Lao H. Saal, Ph.D. - Publications

Affiliations: 
2007 Columbia University, New York, NY 
Area:
Molecular Biology, Genetics, Bioinformatics Biology

84 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Meng P, Dalal H, Chen Y, Brueffer C, Gladchuk S, Alcaide M, Ehinger A, Saal LH. Digital PCR quantification of ultrahigh ERBB2 copy number identifies poor breast cancer survival after trastuzumab. Npj Breast Cancer. 10: 14. PMID 38374091 DOI: 10.1038/s41523-024-00621-x  0.327
2023 Dobilas A, Chen Y, Brueffer C, Leandersson P, Saal LH, Borgfeldt C. Preoperative ctDNA Levels Are Associated With Poor Overall Survival in Patients With Ovarian Cancer. Cancer Genomics & Proteomics. 20: 763-770. PMID 38035709 DOI: 10.21873/cgp.20423  0.341
2023 Li Y, Sundquist K, Vats S, Hong MG, Wang X, Chen Y, Hedelius A, Saal LH, Sundquist J, Memon AA. Mitochondrial heteroplasmic shifts reveal a positive selection of breast cancer. Journal of Translational Medicine. 21: 696. PMID 37798736 DOI: 10.1186/s12967-023-04534-4  0.373
2023 Demircan K, Bengtsson Y, Chillon TS, Vallon-Christersson J, Sun Q, Larsson C, Malmberg M, Saal LH, Rydén L, Borg Å, Manjer J, Schomburg L. Matched analysis of circulating selenium with the breast cancer selenotranscriptome: a multicentre prospective study. Journal of Translational Medicine. 21: 658. PMID 37741974 DOI: 10.1186/s12967-023-04502-y  0.404
2023 Dahlgren M, Lettiero B, Dalal H, Mårtensson K, Gaber A, Nodin B, Gruvberger-Saal SK, Saal LH, Howlin J. CITED1 as a marker of favourable outcome in anti-endocrine treated, estrogen-receptor positive, lymph-node negative breast cancer. Bmc Research Notes. 16: 105. PMID 37322548 DOI: 10.1186/s13104-023-06376-1  0.377
2023 Bengtsson Y, Demircan K, Vallon-Christersson J, Malmberg M, Saal LH, Rydén L, Borg Å, Schomburg L, Sandsveden M, Manjer J. Serum copper, zinc and copper/zinc ratio in relation to survival after breast cancer diagnosis: A prospective multicenter cohort study. Redox Biology. 63: 102728. PMID 37210781 DOI: 10.1016/j.redox.2023.102728  0.301
2022 Saghir H, Veerla S, Malmberg M, Rydén L, Ehinger A, Saal LH, Vallon-Christersson J, Borg Å, Hegardt C, Larsson C, Haidar A, Hedenfalk I, Loman N, Kimbung S. How Reliable Are Gene Expression-Based and Immunohistochemical Biomarkers Assessed on a Core-Needle Biopsy? A Study of Paired Core-Needle Biopsies and Surgical Specimens in Early Breast Cancer. Cancers. 14. PMID 36010992 DOI: 10.3390/cancers14164000  0.309
2022 Demircan K, Sun Q, Bengtsson Y, Seemann P, Vallon-Christersson J, Malmberg M, Saal LH, Rydén L, Minich WB, Borg Å, Manjer J, Schomburg L. Autoimmunity to selenoprotein P predicts breast cancer recurrence. Redox Biology. 53: 102346. PMID 35636018 DOI: 10.1016/j.redox.2022.102346  0.409
2022 Dalal H, Dahlgren M, Gladchuk S, Brueffer C, Gruvberger-Saal SK, Saal LH. Clinical associations of ESR2 (estrogen receptor beta) expression across thousands of primary breast tumors. Scientific Reports. 12: 4696. PMID 35304506 DOI: 10.1038/s41598-022-08210-3  0.491
2021 Demircan K, Bengtsson Y, Sun Q, Brange A, Vallon-Christersson J, Rijntjes E, Malmberg M, Saal LH, Rydén L, Borg Å, Manjer J, Schomburg L. Serum selenium, selenoprotein P and glutathione peroxidase 3 as predictors of mortality and recurrence following breast cancer diagnosis: A multicentre cohort study. Redox Biology. 47: 102145. PMID 34563873 DOI: 10.1016/j.redox.2021.102145  0.379
2021 Dahlgren M, George AM, Brueffer C, Gladchuk S, Chen Y, Vallon-Christersson J, Hegardt C, Häkkinen J, Rydén L, Malmberg M, Larsson C, Gruvberger-Saal SK, Ehinger A, Loman N, Borg Å, ... Saal LH, et al. Preexisting Somatic Mutations of Estrogen Receptor Alpha () in Early-Stage Primary Breast Cancer. Jnci Cancer Spectrum. 5: pkab028. PMID 33937624 DOI: 10.1093/jncics/pkab028  0.406
2020 Brueffer C, Gladchuk S, Winter C, Vallon-Christersson J, Hegardt C, Häkkinen J, George AM, Chen Y, Ehinger A, Larsson C, Loman N, Malmberg M, Rydén L, Borg Å, Saal LH. The mutational landscape of the SCAN-B real-world primary breast cancer transcriptome. Embo Molecular Medicine. e12118. PMID 32926574 DOI: 10.15252/Emmm.202012118  0.545
2020 Nilsson H, Lindgren D, Axelson H, Brueffer C, Saal LH, Lundgren J, Johansson ME. Features of increased malignancy in eosinophilic clear cell renal cell carcinoma. The Journal of Pathology. PMID 32815150 DOI: 10.1002/Path.5532  0.349
2020 Glodzik D, Bosch A, Hartman J, Aine M, Vallon-Christersson J, Reuterswärd C, Karlsson A, Mitra S, Niméus E, Holm K, Häkkinen J, Hegardt C, Saal LH, Larsson C, Malmberg M, et al. Comprehensive molecular comparison of BRCA1 hypermethylated and BRCA1 mutated triple negative breast cancers. Nature Communications. 11: 3747. PMID 32719340 DOI: 10.1038/S41467-020-17537-2  0.545
2020 Larsson C, Ehinger A, Winslow S, Leandersson K, Klintman M, Dahl L, Vallon-Christersson J, Häkkinen J, Hegardt C, Manjer J, Saal L, Rydén L, Malmberg M, Borg Å, Loman N. Prognostic implications of the expression levels of different immunoglobulin heavy chain-encoding RNAs in early breast cancer. Npj Breast Cancer. 6: 28. PMID 32656317 DOI: 10.1038/s41523-020-0170-2  0.37
2020 Pettersson L, Chen Y, George AM, Rigo R, Lazarevic V, Juliusson G, Saal LH, Ehinger M. Subclonal patterns in follow-up of acute myeloid leukemia combining whole exome sequencing and ultrasensitive IBSAFE digital droplet analysis. Leukemia & Lymphoma. 1-12. PMID 32425124 DOI: 10.1080/10428194.2020.1755855  0.317
2020 Staaf J, Glodzik D, Campos AB, Vallon-Christersson J, Reuterswärd C, Häkkinen J, Degasperi A, Amarante TD, Saal L, Hegardt C, Stobart H, Ehinger A, Larsson C, Ryden L, Loman N, et al. Whole-genome sequencing of triple negative breast cancers in a standard population-based clinical setting Breast Cancer Research and Treatment. 180: 531-532. PMID 32026211 DOI: 10.1007/S10549-019-05514-3  0.439
2020 Brueffer C, Gladchuk S, Winter C, Vallon-Christersson J, Hegardt C, Häkkinen J, George AM, Chen Y, Ehinger A, Larsson C, Loman N, Malmberg M, Rydén L, Borg Å, Saal LH. Defining the mutational landscape of 3,217 primary breast cancer transcriptomes through large-scale RNA-seq within the Sweden Cancerome Analysis Network: Breast Project (SCAN-B; NCT03430492). Journal of Clinical Oncology. 38: 518-518. DOI: 10.1200/Jco.2020.38.15_Suppl.518  0.547
2020 Malmberg M, Larsson C, Vallon-Christersson J, Ehinger A, Hegardt C, Killander F, Ryden L, Saal LH, Loman N, Borg Å. Abstract P1-18-10: Preoperative treatment of HER2-positive breast cancer in South Sweden. A retrospective, comprehensive survey of neo-adjuvant treated HER2-positve breast cancer in the SCAN-B project 2010-2017 Cancer Research. 80: 1-18. DOI: 10.1158/1538-7445.Sabcs19-P1-18-10  0.522
2020 Dahlgren M, George AM, Brueffer C, Gladchuk S, Chen Y, Vallon-Christersson J, Hegardt C, Häkkinen J, Rydén L, Malmberg M, Larsson C, Gruvberger-Saal SK, Ehinger A, Loman N, Borg Å, ... Saal LH, et al. Abstract CT074: Pre-existing ESR1 mutations in early-stage primary breast cancer predict failure of endocrine therapy and poor survival Cancer Research. 80. DOI: 10.1158/1538-7445.Am2020-Ct074  0.541
2019 Staaf J, Glodzik D, Bosch A, Vallon-Christersson J, Reuterswärd C, Häkkinen J, Degasperi A, Amarante TD, Saal LH, Hegardt C, Stobart H, Ehinger A, Larsson C, Rydén L, Loman N, et al. Whole-genome sequencing of triple-negative breast cancers in a population-based clinical study. Nature Medicine. PMID 31570822 DOI: 10.1038/S41591-019-0582-4  0.494
2019 Johnson K, Zackrisson S, Rosso A, Sartor H, Saal LH, Andersson I, Lång K. Tumor Characteristics and Molecular Subtypes in Breast Cancer Screening with Digital Breast Tomosynthesis: The Malmö Breast Tomosynthesis Screening Trial. Radiology. 190132. PMID 31478799 DOI: 10.1148/Radiol.2019190132  0.52
2019 Vallon-Christersson J, Häkkinen J, Hegardt C, Saal LH, Larsson C, Ehinger A, Lindman H, Olofsson H, Sjöblom T, Wärnberg F, Ryden L, Loman N, Malmberg M, Borg Å, Staaf J. Cross comparison and prognostic assessment of breast cancer multigene signatures in a large population-based contemporary clinical series. Scientific Reports. 9: 12184. PMID 31434940 DOI: 10.1038/S41598-019-48570-X  0.434
2019 Lundgren C, Bendahl PO, Borg Å, Ehinger A, Hegardt C, Larsson C, Loman N, Malmberg M, Olofsson H, Saal LH, Sjöblom T, Lindman H, Klintman M, Häkkinen J, Vallon-Christersson J, et al. Agreement between molecular subtyping and surrogate subtype classification: a contemporary population-based study of ER-positive/HER2-negative primary breast cancer. Breast Cancer Research and Treatment. PMID 31432367 DOI: 10.1007/S10549-019-05378-7  0.475
2019 Dihge L, Vallon-Christersson J, Hegardt C, Saal LH, Häkkinen J, Larsson C, Ehinger A, Loman N, Malmberg M, Bendahl PO, Borg A, Staaf J, Rydén L. Prediction of lymph node metastasis in breast cancer by gene expression and clinicopathological models: Development and validation within a population based cohort. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31340938 DOI: 10.1158/1078-0432.Ccr-19-0075  0.438
2019 Förnvik D, Aaltonen KE, Chen Y, George AM, Brueffer C, Rigo R, Loman N, Saal LH, Rydén L. Detection of circulating tumor cells and circulating tumor DNA before and after mammographic breast compression in a cohort of breast cancer patients scheduled for neoadjuvant treatment. Breast Cancer Research and Treatment. PMID 31236809 DOI: 10.1007/S10549-019-05326-5  0.505
2019 Isaksson S, George AM, Jönsson M, Cirenajwis H, Jönsson P, Bendahl PO, Brunnström H, Staaf J, Saal LH, Planck M. Pre-operative plasma cell-free circulating tumor DNA and serum protein tumor markers as predictors of lung adenocarcinoma recurrence. Acta Oncologica (Stockholm, Sweden). 1-8. PMID 31230502 DOI: 10.1080/0284186X.2019.1610573  0.414
2019 Søkilde R, Persson H, Ehinger A, Pirona AC, Fernö M, Hegardt C, Larsson C, Loman N, Malmberg M, Rydén L, Saal L, Borg Å, Vallon-Christerson J, Rovira C. Refinement of breast cancer molecular classification by miRNA expression profiles. Bmc Genomics. 20: 503. PMID 31208318 DOI: 10.1186/S12864-019-5887-7  0.488
2019 Bosch A, Larsson A, Holm K, Borg Å, Staaf J, Saal L. SCAN-B-rec: Infrastructure, technology and clinical research platform to profile and monitor metastatic breast cancer Annals of Oncology. 30: iii25. DOI: 10.1093/Annonc/Mdz095.078  0.446
2018 Brueffer C, Vallon-Christersson J, Grabau D, Ehinger A, Häkkinen J, Hegardt C, Malina J, Chen Y, Bendahl PO, Manjer J, Malmberg M, Larsson C, Loman N, Rydén L, Borg Å, ... Saal LH, et al. Clinical Value of RNA Sequencing-Based Classifiers for Prediction of the Five Conventional Breast Cancer Biomarkers: A Report From the Population-Based Multicenter Sweden Cancerome Analysis Network-Breast Initiative. Jco Precision Oncology. 2. PMID 32913985 DOI: 10.1200/PO.17.00135  0.377
2018 Chen Y, George AM, Olsson E, Saal LH. Identification and Use of Personalized Genomic Markers for Monitoring Circulating Tumor DNA. Methods in Molecular Biology (Clifton, N.J.). 1768: 303-322. PMID 29717450 DOI: 10.1007/978-1-4939-7778-9_17  0.417
2018 Roswall P, Bocci M, Bartoschek M, Li H, Kristiansen G, Jansson S, Lehn S, Sjölund J, Reid S, Larsson C, Eriksson P, Anderberg C, Cortez E, Saal LH, Orsmark-Pietras C, et al. Microenvironmental control of breast cancer subtype elicited through paracrine platelet-derived growth factor-CC signaling. Nature Medicine. PMID 29529015 DOI: 10.1038/Nm.4494  0.57
2018 Zardavas D, Te Marvelde L, Milne RL, Fumagalli D, Fountzilas G, Kotoula V, Razis E, Papaxoinis G, Joensuu H, Moynahan ME, Hennessy BT, Bieche I, Saal LH, Stal O, Iacopetta B, et al. Tumor PIK3CA Genotype and Prognosis in Early-Stage Breast Cancer: A Pooled Analysis of Individual Patient Data. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2017748301. PMID 29470143 DOI: 10.1200/Jco.2017.74.8301  0.506
2018 Rydén L, Loman N, Larsson C, Hegardt C, Vallon-Christersson J, Malmberg M, Lindman H, Ehinger A, Saal LH, Borg Å. Minimizing inequality in access to precision medicine in breast cancer by real-time population-based molecular analysis in the SCAN-B initiative. The British Journal of Surgery. 105: e158-e168. PMID 29341157 DOI: 10.1002/Bjs.10741  0.511
2018 Brueffer C, Vallon-Christersson J, Grabau D, Ehinger A, Häkkinen J, Hegardt C, Malina J, Chen Y, Bendahl P, Manjer J, Malmberg M, Larsson C, Loman N, Rydén L, Borg Å, ... Saal L, et al. Abstract P4-09-03: On the development and clinical value of RNA-sequencing-based classifiers for prediction of the five conventional breast cancer biomarkers: A report from the population-based multicenter SCAN-B study Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P4-09-03  0.46
2018 Morgan G, Larsson C, Tahin B, Vallon-Christersson J, Häkkinen J, Ehinger A, Malmberg M, Hegardt C, Borg Å, Rydén L, Saal L, Hedenfalk I, Loman N. Abstract P3-02-02: Concordance between immunohistochemical and gene-expression based subtyping of early breast cancer using core needle biopsies and surgical specimens - experices from SCAN-B Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P3-02-02  0.445
2018 Loman N, Chen Y, Aaltonen K, Brueffer C, George A, Zander L, Vallon-Christersson J, Häkkinen J, Förnvik D, Rigo R, Ehinger A, Malmberg M, Larsson C, Hegardt C, Borg Å, ... ... Saal L, et al. Abstract P2-02-09: Breast cancer subtype distribution and circulating tumor DNA in response to neoadjuvant chemotherapy: Experiences from a preoperative cohort within SCAN-B Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P2-02-09  0.5
2018 Staaf J, Vallon-Christersson J, Häkkinen J, Saal L, Hegardt C, Larsson C, Ehinger A, Rydén L, Loman N, Malmberg M, Borg Å. Abstract P1-06-01: Putting multigene signatures to the test: Prognostic assessment in population-based contemporary clinical breast cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P1-06-01  0.519
2018 Isaksson S, George A, Jönsson M, Cirenajwis H, Brunnström H, Jönsson P, Staaf J, Saal L, Planck M. 94P Lung cancer recurrence in patients with preoperative circulating tumor DNA and elevated tumor markers Journal of Thoracic Oncology. 13: S52-S53. DOI: 10.1016/S1556-0864(18)30369-1  0.429
2017 Nilsson MP, Emmertz M, Kristoffersson U, Borg Å, Larsson C, Rehn M, Winter C, Saal LH, Brandberg Y, Loman N. Germline mutations in BRCA1 and BRCA2 incidentally revealed in a biobank research study: experiences from re-contacting mutation carriers and relatives. Journal of Community Genetics. PMID 29082482 DOI: 10.1007/S12687-017-0341-5  0.319
2017 Pappas K, Xu J, Zairis S, Resnick-Silverman L, Abate F, Steinbach N, Ozturk S, Saal LH, Su T, Cheung P, Schmidt H, Aaronson SA, Hibshoosh H, Manfredi JJ, Rabadan R, et al. p53 maintains baseline expression of multiple tumor suppressor genes. Molecular Cancer Research : McR. PMID 28483946 DOI: 10.1158/1541-7786.Mcr-17-0089  0.649
2017 Cirenajwis H, Lauss M, Ekedahl H, Törngren T, Kvist A, Saal LH, Olsson H, Staaf J, Carneiro A, Ingvar C, Harbst K, Hayward NK, Jönsson G. NF1-mutated melanoma tumors harbor distinct clinical and biological characteristics. Molecular Oncology. PMID 28267273 DOI: 10.1002/1878-0261.12050  0.421
2017 Nilsson MP, Winter C, Kristoffersson U, Rehn M, Larsson C, Saal LH, Loman N. Efficacy versus effectiveness of clinical genetic testing criteria for BRCA1 and BRCA2 hereditary mutations in incident breast cancer. Familial Cancer. PMID 28120249 DOI: 10.1007/S10689-016-9953-X  0.478
2017 Saal L, Hegardt C, Vallon-Christersson J, Häkkinen J, Ehinger A, Manjer J, Larsson C, Loman N, Rydén L, Malmberg M, Borg Å. Abstract P1-07-17: The SCAN-B study: 5-year summary of a large-scale population-based prospective breast cancer translational genomics platform covering a wide geography of Sweden (NCT02306096) Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P1-07-17  0.548
2017 Ehinger A, Remse I, Lövgren K, Hegardt C, Häkkinen J, Saal L, Vallon-Christersson J, Borg Å. Myoepithelium assessment with p63 immunostaining in formalinfixed paraffin-embedded breast cancer tissue pre-treated with RNA-later Virchows Archiv. 471: 299-299. DOI: 10.1007/S00428-017-2205-0  0.422
2016 Whale AS, Devonshire AS, Karlin-Neumann GA, Regan J, Javier L, Cowen S, Fernandez-Gonzalez A, Jones GM, Redshaw N, Beck J, Berger AW, Combaret V, Dahl Kjersgaard N, Davis L, Fina F, ... ... Saal LH, et al. AN INTERNATIONAL INTER-LABORATORY DIGITAL PCR STUDY DEMONSTRATES HIGH REPRODUCIBILITY FOR THE MEASUREMENT OF A RARE SEQUENCE VARIANT. Analytical Chemistry. PMID 27935690 DOI: 10.1021/Acs.Analchem.6B03980  0.302
2016 Loman N, Saal LH. The state of the art in prediction of breast cancer relapse using cell-free circulating tumor DNA liquid biopsies. Annals of Translational Medicine. 4: S68. PMID 27868036 DOI: 10.21037/Atm.2016.10.58  0.531
2016 She QB, Gruvberger-Saal SK, Maurer M, Chen Y, Jumppanen M, Su T, Dendy M, Lau YK, Memeo L, Horlings HM, van de Vijver MJ, Isola J, Hibshoosh H, Rosen N, Parsons R, ... Saal LH, et al. Integrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer. Bmc Cancer. 16: 587. PMID 27484095 DOI: 10.1186/S12885-016-2609-2  0.674
2016 Winter C, Nilsson MP, Olsson E, George AM, Chen Y, Kvist A, Törngren T, Vallon-Christersson J, Hegardt C, Häkkinen J, Jönsson G, Grabau D, Malmberg M, Kristoffersson U, Rehn M, ... ... Saal LH, et al. Targeted sequencing of BRCA1 and BRCA2 across a large unselected breast cancer cohort suggests one third of mutations are somatic. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. PMID 27194814 DOI: 10.1093/Annonc/Mdw209  0.521
2016 Lasič S, Oredsson S, Partridge SC, Saal LH, Topgaard D, Nilsson M, Bryskhe K. Apparent exchange rate for breast cancer characterization. Nmr in Biomedicine. PMID 26929050 DOI: 10.1002/Nbm.3504  0.49
2016 Lasič S, Oredsson S, Partridge SC, Saal LH, Topgaard D, Nilsson M, Bryskhe K. Apparent exchange rate for breast cancer characterization Nmr in Biomedicine. DOI: 10.1002/nbm.3504  0.395
2015 Olsson E, Winter C, George A, Chen Y, Törngren T, Bendahl PO, Borg Å, Gruvberger-Saal SK, Saal LH. Mutation Screening of 1,237 Cancer Genes across Six Model Cell Lines of Basal-Like Breast Cancer. Plos One. 10: e0144528. PMID 26670335 DOI: 10.1371/Journal.Pone.0144528  0.462
2015 Tang ME, Dahlgren M, Brueffer C, Tjitrowirjo T, Winter C, Chen Y, Olsson E, Wang K, Törngren T, Sjöström M, Grabau D, Bendahl PO, Rydén L, Niméus E, Saal LH, et al. Remarkable similarities of chromosomal rearrangements between primary human breast cancers and matched distant metastases as revealed by whole-genome sequencing. Oncotarget. PMID 26439695 DOI: 10.18632/Oncotarget.5951  0.499
2015 Mehmeti M, Allaoui R, Bergenfelz C, Saal LH, Ethier SP, Johansson ME, Jirström K, Leandersson K. Expression of functional toll like receptor 4 in estrogen receptor/progesterone receptor-negative breast cancer. Breast Cancer Research : Bcr. 17: 130. PMID 26392082 DOI: 10.1186/S13058-015-0640-X  0.336
2015 Chen Y, van de Vijver MJ, Hibshoosh H, Parsons R, Saal LH. PTEN and NEDD4 in Human Breast Carcinoma. Pathology Oncology Research : Por. PMID 26276352 DOI: 10.1007/S12253-015-9971-2  0.694
2015 Alkner S, Tang MH, Brueffer C, Dahlgren M, Chen Y, Olsson E, Winter C, Baker S, Ehinger A, Rydén L, Saal LH, Fernö M, Gruvberger-Saal SK. Contralateral breast cancer can represent a metastatic spread of the first primary tumor: determination of clonal relationship between contralateral breast cancers using next-generation whole genome sequencing. Breast Cancer Research : Bcr. 17: 102. PMID 26242876 DOI: 10.1186/S13058-015-0608-X  0.554
2015 Olsson E, Winter C, George A, Chen Y, Howlin J, Tang MH, Dahlgren M, Schulz R, Grabau D, van Westen D, Fernö M, Ingvar C, Rose C, Bendahl PO, Rydén L, ... ... Saal LH, et al. Serial monitoring of circulating tumor DNA in patients with primary breast cancer for detection of occult metastatic disease. Embo Molecular Medicine. PMID 25987569 DOI: 10.15252/Emmm.201404913  0.515
2015 Cirenajwis H, Ekedahl H, Lauss M, Harbst K, Carneiro A, Enoksson J, Rosengren F, Werner-Hartman L, Törngren T, Kvist A, Fredlund E, Bendahl PO, Jirström K, Lundgren L, Howlin J, ... ... Saal LH, et al. Molecular stratification of metastatic melanoma using gene expression profiling: Prediction of survival outcome and benefit from molecular targeted therapy. Oncotarget. 6: 12297-309. PMID 25909218 DOI: 10.18632/Oncotarget.3655  0.383
2015 Howlin J, Cirenajwis H, Lettiero B, Staaf J, Lauss M, Saal L, Borg K, Gruvberger-Saal S, Jönsson G. Loss of CITED1, an MITF regulator, drives a phenotype switch in vitro and can predict clinical outcome in primary melanoma tumours. Peerj. 3: e788. PMID 25755924 DOI: 10.7717/Peerj.788  0.365
2015 Saal LH, Vallon-Christersson J, Häkkinen J, Hegardt C, Grabau D, Winter C, Brueffer C, Tang MH, Reuterswärd C, Schulz R, Karlsson A, Ehinger A, Malina J, Manjer J, Malmberg M, et al. The Sweden Cancerome Analysis Network - Breast (SCAN-B) Initiative: a large-scale multicenter infrastructure towards implementation of breast cancer genomic analyses in the clinical routine. Genome Medicine. 7: 20. PMID 25722745 DOI: 10.1186/S13073-015-0131-9  0.483
2015 Zardavas D, Marvelde LT, Milne R, Joensuu H, Moynahan ME, Hennessy B, Bieche I, Saal LH, Stal O, Iacopetta B, Jensen JD, O'Toole S, Barbareschi M, Noguchi S, Lerma E, et al. Tumor PIK3CA genotype and prognosis: A pooled analysis of 4,241 patients (pts) with early-stage breast cancer (BC) Journal of Clinical Oncology. 33: 516-516. DOI: 10.1200/Jco.2015.33.15_Suppl.516  0.444
2015 Tang M, Dahlgren M, Brueffer C, Winter C, Chen Y, Olsson E, Sjöström M, Bendahl P, Niméus-Malmström E, Saal LH, Borg Å, Gruvberger-Saal SK. Abstract 4805: Whole genome sequencing of primary breast cancers and matched distant metastases Molecular and Cellular Biology. DOI: 10.1158/1538-7445.Am2015-4805  0.465
2014 Harbst K, Lauss M, Cirenajwis H, Winter C, Howlin J, Törngren T, Kvist A, Nodin B, Olsson E, Häkkinen J, Jirström K, Staaf J, Lundgren L, Olsson H, Ingvar C, ... ... Saal LH, et al. Molecular and genetic diversity in the metastatic process of melanoma. The Journal of Pathology. 233: 39-50. PMID 24399611 DOI: 10.1002/Path.4318  0.368
2013 Pires MM, Hopkins BD, Saal LH, Parsons RE. Alterations of EGFR, p53 and PTEN that mimic changes found in basal-like breast cancer promote transformation of human mammary epithelial cells. Cancer Biology & Therapy. 14: 246-53. PMID 23291982 DOI: 10.4161/Cbt.23297  0.775
2013 Olsson E, Winter C, George A, Chen Y, Tang ME, Dahlgren M, Schulz R, Fernö M, Rose C, Howlin J, Ingvar C, Rydén L, Borg Å, Gruvberger-Saal SK, Jernström H, ... Saal LH, et al. Abstract LB-77: Measurement of tumor-specific chromosomal rearrangements in serial blood samples to monitor breast cancer burden and detect occult metastasis. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-77  0.497
2013 Saal LH, She Q, Gruvberger-Saal SK, Maurer M, Jumppanen M, Su T, Dendy M, Lau YI, Memeo L, Ringner M, Isola J, Hibshoosh H, Rosen N, Parsons R. Abstract 869: PTEN/PI3K oncogenic pathway profiling informs an in vivo synergistic therapeutic model for basal-like breast cancer. Cancer Research. 73: 869-869. DOI: 10.1158/1538-7445.Am2013-869  0.716
2012 Holm K, Grabau D, Lövgren K, Aradottir S, Gruvberger-Saal S, Howlin J, Saal LH, Ethier SP, Bendahl PO, Stål O, Malmström P, Fernö M, Rydén L, Hegardt C, Borg Å, et al. Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes. Molecular Oncology. 6: 494-506. PMID 22766277 DOI: 10.1016/J.Molonc.2012.06.002  0.58
2012 Jönsson G, Staaf J, Vallon-Christersson J, Ringnér M, Gruvberger-Saal SK, Saal LH, Holm K, Hegardt C, Arason A, Fagerholm R, Persson C, Grabau D, Johnsson E, Lövgren K, Magnusson L, et al. The retinoblastoma gene undergoes rearrangements in BRCA1-deficient basal-like breast cancer. Cancer Research. 72: 4028-36. PMID 22706203 DOI: 10.1158/0008-5472.Can-12-0097  0.573
2011 Olsson E, Honeth G, Bendahl PO, Saal LH, Gruvberger-Saal S, Ringnér M, Vallon-Christersson J, Jönsson G, Holm K, Lövgren K, Fernö M, Grabau D, Borg A, Hegardt C. CD44 isoforms are heterogeneously expressed in breast cancer and correlate with tumor subtypes and cancer stem cell markers. Bmc Cancer. 11: 418. PMID 21957977 DOI: 10.1186/1471-2407-11-418  0.514
2011 Loman N, Saal L, Häkkinen J, Vallon-Christersson J, Ringnér M, Hegardt C, Jönsson G, Gruvberger-Saal S, Kvist A, Reuterswärd C, Schulz R, Karlsson A, Jönsson M, Grabau D, Manjer J, et al. P3-06-08: SCAN-B: An Accelerated Translational Pipeline from Profile to Prognosis and Prediction for Individual Breast Cancer Patients. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P3-06-08  0.513
2009 Fine B, Hodakoski C, Koujak S, Su T, Saal LH, Maurer M, Hopkins B, Keniry M, Sulis ML, Mense S, Hibshoosh H, Parsons R. Activation of the PI3K pathway in cancer through inhibition of PTEN by exchange factor P-REX2a. Science (New York, N.Y.). 325: 1261-5. PMID 19729658 DOI: 10.1126/Science.1173569  0.684
2009 Maurer M, Su T, Saal LH, Koujak S, Hopkins BD, Barkley CR, Wu J, Nandula S, Dutta B, Xie Y, Chin YR, Kim DI, Ferris JS, Gruvberger-Saal SK, Laakso M, et al. 3-Phosphoinositide-dependent kinase 1 potentiates upstream lesions on the phosphatidylinositol 3-kinase pathway in breast carcinoma. Cancer Research. 69: 6299-306. PMID 19602588 DOI: 10.1158/0008-5472.Can-09-0820  0.679
2008 Honeth G, Bendahl PO, Ringnér M, Saal LH, Gruvberger-Saal SK, Lövgren K, Grabau D, Fernö M, Borg A, Hegardt C. The CD44+/CD24- phenotype is enriched in basal-like breast tumors. Breast Cancer Research : Bcr. 10: R53. PMID 18559090 DOI: 10.1186/Bcr2108  0.465
2008 Saal LH, Gruvberger-Saal SK, Persson C, Lövgren K, Jumppanen M, Staaf J, Jönsson G, Pires MM, Maurer M, Holm K, Koujak S, Subramaniyam S, Vallon-Christersson J, Olsson H, Su T, et al. Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair. Nature Genetics. 40: 102-7. PMID 18066063 DOI: 10.1038/Ng.2007.39  0.769
2007 Persson O, Krogh M, Saal LH, Englund E, Liu J, Parsons R, Mandahl N, Borg A, Widegren B, Salford LG. Microarray analysis of gliomas reveals chromosomal position-associated gene expression patterns and identifies potential immunotherapy targets. Journal of Neuro-Oncology. 85: 11-24. PMID 17634744 DOI: 10.1007/S11060-007-9383-6  0.587
2007 Saal LH, Johansson P, Holm K, Gruvberger-Saal SK, She QB, Maurer M, Koujak S, Ferrando AA, Malmström P, Memeo L, Isola J, Bendahl PO, Rosen N, Hibshoosh H, Ringnér M, et al. Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity. Proceedings of the National Academy of Sciences of the United States of America. 104: 7564-9. PMID 17452630 DOI: 10.1073/Pnas.0702507104  0.672
2007 Gruvberger-Saal SK, Bendahl PO, Saal LH, Laakso M, Hegardt C, Edén P, Peterson C, Malmström P, Isola J, Borg A, Fernö M. Estrogen receptor beta expression is associated with tamoxifen response in ERalpha-negative breast carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 1987-94. PMID 17404078 DOI: 10.1158/1078-0432.Ccr-06-1823  0.537
2005 Saal LH, Holm K, Maurer M, Memeo L, Su T, Wang X, Yu JS, Malmström PO, Mansukhani M, Enoksson J, Hibshoosh H, Borg A, Parsons R. PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma. Cancer Research. 65: 2554-9. PMID 15805248 DOI: 10.1158/0008-5472-Can-04-3913  0.674
2002 Khan J, Saal LH, Bittner ML, Jiang Y, Gooden GC, Glatfelter AA, Meltzer PS. Gene expression profiling in cancer using cDNA microarrays. Methods in Molecular Medicine. 68: 205-222. PMID 11901504 DOI: 10.1385/1-59259-135-3:205  0.412
2001 Gruvberger S, Ringnér M, Chen Y, Panavally S, Saal LH, Borg A, Fernö M, Peterson C, Meltzer PS. Estrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns Cancer Research. 61: 5979-5984. PMID 11507038  0.362
2001 Khan J, Wei JS, Ringnér M, Saal LH, Ladanyi M, Westermann F, Berthold F, Schwab M, Antonescu CR, Peterson C, Meltzer PS. Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks Nature Medicine. 7: 673-679. PMID 11385503 DOI: 10.1038/89044  0.41
2001 Khan J, Wei J, Saal L, Marc L, Markus R, Peterson C, Chen Y, Meltzer P. Development of a molecular taxonomy of small blue round-cell tumors using cDNA microarrays Nature Genetics. 27: 64-64. DOI: 10.1038/87150  0.363
1999 Khan J, Bittner ML, Saal LH, Teichmann U, Azorsa DO, Gooden GC, Pavan WJ, Trent JM, Meltzer PS. cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene Proceedings of the National Academy of Sciences of the United States of America. 96: 13264-13269. PMID 10557309 DOI: 10.1073/Pnas.96.23.13264  0.319
1999 Khan J, Saal LH, Bittner ML, Chen Y, Trent JM, Meltzer PS. Expression profiling in cancer using cDNA microarrays Electrophoresis. 20: 223-229. PMID 10197427 DOI: 10.1002/(Sici)1522-2683(19990201)20:2<223::Aid-Elps223>3.0.Co;2-A  0.351
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