Year |
Citation |
Score |
2023 |
Bruun DA, Ma B, Chen YJ, Wu CY, Aleman M, Zolkowska D, Smiley-Jewell SM, Rogawski MA, Lein PJ. Tolerability and pharmacokinetics of intravenous allopregnanolone with and without midazolam pretreatment in two healthy dogs. Epilepsia Open. PMID 36919379 DOI: 10.1002/epi4.12723 |
0.659 |
|
2021 |
Vuu I, Patterson EE, Wu CY, Zolkowska D, Leppik IE, Rogawski MA, Worrell GA, Kremen V, Cloyd JC, Coles LD. Intravenous and Intramuscular Allopregnanolone for Early Treatment of Status Epilepticus: Pharmacokinetics, Pharmacodynamics, and Safety in Dogs. The Journal of Pharmacology and Experimental Therapeutics. PMID 34862270 DOI: 10.1124/jpet.121.000736 |
0.688 |
|
2021 |
Calsbeek JJ, González EA, Boosalis CA, Zolkowska D, Bruun DA, Rowland DJ, Saito NH, Harvey DJ, Chaudhari AJ, Rogawski MA, Garbow JR, Lein PJ. Strain differences in the extent of brain injury in mice after tetramethylenedisulfotetramine-induced status epilepticus. Neurotoxicology. PMID 34478772 DOI: 10.1016/j.neuro.2021.08.011 |
0.679 |
|
2021 |
Zolkowska D, Dhir A, Rogawski MA. Perampanel, a potent AMPA receptor antagonist, protects against tetramethylenedisulfotetramine-induced seizures and lethality in mice: comparison with diazepam. Archives of Toxicology. PMID 33914090 DOI: 10.1007/s00204-021-03053-9 |
0.794 |
|
2021 |
Zolkowska D, Wu CY, Rogawski MA. Intranasal Allopregnanolone Confers Rapid Seizure Protection: Evidence for Direct Nose-to-Brain Delivery. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 33405197 DOI: 10.1007/s13311-020-00985-5 |
0.74 |
|
2020 |
Dhir A, Bruun DA, Guignet M, Tsai YH, González E, Calsbeek J, Vu J, Saito N, Tancredi DJ, Harvey DJ, Lein PJ, Rogawski MA. Allopregnanolone and perampanel as adjuncts to midazolam for treating diisopropylfluorophosphate-induced status epilepticus in rats. Annals of the New York Academy of Sciences. PMID 32915470 DOI: 10.1111/Nyas.14479 |
0.666 |
|
2020 |
González EA, Rindy AC, Guignet MA, Calsbeek JJ, Bruun DA, Dhir A, Andrew P, Saito N, Rowland DJ, Harvey DJ, Rogawski MA, Lein PJ. The chemical convulsant diisopropylfluorophosphate (DFP) causes persistent neuropathology in adult male rats independent of seizure activity. Archives of Toxicology. PMID 32303805 DOI: 10.1007/S00204-020-02747-W |
0.637 |
|
2020 |
Sills GJ, Rogawski MA. Mechanisms of action of currently used antiseizure drugs. Neuropharmacology. 168: 107966. PMID 32120063 DOI: 10.1016/j.neuropharm.2020.107966 |
0.421 |
|
2019 |
Rogawski MA, Heller AH. Diazepam buccal film for the treatment of acute seizures. Epilepsy & Behavior : E&B. 106537. PMID 31699662 DOI: 10.1016/j.yebeh.2019.106537 |
0.42 |
|
2019 |
Rogawski MA. Reduced efficacy and risk of seizure aggravation when cannabidiol is used without clobazam. Epilepsy & Behavior : E&B. 106506. PMID 31526646 DOI: 10.1016/j.yebeh.2019.106506 |
0.384 |
|
2019 |
Guignet M, Dhakal K, Flannery BM, Hobson BA, Zolkowska D, Dhir A, Bruun DA, Li S, Wahab A, Harvey DJ, Silverman JL, Rogawski MA, Lein PJ. Persistent behavior deficits, neuroinflammation, and oxidative stress in a rat model of acute organophosphate intoxication. Neurobiology of Disease. PMID 30905768 DOI: 10.1016/J.Nbd.2019.03.019 |
0.754 |
|
2019 |
Vuu I, Patterson E, Wu C, Zolkowska D, Leppik I, Rogawski M, Worrell G, Kremen V, Cloyd J, Coles L. Allopregnanolone Pharmacokinetic-Pharmacodynamic Modeling and Simulations in Dogs with Naturally-Occurring Epilepsy Epilepsy & Behavior. 101: 106805. DOI: 10.1016/J.Yebeh.2019.08.080 |
0.7 |
|
2019 |
Zolkowska D, Rogawski MA. Efficacy of Intranasal Allopregnanolone in a Mouse Seizure Model Epilepsy & Behavior. 101: 106738. DOI: 10.1016/J.Yebeh.2019.08.013 |
0.733 |
|
2018 |
Dhir A, Rogawski MA. Determination of minimal steady-state plasma level of diazepam causing seizure threshold elevation in rats. Epilepsia. PMID 29682729 DOI: 10.1111/Epi.14069 |
0.624 |
|
2018 |
Zolkowska D, Wu CY, Rogawski MA. Intramuscular allopregnanolone and ganaxolone in a mouse model of treatment-resistant status epilepticus. Epilepsia. PMID 29453777 DOI: 10.1111/Epi.13999 |
0.727 |
|
2017 |
Klein P, Dingledine R, Aronica E, Bernard C, Blümcke I, Boison D, Brodie MJ, Brooks-Kayal AR, Engel J, Forcelli PA, Hirsch LJ, Kaminski RM, Klitgaard H, Kobow K, Lowenstein DH, ... ... Rogawski MA, et al. Commonalities in epileptogenic processes from different acute brain insults: Do they translate? Epilepsia. PMID 29247482 DOI: 10.1111/Epi.13965 |
0.604 |
|
2017 |
Chen CY, Di Lucente J, Lin YC, Lien CC, Rogawski MA, Maezawa I, Jin LW. Defective GABAergic neurotransmission in the nucleus tractus solitarius in Mecp2-null mice, a model of Rett syndrome. Neurobiology of Disease. PMID 28927958 DOI: 10.1016/J.Nbd.2017.09.006 |
0.375 |
|
2017 |
Vaitkevicius H, Husain AM, Rosenthal ES, Rosand J, Bobb W, Reddy K, Rogawski MA, Cole AJ. First-in-man allopregnanolone use in super-refractory status epilepticus. Annals of Clinical and Translational Neurology. 4: 411-414. PMID 28589168 DOI: 10.1002/Acn3.408 |
0.341 |
|
2017 |
Dingledine R, Coulter DA, Fritsch B, Gorter JA, Lelutiu N, McNamara J, Nadler JV, Pitkänen A, Rogawski MA, Skene P, Sloviter RS, Wang Y, Wadman WJ, Wasterlain C, Roopra A. Transcriptional profile of hippocampal dentate granule cells in four rat epilepsy models. Scientific Data. 4: 170061. PMID 28485718 DOI: 10.1038/Sdata.2017.61 |
0.629 |
|
2017 |
Mousavi Nik A, Pressly B, Singh V, Antrobus S, Hulsizer S, Rogawski MA, Wulff H, Pessah IN. Rapid Throughput Analysis of GABAA Receptor Subtype Modulators and Blockers Using DiSBAC1(3) Membrane Potential Red Dye. Molecular Pharmacology. PMID 28428226 DOI: 10.1124/Mol.117.108563 |
0.346 |
|
2017 |
Lévesque M, Herrington R, Leclerc L, Rogawski MA, Avoli M. Allopregnanolone decreases interictal spiking and fast ripples in an animal model of mesial temporal lobe epilepsy. Neuropharmacology. PMID 28416442 DOI: 10.1016/j.neuropharm.2017.04.020 |
0.43 |
|
2016 |
Ciarlone SL, Wang X, Rogawski MA, Weeber EJ. Effects of the synthetic neurosteroid ganaxolone on seizure activity and behavioral deficits in an Angelman syndrome mouse model. Neuropharmacology. PMID 27986596 DOI: 10.1016/j.neuropharm.2016.12.009 |
0.392 |
|
2016 |
Pessah IN, Rogawski MA, Tancredi DJ, Wulff H, Zolkowska D, Bruun DA, Hammock BD, Lein PJ. Models to identify treatments for the acute and persistent effects of seizure-inducing chemical threat agents. Annals of the New York Academy of Sciences. PMID 27467073 DOI: 10.1111/Nyas.13137 |
0.737 |
|
2016 |
Rogawski MA, Löscher W, Rho JM. Mechanisms of Action of Antiseizure Drugs and the Ketogenic Diet. Cold Spring Harbor Perspectives in Medicine. PMID 26801895 DOI: 10.1101/cshperspect.a022780 |
0.65 |
|
2015 |
Kazdoba TM, Hagerman RJ, Zolkowska D, Rogawski MA, Crawley JN. Evaluation of the neuroactive steroid ganaxolone on social and repetitive behaviors in the BTBR mouse model of autism. Psychopharmacology. PMID 26525567 DOI: 10.1007/S00213-015-4115-7 |
0.686 |
|
2015 |
Desai R, Savechenkov PY, Zolkowska D, Ge RL, Rogawski MA, Bruzik KS, Forman SA, Raines DE, Miller KW. Contrasting actions of a convulsant barbiturate and its anti-convulsant enantiomer on the α1β3γ2L GABAA receptor account for their in vivo effects. The Journal of Physiology. PMID 26378885 DOI: 10.1113/Jp270971 |
0.695 |
|
2015 |
Irwin RW, Solinsky CM, Loya CM, Salituro FG, Rodgers KE, Bauer G, Rogawski MA, Brinton RD. Allopregnanolone preclinical acute pharmacokinetic and pharmacodynamic studies to predict tolerability and efficacy for Alzheimer's disease. Plos One. 10: e0128313. PMID 26039057 DOI: 10.1371/Journal.Pone.0128313 |
0.317 |
|
2015 |
Bruun DA, Cao Z, Inceoglu B, Vito ST, Austin AT, Hulsizer S, Hammock BD, Tancredi DJ, Rogawski MA, Pessah IN, Lein PJ. Combined treatment with diazepam and allopregnanolone reverses tetramethylenedisulfotetramine (TETS)-induced calcium dysregulation in cultured neurons and protects TETS-intoxicated mice against lethal seizures. Neuropharmacology. 95: 332-42. PMID 25882826 DOI: 10.1016/J.Neuropharm.2015.03.035 |
0.444 |
|
2015 |
Rogawski MA, Tofighy A, White HS, Matagne A, Wolff C. Current understanding of the mechanism of action of the antiepileptic drug lacosamide. Epilepsy Research. 110: 189-205. PMID 25616473 DOI: 10.1016/J.Eplepsyres.2014.11.021 |
0.485 |
|
2015 |
Coleman N, Nguyen HM, Cao Z, Brown BM, Jenkins DP, Zolkowska D, Chen YJ, Tanaka BS, Goldin AL, Rogawski MA, Pessah IN, Wulff H. The riluzole derivative 2-amino-6-trifluoromethylthio-benzothiazole (SKA-19), a mixed KCa2 activator and NaV blocker, is a potent novel anticonvulsant. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 12: 234-49. PMID 25256961 DOI: 10.1007/S13311-014-0305-Y |
0.746 |
|
2014 |
Vito ST, Austin AT, Banks CN, Inceoglu B, Bruun DA, Zolkowska D, Tancredi DJ, Rogawski MA, Hammock BD, Lein PJ. Post-exposure administration of diazepam combined with soluble epoxide hydrolase inhibition stops seizures and modulates neuroinflammation in a murine model of acute TETS intoxication. Toxicology and Applied Pharmacology. 281: 185-94. PMID 25448683 DOI: 10.1016/J.Taap.2014.10.001 |
0.769 |
|
2014 |
Broomall E, Natale JE, Grimason M, Goldstein J, Smith CM, Chang C, Kanes S, Rogawski MA, Wainwright MS. Pediatric super-refractory status epilepticus treated with allopregnanolone. Annals of Neurology. 76: 911-5. PMID 25363147 DOI: 10.1002/Ana.24295 |
0.405 |
|
2014 |
Chen CY, Matt L, Hell JW, Rogawski MA. Perampanel inhibition of AMPA receptor currents in cultured hippocampal neurons. Plos One. 9: e108021. PMID 25229608 DOI: 10.1371/journal.pone.0108021 |
0.431 |
|
2014 |
Fritsch B, Reis J, Gasior M, Kaminski RM, Rogawski MA. Role of GluK1 kainate receptors in seizures, epileptic discharges, and epileptogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 5765-75. PMID 24760837 DOI: 10.1523/Jneurosci.5307-13.2014 |
0.81 |
|
2014 |
Zolkowska D, Dhir A, Krishnan K, Covey DF, Rogawski MA. Anticonvulsant potencies of the enantiomers of the neurosteroids androsterone and etiocholanolone exceed those of the natural forms. Psychopharmacology. 231: 3325-32. PMID 24705905 DOI: 10.1007/S00213-014-3546-X |
0.709 |
|
2014 |
Kaminski RM, Rogawski MA, Klitgaard H. The potential of antiseizure drugs and agents that act on novel molecular targets as antiepileptogenic treatments. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 11: 385-400. PMID 24671870 DOI: 10.1007/s13311-014-0266-1 |
0.609 |
|
2013 |
Inceoglu B, Zolkowska D, Yoo HJ, Wagner KM, Yang J, Hackett E, Hwang SH, Lee KS, Rogawski MA, Morisseau C, Hammock BD. Epoxy fatty acids and inhibition of the soluble epoxide hydrolase selectively modulate GABA mediated neurotransmission to delay onset of seizures. Plos One. 8: e80922. PMID 24349022 DOI: 10.1371/Journal.Pone.0080922 |
0.745 |
|
2013 |
Rogawski MA, Loya CM, Reddy K, Zolkowska D, Lossin C. Neuroactive steroids for the treatment of status epilepticus. Epilepsia. 54: 93-8. PMID 24001085 DOI: 10.1111/Epi.12289 |
0.758 |
|
2013 |
Wilcox KS, Dixon-Salazar T, Sills GJ, Ben-Menachem E, White HS, Porter RJ, Dichter MA, Moshé SL, Noebels JL, Privitera MD, Rogawski MA. Issues related to development of new antiseizure treatments. Epilepsia. 54: 24-34. PMID 23909851 DOI: 10.1111/Epi.12296 |
0.393 |
|
2013 |
Galanopoulou AS, Kokaia M, Loeb JA, Nehlig A, Pitkänen A, Rogawski MA, Staley KJ, Whittemore VH, Dudek FE. Epilepsy therapy development: technical and methodologic issues in studies with animal models. Epilepsia. 54: 13-23. PMID 23909850 DOI: 10.1111/Epi.12295 |
0.41 |
|
2013 |
Bröer S, Zolkowska D, Gernert M, Rogawski MA. Proconvulsant actions of intrahippocampal botulinum neurotoxin B in the rat. Neuroscience. 252: 253-61. PMID 23906638 DOI: 10.1016/J.Neuroscience.2013.07.050 |
0.732 |
|
2013 |
Dhir A, Zolkowska D, Rogawski MA. Seizure protection by intrapulmonary delivery of midazolam in mice. Neuropharmacology. 73: 425-31. PMID 23774136 DOI: 10.1016/J.Neuropharm.2013.06.002 |
0.792 |
|
2013 |
Gasior M, Tang R, Rogawski MA. Long-lasting attenuation of amygdala-kindled seizures after convection-enhanced delivery of botulinum neurotoxins a and B into the amygdala in rats. The Journal of Pharmacology and Experimental Therapeutics. 346: 528-34. PMID 23772062 DOI: 10.1124/jpet.113.205070 |
0.61 |
|
2013 |
Rogawski MA. The intrinsic severity hypothesis of pharmacoresistance to antiepileptic drugs. Epilepsia. 54: 33-40. PMID 23646969 DOI: 10.1111/epi.12182 |
0.392 |
|
2013 |
Rogawski MA, Hanada T. Preclinical pharmacology of perampanel, a selective non-competitive AMPA receptor antagonist. Acta Neurologica Scandinavica. Supplementum. 19-24. PMID 23480152 DOI: 10.1111/ane.12100 |
0.435 |
|
2013 |
Rogawski MA. AMPA receptors as a molecular target in epilepsy therapy. Acta Neurologica Scandinavica. Supplementum. 9-18. PMID 23480151 DOI: 10.1111/ane.12099 |
0.457 |
|
2013 |
Devinsky O, Vezzani A, Najjar S, De Lanerolle NC, Rogawski MA. Glia and epilepsy: excitability and inflammation. Trends in Neurosciences. 36: 174-84. PMID 23298414 DOI: 10.1016/j.tins.2012.11.008 |
0.412 |
|
2012 |
Löscher W, Rogawski MA. How theories evolved concerning the mechanism of action of barbiturates. Epilepsia. 53: 12-25. PMID 23205959 DOI: 10.1111/epi.12025 |
0.413 |
|
2012 |
Porter RJ, Dhir A, Macdonald RL, Rogawski MA. Mechanisms of action of antiseizure drugs. Handbook of Clinical Neurology. 108: 663-81. PMID 22939059 DOI: 10.1016/B978-0-444-52899-5.00021-6 |
0.59 |
|
2012 |
Cao Z, Hammock BD, McCoy M, Rogawski MA, Lein PJ, Pessah IN. Tetramethylenedisulfotetramine alters Ca²⺠dynamics in cultured hippocampal neurons: mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation. Toxicological Sciences : An Official Journal of the Society of Toxicology. 130: 362-72. PMID 22889812 DOI: 10.1093/Toxsci/Kfs244 |
0.382 |
|
2012 |
French JA, Krauss GL, Biton V, Squillacote D, Yang H, Laurenza A, Kumar D, Rogawski MA. Adjunctive perampanel for refractory partial-onset seizures: randomized phase III study 304. Neurology. 79: 589-96. PMID 22843280 DOI: 10.1212/WNL.0b013e3182635735 |
0.419 |
|
2012 |
Lossin C, Shi X, Rogawski MA, Hirose S. Compromised function in the Na(v)1.2 Dravet syndrome mutation R1312T. Neurobiology of Disease. 47: 378-84. PMID 22677033 DOI: 10.1016/j.nbd.2012.05.017 |
0.352 |
|
2012 |
Cao Z, Hulsizer S, Tassone F, Tang HT, Hagerman RJ, Rogawski MA, Hagerman PJ, Pessah IN. Clustered burst firing in FMR1 premutation hippocampal neurons: amelioration with allopregnanolone. Human Molecular Genetics. 21: 2923-35. PMID 22466801 DOI: 10.1093/Hmg/Dds118 |
0.338 |
|
2012 |
Dhir A, Lossin C, Rogawski MA. Propofol hemisuccinate suppresses cortical spreading depression. Neuroscience Letters. 514: 67-70. PMID 22390898 DOI: 10.1016/J.Neulet.2012.02.058 |
0.57 |
|
2012 |
Zolkowska D, Banks CN, Dhir A, Inceoglu B, Sanborn JR, McCoy MR, Bruun DA, Hammock BD, Lein PJ, Rogawski MA. Characterization of seizures induced by acute and repeated exposure to tetramethylenedisulfotetramine. The Journal of Pharmacology and Experimental Therapeutics. 341: 435-46. PMID 22328574 DOI: 10.1124/Jpet.111.190579 |
0.796 |
|
2012 |
Dhir A, Rogawski MA. Role of neurosteroids in the anticonvulsant activity of midazolam. British Journal of Pharmacology. 165: 2684-91. PMID 22014182 DOI: 10.1111/J.1476-5381.2011.01733.X |
0.633 |
|
2011 |
Rogawski MA. Revisiting AMPA receptors as an antiepileptic drug target. Epilepsy Currents / American Epilepsy Society. 11: 56-63. PMID 21686307 DOI: 10.5698/1535-7511-11.2.56 |
0.423 |
|
2011 |
Kaminski RM, Rogawski MA. 11β-Hydroxylase inhibitors protect against seizures in mice by increasing endogenous neurosteroid synthesis. Neuropharmacology. 61: 133-7. PMID 21458468 DOI: 10.1016/j.neuropharm.2011.03.019 |
0.634 |
|
2011 |
Dhir A, Zolkowska D, Murphy RB, Rogawski MA. Seizure protection by intrapulmonary delivery of propofol hemisuccinate. The Journal of Pharmacology and Experimental Therapeutics. 336: 215-22. PMID 20837991 DOI: 10.1124/Jpet.110.173591 |
0.782 |
|
2010 |
Reddy DS, Rogawski MA. Neurosteroids as endogenous regulators of seizure susceptibility and use in the treatment of epilepsy. Epilepsia. 51: 84. PMID 25147407 DOI: 10.1111/j.1528-1167.2010.02870.x |
0.619 |
|
2010 |
Noebels JL, Avoli M, Rogawski M, Olsen R, Delgado-Escueta AV. "Jasper's Basic Mechanisms of the Epilepsies" Workshop. Epilepsia. 51: 1-5. PMID 21208201 DOI: 10.1111/J.1528-1167.2010.02792.X |
0.412 |
|
2010 |
Rogawski MA. Neurosteroids on the epilepsy chessboard-keeping seizures in check. Epilepsy Currents / American Epilepsy Society. 10: 161-3. PMID 21157546 DOI: 10.1111/j.1535-7511.2010.01388.x |
0.457 |
|
2010 |
Gasior M, Yankura J, Hartman AL, French A, Rogawski MA. Anticonvulsant and proconvulsant actions of 2-deoxy-D-glucose. Epilepsia. 51: 1385-94. PMID 20491877 DOI: 10.1111/J.1528-1167.2010.02593.X |
0.733 |
|
2010 |
Reddy DS, Rogawski MA. Ganaxolone suppression of behavioral and electrographic seizures in the mouse amygdala kindling model. Epilepsy Research. 89: 254-60. PMID 20172694 DOI: 10.1016/j.eplepsyres.2010.01.009 |
0.641 |
|
2010 |
Fritsch B, Stott JJ, Joelle Donofrio J, Rogawski MA. Treatment of early and late kainic acid-induced status epilepticus with the noncompetitive AMPA receptor antagonist GYKI 52466. Epilepsia. 51: 108-17. PMID 19682025 DOI: 10.1111/J.1528-1167.2009.02205.X |
0.806 |
|
2010 |
Rogawski MA. Migraine and epilepsy: Shared mechanisms? Epilepsia. 51: 80. DOI: 10.1111/j.1528-1167.2010.02866.x |
0.384 |
|
2009 |
Runyon SP, Orr M, Navarro HA, Kepler JA, Rogawski MA, Kaminski RM, Cook CE. 17beta-Nitro-5alpha-androstan-3alpha-ol and its 3beta-methyl derivative: neurosteroid analogs with potent anticonvulsant and anxiolytic activities. European Journal of Pharmacology. 617: 68-73. PMID 19577558 DOI: 10.1016/J.Ejphar.2009.06.052 |
0.562 |
|
2009 |
Fritsch B, Qashu F, Figueiredo TH, Aroniadou-Anderjaska V, Rogawski MA, Braga MF. Pathological alterations in GABAergic interneurons and reduced tonic inhibition in the basolateral amygdala during epileptogenesis. Neuroscience. 163: 415-29. PMID 19540312 DOI: 10.1016/J.Neuroscience.2009.06.034 |
0.708 |
|
2009 |
Braga MF, Aroniadou-Anderjaska V, Li H, Rogawski MA. Topiramate reduces excitability in the basolateral amygdala by selectively inhibiting GluK1 (GluR5) kainate receptors on interneurons and positively modulating GABAA receptors on principal neurons. The Journal of Pharmacology and Experimental Therapeutics. 330: 558-66. PMID 19417176 DOI: 10.1124/Jpet.109.153908 |
0.448 |
|
2009 |
Reddy DS, Rogawski MA. Neurosteroid replacement therapy for catamenial epilepsy. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 6: 392-401. PMID 19332335 DOI: 10.1016/j.nurt.2009.01.006 |
0.652 |
|
2009 |
Rogawski MA. Convection-enhanced delivery in the treatment of epilepsy. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 6: 344-51. PMID 19332329 DOI: 10.1016/j.nurt.2009.01.017 |
0.435 |
|
2009 |
Rogawski MA, Holmes GL. Nontraditional epilepsy treatment approaches. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 6: 213-7. PMID 19332312 DOI: 10.1016/J.Nurt.2009.02.002 |
0.344 |
|
2009 |
Biagini G, Longo D, Baldelli E, Zoli M, Rogawski MA, Bertazzoni G, Avoli M. Neurosteroids and epileptogenesis in the pilocarpine model: evidence for a relationship between P450scc induction and length of the latent period. Epilepsia. 50: 53-8. PMID 19125849 DOI: 10.1111/J.1528-1167.2008.01971.X |
0.462 |
|
2008 |
Rogawski MA, Johnson MR. Intrinsic severity as a determinant of antiepileptic drug refractoriness. Epilepsy Currents / American Epilepsy Society. 8: 127-30. PMID 18852835 DOI: 10.1111/j.1535-7511.2008.00272.x |
0.35 |
|
2008 |
Rogawski MA, Bazil CW. New molecular targets for antiepileptic drugs: alpha(2)delta, SV2A, and K(v)7/KCNQ/M potassium channels. Current Neurology and Neuroscience Reports. 8: 345-52. PMID 18590620 DOI: 10.1007/s11910-008-0053-7 |
0.31 |
|
2008 |
Rogawski MA. Brivaracetam: a rational drug discovery success story. British Journal of Pharmacology. 154: 1555-7. PMID 18552880 DOI: 10.1038/bjp.2008.221 |
0.437 |
|
2008 |
Rogawski MA. Common pathophysiologic mechanisms in migraine and epilepsy. Archives of Neurology. 65: 709-14. PMID 18541791 DOI: 10.1001/archneur.65.6.709 |
0.452 |
|
2008 |
Gasior M, Hartman AL, Rogawski MA. The anticonvulsant activity of acetone does not depend upon its metabolites. Epilepsia. 49: 936-7. PMID 18454785 DOI: 10.1111/J.1528-1167.2007.01518_3.X |
0.67 |
|
2008 |
Shaltiel G, Maeng S, Malkesman O, Pearson B, Schloesser RJ, Tragon T, Rogawski M, Gasior M, Luckenbaugh D, Chen G, Manji HK. Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania. Molecular Psychiatry. 13: 858-72. PMID 18332879 DOI: 10.1038/Mp.2008.20 |
0.545 |
|
2008 |
Hartman AL, Lyle M, Rogawski MA, Gasior M. Efficacy of the ketogenic diet in the 6-Hz seizure test. Epilepsia. 49: 334-9. PMID 18070095 DOI: 10.1111/J.1528-1167.2007.01430.X |
0.705 |
|
2008 |
Rogawski MA. Common Mechanisms in Migraine and Epilepsy: A Comment—Reply Jama Neurology. 65: 1546-1547. DOI: 10.1001/Archneur.65.11.1546-C |
0.392 |
|
2007 |
Dudek FE, Rogawski MA. Calcium currents burst back: a possible role for dendrites in epileptogenesis. Epilepsy Currents / American Epilepsy Society. 7: 140-1. PMID 17998977 DOI: 10.1111/j.1535-7511.2007.00205.x |
0.332 |
|
2007 |
Gasior M, White NA, Rogawski MA. Prolonged attenuation of amygdala-kindled seizure measures in rats by convection-enhanced delivery of the N-type calcium channel antagonists omega-conotoxin GVIA and omega-conotoxin MVIIA. The Journal of Pharmacology and Experimental Therapeutics. 323: 458-68. PMID 17717191 DOI: 10.1124/jpet.107.125047 |
0.619 |
|
2007 |
Hartman AL, Gasior M, Vining EP, Rogawski MA. The neuropharmacology of the ketogenic diet. Pediatric Neurology. 36: 281-92. PMID 17509459 DOI: 10.1016/J.Pediatrneurol.2007.02.008 |
0.725 |
|
2007 |
Rho JM, Rogawski MA. The ketogenic diet: stoking the powerhouse of the cell. Epilepsy Currents / American Epilepsy Society. 7: 58-60. PMID 17505556 DOI: 10.1111/j.1535-7511.2007.00170.x |
0.495 |
|
2007 |
Gasior M, French A, Joy MT, Tang RS, Hartman AL, Rogawski MA. The anticonvulsant activity of acetone, the major ketone body in the ketogenic diet, is not dependent on its metabolites acetol, 1,2-propanediol, methylglyoxal, or pyruvic acid. Epilepsia. 48: 793-800. PMID 17386058 DOI: 10.1111/J.1528-1167.2007.01026.X |
0.741 |
|
2007 |
Meldrum BS, Rogawski MA. Molecular targets for antiepileptic drug development. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 4: 18-61. PMID 17199015 DOI: 10.1016/j.nurt.2006.11.010 |
0.565 |
|
2007 |
KAMINSKI R, RUNYON S, MARINI H, ROGAWSKI M. Poster Abstract #7: Anticonvulsant Effects of a Synthetic Progestin, Norethindrone, But Not Its A-Ring Reduced Metabolite in Mice Neurotherapeutics. 4: 727-727. DOI: 10.1016/J.NURT.2007.03.011 |
0.512 |
|
2006 |
Rogawski MA. Point-counterpoint: Do interictal spikes trigger seizures or protect against them? Epilepsy Currents / American Epilepsy Society. 6: 197-8. PMID 17260058 DOI: 10.1111/j.1535-7511.2006.00144.x |
0.359 |
|
2006 |
Gasior M, Rogawski MA, Hartman AL. Neuroprotective and disease-modifying effects of the ketogenic diet. Behavioural Pharmacology. 17: 431-9. PMID 16940764 DOI: 10.1097/00008877-200609000-00009 |
0.673 |
|
2006 |
Motamedi GK, Salazar P, Smith EL, Lesser RP, Webber WR, Ortinski PI, Vicini S, Rogawski MA. Termination of epileptiform activity by cooling in rat hippocampal slice epilepsy models. Epilepsy Research. 70: 200-10. PMID 16815680 DOI: 10.1016/J.Eplepsyres.2006.05.001 |
0.387 |
|
2006 |
Biagini G, Baldelli E, Longo D, Pradelli L, Zini I, Rogawski MA, Avoli M. Endogenous neurosteroids modulate epileptogenesis in a model of temporal lobe epilepsy. Experimental Neurology. 201: 519-24. PMID 16780839 DOI: 10.1016/J.Expneurol.2006.04.029 |
0.447 |
|
2006 |
Rogawski MA. Diverse mechanisms of antiepileptic drugs in the development pipeline. Epilepsy Research. 69: 273-94. PMID 16621450 DOI: 10.1016/j.eplepsyres.2006.02.004 |
0.396 |
|
2006 |
Kaminski RM, Marini H, Ortinski PI, Vicini S, Rogawski MA. The pheromone androstenol (5 alpha-androst-16-en-3 alpha-ol) is a neurosteroid positive modulator of GABAA receptors. The Journal of Pharmacology and Experimental Therapeutics. 317: 694-703. PMID 16415088 DOI: 10.1124/Jpet.105.098319 |
0.61 |
|
2006 |
Rogawski MA. Molecular targets versus models for new antiepileptic drug discovery. Epilepsy Research. 68: 22-8. PMID 16377151 DOI: 10.1016/j.eplepsyres.2005.09.012 |
0.354 |
|
2006 |
GASIOR M, TANG R, WHITE N, ROGAWSKI M. Prolonged Attenuation of Amygdla Kindled Seizures by Local Delivery of Large Molecular Weight Therapeutic Agents by Convection-Enhanced Delivery in Rats Neurorx. 3: 414-414. DOI: 10.1016/J.NURX.2006.05.031 |
0.63 |
|
2006 |
KAMINSKI R, MARINI H, ORTINSKI P, YONEKAWA W, VICINI S, ROGAWSKI M. Androstenol (5α-androst-16-en-3α-ol) Is a Novel Neurosteroid Positive Modulator of GABAA Receptors: In Vitro and In Vivo Studies Neurorx. 3: 413-414. DOI: 10.1016/J.Nurx.2006.05.030 |
0.616 |
|
2005 |
Rogawski MA. Update on the neurobiology of alcohol withdrawal seizures. Epilepsy Currents / American Epilepsy Society. 5: 225-30. PMID 16372057 DOI: 10.1111/j.1535-7511.2005.00071.x |
0.414 |
|
2005 |
Rogawski MA. Astrocytes get in the act in epilepsy. Nature Medicine. 11: 919-20. PMID 16145568 DOI: 10.1038/nm0905-919 |
0.376 |
|
2005 |
Gryder DS, Castaneda DC, Rogawski MA. Evidence for low GluR2 AMPA receptor subunit expression at synapses in the rat basolateral amygdala. Journal of Neurochemistry. 94: 1728-38. PMID 16045445 DOI: 10.1111/j.1471-4159.2005.03334.x |
0.333 |
|
2005 |
Kaminski RM, Marini H, Kim WJ, Rogawski MA. Anticonvulsant activity of androsterone and etiocholanolone. Epilepsia. 46: 819-27. PMID 15946323 DOI: 10.1111/j.1528-1167.2005.00705.x |
0.56 |
|
2005 |
Reddy DS, O'Malley BW, Rogawski MA. Anxiolytic activity of progesterone in progesterone receptor knockout mice. Neuropharmacology. 48: 14-24. PMID 15617723 DOI: 10.1016/J.Neuropharm.2004.09.002 |
0.557 |
|
2005 |
Rogawski MA, Macdonald RL, Pedley TA. Larry S. Benardo, MD, PhD 1956–2004 Epilepsy Currents. 5: 159-159. DOI: 10.1111/j.1535-7597.2005.20050704.x |
0.368 |
|
2004 |
Kaminski RM, Banerjee M, Rogawski MA. Topiramate selectively protects against seizures induced by ATPA, a GluR5 kainate receptor agonist. Neuropharmacology. 46: 1097-1104. PMID 32585782 DOI: 10.1016/j.neuropharm.2004.02.010 |
0.639 |
|
2004 |
Ivanov SV, Ward JM, Tessarollo L, McAreavey D, Sachdev V, Fananapazir L, Banks MK, Morris N, Djurickovic D, Devor-Henneman DE, Wei MH, Alvord GW, Gao B, Richardson JA, Minna JD, ... Rogawski MA, et al. Cerebellar ataxia, seizures, premature death, and cardiac abnormalities in mice with targeted disruption of the Cacna2d2 gene. The American Journal of Pathology. 165: 1007-18. PMID 15331424 DOI: 10.1016/S0002-9440(10)63362-7 |
0.355 |
|
2004 |
Rogawski MA. What is the rationale for new treatment strategies in Alzheimer's disease? Cns Spectrums. 9: 6-12. PMID 15241294 DOI: 10.1017/S1092852900024743 |
0.321 |
|
2004 |
Kaminski RM, Livingood MR, Rogawski MA. Allopregnanolone analogs that positively modulate GABA receptors protect against partial seizures induced by 6-Hz electrical stimulation in mice. Epilepsia. 45: 864-7. PMID 15230714 DOI: 10.1111/j.0013-9580.2004.04504.x |
0.648 |
|
2004 |
Rogawski MA, Löscher W. The neurobiology of antiepileptic drugs for the treatment of nonepileptic conditions. Nature Medicine. 10: 685-92. PMID 15229516 DOI: 10.1038/nm1074 |
0.33 |
|
2004 |
Rogawski MA, Löscher W. The neurobiology of antiepileptic drugs. Nature Reviews. Neuroscience. 5: 553-64. PMID 15208697 DOI: 10.1038/nrn1430 |
0.439 |
|
2004 |
Kaminski RM, Banerjee M, Rogawski MA. Topiramate selectively protects against seizures induced by ATPA, a GluR5 kainate receptor agonist. Neuropharmacology. 46: 1097-104. PMID 15111016 DOI: 10.1016/j.neuropharm.2004.02.010 |
0.678 |
|
2004 |
Reddy DS, Castaneda DC, O'Malley BW, Rogawski MA. Anticonvulsant activity of progesterone and neurosteroids in progesterone receptor knockout mice. The Journal of Pharmacology and Experimental Therapeutics. 310: 230-9. PMID 14982969 DOI: 10.1124/Jpet.104.065268 |
0.582 |
|
2003 |
Rogawski MA, Wenk GL. The neuropharmacological basis for the use of memantine in the treatment of Alzheimer's disease. Cns Drug Reviews. 9: 275-308. PMID 14530799 DOI: 10.1111/J.1527-3458.2003.Tb00254.X |
0.392 |
|
2003 |
Salazar P, Tapia R, Rogawski MA. Effects of neurosteroids on epileptiform activity induced by picrotoxin and 4-aminopyridine in the rat hippocampal slice. Epilepsy Research. 55: 71-82. PMID 12948618 DOI: 10.1016/S0920-1211(03)00112-8 |
0.37 |
|
2003 |
Gryder DS, Rogawski MA. Selective antagonism of GluR5 kainate-receptor-mediated synaptic currents by topiramate in rat basolateral amygdala neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7069-74. PMID 12904467 DOI: 10.1523/Jneurosci.23-18-07069.2003 |
0.418 |
|
2003 |
Pearl PL, Gibson KM, Acosta MT, Vezina LG, Theodore WH, Rogawski MA, Novotny EJ, Gropman A, Conry JA, Berry GT, Tuchman M. Clinical spectrum of succinic semialdehyde dehydrogenase deficiency. Neurology. 60: 1413-7. PMID 12743223 DOI: 10.1212/01.Wnl.0000059549.70717.80 |
0.304 |
|
2003 |
Rogawski MA, Gryder D, Castaneda D, Yonekawa W, Banks MK, Lia H. GluR5 kainate receptors, seizures, and the amygdala. Annals of the New York Academy of Sciences. 985: 150-62. PMID 12724156 DOI: 10.1111/J.1749-6632.2003.Tb07079.X |
0.481 |
|
2003 |
Rogawski MA. Progesterone, neurosteroids, and the hormonal basis of catamenial epilepsy. Annals of Neurology. 53: 288-91. PMID 12601696 DOI: 10.1002/ana.10534 |
0.366 |
|
2002 |
Rogawski MA. New Evidence Supporting a Role for T-Type Ca(2+) Channels in Absence Epilepsy and in the Action of Ethosuximide. Epilepsy Currents / American Epilepsy Society. 2: 57. PMID 15309167 DOI: 10.1046/j.1535-7597.2002.00020.x |
0.318 |
|
2002 |
Rogawski MA. Antiepileptogenesis by Deep Brain Stimulation. Epilepsy Currents / American Epilepsy Society. 2: 153-154. PMID 15309125 DOI: 10.1046/j.1535-7597.2002.00057.x |
0.358 |
|
2002 |
Dudek FE, Rogawski MA. The Epileptic Neuron Redux. Epilepsy Currents / American Epilepsy Society. 2: 151-152. PMID 15309124 DOI: 10.1046/j.1535-7597.2002.00056.x |
0.318 |
|
2002 |
Pace JR, Lonser RR, Kirkby RD, Jeffries N, Rogawski MA, Oldfield EH. Epileptiform activity extinguished by amygdala infusion of the neurotoxin ibotenate in a rat model of temporal lobe epilepsy. Journal of Neurosurgery. 97: 450-4. PMID 12186475 DOI: 10.3171/jns.2002.97.2.0450 |
0.449 |
|
2002 |
Schmidt D, Rogawski MA. New strategies for the identification of drugs to prevent the development or progression of epilepsy. Epilepsy Research. 50: 71-8. PMID 12151119 DOI: 10.1016/S0920-1211(02)00070-0 |
0.357 |
|
2002 |
Rogawski MA, Reddy DS. Neurosteroids and infantile spasms: the deoxycorticosterone hypothesis. International Review of Neurobiology. 49: 199-219. PMID 12040893 DOI: 10.1016/S0074-7742(02)49014-9 |
0.611 |
|
2002 |
Reddy DS, Rogawski MA. Stress-induced deoxycorticosterone-derived neurosteroids modulate GABA(A) receptor function and seizure susceptibility. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 3795-805. PMID 11978855 DOI: 10.1523/Jneurosci.22-09-03795.2002 |
0.647 |
|
2001 |
Basile AS, Koustova E, Ioan P, Rizzoli S, Rogawski MA, Usherwood PN. IgG isolated from LP-BM5 infected mouse brain activates ionotropic glutamate receptors. Neurobiology of Disease. 8: 1069-81. PMID 11741402 DOI: 10.1006/Nbdi.2001.0442 |
0.365 |
|
2001 |
Jacobs MP, Fischbach GD, Davis MR, Dichter MA, Dingledine R, Lowenstein DH, Morrell MJ, Noebels JL, Rogawski MA, Spencer SS, Theodore WH. Future directions for epilepsy research. Neurology. 57: 1536-42. PMID 11706087 DOI: 10.1212/Wnl.57.9.1536 |
0.406 |
|
2001 |
Reddy DS, Rogawski MA. Enhanced anticonvulsant activity of neuroactive steroids in a rat model of catamenial epilepsy. Epilepsia. 42: 337-44. PMID 11442150 DOI: 10.1046/j.1528-1157.2001.10200.x |
0.632 |
|
2001 |
Reddy DS, Kim HY, Rogawski MA. Neurosteroid withdrawal model of perimenstrual catamenial epilepsy. Epilepsia. 42: 328-36. PMID 11442149 DOI: 10.1046/j.1528-1157.2001.10100.x |
0.643 |
|
2001 |
Li H, Chen A, Xing G, Wei ML, Rogawski MA. Kainate receptor-mediated heterosynaptic facilitation in the amygdala. Nature Neuroscience. 4: 612-20. PMID 11369942 DOI: 10.1038/88432 |
0.321 |
|
2001 |
Koustova E, Sei Y, Fossom L, Wei ML, Usherwood PN, Keele NB, Rogawski MA, Basile AS. LP-BM5 virus-infected mice produce activating autoantibodies to the AMPA receptor. The Journal of Clinical Investigation. 107: 737-44. PMID 11254673 DOI: 10.1172/Jci11500 |
0.368 |
|
2001 |
Rogawski MA, Kurzman PS, Yamaguchi SI, Li H. Role of AMPA and GluR5 kainate receptors in the development and expression of amygdala kindling in the mouse. Neuropharmacology. 40: 28-35. PMID 11077068 DOI: 10.1016/S0028-3908(00)00112-X |
0.499 |
|
2000 |
Reddy DS, Rogawski MA. Chronic treatment with the neuroactive steroid ganaxolone in the rat induces anticonvulsant tolerance to diazepam but not to itself. The Journal of Pharmacology and Experimental Therapeutics. 295: 1241-8. PMID 11082461 |
0.541 |
|
2000 |
Rogawski MA. Low affinity channel blocking (uncompetitive) NMDA receptor antagonists as therapeutic agents--toward an understanding of their favorable tolerability. Amino Acids. 19: 133-49. PMID 11026482 DOI: 10.1007/s007260070042 |
0.42 |
|
2000 |
Reddy DS, Rogawski MA. Enhanced anticonvulsant activity of ganaxolone after neurosteroid withdrawal in a rat model of catamenial epilepsy. The Journal of Pharmacology and Experimental Therapeutics. 294: 909-15. PMID 10945840 |
0.598 |
|
2000 |
Rogawski MA. KCNQ2/KCNQ3 K+ channels and the molecular pathogenesis of epilepsy: implications for therapy. Trends in Neurosciences. 23: 393-8. PMID 10941184 DOI: 10.1016/S0166-2236(00)01629-5 |
0.364 |
|
2000 |
Rogawski MA, Wasterlain CG, Mazarati AM. Re: Mazarati et al. "...clinically available [antiepileptic drug] with a moderate affinity for the glycine site of the N-methyl-D-aspartate (NMDA) receptor". Epilepsia. 41: 918-9. PMID 10897169 DOI: 10.1111/J.1528-1157.2000.Tb00265.X |
0.326 |
|
2000 |
Mothet JP, Parent AT, Wolosker H, Brady RO, Linden DJ, Ferris CD, Rogawski MA, Snyder SH. D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor. Proceedings of the National Academy of Sciences of the United States of America. 97: 4926-31. PMID 10781100 DOI: 10.1073/Pnas.97.9.4926 |
0.53 |
|
2000 |
Harty TP, Rogawski MA. Felbamate block of recombinant N-methyl-D-aspartate receptors: selectivity for the NR2B subunit. Epilepsy Research. 39: 47-55. PMID 10690753 DOI: 10.1016/S0920-1211(99)00108-4 |
0.39 |
|
2000 |
Rogawski M. Of blind men and brain steroids Trends in Pharmacological Sciences. 21: 33. DOI: 10.1016/S0165-6147(99)01409-1 |
0.37 |
|
1999 |
Rogawski MA, Donevan SD. AMPA receptors in epilepsy and as targets for antiepileptic drugs. Advances in Neurology. 79: 947-63. PMID 10514878 |
0.723 |
|
1999 |
Kokate TG, Juhng KN, Kirkby RD, Llamas J, Yamaguchi S, Rogawski MA. Convulsant actions of the neurosteroid pregnenolone sulfate in mice. Brain Research. 831: 119-24. PMID 10411990 DOI: 10.1016/S0006-8993(99)01287-1 |
0.833 |
|
1999 |
Juhng KN, Kokate TG, Yamaguchi S, Kim BY, Rogowski RS, Blaustein MP, Rogawski MA. Induction of seizures by the potent K+ channel-blocking scorpion venom peptide toxins tityustoxin-K(alpha) and pandinustoxin-K(alpha). Epilepsy Research. 34: 177-86. PMID 10210033 DOI: 10.1016/S0920-1211(98)00111-9 |
0.796 |
|
1999 |
Kokate TG, Banks MK, Magee T, Yamaguchi S, Rogawski MA. Finasteride, a 5alpha-reductase inhibitor, blocks the anticonvulsant activity of progesterone in mice. The Journal of Pharmacology and Experimental Therapeutics. 288: 679-84. PMID 9918575 |
0.799 |
|
1998 |
Li H, Rogawski MA. GluR5 kainate receptor mediated synaptic transmission in rat basolateral amygdala in vitro. Neuropharmacology. 37: 1279-86. PMID 9849665 DOI: 10.1016/S0028-3908(98)00109-9 |
0.369 |
|
1998 |
Kokate TG, Yamaguchi S, Pannell LK, Rajamani U, Carroll DM, Grossman AB, Rogawski MA. Lack of anticonvulsant tolerance to the neuroactive steroid pregnanolone in mice. The Journal of Pharmacology and Experimental Therapeutics. 287: 553-8. PMID 9808680 |
0.794 |
|
1998 |
Donevan SD, Rogawski MA. Allosteric regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionate receptors by thiocyanate and cyclothiazide at a common modulatory site distinct from that of 2,3-benzodiazepines. Neuroscience. 87: 615-29. PMID 9758228 DOI: 10.1016/S0306-4522(98)00109-2 |
0.725 |
|
1998 |
Grauert M, Rho JM, Subramaniam S, Rogawski MA. N-methyl-D-aspartate receptor channel block by the enantiomeric 6,7-benzomorphans BIII 277 CL and BIII 281 CL. The Journal of Pharmacology and Experimental Therapeutics. 285: 767-76. PMID 9580625 |
0.588 |
|
1998 |
Li H, Weiss SR, Chuang DM, Post RM, Rogawski MA. Bidirectional synaptic plasticity in the rat basolateral amygdala: characterization of an activity-dependent switch sensitive to the presynaptic metabotropic glutamate receptor antagonist 2S-alpha-ethylglutamic acid. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 1662-70. PMID 9464991 DOI: 10.1523/Jneurosci.18-05-01662.1998 |
0.338 |
|
1997 |
Rho JM, Donevan SD, Rogawski MA. Barbiturate-like actions of the propanediol dicarbamates felbamate and meprobamate. The Journal of Pharmacology and Experimental Therapeutics. 280: 1383-91. PMID 9067327 |
0.752 |
|
1996 |
Kokate TG, Cohen AL, Karp E, Rogawski MA. Neuroactive steroids protect against pilocarpine- and kainic acid-induced limbic seizures and status epilepticus in mice. Neuropharmacology. 35: 1049-56. PMID 9121607 DOI: 10.1016/S0028-3908(96)00021-4 |
0.817 |
|
1996 |
Grant KA, Colombo G, Grant J, Rogawski MA. Dizocilpine-like discriminative stimulus effects of low-affinity uncompetitive NMDA antagonists. Neuropharmacology. 35: 1709-19. PMID 9076750 DOI: 10.1016/S0028-3908(96)00147-5 |
0.366 |
|
1996 |
Rho JM, Donevan SD, Rogawski MA. Direct activation of GABAA receptors by barbiturates in cultured rat hippocampal neurons. The Journal of Physiology. 497: 509-22. PMID 8961191 DOI: 10.1113/Jphysiol.1996.Sp021784 |
0.757 |
|
1996 |
Poling JS, Rogawski MA, Salem N, Vicini S. Anandamide, an endogenous cannabinoid, inhibits Shaker-related voltage-gated K+ channels. Neuropharmacology. 35: 983-91. PMID 8938728 DOI: 10.1016/0028-3908(96)00130-X |
0.352 |
|
1996 |
Poling JS, Vicini S, Rogawski MA, Salem N. Docosahexaenoic acid block of neuronal voltage-gated K+ channels: subunit selective antagonism by zinc. Neuropharmacology. 35: 969-82. PMID 8938727 DOI: 10.1016/0028-3908(96)00127-X |
0.318 |
|
1996 |
Rogowski RS, Collins JH, O'Neill TJ, Gustafson TA, Werkman TR, Rogawski MA, Tenenholz TC, Weber DJ, Blaustein MP. Three new toxins from the scorpion Pandinus imperator selectively block certain voltage-gated K+ channels. Molecular Pharmacology. 50: 1167-77. PMID 8913348 |
0.667 |
|
1996 |
Donevan SD, Rogawski MA. Multiple actions of arylalkylamine arthropod toxins on the N-methyl-D-aspartate receptor. Neuroscience. 70: 361-75. PMID 8848146 DOI: 10.1016/0306-4522(95)00342-8 |
0.704 |
|
1996 |
Chen K, Kokate TG, Donevan SD, Carroll FI, Rogawski MA. Ibogaine block of the NMDA receptor: in vitro and in vivo studies. Neuropharmacology. 35: 423-31. PMID 8793904 DOI: 10.1016/0028-3908(96)84107-4 |
0.805 |
|
1996 |
Subramaniam S, Donevan SD, Rogawski MA. Block of the N-methyl-D-aspartate receptor by remacemide and its des-glycine metabolite. The Journal of Pharmacology and Experimental Therapeutics. 276: 161-8. PMID 8558426 |
0.698 |
|
1996 |
Rho JM, Donevan SD, Rogawski MA. Direct activation of GABA(A) receptors by barbiturates in cultured rat hippocampal neurons Journal of Physiology. 497: 509-522. |
0.74 |
|
1995 |
Lapin IP, Rogawski MA. Effects of D1 and D2 dopamine receptor antagonists and catecholamine depleting agents on the locomotor stimulation induced by dizocilpine in mice. Behavioural Brain Research. 70: 145-51. PMID 8561905 DOI: 10.1016/0166-4328(95)80004-2 |
0.352 |
|
1995 |
Subramaniam S, Rho JM, Penix L, Donevan SD, Fielding RP, Rogawski MA. Felbamate block of the N-methyl-D-aspartate receptor. The Journal of Pharmacology and Experimental Therapeutics. 273: 878-86. PMID 7752093 |
0.758 |
|
1995 |
Donevan SD, Rogawski MA. Intracellular polyamines mediate inward rectification of Ca(2+)-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors. Proceedings of the National Academy of Sciences of the United States of America. 92: 9298-302. PMID 7568121 DOI: 10.1073/Pnas.92.20.9298 |
0.712 |
|
1995 |
Rogawski MA, Le DQ, Uyakul D, Pannell LK, Subramaniam S, Yamaguchi S, Kokate TG. Anticonvulsant efficacy of ADCI (5-aminocarbonyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine) after acute and chronic dosing in mice. Epilepsia. 36: 566-71. PMID 7555968 DOI: 10.1111/j.1528-1157.1995.tb02568.x |
0.794 |
|
1994 |
Subramaniam S, Donevan SD, Rogawski MA. Hydrophobic interactions of n-alkyl diamines with the N-methyl-D-aspartate receptor: voltage-dependent and -independent blocking sites. Molecular Pharmacology. 45: 117-24. PMID 8302270 |
0.661 |
|
1994 |
Rho JM, Donevan SD, Rogawski MA. Mechanism of action of the anticonvulsant felbamate: opposing effects on N-methyl-D-aspartate and gamma-aminobutyric acidA receptors. Annals of Neurology. 35: 229-34. PMID 8109904 DOI: 10.1002/ana.410350216 |
0.795 |
|
1994 |
Sofia RD, Rho JM, Donevan SD, Subramaniam S, Rogawski MA. Mechanism of action of the anticonvulsant felbamate: Opposing effects on N-methyl-D-aspartate and γ-aminobutyric acid(A) receptors [1] Annals of Neurology. 36: 677-678. PMID 7944305 |
0.741 |
|
1994 |
Svensson BE, Werkman TR, Rogawski MA. Alaproclate effects on voltage-dependent K+ channels and NMDA receptors: studies in cultured rat hippocampal neurons and fibroblast cells transformed with Kv1.2 K+ channel cDNA. Neuropharmacology. 33: 795-804. PMID 7936117 DOI: 10.1016/0028-3908(94)90119-8 |
0.739 |
|
1994 |
Kokate TG, Svensson BE, Rogawski MA. Anticonvulsant activity of neurosteroids: correlation with gamma-aminobutyric acid-evoked chloride current potentiation. The Journal of Pharmacology and Experimental Therapeutics. 270: 1223-9. PMID 7932175 |
0.797 |
|
1994 |
Mattia D, Nagao T, Rogawski MA, Avoli M. Potassium channel activators counteract anoxic hyperexcitability but not 4-aminopyridine-induced epileptiform activity in the rat hippocampal slice. Neuropharmacology. 33: 1515-22. PMID 7760973 DOI: 10.1016/0028-3908(94)90124-4 |
0.369 |
|
1994 |
Donevan SD, Yamaguchi S, Rogawski MA. Non-N-methyl-D-aspartate receptor antagonism by 3-N-substituted 2,3-benzodiazepines: relationship to anticonvulsant activity. The Journal of Pharmacology and Experimental Therapeutics. 271: 25-9. PMID 7525924 |
0.702 |
|
1993 |
Werkman TR, Gustafson TA, Rogowski RS, Blaustein MP, Rogawski MA. Tityustoxin-K alpha, a structurally novel and highly potent K+ channel peptide toxin, interacts with the alpha-dendrotoxin binding site on the cloned Kv1.2 K+ channel. Molecular Pharmacology. 44: 430-6. PMID 8355670 |
0.666 |
|
1993 |
ffrench-Mullen JM, Barker JL, Rogawski MA. Calcium current block by (-)-pentobarbital, phenobarbital, and CHEB but not (+)-pentobarbital in acutely isolated hippocampal CA1 neurons: comparison with effects on GABA-activated Cl- current. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 3211-21. PMID 8101867 DOI: 10.1523/Jneurosci.13-08-03211.1993 |
0.337 |
|
1993 |
Yamaguchi S, Donevan SD, Rogawski MA. Anticonvulsant activity of AMPA/kainate antagonists: comparison of GYKI 52466 and NBOX in maximal electroshock and chemoconvulsant seizure models. Epilepsy Research. 15: 179-84. PMID 7693450 DOI: 10.1016/0920-1211(93)90054-B |
0.752 |
|
1993 |
Donevan SD, Rogawski MA. GYKI 52466, a 2,3-benzodiazepine, is a highly selective, noncompetitive antagonist of AMPA/kainate receptor responses. Neuron. 10: 51-9. PMID 7678966 DOI: 10.1016/0896-6273(93)90241-I |
0.726 |
|
1993 |
Rogawski MA. Therapeutic potential of excitatory amino acid antagonists: channel blockers and 2,3-benzodiazepines. Trends in Pharmacological Sciences. 14: 325-31. PMID 7504360 DOI: 10.1016/0165-6147(93)90005-5 |
0.405 |
|
1992 |
Lapin IP, Rogawski MA. Muscarinic antagonists attenuate dizocilpine-induced hypermotility in mice. Life Sciences. 50: PL59-64. PMID 1740967 DOI: 10.1016/0024-3205(92)90254-M |
0.39 |
|
1992 |
Yamaguchi S, Rogawski MA. Effects of anticonvulsant drugs on 4-aminopyridine-induced seizures in mice. Epilepsy Research. 11: 9-16. PMID 1563341 DOI: 10.1016/0920-1211(92)90016-M |
0.489 |
|
1992 |
Blake PA, Yamaguchi S, Thurkauf A, Rogawski MA. Anticonvulsant 1-phenylcycloalkylamines: two analogues with low motor toxicity when orally administered. Epilepsia. 33: 188-94. PMID 1531130 DOI: 10.1111/J.1528-1157.1992.Tb02305.X |
0.422 |
|
1992 |
Coleman MH, Yamaguchi S, Rogawski MA. Protection against dendrotoxin-induced clonic seizures in mice by anticonvulsant drugs. Brain Research. 575: 138-42. PMID 1504773 DOI: 10.1016/0006-8993(92)90433-A |
0.484 |
|
1992 |
Irwin RP, Maragakis NJ, Rogawski MA, Purdy RH, Farb DH, Paul SM. Pregnenolone sulfate augments NMDA receptor mediated increases in intracellular Ca2+ in cultured rat hippocampal neurons. Neuroscience Letters. 141: 30-4. PMID 1387199 DOI: 10.1016/0304-3940(92)90327-4 |
0.351 |
|
1992 |
Rogawski MA. The NMDA receptor, NMDA antagonists and epilepsy therapy. A status report. Drugs. 44: 279-92. PMID 1382930 DOI: 10.2165/00003495-199244030-00001 |
0.388 |
|
1992 |
Porter RJ, Rogawski MA. New antiepileptic drugs: from serendipity to rational discovery. Epilepsia. 33: S1-6. PMID 1379532 DOI: 10.1111/J.1528-1157.1992.Tb05895.X |
0.472 |
|
1992 |
Donevan SD, Jones SM, Rogawski MA. Arcaine blocks N-methyl-D-aspartate receptor responses by an open channel mechanism: whole-cell and single-channel recording studies in cultured hippocampal neurons. Molecular Pharmacology. 41: 727-35. PMID 1373801 |
0.696 |
|
1992 |
Ffrench-Mullen JM, Rogawski MA. Phencyclidine block of calcium current in isolated guinea-pig hippocampal neurones. The Journal of Physiology. 456: 85-105. PMID 1338108 DOI: 10.1113/Jphysiol.1992.Sp019328 |
0.324 |
|
1992 |
Pace JR, Martin BM, Paul SM, Rogawski MA. High concentrations of neutral amino acids activate NMDA receptor currents in rat hippocampal neurons. Neuroscience Letters. 141: 97-100. PMID 1324446 DOI: 10.1016/0304-3940(92)90343-6 |
0.357 |
|
1992 |
Subramaniam S, Donevan SD, Rogawski MA. 1,10-Diaminodecane and 1,12-diaminododecane block NMDA receptor currents by an open channel mechanism. Neuroscience Letters. 147: 213-6. PMID 1283458 DOI: 10.1016/0304-3940(92)90598-2 |
0.702 |
|
1992 |
Werkman TR, Kawamura T, Yokoyama S, Higashida H, Rogawski MA. Charybdotoxin, dendrotoxin and mast cell degranulating peptide block the voltage-activated K+ current of fibroblast cells stably transfected with NGK1 (Kv1.2) K+ channel complementary DNA. Neuroscience. 50: 935-46. PMID 1280351 DOI: 10.1016/0306-4522(92)90216-O |
0.696 |
|
1991 |
Rogawski MA, Yamaguchi S, Jones SM, Rice KC, Thurkauf A, Monn JA. Anticonvulsant activity of the low-affinity uncompetitive N-methyl-D- aspartate antagonist (+-)-5-aminocarbonyl-10,11-dihydro-5H- dibenzo[a,d]cyclohepten-5,10-imine (ADCI): comparison with the structural analogs dizocilpine (MK-801) and carbamazepine. The Journal of Pharmacology and Experimental Therapeutics. 259: 30-7. PMID 1920122 |
0.381 |
|
1991 |
Hershkowitz N, Rogawski MA. Tetrahydroaminoacridine block of N-methyl-D-aspartate-activated cation channels in cultured hippocampal neurons. Molecular Pharmacology. 39: 592-8. PMID 1709720 |
0.564 |
|
1991 |
Wang XJ, Rinzel J, Rogawski MA. A model of the T-type calcium current and the low-threshold spike in thalamic neurons. Journal of Neurophysiology. 66: 839-50. PMID 1661326 DOI: 10.1152/Jn.1991.66.3.839 |
0.3 |
|
1990 |
Thurkauf A, de Costa B, Yamaguchi S, Mattson MV, Jacobson AE, Rice KC, Rogawski MA. Synthesis and anticonvulsant activity of 1-phenylcyclohexylamine analogues. Journal of Medicinal Chemistry. 33: 1452-8. PMID 2329567 DOI: 10.1021/Jm00167A027 |
0.384 |
|
1990 |
Rogawski MA, Hershkowitz N, Politi DM, Suzuki S, Thurkauf A, Yamaguchi S. Novel research strategies for antiepileptic therapy. Progress in Clinical and Biological Research. 361: 91-111. PMID 2290852 |
0.434 |
|
1989 |
Rogawski MA, Thurkauf A, Yamaguchi S, Rice KC, Jacobson AE, Mattson MV. Anticonvulsant activities of 1-phenylcyclohexylamine and its conformationally restricted analog 1,1-pentamethylenetetrahydroisoquinoline. The Journal of Pharmacology and Experimental Therapeutics. 249: 708-12. PMID 2659775 |
0.332 |
|
1989 |
Politi DM, Suzuki S, Rogawski MA. BRL 34915 (cromakalim) enhances voltage-dependent K+ current in cultured rat hippocampal neurons. European Journal of Pharmacology. 168: 7-14. PMID 2583232 DOI: 10.1016/0014-2999(89)90626-2 |
0.349 |
|
1989 |
Hershkowitz N, Rogawski MA. Cycloleucine blocks NMDA responses in cultured hippocampal neurones under voltage clamp: antagonism at the strychnine-insensitive glycine receptor. British Journal of Pharmacology. 98: 1005-13. PMID 2556198 DOI: 10.1111/J.1476-5381.1989.Tb14632.X |
0.614 |
|
1989 |
ffrench-Mullen JM, Rogawski MA. Interaction of phencyclidine with voltage-dependent potassium channels in cultured rat hippocampal neurons: comparison with block of the NMDA receptor-ionophore complex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 9: 4051-61. PMID 2555461 DOI: 10.1523/Jneurosci.09-11-04051.1989 |
0.387 |
|
1989 |
Suzuki S, Rogawski MA. T-type calcium channels mediate the transition between tonic and phasic firing in thalamic neurons. Proceedings of the National Academy of Sciences of the United States of America. 86: 7228-32. PMID 2550936 DOI: 10.1073/Pnas.86.18.7228 |
0.3 |
|
1988 |
ffrench-Mullen JM, Rogawski MA, Barker JL. Phencyclidine at low concentrations selectively blocks the sustained but not the transient voltage-dependent potassium current in cultured hippocampal neurons. Neuroscience Letters. 88: 325-30. PMID 3386879 DOI: 10.1016/0304-3940(88)90232-7 |
0.33 |
|
1988 |
Rogawski MA. Transient outward current (IA) in clonal anterior pituitary cells: blockade by aminopyridine analogs. Naunyn-Schmiedeberg's Archives of Pharmacology. 338: 125-32. PMID 3185742 DOI: 10.1007/BF00174859 |
0.317 |
|
1988 |
Rogawski MA, Pieniek M, Suzuki S, ffrench-Mullen JM. Phencyclidine selectively blocks the sustained voltage-dependent potassium conductance in PC12 cells. Brain Research. 456: 38-48. PMID 2457411 DOI: 10.1016/0006-8993(88)90344-7 |
0.38 |
|
1987 |
Mollard P, Vacher P, Guerin J, Rogawski MA, Dufy B. Electrical properties of cultured human adrenocorticotropin-secreting adenoma cells: effects of high K+, corticotropin-releasing factor, and angiotensin II. Endocrinology. 121: 395-405. PMID 3036472 DOI: 10.1210/endo-121-1-395 |
0.307 |
|
1987 |
Rogawski MA. Tetrahydroaminoacridine blocks voltage-dependent ion channels in hippocampal neurons. European Journal of Pharmacology. 142: 169-72. PMID 2446884 DOI: 10.1016/0014-2999(87)90670-4 |
0.347 |
|
1986 |
Rogawski MA. Single voltage-dependent potassium channels in cultured rat hippocampal neurons. Journal of Neurophysiology. 56: 481-93. PMID 2428951 DOI: 10.1152/Jn.1986.56.2.481 |
0.318 |
|
1984 |
Segal M, Rogawski M, Barker J. A transient potassium conductance regulates the excitability of cultured hippocampal and spinal neurons The Journal of Neuroscience. 4: 604-609. DOI: 10.1523/JNEUROSCI.04-02-00604.1984 |
0.325 |
|
1983 |
Aghajanian GK, Rogawski MA. The physiological role of α-adrenoceptors in the CNS: new concepts from single-cell studies Trends in Pharmacological Sciences. 4: 315-317. DOI: 10.1016/0165-6147(83)90417-0 |
0.48 |
|
1982 |
Rogawski MA, Aghajanian GK. Activation of lateral geniculate neurons by locus coeruleus or dorsal noradrenergic bundle stimulation: selective blockade by the alpha 1-adrenoceptor antagonist prazosin. Brain Research. 250: 31-9. PMID 7139319 DOI: 10.1016/0006-8993(82)90950-7 |
0.545 |
|
1982 |
Rogawski MA. Cholecystokinin octapeptide: effects on the excitability of cultured spinal neurons. Peptides. 3: 545-51. PMID 6126867 DOI: 10.1016/0196-9781(82)90124-3 |
0.318 |
|
1981 |
Rogawski MA, Aghajanian GK. Serotonin autoreceptors on dorsal raphe neurons: structure-activity relationships of tryptamine analogs. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 1: 1148-54. PMID 6793698 DOI: 10.1523/Jneurosci.01-10-01148.1981 |
0.481 |
|
1980 |
Rogawski MA, Aghajanian GK. Norepinephrine and serotonin: opposite effects on the activity of lateral geniculate neurons evoked by optic pathway stimulation. Experimental Neurology. 69: 678-94. PMID 7409069 DOI: 10.1016/0014-4886(80)90060-6 |
0.509 |
|
1980 |
Rogawski MA, Aghajanian GK. Modulation of lateral geniculate neurone excitability by noradrenaline microiontophoresis or locus coeruleus stimulation. Nature. 287: 731-4. PMID 6253811 DOI: 10.1038/287731a0 |
0.53 |
|
1980 |
Rogawski MA, Aghajanian GK. Activation of lateral geniculate neurons by norepinephrine: mediation by an alpha-adrenergic receptor. Brain Research. 182: 345-59. PMID 6101983 DOI: 10.1016/0006-8993(80)91193-2 |
0.564 |
|
1979 |
Rogawski MA, Aghajanian GK. Response of central monoaminergic neurons to lisuride: comparison with LSD. Life Sciences. 24: 1289-97. PMID 470543 DOI: 10.1016/0024-3205(79)90148-6 |
0.518 |
|
1979 |
Rogawski MA, Roth RH, Aghajanian GK. Melatonin: deacetylation to 5-methoxytryptamine by liver but not brain aryl acylamidase. Journal of Neurochemistry. 32: 1219-26. PMID 285213 DOI: 10.1111/j.1471-4159.1979.tb11049.x |
0.475 |
|
1974 |
Hoeldtke R, Rogawski M, Wurtman RJ. Effect of selective destruction of central and peripheral catecholamine containing neurones with 6 hydroxydopamine on catecholamine excretion in the rat Brit.J.Pharmacol.. 50: 265-270. PMID 4425765 DOI: 10.1111/j.1476-5381.1974.tb08571.x |
0.443 |
|
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