Garnett Kelsoe - Publications

Affiliations: 
Immunology Duke University, Durham, NC 
Area:
Biochemistry

199 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Kuraoka M, Burn Aschner C, Windsor IW, Mahant Mahant A, Garforth SJ, Kong SL, Achkar JM, Almo SC, Kelsoe G, Herold BC. A non-neutralizing glycoprotein B monoclonal antibody protects against herpes simplex virus disease in mice. The Journal of Clinical Investigation. PMID 36454639 DOI: 10.1172/JCI161968  0.732
2022 Kuraoka M, Curtis NC, Watanabe A, Tanno H, Shin S, Ye K, Macdonald E, Lavidor O, Kong S, Von Holle T, Windsor I, Ippolito GC, Georgiou G, Walter EB, Kelsoe G, et al. Infant Antibody Repertoires during the First Two Years of Influenza Vaccination. Mbio. e0254622. PMID 36314798 DOI: 10.1128/mbio.02546-22  0.705
2022 Kuraoka M, Yeh CH, Bajic G, Kotaki R, Song S, Windsor I, Harrison SC, Kelsoe G. Recall of B cell memory depends on relative locations of prime and boost immunization. Science Immunology. 7: eabn5311. PMID 35522723 DOI: 10.1126/sciimmunol.abn5311  0.751
2022 Yeh CH, Finney J, Okada T, Kurosaki T, Kelsoe G. Primary germinal center-resident T follicular helper cells are a physiologically distinct subset of CXCR5PD-1 T follicular helper cells. Immunity. 55: 272-289.e7. PMID 35081372 DOI: 10.1016/j.immuni.2021.12.015  0.304
2021 Finney J, Kelsoe G. Continuous Culture of Mouse Primary B Lymphocytes by Forced Expression of . Journal of Immunology (Baltimore, Md. : 1950). 207: 1478-1492. PMID 34389622 DOI: 10.4049/jimmunol.2100172  0.36
2021 Song S, Manook M, Kwun J, Jackson AM, Knechtle SJ, Kelsoe G. Allo-Specific Humoral Responses: New Methods for Screening Donor-Specific Antibody and Characterization of HLA-Specific Memory B Cells. Frontiers in Immunology. 12: 705140. PMID 34326847 DOI: 10.3389/fimmu.2021.705140  0.356
2021 McCarthy KR, Lee J, Watanabe A, Kuraoka M, Robinson-McCarthy LR, Georgiou G, Kelsoe G, Harrison SC. A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface. Mbio. e0114421. PMID 34060327 DOI: 10.1128/mBio.01144-21  0.707
2021 Williams WB, Meyerhoff RR, Edwards RJ, Li H, Manne K, Nicely NI, Henderson R, Zhou Y, Janowska K, Mansouri K, Gobeil S, Evangelous T, Hora B, Berry M, Abuahmad AY, ... ... Kelsoe G, et al. Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell. PMID 34019795 DOI: 10.1016/j.cell.2021.04.042  0.304
2020 Finney J, Kelsoe G. Ideal Vaccines: Balancing B Cell Recruitment and Differentiation. Immunity. 53: 473-475. PMID 32937146 DOI: 10.1016/J.Immuni.2020.08.008  0.429
2020 Nojima T, Reynolds AE, Kitamura D, Kelsoe G, Kuraoka M. Tracing Self-Reactive B Cells in Normal Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 32414809 DOI: 10.4049/Jimmunol.1901015  0.774
2020 Bajic G, Maron MJ, Caradonna TM, Tian M, Mermelstein A, Fera D, Kelsoe G, Kuraoka M, Schmidt A. Structure-guided molecular grafting of a complex broadly neutralizing viral epitope. Acs Infectious Diseases. PMID 32267676 DOI: 10.1021/Acsinfecdis.0C00008  0.732
2020 Bradley T, Kuraoka M, Yeh CH, Tian M, Chen H, Cain DW, Chen X, Cheng C, Ellebedy AH, Parks R, Barr M, Sutherland LL, Scearce RM, Bowman CM, Bouton-Verville H, ... ... Kelsoe G, et al. Immune checkpoint modulation enhances HIV-1 antibody induction. Nature Communications. 11: 948. PMID 32075963 DOI: 10.1038/S41467-020-14670-W  0.809
2019 Finney J, Yang G, Kuraoka M, Song S, Nojima T, Verkoczy L, Kitamura D, Haynes BF, Kelsoe G. Cross-Reactivity to Kynureninase Tolerizes B Cells That Express the HIV-1 Broadly Neutralizing Antibody 2F5. Journal of Immunology (Baltimore, Md. : 1950). PMID 31732530 DOI: 10.4049/Jimmunol.1900069  0.759
2019 Onodera T, Hashi K, Shukla RK, Miki M, Takai-Todaka R, Fujimoto A, Kuraoka M, Miyoshi T, Kobayashi K, Hasegawa H, Ato M, Kelsoe G, Katayama K, Takahashi Y. Immune-Focusing Properties of Virus-like Particles Improve Protective IgA Responses. Journal of Immunology (Baltimore, Md. : 1950). PMID 31704880 DOI: 10.4049/Jimmunol.1900481  0.778
2019 Finney J, Watanabe A, Kelsoe G, Kuraoka M. Minding the gap: The impact of B-cell tolerance on the microbial antibody repertoire. Immunological Reviews. PMID 31559648 DOI: 10.1111/Imr.12805  0.78
2019 Adachi Y, Tonouchi K, Nithichanon A, Kuraoka M, Watanabe A, Shinnakasu R, Asanuma H, Ainai A, Ohmi Y, Yamamoto T, Ishii KJ, Hasegawa H, Takeyama H, Lertmemongkolchai G, Kurosaki T, ... ... Kelsoe G, et al. Exposure of an occluded hemagglutinin epitope drives selection of a class of cross-protective influenza antibodies. Nature Communications. 10: 3883. PMID 31462639 DOI: 10.1038/S41467-019-11821-6  0.799
2019 Bajic G, Maron MJ, Adachi Y, Onodera T, McCarthy KR, McGee CE, Sempowski GD, Takahashi Y, Kelsoe G, Kuraoka M, Schmidt AG. Influenza Antigen Engineering Focuses Immune Responses to a Subdominant but Broadly Protective Viral Epitope. Cell Host & Microbe. PMID 31104946 DOI: 10.1016/J.Chom.2019.04.003  0.809
2019 Watanabe A, McCarthy KR, Kuraoka M, Schmidt AG, Adachi Y, Onodera T, Tonouchi K, Caradonna TM, Bajic G, Song S, McGee CE, Sempowski GD, Feng F, Urick P, Kepler TB, ... ... Kelsoe G, et al. Antibodies to a Conserved Influenza Head Interface Epitope Protect by an IgG Subtype-Dependent Mechanism. Cell. 177: 1124-1135.e16. PMID 31100267 DOI: 10.1016/J.Cell.2019.03.048  0.797
2019 Watanabe A, Su KY, Kuraoka M, Yang G, Reynolds AE, Schmidt AG, Harrison SC, Haynes BF, St Clair EW, Kelsoe G. Self-tolerance curtails the B cell repertoire to microbial epitopes. Jci Insight. 4. PMID 31092727 DOI: 10.1172/Jci.Insight.122551  0.767
2019 Bajic G, van der Poel CE, Kuraoka M, Schmidt AG, Carroll MC, Kelsoe G, Harrison SC. Autoreactivity profiles of influenza hemagglutinin broadly neutralizing antibodies. Scientific Reports. 9: 3492. PMID 30837606 DOI: 10.1038/S41598-019-40175-8  0.715
2018 Bonsignori M, Scott E, Wiehe K, Easterhoff D, Alam SM, Hwang KK, Cooper M, Xia SM, Zhang R, Montefiori DC, Henderson R, Nie X, Kelsoe G, Moody MA, Chen X, et al. Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier. Immunity. PMID 30552024 DOI: 10.1016/J.Immuni.2018.10.015  0.423
2018 Kuraoka M, Meffre E, Kelsoe G. The First B-Cell Tolerance Checkpoint in Mice and Humans: Control by AID. Advances in Immunology. 139: 51-92. PMID 30249334 DOI: 10.1016/Bs.Ai.2018.04.001  0.78
2018 Finney J, Kelsoe G. Poly- and autoreactivity of HIV-1 bNAbs: implications for vaccine design. Retrovirology. 15: 53. PMID 30055635 DOI: 10.1186/S12977-018-0435-0  0.392
2018 Finney J, Yeh CH, Kelsoe G, Kuraoka M. Germinal center responses to complex antigens. Immunological Reviews. 284: 42-50. PMID 29944756 DOI: 10.1111/Imr.12661  0.772
2018 Yeh CH, Nojima T, Kuraoka M, Kelsoe G. Germinal center entry not selection of B cells is controlled by peptide-MHCII complex density. Nature Communications. 9: 928. PMID 29500348 DOI: 10.1038/S41467-018-03382-X  0.769
2018 McCarthy KR, Watanabe A, Kuraoka M, Do KT, McGee CE, Sempowski GD, Kepler TB, Schmidt AG, Kelsoe G, Harrison SC. Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses Are Abundant in Adult Human Repertoires. Immunity. 48: 174-184.e9. PMID 29343437 DOI: 10.1016/J.Immuni.2017.12.009  0.734
2017 Silva M, Nguyen TH, Philbrook P, Chu M, Sears O, Hatfield S, Abbott RK, Kelsoe G, Sitkovsky MV. Targeted Elimination of Immunodominant B Cells Drives the Germinal Center Reaction toward Subdominant Epitopes. Cell Reports. 21: 3672-3680. PMID 29281817 DOI: 10.1016/J.Celrep.2017.12.014  0.49
2017 Williams WB, Zhang J, Jiang C, Nicely NI, Fera D, Luo K, Moody MA, Liao HX, Alam SM, Kepler TB, Ramesh A, Wiehe K, Holland JA, Bradley T, Vandergrift N, ... ... Kelsoe G, et al. Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations. Nature Communications. 8: 1732. PMID 29170366 DOI: 10.1038/S41467-017-01336-3  0.459
2017 Williams LD, Ofek G, Schätzle S, McDaniel JR, Lu X, Nicely NI, Wu L, Lougheed CS, Bradley T, Louder MK, McKee K, Bailer RT, O'Dell S, Georgiev IS, Seaman MS, ... ... Kelsoe G, et al. Potent and broad HIV-neutralizing antibodies in memory B cells and plasma. Science Immunology. 2. PMID 28783671 DOI: 10.1126/Sciimmunol.Aal2200  0.431
2017 Kelsoe G, Haynes BF. What Are the Primary Limitations in B-Cell Affinity Maturation, and How Much Affinity Maturation Can We Drive with Vaccination? Breaking through Immunity's Glass Ceiling. Cold Spring Harbor Perspectives in Biology. PMID 28630077 DOI: 10.1101/Cshperspect.A029397  0.359
2017 Takahashi Y, Kelsoe G. Role of germinal centers for the induction of broadly-reactive memory B cells. Current Opinion in Immunology. 45: 119-125. PMID 28355576 DOI: 10.1016/J.Coi.2017.03.002  0.671
2017 Bonsignori M, Kreider EF, Fera D, Meyerhoff RR, Bradley T, Wiehe K, Alam SM, Aussedat B, Walkowicz WE, Hwang KK, Saunders KO, Zhang R, Gladden MA, Monroe A, Kumar A, ... ... Kelsoe G, et al. Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies. Science Translational Medicine. 9. PMID 28298420 DOI: 10.1126/Scitranslmed.Aai7514  0.432
2017 Kuraoka M, Snowden PB, Nojima T, Verkoczy L, Haynes BF, Kitamura D, Kelsoe G. BCR and Endosomal TLR Signals Synergize to Increase AID Expression and Establish Central B Cell Tolerance. Cell Reports. 18: 1627-1635. PMID 28199836 DOI: 10.1016/J.Celrep.2017.01.050  0.804
2017 Kelsoe G, Haynes BF. Host controls of HIV broadly neutralizing antibody development. Immunological Reviews. 275: 79-88. PMID 28133807 DOI: 10.1111/Imr.12508  0.433
2016 Moody MA, Pedroza-Pacheco I, Vandergrift NA, Chui C, Lloyd KE, Parks R, Soderberg KA, Ogbe AT, Cohen MS, Liao HX, Gao F, McMichael AJ, Montefiori DC, Verkoczy L, Kelsoe G, et al. Immune perturbations in HIV-1-infected individuals who make broadly neutralizing antibodies. Science Immunology. 1: aag0851. PMID 28783677 DOI: 10.1126/Sciimmunol.Aag0851  0.348
2016 Wiehe K, Nicely NI, Lockwood B, Kuraoka M, Anasti K, Arora S, Bowman CM, Stolarchuk C, Parks R, Lloyd KE, Xia SM, Duffy R, Shen X, Kyratsous CA, Macdonald LE, ... ... Kelsoe G, et al. Immunodominance of Antibody Recognition of the HIV Envelope V2 Region in Ig-Humanized Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 28011932 DOI: 10.4049/Jimmunol.1601640  0.723
2016 Huang J, Kang BH, Ishida E, Zhou T, Griesman T, Sheng Z, Wu F, Doria-Rose NA, Zhang B, McKee K, O'Dell S, Chuang GY, Druz A, Georgiev IS, Schramm CA, ... ... Kelsoe G, et al. Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth. Immunity. 45: 1108-1121. PMID 27851912 DOI: 10.1016/J.Immuni.2016.10.027  0.326
2016 Bradley T, Yang G, Ilkayeva O, Holl TM, Zhang R, Zhang J, Santra S, Fox CB, Reed SG, Parks R, Bowman CM, Bouton-Verville H, Sutherland LL, Scearce RM, Vandergrift N, ... ... Kelsoe G, et al. HIV-1 Envelope Mimicry of Host Enzyme Kynureninase Does Not Disrupt Tryptophan Metabolism. Journal of Immunology (Baltimore, Md. : 1950). PMID 27849170 DOI: 10.4049/Jimmunol.1601484  0.305
2016 van Gils MJ, van den Kerkhof TL, Ozorowski G, Cottrell CA, Sok D, Pauthner M, Pallesen J, de Val N, Yasmeen A, de Taeye SW, Schorcht A, Gumbs S, Johanna I, Saye-Francisco K, Liang CH, ... ... Kelsoe G, et al. An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability. Nature Microbiology. 2: 16199. PMID 27841852 DOI: 10.1038/Nmicrobiol.2016.199  0.351
2016 Su KY, Watanabe A, Yeh CH, Kelsoe G, Kuraoka M. Efficient Culture of Human Naive and Memory B Cells for Use as APCs. Journal of Immunology (Baltimore, Md. : 1950). 197: 4163-4176. PMID 27815447 DOI: 10.4049/Jimmunol.1502193  0.743
2016 Abbott RK, Thayer M, Labuda J, Silva M, Philbrook P, Cain DW, Kojima H, Hatfield S, Sethumadhavan S, Ohta A, Reinherz EL, Kelsoe G, Sitkovsky M. Germinal Center Hypoxia Potentiates Immunoglobulin Class Switch Recombination. Journal of Immunology (Baltimore, Md. : 1950). PMID 27798169 DOI: 10.4049/Jimmunol.1601401  0.724
2016 Khandelwal S, Lee GM, Hester CG, Poncz M, McKenzie S, Sachais BS, Rauova L, Kelsoe G, Cines DB, Frank M, Arepally GM. The antigenic complex in HIT binds to B-cells via complement and complement receptor 2 (CD21). Blood. PMID 27412887 DOI: 10.1182/Blood-2016-04-709634  0.467
2016 Zhang R, Verkoczy L, Wiehe K, Munir Alam S, Nicely NI, Santra S, Bradley T, Pemble CW, Zhang J, Gao F, Montefiori DC, Bouton-Verville H, Kelsoe G, Larimore K, Greenberg PD, et al. Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages. Science Translational Medicine. 8: 336ra62. PMID 27122615 DOI: 10.1126/Scitranslmed.Aaf0618  0.439
2016 Bonsignori M, Zhou T, Sheng Z, Chen L, Gao F, Joyce MG, Ozorowski G, Chuang GY, Schramm CA, Wiehe K, Alam SM, Bradley T, Gladden MA, Hwang KK, Iyengar S, ... ... Kelsoe G, et al. Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody. Cell. PMID 26949186 DOI: 10.1016/J.Cell.2016.02.022  0.339
2016 Kuraoka M, Schmidt AG, Nojima T, Feng F, Watanabe A, Kitamura D, Harrison SC, Kepler TB, Kelsoe G. Complex Antigens Drive Permissive Clonal Selection in Germinal Centers. Immunity. PMID 26948373 DOI: 10.1016/J.Immuni.2016.02.010  0.776
2016 Haynes BF, Shaw GM, Korber B, Kelsoe G, Sodroski J, Hahn BH, Borrow P, McMichael AJ. HIV-Host Interactions: Implications for Vaccine Design. Cell Host & Microbe. 19: 292-303. PMID 26922989 DOI: 10.1016/J.Chom.2016.02.002  0.35
2015 Bradley T, Fera D, Bhiman J, Eslamizar L, Lu X, Anasti K, Zhang R, Sutherland LL, Scearce RM, Bowman CM, Stolarchuk C, Lloyd KE, Parks R, Eaton A, Foulger A, ... ... Kelsoe G, et al. Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site. Cell Reports. PMID 26725118 DOI: 10.1016/J.Celrep.2015.12.017  0.4
2015 Ci X, Kuraoka M, Wang H, Carico Z, Hopper K, Shin J, Deng X, Qiu Y, Unniraman S, Kelsoe G, Zhong XP. TSC1 Promotes B Cell Maturation but Is Dispensable for Germinal Center Formation. Plos One. 10: e0127527. PMID 26000908 DOI: 10.1371/Journal.Pone.0127527  0.788
2015 Reynolds AE, Kuraoka M, Kelsoe G. Natural IgM is produced by CD5- plasma cells that occupy a distinct survival niche in bone marrow. Journal of Immunology (Baltimore, Md. : 1950). 194: 231-42. PMID 25429072 DOI: 10.4049/Jimmunol.1401203  0.741
2015 Liu M, Yang G, Wiehe K, Nicely NI, Vandergrift NA, Rountree W, Bonsignori M, Alam SM, Gao J, Haynes BF, Kelsoe G. Polyreactivity and autoreactivity among HIV-1 antibodies. Journal of Virology. 89: 784-98. PMID 25355869 DOI: 10.1128/Jvi.02378-14  0.355
2014 Wiehe K, Easterhoff D, Luo K, Nicely NI, Bradley T, Jaeger FH, Dennison SM, Zhang R, Lloyd KE, Stolarchuk C, Parks R, Sutherland LL, Scearce RM, Morris L, Kaewkungwal J, ... ... Kelsoe G, et al. Antibody light-chain-restricted recognition of the site of immune pressure in the RV144 HIV-1 vaccine trial is phylogenetically conserved. Immunity. 41: 909-18. PMID 25526306 DOI: 10.1016/J.Immuni.2014.11.014  0.361
2014 Kelsoe G. Curiouser and curiouser: the role(s) of AID expression in self-tolerance. European Journal of Immunology. 44: 2876-9. PMID 25308427 DOI: 10.1002/Eji.201445102  0.441
2014 Kepler TB, Liao HX, Alam SM, Bhaskarabhatla R, Zhang R, Yandava C, Stewart S, Anasti K, Kelsoe G, Parks R, Lloyd KE, Stolarchuk C, Pritchett J, Solomon E, Friberg E, et al. Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies. Cell Host & Microbe. 16: 304-13. PMID 25211073 DOI: 10.1016/J.Chom.2014.08.006  0.337
2014 Haynes BF, Moody MA, Alam M, Bonsignori M, Verkoczy L, Ferrari G, Gao F, Tomaras GD, Liao HX, Kelsoe G. Progress in HIV-1 vaccine development. The Journal of Allergy and Clinical Immunology. 134: 3-10; quiz 11. PMID 25117798 DOI: 10.1016/J.Jaci.2014.04.025  0.33
2014 Gao F, Bonsignori M, Liao HX, Kumar A, Xia SM, Lu X, Cai F, Hwang KK, Song H, Zhou T, Lynch RM, Alam SM, Moody MA, Ferrari G, Berrong M, ... Kelsoe G, et al. Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies. Cell. 158: 481-91. PMID 25065977 DOI: 10.1016/J.Cell.2014.06.022  0.49
2014 Kelsoe G, Verkoczy L, Haynes BF. Immune System Regulation in the Induction of Broadly Neutralizing HIV-1 Antibodies. Vaccines. 2: 1-14. PMID 24932410 DOI: 10.3390/Vaccines2010001  0.384
2014 Haynes BF, Verkoczy L, Kelsoe G. Redemption of autoreactive B cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 9022-3. PMID 24920593 DOI: 10.1073/Pnas.1407877111  0.523
2014 Verkoczy L, Kelsoe G, Haynes BF. HIV-1 envelope gp41 broadly neutralizing antibodies: hurdles for vaccine development. Plos Pathogens. 10: e1004073. PMID 24853821 DOI: 10.1371/Journal.Ppat.1004073  0.369
2014 Kepler TB, Munshaw S, Wiehe K, Zhang R, Yu JS, Woods CW, Denny TN, Tomaras GD, Alam SM, Moody MA, Kelsoe G, Liao HX, Haynes BF. Reconstructing a B-Cell Clonal Lineage. II. Mutation, Selection, and Affinity Maturation. Frontiers in Immunology. 5: 170. PMID 24795717 DOI: 10.3389/Fimmu.2014.00170  0.418
2014 Caro-Maldonado A, Wang R, Nichols AG, Kuraoka M, Milasta S, Sun LD, Gavin AL, Abel ED, Kelsoe G, Green DR, Rathmell JC. Metabolic reprogramming is required for antibody production that is suppressed in anergic but exaggerated in chronically BAFF-exposed B cells. Journal of Immunology (Baltimore, Md. : 1950). 192: 3626-36. PMID 24616478 DOI: 10.4049/Jimmunol.1302062  0.748
2014 Hwang KK, Trama AM, Kozink DM, Chen X, Wiehe K, Cooper AJ, Xia SM, Wang M, Marshall DJ, Whitesides J, Alam M, Tomaras GD, Allen SL, Rai KR, McKeating J, ... ... Kelsoe G, et al. IGHV1-69 B cell chronic lymphocytic leukemia antibodies cross-react with HIV-1 and hepatitis C virus antigens as well as intestinal commensal bacteria. Plos One. 9: e90725. PMID 24614505 DOI: 10.1371/Journal.Pone.0090725  0.492
2014 Bonsignori M, Wiehe K, Grimm SK, Lynch R, Yang G, Kozink DM, Perrin F, Cooper AJ, Hwang KK, Chen X, Liu M, McKee K, Parks RJ, Eudailey J, Wang M, ... ... Kelsoe G, et al. An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1. The Journal of Clinical Investigation. 124: 1835-43. PMID 24614107 DOI: 10.1172/Jci73441  0.367
2014 Holl TM, Yang G, Kuraoka M, Verkoczy L, Alam SM, Moody MA, Haynes BF, Kelsoe G. Enhanced antibody responses to an HIV-1 membrane-proximal external region antigen in mice reconstituted with cultured lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 192: 3269-79. PMID 24591365 DOI: 10.4049/Jimmunol.1302829  0.768
2014 Gearhart PJ, Kelsoe G. A tribute to Michael S. Neuberger. The Journal of Clinical Investigation. 124: 3-5. PMID 24382382 DOI: 10.1172/Jci74366  0.428
2013 Cain DW, O'Koren EG, Kan MJ, Womble M, Sempowski GD, Hopper K, Gunn MD, Kelsoe G. Identification of a tissue-specific, C/EBPβ-dependent pathway of differentiation for murine peritoneal macrophages. Journal of Immunology (Baltimore, Md. : 1950). 191: 4665-75. PMID 24078688 DOI: 10.4049/Jimmunol.1300581  0.657
2013 Kim M, Song L, Moon J, Sun ZY, Bershteyn A, Hanson M, Cain D, Goka S, Kelsoe G, Wagner G, Irvine D, Reinherz EL. Immunogenicity of membrane-bound HIV-1 gp41 membrane-proximal external region (MPER) segments is dominated by residue accessibility and modulated by stereochemistry. The Journal of Biological Chemistry. 288: 31888-901. PMID 24047898 DOI: 10.1074/Jbc.M113.494609  0.681
2013 McWilliams L, Su KY, Liang X, Liao D, Floyd S, Amos J, Moody MA, Kelsoe G, Kuraoka M. The human fetal lymphocyte lineage: identification by CD27 and LIN28B expression in B cell progenitors. Journal of Leukocyte Biology. 94: 991-1001. PMID 23901121 DOI: 10.1189/Jlb.0113048  0.741
2013 Liao HX, Lynch R, Zhou T, Gao F, Munir Alam S, Boyd SD, Fire AZ, Roskin KM, Schramm CA, Zhang Z, Zhu J, Shapiro L, Mullikin JC, Gnanakaran S, Hraber P, ... ... Kelsoe G, et al. Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus Nature. 496: 469-476. PMID 23552890 DOI: 10.1038/Nature12053  0.368
2013 Yang G, Holl TM, Liu Y, Li Y, Lu X, Nicely NI, Kepler TB, Alam SM, Liao HX, Cain DW, Spicer L, VandeBerg JL, Haynes BF, Kelsoe G. Identification of autoantigens recognized by the 2F5 and 4E10 broadly neutralizing HIV-1 antibodies. The Journal of Experimental Medicine. 210: 241-56. PMID 23359068 DOI: 10.1084/Jem.20121977  0.675
2013 Cain DW, Sanders SE, Cunningham MM, Kelsoe G. Disparate adjuvant properties among three formulations of "alum". Vaccine. 31: 653-60. PMID 23200935 DOI: 10.1016/J.Vaccine.2012.11.044  0.69
2013 Haynes BF, Kepler TB, Alam SM, Harrison S, Bonsignori M, Moody MA, Kelsoe G, Verkoczy L, Liao H. E108 Analysis of Broad Neutralizing B Cell Lineages to Guide HIV-1 Immunogen Design Jaids Journal of Acquired Immune Deficiency Syndromes. 62: S54. DOI: 10.1097/01.Qai.0000429246.24534.32  0.372
2012 Friedman J, Alam SM, Shen X, Xia SM, Stewart S, Anasti K, Pollara J, Fouda GG, Yang G, Kelsoe G, Ferrari G, Tomaras GD, Haynes BF, Liao HX, Moody MA, et al. Isolation of HIV-1-neutralizing mucosal monoclonal antibodies from human colostrum. Plos One. 7: e37648. PMID 22624058 DOI: 10.1371/Journal.Pone.0037648  0.375
2012 Haynes BF, Kelsoe G, Harrison SC, Kepler TB. B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study. Nature Biotechnology. 30: 423-33. PMID 22565972 DOI: 10.1038/Nbt.2197  0.385
2012 Moody MA, Yates NL, Amos JD, Drinker MS, Eudailey JA, Gurley TC, Marshall DJ, Whitesides JF, Chen X, Foulger A, Yu JS, Zhang R, Meyerhoff RR, Parks R, Scull JC, ... ... Kelsoe G, et al. HIV-1 gp120 vaccine induces affinity maturation in both new and persistent antibody clonal lineages. Journal of Virology. 86: 7496-507. PMID 22553329 DOI: 10.1128/Jvi.00426-12  0.425
2012 McWilliams L, Su K, Liang X, Floyd S, Amos J, Moody M, Kelsoe G, Kuraoka M. CD27+ Developing B Cells are Common in Human Fetal Liver Journal of Allergy and Clinical Immunology. 129: AB12. DOI: 10.1016/J.Jaci.2011.12.906  0.341
2011 Kuraoka M, Kelsoe G. A novel role for activation-induced cytidine deaminase: central B-cell tolerance. Cell Cycle (Georgetown, Tex.). 10: 3423-4. PMID 22067654 DOI: 10.4161/Cc.10.20.17693  0.78
2011 Moody MA, Zhang R, Walter EB, Woods CW, Ginsburg GS, McClain MT, Denny TN, Chen X, Munshaw S, Marshall DJ, Whitesides JF, Drinker MS, Amos JD, Gurley TC, Eudailey JA, ... ... Kelsoe G, et al. H3N2 influenza infection elicits more cross-reactive and less clonally expanded anti-hemagglutinin antibodies than influenza vaccination. Plos One. 6: e25797. PMID 22039424 DOI: 10.1371/Journal.Pone.0025797  0.356
2011 Liao HX, Chen X, Munshaw S, Zhang R, Marshall DJ, Vandergrift N, Whitesides JF, Lu X, Yu JS, Hwang KK, Gao F, Markowitz M, Heath SL, Bar KJ, Goepfert PA, ... ... Kelsoe G, et al. Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated Journal of Experimental Medicine. 208: 2237-2249. PMID 21987658 DOI: 10.1084/Jem.20110363  0.359
2011 Alam SM, Liao HX, Dennison SM, Jaeger F, Parks R, Anasti K, Foulger A, Donathan M, Lucas J, Verkoczy L, Nicely N, Tomaras GD, Kelsoe G, Chen B, Kepler TB, et al. Differential reactivity of germ line allelic variants of a broadly neutralizing HIV-1 antibody to a gp41 fusion intermediate conformation. Journal of Virology. 85: 11725-31. PMID 21917975 DOI: 10.1128/Jvi.05680-11  0.373
2011 Verkoczy L, Chen Y, Bouton-Verville H, Zhang J, Diaz M, Hutchinson J, Ouyang YB, Alam SM, Holl TM, Hwang KK, Kelsoe G, Haynes BF. Rescue of HIV-1 broad neutralizing antibody-expressing B cells in 2F5 VH x VL knockin mice reveals multiple tolerance controls. Journal of Immunology (Baltimore, Md. : 1950). 187: 3785-97. PMID 21908739 DOI: 10.4049/Jimmunol.1101633  0.423
2011 Bonsignori M, Hwang KK, Chen X, Tsao CY, Morris L, Gray E, Marshall DJ, Crump JA, Kapiga SH, Sam NE, Sinangil F, Pancera M, Yongping Y, Zhang B, Zhu J, ... ... Kelsoe G, et al. Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors. Journal of Virology. 85: 9998-10009. PMID 21795340 DOI: 10.1128/Jvi.05045-11  0.391
2011 Kuraoka M, Holl TM, Liao D, Womble M, Cain DW, Reynolds AE, Kelsoe G. Activation-induced cytidine deaminase mediates central tolerance in B cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 11560-5. PMID 21700885 DOI: 10.1073/Pnas.1102571108  0.831
2011 Cain DW, Snowden PB, Sempowski GD, Kelsoe G. Inflammation triggers emergency granulopoiesis through a density-dependent feedback mechanism. Plos One. 6: e19957. PMID 21655273 DOI: 10.1371/Journal.Pone.0019957  0.754
2011 Kelsoe G. B cell tolerance: putting the horse before the cart. Arthritis and Rheumatism. 63: 1173-6. PMID 21538309 DOI: 10.1002/Art.30162  0.506
2011 Verkoczy L, Kelsoe G, Moody MA, Haynes BF. Role of immune mechanisms in induction of HIV-1 broadly neutralizing antibodies. Current Opinion in Immunology. 23: 383-90. PMID 21524897 DOI: 10.1016/J.Coi.2011.04.003  0.35
2011 Holl EK, O'Connor BP, Holl TM, Roney KE, Zimmermann AG, Jha S, Kelsoe G, Ting JP. Plexin-D1 is a novel regulator of germinal centers and humoral immune responses. Journal of Immunology (Baltimore, Md. : 1950). 186: 5603-11. PMID 21464091 DOI: 10.4049/Jimmunol.1003464  0.478
2011 McGowan PO, Hope TA, Meck WH, Kelsoe G, Williams CL. Impaired social recognition memory in recombination activating gene 1-deficient mice. Brain Research. 1383: 187-95. PMID 21354115 DOI: 10.1016/J.Brainres.2011.02.054  0.312
2011 Kuraoka M, McWilliams L, Kelsoe G. AID expression during B-cell development: searching for answers. Immunologic Research. 49: 3-13. PMID 21136202 DOI: 10.1007/S12026-010-8185-7  0.767
2010 Kelsoe G, Cain D. A new guise for hyper-IgM syndrome. Blood. 116: 5785-6. PMID 21183692 DOI: 10.1182/Blood-2010-09-303404  0.617
2010 Nicely NI, Dennison SM, Spicer L, Scearce RM, Kelsoe G, Ueda Y, Chen H, Liao HX, Alam SM, Haynes BF. Crystal structure of a non-neutralizing antibody to the HIV-1 gp41 membrane-proximal external region. Nature Structural & Molecular Biology. 17: 1492-4. PMID 21076400 DOI: 10.1038/Nsmb.1944  0.304
2010 Chen H, Liao D, Holl TM, Snowden P, Ueda Y, Kelsoe G. Genetic regulation of pristane-induced oil granuloma responses. International Journal of Experimental Pathology. 91: 472-83. PMID 20804539 DOI: 10.1111/J.1365-2613.2010.00732.X  0.793
2010 Chen H, Liao D, Cain D, McLeod I, Ueda Y, Guan Z, Raetz C, Kelsoe G. Distinct granuloma responses in C57BL/6J and BALB/cByJ mice in response to pristane International Journal of Experimental Pathology. 91: 460-471. PMID 20681981 DOI: 10.1111/J.1365-2613.2010.00725.X  0.645
2010 Holl TM, Haynes BF, Kelsoe G. Stromal cell independent B cell development in vitro: generation and recovery of autoreactive clones. Journal of Immunological Methods. 354: 53-67. PMID 20109461 DOI: 10.1016/J.Jim.2010.01.007  0.502
2010 Verkoczy L, Diaz M, Holl TM, Ouyang YB, Bouton-Verville H, Alam SM, Liao HX, Kelsoe G, Haynes BF. Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance. Proceedings of the National Academy of Sciences of the United States of America. 107: 181-6. PMID 20018688 DOI: 10.1073/Pnas.0912914107  0.434
2009 Verkoczy L, Moody MA, Holl TM, Bouton-Verville H, Scearce RM, Hutchinson J, Alam SM, Kelsoe G, Haynes BF. Functional, non-clonal IgMa-restricted B cell receptor interactions with the HIV-1 envelope gp41 membrane proximal external region. Plos One. 4: e7215. PMID 19806186 DOI: 10.1371/Journal.Pone.0007215  0.459
2009 Kuraoka M, Liao D, Yang K, Allgood SD, Levesque MC, Kelsoe G, Ueda Y. Activation-induced cytidine deaminase expression and activity in the absence of germinal centers: insights into hyper-IgM syndrome. Journal of Immunology (Baltimore, Md. : 1950). 183: 3237-48. PMID 19667096 DOI: 10.4049/Jimmunol.0901548  0.799
2009 Bonsignori M, Moody MA, Parks RJ, Holl TM, Kelsoe G, Hicks CB, Vandergrift N, Tomaras GD, Haynes BF. HIV-1 envelope induces memory B cell responses that correlate with plasma antibody levels after envelope gp120 protein vaccination or HIV-1 infection. Journal of Immunology (Baltimore, Md. : 1950). 183: 2708-17. PMID 19625640 DOI: 10.4049/Jimmunol.0901068  0.379
2009 Levesque MC, Moody MA, Hwang KK, Marshall DJ, Whitesides JF, Amos JD, Gurley TC, Allgood S, Haynes BB, Vandergrift NA, Plonk S, Parker DC, Cohen MS, Tomaras GD, Goepfert PA, ... ... Kelsoe G, et al. Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection. Plos Medicine. 6: e1000107. PMID 19582166 DOI: 10.1371/Journal.Pmed.1000107  0.358
2009 Lieberman AE, Kuraoka M, Davila M, Kelsoe G, Cowell LG. Conserved cryptic recombination signals in Vkappa gene segments are cleaved in small pre-B cells. Bmc Immunology. 10: 37. PMID 19555491 DOI: 10.1186/1471-2172-10-37  0.781
2009 Ueda Y, Cain DW, Kuraoka M, Kondo M, Kelsoe G. IL-1R type I-dependent hemopoietic stem cell proliferation is necessary for inflammatory granulopoiesis and reactive neutrophilia. Journal of Immunology (Baltimore, Md. : 1950). 182: 6477-84. PMID 19414802 DOI: 10.4049/Jimmunol.0803961  0.776
2009 Cain D, Kondo M, Chen H, Kelsoe G. Effects of acute and chronic inflammation on B-cell development and differentiation. The Journal of Investigative Dermatology. 129: 266-77. PMID 19148216 DOI: 10.1038/Jid.2008.286  0.697
2009 Bonsignori M, Moody M, Parks R, Holl T, Kelsoe G, Hicks C, Vandergrift N, Tomaras G, Haynes B. P04-48. HIV-1 envelope induces memory B cell responses that correlate with plasma antibody levels after gp120 protein vaccination or chronic HIV-1 infection Retrovirology. 6: 76. DOI: 10.1186/1742-4690-6-S3-P76  0.39
2009 Liao L, Chen X, Dixon A, Munshaw S, Moody M, Zhang R, Nagel A, Foulger A, Derosa K, Parks R, Mcparland M, Whitesides J, Marshall D, Amos J, Yang Y, ... ... Kelsoe G, et al. P04-45. Characterization of the plasma cell repertoire in acute HIV-1 infection (AHI) Retrovirology. 6: 73. DOI: 10.1186/1742-4690-6-S3-P73  0.34
2009 Holl TM, Kuraoka M, Liao D, Verkoczy L, Moody MA, Alam M, Liao H, Haynes BF, Kelsoe GH. P04-44. Generation of antibody responses to HIV-1 membrane proximal external region (MPER) antigen Retrovirology. 6. DOI: 10.1186/1742-4690-6-S3-P72  0.336
2009 Verkoczy L, Diaz M, Holl TM, Ouyang Y, Bouton-Verville H, Alam SM, Liao H, Kelsoe G, Haynes BF. P04-26. Immunological tolerance prevents the expression of a broadly reactive neutralizing HIV-1 antibody Retrovirology. 6. DOI: 10.1186/1742-4690-6-S3-P54  0.376
2009 Cain D, Ueda Y, Holl T, Snowden P, Kondo M, Kelsoe G. T.20. Evidence for a Single Pathway of Neutrophil Production to Explain Both “Steady-state” and “Emergency” Granulopoiesis Clinical Immunology. 131: S56-S57. DOI: 10.1016/J.Clim.2009.03.161  0.74
2008 DiLillo DJ, Hamaguchi Y, Ueda Y, Yang K, Uchida J, Haas KM, Kelsoe G, Tedder TF. Maintenance of long-lived plasma cells and serological memory despite mature and memory B cell depletion during CD20 immunotherapy in mice. Journal of Immunology (Baltimore, Md. : 1950). 180: 361-71. PMID 18097037 DOI: 10.4049/Jimmunol.180.1.361  0.638
2007 Davila M, Liu F, Cowell LG, Lieberman AE, Heikamp E, Patel A, Kelsoe G. Multiple, conserved cryptic recombination signals in VH gene segments: detection of cleavage products only in pro B cells. The Journal of Experimental Medicine. 204: 3195-208. PMID 18056287 DOI: 10.1084/Jem.20071224  0.678
2007 Alam SM, McAdams M, Boren D, Rak M, Scearce RM, Gao F, Camacho ZT, Gewirth D, Kelsoe G, Chen P, Haynes BF. The role of antibody polyspecificity and lipid reactivity in binding of broadly neutralizing anti-HIV-1 envelope human monoclonal antibodies 2F5 and 4E10 to glycoprotein 41 membrane proximal envelope epitopes. Journal of Immunology (Baltimore, Md. : 1950). 178: 4424-35. PMID 17372000 DOI: 10.4049/Jimmunol.178.7.4424  0.305
2007 Ueda Y, Liao D, Yang K, Patel A, Kelsoe G. T-independent activation-induced cytidine deaminase expression, class-switch recombination, and antibody production by immature/transitional 1 B cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 3593-601. PMID 17339456 DOI: 10.4049/Jimmunol.178.6.3593  0.667
2007 Volkheimer AD, Weinberg JB, Beasley BE, Whitesides JF, Gockerman JP, Moore JO, Kelsoe G, Goodman BK, Levesque MC. Progressive immunoglobulin gene mutations in chronic lymphocytic leukemia: evidence for antigen-driven intraclonal diversification. Blood. 109: 1559-67. PMID 17082314 DOI: 10.1182/Blood-2006-05-020644  0.431
2006 Murray JM, O'Neill JP, Messier T, Rivers J, Walker VE, McGonagle B, Trombley L, Cowell LG, Kelsoe G, McBlane F, Finette BA. V(D)J recombinase-mediated processing of coding junctions at cryptic recombination signal sequences in peripheral T cells during human development. Journal of Immunology (Baltimore, Md. : 1950). 177: 5393-404. PMID 17015725 DOI: 10.4049/Jimmunol.177.8.5393  0.324
2006 Holl TM, Kelsoe G. Outside influence: TLRs direct hematopoietic cell fates. Immunity. 24: 667-9. PMID 16782021 DOI: 10.1016/J.Immuni.2006.06.007  0.353
2005 Haynes BF, Moody MA, Verkoczy L, Kelsoe G, Alam SM. Antibody polyspecificity and neutralization of HIV-1: a hypothesis. Human Antibodies. 14: 59-67. PMID 16720975 DOI: 10.3233/Hab-2005-143-402  0.382
2005 Ueda Y, Kondo M, Kelsoe G. Inflammation and the reciprocal production of granulocytes and lymphocytes in bone marrow. The Journal of Experimental Medicine. 201: 1771-80. PMID 15939792 DOI: 10.1084/Jem.20041419  0.305
2004 Cowell LG, Davila M, Ramsden D, Kelsoe G. Computational tools for understanding sequence variability in recombination signals. Immunological Reviews. 200: 57-69. PMID 15242396 DOI: 10.1111/J.0105-2896.2004.00171.X  0.583
2004 Gunn MD, Kelsoe G. Should we B-leavin' now? Nature Immunology. 5: 703-4. PMID 15224099 DOI: 10.1038/Ni0704-703  0.358
2004 Ueda Y, Yang K, Foster SJ, Kondo M, Kelsoe G. Inflammation controls B lymphopoiesis by regulating chemokine CXCL12 expression. The Journal of Experimental Medicine. 199: 47-58. PMID 14707114 DOI: 10.1084/Jem.20031104  0.563
2004 Kincade PW, Kelsoe G. Erratum: Corrigendum: A birthday for B cells: Lymphopoiesis II, a scientific symposium honoring Max Cooper Nature Immunology. 5: 554-554. DOI: 10.1038/Ni0504-554  0.384
2003 Sharov AA, Piao Y, Matoba R, Dudekula DB, Qian Y, VanBuren V, Falco G, Martin PR, Stagg CA, Bassey UC, Wang Y, Carter MG, Hamatani T, Aiba K, Akutsu H, ... ... Kelsoe G, et al. Transcriptome analysis of mouse stem cells and early embryos. Plos Biology. 1: E74. PMID 14691545 DOI: 10.1371/Journal.Pbio.0000074  0.322
2003 Kincade PW, Kelsoe G. A birthday for B cells: Lymphopoiesis II, a scientific symposium honoring Max Cooper. Nature Immunology. 4: 1155-7. PMID 14639461 DOI: 10.1038/Ni1203-1155  0.376
2003 Kelsoe G. Therapeutic CD154 antibody for lupus: promise for the future? The Journal of Clinical Investigation. 112: 1480-2. PMID 14617748 DOI: 10.1172/Jci20371  0.324
2003 Lee AI, Fugmann SD, Cowell LG, Ptaszek LM, Kelsoe G, Schatz DG. A functional analysis of the spacer of V(D)J recombination signal sequences. Plos Biology. 1: E1. PMID 14551903 DOI: 10.1371/Journal.Pbio.0000001  0.31
2003 Han S, Yang K, Ozen Z, Peng W, Marinova E, Kelsoe G, Zheng B. Enhanced differentiation of splenic plasma cells but diminished long-lived high-affinity bone marrow plasma cells in aged mice. Journal of Immunology (Baltimore, Md. : 1950). 170: 1267-73. PMID 12538685 DOI: 10.4049/Jimmunol.170.3.1267  0.587
2003 Cowell LG, Davila M, Yang K, Kepler TB, Kelsoe G. Prospective estimation of recombination signal efficiency and identification of functional cryptic signals in the genome by statistical modeling. The Journal of Experimental Medicine. 197: 207-20. PMID 12538660 DOI: 10.1084/Jem.20020250  0.638
2002 Cowell LG, Davila M, Kepler TB, Kelsoe G. Identification and utilization of arbitrary correlations in models of recombination signal sequences. Genome Biology. 3: RESEARCH0072. PMID 12537561 DOI: 10.1186/Gb-2002-3-12-Research0072  0.53
2002 Liang HE, Hsu LY, Cado D, Cowell LG, Kelsoe G, Schlissel MS. The "dispensable" portion of RAG2 is necessary for efficient V-to-DJ rearrangement during B and T cell development. Immunity. 17: 639-51. PMID 12433370 DOI: 10.1016/S1074-7613(02)00448-X  0.402
2002 Dal Porto JM, Haberman AM, Kelsoe G, Shlomchik MJ. Very low affinity B cells form germinal centers, become memory B cells, and participate in secondary immune responses when higher affinity competition is reduced. The Journal of Experimental Medicine. 195: 1215-21. PMID 11994427 DOI: 10.1084/Jem.20011550  0.522
2001 Luzina IG, Atamas SP, Storrer CE, DaSilva LC, Kelsoe G, Papadimitriou JC, Handwerger BS. Spontaneous formation of germinal centers in autoimmune mice Journal of Leukocyte Biology. 70: 578-584. PMID 11590194 DOI: 10.1189/Jlb.70.4.578  0.421
2001 Davila M, Foster S, Kelsoe G, Yang K. A role for secondary V(D)J recombination in oncogenic chromosomal translocations? Advances in Cancer Research. 81: 61-92. PMID 11430596 DOI: 10.1016/S0065-230X(01)81002-2  0.715
2001 Sandel PC, Gendelman M, Kelsoe G, Monroe JG. Definition of a novel cellular constituent of the bone marrow that regulates the response of immature B cells to B cell antigen receptor engagement Journal of Immunology. 166: 5935-5944. PMID 11342608 DOI: 10.4049/Jimmunol.166.10.5935  0.464
2001 Cerasoli DM, Kelsoe G, Sarzotti M. CD4+Thy1- thymocytes with a Th-type 2 cytokine response. International Immunology. 13: 75-83. PMID 11133836 DOI: 10.1093/Intimm/13.1.75  0.327
2000 Kelsoe G. Studies of the humoral immune response Immunologic Research. 22: 199-210. PMID 11339356 DOI: 10.1385/Ir:22:2-3:199  0.329
2000 Chen Z, Koralov SB, Kelsoe G. Complement C4 inhibits systemic autoimmunity through a mechanism independent of complement receptors CR1 and CR2. The Journal of Experimental Medicine. 192: 1339-52. PMID 11067882 DOI: 10.1084/Jem.192.9.1339  0.513
2000 Kelsoe G. Remembrance of things past Nature Immunology. 1: 375-376. PMID 11062494 DOI: 10.1038/80811  0.349
2000 Chen Z, Koralov SB, Kelsoe G. Regulation of humoral immune responses by CD21/CD35. Immunological Reviews. 176: 194-204. PMID 11043778 DOI: 10.1034/J.1600-065X.2000.00603.X  0.515
2000 Chen Z, Koralov SB, Gendelman M, Carroll MC, Kelsoe G. Humoral immune responses in Cr2-/- mice: enhanced affinity maturation but impaired antibody persistence. Journal of Immunology (Baltimore, Md. : 1950). 164: 4522-32. PMID 10779753 DOI: 10.4049/Jimmunol.164.9.4522  0.534
1999 Monroe RJ, Seidl KJ, Gaertner F, Han S, Chen F, Sekiguchi J, Wang J, Ferrini R, Davidson L, Kelsoe G, Alt FW. RAG2:GFP knockin mice reveal novel aspects of RAG2 expression in primary and peripheral lymphoid tissues. Immunity. 11: 201-12. PMID 10485655 DOI: 10.1016/S1074-7613(00)80095-3  0.473
1999 Takahashi Y, Cerasoli DM, Dal Porto JM, Shimoda M, Freund R, Fang W, Telander DG, Malvey EN, Mueller DL, Behrens TW, Kelsoe G. Relaxed negative selection in germinal centers and impaired affinity maturation in bcl-xL transgenic mice. The Journal of Experimental Medicine. 190: 399-410. PMID 10430628 DOI: 10.1084/Jem.190.3.399  0.444
1999 Yang K, Davila M, Kelsoe G. Do germinal centers have a role in the generation of lymphomas? Current Topics in Microbiology and Immunology. 246: 53-60; discussion 61. PMID 10396039 DOI: 10.1007/978-3-642-60162-0_7  0.643
1999 Kelsoe G. V(D)J hypermutation and receptor revision: Coloring outside the lines Current Opinion in Immunology. 11: 70-75. PMID 10047542 DOI: 10.1016/S0952-7915(99)80013-2  0.457
1998 Dal Porto JM, Haberman AM, Shlomchik MJ, Kelsoe G. Antigen drives very low affinity B cells to become plasmacytes and enter germinal centers Journal of Immunology. 161: 5373-5381. PMID 9820511  0.341
1998 Radmacher MD, Kelsoe G, Kepler TB. Predicted and inferred waiting times for key mutations in the germinal centre reaction: Evidence for stochasticity in selection Immunology and Cell Biology. 76: 373-381. PMID 9723780 DOI: 10.1046/J.1440-1711.1998.00753.X  0.369
1998 Kelsoe G. V(D)J hypermutation and DNA mismatch repair: Vexed by fixation Proceedings of the National Academy of Sciences of the United States of America. 95: 6576-6577. PMID 9618453 DOI: 10.1073/Pnas.95.12.6576  0.508
1998 Fischer MB, Goerg S, Shen L, Prodeus AP, Goodnow CC, Kelsoe G, Carroll MC. Dependence of germinal center B cells on expression of CD21/CD35 for survival Science. 280: 582-585. PMID 9554848 DOI: 10.1126/Science.280.5363.582  0.444
1998 Takahashi Y, Dutta PR, Cerasoli DM, Kelsoe G. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. V. Affinity maturation develops in two stages of clonal selection. The Journal of Experimental Medicine. 187: 885-95. PMID 9500791 DOI: 10.1084/Jem.187.6.885  0.389
1998 Kelsoe G, Flajnik MF. Somatic diversification of immune responses. Current Topics in Microbiology and Immunology. 0-221. DOI: 10.1007/978-3-642-71984-4  0.427
1997 Przylepa J, Himes C, Kelsoe G. Lymphocyte development and selection in germinal centers Current Topics in Microbiology and Immunology. 229: 85-104. PMID 9479850 DOI: 10.1007/978-3-642-71984-4_8  0.344
1997 Han S, Dillon SR, Zheng B, Shimoda M, Schlissel MS, Kelsoe G. V(D)J recombinase activity in a subset of germinal center B lymphocytes. Science (New York, N.Y.). 278: 301-5. PMID 9323211 DOI: 10.1126/Science.278.5336.301  0.463
1997 Han S, Zheng B, Takahashi Y, Kelsoe G. Distinctive characteristics of germinal center B cells Seminars in Immunology. 9: 255-260. PMID 9237932 DOI: 10.1006/Smim.1997.0081  0.472
1996 Zheng B, Han S, Kelsoe G. T helper cells in murine germinal centers are antigen-specific emigrants that downregulate Thy-1 Journal of Experimental Medicine. 184: 1083-1091. PMID 9064325 DOI: 10.1084/Jem.184.3.1083  0.412
1996 Han S, Zheng B, Schatz DG, Spanopoulou E, Kelsoe G. Neoteny in lymphocytes: Rag1 and Rag2 expression in germinal center B cells. Science (New York, N.Y.). 274: 2094-7. PMID 8953043 DOI: 10.1126/Science.274.5295.2094  0.476
1996 Pao W, Wen L, Smith AL, Gulbranson-Judge A, Zheng B, Kelsoe G, MacLennan ICM, Owen MJ, Hayday AC. γδ T cell help of B cells is induced by repeated parasitic infection, in the absence of other T cells Current Biology. 6: 1317-1325. PMID 8939571 DOI: 10.1016/S0960-9822(02)70718-5  0.461
1996 Zheng B, Kelsoe G, Han S. Somatic diversification of antibody responses Journal of Clinical Immunology. 16: 1-11. PMID 8926280 DOI: 10.1007/Bf01540967  0.411
1996 Zheng B, Han S, Zhu Q, Goldsby R, Kelsoe G. Alternative pathways for the selection of antigen-specific peripheral T cells Nature. 384: 263-266. PMID 8918876 DOI: 10.1038/384263A0  0.413
1996 Fischer MB, Ma M, Goerg S, Zhou X, Xia J, Finco O, Han S, Kelsoe G, Howard RG, Rothstein TL, Kremmer E, Rosen FS, Carroll MC. Regulation of the B cell response to T-dependent antigens by classical pathway complement Journal of Immunology. 157: 549-556. PMID 8752901  0.301
1996 Kelsoe G. The germinal center: A crucible for lymphocyte selection Seminars in Immunology. 8: 179-184. PMID 8738917 DOI: 10.1006/Smim.1996.0022  0.439
1996 Croix DA, Ahearn JM, Rosengard AM, Han S, Kelsoe G, Ma M, Carroll MC. Antibody response to a T-dependent antigen requires B cell expression of complement receptors Journal of Experimental Medicine. 183: 1857-1864. PMID 8666942 DOI: 10.1084/Jem.183.4.1857  0.492
1996 Ferguson SE, Han S, Kelsoe G, Thompson CB. CD28 is required for germinal center formation Journal of Immunology. 156: 4576-4581. PMID 8648099  0.375
1996 Wen L, Pao W, Wong FS, Peng Q, Craft J, Zheng B, Kelsoe G, Dianda L, Owen MJ, Hayday AC. Germinal center formation, immunoglobulin class switching, and autoantibody production driven by "non α/β" T cells Journal of Experimental Medicine. 183: 2271-2282. PMID 8642336 DOI: 10.1084/Jem.183.5.2271  0.366
1995 Saitoh Y, Kelsoe G, Bona C, Kaushik A. Skewed vh and vk gene family expression and pairing occurs among b lymphocytes in autoimmune motheaten mice Autoimmunity. 21: 185-193. PMID 8822276 DOI: 10.3109/08916939509008015  0.424
1995 Kelsoe G. In situ studies of the germinal center reaction Advances in Immunology. 60: 267-288. PMID 8607371 DOI: 10.1016/S0065-2776(08)60587-8  0.428
1995 Kaushik A, Kelsoe G, Jaton JC. The nude mutation results in impaired primary antibody repertoire European Journal of Immunology. 25: 631-634. PMID 7875225 DOI: 10.1002/Eji.1830250249  0.385
1995 Miller C, Kelsoe G. Ig VH hypermutation is absent in the germinal centers of aged mice Journal of Immunology. 155: 3377-3384. PMID 7561032  0.327
1995 Han S, Hathcock K, Zheng B, Kepler TB, Hodes R, Kelsoe G. Cellular interaction in germinal centers: Roles of CD40 ligand and B7-2 in established germinal centers Journal of Immunology. 155: 556-567. PMID 7541819  0.363
1995 Miller C, Stedra J, Kelsoe G, Cerny J. Facultative role of germinal centers and T cells in the somatic diversification of IgVH genes Journal of Experimental Medicine. 181: 1319-1331. PMID 7535332 DOI: 10.1084/Jem.181.4.1319  0.65
1995 Han S, Zheng B, Dal Porto J, Kelsoe G. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl IV. Affinity-dependent, antigen-driven B cell apoptosis in germinal centers as a mechanism for maintaining self-tolerance Journal of Experimental Medicine. 182: 1635-1644. PMID 7500008 DOI: 10.1084/Jem.182.6.1635  0.496
1995 Kelsoe G, Zheng B, Kepler TB. Hypermutation in T cells questioned Nature. 375: 286-286. DOI: 10.1038/375286A0  0.329
1994 Kelsoe G. B cell diversification and differentiation in the periphery Journal of Experimental Medicine. 180: 5-6. PMID 8006600 DOI: 10.1084/Jem.180.1.5  0.5
1994 Zheng B, Xue W, Kelsoe G. Locus-specific somatic hypermutation in germinal centre T cells Nature. 372: 556-559. PMID 7990929 DOI: 10.1038/372556A0  0.396
1994 Miller C, Kelsoe G, Han S. Lack of B7-2 expression in the germinal centers of aged mice Aging: Immunology and Infectious Disease. 5: 249-257.  0.326
1993 Jacob J, Przylepa J, Miller C, Kelsoe G. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. III. The kinetics of V region mutation and selection in germinal center B cells Journal of Experimental Medicine. 178: 1293-1307. PMID 8376935 DOI: 10.1084/Jem.178.4.1293  0.41
1993 Kelsoe G, Zheng B. Sites of B-cell activation in vivo Current Opinion in Immunology. 5: 418-422. PMID 8347301 DOI: 10.1016/0952-7915(93)90062-W  0.481
1993 Yurovsky VV, Kelsoe G. Pairing of VH gene families with the λ1 light chain: Evidence for a non-stochastic association European Journal of Immunology. 23: 1975-1979. PMID 8344362 DOI: 10.1002/Eji.1830230837  0.331
1992 Jacob J, Kelsoe G. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. II. A common clonal origin for periarteriolar lymphoid sheath-associated foci and germinal centers Journal of Experimental Medicine. 176: 679-687. PMID 1512536 DOI: 10.1084/Jem.176.3.679  0.675
1992 Jacob J, Miller C, Kelsoe G. In situ studies of the antigen-driven somatic hypermutation of immunoglobulin genes Immunology and Cell Biology. 70: 145-152. PMID 1398774 DOI: 10.1038/Icb.1992.19  0.331
1991 Jacob J, Kelsoe G, Rajewsky K, Weiss U. Intraclonal generation of antibody mutants in germinal centres Nature. 354: 389-392. PMID 1956400 DOI: 10.1038/354389A0  0.72
1991 Kelsoe G. The primary antibody repertoire: the somatic genotype and paratopic phenotype of B-cell populations Immunology Series. 55: 81-92. PMID 1954293  0.32
1991 Jacob J, Kassir R, Kelsoe G. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations Journal of Experimental Medicine. 173: 1165-1175. PMID 1902502 DOI: 10.1084/Jem.173.5.1165  0.453
1991 Kaushik A, Reininger L, Kelsoe G, Jaton JC, Bona C. Contribution of the VH11 gene family to mitogen-responsive B cell repertoire in C57BL/6 mice European Journal of Immunology. 21: 827-830. PMID 1901267  0.346
1991 Sarzotti M, Kumar V, Bennett M, Kelsoe G. Cloning of murine splenic T lymphocytes and natural killer (NK) cells on filter paper discs: Detection of a novel NK/T phenotype European Journal of Immunology. 21: 635-641. DOI: 10.1002/Eji.1830210315  0.36
1990 Kaushik A, Schulze DH, Bonilla FA, Bona C, Kelsoe G. Stochastic pairing of heavy-chain and kappa light-chain variable gene families occurs in polyclonally activated B cells. Proceedings of the National Academy of Sciences of the United States of America. 87: 4932-6. PMID 2114644 DOI: 10.1073/Pnas.87.13.4932  0.387
1989 Kelsoe G, Miceli R, Cerny J, Schulze DH. Mapping of antibody specificities to VH gene families Immunogenetics. 29: 288-296. PMID 2785504 DOI: 10.1007/Bf00352838  0.588
1989 Kaushik A, Schulze DH, Bona C, Kelsoe G. Murine V(κ) gene expression does not follow the V(H) paradigm Journal of Experimental Medicine. 169: 1859-1864. PMID 2497227 DOI: 10.1084/Jem.169.5.1859  0.325
1987 Kelsoe G. Cloning of mitogen- and antigen-reactive B lymphocytes on filter paper disks: Phenotypic and genotypic analysis of B cell colonies Methods in Enzymology. 150: 287-304. PMID 3501519 DOI: 10.1016/0076-6879(87)50086-6  0.452
1987 Schulze DH, Kelsoe G. Genotypic analysis of B cell colonies by in situ hybridization. Stoichiometric expression of three V(H) families in adult C57BL/6 and BALB/c mice Journal of Experimental Medicine. 166: 163-172. PMID 3110348 DOI: 10.1084/Jem.166.1.163  0.363
1986 Kelsoe G, Stout JT. Cloning of mitogen- and antigen-reactive B lymphocytes on filter paper discs. II. Paratope frequencies within the mitogen-selected repertoire Cellular Immunology. 98: 506-516. PMID 3530507 DOI: 10.1016/0008-8749(86)90309-6  0.397
1986 Kelsoe G. Regulation of the immune response. II. Concomitant idiotope-specific enhancement and suppression can result in a phenotypically normal response Cellular Immunology. 98: 145-155. PMID 2943430 DOI: 10.1016/0008-8749(86)90275-3  0.417
1985 Kelsoe G. Cloning of mitogen- and antigen-reactive B lymphocytes on filter paper discs. I. A description of the technique and of methods for the analysis of colonies Journal of Immunological Methods. 76: 345-363. PMID 2579160 DOI: 10.1016/0022-1759(85)90312-6  0.451
1985 Stout JT, Kelsoe GH, Cerny J. Clonal analysis of mitogen- and antigen-activated phosphorylcholine (PC specific B cells) Federation Proceedings. 44.  0.337
1984 Beyreuther K, Bovens J, Brüggemann M, Dildrop R, Kelsoe G, Krawinkel U, Müller C, Nishikawa S, Radbruch A, Reth M. Idiotypic determinants used in the analysis of antibody diversification and as regulatory targets. Annals of the New York Academy of Sciences. 418: 121-9. PMID 6201100 DOI: 10.1111/J.1749-6632.1983.Tb18060.X  0.309
1984 Cerny J, Kelsoe G. Priority of the anti-idiotypic response after antigen administration: artefact or intriguing network mechanism? Immunology Today. 5: 61-63. DOI: 10.1016/0167-5699(84)90165-8  0.598
1981 Kelsoe G, Reth M, Rajewsky K. Control of idiotype expression by monoclonal anti-idiotope and idiotope-bearing antibody European Journal of Immunology. 11: 418-423. PMID 6790289 DOI: 10.1002/Eji.1830110513  0.551
1981 Reth M, Kelsoe G, Rajewsky K. Idiotypic regulation by isologous monoclonal anti-idiotope antibodies Nature. 290: 257-259. PMID 6782489 DOI: 10.1038/290257A0  0.529
1980 Kelsoe G, Isaak D, Cerny J. Thymic requirement for cyclical idiotypic and reciprocal anti-idiotypic immune responses to a T-independent antigen Journal of Experimental Medicine. 151: 289-300. PMID 6965397 DOI: 10.1084/Jem.151.2.289  0.621
1980 Kelsoe G, Reth M, Rajewsky K. Control idiotope expression by monoclonal anti-idiotope antibodies Immunological Reviews. 52: 75-88. PMID 6790422 DOI: 10.1111/J.1600-065X.1980.Tb00331.X  0.489
1979 Kelsoe G, Cerny J. Reciprocal expansions of idiotypic and anti-idiotypic clones following antigen stimulation [17] Nature. 279: 333-334. PMID 313014 DOI: 10.1038/279333A0  0.614
1978 Kelsoe GH, Weller TH. Immunodiagnosis of infection with Schistosoma mansoni: Enzyme-linked immunosorbent assay for detection of antibody to circulating antigen Proceedings of the National Academy of Sciences of the United States of America. 75: 5715-5717. PMID 364488  0.512
1978 Kelsoe G, Cerny J. Regulation of the immune response. I. Regulatory cell equilibrium in the 'virgin' state European Journal of Immunology. 8: 176-180. PMID 77784 DOI: 10.1002/Eji.1830080307  0.414
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