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Kamila Naxerova, Ph.D. - Publications

Affiliations: 
2014 Biology: Medical Sciences, Division of Harvard University, Cambridge, MA, United States 
Area:
Genetics, Oncology
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28/62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Burr R, Leshchiner I, Costantino CL, Blohmer M, Sundaresan T, Cha J, Seeger K, Guay S, Danysh BP, Gore I, Jacobs RA, Slowik K, Utro F, Rhrissorrakrai K, Levovitz C, ... ... Naxerova K, et al. Germline mutations and developmental mosaicism underlying -mutant lung cancer. Medrxiv : the Preprint Server For Health Sciences. PMID 37808694 DOI: 10.1101/2023.09.28.23296274  0.303
2023 Datta M, Chatterjee S, Perez EM, Gritsch S, Roberge S, Duquette M, Chen IX, Naxerova K, Kumar AS, Ghosh M, Emblem KE, Ng MR, Ho WW, Kumar P, Krishnan S, et al. Losartan controls immune checkpoint blocker-induced edema and improves survival in glioblastoma mouse models. Proceedings of the National Academy of Sciences of the United States of America. 120: e2219199120. PMID 36724255 DOI: 10.1073/pnas.2219199120  0.415
2022 Ferraro GB, Ali A, Luengo A, Kodack DP, Deik A, Abbott KL, Bezwada D, Blanc L, Prideaux B, Jin X, Posada JM, Chen J, Chin CR, Amoozgar Z, Ferreira R, ... ... Naxerova K, et al. Author Correction: Fatty acid synthesis is required for breast cancer brain metastasis. Nature Cancer. 2: 1243. PMID 35122065 DOI: 10.1038/s43018-021-00283-9  0.351
2021 Ferraro GB, Ali A, Luengo A, Kodack DP, Deik A, Abbott KL, Bezwada D, Blanc L, Prideaux B, Jin X, Possada JM, Chen J, Chin CR, Amoozgar Z, Ferreira R, ... ... Naxerova K, et al. FATTY ACID SYNTHESIS IS REQUIRED FOR BREAST CANCER BRAIN METASTASIS. Nature Cancer. 2: 414-428. PMID 34179825 DOI: 10.1038/s43018-021-00183-y  0.41
2020 Chen IX, Newcomer K, Pauken KE, Juneja VR, Naxerova K, Wu MW, Pinter M, Sen DR, Singer M, Sharpe AH, Jain RK. A bilateral tumor model identifies transcriptional programs associated with patient response to immune checkpoint blockade. Proceedings of the National Academy of Sciences of the United States of America. PMID 32907939 DOI: 10.1073/Pnas.2002806117  0.517
2020 Naxerova K. Defining the role of lymph node metastasis in systemic breast cancer evolution. Ebiomedicine. 57: 102852. PMID 32574957 DOI: 10.1016/J.Ebiom.2020.102852  0.323
2019 Heyde A, Reiter JG, Naxerova K, Nowak MA. Consecutive seeding and transfer of genetic diversity in metastasis. Proceedings of the National Academy of Sciences of the United States of America. PMID 31239334 DOI: 10.1073/Pnas.1819408116  0.427
2019 Chauhan VP, Chen IX, Tong R, Ng MR, Martin JD, Naxerova K, Wu MW, Huang P, Boucher Y, Kohane DS, Langer R, Jain RK. Reprogramming the microenvironment with tumor-selective angiotensin blockers enhances cancer immunotherapy. Proceedings of the National Academy of Sciences of the United States of America. PMID 31040208 DOI: 10.1073/Pnas.1819889116  0.675
2019 Talele NP, Liu H, Naxerova K, Pinter M, Incio J, Lee H, Shigeta K, Ho WW, Michelakos T, Hong TS, Clark JW, Murphy JE, Ryan DP, Deshpande V, Lillemoe KD, et al. Abstract A115: Use of angiotensin system inhibitors is associated with immune activation and longer survival in pancreatic ductal adenocarcinoma patients Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-A115  0.471
2019 Liu H, Ho WW, Naxerova K, Grahovac J, Nia H, Chen I, Posada JM, Schanne DH, Pinter M, Crain J, Qi X, Clark JW, Hong TS, Ryan DP, Huang P, et al. Abstract A18: Angiotensin receptor blockers normalize the pancreatic ductal adenocarcinoma stroma by reprogramming carcinoma-associated fibroblasts Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-A18  0.681
2019 Naxerova K. Tumor mutations are not alone in the plasma Science Translational Medicine. 11: eaaz9767. DOI: 10.1126/Scitranslmed.Aaz9767  0.343
2018 Sack LM, Davoli T, Li MZ, Li Y, Xu Q, Naxerova K, Wooten EC, Bernardi RJ, Martin TD, Chen T, Leng Y, Liang AC, Scorsone KA, Westbrook TF, Wong KK, et al. Profound Tissue Specificity in Proliferation Control Underlies Cancer Drivers and Aneuploidy Patterns. Cell. PMID 29576454 DOI: 10.1016/J.Cell.2018.02.037  0.402
2018 Ng MR, Sabbatino F, Duquette M, Naxerova K, Badeaux M, Ferraro GB, Chin SM, Bezwada D, Brachtel EF, Ferrone S, Jain RK. Abstract LB-057: Hypoxia regulation of antigen presentation machinery expression in breast cancer Tumor Biology. DOI: 10.1158/1538-7445.Am2018-Lb-057  0.44
2017 Naxerova K, Reiter JG, Brachtel E, Lennerz JK, van de Wetering M, Rowan A, Cai T, Clevers H, Swanton C, Nowak MA, Elledge SJ, Jain RK. Origins of lymphatic and distant metastases in human colorectal cancer. Science (New York, N.Y.). 357: 55-60. PMID 28684519 DOI: 10.1126/Science.Aai8515  0.477
2017 Liu H, Naxerova K, Pinter M, Incio J, Lee H, Shigeta K, Ho WW, Crain JA, Jacobson A, Michelakos T, Dias-Santos D, Zanconato A, Hong TS, Clark JW, Murphy JE, et al. Use of Angiotensin System Inhibitors is Associated with Immune Activation and Longer Survival in Non-Metastatic Pancreatic Ductal Adenocarcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28600474 DOI: 10.1158/1078-0432.Ccr-17-0256  0.461
2017 Kodack DP, Askoxylakis V, Ferraro GB, Sheng Q, Badeaux M, Goel S, Qi X, Shankaraiah R, Cao ZA, Ramjiawan RR, Bezwada D, Patel B, Song Y, Costa C, Naxerova K, et al. The brain microenvironment mediates resistance in luminal breast cancer to PI3K inhibition through HER3 activation. Science Translational Medicine. 9. PMID 28539475 DOI: 10.1126/Scitranslmed.Aal4682  0.471
2017 Gupta N, Badeaux M, Liu Y, Naxerova K, Sgroi D, Munn LL, Jain RK, Garkavtsev I. Stress granule-associated protein G3BP2 regulates breast tumor initiation. Proceedings of the National Academy of Sciences of the United States of America. PMID 28096337 DOI: 10.1073/Pnas.1525387114  0.515
2017 Liu H, Pinter M, Incio J, Lee H, Ho W, Crain J, Naxerova K, Di M, Jacobson A, Santos DD, Zanconato A, Deshpande V, Lillemoe K, Castillos CFd, Downes M, et al. Abstract 957: Use of angiotensin system inhibitors is associated with longer overall survival in pancreatic ductal adenocarcinoma patients who underwent pancreatectomy Cancer Research. 77: 957-957. DOI: 10.1158/1538-7445.Am2017-957  0.339
2017 Ferraro GB, Kodack DP, Askoxylakis V, Sheng Q, Badeaux M, Goel S, Qi X, Shankaraiah R, Cao AZ, Ramjiawan RR, Bezwada D, Patel B, Song Y, Costa C, Naxerova K, et al. Abstract 5008: The brain microenvironment mediates resistance in luminal breast cancer to PI3K inhibition through HER3 activation Cancer Research. 77: 5008-5008. DOI: 10.1158/1538-7445.Am2017-5008  0.483
2016 Askoxylakis V, Ferraro GB, Kodack DP, Badeaux M, Shankaraiah RC, Seano G, Kloepper J, Vardam T, Martin JD, Naxerova K, Bezwada D, Qi X, Selig MK, Brachtel E, Duda DG, et al. Preclinical Efficacy of Ado-trastuzumab Emtansine in the Brain Microenvironment. Journal of the National Cancer Institute. 108. PMID 26547932 DOI: 10.1093/Jnci/Djv313  0.463
2015 Naxerova K, Elledge SJ. Taking the brakes off telomerase. Elife. 4. PMID 26194808 DOI: 10.7554/Elife.09519  0.308
2015 Naxerova K, Jain RK. Using tumour phylogenetics to identify the roots of metastasis in humans. Nature Reviews. Clinical Oncology. 12: 258-72. PMID 25601447 DOI: 10.1038/Nrclinonc.2014.238  0.447
2014 Naxerova K, Brachtel E, Salk JJ, Seese AM, Power K, Abbasi B, Snuderl M, Chiang S, Kasif S, Jain RK. Hypermutable DNA chronicles the evolution of human colon cancer. Proceedings of the National Academy of Sciences of the United States of America. 111: E1889-98. PMID 24753616 DOI: 10.1073/Pnas.1400179111  0.478
2014 Rogers MS, Novak K, Zurakowski D, Cryan LM, Blois A, Lifshits E, Bø TH, Oyan AM, Bender ER, Lampa M, Kang SY, Naxerova K, Kalland KH, Straume O, Akslen LA, et al. Spontaneous reversion of the angiogenic phenotype to a nonangiogenic and dormant state in human tumors. Molecular Cancer Research : McR. 12: 754-64. PMID 24574516 DOI: 10.1158/1541-7786.Mcr-13-0532-T  0.418
2012 Liu J, Liao S, Diop-Frimpong B, Chen W, Goel S, Naxerova K, Ancukiewicz M, Boucher Y, Jain RK, Xu L. TGF-β blockade improves the distribution and efficacy of therapeutics in breast carcinoma by normalizing the tumor stroma. Proceedings of the National Academy of Sciences of the United States of America. 109: 16618-23. PMID 22996328 DOI: 10.1073/Pnas.1117610109  0.623
2012 Helman E, Naxerova K, Kohane IS. DNA hypermethylation in lung cancer is targeted at differentiation- associated genes Oncogene. 31: 1181-1188. PMID 21804601 DOI: 10.1038/Onc.2011.307  0.321
2011 Liu J, Liao S, Huang Y, Samuel R, Shi T, Naxerova K, Huang P, Kamoun W, Jain RK, Fukumura D, Xu L. PDGF-D improves drug delivery and efficacy via vascular normalization, but promotes lymphatic metastasis by activating CXCR4 in breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3638-48. PMID 21459800 DOI: 10.1158/1078-0432.Ccr-10-2456  0.494
2008 Naxerova K, Bult CJ, Peaston A, Fancher K, Knowles BB, Kasif S, Kohane IS. Analysis of gene expression in a developmental context emphasizes distinct biological leitmotifs in human cancers. Genome Biology. 9: R108. PMID 18611264 DOI: 10.1186/Gb-2008-9-7-R108  0.376
Low-probability matches (unlikely to be authored by this person)
2020 Reiter JG, Hung WT, Lee IH, Nagpal S, Giunta P, Degner S, Liu G, Wassenaar ECE, Jeck WR, Taylor MS, Farahani AA, Marble HD, Knott S, Kranenburg O, Lennerz JK, ... Naxerova K, et al. Lymph node metastases develop through a wider evolutionary bottleneck than distant metastases. Nature Genetics. PMID 32451459 DOI: 10.1038/S41588-020-0633-2  0.286
2024 Watson EV, Lee JJ, Gulhan DC, Melloni GEM, Venev SV, Magesh RY, Frederick A, Chiba K, Wooten EC, Naxerova K, Dekker J, Park PJ, Elledge SJ. Chromosome evolution screens recapitulate tissue-specific tumor aneuploidy patterns. Nature Genetics. PMID 38388848 DOI: 10.1038/s41588-024-01665-2  0.265
2021 Leong SP, Naxerova K, Keller L, Pantel K, Witte M. Molecular mechanisms of cancer metastasis via the lymphatic versus the blood vessels. Clinical & Experimental Metastasis. PMID 34767139 DOI: 10.1007/s10585-021-10120-z  0.262
2015 Dutta P, Sager HB, Stengel KR, Naxerova K, Courties G, Saez B, Silberstein L, Heidt T, Sebas M, Sun Y, Wojtkiewicz G, Feruglio PF, King K, Baker JN, van der Laan AM, et al. Myocardial Infarction Activates CCR2(+) Hematopoietic Stem and Progenitor Cells. Cell Stem Cell. 16: 477-87. PMID 25957903 DOI: 10.1016/J.Stem.2015.04.008  0.256
2007 Gorgun G, Philpot P, Naxerova K, Kohane I, Nadler L, Guinan E. Costimulatory Blockade (CSB) during Mixed Lymphocyte Reaction (MLR) Prevents IL27 Upregulation and Signalling. Blood. 110: 4878-4878. DOI: 10.1182/Blood.V110.11.4878.4878  0.254
2019 Hoyer FF, Naxerova K, Schloss MJ, Hulsmans M, Nair AV, Dutta P, Calcagno DM, Herisson F, Anzai A, Sun Y, Wojtkiewicz G, Rohde D, Frodermann V, Vandoorne K, Courties G, et al. Tissue-Specific Macrophage Responses to Remote Injury Impact the Outcome of Subsequent Local Immune Challenge. Immunity. PMID 31732166 DOI: 10.1016/J.Immuni.2019.10.010  0.253
2018 Hulsmans M, Sager HB, Roh JD, Valero-Muñoz M, Houstis NE, Iwamoto Y, Sun Y, Wilson RM, Wojtkiewicz G, Tricot B, Osborne MT, Hung J, Vinegoni C, Naxerova K, Sosnovik DE, et al. Cardiac macrophages promote diastolic dysfunction. The Journal of Experimental Medicine. PMID 29339450 DOI: 10.1084/Jem.20171274  0.25
2020 Hoyer FF, Zhang X, Coppin E, Vasamsetti SB, Modugu G, Schloss MJ, Rohde D, McAlpine CS, Iwamoto Y, Libby P, Naxerova K, Swirski FK, Dutta P, Nahrendorf M. Bone Marrow Endothelial Cells Regulate Myelopoiesis in Diabetes. Circulation. PMID 32316750 DOI: 10.1161/Circulationaha.120.046038  0.249
2019 Frodermann V, Rohde D, Courties G, Severe N, Schloss MJ, Amatullah H, McAlpine CS, Cremer S, Hoyer FF, Ji F, van Koeverden ID, Herisson F, Honold L, Masson GS, Zhang S, ... ... Naxerova K, et al. Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells. Nature Medicine. PMID 31700184 DOI: 10.1038/S41591-019-0633-X  0.248
2019 Naxerova K. Interrogating CD8+ T cell reactivity on a genome-wide scale Science Translational Medicine. 11: eaaz0302. DOI: 10.1126/Scitranslmed.Aaz0302  0.24
2017 Hulsmans M, Clauss S, Xiao L, Aguirre AD, King KR, Hanley A, Hucker WJ, Wülfers EM, Seemann G, Courties G, Iwamoto Y, Sun Y, Savol AJ, Sager HB, Lavine KJ, ... ... Naxerova K, et al. Macrophages Facilitate Electrical Conduction in the Heart. Cell. 169: 510-522.e20. PMID 28431249 DOI: 10.1016/J.Cell.2017.03.050  0.236
2019 Naxerova K. A new function for polycomb in immune evasion Science Translational Medicine. 11: eaaz3718. DOI: 10.1126/Scitranslmed.Aaz3718  0.232
2007 Otu HH, Naxerova K, Ho K, Can H, Nesbitt N, Libermann TA, Karp SJ. Restoration of liver mass after injury requires proliferative and not embryonic transcriptional patterns. The Journal of Biological Chemistry. 282: 11197-204. PMID 17227769 DOI: 10.1074/Jbc.M608441200  0.22
2020 Naxerova K. A spring-like renewal in the lungs Science Translational Medicine. 12: eaba9020. DOI: 10.1126/Scitranslmed.Aba9020  0.219
2019 Naxerova K. Somatic mutations are improving their bad rap Science Translational Medicine. 11: eaax4871. DOI: 10.1126/Scitranslmed.Aax4871  0.212
2021 Zhang Y, Kohrn BF, Yang M, Nachmanson D, Soong TR, Lee IH, Tao Y, Clevers H, Swisher EM, Brentnall TA, Loeb LA, Kennedy SR, Salk JJ, Naxerova K, Risques RA. PolyG-DS: An ultrasensitive polyguanine tract-profiling method to detect clonal expansions and trace cell lineage. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34330826 DOI: 10.1073/pnas.2023373118  0.209
2020 Naxerova K. Clonal competition in a confined space. Nature Genetics. 52: 553-554. PMID 32424354 DOI: 10.1038/S41588-020-0638-X  0.203
2023 Küçükköse E, Laoukili J, Gorelick AN, Degner S, Lacle M, van den Bent L, Peters NA, Verheem A, Hung WT, Frenkel NC, Wassenaar E, Lansu N, Lenos KJ, Vermeulen L, Koopman M, ... ... Naxerova K, et al. Lymphatic invasion of plakoglobin-dependent tumor cell clusters drives formation of polyclonal lung metastases in colon cancer. Gastroenterology. PMID 36906044 DOI: 10.1053/j.gastro.2023.02.047  0.198
2022 Cheek DM, Naxerova K. Mapping the long road to cancer. Cell. 185: 939-940. PMID 35263624 DOI: 10.1016/j.cell.2022.02.020  0.191
2019 Naxerova K. From micrographs to microsatellites in one bold step Science Translational Medicine. 11: eaax9570. DOI: 10.1126/Scitranslmed.Aax9570  0.181
2022 Schloss MJ, Hulsmans M, Rohde D, Lee IH, Severe N, Foy BH, Pulous FE, Zhang S, Kokkaliaris KD, Frodermann V, Courties G, Yang C, Iwamoto Y, Knudsen AS, McAlpine CS, ... ... Naxerova K, et al. B lymphocyte-derived acetylcholine limits steady-state and emergency hematopoiesis. Nature Immunology. PMID 35352063 DOI: 10.1038/s41590-022-01165-7  0.15
2021 Heyde A, Rohde D, McAlpine CS, Zhang S, Hoyer FF, Gerold JM, Cheek D, Iwamoto Y, Schloss MJ, Vandoorne K, Iborra-Egea O, Muñoz-Guijosa C, Bayes-Genis A, Reiter JG, Craig M, ... ... Naxerova K, et al. Increased stem cell proliferation in atherosclerosis accelerates clonal hematopoiesis. Cell. PMID 33636128 DOI: 10.1016/j.cell.2021.01.049  0.128
2023 Hulsmans M, Schloss MJ, Lee IH, Bapat A, Iwamoto Y, Vinegoni C, Paccalet A, Yamazoe M, Grune J, Pabel S, Momin N, Seung H, Kumowski N, Pulous FE, Keller D, ... ... Naxerova K, et al. Recruited macrophages elicit atrial fibrillation. Science (New York, N.Y.). 381: 231-239. PMID 37440641 DOI: 10.1126/science.abq3061  0.123
2021 Naxerova K, Di Stefano B, Makofske JL, Watson EV, de Kort MA, Martin TD, Dezfulian M, Ricken D, Wooten EC, Kuroda MI, Hochedlinger K, Elledge SJ. Integrated loss- and gain-of-function screens define a core network governing human embryonic stem cell behavior. Genes & Development. PMID 34711655 DOI: 10.1101/gad.349048.121  0.119
2021 Rohde D, Vandoorne K, Lee IH, Grune J, Zhang S, McAlpine CS, Schloss MJ, Nayar R, Courties G, Frodermann V, Wojtkiewicz G, Honold L, Chen Q, Schmidt S, Iwamoto Y, ... ... Naxerova K, et al. Bone marrow endothelial dysfunction promotes myeloid cell expansion in cardiovascular disease. Nature Cardiovascular Research. 1: 28-44. PMID 35747128 DOI: 10.1038/s44161-021-00002-8  0.101
2023 Zhang S, Paccalet A, Rohde D, Cremer S, Hulsmans M, Lee IH, Mentkowski K, Grune J, Schloss MJ, Honold L, Iwamoto Y, Zheng Y, Bredella MA, Buckless C, Ghoshhajra B, ... ... Naxerova K, et al. Bone marrow adipocytes fuel emergency hematopoiesis after myocardial infarction. Nature Cardiovascular Research. 2: 1277-1290. PMID 38344689 DOI: 10.1038/s44161-023-00388-7  0.092
2023 Janizek JD, Dincer AB, Celik S, Chen H, Chen W, Naxerova K, Lee SI. Uncovering expression signatures of synergistic drug responses via ensembles of explainable machine-learning models. Nature Biomedical Engineering. PMID 37127711 DOI: 10.1038/s41551-023-01034-0  0.088
2021 Naxerova K. Mutation fingerprints encode cellular histories. Nature. PMID 34433973 DOI: 10.1038/d41586-021-02269-0  0.052
2023 Ordulu Z, Giunta P, Hung WT, Hung YP, Simon J, Fintelmann FJ, Lennerz JK, Naxerova K, Cote GM. Sensitivity to ALK-Directed Therapy in Osteosarcoma With an Acquired Rearrangement. Jco Precision Oncology. 7: e2300287. PMID 38096470 DOI: 10.1200/PO.23.00287  0.046
2022 Schloss MJ, Hulsmans M, Rohde D, Lee IH, Severe N, Foy BH, Pulous FE, Zhang S, Kokkaliaris KD, Frodermann V, Courties G, Yang C, Iwamoto Y, Knudsen AS, McAlpine CS, ... ... Naxerova K, et al. Author Correction: B lymphocyte-derived acetylcholine limits steady-state and emergency hematopoiesis. Nature Immunology. PMID 35705799 DOI: 10.1038/s41590-022-01266-3  0.042
2008 Gorgun G, Philpot P, Naxerova K, Kohane I, Nadler L, Guinan E. 10: Costimulatory Blockade (CSB) During Mixed Lymphocyte Reaction (MLR) Prevents IL27 Upregulation and Signalling Biology of Blood and Marrow Transplantation. 14: 6. DOI: 10.1016/j.bbmt.2007.12.018  0.04
2022 McAlpine CS, Kiss MG, Zuraikat FM, Cheek D, Schiroli G, Amatullah H, Huynh P, Bhatti MZ, Wong LP, Yates AG, Poller WC, Mindur JE, Chan CT, Janssen H, Downey J, ... ... Naxerova K, et al. Sleep exerts lasting effects on hematopoietic stem cell function and diversity. The Journal of Experimental Medicine. 219. PMID 36129517 DOI: 10.1084/jem.20220081  0.033
2022 Gorelick AN, Naxerova K. Mutational clocks tick differently across species. Nature. 604: 435-436. PMID 35418556 DOI: 10.1038/d41586-022-00976-w  0.032
2015 Naxerova K, Elledge SJ. Taking the brakes off telomerase Elife. 4: 1-3. DOI: 10.7554/eLife.09519  0.032
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