George Mutwiri - Publications

Affiliations: 
Veterinary Microbiology University of Saskatchewan, Saskatoon, SK, Canada 
Area:
Veterinary Science Biology, Immunology

95 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Awate S, Scruten E, Mutwiri G, Napper S. Kinome Analysis to Define Mechanisms of Adjuvant Action: PCEP Induces Unique Signaling at the Injection Site and Lymph Nodes. Vaccines. 10. PMID 35746541 DOI: 10.3390/vaccines10060927  0.342
2021 Wilson HL, Haddadi A, Mutwiri GK. Vaccine Formulation for Infectious Diseases and Adjuvant Mechanisms of Action. Vaccines. 9. PMID 34207033 DOI: 10.3390/vaccines9060667  0.302
2021 Chaffey A, Hamonic G, Chand D, Mutwiri GK, Wilson HL. The Adjuvants Polyphosphazene (PCEP) and a Combination of Curdlan Plus Leptin Promote a Th17-Type Immune Response to an Intramuscular Vaccine in Mice. Vaccines. 9. PMID 34069081 DOI: 10.3390/vaccines9050507  0.408
2021 Chand DJ, Magiri RB, Wilson HL, Mutwiri GK. Polyphosphazenes as Adjuvants for Animal Vaccines and Other Medical Applications. Frontiers in Bioengineering and Biotechnology. 9: 625482. PMID 33763409 DOI: 10.3389/fbioe.2021.625482  0.358
2020 Magiri RB, Lai KJ, Mutwiri GK, Wilson HL. Experimental PCEP-Adjuvanted Swine Influenza H1N1 Vaccine Induced Strong Immune Responses but Did Not Protect Piglets against Heterologous H3N2 Virus Challenge. Vaccines. 8. PMID 32443540 DOI: 10.3390/Vaccines8020235  0.322
2019 Jimbo S, Griebel PJ, Lai K, Babiuk LA, Mutwiri G. Natural and inducible regulatory B cells are widely distributed in ovine lymphoid tissues. Veterinary Immunology and Immunopathology. 211: 44-48. PMID 31084893 DOI: 10.1016/J.Vetimm.2019.04.005  0.473
2019 Magiri R, Lai K, Huang Y, Mutwiri G, Wilson HL. Innate immune response profiles in pigs injected with vaccine adjuvants polydi(sodium carboxylatoethylphenoxy)phosphazene (PCEP) and Emulsigen. Veterinary Immunology and Immunopathology. 209: 7-16. PMID 30885308 DOI: 10.1016/J.Vetimm.2019.02.004  0.491
2018 Magiri R, Mutwiri G, Wilson HL. Recent advances in experimental polyphosphazene adjuvants and their mechanisms of action. Cell and Tissue Research. PMID 30294754 DOI: 10.1007/S00441-018-2929-4  0.479
2018 Magiri R, Lai K, Chaffey A, Zhou Y, Pyo HM, Gerdts V, Wilson HL, Mutwiri G. Intradermal immunization with inactivated swine influenza virus and adjuvant polydi(sodium carboxylatoethylphenoxy)phosphazene (PCEP) induced humoral and cell-mediated immunity and reduced lung viral titres in pigs. Vaccine. PMID 29454517 DOI: 10.1016/J.Vaccine.2018.02.026  0.45
2016 Magiri RB, Lai K, Chaffey AM, Wilson HL, Berry WE, Szafron ML, Mutwiri GK. Response of immune response genes to adjuvants poly [di(sodium carboxylatoethylphenoxy)phosphazene] (PCEP), CpG oligodeoxynucleotide and emulsigen at intradermal injection site in pigs. Veterinary Immunology and Immunopathology. 175: 57-63. PMID 27269793 DOI: 10.1016/J.Vetimm.2016.05.003  0.479
2016 Backes S, Jäger C, Dembek CJ, Kosinska AD, Bauer T, Stephan AS, Dišlers A, Mutwiri G, Busch DH, Babiuk LA, Gasteiger G, Protzer U. Protein-prime/modified vaccinia virus Ankara vector-boost vaccination overcomes tolerance in high-antigenemic HBV-transgenic mice. Vaccine. 34: 923-32. PMID 26776470 DOI: 10.1016/J.Vaccine.2015.12.060  0.356
2016 Jimbo S, Griebel PJ, Townsend H, Babiuk LA, Mutwiri G. Evidence for the existence of regulatory and effector B cell populations in Peyer's patches of sheep Veterinary Immunology and Immunopathology. 174: 26-34. DOI: 10.1016/J.Vetimm.2016.04.006  0.404
2015 Pasternak JA, Ng SH, Buchanan RM, Mertins S, Mutwiri GK, Gerdts V, Wilson HL. Oral antigen exposure in newborn piglets circumvents induction of oral tolerance in response to intraperitoneal vaccination in later life. Bmc Veterinary Research. 11: 50. PMID 25889479 DOI: 10.1186/S12917-015-0350-8  0.357
2014 Awate S, Eng NF, Gerdts V, Babiuk LA, Mutwiri G. Caspase-1 Dependent IL-1β Secretion and Antigen-Specific T-Cell Activation by the Novel Adjuvant, PCEP. Vaccines. 2: 500-14. PMID 26344742 DOI: 10.3390/Vaccines2030500  0.455
2014 Levast B, Awate S, Babiuk L, Mutwiri G, Gerdts V, van Drunen Littel-van den Hurk S. Vaccine Potentiation by Combination Adjuvants. Vaccines. 2: 297-322. PMID 26344621 DOI: 10.3390/Vaccines2020297  0.47
2014 Dar A, Tikoo S, Potter A, Babiuk LA, Townsend H, Gerdts V, Mutwiri G. CpG-ODNs induced changes in cytokine/chemokines genes expression associated with suppression of infectious bronchitis virus replication in chicken lungs. Veterinary Immunology and Immunopathology. 160: 209-17. PMID 25012000 DOI: 10.1016/J.Vetimm.2014.05.004  0.492
2014 Jimbo S, Griebel PJ, Babiuk L, Mutwiri G. IL-10 secreting CD21+ B cells are present in jejunal Peyer's patches of sheep during fetal development Cell and Tissue Research. 356: 417-425. PMID 24705583 DOI: 10.1007/S00441-014-1803-2  0.473
2014 Awate S, Wilson HL, Singh B, Babiuk LA, Mutwiri G. The adjuvant PCEP induces recruitment of myeloid and lymphoid cells at the injection site and draining lymph node. Vaccine. 32: 2420-7. PMID 24662707 DOI: 10.1016/J.Vaccine.2014.03.014  0.469
2013 Lohmann KL, Lopez AM, Manning ST, Marques FJ, Brownlie R, Allen AL, Sangster AE, Mutwiri G, Gerdts V, Potter A, Townsend HG. Failure of a VapA/CpG oligodeoxynucleotide vaccine to protect foals against experimental Rhocococcus equi pneumonia despite induction of VapA-specific antibody and interferon-γ response. Canadian Journal of Veterinary Research = Revue Canadienne De Recherche Vã©Tã©Rinaire. 77: 161-9. PMID 24101791  0.302
2013 Awate S, Babiuk LA, Mutwiri G. Mechanisms of action of adjuvants. Frontiers in Immunology. 4: 114. PMID 23720661 DOI: 10.3389/Fimmu.2013.00114  0.512
2013 Gerdts V, Mutwiri G, Richards J, van Drunen Littel-van den Hurk S, Potter AA. Carrier molecules for use in veterinary vaccines. Vaccine. 31: 596-602. PMID 23219438 DOI: 10.1016/J.Vaccine.2012.11.067  0.412
2013 Zakhartchouk AN, Mutwiri GK. Toward a new vaccine against measles Molecular Vaccines. 1: 183-191. DOI: 10.1007/978-3-7091-1419-3_9  0.31
2012 Andrianov AK, Mutwiri G. Intradermal immunization using coated microneedles containing an immunoadjuvant. Vaccine. 30: 4355-60. PMID 22682291 DOI: 10.1016/J.Vaccine.2011.09.062  0.386
2012 Awate S, Wilson HL, Lai K, Babiuk LA, Mutwiri G. Activation of adjuvant core response genes by the novel adjuvant PCEP. Molecular Immunology. 51: 292-303. PMID 22521769 DOI: 10.1016/J.Molimm.2012.03.026  0.544
2012 Lobanova LM, Eng NF, Satkunarajah M, Mutwiri GK, Rini JM, Zakhartchouk AN. The recombinant globular head domain of the measles virus hemagglutinin protein as a subunit vaccine against measles. Vaccine. 30: 3061-7. PMID 22406109 DOI: 10.1016/J.Vaccine.2012.02.067  0.398
2012 Dar A, Lai K, Dent D, Potter A, Gerdts V, Babiuk LA, Mutwiri GK. Administration of poly[di(sodium carboxylatoethylphenoxy)]phosphazene (PCEP) as adjuvant activated mixed Th1/Th2 immune responses in pigs. Veterinary Immunology and Immunopathology. 146: 289-95. PMID 22377627 DOI: 10.1016/J.Vetimm.2012.01.021  0.44
2012 Buchanan R, Popowych Y, Dagenais C, Arsic N, Mutwiri GK, Potter AA, Babiuk LA, Griebel PJ, Wilson HL. Interferon-gamma and B-cell Activating Factor (BAFF) promote bovine B cell activation independent of TLR9 and T-cell signaling. Veterinary Immunology and Immunopathology. 145: 453-63. PMID 22264737 DOI: 10.1016/J.Vetimm.2012.01.001  0.344
2012 Mutwiri G. TLR9 agonists: immune mechanisms and therapeutic potential in domestic animals. Veterinary Immunology and Immunopathology. 148: 85-9. PMID 21700345 DOI: 10.1016/J.Vetimm.2011.05.032  0.549
2012 Booth J, Jimbo S, Mutwiri G. Novel B regs down-regulate TLR9-induced cytokine responses in sheep Peyer's patches. Veterinary Immunology and Immunopathology. 148: 157-60. PMID 21596445 DOI: 10.1016/J.Vetimm.2011.04.011  0.727
2012 Wilson HL, Napper S, Mutwiri GK, Littel-van den Hurk SvD, Townsend H, Babiuk LA, Potter AA, Gerdts V. Strategies to Stimulate Innate Immunity for Designing Effective Vaccine Adjuvants Vaccinology: Principles and Practice. 13-28. DOI: 10.1002/9781118345313.ch2  0.348
2011 Garlapati S, Eng NF, Kiros TG, Kindrachuk J, Mutwiri GK, Hancock RE, Halperin SA, Potter AA, Babiuk LA, Gerdts V. Immunization with PCEP microparticles containing pertussis toxoid, CpG ODN and a synthetic innate defense regulator peptide induces protective immunity against pertussis. Vaccine. 29: 6540-8. PMID 21771625 DOI: 10.1016/J.Vaccine.2011.07.009  0.466
2011 Buchanan RM, Popowych Y, Arsic N, Townsend HG, Mutwiri GK, Potter AA, Babiuk LA, Griebel PJ, Wilson HL. B-cell activating factor (BAFF) promotes CpG ODN-induced B cell activation and proliferation. Cellular Immunology. 271: 16-28. PMID 21724179 DOI: 10.1016/J.Cellimm.2011.05.016  0.33
2011 Mutwiri G, Gerdts V, van Drunen Littel-van den Hurk S, Auray G, Eng N, Garlapati S, Babiuk LA, Potter A. Combination adjuvants: the next generation of adjuvants? Expert Review of Vaccines. 10: 95-107. PMID 21162624 DOI: 10.1586/Erv.10.154  0.43
2011 Griebel P, Mutwiri G, Singh B. Innate immunity: complex specificity. Cell and Tissue Research. 343: 1-4. PMID 21107609 DOI: 10.1007/S00441-010-1084-3  0.424
2011 Booth J, Wilson H, Jimbo S, Mutwiri G. Modulation of B cell responses by Toll-like receptors. Cell and Tissue Research. 343: 131-40. PMID 20824286 DOI: 10.1007/S00441-010-1031-3  0.729
2011 Awate S, Eng NF, Mutwiri GK. New alum combinations Novel Immunologic Adjuvants. 17-27. DOI: 10.2217/EBO.11.12  0.405
2010 Garlapati S, Eng NF, Wilson HL, Buchanan R, Mutwiri GK, Babiuk LA, Gerdts V. PCPP (poly[di(carboxylatophenoxy)-phosphazene]) microparticles co-encapsulating ovalbumin and CpG oligo-deoxynucleotides are potent enhancers of antigen specific Th1 immune responses in mice. Vaccine. 28: 8306-14. PMID 21036133 DOI: 10.1016/J.Vaccine.2010.09.080  0.355
2010 Eng NF, Garlapati S, Gerdts V, Babiuk LA, Mutwiri GK. PCEP enhances IgA mucosal immune responses in mice following different immunization routes with influenza virus antigens. Journal of Immune Based Therapies and Vaccines. 8: 4. PMID 20735838 DOI: 10.1186/1476-8518-8-4  0.435
2010 Masic A, Lu X, Li J, Mutwiri GK, Babiuk LA, Brown EG, Zhou Y. Immunogenicity and protective efficacy of an elastase-dependent live attenuated swine influenza virus vaccine administered intranasally in pigs. Vaccine. 28: 7098-108. PMID 20708697 DOI: 10.1016/j.vaccine.2010.08.003  0.338
2010 Nichani AK, Dar MA, Mirakhur KK, Krieg AM, Booth JS, Townsend HG, Potter AA, Babiuk LA, Mutwiri GK. Subcutaneous, but not intratracheal administration of the TLR9 agonist, CpG DNA transiently reduces parainfluenza-3 virus shedding in newborn lambs. Comparative Immunology, Microbiology and Infectious Diseases. 33: e111-7. PMID 20619456 DOI: 10.1016/J.Cimid.2010.06.003  0.677
2010 Booth JS, Arsenault R, Napper S, Griebel PJ, Potter AA, Babiuk LA, Mutwiri GK. TLR9 signaling failure renders Peyer's patch regulatory B cells unresponsive to stimulation with CpG oligodeoxynucleotides. Journal of Innate Immunity. 2: 483-94. PMID 20551621 DOI: 10.1159/000316574  0.699
2010 Shim DH, Ko HJ, Volker G, Potter AA, Mutwiri G, Babiuk LA, Kweon MN. Efficacy of poly[di(sodium carboxylatophenoxy)phosphazene] (PCPP) as mucosal adjuvant to induce protective immunity against respiratory pathogens. Vaccine. 28: 2311-7. PMID 20060944 DOI: 10.1016/J.Vaccine.2009.12.069  0.474
2010 Booth JS, Buza JJ, Potter A, Babiuk LA, Mutwiri GK. Co-stimulation with TLR7/8 and TLR9 agonists induce down-regulation of innate immune responses in sheep blood mononuclear and B cells. Developmental and Comparative Immunology. 34: 572-8. PMID 20051250 DOI: 10.1016/J.Dci.2009.12.018  0.727
2010 Dar A, Nichani A, Lai K, Potter A, Gerdts V, Babiuk LA, Mutwiri G. All three classes of CpG ODNs up-regulate IP-10 gene in pigs. Research in Veterinary Science. 88: 242-50. PMID 19896155 DOI: 10.1016/J.Rvsc.2009.10.003  0.486
2010 Eng NF, Garlapati S, Gerdts V, Potter A, Babiuk LA, Mutwiri GK. The potential of polyphosphazenes for delivery of vaccine antigens and immunotherapeutic agents. Current Drug Delivery. 7: 13-20. PMID 19863483 DOI: 10.2174/156720110790396481  0.36
2009 Andrianov AK, DeCollibus DP, Gillis HA, Kha HH, Marin A, Prausnitz MR, Babiuk LA, Townsend H, Mutwiri G. Poly[di(carboxylatophenoxy)phosphazene] is a potent adjuvant for intradermal immunization. Proceedings of the National Academy of Sciences of the United States of America. 106: 18936-41. PMID 19864632 DOI: 10.1073/Pnas.0908842106  0.451
2009 Dar A, Potter A, Tikoo S, Gerdts V, Lai K, Babiuk LA, Mutwiri G. CpG oligodeoxynucleotides activate innate immune response that suppresses infectious bronchitis virus replication in chicken embryos. Avian Diseases. 53: 261-7. PMID 19630234 DOI: 10.1637/8560-121808-Reg.1  0.537
2009 Masic A, Booth JS, Mutwiri GK, Babiuk LA, Zhou Y. Elastase-dependent live attenuated swine influenza A viruses are immunogenic and confer protection against swine influenza A virus infection in pigs. Journal of Virology. 83: 10198-210. PMID 19625412 DOI: 10.1128/Jvi.00926-09  0.649
2009 Brownlie R, Zhu J, Allan B, Mutwiri GK, Babiuk LA, Potter A, Griebel P. Chicken TLR21 acts as a functional homologue to mammalian TLR9 in the recognition of CpG oligodeoxynucleotides. Molecular Immunology. 46: 3163-70. PMID 19573927 DOI: 10.1016/J.Molimm.2009.06.002  0.405
2009 Taghavi A, Allan B, Mutwiri G, Foldvari M, Van Kessel A, Willson P, Babiuk L, Potter A, Gomis S. Enhancement of immunoprotective effect of CpG-ODN by formulation with polyphosphazenes against E. coli septicemia in neonatal chickens. Current Drug Delivery. 6: 76-82. PMID 19418959 DOI: 10.2174/156720109787048221  0.303
2009 Booth JS, Griebel PJ, Babiuk LA, Mutwiri GK. A novel regulatory B-cell population in sheep Peyer's patches spontaneously secretes IL-10 and downregulates TLR9-induced IFNalpha responses. Mucosal Immunology. 2: 265-75. PMID 19262501 DOI: 10.1038/Mi.2009.6  0.725
2009 Mutwiri G, van Drunen Littel-van den Hurk S, Babiuk LA. Approaches to enhancing immune responses stimulated by CpG oligodeoxynucleotides. Advanced Drug Delivery Reviews. 61: 226-32. PMID 19162103 DOI: 10.1016/J.Addr.2008.12.004  0.492
2009 Gaertner FH, Babiuk LA, Mutwiri G, Armstrong JM, Griebel PJ. Amended recombinant cells (ARCs) expressing bovine IFN-gamma: an economical and highly effective adjuvant system. Vaccine. 27: 1377-85. PMID 19150640 DOI: 10.1016/J.Vaccine.2008.12.049  0.467
2009 Garlapati S, Facci M, Polewicz M, Strom S, Babiuk LA, Mutwiri G, Hancock RE, Elliott MR, Gerdts V. Strategies to link innate and adaptive immunity when designing vaccine adjuvants. Veterinary Immunology and Immunopathology. 128: 184-91. PMID 19042032 DOI: 10.1016/J.Vetimm.2008.10.298  0.507
2009 Zhu J, Brownlie R, Liu Q, Babiuk LA, Potter A, Mutwiri GK. Characterization of bovine Toll-like receptor 8: ligand specificity, signaling essential sites and dimerization. Molecular Immunology. 46: 978-90. PMID 18995910 DOI: 10.1016/j.molimm.2008.09.024  0.307
2009 Eng NF, Garlapati S, Lai K, Gerdts V, Mutwiri GK. Polyphosphazenes Enhance Mucosal and Systemic Immune Responses in Mice Immunized Intranasally with Influenza Antigens The Open Vaccine Journal. 2: 134-143. DOI: 10.2174/1875035400902010134  0.454
2009 Dar A, Allan B, Gomis S, Potter A, Mutwiri G. Immunotherapeutic potential of CpG oligonucleotides in chickens Journal of Poultry Science. 46: 69-80. DOI: 10.2141/Jpsa.46.69  0.493
2009 Buza J, Benjamin P, Zhu J, Krieg AM, Babiuk LA, Mutwiri GK. CD14+ cells are required for TLR7/8 ligand-induced IL-12 and IFN-γ responses in bovine blood mononuclear cells Veterinary Immunology and Immunopathology. 128: 312. DOI: 10.1016/j.vetimm.2008.10.219  0.353
2008 Taghavi A, Allan B, Mutwiri G, Van Kessel A, Willson P, Babiuk L, Potter A, Gomis S. Protection of neonatal broiler chicks against Salmonella Typhimurium septicemia by DNA containing CpG motifs. Avian Diseases. 52: 398-406. PMID 18939626 DOI: 10.1637/8196-121907-Reg  0.348
2008 Buza J, Benjamin P, Zhu J, Wilson HL, Lipford G, Krieg AM, Babiuk LA, Mutwiri GK. CD14+ cells are required for IL-12 response in bovine blood mononuclear cells activated with Toll-like receptor (TLR) 7 and TLR8 ligands. Veterinary Immunology and Immunopathology. 126: 273-82. PMID 18789542 DOI: 10.1016/J.Vetimm.2008.08.001  0.49
2008 Babiuk S, Asper DJ, Rogan D, Mutwiri GK, Potter AA. Subcutaneous and intranasal immunization with type III secreted proteins can prevent colonization and shedding of Escherichia coli O157:H7 in mice. Microbial Pathogenesis. 45: 7-11. PMID 18487034 DOI: 10.1016/j.micpath.2008.01.005  0.318
2008 Zhu J, Lai K, Brownile R, Babiuk LA, Mutwiri GK. Porcine TLR8 and TLR7 are both activated by a selective TLR7 ligand, imiquimod. Molecular Immunology. 45: 3238-43. PMID 18439678 DOI: 10.1016/j.molimm.2008.02.028  0.326
2008 Mutwiri G, Benjamin P, Soita H, Babiuk LA. Co-administration of polyphosphazenes with CpG oligodeoxynucleotides strongly enhances immune responses in mice immunized with Hepatitis B virus surface antigen. Vaccine. 26: 2680-8. PMID 18430493 DOI: 10.1016/J.Vaccine.2008.03.031  0.573
2008 Patel BA, Gomis S, Dar A, Willson PJ, Babiuk LA, Potter A, Mutwiri G, Tikoo SK. Oligodeoxynucleotides containing CpG motifs (CpG-ODN) predominantly induce Th1-type immune response in neonatal chicks. Developmental and Comparative Immunology. 32: 1041-9. PMID 18395255 DOI: 10.1016/J.Dci.2008.02.007  0.441
2008 Dar A, Nichani AK, Benjamin P, Lai K, Soita H, Krieg AM, Potter A, Babiuk LA, Mutwiri GK. Attenuated cytokine responses in porcine lymph node cells stimulated with CpG DNA are associated with low frequency of IFNalpha-producing cells and TLR9 mRNA expression. Veterinary Immunology and Immunopathology. 123: 324-36. PMID 18367252 DOI: 10.1016/j.vetimm.2008.02.007  0.418
2008 Forsbach A, Nemorin JG, Montino C, Müller C, Samulowitz U, Vicari AP, Jurk M, Mutwiri GK, Krieg AM, Lipford GB, Vollmer J. Identification of RNA sequence motifs stimulating sequence-specific TLR8-dependent immune responses. Journal of Immunology (Baltimore, Md. : 1950). 180: 3729-38. PMID 18322178  0.387
2008 Mapletoft JW, Oumouna M, Kovacs-Nolan J, Latimer L, Mutwiri G, Babiuk LA, van Drunen Littel-van den Hurk S. Intranasal immunization of mice with a formalin-inactivated bovine respiratory syncytial virus vaccine co-formulated with CpG oligodeoxynucleotides and polyphosphazenes results in enhanced protection. The Journal of General Virology. 89: 250-60. PMID 18089749 DOI: 10.1099/Vir.0.83300-0  0.526
2008 Mutwiri G, Babiuk LA. Potential of Polyphosphazenes in Modulating Vaccine-Induced Immune Responses: II. Investigations in Large Animals Polyphosphazenes For Biomedical Applications. 77-84. DOI: 10.1002/9780470478882.ch5  0.369
2008 Mutwiri G, Benjamin P, Andrianov AK, Babiuk LA. Potential of Polyphosphazenes in Modulating Vaccine-Induced Immune Responses: I. Investigations in Mice Polyphosphazenes For Biomedical Applications. 65-75. DOI: 10.1002/9780470478882.ch4  0.37
2007 Mutwiri G, Gerdts V, Lopez M, Babiuk LA. Innate immunity and new adjuvants Oie Revue Scientifique Et Technique. 26: 147-156. PMID 17633299 DOI: 10.20506/Rst.26.1.1731  0.45
2007 Ellis J, Gow S, West K, Waldner C, Rhodes C, Mutwiri G, Rosenberg H. Response of calves to challenge exposure with virulent bovine respiratory syncytial virus following intranasal administration of vaccines formulated for parenteral administration. Journal of the American Veterinary Medical Association. 230: 233-43. PMID 17223757 DOI: 10.2460/Javma.230.2.233  0.335
2007 Nichani AK, Dar MA, Krieg AM, Mirakhur KK, Kaushik RS, Griebel PJ, Manuja A, Townsend HG, Babiuk LA, Mutwiri GK. Systemic innate immune responses following intrapulmonary delivery of CpG oligodeoxynucleotides in sheep. Veterinary Immunology and Immunopathology. 115: 357-68. PMID 17194483 DOI: 10.1016/j.vetimm.2006.11.013  0.38
2007 Mutwiri G, Benjamin P, Soita H, Townsend H, Yost R, Roberts B, Andrianov AK, Babiuk LA. Poly[di(sodium carboxylatoethylphenoxy)phosphazene] (PCEP) is a potent enhancer of mixed Th1/Th2 immune responses in mice immunized with influenza virus antigens. Vaccine. 25: 1204-13. PMID 17140708 DOI: 10.1016/J.Vaccine.2006.10.011  0.526
2007 Booth JS, Nichani AK, Benjamin P, Dar A, Krieg AM, Babiuk LA, Mutwiri GK. Innate immune responses induced by classes of CpG oligodeoxynucleotides in ovine lymph node and blood mononuclear cells. Veterinary Immunology and Immunopathology. 115: 24-34. PMID 17067685 DOI: 10.1016/J.Vetimm.2006.09.008  0.702
2007 Zakhartchouk AN, Sharon C, Satkunarajah M, Auperin T, Viswanathan S, Mutwiri G, Petric M, See RH, Brunham RC, Finlay BB, Cameron C, Kelvin DJ, Cochrane A, Rini JM, Babiuk LA. Immunogenicity of a receptor-binding domain of SARS coronavirus spike protein in mice: implications for a subunit vaccine. Vaccine. 25: 136-43. PMID 16919855 DOI: 10.1016/J.Vaccine.2006.06.084  0.416
2006 Lopez AM, Hecker R, Mutwiri G, van Drunen Littel-van den Hurk S, Babiuk LA, Townsend HGG. Formulation with CpG ODN enhances antibody responses to an equine influenza virus vaccine Veterinary Immunology and Immunopathology. 114: 103-110. PMID 16950519 DOI: 10.1016/J.Vetimm.2006.07.013  0.406
2006 Wilson HL, Dar A, Napper SK, Marianela Lopez A, Babiuk LA, Mutwiri GK. Immune mechanisms and therapeutic potential of CpG oligodeoxynucleotides. International Reviews of Immunology. 25: 183-213. PMID 16818371 DOI: 10.1080/08830180600785868  0.4
2006 Gerdts V, Mutwiri GK, Tikoo SK, Babiuk LA. Mucosal delivery of vaccines in domestic animals. Veterinary Research. 37: 487-510. PMID 16611560 DOI: 10.1051/Vetres:2006012  0.338
2006 Nichani AK, Mena A, Kaushik RS, Mutwiri GK, Townsend HG, Hecker R, Krieg AM, Babiuk LA, Griebel PJ. Stimulation of innate immune responses by CpG oligodeoxynucleotide in newborn lambs can reduce bovine herpesvirus-1 shedding. Oligonucleotides. 16: 58-67. PMID 16584295 DOI: 10.1089/oli.2006.16.58  0.456
2005 Mutwiri G, Bowersock TL, Babiuk LA. Microparticles for oral delivery of vaccines. Expert Opinion On Drug Delivery. 2: 791-806. PMID 16296779 DOI: 10.1517/17425247.2.5.791  0.346
2005 Griebel PJ, Brownlie R, Manuja A, Nichani A, Mookherjee N, Popowych Y, Mutwiri G, Hecker R, Babiuk LA. Bovine toll-like receptor 9: a comparative analysis of molecular structure, function and expression. Veterinary Immunology and Immunopathology. 108: 11-6. PMID 16098606 DOI: 10.1016/J.Vetimm.2005.07.012  0.508
2004 Mutwiri GK, Nichani AK, Babiuk S, Babiuk LA. Strategies for enhancing the immunostimulatory effects of CpG oligodeoxynucleotides. Journal of Controlled Release : Official Journal of the Controlled Release Society. 97: 1-17. PMID 15147800 DOI: 10.1016/j.jconrel.2004.02.022  0.41
2004 Nichani AK, Mena A, Popowych Y, Dent D, Townsend HGG, Mutwiri GK, Hecker R, Babiuk LA, Griebel PJ. In vivo immunostimulatory effects of CpG oligodeoxynucleotide in cattle and sheep Veterinary Immunology and Immunopathology. 98: 17-29. PMID 15127838 DOI: 10.1016/j.vetimm.2003.10.001  0.347
2004 Nichani AK, Kaushik RS, Mena A, Popowych Y, Dent D, Townsend HG, Mutwiri G, Hecker R, Babiuk LA, Griebel PJ. CpG oligodeoxynucleotide induction of antiviral effector molecules in sheep. Cellular Immunology. 227: 24-37. PMID 15051512 DOI: 10.1016/J.Cellimm.2004.01.004  0.411
2003 Mena A, Nichani AK, Popowych Y, Ioannou XP, Godson DL, Mutwiri GK, Hecker R, Babiuk LA, Griebel P. Bovine and ovine blood mononuclear leukocytes differ markedly in innate immune responses induced by Class A and Class B CpG-oligodeoxynucleotide. Oligonucleotides. 13: 245-59. PMID 15000839 DOI: 10.1089/154545703322460621  0.415
2003 Mena A, Nichani AK, Popowych Y, Godson DL, Dent D, Townsend HG, Mutwiri GK, Hecker R, Babiuk LA, Griebel P. Innate immune responses induced by CpG oligodeoxyribonucleotide stimulation of ovine blood mononuclear cells. Immunology. 110: 250-7. PMID 14511239 DOI: 10.1046/j.1365-2567.2003.01722.x  0.453
2003 Ioannou XP, Griebel P, Mena A, Gomis SM, Godson DL, Mutwiri G, Hecker R, Babiuk LA, Van Drunen Littel-Van Den Hurk S. Safety of CpG oligodeoxynucleotides in veterinary species Antisense and Nucleic Acid Drug Development. 13: 157-167. PMID 12954116  0.304
2003 Mutwiri G, Pontarollo R, Babiuk S, Griebel P, Van Drunen Littel-Van Den Hurk S, Mena A, Tsang C, Alcon V, Nichani A, Ioannou X, Gomis S, Townsend H, Hecker R, Potter A, Babiuk LA. Biological activity of immunostimulatory CpG DNA motifs in domestic animals Veterinary Immunology and Immunopathology. 91: 89-103. PMID 12543546 DOI: 10.1016/S0165-2427(02)00246-5  0.508
2002 Kim B, Bowersock T, Griebel P, Kidane A, Babiuk LA, Sanchez M, Attah-Poku S, Kaushik RS, Mutwiri GK. Mucosal immune responses following oral immunization with rotavirus antigens encapsulated in alginate microspheres. Journal of Controlled Release : Official Journal of the Controlled Release Society. 85: 191-202. PMID 12480324 DOI: 10.1016/S0168-3659(02)00280-8  0.399
2002 Mutwiri G, Bowersock T, Kidane A, Sanchez M, Gerdts V, Babiuk LA, Griebel P. Induction of mucosal immune responses following enteric immunization with antigen delivered in alginate microspheres. Veterinary Immunology and Immunopathology. 87: 269-76. PMID 12072246 DOI: 10.1016/S0165-2427(02)00052-1  0.523
2001 Gerdts V, Uwiera RR, Mutwiri GK, Wilson DJ, Bowersock T, Kidane A, Babiuk LA, Griebel PJ. Multiple intestinal 'loops' provide an in vivo model to analyse multiple mucosal immune responses. Journal of Immunological Methods. 256: 19-33. PMID 11516752 DOI: 10.1016/S0022-1759(01)00429-X  0.393
2000 Mutwiri G, Bateman C, Baca-Estrada ME, Snider M, Griebel P. Induction of immune responses in newborn lambs following enteric immunization with a human adenovirus vaccine vector. Vaccine. 19: 1284-93. PMID 11137268 DOI: 10.1016/S0264-410X(00)00230-9  0.521
2000 Reddy PS, Idamakanti N, Pyne C, Zakhartchouk AN, Godson DL, Papp Z, Baca-Estrada ME, Babiuk LA, Mutwiri GK, Tikoo SK. The immunogenicity and efficacy of replication-defective and replication-competent bovine adenovirus-3 expressing bovine herpesvirus-1 glycoprotein gD in cattle Veterinary Immunology and Immunopathology. 76: 257-268. PMID 11044558 DOI: 10.1016/S0165-2427(00)00217-8  0.378
1999 Mutwiri G, Watts T, Lew L, Beskorwayne T, Papp Z, Baca-Estrada ME, Griebel P. Ileal and jejunal Peyer's patches play distinct roles in mucosal immunity of sheep Immunology. 97: 455-461. PMID 10447767 DOI: 10.1046/J.1365-2567.1999.00791.X  0.5
1999 Zakhartchouk AN, Pyne C, Mutwiri GK, Papp Z, Baca-Estrada ME, Griebel P, Babiuk LA, Tikoo SK. Mucosal immunization of calves with recombinant bovine adenovirus-3: Induction of protective immunity to bovine herpesvirus-1 Journal of General Virology. 80: 1263-1269. PMID 10355773 DOI: 10.1099/0022-1317-80-5-1263  0.377
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