| Year |
Citation |
Score |
| 2023 |
Lavorgna TR, Gressett TE, Chastain WH, Bix GJ. Perlecan: a review of its role in neurologic and musculoskeletal disease. Frontiers in Physiology. 14: 1189731. PMID 37324385 DOI: 10.3389/fphys.2023.1189731 |
0.376 |
|
| 2023 |
Morrison VE, Bix GJ. The meal Maketh the Microglia: Why studying microglial phagocytosis is critical to stroke research. Neurochemistry International. 164: 105488. PMID 36707032 DOI: 10.1016/j.neuint.2023.105488 |
0.347 |
|
| 2022 |
Biose IJ, Oremosu J, Bhatnagar S, Bix GJ. Correction to: Promising Cerebral Blood Flow Enhancers in Acute Ischemic Stroke. Translational Stroke Research. PMID 36522584 DOI: 10.1007/s12975-022-01110-8 |
0.343 |
|
| 2022 |
Biose IJ, Rutkai I, Clossen B, Gage G, Schechtman K, Adkisson HD, Bix GJ. Recombinant Human Perlecan DV and Its LG3 Subdomain Are Neuroprotective and Acutely Functionally Restorative in Severe Experimental Ischemic Stroke. Translational Stroke Research. PMID 36508132 DOI: 10.1007/s12975-022-01089-2 |
0.4 |
|
| 2022 |
Biose IJ, Oremosu J, Bhatnagar S, Bix GJ. Promising Cerebral Blood Flow Enhancers in Acute Ischemic Stroke. Translational Stroke Research. PMID 36394792 DOI: 10.1007/s12975-022-01100-w |
0.39 |
|
| 2022 |
Shi SX, Vodovoz SJ, Xiu Y, Liu N, Jiang Y, Katakam PVG, Bix G, Dumont AS, Wang X. T-Lymphocyte Interactions with the Neurovascular Unit: Implications in Intracerebral Hemorrhage. Cells. 11. PMID 35805099 DOI: 10.3390/cells11132011 |
0.319 |
|
| 2021 |
Maniskas ME, Roberts JM, Gorman A, Bix GJ, Fraser JF. Intra-arterial combination therapy for experimental acute ischemic stroke. Clinical and Translational Science. PMID 34463026 DOI: 10.1111/cts.13147 |
0.313 |
|
| 2021 |
Amruta N, Bix G. ATN-161 Ameliorates Ischemia/Reperfusion-induced Oxidative Stress, Fibro-inflammation, Mitochondrial damage, and Apoptosis-mediated Tight Junction Disruption in bEnd.3 Cells. Inflammation. PMID 34420157 DOI: 10.1007/s10753-021-01509-9 |
0.356 |
|
| 2021 |
Biose IJ, Rutkai I, Adkisson D, Clossen B, Gage G, Bix GJ. Abstract P755: Perlecan Lg3 is Neuroprotective and Functionally Restorative in Experimental Ischemic Stroke Stroke. 52. DOI: 10.1161/STR.52.SUPPL_1.P755 |
0.341 |
|
| 2020 |
Jiang Y, Liu N, Han J, Li Y, Spencer P, Vodovoz SJ, Ning MM, Bix G, Katakam PVG, Dumont AS, Wang X. Diabetes Mellitus/Poststroke Hyperglycemia: a Detrimental Factor for tPA Thrombolytic Stroke Therapy. Translational Stroke Research. PMID 33140258 DOI: 10.1007/s12975-020-00872-3 |
0.32 |
|
| 2020 |
Rahman AA, Amruta N, Pinteaux E, Bix GJ. Neurogenesis After Stroke: A Therapeutic Perspective. Translational Stroke Research. PMID 32862401 DOI: 10.1007/s12975-020-00841-w |
0.408 |
|
| 2020 |
Amruta N, Rahman AA, Pinteaux E, Bix G. Neuroinflammation and fibrosis in stroke: The good, the bad and the ugly. Journal of Neuroimmunology. 346: 577318. PMID 32682140 DOI: 10.1016/j.jneuroim.2020.577318 |
0.385 |
|
| 2020 |
Trout AL, Kahle MP, Roberts JM, Marcelo A, de Hoog L, Boychuk JA, Grupke SL, Berretta A, Gowing EK, Boychuk CR, Gorman AA, Edwards DN, Rutkai I, Biose IJ, Ishibashi-Ueda H, ... ... Bix GJ, et al. Perlecan Domain-V Enhances Neurogenic Brain Repair After Stroke in Mice. Translational Stroke Research. PMID 32253702 DOI: 10.1007/S12975-020-00800-5 |
0.519 |
|
| 2020 |
Biose IJ, Salmeron KE, Parker A, Stowe A, Bix G. Abstract TP116: Effect of Voluntary Physical Activity on Circulating LG3 and Its Impact on Ischemic Stroke Stroke. 51. DOI: 10.1161/STR.51.SUPPL_1.TP116 |
0.327 |
|
| 2019 |
Grewal P, Dobbs MR, Pennypacker K, Kryscio RJ, Kitzman P, Wolfe M, Elkins K, Bix GJ, Fraser JF. Evaluation of Patients with High National Institutes of Health Stroke Scale as Thrombectomy Candidates Using the Kentucky Appalachian Stroke Registry. Cerebrovascular Diseases (Basel, Switzerland). 48: 1-6. PMID 31851968 DOI: 10.1159/000504834 |
0.356 |
|
| 2019 |
Simpkins AN, Janowski M, Oz HS, Roberts J, Bix G, Doré S, Stowe AM. Biomarker Application for Precision Medicine in Stroke. Translational Stroke Research. PMID 31848851 DOI: 10.1007/s12975-019-00762-3 |
0.377 |
|
| 2019 |
Salmeron KE, Maniskas ME, Edwards DN, Wong R, Rajkovic I, Trout A, Rahman AA, Hamilton S, Fraser JF, Pinteaux E, Bix GJ. Interleukin 1 alpha administration is neuroprotective and neuro-restorative following experimental ischemic stroke. Journal of Neuroinflammation. 16: 222. PMID 31727174 DOI: 10.1186/S12974-019-1599-9 |
0.457 |
|
| 2019 |
Edwards DN, Salmeron K, Lukins DE, Trout AL, Fraser JF, Bix GJ. Integrin α5β1 inhibition by ATN-161 reduces neuroinflammation and is neuroprotective in ischemic stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X19880161. PMID 31575337 DOI: 10.1177/0271678X19880161 |
0.498 |
|
| 2019 |
Edwards DN, Bix GJ. The Inflammatory Response After Ischemic Stroke: Targeting β and β Integrins. Frontiers in Neuroscience. 13: 540. PMID 31191232 DOI: 10.3389/Fnins.2019.00540 |
0.452 |
|
| 2019 |
Kant R, Halder SK, Bix GJ, Milner R. Absence of endothelial α5β1 integrin triggers early onset of experimental autoimmune encephalomyelitis due to reduced vascular remodeling and compromised vascular integrity. Acta Neuropathologica Communications. 7: 11. PMID 30678721 DOI: 10.1186/S40478-019-0659-9 |
0.328 |
|
| 2019 |
Edwards DN, Bix GJ. Roles of blood-brain barrier integrins and extracellular matrix in stroke. American Journal of Physiology. Cell Physiology. 316: C252-C263. PMID 30462535 DOI: 10.1152/Ajpcell.00151.2018 |
0.511 |
|
| 2019 |
Roberts JM, Bix GJ. Abstract WP565: Inhibition of Alpha5Beta1 Integrin as a Novel Therapy for Experimental Vascular Dementia Stroke. 50. DOI: 10.1161/Str.50.Suppl_1.Wp565 |
0.398 |
|
| 2019 |
Edwards D, Salmeron K, Lukins D, Fraser JF, Bix GJ. Abstract TP120: Inhibition of α5β1 Integrin With the Small Peptide ATN-161 Reduces Inflammation, Stabilizes the Blood-Brain Barrier, and is Neuroprotective After Experimental Ischemic Stroke Stroke. 50. DOI: 10.1161/STR.50.SUPPL_1.TP120 |
0.37 |
|
| 2018 |
Fraser JF, Collier LA, Gorman AA, Martha SR, Salmeron KE, Trout AL, Edwards DN, Davis SM, Lukins DE, Alhajeri A, Grupke S, Roberts JM, Bix GJ, Pennypacker KR. The Blood And Clot Thrombectomy Registry And Collaboration (BACTRAC) protocol: novel method for evaluating human stroke. Journal of Neurointerventional Surgery. PMID 30064997 DOI: 10.1136/Neurintsurg-2018-014118 |
0.448 |
|
| 2018 |
Roberts JM, Maniskas ME, Bix GJ. Bilateral carotid artery stenosis causes unexpected early changes in brain extracellular matrix and blood-brain barrier integrity in mice. Plos One. 13: e0195765. PMID 29649307 DOI: 10.1371/Journal.Pone.0195765 |
0.364 |
|
| 2018 |
Bix GJ, Fraser JF, Mack WJ, Carmichael ST, Perez-Pinzon M, Offner H, Sansing L, Bosetti F, Ayata C, Pennypacker KR. Uncovering the Rosetta Stone: Report from the First Annual Conference on Key Elements in Translating Stroke Therapeutics from Pre-Clinical to Clinical. Translational Stroke Research. PMID 29633156 DOI: 10.1007/S12975-018-0628-9 |
0.447 |
|
| 2018 |
Goodman JM, Maniskas M, Salmeron K, Edwards D, Grohs G, Roberts J, Fraser J, Bix G. Abstract WP97: A Novel Behavioral Neuroscore Survey Improves Characterization of Experimental Ischemic Stroke in Mice Stroke. 49. DOI: 10.1161/Str.49.Suppl_1.Wp97 |
0.452 |
|
| 2018 |
Salmeron KE, Maniskas ME, Wong R, Trout AL, Edwards DN, Pinteaux E, Fraser JF, Bix GJ. Abstract TP95: Intra-arterial Interleukin-1 alpha is Well Tolerated and Neuroprotective After Experimental Ischemic Stroke Stroke. 49. DOI: 10.1161/Str.49.Suppl_1.Tp95 |
0.43 |
|
| 2018 |
Fraser JF, Kitzman P, Wolfe M, Elkins K, Bix GJ, Dobbs MR. Abstract TP6: Evaluation of Patients With High NIH Stroke Scale as Thrombectomy Candidates Using the Kentucky Appalachian Stroke Registry (KApSR) Stroke. 49. DOI: 10.1161/Str.49.Suppl_1.Tp6 |
0.461 |
|
| 2018 |
Salmeron KE, Edwards DN, Wong R, Roberts JM, Pinteaux E, Bix GJ. Abstract TP102: Delayed Interleukin-1 alpha Treatment is Profoundly Neuroreparative in Experimental Ischemic Stroke Stroke. 49. DOI: 10.1161/Str.49.Suppl_1.Tp102 |
0.424 |
|
| 2018 |
Edwards D, Salmeron K, Fraser JF, Bix GJ. Abstract TMP28: Inhibition of Integrin α 5 β 1 With the Small Peptide Atn-161 Reduces Infarct Volume and Improves Functional Recovery Through Reduction of Blood-brain Barrier Permeability Stroke. 49. DOI: 10.1161/Str.49.Suppl_1.Tmp28 |
0.469 |
|
| 2018 |
Fraser JF, Collier L, Gorman A, Salmeron K, Edwards D, Davis S, Alhajeri A, Grupke S, Roberts J, Bix GJ, Pennypacker K. Abstract TMP107: Blood and Clot Thrombectomy Registry and Collaboration (BACTRAC) Protocol: Novel Method for Evaluating Human Stroke Stroke. 49. DOI: 10.1161/Str.49.Suppl_1.Tmp107 |
0.464 |
|
| 2017 |
Fraser JF, Maniskas M, Trout A, Lukins D, Parker L, Stafford WL, Alhajeri A, Roberts J, Bix GJ. Intra-arterial verapamil post-thrombectomy is feasible, safe, and neuroprotective in stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X17705259. PMID 28429604 DOI: 10.1177/0271678X17705259 |
0.433 |
|
| 2017 |
Maniskas M, Trout A, Goodman J, Bix G, Fraser J. O-031 Combinational therapy following elvo in a mouse model of stroke demonstrates new frontiers in neuroprotection: the mavaric trial Journal of Neurointerventional Surgery. 9. DOI: 10.1136/Neurintsurg-2017-Snis.31 |
0.341 |
|
| 2016 |
Pennypacker KR, Bix G, Fraser JF. Correcting the Trajectory of Stroke Therapeutic Research. Translational Stroke Research. PMID 28039576 DOI: 10.1007/S12975-016-0517-Z |
0.44 |
|
| 2016 |
Maniskas ME, Roberts JM, Trueman R, Learoyd AE, Gorman A, Fraser JF, Bix GJ. Intra-arterial nitroglycerin as directed acute treatment in experimental ischemic stroke. Journal of Neurointerventional Surgery. PMID 28031354 DOI: 10.1136/Neurintsurg-2016-012793 |
0.469 |
|
| 2016 |
Parham CL, Shaw C, Auckland LD, Dickeson SK, Griswold-Prenner I, Bix G. Perlecan Domain V Inhibits Amyloid-β Induced Activation of the α2β1 Integrin-Mediated Neurotoxic Signaling Cascade. Journal of Alzheimer's Disease : Jad. PMID 27636841 DOI: 10.3233/Jad-160290 |
0.34 |
|
| 2016 |
Salmeron K, Aihara T, Redondo-Castro E, Pinteaux E, Bix GJ. IL-1alpha induces angiogenesis in brain endothelial cells in vitro: implications for brain angiogenesis after acute injury. Journal of Neurochemistry. 136: 573-580. PMID 26546397 DOI: 10.1111/Jnc.13422 |
0.404 |
|
| 2015 |
Roberts J, de Hoog L, Bix GJ. Mice deficient in endothelial α5 integrin are profoundly resistant to experimental ischemic stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26661237 DOI: 10.1177/0271678X15616979 |
0.503 |
|
| 2015 |
Maniskas ME, Roberts JM, Aron I, Fraser JF, Bix GJ. Stroke neuroprotection revisited: Intra-arterial verapamil is profoundly neuroprotective in experimental acute ischemic stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26661189 DOI: 10.1177/0271678X15608395 |
0.471 |
|
| 2015 |
Grupke S, Hall J, Dobbs M, Bix GJ, Fraser JF. Understanding history, and not repeating it. Neuroprotection for acute ischemic stroke: from review to preview. Clinical Neurology and Neurosurgery. 129: 1-9. PMID 25497127 DOI: 10.1016/J.Clineuro.2014.11.013 |
0.457 |
|
| 2015 |
Maniskas M, Bix G, Fraser J. Selective intra-arterial drug administration in a model of large vessel ischemia Journal of Neuroscience Methods. 240: 22-27. PMID 25445249 DOI: 10.1016/J.Jneumeth.2014.10.015 |
0.45 |
|
| 2015 |
Marcelo A, Bix G. The potential role of perlecan domain V as novel therapy in vascular dementia. Metabolic Brain Disease. 30: 1-5. PMID 24964971 DOI: 10.1007/S11011-014-9576-6 |
0.38 |
|
| 2014 |
Guell K, Bix GJ. Brain endothelial cell specific integrins and ischemic stroke. Expert Review of Neurotherapeutics. 14: 1287-92. PMID 25262658 DOI: 10.1586/14737175.2014.964210 |
0.528 |
|
| 2014 |
Jullienne A, Roberts JM, Pop V, Paul Murphy M, Head E, Bix GJ, Badaut J. Juvenile traumatic brain injury induces long-term perivascular matrix changes alongside amyloid-beta accumulation. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 34: 1637-45. PMID 25052558 DOI: 10.1038/Jcbfm.2014.124 |
0.343 |
|
| 2014 |
Marcelo A, Bix G. Investigating the role of perlecan domain V in post-ischemic cerebral angiogenesis. Methods of Molecular Biology. 1135: 331-341. PMID 24510876 DOI: 10.1007/978-1-4939-0320-7_27 |
0.539 |
|
| 2014 |
Badaut J, Bix GJ. Vascular neural network phenotypic transformation after traumatic injury: potential role in long-term sequelae. Translational Stroke Research. 5: 394-406. PMID 24323723 DOI: 10.1007/S12975-013-0304-Z |
0.378 |
|
| 2014 |
Parham C, Auckland L, Rachwal J, Clarke D, Bix G. Perlecan domain V inhibits amyloid-β induced brain endothelial cell toxicity and restores angiogenic function. Journal of Alzheimer's Disease : Jad. 38: 415-23. PMID 23979025 DOI: 10.3233/Jad-130683 |
0.371 |
|
| 2013 |
Bix GJ, Gowing EK, Clarkson AN. Perlecan domain V is neuroprotective and affords functional improvement in a photothrombotic stroke model in young and aged mice. Translational Stroke Research. 4: 515-23. PMID 24323378 DOI: 10.1007/S12975-013-0266-1 |
0.457 |
|
| 2013 |
Steelman SM, Hein TW, Gorman A, Bix GJ. Effects of histidine-rich glycoprotein on cerebral blood vessels. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 1373-5. PMID 23801240 DOI: 10.1038/Jcbfm.2013.106 |
0.39 |
|
| 2013 |
Bix GJ. Perlecan domain V therapy for stroke: a beacon of hope? Acs Chemical Neuroscience. 4: 370-4. PMID 23509972 DOI: 10.1021/Cn300197Y |
0.516 |
|
| 2013 |
Kahle MP, Bix GJ. Neuronal restoration following ischemic stroke: influences, barriers, and therapeutic potential. Neurorehabilitation and Neural Repair. 27: 469-78. PMID 23392917 DOI: 10.1177/1545968312474119 |
0.432 |
|
| 2013 |
Bix G, Fu J, Gonzalez EM, Macro L, Barker A, Campbell S, Zutter MM, Santoro SA, Kim JK, Höök M, Reed CC, Iozzo RV. Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through α2β1 integrin The Journal of Cell Biology. 201: 641-641. DOI: 10.1083/Jcb.20040115004252013C |
0.32 |
|
| 2012 |
Kahle MP, Bix GJ. Successfully Climbing the "STAIRs": Surmounting Failed Translation of Experimental Ischemic Stroke Treatments. Stroke Research and Treatment. 2012: 374098. PMID 23326759 DOI: 10.1155/2012/374098 |
0.47 |
|
| 2012 |
Clarke DN, Al Ahmad A, Lee B, Parham C, Auckland L, Fertala A, Kahle M, Shaw CS, Roberts J, Bix GJ. Perlecan Domain V induces VEGf secretion in brain endothelial cells through integrin α5β1 and ERK-dependent signaling pathways. Plos One. 7: e45257. PMID 23028886 DOI: 10.1371/Journal.Pone.0045257 |
0.429 |
|
| 2012 |
Roberts J, Kahle MP, Bix GJ. Perlecan and the blood-brain barrier: beneficial proteolysis? Frontiers in Pharmacology. 3: 155. PMID 22936915 DOI: 10.3389/Fphar.2012.00155 |
0.509 |
|
| 2012 |
Kahle MP, Lee B, Pourmohamad T, Cunningham A, Su H, Kim H, Chen Y, McCulloch CE, Barbaro NM, Lawton MT, Young WL, Bix GJ. Perlecan domain V is upregulated in human brain arteriovenous malformation and could mediate the vascular endothelial growth factor effect in lesional tissue. Neuroreport. 23: 627-30. PMID 22643235 DOI: 10.1097/Wnr.0B013E3283554C5C |
0.391 |
|
| 2012 |
Saini MG, Bix GJ. Oxygen-glucose deprivation (OGD) and interleukin-1 (IL-1) differentially modulate cathepsin B/L mediated generation of neuroprotective perlecan LG3 by neurons. Brain Research. 1438: 65-74. PMID 22244880 DOI: 10.1016/J.Brainres.2011.12.027 |
0.342 |
|
| 2012 |
Wright S, Parham C, Lee B, Clarke D, Auckland L, Johnston J, Lawrence AL, Dickeson SK, Santoro SA, Griswold-Prenner I, Bix G. Perlecan domain V inhibits α2 integrin-mediated amyloid-β neurotoxicity. Neurobiology of Aging. 33: 1379-88. PMID 21126803 DOI: 10.1016/J.Neurobiolaging.2010.10.018 |
0.326 |
|
| 2012 |
Bix G. Perlecan domain V promotes neuronal regeneration of stroked brain tissue Journal of Stem Cell Research & Therapy. 1. DOI: 10.4172/2157-7633.S1.002 |
0.368 |
|
| 2012 |
Lee B, Clarke D, Al Ahmad A, Kahle M, Parham C, Auckland L, Shaw C, Fidanboylu M, Orr AW, Ogunshola O, Fertala A, Thomas SA, Bix GJ. Perlecan domain V is neuroprotective and proangiogenic following ischemic stroke in rodents (Journal of Clinical Investigation (2011) 121, 8 (3005-3023) DOI: 10.1172/JCI46358) Journal of Clinical Investigation. 122: 777. DOI: 10.1172/JCI61899 |
0.38 |
|
| 2011 |
Saini MG, Pinteaux E, Lee B, Bix GJ. Oxygen-glucose deprivation and interleukin-1α trigger the release of perlecan LG3 by cells of neurovascular unit. Journal of Neurochemistry. 119: 760-71. PMID 21919908 DOI: 10.1111/J.1471-4159.2011.07484.X |
0.354 |
|
| 2011 |
Al-Ahmad AJ, Lee B, Saini M, Bix GJ. Perlecan domain V modulates astrogliosis in vitro and after focal cerebral ischemia through multiple receptors and increased nerve growth factor release. Glia. 59: 1822-40. PMID 21850672 DOI: 10.1002/Glia.21227 |
0.694 |
|
| 2011 |
Lee B, Clarke D, Al Ahmad A, Kahle M, Parham C, Auckland L, Shaw C, Fidanboylu M, Orr AW, Ogunshola O, Fertala A, Thomas SA, Bix GJ. Perlecan domain V is neuroprotective and proangiogenic following ischemic stroke in rodents. The Journal of Clinical Investigation. 121: 3005-23. PMID 21747167 DOI: 10.1172/Jci46358 |
0.703 |
|
| 2010 |
Al Ahmad A, Lee B, Stack J, Parham C, Campbell J, Clarke D, Fertala A, Bix GJ. Endostatin binds nerve growth factor and thereby inhibits neurite outgrowth and neuronal migration in-vitro. Brain Research. 1360: 28-39. PMID 20846515 DOI: 10.1016/J.Brainres.2010.09.023 |
0.332 |
|
| 2010 |
Clarke DN, Bix GJ. Proteolytic extracellular matrix fragments following ischemic stroke: New insights to potential therapeutic targets Open Drug Discovery Journal. 2: 168-173. |
0.447 |
|
| 2009 |
Bix GJ. Perlecan Domain V Inhibits Brain Endothelial Cell Abeta Toxicity in Vitro Alzheimers & Dementia. 5. DOI: 10.1016/J.Jalz.2009.07.098 |
0.344 |
|
| 2005 |
Bix G, Iozzo RV. Matrix revolutions: "tails" of basement-membrane components with angiostatic functions. Trends in Cell Biology. 15: 52-60. PMID 15653078 DOI: 10.1016/J.Tcb.2004.11.008 |
0.339 |
|
| 1998 |
Bix GJ, Clark GD. Platelet-activating factor receptor stimulation disrupts neuronal migration in vitro Journal of Neuroscience. 18: 307-318. PMID 9412509 DOI: 10.1523/Jneurosci.18-01-00307.1998 |
0.32 |
|
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