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Gregory K. Friestad - Publications

Affiliations: 
1998-2005 Chemistry University of Vermont, Burlington, VT, United States 
 2005- Chemistry University of Iowa, Iowa City, IA 
Area:
Organic Chemistry, Inorganic Chemistry
Website:
https://chem.uiowa.edu/people/gregory-k-friestad
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67 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Li M, Banerjee K, Friestad GK. Diastereocontrol in Radical Addition to β-Benzyloxy Hydrazones: Revised Approach to Tubuvaline and Synthesis of -Benzyltubulysin V Benzyl Ester. The Journal of Organic Chemistry. PMID 34636574 DOI: 10.1021/acs.joc.1c01798  0.832
2020 Friedrich RM, Friestad GK. Inspirations from tetrafibricin and related polyketides: new methods and strategies for 1,5-polyol synthesis. Natural Product Reports. PMID 32412021 DOI: 10.1039/C9Np00070D  0.78
2020 Li M, Goff L, Friestad GK. Aromatic N-heterocycles in Mn-mediated radical additions to N-acylhydrazones Tetrahedron Letters. 61: 152058. DOI: 10.1016/J.Tetlet.2020.152058  0.598
2019 Cullen STJ, Friestad GK. Alkyl Radical Addition to Aliphatic and Aromatic -Acylhydrazones Using an Organic Photoredox Catalyst. Organic Letters. PMID 31560554 DOI: 10.1021/Acs.Orglett.9B03053  0.585
2018 Friedrich RM, Bell JQ, Garcia A, Shen Z, Friestad GK. Unified Strategy for 1,5,9- and 1,5,7-Triols via Configuration-Encoded 1,5-Polyol Synthesis: Preparation and Coupling of C15-C25 and C26-C40 Fragments of Tetrafibricin. The Journal of Organic Chemistry. PMID 30372076 DOI: 10.1021/Acs.Joc.8B02034  0.809
2018 Friedrich RM, Sreenilayam G, Hackbarth J, Friestad GK. Unified Strategy for 1,5,9- and 1,5,7-Triols via Configuration-Encoded 1,5-Polyol Synthesis: Enantioselective Preparation of γ-Sulfonyl-α-silyloxyaldehydes and Iterative Julia-Kocienski Coupling. The Journal of Organic Chemistry. PMID 30365891 DOI: 10.1021/Acs.Joc.8B02033  0.806
2017 Ibrahim SM, Banerjee K, Slater KA, Friestad GK. A Tamao–Fleming oxidation route to dipeptides bearing N,O-acetal functionality Tetrahedron Letters. 58: 4864-4866. DOI: 10.1016/J.Tetlet.2017.11.036  0.778
2017 Friedrich RM, Friestad GK. Access to ananti,syn-1,5,7-Triol by Configuration-Encoded 1,5-Polyol Synthesis: The C15-C25 Fragment of Tetrafibricin European Journal of Organic Chemistry. 2017: 1961-1964. DOI: 10.1002/Ejoc.201700373  0.795
2016 Friestad GK, Banerjee K, Marié JC, Mali U, Yao L. Stereoselective access to tubuphenylalanine and tubuvaline: improved Mn-mediated radical additions and assembly of a tubulysin tetrapeptide analog. The Journal of Antibiotics. PMID 26883395 DOI: 10.1038/Ja.2016.7  0.814
2015 Slater KA, Friestad GK. Mn-Mediated Radical-Ionic Annulations of Chiral N-Acylhydrazones. The Journal of Organic Chemistry. 80: 6432-40. PMID 25992979 DOI: 10.1021/Acs.Joc.5B00863  0.829
2014 Friestad GK. Control of asymmetry in the radical addition approach to chiral amine synthesis. Topics in Current Chemistry. 343: 1-32. PMID 24085561 DOI: 10.1007/128_2013_481  0.535
2012 Friestad GK, Ji A, Baltrusaitis J, Korapala CS, Qin J. Scope of stereoselective Mn-mediated radical addition to chiral hydrazones and application in a formal synthesis of quinine. The Journal of Organic Chemistry. 77: 3159-80. PMID 22329534 DOI: 10.1021/Jo2026349  0.844
2012 Friestad GK. Radical additions to chiral hydrazones: stereoselectivity and functional group compatibility. Topics in Current Chemistry. 320: 61-91. PMID 21842359 DOI: 10.1007/128_2011_163  0.62
2012 Friestad GK, Sreenilayam G, Cannistra JC, Slominski LM. Preparation of enol ester epoxides and their ring-opening to α-silyloxyaldehydes Tetrahedron Letters. 53: 5064-5067. DOI: 10.1016/J.Tetlet.2012.06.142  0.806
2011 Friestad GK, Ji A, Korapala CS, Qin J. Intermolecular radical addition to N-acylhydrazones as a stereocontrol strategy for alkaloid synthesis: formal synthesis of quinine. Organic & Biomolecular Chemistry. 9: 4039-43. PMID 21537510 DOI: 10.1039/C1Ob05219E  0.849
2011 Friestad GK, Sreenilayam G. 1,5-Polyols: Challenging motifs for configurational assignment and synthesis Pure and Applied Chemistry. 83: 461-478. DOI: 10.1351/Pac-Con-10-10-19  0.792
2010 Friestad GK, Sreenilayam G. Versatile configuration-encoded strategy for rapid synthesis of 1,5-polyol stereoisomers. Organic Letters. 12: 5016-9. PMID 20939544 DOI: 10.1021/Ol1021417  0.815
2010 Friestad GK. ChemInform Abstract: Synthesis of Alkyl- and Cycloalkylamines by Addition of Carbanions to Azomethines Cheminform. 41: no-no. DOI: 10.1002/CHIN.201050236  0.377
2010 Friestad GK. ChemInform Abstract: Synthesis of Alkyl- and Cycloalkylamines by Reaction of Acetals with Organometallic Reagents Cheminform. 41: no-no. DOI: 10.1002/chin.201046233  0.342
2010 Smith III AB, Friestad GK, Barbosa J, Bertounesque E, Duan JJ, Hull KG, Iwashima M, Qiu Y, Spoors PG, Salvatore BA. ChemInform Abstract: Total Synthesis of (+)-Calyculin A (Ia) and (-)-Calyculin B (Ib): Cyanotetraene Construction, Asymmetric Synthesis of the C(26-37) Oxazole, Fragment Assembly, and Final Elaboration. Cheminform. 31: no-no. DOI: 10.1002/chin.200010237  0.742
2010 Smith ABI, Friestad GK, Duan JJ, Barbosa J, Hull KG, Iwashima M, Qiu Y, Spoors PG, Bertounesque E, Salvatore BA. ChemInform Abstract: Total Synthesis of (+)-Calyculin A and (-)-Calyculin B. Cheminform. 30: no-no. DOI: 10.1002/chin.199912235  0.693
2010 Friestad GK. Organomanganese‐Mediated Radical Reactions Patai's Chemistry of Functional Groups. DOI: 10.1002/9780470682531.Pat0532  0.489
2009 Friestad GK, Lee HJ. Trans-2,5-disubstituted tetrahydrofurans via addition of carbon nucleophiles to the strained bicyclic acetal 2,7-dioxabicyclo[2.2.1]heptane. Organic Letters. 11: 3958-61. PMID 19663466 DOI: 10.1021/Ol901613K  0.33
2009 Friestad GK, Banerjee K. Synthesis of gamma-amino esters via Mn-mediated radical addition to chiral gamma-hydrazonoesters. Organic Letters. 11: 1095-8. PMID 19199819 DOI: 10.1021/Ol802932V  0.75
2009 Friestad GK, Wu Y. Intermolecular nonreductive alkylation of enamides via radical-polar crossover. Organic Letters. 11: 819-22. PMID 19199766 DOI: 10.1021/Ol8028077  0.391
2009 Friestad GK, Banerjee K. ChemInform Abstract: Synthesis of γ-Amino Esters via Mn-Mediated Radical Addition to Chiral γ-Hydrazonoesters. Cheminform. 40. DOI: 10.1002/chin.200930055  0.73
2008 Friestad GK, Ji A. Mn-mediated coupling of alkyl iodides and ketimines: a radical addition route to alpha,alpha-disubstituted alpha-aminoesters. Organic Letters. 10: 2311-3. PMID 18461956 DOI: 10.1021/Ol800733B  0.608
2008 Friestad GK, Jiang T, Fioroni GM. Stereocontrol in radical Mannich equivalents for aminosugar synthesis: haloacetal and 2-(phenylthio)vinyl tethered radical additions to α-hydroxyhydrazones Tetrahedron. 64: 11549-11557. DOI: 10.1016/J.Tet.2008.10.013  0.623
2008 Friestad GK, Ji A. ChemInform Abstract: Mn-Mediated Coupling of Alkyl Iodides and Ketimines: A Radical Addition Route to α,α-Disubstituted α-Aminoesters. Cheminform. 39. DOI: 10.1002/CHIN.200842044  0.551
2007 Friestad GK, Mathies AK. Effects of alpha-Alkoxy Substitution and Conformational Constraints on 6-exo Radical Cyclizations of Hydrazones via Reversible Thiyl and Stannyl Additions. Tetrahedron. 63: 9373-9381. PMID 18797497 DOI: 10.1016/J.Tet.2007.06.117  0.83
2007 Korapala CS, Qin J, Friestad GK. Quinine synthesis studies: a radical-ionic annulation via Mn-mediated addition to chiral N-acylhydrazones. Organic Letters. 9: 4243-6. PMID 17850094 DOI: 10.1021/Ol7017938  0.831
2007 Friestad GK, Jiang T, Mathies AK. Aldehyde-selective Wacker oxidation in a thiyl-mediated vinyl group transfer route to daunosamine. Organic Letters. 9: 777-80. PMID 17284042 DOI: 10.1021/Ol063010Z  0.814
2007 Friestad GK, Jiang T, Mathies AK. Corrigendum to "Enhanced reactivity in radical cyclizations of hydrazones using the silicon-tethered 1-bromovinyl group" [Tetrahedron 63 (2007) 3964] (DOI:10.1016/j.tet.2007.03.017) Tetrahedron. 63: 13039. DOI: 10.1016/J.Tet.2007.10.059  0.784
2007 Friestad GK, Jiang T, Mathies AK. Enhanced reactivity in radical cyclizations of hydrazones using the silicon-tethered 1-bromovinyl group Tetrahedron. 63: 3964-3972. DOI: 10.1016/J.Tet.2007.03.017  0.836
2007 Friestad GK, Mathies AK. Recent developments in asymmetric catalytic addition to C{double bond, long}N bonds Tetrahedron. 63: 2541-2569. DOI: 10.1016/j.tet.2006.11.076  0.813
2007 Friestad GK, Mathies AK. Recent Development in Asymmetric Catalytic Addition to C=N Bonds Cheminform. 38. DOI: 10.1016/J.Tet.2006.11.076  0.819
2006 Friestad GK, Marié JC, Suh Y, Qin J. Mn-mediated coupling of alkyl iodides and chiral N-acylhydrazones: optimization, scope, and evidence for a radical mechanism. The Journal of Organic Chemistry. 71: 7016-27. PMID 16930057 DOI: 10.1021/Jo061158Q  0.847
2006 Friestad GK, Korapala CS, Ding H. Dual activation in asymmetric allylsilane addition to chiral N-acylhydrazones: method development, mechanistic studies, and elaboration of homoallylic amine adducts. The Journal of Organic Chemistry. 71: 281-9. PMID 16388647 DOI: 10.1021/Jo052037D  0.841
2006 Ding H, Friestad GK. Strecker reactions of chiral N-acylhydrazones Heterocycles. 70: 185-199. DOI: 10.3987/Com-06-S(W)3  0.501
2006 Friestad G, Marié J, Suh Y, Qin J. Mn-Mediated Radical Diastereoselective Alkylation of N-Acylhydrazones Synfacts. 2006: 1161-1161. DOI: 10.1055/s-2006-949486  0.546
2005 Friestad GK, Draghici C, Soukri M, Qin J. Radical addition approach to asymmetric amine synthesis: design, implementation, and comparison of chiral N-acylhydrazones. The Journal of Organic Chemistry. 70: 6330-8. PMID 16050694 DOI: 10.1021/Jo050756M  0.848
2005 Friestad GK, Fioroni GM. Haloacetal radical cyclizations of alpha- and beta-hydroxyhydrazones. Organic Letters. 7: 2393-6. PMID 15932206 DOI: 10.1021/Ol050663R  0.328
2005 Ding H, Friestad GK. Asymmetric addition of allylic nucleophiles to imino compounds Synthesis. 2815-2829. DOI: 10.1055/S-2005-872181  0.427
2005 Friestad GK. Chiral N-acylhydrazones: Versatile imino acceptors for asymmetric amine synthesis European Journal of Organic Chemistry. 3157-3172. DOI: 10.1002/Ejoc.200500232  0.596
2004 Friestad GK, Marié JC, Deveau AM. Stereoselective Mn-mediated coupling of functionalized iodides and hydrazones: a synthetic entry to the tubulysin gamma-amino acids. Organic Letters. 6: 3249-52. PMID 15355024 DOI: 10.1021/Ol048986V  0.824
2004 Ding H, Friestad GK. Trifluoroacetyl-activated nitrogen-nitrogen bond cleavage of hydrazines by samarium(II) iodide. Organic Letters. 6: 637-40. PMID 14961642 DOI: 10.1021/Ol036480R  0.659
2004 Friestad GK, Massari SE. A silicon tether approach for addition of functionalized radicals to chiral alpha-hydroxyhydrazones: diastereoselective additions of hydroxymethyl and vinyl synthons. The Journal of Organic Chemistry. 69: 863-75. PMID 14750816 DOI: 10.1021/Jo035405R  0.444
2004 Friestad GK, Jiang T, Mathies AK, Massari SE. Silicon-containing heterocycles in stereocontrolled radical additions to chiral hydrazones Phosphorus, Sulfur and Silicon and the Related Elements. 179: 955-956. DOI: 10.1080/10426500490429022  0.812
2004 Ding H, Friestad GK. Allyltrimethoxysilane addition to N-acylhydrazones: Two catalytic methods employing CuCl and fluoride Synthesis. 2216-2221. DOI: 10.1055/S-2004-829190  0.456
2003 Friestad GK, Shen Y, Ruggles EL. Enantioselective radical addition to N-acyl hydrazones mediated by chiral Lewis acids. Angewandte Chemie (International Ed. in English). 42: 5061-3. PMID 14595632 DOI: 10.1002/Anie.200352104  0.832
2003 Friestad GK, Jiang T, Fioroni GM. Tandem thiyl radical addition and cyclization of chiral hydrazones using a silicon-tethered alkyne Tetrahedron Asymmetry. 14: 2853-2856. DOI: 10.1016/S0957-4166(03)00540-8  0.535
2003 Qin J, Friestad GK. Stereocontrol in hydride addition to ketone-derived chiral N-acylhydrazones Tetrahedron. 59: 6393-6402. DOI: 10.1016/S0040-4020(03)01091-3  0.659
2002 Shen Y, Friestad GK. Comparison of electrophilic amination reagents for N-amination of 2-oxazolidinones and application to synthesis of chiral hydrazones. The Journal of Organic Chemistry. 67: 6236-9. PMID 12182669 DOI: 10.1021/Jo0259663  0.767
2001 Friestad GK, Ding H. Asymmetric Allylsilane Additions to Enantiopure N-Acylhydrazones with Dual Activation by Fluoride and In(OTf)(3) We thank the National Science Foundation (Vermont EPSCoR) and the University of Vermont for generous support. Angewandte Chemie (International Ed. in English). 40: 4491-4493. PMID 12404456 DOI: 10.1002/1521-3773(20011203)40:23<4491::Aid-Anie4491>3.0.Co;2-8  0.494
2001 Friestad GK, Qin J. Intermolecular alkyl radical addition to chiral N-acylhydrazones mediated by manganese carbonyl [14] Journal of the American Chemical Society. 123: 9922-9923. PMID 11583567 DOI: 10.1021/Ja011312K  0.657
2001 Friestad GK. Addition of carbon-centered radicals to imines and related compounds Tetrahedron. 57: 5461-5496. DOI: 10.1016/S0040-4020(01)00384-2  0.325
2001 Friestad GK, Ding H. Asymmetric allylsilane additions to enantiopure N-acylhydrazones with dual activation by fluoride and In(OTF)3 Angewandte Chemie - International Edition. 40: 4491-4493. DOI: 10.1002/1521-3757(20011203)113:23<4623::Aid-Ange4623>3.0.Co;2-G  0.46
2000 Friestad GK, Massari SE. Diastereoselective vinyl addition to chiral hydrazones via tandem thiyl radical addition and silicon-tethered cyclization Organic Letters. 2: 4237-4240. DOI: 10.1021/Ol0067991  0.502
2000 Friestad GK, Qin J. Highly stereoselective intermolecular radical addition to aldehyde hydrazones from a chiral 3-amino-2-oxazolidinone [16] Journal of the American Chemical Society. 122: 8329-8330. DOI: 10.1021/ja002173u  0.564
1999 Friestad GK. A silicon tether approach for diastereocontrol in radical addition to chiral hydrazones Organic Letters. 1: 1499-1501. DOI: 10.1021/Ol991059H  0.499
1999 Smith AB, Friestad GK, Barbosa J, Bertounesque E, Duan JJW, Hull KG, Iwashima M, Qiu Y, Spoors PG, Salvatore BA. Total synthesis of (+)-calyculin A and (-)-calyculin B: Cyanotetraene construction, asymmetric synthesis of the C(26-37) oxazole, fragment assembly, and final elaboration Journal of the American Chemical Society. 121: 10478-10486. DOI: 10.1021/Ja992135E  0.745
1999 Smith AB, Friestad GK, Barbosa J, Bertounesque E, Hull KG, Iwashima M, Qiu Y, Salvatore BA, Spoors PG, Duan JJW. Total synthesis of (+)-calyculin A and (-)-calyculin B: Asymmetric synthesis of the C(9-25) spiroketal dipropionate subunit Journal of the American Chemical Society. 121: 10468-10477. DOI: 10.1021/Ja992134M  0.771
1999 Grubb LM, Dowdy AL, Blanchette HS, Friestad GK, Branchaud BP. An approach to (+)-pancratistatin from D-glucose: A conformational lock solves a stereochemical problem Tetrahedron Letters. 40: 2691-2694. DOI: 10.1016/S0040-4039(99)00334-2  0.627
1998 Smith AB III, Friestad GK, Duan JJW, Barbosa J, Hull KG, Iwashima M, Qiu Y, Spoors PG, Bertounesque E, Salvatore BA. Total Synthesis of (+)-Calyculin A and (-)-Calyculin B The Journal of Organic Chemistry. 63: 7596-7597. DOI: 10.1021/Jo981813X  0.705
1998 Smith AB, Cho YS, Friestad GK. Convenient Wacker oxidations with substoichiometric cupric acetate Tetrahedron Letters. 39: 8765-8768. DOI: 10.1016/S0040-4039(98)01992-3  0.36
1997 Friestad GK, Branchaud BP. A new approach to the pancratistatin C-ring from D-Glucose: Ferrier rearrangement, pseudoinversion and Pd-catalyzed cyclizations Tetrahedron Letters. 38: 5933-5936. DOI: 10.1016/S0040-4039(97)01325-7  0.695
1995 Friestad GK, Branchaud BP. Intramolecular Pd-catalyzed aryl-enone conjugate additions. Control of reductive vs non-reductive cyclization Tetrahedron Letters. 36: 7047-7050. DOI: 10.1016/0040-4039(95)01460-Y  0.663
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