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Shen Shen, Ph.D. - Publications

Affiliations: 
2013 Biochemistry and Biophysics University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
General Biophysics, Biochemistry, Virology Biology
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12 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Asokan A, Shen S. Redirecting AAV vectors to extrahepatic tissues. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 37805712 DOI: 10.1016/j.ymthe.2023.10.005  0.552
2019 Maeder ML, Stefanidakis M, Wilson CJ, Baral R, Barrera LA, Bounoutas GS, Bumcrot D, Chao H, Ciulla DM, DaSilva JA, Dass A, Dhanapal V, Fennell TJ, Friedland AE, Giannoukos G, ... ... Shen S, et al. Development of a gene-editing approach to restore vision loss in Leber congenital amaurosis type 10. Nature Medicine. PMID 30664785 DOI: 10.1038/S41591-018-0327-9  0.382
2018 Shen S, Sanchez ME, Blomenkamp K, Corcoran EM, Marco E, Yudkoff CJ, Jiang H, Teckman JH, Bumcrot D, Albright CF. Amelioration of Alpha-1 Antitrypsin Deficiency Diseases with Genome Editing in Transgenic Mice. Human Gene Therapy. PMID 29641323 DOI: 10.1089/Hum.2017.227  0.39
2015 Friedland AE, Baral R, Singhal P, Loveluck K, Shen S, Sanchez M, Marco E, Gotta GM, Maeder ML, Kennedy EM, Kornepati AV, Sousa A, Collins MA, Jayaram H, Cullen BR, et al. Characterization of Staphylococcus aureus Cas9: a smaller Cas9 for all-in-one adeno-associated virus delivery and paired nickase applications. Genome Biology. 16: 257. PMID 26596280 DOI: 10.1186/S13059-015-0817-8  0.327
2015 Gori JL, Hsu PD, Maeder ML, Shen S, Welstead GG, Bumcrot D. Delivery and Specificity of CRISPR-Cas9 Genome Editing Technologies for Human Gene Therapy. Human Gene Therapy. 26: 443-51. PMID 26068008 DOI: 10.1089/Hum.2015.074  0.317
2015 Shen S, Berry GE, Castellanos Rivera RM, Cheung RY, Troupes AN, Brown SM, Kafri T, Asokan A. Functional analysis of the putative integrin recognition motif on adeno-associated virus 9. The Journal of Biological Chemistry. 290: 1496-504. PMID 25404742 DOI: 10.1074/Jbc.M114.608281  0.601
2015 Maeder ML, Shen S, Burnight ER, Gloskowski S, Mepani R, Friedland AE, Jayaram H, Gotta G, Tucker BA, Bumcrot D. 687. Therapeutic Correction of an LCA-Causing Splice Defect in the CEP290 Gene by CRISPR/Cas-Mediated Genome Editing Molecular Therapy. 23: S273-S274. DOI: 10.1016/S1525-0016(16)34296-4  0.368
2013 Shen S, Troupes AN, Pulicherla N, Asokan A. Multiple roles for sialylated glycans in determining the cardiopulmonary tropism of adeno-associated virus 4. Journal of Virology. 87: 13206-13. PMID 24067974 DOI: 10.1128/Jvi.02109-13  0.595
2013 Shen S, Horowitz ED, Troupes AN, Brown SM, Pulicherla N, Samulski RJ, Agbandje-McKenna M, Asokan A. Engraftment of a galactose receptor footprint onto adeno-associated viral capsids improves transduction efficiency. The Journal of Biological Chemistry. 288: 28814-23. PMID 23940044 DOI: 10.1074/Jbc.M113.482380  0.577
2012 Shen S, Bryant KD, Sun J, Brown SM, Troupes A, Pulicherla N, Asokan A. Glycan binding avidity determines the systemic fate of adeno-associated virus type 9. Journal of Virology. 86: 10408-17. PMID 22787229 DOI: 10.1128/Jvi.01155-12  0.605
2011 Pulicherla N, Shen S, Yadav S, Debbink K, Govindasamy L, Agbandje-McKenna M, Asokan A. Engineering liver-detargeted AAV9 vectors for cardiac and musculoskeletal gene transfer. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1070-8. PMID 21364538 DOI: 10.1038/Mt.2011.22  0.578
2011 Shen S, Bryant KD, Brown SM, Randell SH, Asokan A. Terminal N-linked galactose is the primary receptor for adeno-associated virus 9. The Journal of Biological Chemistry. 286: 13532-40. PMID 21330365 DOI: 10.1074/Jbc.M110.210922  0.586
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