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Derek W. Cain, Ph.D. - Publications

Affiliations: 
2010 Immunology Duke University, Durham, NC 
Area:
Immunology
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30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Li D, Bradley T, Cain DW, Pedroza-Pacheco I, Aggelakopoulou M, Parks R, Barr M, Xia SM, Scearce R, Bowman C, Stevens G, Newman A, Hora B, Chen Y, Riebe K, et al. -Deficient Mice Exhibit Cytokine-Related Transcriptomic Signatures. Immunohorizons. 4: 713-728. PMID 33172842 DOI: 10.4049/immunohorizons.2000088  0.325
2020 Tian M, McGovern K, Cheng HL, Waddicor P, Rieble L, Dao M, Chen Y, Kimble MT, Cantor E, Manfredonia N, Judson R, Chapdelaine-Williams A, Cain DW, Haynes BF, Alt FW. Conditional antibody expression to avoid central B cell deletion in humanized HIV-1 vaccine mouse models. Proceedings of the National Academy of Sciences of the United States of America. PMID 32209668 DOI: 10.1073/Pnas.1921996117  0.382
2020 Bradley T, Kuraoka M, Yeh CH, Tian M, Chen H, Cain DW, Chen X, Cheng C, Ellebedy AH, Parks R, Barr M, Sutherland LL, Scearce RM, Bowman CM, Bouton-Verville H, et al. Immune checkpoint modulation enhances HIV-1 antibody induction. Nature Communications. 11: 948. PMID 32075963 DOI: 10.1038/S41467-020-14670-W  0.706
2020 Han Q, Bradley T, Williams WB, Cain DW, Montefiori DC, Saunders KO, Parks RJ, Edwards RW, Ferrari G, Mueller O, Shen X, Wiehe KJ, Reed S, Fox CB, Rountree W, et al. Neonatal Rhesus Macaques Have Distinct Immune Cell Transcriptional Profiles following HIV Envelope Immunization. Cell Reports. 30: 1553-1569.e6. PMID 32023469 DOI: 10.1016/J.Celrep.2019.12.091  0.396
2019 Saunders KO, Wiehe K, Tian M, Acharya P, Bradley T, Alam SM, Go EP, Scearce R, Sutherland L, Henderson R, Hsu AL, Borgnia MJ, Chen H, Lu X, Wu NR, ... ... Cain DW, et al. Targeted selection of HIV-specific antibody mutations by engineering B cell maturation. Science (New York, N.Y.). 366. PMID 31806786 DOI: 10.1126/Science.Aay7199  0.343
2019 Nelson AN, Goswami R, Dennis M, Tu J, Mangan RJ, Saha PT, Cain DW, Curtis AD, Shen X, Shaw GM, Bar K, Hudgens M, Pollara J, De Paris K, Van Rompay KKA, et al. SHIV.CH505-infected infant and adult rhesus macaques exhibit similar HIV Env-specific antibody kinetics, despite distinct T-follicular helper (Tfh) and germinal center B cell landscapes. Journal of Virology. PMID 31092583 DOI: 10.1128/Jvi.00168-19  0.33
2019 Pardi N, LaBranche CC, Ferrari G, Cain DW, Tombácz I, Parks RJ, Muramatsu H, Mui BL, Tam YK, Karikó K, Polacino P, Barbosa CJ, Madden TD, Hope MJ, Haynes BF, et al. Characterization of HIV-1 Nucleoside-Modified mRNA Vaccines in Rabbits and Rhesus Macaques. Molecular Therapy. Nucleic Acids. 15: 36-47. PMID 30974332 DOI: 10.1016/J.Omtn.2019.03.003  0.337
2018 Bradley T, Peppa D, Pedroza-Pacheco I, Li D, Cain DW, Henao R, Venkat V, Hora B, Chen Y, Vandergrift NA, Overman RG, Edwards RW, Woods CW, Tomaras GD, Ferrari G, et al. RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses. Cell. PMID 30270043 DOI: 10.1016/J.Cell.2018.08.064  0.362
2018 Pardi N, Hogan MJ, Naradikian MS, Parkhouse K, Cain DW, Jones L, Moody MA, Verkerke HP, Myles A, Willis E, LaBranche CC, Montefiori DC, Lobby JL, Saunders KO, Liao HX, et al. Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses. The Journal of Experimental Medicine. PMID 29739835 DOI: 10.1084/Jem.20171450  0.397
2017 Saunders KO, Verkoczy LK, Jiang C, Zhang J, Parks R, Chen H, Housman M, Bouton-Verville H, Shen X, Trama AM, Scearce R, Sutherland L, Santra S, Newman A, Eaton A, ... ... Cain DW, et al. Vaccine Induction of Heterologous Tier 2 HIV-1 Neutralizing Antibodies in Animal Models. Cell Reports. 21: 3681-3690. PMID 29281818 DOI: 10.1016/J.Celrep.2017.12.028  0.349
2017 Azzam KM, Madenspacher JH, Cain DW, Lai L, Gowdy KM, Rai P, Janardhan K, Clayton N, Cunningham W, Jensen H, Patel PS, Kearney JF, Taylor GA, Fessler MB. Irgm1 coordinately regulates autoimmunity and host defense at select mucosal surfaces. Jci Insight. 2. PMID 28814662 DOI: 10.1172/Jci.Insight.91914  0.35
2016 Abbott RK, Silva M, Labuda J, Thayer M, Cain DW, Philbrook P, Sethumadhavan S, Hatfield S, Ohta A, Sitkovsky M. The GS protein coupled A2a adenosine receptor controls T cell help in the germinal center. The Journal of Biological Chemistry. PMID 27974461 DOI: 10.1074/Jbc.C116.764043  0.417
2016 Abbott RK, Thayer M, Labuda J, Silva M, Philbrook P, Cain DW, Kojima H, Hatfield S, Sethumadhavan S, Ohta A, Reinherz EL, Kelsoe G, Sitkovsky M. Germinal Center Hypoxia Potentiates Immunoglobulin Class Switch Recombination. Journal of Immunology (Baltimore, Md. : 1950). PMID 27798169 DOI: 10.4049/Jimmunol.1601401  0.572
2016 Bortner CD, Scoltock AB, Cain DW, Cidlowski JA. T-cell development of resistance to apoptosis is driven by a metabolic shift in carbon source and altered activation of death pathways. Cell Death and Differentiation. 23: 889-902. PMID 26658018 DOI: 10.1038/Cdd.2015.156  0.338
2013 Cain DW, O'Koren EG, Kan MJ, Womble M, Sempowski GD, Hopper K, Gunn MD, Kelsoe G. Identification of a tissue-specific, C/EBPβ-dependent pathway of differentiation for murine peritoneal macrophages. Journal of Immunology (Baltimore, Md. : 1950). 191: 4665-75. PMID 24078688 DOI: 10.4049/Jimmunol.1300581  0.573
2013 Kim M, Song L, Moon J, Sun ZY, Bershteyn A, Hanson M, Cain D, Goka S, Kelsoe G, Wagner G, Irvine D, Reinherz EL. Immunogenicity of membrane-bound HIV-1 gp41 membrane-proximal external region (MPER) segments is dominated by residue accessibility and modulated by stereochemistry. The Journal of Biological Chemistry. 288: 31888-901. PMID 24047898 DOI: 10.1074/Jbc.M113.494609  0.542
2013 Yang G, Holl TM, Liu Y, Li Y, Lu X, Nicely NI, Kepler TB, Alam SM, Liao HX, Cain DW, Spicer L, VandeBerg JL, Haynes BF, Kelsoe G. Identification of autoantigens recognized by the 2F5 and 4E10 broadly neutralizing HIV-1 antibodies. The Journal of Experimental Medicine. 210: 241-56. PMID 23359068 DOI: 10.1084/Jem.20121977  0.535
2013 Cain DW, Sanders SE, Cunningham MM, Kelsoe G. Disparate adjuvant properties among three formulations of "alum". Vaccine. 31: 653-60. PMID 23200935 DOI: 10.1016/J.Vaccine.2012.11.044  0.574
2011 Kuraoka M, Holl TM, Liao D, Womble M, Cain DW, Reynolds AE, Kelsoe G. Activation-induced cytidine deaminase mediates central tolerance in B cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 11560-5. PMID 21700885 DOI: 10.1073/Pnas.1102571108  0.716
2011 Cain DW, Snowden PB, Sempowski GD, Kelsoe G. Inflammation triggers emergency granulopoiesis through a density-dependent feedback mechanism. Plos One. 6: e19957. PMID 21655273 DOI: 10.1371/Journal.Pone.0019957  0.648
2010 Kelsoe G, Cain D. A new guise for hyper-IgM syndrome. Blood. 116: 5785-6. PMID 21183692 DOI: 10.1182/Blood-2010-09-303404  0.49
2010 Ledford JG, Lo B, Kislan MM, Thomas JM, Evans K, Cain DW, Kraft M, Williams KL, Wright JR. Surfactant protein-A inhibits mycoplasma-induced dendritic cell maturation through regulation of HMGB-1 cytokine activity. Journal of Immunology (Baltimore, Md. : 1950). 185: 3884-94. PMID 20810986 DOI: 10.4049/Jimmunol.1000387  0.33
2010 Chen H, Liao D, Cain D, McLeod I, Ueda Y, Guan Z, Raetz C, Kelsoe G. Distinct granuloma responses in C57BL/6J and BALB/cByJ mice in response to pristane International Journal of Experimental Pathology. 91: 460-471. PMID 20681981 DOI: 10.1111/J.1365-2613.2010.00725.X  0.521
2009 Ueda Y, Cain DW, Kuraoka M, Kondo M, Kelsoe G. IL-1R type I-dependent hemopoietic stem cell proliferation is necessary for inflammatory granulopoiesis and reactive neutrophilia. Journal of Immunology (Baltimore, Md. : 1950). 182: 6477-84. PMID 19414802 DOI: 10.4049/Jimmunol.0803961  0.717
2009 Cain D, Kondo M, Chen H, Kelsoe G. Effects of acute and chronic inflammation on B-cell development and differentiation. The Journal of Investigative Dermatology. 129: 266-77. PMID 19148216 DOI: 10.1038/Jid.2008.286  0.584
2009 Cain D, Ueda Y, Holl T, Snowden P, Kondo M, Kelsoe G. T.20. Evidence for a Single Pathway of Neutrophil Production to Explain Both “Steady-state” and “Emergency” Granulopoiesis Clinical Immunology. 131: S56-S57. DOI: 10.1016/J.Clim.2009.03.161  0.625
2008 Sackstein R, Merzaban JS, Cain DW, Dagia NM, Spencer JA, Lin CP, Wohlgemuth R. Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone. Nature Medicine. 14: 181-7. PMID 18193058 DOI: 10.1038/Nm1703  0.318
2007 Schreiber TH, Shinder V, Cain DW, Alon R, Sackstein R. Shear flow-dependent integration of apical and subendothelial chemokines in T-cell transmigration: implications for locomotion and the multistep paradigm. Blood. 109: 1381-6. PMID 17038526 DOI: 10.1182/Blood-2006-07-032995  0.343
2007 Sackstein R, Merzaban JS, Cain DW, Dagia NM, Spencer JA, Lin CP, Wohlgemuth R. Ex Vivo Glycan Engineering of Membrane CD44 To Create HCELL Programs Human Mesenchymal Stem Cell Trafficking to Bone. Blood. 110: 218-218. DOI: 10.1182/Blood.V110.11.218.218  0.313
2005 Hamaguchi Y, Uchida J, Cain DW, Venturi GM, Poe JC, Haas KM, Tedder TF. The peritoneal cavity provides a protective niche for B1 and conventional B lymphocytes during anti-CD20 immunotherapy in mice. Journal of Immunology (Baltimore, Md. : 1950). 174: 4389-99. PMID 15778404 DOI: 10.4049/Jimmunol.174.7.4389  0.336
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