Rakesh K. Jain - Publications

Affiliations: 
Engineering and Applied Sciences Harvard University, Cambridge, MA, United States 
Area:
Biomedical Engineering

176 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Martin JD, Cabral H, Stylianopoulos T, Jain RK. Improving cancer immunotherapy using nanomedicines: progress, opportunities and challenges. Nature Reviews. Clinical Oncology. PMID 32034288 DOI: 10.1038/s41571-019-0308-z  0.36
2020 Mpekris F, Voutouri C, Baish JW, Duda DG, Munn LL, Stylianopoulos T, Jain RK. Combining microenvironment normalization strategies to improve cancer immunotherapy. Proceedings of the National Academy of Sciences of the United States of America. PMID 32015113 DOI: 10.1073/pnas.1919764117  0.48
2019 Munn LL, Jain RK. Vascular regulation of antitumor immunity. Science (New York, N.Y.). 365: 544-545. PMID 31395771 DOI: 10.1126/science.aaw7875  0.48
2019 Murphy JE, Wo JY, Ryan DP, Clark JW, Jiang W, Yeap BY, Drapek LC, Ly L, Baglini CV, Blaszkowsky LS, Ferrone CR, Parikh AR, Weekes CD, Nipp RD, Kwak EL, ... ... Jain RK, et al. Total Neoadjuvant Therapy With FOLFIRINOX in Combination With Losartan Followed by Chemoradiotherapy for Locally Advanced Pancreatic Cancer: A Phase 2 Clinical Trial. Jama Oncology. PMID 31145418 DOI: 10.1001/jamaoncol.2019.0892  0.64
2019 Chauhan VP, Chen IX, Tong R, Ng MR, Martin JD, Naxerova K, Wu MW, Huang P, Boucher Y, Kohane DS, Langer R, Jain RK. Reprogramming the microenvironment with tumor-selective angiotensin blockers enhances cancer immunotherapy. Proceedings of the National Academy of Sciences of the United States of America. PMID 31040208 DOI: 10.1073/pnas.1819889116  0.88
2019 Seano G, Nia HT, Emblem KE, Datta M, Ren J, Krishnan S, Kloepper J, Pinho MC, Ho WW, Ghosh M, Askoxylakis V, Ferraro GB, Riedemann L, Gerstner ER, Batchelor TT, ... ... Jain RK, et al. Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium. Nature Biomedical Engineering. 3: 230-245. PMID 30948807 DOI: 10.1038/s41551-018-0334-7  0.6
2019 Cleary JM, Horick NK, McCleary NJ, Abrams TA, Yurgelun MB, Azzoli CG, Rubinson DA, Brooks GA, Chan JA, Blaszkowsky LS, Clark JW, Goyal L, Meyerhardt JA, Ng K, Schrag D, ... ... Jain RK, et al. FOLFOX plus ziv-aflibercept or placebo in first-line metastatic esophagogastric adenocarcinoma: A double-blind, randomized, multicenter phase 2 trial. Cancer. PMID 30913304 DOI: 10.1002/cncr.32029  0.64
2019 Chen IX, Chauhan VP, Posada J, Ng MR, Wu MW, Adstamongkonkul P, Huang P, Lindeman N, Langer R, Jain RK. Blocking CXCR4 alleviates desmoplasia, increases T-lymphocyte infiltration, and improves immunotherapy in metastatic breast cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 30700545 DOI: 10.1073/pnas.1815515116  0.88
2019 Voutouri C, Kirkpatrick ND, Chung E, Mpekris F, Baish JW, Munn LL, Fukumura D, Stylianopoulos T, Jain RK. Experimental and computational analyses reveal dynamics of tumor vessel cooption and optimal treatment strategies. Proceedings of the National Academy of Sciences of the United States of America. PMID 30700544 DOI: 10.1073/pnas.1818322116  0.48
2019 Zhao Y, Cao J, Melamed A, Worley M, Gockley A, Jones D, Nia HT, Zhang Y, Stylianopoulos T, Kumar AS, Mpekris F, Datta M, Sun Y, Wu L, Gao X, ... ... Jain RK, et al. Losartan treatment enhances chemotherapy efficacy and reduces ascites in ovarian cancer models by normalizing the tumor stroma. Proceedings of the National Academy of Sciences of the United States of America. PMID 30659155 DOI: 10.1073/pnas.1818357116  0.6
2019 Nia HT, Munn LL, Jain RK. Mapping physical tumor microenvironment and drug delivery. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30630829 DOI: 10.1158/1078-0432.CCR-18-3724  0.6
2018 Liao S, Bouta EM, Morris LM, Jones D, Jain RK, Padera TP. Inducible Nitric Oxide Synthase and CD11bGr1 Cells Impair Lymphatic Contraction of Tumor-Draining Lymphatic Vessels. Lymphatic Research and Biology. PMID 30358484 DOI: 10.1089/lrb.2018.0013  0.4
2018 Nowak-Sliwinska P, Alitalo K, Allen E, Anisimov A, Aplin AC, Auerbach R, Augustin HG, Bates DO, van Beijnum JR, Bender RHF, Bergers G, Bikfalvi A, Bischoff J, Böck BC, Brooks PC, ... ... Jain RK, et al. Consensus guidelines for the use and interpretation of angiogenesis assays. Angiogenesis. PMID 29766399 DOI: 10.1007/s10456-018-9613-x  0.48
2018 Nia HT, Datta M, Seano G, Huang P, Munn LL, Jain RK. Quantifying solid stress and elastic energy from excised or in situ tumors. Nature Protocols. 13: 1091-1105. PMID 29674756 DOI: 10.1038/nprot.2018.020  0.6
2018 Stylianopoulos T, Munn LL, Jain RK. Reengineering the Physical Microenvironment of Tumors to Improve Drug Delivery and Efficacy: From Mathematical Modeling to Bench to Bedside. Trends in Cancer. 4: 292-319. PMID 29606314 DOI: 10.1016/j.trecan.2018.02.005  0.48
2018 Stylianopoulos T, Munn LL, Jain RK. Reengineering the Tumor Vasculature: Improving Drug Delivery and Efficacy. Trends in Cancer. 4: 258-259. PMID 29606306 DOI: 10.1016/j.trecan.2018.02.010  0.48
2018 Incio J, Ligibel JA, McManus DT, Suboj P, Jung K, Kawaguchi K, Pinter M, Babykutty S, Chin SM, Vardam TD, Huang Y, Rahbari NN, Roberge S, Wang D, Gomes-Santos IL, ... ... Jain RK, et al. Obesity promotes resistance to anti-VEGF therapy in breast cancer by up-regulating IL-6 and potentially FGF-2. Science Translational Medicine. 10. PMID 29540614 DOI: 10.1126/scitranslmed.aag0945  0.64
2017 Jung K, Heishi T, Incio J, Huang Y, Beech EY, Pinter M, Ho WW, Kawaguchi K, Rahbari NN, Chung E, Kim JK, Clark JW, Willett CG, Yun SH, Luster AD, ... ... Jain RK, et al. Targeting CXCR4-dependent immunosuppressive Ly6C(low) monocytes improves antiangiogenic therapy in colorectal cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 28900008 DOI: 10.1073/pnas.1710754114  0.4
2017 Jung K, Heishi T, Khan OF, Kowalski PS, Incio J, Rahbari NN, Chung E, Clark JW, Willett CG, Luster AD, Yun SH, Langer R, Anderson DG, Padera TP, Jain RK, et al. Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy. The Journal of Clinical Investigation. PMID 28691930 DOI: 10.1172/JCI93182  0.4
2017 Naxerova K, Reiter JG, Brachtel E, Lennerz JK, van de Wetering M, Rowan A, Cai T, Clevers H, Swanton C, Nowak MA, Elledge SJ, Jain RK. Origins of lymphatic and distant metastases in human colorectal cancer. Science (New York, N.Y.). 357: 55-60. PMID 28684519 DOI: 10.1126/science.aai8515  0.8
2017 Liu H, Naxerova K, Pinter M, Incio J, Lee H, Shigeta K, Ho WW, Crain JA, Jacobson A, Michelakos T, Dias-Santos D, Zanconato A, Hong TS, Clark JW, Murphy JE, ... ... Jain RK, et al. Use of Angiotensin System Inhibitors is Associated with Immune Activation and Longer Survival in Non-Metastatic Pancreatic Ductal Adenocarcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28600474 DOI: 10.1158/1078-0432.CCR-17-0256  0.8
2017 Kodack DP, Askoxylakis V, Ferraro GB, Sheng Q, Badeaux M, Goel S, Qi X, Shankaraiah R, Cao ZA, Ramjiawan RR, Bezwada D, Patel B, Song Y, Costa C, Naxerova K, ... ... Jain RK, et al. The brain microenvironment mediates resistance in luminal breast cancer to PI3K inhibition through HER3 activation. Science Translational Medicine. 9. PMID 28539475 DOI: 10.1126/scitranslmed.aal4682  0.8
2017 Mpekris F, Baish JW, Stylianopoulos T, Jain RK. Role of vascular normalization in benefit from metronomic chemotherapy. Proceedings of the National Academy of Sciences of the United States of America. PMID 28174262 DOI: 10.1073/pnas.1700340114  0.36
2017 Gupta N, Badeaux M, Liu Y, Naxerova K, Sgroi D, Munn LL, Jain RK, Garkavtsev I. Stress granule-associated protein G3BP2 regulates breast tumor initiation. Proceedings of the National Academy of Sciences of the United States of America. PMID 28096337 DOI: 10.1073/pnas.1525387114  0.8
2016 Nia HT, Liu H, Seano G, Datta M, Jones D, Rahbari N, Incio J, Chauhan VP, Jung K, Martin JD, Askoxylakis V, Padera TP, Fukumura D, Boucher Y, Hornicek FJ, ... ... Jain RK, et al. Solid stress and elastic energy as measures of tumour mechanopathology. Nature Biomedical Engineering. 1. PMID 28966873 DOI: 10.1038/s41551-016-0004  0.88
2016 Martin JD, Fukumura D, Duda DG, Boucher Y, Jain RK. Corrigendum: Reengineering the Tumor Microenvironment to Alleviate Hypoxia and Overcome Cancer Heterogeneity. Cold Spring Harbor Perspectives in Medicine. 6. PMID 27908927 DOI: 10.1101/cshperspect.a031195  0.64
2016 Hajjarian Z, Nia HT, Ahn S, Grodzinsky AJ, Jain RK, Nadkarni SK. Laser Speckle Rheology for evaluating the viscoelastic properties of hydrogel scaffolds. Scientific Reports. 6: 37949. PMID 27905494 DOI: 10.1038/srep37949  0.6
2016 Kumar V, Boucher Y, Liu H, Ferreira D, Hooker J, Catana C, Hoover AJ, Ritter T, Jain RK, Guimaraes AR. Noninvasive Assessment of Losartan-Induced Increase in Functional Microvasculature and Drug Delivery in Pancreatic Ductal Adenocarcinoma. Translational Oncology. 9: 431-437. PMID 27751347 DOI: 10.1016/j.tranon.2016.07.004  0.64
2016 Rahbari NN, Kedrin D, Incio J, Liu H, Ho WW, Nia HT, Edrich CM, Jung K, Daubriac J, Chen I, Heishi T, Martin JD, Huang Y, Maimon N, Reissfelder C, ... ... Jain RK, et al. Anti-VEGF therapy induces ECM remodeling and mechanical barriers to therapy in colorectal cancer liver metastases. Science Translational Medicine. 8: 360ra135. PMID 27733559 DOI: 10.1126/scitranslmed.aaf5219  0.88
2016 Martin JD, Fukumura D, Duda DG, Boucher Y, Jain RK. Reengineering the Tumor Microenvironment to Alleviate Hypoxia and Overcome Cancer Heterogeneity. Cold Spring Harbor Perspectives in Medicine. PMID 27663981 DOI: 10.1101/cshperspect.a027094  0.64
2016 Incio J, Liu H, Suboj P, Chin SM, Chen IX, Pinter M, Ng MR, Nia HT, Grahovac J, Kao S, Babykutty S, Huang Y, Jung K, Rahbari NN, Han X, ... ... Jain RK, et al. Obesity-induced inflammation and desmoplasia promote pancreatic cancer progression and resistance to chemotherapy. Cancer Discovery. PMID 27246539 DOI: 10.1158/2159-8290.CD-15-1177  0.88
2016 Kloepper J, Riedemann L, Amoozgar Z, Seano G, Susek K, Yu V, Dalvie N, Amelung RL, Datta M, Song JW, Askoxylakis V, Taylor JW, Lu-Emerson C, Batista A, Kirkpatrick ND, ... ... Jain RK, et al. Ang-2/VEGF bispecific antibody reprograms macrophages and resident microglia to anti-tumor phenotype and prolongs glioblastoma survival. Proceedings of the National Academy of Sciences of the United States of America. PMID 27044098 DOI: 10.1073/pnas.1525360113  0.88
2016 Peterson TE, Kirkpatrick ND, Huang Y, Farrar CT, Marijt KA, Kloepper J, Datta M, Amoozgar Z, Seano G, Jung K, Kamoun WS, Vardam T, Snuderl M, Goveia J, Chatterjee S, ... ... Jain RK, et al. Dual inhibition of Ang-2 and VEGF receptors normalizes tumor vasculature and prolongs survival in glioblastoma by altering macrophages. Proceedings of the National Academy of Sciences of the United States of America. PMID 27044097 DOI: 10.1073/pnas.1525349113  0.88
2016 Incio J, Tam J, Rahbari NN, Suboj P, McManus DT, Chin SM, Vardam T, Batista A, Babykutty S, Jung K, Khachatryan A, Hato T, Ligibel JA, Krop I, Puchner SB, ... ... Jain RK, et al. PlGF/VEGFR-1 signaling promotes macrophage polarization and accelerated tumor progression in obesity. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26861455 DOI: 10.1158/1078-0432.CCR-15-1839  0.88
2016 Askoxylakis V, Ferraro GB, Kodack DP, Badeaux M, Shankaraiah RC, Seano G, Kloepper J, Vardam T, Martin JD, Naxerova K, Bezwada D, Qi X, Selig MK, Brachtel E, Duda DG, ... ... Jain RK, et al. Preclinical Efficacy of Ado-trastuzumab Emtansine in the Brain Microenvironment. Journal of the National Cancer Institute. 108. PMID 26547932 DOI: 10.1093/jnci/djv313  0.88
2015 Singhal PK, Sassi S, Lan L, Au P, Halvorsen SC, Fukumura D, Jain RK, Seed B. Mouse embryonic fibroblasts exhibit extensive developmental and phenotypic diversity. Proceedings of the National Academy of Sciences of the United States of America. PMID 26699463 DOI: 10.1073/pnas.1522401112  0.88
2015 Incio J, Suboj P, Chin SM, Vardam-Kaur T, Liu H, Hato T, Babykutty S, Chen I, Deshpande V, Jain RK, Fukumura D. Metformin Reduces Desmoplasia in Pancreatic Cancer by Reprogramming Stellate Cells and Tumor-Associated Macrophages. Plos One. 10: e0141392. PMID 26641266 DOI: 10.1371/journal.pone.0141392  0.88
2015 Tolaney SM, Boucher Y, Duda DG, Martin JD, Seano G, Ancukiewicz M, Barry WT, Goel S, Lahdenrata J, Isakoff SJ, Yeh ED, Jain SR, Golshan M, Brock J, Snuderl M, ... ... Jain RK, et al. Role of vascular density and normalization in response to neoadjuvant bevacizumab and chemotherapy in breast cancer patients. Proceedings of the National Academy of Sciences of the United States of America. 112: 14325-14330. PMID 26578779 DOI: 10.1073/pnas.1518808112  0.88
2015 Samuel R, Duda DG, Fukumura D, Jain RK. Vascular diseases await translation of blood vessels engineered from stem cells. Science Translational Medicine. 7: 309rv6. PMID 26468328 DOI: 10.1126/scitranslmed.aaa1805  0.88
2015 Stylianopoulos T, Jain RK. Design considerations for nanotherapeutics in oncology. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 26282377 DOI: 10.1016/j.nano.2015.07.015  0.88
2015 Datta M, Via LE, Chen W, Baish JW, Xu L, Barry CE, Jain RK. Mathematical Model of Oxygen Transport in Tuberculosis Granulomas. Annals of Biomedical Engineering. PMID 26253038 DOI: 10.1007/s10439-015-1415-3  0.88
2015 Batista A, Riedemann L, Vardam T, Jain RK. Targeting the Tumor Microenvironment to Enhance Pediatric Brain Cancer Treatment. Cancer Journal (Sudbury, Mass.). 21: 307-13. PMID 26222083 DOI: 10.1097/PPO.0000000000000125  0.88
2015 Jain RK, Fukumura D, Duda DG. From the Guest Editors: Role of Tumor Microenvironment in Tumor Progression and Treatment Response: A 30 Years' Journey. Cancer Journal (Sudbury, Mass.). 21: 235-6. PMID 26222072 DOI: 10.1097/PPO.0000000000000136  0.88
2015 Lemon CM, Karnas E, Han X, Bruns OT, Kempa TJ, Fukumura D, Bawendi MG, Jain RK, Duda DG, Nocera DG. Micelle-Encapsulated Quantum Dot-Porphyrin Assemblies as in Vivo Two-Photon Oxygen Sensors. Journal of the American Chemical Society. PMID 26149349 DOI: 10.1021/jacs.5b04765  0.88
2015 Duda DG, Heist RS, Sahani DV, Stylianopoulos T, Engelman JA, Jain RK. Reply to Ciccolini et al.: Using mathematical modeling to predict response to antiangiogenic therapy in cancer patients. Proceedings of the National Academy of Sciences of the United States of America. 112: E3454. PMID 26080434 DOI: 10.1073/pnas.1507225112  0.88
2015 Jeong HS, Jones D, Liao S, Wattson DA, Cui CH, Duda DG, Willett CG, Jain RK, Padera TP. Investigation of the Lack of Angiogenesis in the Formation of Lymph Node Metastases. Journal of the National Cancer Institute. 107. PMID 26063793 DOI: 10.1093/jnci/djv155  0.4
2015 Jain RK, Fukumura D, Duda DG. Lessons From 30 Years of Teaching About the Microenvironment of Tumors. Cancer Journal (Sudbury, Mass.). 21: 137. PMID 26049690 DOI: 10.1097/PPO.0000000000000119  0.88
2015 Lu-Emerson C, Duda DG, Emblem KE, Taylor JW, Gerstner ER, Loeffler JS, Batchelor TT, Jain RK. Lessons from anti-vascular endothelial growth factor and anti-vascular endothelial growth factor receptor trials in patients with glioblastoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 33: 1197-213. PMID 25713439 DOI: 10.1200/JCO.2014.55.9575  0.88
2015 Ager EI, Kozin SV, Kirkpatrick ND, Seano G, Kodack DP, Askoxylakis V, Huang Y, Goel S, Snuderl M, Muzikansky A, Finkelstein DM, Dransfield DT, Devy L, Boucher Y, Fukumura D, ... Jain RK, et al. Blockade of MMP14 activity in murine breast carcinomas: implications for macrophages, vessels, and radiotherapy. Journal of the National Cancer Institute. 107. PMID 25710962 DOI: 10.1093/jnci/djv017  0.88
2015 Stylianopoulos T, Economides EA, Baish JW, Fukumura D, Jain RK. Towards Optimal Design of Cancer Nanomedicines: Multi-stage Nanoparticles for the Treatment of Solid Tumors. Annals of Biomedical Engineering. PMID 25670323 DOI: 10.1007/s10439-015-1276-9  0.88
2015 Kodack DP, Askoxylakis V, Ferraro GB, Fukumura D, Jain RK. Emerging strategies for treating brain metastases from breast cancer. Cancer Cell. 27: 163-75. PMID 25670078 DOI: 10.1016/j.ccell.2015.01.001  0.88
2015 Datta M, Via LE, Kamoun WS, Liu C, Chen W, Seano G, Weiner DM, Schimel D, England K, Martin JD, Gao X, Xu L, Barry CE, Jain RK. Anti-vascular endothelial growth factor treatment normalizes tuberculosis granuloma vasculature and improves small molecule delivery. Proceedings of the National Academy of Sciences of the United States of America. 112: 1827-32. PMID 25624495 DOI: 10.1073/pnas.1424563112  0.88
2015 Heist RS, Duda DG, Sahani DV, Ancukiewicz M, Fidias P, Sequist LV, Temel JS, Shaw AT, Pennell NA, Neal JW, Gandhi L, Lynch TJ, Engelman JA, Jain RK. Improved tumor vascularization after anti-VEGF therapy with carboplatin and nab-paclitaxel associates with survival in lung cancer. Proceedings of the National Academy of Sciences of the United States of America. 112: 1547-52. PMID 25605928 DOI: 10.1073/pnas.1424024112  0.88
2015 Naxerova K, Jain RK. Using tumour phylogenetics to identify the roots of metastasis in humans. Nature Reviews. Clinical Oncology. 12: 258-72. PMID 25601447 DOI: 10.1038/nrclinonc.2014.238  0.88
2014 Jain RK. Antiangiogenesis strategies revisited: from starving tumors to alleviating hypoxia. Cancer Cell. 26: 605-22. PMID 25517747 DOI: 10.1016/j.ccell.2014.10.006  0.88
2014 Thunemann M, Schmidt K, de Wit C, Han X, Jain RK, Fukumura D, Feil R. Correlative intravital imaging of cGMP signals and vasodilation in mice. Frontiers in Physiology. 5: 394. PMID 25352809 DOI: 10.3389/fphys.2014.00394  0.88
2014 Chen O, Riedemann L, Etoc F, Herrmann H, Coppey M, Barch M, Farrar CT, Zhao J, Bruns OT, Wei H, Guo P, Cui J, Jensen R, Chen Y, Harris DK, ... ... Jain RK, et al. Magneto-fluorescent core-shell supernanoparticles. Nature Communications. 5: 5093. PMID 25298155 DOI: 10.1038/ncomms6093  0.88
2014 Jain RK, Netti PA. Letter to the editor regarding recent article by Wu et al. [J. Theor. Biol. 355 (2014) pp. 194-207]. Journal of Theoretical Biology. 363: 453. PMID 25219622 DOI: 10.1016/j.jtbi.2014.08.052  0.88
2014 Seano G, Chiaverina G, Gagliardi PA, di Blasio L, Puliafito A, Bouvard C, Sessa R, Tarone G, Sorokin L, Helley D, Jain RK, Serini G, Bussolino F, Primo L. Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis. Nature Cell Biology. 16: 931-41, 1-8. PMID 25218639 DOI: 10.1038/ncb3036  0.88
2014 Emblem KE, Farrar CT, Gerstner ER, Batchelor TT, Borra RJ, Rosen BR, Sorensen AG, Jain RK. Vessel caliber--a potential MRI biomarker of tumour response in clinical trials. Nature Reviews. Clinical Oncology. 11: 566-84. PMID 25113840 DOI: 10.1038/nrclinonc.2014.126  0.88
2014 Duda DG, Ancukiewicz M, Isakoff SJ, Krop IE, Jain RK. Seeds and soil: unraveling the role of local tumor stroma in distant metastasis. Journal of the National Cancer Institute. 106. PMID 25082335 DOI: 10.1093/jnci/dju187  0.88
2014 Chauhan VP, Boucher Y, Ferrone CR, Roberge S, Martin JD, Stylianopoulos T, Bardeesy N, DePinho RA, Padera TP, Munn LL, Jain RK. Compression of pancreatic tumor blood vessels by hyaluronan is caused by solid stress and not interstitial fluid pressure. Cancer Cell. 26: 14-5. PMID 25026209 DOI: 10.1016/j.ccr.2014.06.003  0.88
2014 Jain AK, Jain A, Garg NK, Agarwal A, Jain A, Jain SA, Tyagi RK, Jain RK, Agrawal H, Agrawal GP. Adapalene loaded solid lipid nanoparticles gel: an effective approach for acne treatment. Colloids and Surfaces. B, Biointerfaces. 121: 222-9. PMID 25016424 DOI: 10.1016/j.colsurfb.2014.05.041  0.88
2014 Jain RK, Martin JD, Stylianopoulos T. The role of mechanical forces in tumor growth and therapy. Annual Review of Biomedical Engineering. 16: 321-46. PMID 25014786 DOI: 10.1146/annurev-bioeng-071813-105259  0.88
2014 Hong TS, Ryan DP, Borger DR, Blaszkowsky LS, Yeap BY, Ancukiewicz M, Deshpande V, Shinagare S, Wo JY, Boucher Y, Wadlow RC, Kwak EL, Allen JN, Clark JW, Zhu AX, ... ... Jain RK, et al. A phase 1/2 and biomarker study of preoperative short course chemoradiation with proton beam therapy and capecitabine followed by early surgery for resectable pancreatic ductal adenocarcinoma. International Journal of Radiation Oncology, Biology, Physics. 89: 830-8. PMID 24867540 DOI: 10.1016/j.ijrobp.2014.03.034  0.88
2014 Naxerova K, Brachtel E, Salk JJ, Seese AM, Power K, Abbasi B, Snuderl M, Chiang S, Kasif S, Jain RK. Hypermutable DNA chronicles the evolution of human colon cancer. Proceedings of the National Academy of Sciences of the United States of America. 111: E1889-98. PMID 24753616 DOI: 10.1073/pnas.1400179111  0.88
2014 Jain RK. An indirect way to tame cancer. Scientific American. 310: 46-53. PMID 24640331 DOI: 10.1038/scientificamerican0214-46  0.88
2014 Pinho MC, Polaskova P, Kalpathy-Cramer J, Jennings D, Emblem KE, Jain RK, Rosen BR, Wen PY, Sorensen AG, Batchelor TT, Gerstner ER. Low incidence of pseudoprogression by imaging in newly diagnosed glioblastoma patients treated with cediranib in combination with chemoradiation. The Oncologist. 19: 75-81. PMID 24309981 DOI: 10.1634/theoncologist.2013-0101  0.88
2014 Chen Y, Huang Y, Reiberger T, Duyverman AM, Huang P, Samuel R, Hiddingh L, Roberge S, Koppel C, Lauwers GY, Zhu AX, Jain RK, Duda DG. Differential effects of sorafenib on liver versus tumor fibrosis mediated by stromal-derived factor 1 alpha/C-X-C receptor type 4 axis and myeloid differentiation antigen-positive myeloid cell infiltration in mice. Hepatology (Baltimore, Md.). 59: 1435-47. PMID 24242874 DOI: 10.1002/hep.26790  0.88
2014 Faber AC, Coffee EM, Costa C, Dastur A, Ebi H, Hata AN, Yeo AT, Edelman EJ, Song Y, Tam AT, Boisvert JL, Milano RJ, Roper J, Kodack DP, Jain RK, et al. mTOR inhibition specifically sensitizes colorectal cancers with KRAS or BRAF mutations to BCL-2/BCL-XL inhibition by suppressing MCL-1. Cancer Discovery. 4: 42-52. PMID 24163374 DOI: 10.1158/2159-8290.CD-13-0315  0.88
2014 Lemon CM, Curtin PN, Somers RC, Greytak AB, Lanning RM, Jain RK, Bawendi MG, Nocera DG. Metabolic tumor profiling with pH, oxygen, and glucose chemosensors on a quantum dot scaffold. Inorganic Chemistry. 53: 1900-15. PMID 24143874 DOI: 10.1021/ic401587r  0.88
2013 Huang Y, Stylianopoulos T, Duda DG, Fukumura D, Jain RK. Benefits of vascular normalization are dose and time dependent--letter. Cancer Research. 73: 7144-6. PMID 24265277 DOI: 10.1158/0008-5472.CAN-13-1989  0.88
2013 Batchelor TT, Gerstner ER, Emblem KE, Duda DG, Kalpathy-Cramer J, Snuderl M, Ancukiewicz M, Polaskova P, Pinho MC, Jennings D, Plotkin SR, Chi AS, Eichler AF, Dietrich J, Hochberg FH, ... ... Jain RK, et al. Improved tumor oxygenation and survival in glioblastoma patients who show increased blood perfusion after cediranib and chemoradiation. Proceedings of the National Academy of Sciences of the United States of America. 110: 19059-64. PMID 24190997 DOI: 10.1073/pnas.1318022110  0.88
2013 Stylianopoulos T, Jain RK. Combining two strategies to improve perfusion and drug delivery in solid tumors. Proceedings of the National Academy of Sciences of the United States of America. 110: 18632-7. PMID 24167277 DOI: 10.1073/pnas.1318415110  0.88
2013 Chauhan VP, Jain RK. Strategies for advancing cancer nanomedicine. Nature Materials. 12: 958-62. PMID 24150413 DOI: 10.1038/nmat3792  0.88
2013 Zhu AX, Finn RS, Mulcahy M, Gurtler J, Sun W, Schwartz JD, Dalal RP, Joshi A, Hozak RR, Xu Y, Ancukiewicz M, Jain RK, Nugent FW, Duda DG, Stuart K. A phase II and biomarker study of ramucirumab, a human monoclonal antibody targeting the VEGF receptor-2, as first-line monotherapy in patients with advanced hepatocellular cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 6614-23. PMID 24088738 DOI: 10.1158/1078-0432.CCR-13-1442  0.88
2013 Chauhan VP, Martin JD, Liu H, Lacorre DA, Jain SR, Kozin SV, Stylianopoulos T, Mousa AS, Han X, Adstamongkonkul P, Popovi? Z, Huang P, Bawendi MG, Boucher Y, Jain RK. Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels. Nature Communications. 4: 2516. PMID 24084631 DOI: 10.1038/ncomms3516  0.88
2013 Emblem KE, Mouridsen K, Bjornerud A, Farrar CT, Jennings D, Borra RJ, Wen PY, Ivy P, Batchelor TT, Rosen BR, Jain RK, Sorensen AG. Vessel architectural imaging identifies cancer patient responders to anti-angiogenic therapy. Nature Medicine. 19: 1178-83. PMID 23955713 DOI: 10.1038/nm.3289  0.88
2013 Batchelor TT, Mulholland P, Neyns B, Nabors LB, Campone M, Wick A, Mason W, Mikkelsen T, Phuphanich S, Ashby LS, Degroot J, Gattamaneni R, Cher L, Rosenthal M, Payer F, ... ... Jain RK, et al. Phase III randomized trial comparing the efficacy of cediranib as monotherapy, and in combination with lomustine, versus lomustine alone in patients with recurrent glioblastoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 3212-8. PMID 23940216 DOI: 10.1200/JCO.2012.47.2464  0.88
2013 Goel S, Gupta N, Walcott BP, Snuderl M, Kesler CT, Kirkpatrick ND, Heishi T, Huang Y, Martin JD, Ager E, Samuel R, Wang S, Yazbek J, Vakoc BJ, Peterson RT, ... ... Jain RK, et al. Effects of vascular-endothelial protein tyrosine phosphatase inhibition on breast cancer vasculature and metastatic progression. Journal of the National Cancer Institute. 105: 1188-201. PMID 23899555 DOI: 10.1093/jnci/djt164  0.88
2013 Samuel R, Daheron L, Liao S, Vardam T, Kamoun WS, Batista A, Buecker C, Schäfer R, Han X, Au P, Scadden DT, Duda DG, Fukumura D, Jain RK. Generation of functionally competent and durable engineered blood vessels from human induced pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 12774-9. PMID 23861493 DOI: 10.1073/pnas.1310675110  0.88
2013 Lu-Emerson C, Snuderl M, Kirkpatrick ND, Goveia J, Davidson C, Huang Y, Riedemann L, Taylor J, Ivy P, Duda DG, Ancukiewicz M, Plotkin SR, Chi AS, Gerstner ER, Eichler AF, ... ... Jain RK, et al. Increase in tumor-associated macrophages after antiangiogenic therapy is associated with poor survival among patients with recurrent glioblastoma. Neuro-Oncology. 15: 1079-87. PMID 23828240 DOI: 10.1093/neuonc/not082  0.88
2013 Jain RK, Munn LL, Fukumura D. Measuring interstitial diffusion, convection, and binding parameters in mouse tumors. Cold Spring Harbor Protocols. 2013: 678-80. PMID 23818670 DOI: 10.1101/pdb.prot075721  0.48
2013 Jain RK, Munn LL, Fukumura D. Measuring interstitial pH and pO2 in mouse tumors. Cold Spring Harbor Protocols. 2013: 675-7. PMID 23818669 DOI: 10.1101/pdb.prot075713  0.48
2013 Jain RK, Munn LL, Fukumura D. Measuring leukocyte-endothelial interactions in mice. Cold Spring Harbor Protocols. 2013: 561-3. PMID 23734020 DOI: 10.1101/pdb.prot075085  0.48
2013 Duda DG, Munn LL, Jain RK. Can we identify predictive biomarkers for antiangiogenic therapy of cancer using mathematical modeling? Journal of the National Cancer Institute. 105: 762-5. PMID 23670727 DOI: 10.1093/jnci/djt114  0.48
2013 Jain RK. Normalizing tumor microenvironment to treat cancer: bench to bedside to biomarkers. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 2205-18. PMID 23669226 DOI: 10.1200/JCO.2012.46.3653  0.88
2013 Jain RK, Munn LL, Fukumura D. Measuring vascular permeability in mice. Cold Spring Harbor Protocols. 2013: 444-6. PMID 23637370 DOI: 10.1101/pdb.prot074344  0.48
2013 Stylianopoulos T, Martin JD, Snuderl M, Mpekris F, Jain SR, Jain RK. Coevolution of solid stress and interstitial fluid pressure in tumors during progression: implications for vascular collapse. Cancer Research. 73: 3833-41. PMID 23633490 DOI: 10.1158/0008-5472.CAN-12-4521  0.88
2013 Jain RK, Munn LL, Fukumura D. Measuring angiogenesis and hemodynamics in mice. Cold Spring Harbor Protocols. 2013: 354-8. PMID 23547161 DOI: 10.1101/pdb.prot073916  0.48
2013 Chen O, Zhao J, Chauhan VP, Cui J, Wong C, Harris DK, Wei H, Han HS, Fukumura D, Jain RK, Bawendi MG. Compact high-quality CdSe-CdS core-shell nanocrystals with narrow emission linewidths and suppressed blinking. Nature Materials. 12: 445-51. PMID 23377294 DOI: 10.1038/nmat3539  0.88
2013 Zhu AX, Ancukiewicz M, Supko JG, Sahani DV, Blaszkowsky LS, Meyerhardt JA, Abrams TA, McCleary NJ, Bhargava P, Muzikansky A, Sheehan S, Regan E, Vasudev E, Knowles M, Fuchs CS, ... ... Jain RK, et al. Efficacy, safety, pharmacokinetics, and biomarkers of cediranib monotherapy in advanced hepatocellular carcinoma: a phase II study. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 1557-66. PMID 23362324 DOI: 10.1158/1078-0432.CCR-12-3041  0.88
2013 Jain RK, Munn LL, Fukumura D. Lung window preparation in mice. Cold Spring Harbor Protocols. 2013. PMID 23282642 DOI: 10.1101/pdb.prot072678  0.48
2013 Han HS, Martin JD, Lee J, Harris DK, Fukumura D, Jain RK, Bawendi M. Spatial charge configuration regulates nanoparticle transport and binding behavior in vivo. Angewandte Chemie (International Ed. in English). 52: 1414-9. PMID 23255143 DOI: 10.1002/anie.201208331  0.88
2013 Stylianopoulos T, Soteriou K, Fukumura D, Jain RK. Cationic nanoparticles have superior transvascular flux into solid tumors: insights from a mathematical model. Annals of Biomedical Engineering. 41: 68-77. PMID 22855118 DOI: 10.1007/s10439-012-0630-4  0.88
2012 Jain RK. Delivery of molecular and cellular medicine to solid tumors. Advanced Drug Delivery Reviews. 64: 353-365. PMID 24511174 DOI: 10.1016/j.addr.2012.09.011  0.88
2012 Jain RK, Munn LL, Fukumura D. Liver tumor preparation in mice. Cold Spring Harbor Protocols. 2012. PMID 23209146 DOI: 10.1101/pdb.prot072371  0.48
2012 Jain RK, Munn LL, Fukumura D. Pancreatic tumor preparation in mice. Cold Spring Harbor Protocols. 2012. PMID 23209145 DOI: 10.1101/pdb.prot072363  0.48
2012 Jain RK, Munn LL, Fukumura D. Lymphangiography of the mouse ear. Cold Spring Harbor Protocols. 2012: 1179-80. PMID 23118365 DOI: 10.1101/pdb.prot072116  0.48
2012 Jain RK, Munn LL, Fukumura D. Lymphangiography of the mouse tail. Cold Spring Harbor Protocols. 2012: 1177-8. PMID 23118364 DOI: 10.1101/pdb.prot072108  0.48
2012 Kodack DP, Chung E, Yamashita H, Incio J, Duyverman AM, Song Y, Farrar CT, Huang Y, Ager E, Kamoun W, Goel S, Snuderl M, Lussiez A, Hiddingh L, Mahmood S, ... ... Jain RK, et al. Combined targeting of HER2 and VEGFR2 for effective treatment of HER2-amplified breast cancer brain metastases. Proceedings of the National Academy of Sciences of the United States of America. 109: E3119-27. PMID 23071298 DOI: 10.1073/pnas.1216078109  0.88
2012 Huang Y, Yuan J, Righi E, Kamoun WS, Ancukiewicz M, Nezivar J, Santosuosso M, Martin JD, Martin MR, Vianello F, Leblanc P, Munn LL, Huang P, Duda DG, Fukumura D, ... Jain RK, et al. Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy. Proceedings of the National Academy of Sciences of the United States of America. 109: 17561-6. PMID 23045683 DOI: 10.1073/pnas.1215397109  0.88
2012 Jain RK, Munn LL, Fukumura D. Mammary fat pad tumor preparation in mice. Cold Spring Harbor Protocols. 2012: 1115-6. PMID 23028076 DOI: 10.1101/pdb.prot071514  0.48
2012 Jain RK, Munn LL, Fukumura D. Mammary fat pad chamber preparation in mice. Cold Spring Harbor Protocols. 2012: 1113-4. PMID 23028075 DOI: 10.1101/pdb.prot071506  0.48
2012 Liu J, Liao S, Diop-Frimpong B, Chen W, Goel S, Naxerova K, Ancukiewicz M, Boucher Y, Jain RK, Xu L. TGF-β blockade improves the distribution and efficacy of therapeutics in breast carcinoma by normalizing the tumor stroma. Proceedings of the National Academy of Sciences of the United States of America. 109: 16618-23. PMID 22996328 DOI: 10.1073/pnas.1117610109  0.88
2012 Jain RK, Munn LL, Fukumura D. Corneal pocket assay in rabbits. Cold Spring Harbor Protocols. 2012: 1017-8. PMID 22949714 DOI: 10.1101/pdb.prot070052  0.48
2012 Stylianopoulos T, Martin JD, Chauhan VP, Jain SR, Diop-Frimpong B, Bardeesy N, Smith BL, Ferrone CR, Hornicek FJ, Boucher Y, Munn LL, Jain RK. Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors. Proceedings of the National Academy of Sciences of the United States of America. 109: 15101-8. PMID 22932871 DOI: 10.1073/pnas.1213353109  0.88
2012 Jain RK, Munn LL, Fukumura D. Rabbit ear chambers. Cold Spring Harbor Protocols. 2012: 813-14. PMID 22753607 DOI: 10.1101/pdb.prot070045  0.48
2012 Kozin SV, Duda DG, Munn LL, Jain RK. Neovascularization after irradiation: what is the source of newly formed vessels in recurring tumors? Journal of the National Cancer Institute. 104: 899-905. PMID 22572994 DOI: 10.1093/jnci/djs239  0.48
2012 Chauhan VP, Stylianopoulos T, Martin JD, Popovi? Z, Chen O, Kamoun WS, Bawendi MG, Fukumura D, Jain RK. Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner. Nature Nanotechnology. 7: 383-8. PMID 22484912 DOI: 10.1038/nnano.2012.45  0.88
2012 Vakoc BJ, Fukumura D, Jain RK, Bouma BE. Cancer imaging by optical coherence tomography: preclinical progress and clinical potential. Nature Reviews. Cancer. 12: 363-8. PMID 22475930 DOI: 10.1038/nrc3235  0.88
2012 Stylianopoulos T, Wong C, Bawendi MG, Jain RK, Fukumura D. Multistage nanoparticles for improved delivery into tumor tissue. Methods in Enzymology. 508: 109-30. PMID 22449923 DOI: 10.1016/B978-0-12-391860-4.00006-9  0.88
2011 Chauhan VP, Stylianopoulos T, Boucher Y, Jain RK. Delivery of molecular and nanoscale medicine to tumors: transport barriers and strategies. Annual Review of Chemical and Biomolecular Engineering. 2: 281-98. PMID 22432620 DOI: 10.1146/annurev-chembioeng-061010-114300  0.88
2011 Chauhan VP, Popovi? Z, Chen O, Cui J, Fukumura D, Bawendi MG, Jain RK. Fluorescent nanorods and nanospheres for real-time in vivo probing of nanoparticle shape-dependent tumor penetration. Angewandte Chemie (International Ed. in English). 50: 11417-20. PMID 22113800 DOI: 10.1002/anie.201104449  0.88
2011 Garkavtsev I, Chauhan VP, Wong HK, Mukhopadhyay A, Glicksman MA, Peterson RT, Jain RK. Dehydro-alpha-lapachone, a plant product with antivascular activity. Proceedings of the National Academy of Sciences of the United States of America. 108: 11596-601. PMID 21709229 DOI: 10.1073/pnas.1104225108  0.88
2011 Liu J, Liao S, Huang Y, Samuel R, Shi T, Naxerova K, Huang P, Kamoun W, Jain RK, Fukumura D, Xu L. PDGF-D improves drug delivery and efficacy via vascular normalization, but promotes lymphatic metastasis by activating CXCR4 in breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3638-48. PMID 21459800 DOI: 10.1158/1078-0432.CCR-10-2456  0.88
2011 Diop-Frimpong B, Chauhan VP, Krane S, Boucher Y, Jain RK. Losartan inhibits collagen I synthesis and improves the distribution and efficacy of nanotherapeutics in tumors. Proceedings of the National Academy of Sciences of the United States of America. 108: 2909-14. PMID 21282607 DOI: 10.1073/pnas.1018892108  0.88
2011 Wong C, Stylianopoulos T, Cui J, Martin J, Chauhan VP, Jiang W, Popovic Z, Jain RK, Bawendi MG, Fukumura D. Multistage nanoparticle delivery system for deep penetration into tumor tissue. Proceedings of the National Academy of Sciences of the United States of America. 108: 2426-31. PMID 21245339 DOI: 10.1073/pnas.1018382108  0.88
2010 Stylianopoulos T, Diop-Frimpong B, Munn LL, Jain RK. Diffusion anisotropy in collagen gels and tumors: the effect of fiber network orientation. Biophysical Journal. 99: 3119-28. PMID 21081058 DOI: 10.1016/j.bpj.2010.08.065  0.88
2010 Popovi? Z, Liu W, Chauhan VP, Lee J, Wong C, Greytak AB, Insin N, Nocera DG, Fukumura D, Jain RK, Bawendi MG. A nanoparticle size series for in vivo fluorescence imaging. Angewandte Chemie (International Ed. in English). 49: 8649-52. PMID 20886481 DOI: 10.1002/anie.201003142  0.88
2010 Allen PM, Liu W, Chauhan VP, Lee J, Ting AY, Fukumura D, Jain RK, Bawendi MG. InAs(ZnCdS) quantum dots optimized for biological imaging in the near-infrared. Journal of the American Chemical Society. 132: 470-1. PMID 20025222 DOI: 10.1021/ja908250r  0.88
2009 Chauhan VP, Lanning RM, Diop-Frimpong B, Mok W, Brown EB, Padera TP, Boucher Y, Jain RK. Multiscale measurements distinguish cellular and interstitial hindrances to diffusion in vivo. Biophysical Journal. 97: 330-6. PMID 19580771 DOI: 10.1016/j.bpj.2009.03.064  0.88
2009 Jain RK. A new target for tumor therapy New England Journal of Medicine. 360. PMID 19535806 DOI: 10.1056/NEJMcibr0902054  0.88
2008 Jain RK. Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer Nature Reviews Cancer. 8: 309-316. PMID 18337733 DOI: 10.1038/nrc2346  0.88
2008 Jain RK. Taming vessels to treat cancer Scientific American. 298: 56-63. PMID 18225696  0.88
2006 Reddy ST, Berk DA, Jain RK, Swartz MA. A sensitive in vivo model for quantifying interstitial convective transport of injected macromolecules and nanoparticles. Journal of Applied Physiology (Bethesda, Md. : 1985). 101: 1162-9. PMID 16763103 DOI: 10.1152/japplphysiol.00389.2006  0.36
2005 Jain RK. Antiangiogenic therapy for cancer: current and emerging concepts Oncology (Williston Park, N.Y.). 19: 7-16. PMID 15934498  0.88
2005 Jain RK. Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy Science. 307: 58-62. PMID 15637262 DOI: 10.1126/science.1104819  0.88
2005 Sharma RC, Jain RK. Conductivity, viscosity and volumetric behavior of molten hydrates of M3+ and M2+ ions Journal of the Indian Chemical Society. 82: 1079-1086.  0.88
2004 Sarkar R, Jain RK. Pachyoncyhia congenita type 2 [6] Pediatric Dermatology. 21: 517-518. PMID 15283812 DOI: 10.1111/j.0736-8046.2004.21430.x  0.88
2003 Jain RK. Molecular regulation of vessel maturation Nature Medicine. 9: 685-693. PMID 12778167 DOI: 10.1038/nm0603-685  0.88
2002 Jain RK. Angiogenesis and lymphangiogenesis in tumors: Insights from intravital microscopy Cold Spring Harbor Symposia On Quantitative Biology. 67: 239-248. PMID 12858546  0.88
2002 Jain RK. Tumor angiogenesis and accessibility: role of vascular endothelial growth factor Seminars in Oncology. 29: 3-9. PMID 12516032  0.88
2002 Anuradha, Jain RK. Angioarchitecture of the epididymis in camel (Camelus dromedarius) Indian Journal of Animal Sciences. 72: 368-371.  0.88
2002 Anuradha, Jain RK. Venography of renal vein with special reference to the venous drainage of kidney in camel (Camelus dromedarius) Indian Veterinary Journal. 79: 1047-1050.  0.88
2001 Jain RK. Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapy Nature Medicine. 7: 987-989. PMID 11533692 DOI: 10.1038/nm0901-987  0.88
2001 Jain RK. Delivery of molecular medicine to solid tumors: Lessons from in vivo imaging of gene expression and function Journal of Controlled Release. 74: 7-25. PMID 11489479 DOI: 10.1016/S0168-3659(01)00306-6  0.88
2001 Jain RK. Clearing the smoke on nicotine and angiogenesis Nature Medicine. 7: 775-777. PMID 11433337 DOI: 10.1038/89889  0.88
1999 Jain RK. Transport of molecules, particles, and cells in solid tumors Annual Review of Biomedical Engineering. 241-263. PMID 11701489  0.88
1999 Jain RK. Understanding barriers to drug delivery: High resolution in vivo imaging is key Clinical Cancer Research. 5: 1605-1606. PMID 10430057  0.88
1999 Jain RK. Role of physiology in drug delivery into tumors Proceedings of the Controlled Release Society. 84.  0.88
1999 Jain RK, Anuradha. Venography of testicular vein with special reference to the venous drainage of the testis in camel (Camelus dromedarius) Journal of Camel Practice and Research. 6: 317-321.  0.88
1998 Jain RK. The next frontier of molecular medicine: Delivery of therapeutics Nature Medicine. 4: 655-657. PMID 9623964 DOI: 10.1038/nm0698-655  0.88
1998 Jain RK. Integrative pathophysiology of solid tumors: Role in detection and treatment Cancer Journal From Scientific American. 4. PMID 9619271  0.88
1997 Jain RK. Potential and limitations of radioimmunodetection and radioimmunotherapy with monoclonal antibodies Journal of Nuclear Medicine. 38: 731-741. PMID 9170438  0.88
1997 Jain RK. The Eugene M. Landis Award Lecture 1996. Delivery of molecular and cellular medicine to solid tumors Microcirculation (New York, N.Y. : 1994). 4: 1-23. PMID 9110280  0.88
1996 Jain RK. 1995 Whitaker lecture: Delivery of molecules, particles, and cells to solid tumors Annals of Biomedical Engineering. 24: 457-473. PMID 8841721  0.88
1996 Jain RK, Matta KL. Chemical synthesis of a hexasaccharide comprising the LewisX determinant linked β-(1 → 6) to a linear trimannosyl core and the precursor pentasaccharide lacking fucose Carbohydrate Research. 282: 101-111. PMID 8721739 DOI: 10.1016/0008-6215(95)00376-2  0.88
1996 Jain RK. Delivery of molecular medicine to solid tumors Science. 271: 1079-1080. PMID 8599082 DOI: 10.1126/science.271.5252.1079  0.88
1994 Jain RK. Barriers to drug delivery in solid tumors Scientific American. 271: 58-65. PMID 8066425  0.88
1994 Melder RJ, Jain RK. Reduction of rigidity in human activated natural killer cells by thioglycollate treatment Journal of Immunological Methods. 175: 69-77. PMID 7930640 DOI: 10.1016/0022-1759(94)90332-8  0.88
1994 Martin GR, Jain RK. Noninvasive measurement of interstitial pH profiles in normal and neoplastic tissue using fluorescence ratio imaging microscopy. Cancer Research. 54: 5670-4. PMID 7923215  0.88
1994 Jain RK. Transport Phenomena in Tumors Advances in Chemical Engineering. 19: 129-200. DOI: 10.1016/S0065-2377(08)60214-8  0.88
1993 Martin GR, Jain RK. Fluorescence ratio imaging measurement of pH gradients: calibration and application in normal and tumor tissues. Microvascular Research. 46: 216-30. PMID 8246820 DOI: 10.1006/mvre.1993.1048  0.88
1992 Jain RK, Matta KL. Synthesis of oligosaccharides containing the X-antigenic trisaccharide (α-l-Fucp-(1→3)-[β-d-Galp-(1→4)]-β-d-GlcpNAc) at their nonreducing ends Carbohydrate Research. 226: 91-100. PMID 1499025 DOI: 10.1016/0008-6215(92)84057-Y  0.88
1992 Melder RJ, Jain RK. Kinetics of interleukin-2 induced changes in rigidity of human natural killer cells Cell Biophysics. 20: 161-176. PMID 1285298 DOI: 10.1007/BF02823656  0.88
1992 Jain RK, Matta KL. Methyl 2,3,4,6-tetra-O-(4-methoxybenzyl)-1-thio-β-D-glucopyranoside-a novel reagent for α-glycosylation towards nitrophenyl or benzyl glycosides Bioorganic and Medicinal Chemistry Letters. 2: 1707-1712. DOI: 10.1016/S0960-894X(00)80461-8  0.88
1991 Jain RK. Therapeutic implications of tumor physiology Current Opinion in Oncology. 3: 1105-1108. PMID 1843113  0.88
1991 Stock RJ, Jain RK. Assessment of fluid movement in tissues by fluorescence photobleaching Annals of Biomedical Engineering. 19: 555.  0.88
1990 Jain RK. Physiological barriers to delivery of monoclonal antibodies and other macromolecules in tumors Cancer Research. 50. PMID 2404582  0.88
1990 Jain RK. Vascular and interstitial barriers to delivery of therapeutic agents in tumors Cancer and Metastasis Review. 9: 253-266. PMID 2292138 DOI: 10.1007/BF00046364  0.88
1990 Jain RK. Tumor physiology and antibody delivery Frontiers of Radiation Therapy and Oncology. 24: 32-46; discussion 64. PMID 2187763  0.88
1990 Jain RK, Matta KL. Synthesis of methyl 2-O-(sodium α-l-fucopyranosyl 3- and 4-sulfate)-α-l-fucopyranoside Carbohydrate Research. 208: 280-286. PMID 2085815 DOI: 10.1016/0008-6215(90)80112-G  0.88
1990 Jain RK, Matta KL. Synthesis of the sodium salts of methyl 2-O-α-l-fucopyranosyl-α-l-fucopyranoside 3- and 4-sulfate Carbohydrate Research. 208: 51-58. PMID 1964872 DOI: 10.1016/0008-6215(90)80084-G  0.88
1990 Jain RK, Matta KL. Methyl 3,4-0-isopropylidene-2-O-(4-methoxybenzyl)-1-thio-β-L-fucopyranoside - a novel, efficient glycosylating reagent for the synthesis of linear and other α-L-fucosyl oligosaccharides Tetrahedron Letters. 31: 4325-4328. DOI: 10.1016/S0040-4039(00)97612-3  0.88
1989 Chary SR, Jain RK. Direct measurement of interstitial convection and diffusion of albumin in normal and neoplastic tissues by fluorescence photobleaching Proceedings of the National Academy of Sciences of the United States of America. 86: 5385-5389. PMID 2748592  0.88
1989 Jain RK. Delivery of novel therapeutic agents in tumors: Physiological barriers and strategies Journal of the National Cancer Institute. 81: 570-576. PMID 2649688 DOI: 10.1093/jnci/81.8.570  0.88
1988 Ward KA, Jain RK. Invited review: Response of tumours to hyperglycaemia: Characterization, significance and role in hyperthermia International Journal of Hyperthermia. 4: 223-250. PMID 3290346 DOI: 10.3109/02656738809051100  0.88
1988 Jain RK. Determinants of Tumor Blood Flow: A Review Cancer Research. 48: 2641-2658. PMID 3282647  0.88
1988 Jain RK. Transvascular and interstitial transport in tumors Advances in Experimental Medicine and Biology. 242: 215-220. PMID 2469315  0.88
1987 Jain RK. Transport of Molecules in the Tumor Interstitium: A Review Cancer Research. 47: 3039-3051. PMID 3555767  0.88
1987 Jain RK. Transport of molecules across tumor vasculature Cancer and Metastasis Review. 6: 559-593. PMID 3327633 DOI: 10.1007/BF00047468  0.88
1985 Jain RK. Transport of macromolecules in tumor microcirculation Biotechnology Progress™. 1: 81-94. DOI: 10.1002/btpr.5420010205  0.88
1980 Jain RK. Temperature distributions in normal and neoplastic tissues during normothermia and hyperthermia Annals of the New York Academy of Sciences. 335: 48-66. PMID 6931539 DOI: 10.1111/j.1749-6632.1980.tb50736.x  0.88
1979 Jain RK. TRANSIENT TEMPERATURE DISTRIBUTIONS IN AN INFINITE, PERFUSED MEDIUM DUE TO A TIME-DEPENDENT, SPHERICAL HEAT SOURCE Journal of Biomechanical Engineering. 101: 82-86.  0.88
1974 Jain RK. Vibration of fluid-filled, orthotropic cylindrical shells Journal of Sound and Vibration. 37: 379-388. DOI: 10.1016/S0022-460X(74)80253-1  0.88
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