Brenton D. Hoffman, Ph.D. - Publications

Affiliations: 
2007 University of Pennsylvania, Philadelphia, PA, United States 
Area:
General Biophysics, Chemical Engineering

40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Shoyer TC, Collins KL, Ham TR, Blanchard AT, Malavade JN, Johns BA, West JL, Hoffman BD. Detection of fluorescent protein mechanical switching in cellulo. Cell Reports Methods. 100815. PMID 38986612 DOI: 10.1016/j.crmeth.2024.100815  0.352
2024 Shoyer TC, Collins KL, Ham TR, Blanchard AT, Malavade JN, West JL, Hoffman BD. Detection of Fluorescent Protein Mechanical Switching in Cellulo. Biorxiv : the Preprint Server For Biology. PMID 38260589 DOI: 10.1101/2024.01.10.575065  0.341
2023 Shoyer TC, Gates EM, Cabe JI, Urs AN, Conway DE, Hoffman BD. Coupling during collective cell migration is controlled by a vinculin mechanochemical switch. Proceedings of the National Academy of Sciences of the United States of America. 120: e2316456120. PMID 38055737 DOI: 10.1073/pnas.2316456120  0.333
2023 Shoyer TC, Gates EM, Cabe JI, Conway DE, Hoffman BD. Coupling During Collective Cell Migration is Controlled by a Vinculin Mechanochemical Switch. Biorxiv : the Preprint Server For Biology. PMID 36711698 DOI: 10.1101/2023.01.13.523997  0.365
2020 Keeley DP, Hastie E, Jayadev R, Kelley LC, Chi Q, Payne SG, Jeger JL, Hoffman BD, Sherwood DR. Comprehensive Endogenous Tagging of Basement Membrane Components Reveals Dynamic Movement within the Matrix Scaffolding. Developmental Cell. PMID 32585132 DOI: 10.1016/J.Devcel.2020.05.022  0.304
2019 Ham TR, Collins KL, Hoffman BD. Molecular Tension Sensors: Moving Beyond Force. Current Opinion in Biomedical Engineering. 12: 83-94. PMID 32864525 DOI: 10.1016/J.Cobme.2019.10.003  0.36
2019 Mosier JA, Rahman-Zaman A, Zanotelli MR, VanderBurgh JA, Bordeleau F, Hoffman BD, Reinhart-King CA. Extent of Cell Confinement in Microtracks Affects Speed and Results in Differential Matrix Strains. Biophysical Journal. PMID 31623884 DOI: 10.1016/J.Bpj.2019.09.024  0.417
2019 Sengupta S, Rothenberg KE, Li H, Hoffman BD, Bursac N. Altering integrin engagement regulates membrane localization of K2.1 channels. Journal of Cell Science. PMID 31391240 DOI: 10.1242/Jcs.225383  0.324
2019 Gilchrist CL, Leddy HA, Kaye L, Case ND, Rothenberg KE, Little D, Liedtke W, Hoffman BD, Guilak F. TRPV4-mediated calcium signaling in mesenchymal stem cells regulates aligned collagen matrix formation and vinculin tension. Proceedings of the National Academy of Sciences of the United States of America. PMID 30674675 DOI: 10.1073/Pnas.1811095116  0.384
2018 Gates EM, LaCroix AS, Rothenberg KE, Hoffman BD. Improving Quality, Reproducibility, and Usability of FRET-Based Tension Sensors. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 30523675 DOI: 10.1002/Cyto.A.23688  0.321
2018 Rothenberg KE, Puranam I, Hoffman BD. Measurement of Force-Sensitive Protein Dynamics in Living Cells Using a Combination of Fluorescent Techniques. Journal of Visualized Experiments : Jove. PMID 30451225 DOI: 10.3791/58619  0.435
2018 LaCroix AS, Lynch AD, Berginski ME, Hoffman BD. Tunable molecular tension sensors reveal extension-based control of vinculin loading. Elife. 7. PMID 30024378 DOI: 10.7554/Elife.33927  0.312
2018 Rothenberg KE, Scott DW, Christoforou N, Hoffman BD. Vinculin Force-Sensitive Dynamics at Focal Adhesions Enable Effective Directed Cell Migration. Biophysical Journal. 114: 1680-1694. PMID 29642037 DOI: 10.1016/J.Bpj.2018.02.019  0.477
2018 Graham DM, Andersen T, Sharek L, Uzer G, Rothenberg K, Hoffman BD, Rubin J, Balland M, Bear JE, Burridge K. Enucleated cells reveal differential roles of the nucleus in cell migration, polarity, and mechanotransduction. The Journal of Cell Biology. PMID 29351995 DOI: 10.1083/Jcb.201706097  0.395
2017 Shams H, Hoffman BD, Mofrad M. The ?stressful? life of adhesion molecules: On the molecular mechanosensitivity of adhesomes. Journal of Biomechanical Engineering. PMID 29272321 DOI: 10.1115/1.4038812  0.431
2017 Pomeroy JE, Nguyen HX, Hoffman BD, Bursac N. Genetically Encoded Photoactuators and Photosensors for Characterization and Manipulation of Pluripotent Stem Cells. Theranostics. 7: 3539-3558. PMID 28912894 DOI: 10.7150/Thno.20593  0.349
2017 Mao M, Wang L, Chang CC, Rothenberg KE, Huang J, Wang Y, Hoffman BD, Liton PB, Yuan F. Involvement of a Rac1-Dependent Macropinocytosis Pathway in Plasmid DNA Delivery by Electrotransfection. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28129959 DOI: 10.1016/J.Ymthe.2016.12.009  0.352
2015 Hoffman BD, Yap AS. Towards a Dynamic Understanding of Cadherin-Based Mechanobiology. Trends in Cell Biology. PMID 26519989 DOI: 10.1016/J.Tcb.2015.09.008  0.476
2015 LaCroix AS, Rothenberg KE, Hoffman BD. Molecular-Scale Tools for Studying Mechanotransduction. Annual Review of Biomedical Engineering. 17: 287-316. PMID 26421895 DOI: 10.1146/Annurev-Bioeng-071114-040531  0.402
2015 LaCroix AS, Rothenberg KE, Berginski ME, Urs AN, Hoffman BD. Construction, imaging, and analysis of FRET-based tension sensors in living cells. Methods in Cell Biology. 125: 161-86. PMID 25640429 DOI: 10.1016/Bs.Mcb.2014.10.033  0.334
2015 Rothenberg KE, Neibart SS, LaCroix AS, Hoffman BD. Controlling Cell Geometry Affects the Spatial Distribution of Load Across Vinculin Cellular and Molecular Bioengineering. 8: 364-382. DOI: 10.1007/S12195-015-0404-9  0.451
2014 Hoffman BD. The detection and role of molecular tension in focal adhesion dynamics. Progress in Molecular Biology and Translational Science. 126: 3-24. PMID 25081612 DOI: 10.1016/B978-0-12-394624-9.00001-4  0.468
2014 Leerberg JM, Gomez GA, Verma S, Moussa EJ, Wu SK, Priya R, Hoffman BD, Grashoff C, Schwartz MA, Yap AS. Tension-sensitive actin assembly supports contractility at the epithelial zonula adherens. Current Biology : Cb. 24: 1689-99. PMID 25065757 DOI: 10.1016/J.Cub.2014.06.028  0.327
2014 Hwang PY, Chen J, Jing L, Hoffman BD, Setton LA. The role of extracellular matrix elasticity and composition in regulating the nucleus pulposus cell phenotype in the intervertebral disc: a narrative review. Journal of Biomechanical Engineering. 136: 021010. PMID 24390195 DOI: 10.1115/1.4026360  0.342
2012 Schnaar R, Paulson JC, Macauley MS, Nycholat C, Pfrengle F, Rademacher C, Mahan A, Dionne K, Suscovich T, Alter G, Katoh T, Kiwamoto T, Brummet M, Bochner B, Tiemeyer M, ... ... Hoffman B, et al. Program and abstracts for the 2012 Joint Meeting of the Society for Glycobiology & American Society for Matrix Biology Glycobiology. 22: 1518-1650. DOI: 10.1093/Glycob/Cws127  0.332
2011 Hoffman BD, Grashoff C, Schwartz MA. Dynamic molecular processes mediate cellular mechanotransduction. Nature. 475: 316-23. PMID 21776077 DOI: 10.1038/Nature10316  0.409
2011 Goguen BN, Hoffman BD, Sellers JR, Schwartz MA, Imperiali B. Light-triggered myosin activation for probing dynamic cellular processes. Angewandte Chemie (International Ed. in English). 50: 5667-70. PMID 21542072 DOI: 10.1002/Anie.201100674  0.353
2010 Grashoff C, Hoffman BD, Brenner MD, Zhou R, Parsons M, Yang MT, McLean MA, Sligar SG, Chen CS, Ha T, Schwartz MA. Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics. Nature. 466: 263-6. PMID 20613844 DOI: 10.1038/Nature09198  0.423
2009 Hoffman BD, Crocker JC. Cell mechanics: dissecting the physical responses of cells to force. Annual Review of Biomedical Engineering. 11: 259-88. PMID 19400709 DOI: 10.1146/Annurev.Bioeng.10.061807.160511  0.633
2007 Hoffman BD, Massiera G, Crocker JC. Fragility and mechanosensing in a thermalized cytoskeleton model with forced protein unfolding. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 76: 051906. PMID 18233686 DOI: 10.1103/Physreve.76.051906  0.581
2007 Crocker JC, Hoffman BD. Multiple-particle tracking and two-point microrheology in cells. Methods in Cell Biology. 83: 141-78. PMID 17613308 DOI: 10.1016/S0091-679X(07)83007-X  0.598
2006 Van Citters KM, Hoffman BD, Massiera G, Crocker JC. The role of F-actin and myosin in epithelial cell rheology. Biophysical Journal. 91: 3946-56. PMID 16950850 DOI: 10.1529/Biophysj.106.091264  0.626
2006 Hoffman BD, Massiera G, Van Citters KM, Crocker JC. The consensus mechanics of cultured mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 10259-64. PMID 16793927 DOI: 10.1073/Pnas.0510348103  0.615
2006 Byfield FJ, Hoffman BD, Romanenko VG, Fang Y, Crocker JC, Levitan I. Evidence for the role of cell stiffness in modulation of volume-regulated anion channels. Acta Physiologica (Oxford, England). 187: 285-94. PMID 16734765 DOI: 10.1111/J.1748-1716.2006.01555.X  0.562
2006 Liu J, Gardel ML, Kroy K, Frey E, Hoffman BD, Crocker JC, Bausch AR, Weitz DA. Microrheology probes length scale dependent rheology. Physical Review Letters. 96: 118104. PMID 16605878 DOI: 10.1103/Physrevlett.96.118104  0.54
2006 Crocker J, Hoffman B, Massiera G. Deformability and mechano-sensing in a cytoskeleton model with forced protein unfolding Journal of Biomechanics. 39: S240-S241. DOI: 10.1016/S0021-9290(06)83906-0  0.529
2006 Crocker J, Massiera G, Hoffman B. The consensus mechanical response of cells and the role of dynamic protein cross-links Journal of Biomechanics. 39: S237. DOI: 10.1016/S0021-9290(06)83887-X  0.563
2005 Hoffman BD, Massiera G, Miranda K, Crocker J. Polymer physics of the cytoskeleton Aiche Annual Meeting, Conference Proceedings. 181.  0.369
2005 Miranda K, Hoffman BD, Massiera G, Crocker J. Determining the effect of cytoskeleton disruption on cell rheology Aiche Annual Meeting, Conference Proceedings. 5021.  0.341
2003 Lau AW, Hoffman BD, Davies A, Crocker JC, Lubensky TC. Microrheology, stress fluctuations, and active behavior of living cells. Physical Review Letters. 91: 198101. PMID 14611619 DOI: 10.1103/Physrevlett.91.198101  0.56
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