 DOI: 10.1089/Ten.Tea.2011.0221  0.58
2011 Zustiak SP, Leach JB. Characterization of protein release from hydrolytically degradable poly(ethylene glycol) hydrogels. Biotechnology and Bioengineering. 108: 197-206. PMID 20803477 DOI: 10.1002/Bit.22911  0.65
2010 Zustiak SP, Boukari H, Leach JB. Solute diffusion and interactions in cross-linked poly(ethylene glycol) hydrogels studied by Fluorescence Correlation Spectroscopy. Soft Matter. 6. PMID 24282439 DOI: 10.1039/C0Sm00111B  0.647
2010 Reeves R, Ribeiro A, Lombardo L, Boyer R, Leach JB. Synthesis and Characterization of Carboxymethylcellulose-Methacrylate Hydrogel Cell Scaffolds. Polymers. 2: 252-264. PMID 22708058 DOI: 10.3390/Polym2030252  0.622
2010 Zustiak SP, Durbal R, Leach JB. Influence of cell-adhesive peptide ligands on poly(ethylene glycol) hydrogel physical, mechanical and transport properties. Acta Biomaterialia. 6: 3404-14. PMID 20385260 DOI: 10.1016/J.Actbio.2010.03.040  0.647
2010 Zustiak SP, Leach JB. Hydrolytically degradable poly(ethylene glycol) hydrogel scaffolds with tunable degradation and mechanical properties. Biomacromolecules. 11: 1348-57. PMID 20355705 DOI: 10.1021/Bm100137Q  0.669
2010 Leach JB, Achyuta AK, Murthy SK. Bridging the Divide between Neuroprosthetic Design, Tissue Engineering and Neurobiology. Frontiers in Neuroengineering. 2: 18. PMID 20161810 DOI: 10.3389/Neuro.16.018.2009  0.321
2010 Ribeiro AS, Powell EM, Leach JB. Neural stem cell differentiation in 2D and 3D microenvironments Ifmbe Proceedings. 32: 422-425. DOI: 10.1007/978-3-642-14998-6_107  0.503
2009 Acosta MA, Ymele-Leki P, Kostov YV, Leach JB. Fluorescent microparticles for sensing cell microenvironment oxygen levels within 3D scaffolds. Biomaterials. 30: 3068-74. PMID 19285719 DOI: 10.1016/J.Biomaterials.2009.02.021  0.707
2009 Williams C, Liao J, Joyce EM, Wang B, Leach JB, Sacks MS, Wong JY. Altered structural and mechanical properties in decellularized rabbit carotid arteries. Acta Biomaterialia. 5: 993-1005. PMID 19135421 DOI: 10.1016/J.Actbio.2008.11.028  0.306
2008 Sarkar S, Isenberg BC, Hodis E, Leach JB, Desai TA, Wong JY. Fabrication of a layered microstructured polycaprolactone construct for 3-D tissue engineering. Journal of Biomaterials Science. Polymer Edition. 19: 1347-62. PMID 18854127 DOI: 10.1163/156856208786052371  0.388
2007 Leach JB, Brown XQ, Jacot JG, Dimilla PA, Wong JY. Neurite outgrowth and branching of PC12 cells on very soft substrates sharply decreases below a threshold of substrate rigidity. Journal of Neural Engineering. 4: 26-34. PMID 17409477 DOI: 10.1088/1741-2560/4/2/003  0.344
2005 Leach JB, Wolinsky JB, Stone PJ, Wong JY. Crosslinked alpha-elastin biomaterials: towards a processable elastin mimetic scaffold. Acta Biomaterialia. 1: 155-64. PMID 16701792 DOI: 10.1016/J.Actbio.2004.12.001  0.307
2005 Leach JB, Schmidt CE. Characterization of protein release from photocrosslinkable hyaluronic acid-polyethylene glycol hydrogel tissue engineering scaffolds. Biomaterials. 26: 125-35. PMID 15207459 DOI: 10.1016/J.Biomaterials.2004.02.018  0.578
2004 Leach JB, Bivens KA, Collins CN, Schmidt CE. Development of photocrosslinkable hyaluronic acid-polyethylene glycol-peptide composite hydrogels for soft tissue engineering. Journal of Biomedical Materials Research. Part A. 70: 74-82. PMID 15174111 DOI: 10.1002/Jbm.A.30063  0.55
2004 Wong JY, Leach JB, Brown XQ. Balance of chemistry, topography, and mechanics at the cell-biomaterial interface: Issues and challenges for assessing the role of substrate mechanics on cell response Surface Science. 570: 119-133. DOI: 10.1016/J.Susc.2004.06.186  0.341
2003 Schmidt CE, Leach JB. Neural tissue engineering: strategies for repair and regeneration. Annual Review of Biomedical Engineering. 5: 293-347. PMID 14527315 DOI: 10.1146/Annurev.Bioeng.5.011303.120731  0.491
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