| Year |
Citation |
Score |
| 2023 |
Keng VW, Chiu AP, To JC, Li XX, Linden MA, Amin K, Moriarity BS, Yusa K. Transposon delivery for CRISPR-based loss-of-function screen in mice identifies NF2 as a cooperating gene involved with the canonical WNT signaling molecular class of hepatocellular carcinoma. Heliyon. 9: e18774. PMID 37576222 DOI: 10.1016/j.heliyon.2023.e18774 |
0.334 |
|
| 2023 |
Sugita K, Onishi I, Nakayama R, Ishibashi S, Ikeda M, Inoue M, Narita R, Oshima S, Shimizu K, Saito S, Sato S, Moriarity BS, Yamamoto K, Largaespada DA, Kitagawa M, et al. Indirect CRISPR screening with photoconversion revealed key factors of drug resistance with cell-cell interactions. Communications Biology. 6: 582. PMID 37264057 DOI: 10.1038/s42003-023-04941-9 |
0.53 |
|
| 2022 |
Becklin KL, Draper GM, Madden RA, Kluesner MG, Koga T, Huang M, Weiss WA, Spector LG, Largaespada DA, Moriarity BS, Webber BR. Developing Bottom-Up Induced Pluripotent Stem Cell Derived Solid Tumor Models Using Precision Genome Editing Technologies. The Crispr Journal. 5: 517-535. PMID 35972367 DOI: 10.1089/crispr.2022.0032 |
0.541 |
|
| 2022 |
Naeimi Kararoudi M, Likhite S, Elmas E, Yamamoto K, Schwartz M, Sorathia K, de Souza Fernandes Pereira M, Sezgin Y, Devine RD, Lyberger JM, Behbehani GK, Chakravarti N, Moriarity BS, Meyer K, Lee DA. Optimization and validation of CAR transduction into human primary NK cells using CRISPR and AAV. Cell Reports Methods. 2: 100236. PMID 35784645 DOI: 10.1016/j.crmeth.2022.100236 |
0.335 |
|
| 2021 |
Yang J, Liao Q, Price M, Moriarity B, Wolf N, Felices M, Miller JS, Geller MA, Bendzick L, Hopps R, Starr TK, O'Connor CH, Tarullo S, Nelson AC, Turley E, et al. Chondroitin sulfate proteoglycan 4, a targetable oncoantigen that promotes ovarian cancer growth, invasion, cisplatin resistance and spheroid formation. Translational Oncology. 16: 101318. PMID 34942534 DOI: 10.1016/j.tranon.2021.101318 |
0.384 |
|
| 2021 |
Robbins GM, Wang M, Pomeroy EJ, Moriarity BS. Nonviral genome engineering of natural killer cells. Stem Cell Research & Therapy. 12: 350. PMID 34134774 DOI: 10.1186/s13287-021-02406-6 |
0.312 |
|
| 2021 |
Vélez-Reyes GL, Koes N, Ryu JH, Kaufmann G, Berner M, Weg MT, Wolf NK, Rathe SK, Ratner N, Moriarity BS, Largaespada DA. Transposon Mutagenesis-Guided CRISPR/Cas9 Screening Strongly Implicates Dysregulation of Hippo/YAP Signaling in Malignant Peripheral Nerve Sheath Tumor Development. Cancers. 13. PMID 33808166 DOI: 10.3390/cancers13071584 |
0.815 |
|
| 2021 |
To JC, Chiu AP, Tschida BR, Lo LH, Chiu CH, Li XX, Kuka TP, Linden MA, Amin K, Chan WC, Bell JB, Moriarity BS, Largaespada DA, Keng VW. ZBTB20 regulates WNT/CTNNB1 signalling pathway by suppressing PPARG during hepatocellular carcinoma tumourigenesis. Jhep Reports : Innovation in Hepatology. 3: 100223. PMID 33604532 DOI: 10.1016/j.jhepr.2020.100223 |
0.438 |
|
| 2020 |
Naeimi Kararoudi M, Tullius BP, Chakraravarti N, Pomeroy EJ, Moriarity BS, Beland K, Colamartino ABL, Haddad E, Chu Y, Cairo MS, Lee DA. Genetic and epigenetic modification of human primary NK cells for enhanced antitumor activity. Seminars in Hematology. 57: 201-212. PMID 33256913 DOI: 10.1053/j.seminhematol.2020.11.006 |
0.315 |
|
| 2020 |
Laoharawee K, Johnson MJ, Lahr WS, Peterson JJ, Webber BR, Moriarity BS. Genome Engineering of Primary Human B Cells Using CRISPR/Cas9. Journal of Visualized Experiments : Jove. PMID 33226023 DOI: 10.3791/61855 |
0.307 |
|
| 2020 |
Smeester BA, Draper GM, Slipek NJ, Larsson AT, Stratton N, Pomeroy EJ, Becklin KL, Yamamoto K, Williams KB, Laoharawee K, Peterson JJ, Abrahante JE, Rathe SK, Mills LJ, Crosby MR, ... ... Moriarity BS, et al. Implication of ZNF217 in accelerating tumor development and therapeutically targeting ZNF217-induced PI3K-AKT signaling for the treatment of metastatic osteosarcoma. Molecular Cancer Therapeutics. PMID 32999043 DOI: 10.1158/1535-7163.MCT-20-0369 |
0.818 |
|
| 2020 |
Lerner T, Kluesner M, Tasakis RN, Moriarity BS, Papavasiliou FN, Pecori R. C-to-U RNA Editing: From Computational Detection to Experimental Validation. Methods in Molecular Biology (Clifton, N.J.). 2181: 51-67. PMID 32729074 DOI: 10.1007/978-1-0716-0787-9_4 |
0.302 |
|
| 2020 |
Wierson WA, Welker JM, Almeida MP, Mann CM, Webster DA, Torrie ME, Weiss TJ, Kambakam S, Vollbrecht MK, Lan M, McKeighan KC, Levey J, Ming Z, Wehmeier A, Mikelson CS, ... ... Moriarity BS, et al. Efficient targeted integration directed by short homology in zebrafish and mammalian cells. Elife. 9. PMID 32412410 DOI: 10.7554/Elife.53968 |
0.39 |
|
| 2020 |
Hsu RYC, Lin YC, Redon C, Sun Q, Singh DK, Wang Y, Aggarwal V, Mitra J, Matur A, Moriarity B, Ha T, Aladjem MI, Prasanth KV, Prasanth SG. ORCA/LRWD1 Regulates Homologous Recombination at ALT-Telomeres by Modulating Heterochromatin Organization. Iscience. 23: 101038. PMID 32344376 DOI: 10.1016/J.Isci.2020.101038 |
0.334 |
|
| 2020 |
Smeester BA, Slipek NJ, Pomeroy EJ, Laoharawee K, Osum SH, Larsson AT, Williams KB, Stratton N, Yamamoto K, Peterson JJ, Rathe SK, Mills LJ, Hudson WA, Crosby MR, Wang M, ... ... Moriarity BS, et al. PLX3397 treatment inhibits constitutive CSF1R-induced oncogenic ERK signaling, reduces tumor growth, and metastatic burden in osteosarcoma. Bone. 115353. PMID 32251854 DOI: 10.1016/J.Bone.2020.115353 |
0.825 |
|
| 2020 |
Laoharawee K, Johnson MJ, Moriarity BS. CRISPR/Cas9-Mediated Genome Engineering of Primary Human B Cells. Methods in Molecular Biology (Clifton, N.J.). 2115: 435-444. PMID 32006415 DOI: 10.1007/978-1-0716-0290-4_24 |
0.386 |
|
| 2020 |
Wierson WA, Welker JM, Almeida MP, Mann CM, Webster DA, Torrie ME, Weiss TJ, Kambakam S, Vollbrecht MK, Lan M, McKeighan KC, Levey J, Ming Z, Wehmeier A, Mikelson CS, ... ... Moriarity BS, et al. Author response: Efficient targeted integration directed by short homology in zebrafish and mammalian cells Elife. DOI: 10.7554/Elife.53968.Sa2 |
0.314 |
|
| 2019 |
Webber BR, Lonetree CL, Kluesner MG, Johnson MJ, Pomeroy EJ, Diers MD, Lahr WS, Draper GM, Slipek NJ, Smeester BS, Lovendahl KN, McElroy AN, Gordon WR, Osborn MJ, Moriarity BS. Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors. Nature Communications. 10: 5222. PMID 31745080 DOI: 10.1038/S41467-019-13007-6 |
0.396 |
|
| 2019 |
Pomeroy EJ, Hunzeker JT, Kluesner MG, Lahr WS, Smeester BA, Crosby MR, Lonetree CL, Yamamoto K, Bendzick L, Miller JS, Geller MA, Walcheck B, Felices M, Webber BR, Starr TK, ... Moriarity BS, et al. A Genetically Engineered Primary Human Natural Killer Cell Platform for Cancer Immunotherapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 31704085 DOI: 10.1016/J.Ymthe.2019.10.009 |
0.423 |
|
| 2019 |
Smeester BA, Slipek NJ, Pomeroy EJ, Bomberger HE, Shamsan GA, Peterson JJ, Crosby MR, Draper GM, Becklin KL, Rahrmann EP, McCarthy JB, Odde DJ, Wood DK, Largaespada DA, Moriarity BS. SEMA4C is a novel target to limit osteosarcoma growth, progression, and metastasis. Oncogene. PMID 31582836 DOI: 10.1038/S41388-019-1041-X |
0.803 |
|
| 2019 |
Huang M, Tailor J, Zhen Q, Gillmor AH, Miller ML, Weishaupt H, Chen J, Zheng T, Nash EK, McHenry LK, An Z, Ye F, Takashima Y, Clarke J, Ayetey H, ... ... Moriarity BS, et al. Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis. Cell Stem Cell. PMID 31204176 DOI: 10.1016/J.Stem.2019.05.013 |
0.61 |
|
| 2019 |
Chiu AP, Tschida BR, Sham TT, Lo LH, Moriarity BS, Li XX, Lo RC, Hinton DE, Rowlands DK, Chan CO, Mok DK, Largaespada DA, Warner N, Keng VW. HBx-K130M/V131I promotes liver cancer in transgenic mice via AKT/FOXO1 signaling pathway and arachidonic acid metabolism. Molecular Cancer Research : McR. PMID 30975706 DOI: 10.1158/1541-7786.Mcr-18-1127 |
0.546 |
|
| 2019 |
Rathe SK, Popescu FE, Johnson JE, Watson AL, Marko TA, Moriarity BS, Ohlfest JR, Largaespada DA. Identification of candidate neoantigens produced by fusion transcripts in human osteosarcomas. Scientific Reports. 9: 358. PMID 30674975 DOI: 10.1038/S41598-018-36840-Z |
0.788 |
|
| 2019 |
Beckmann PJ, Larson JD, Larsson AT, Ostergaard JP, Wagner S, Rahrmann EP, Shamsan GA, Otto GM, Williams RL, Wang J, Lee C, Tschida BR, Das P, Dubuc AM, Moriarity BS, et al. Sleeping Beauty insertional mutagenesis reveals important genetic drivers of central nervous system embryonal tumors. Cancer Research. PMID 30674530 DOI: 10.1158/0008-5472.Can-18-1261 |
0.821 |
|
| 2019 |
Becklin KL, Smeester BA, Moriarity BS. Cancer Gene Discovery Utilizing Sleeping Beauty Transposon Mutagenesis. Methods in Molecular Biology (Clifton, N.J.). 1907: 161-170. PMID 30542999 DOI: 10.1007/978-1-4939-8967-6_13 |
0.403 |
|
| 2019 |
Lonetree C, Webber BR, Diers MD, Lahr WS, Kluesner M, Osborn MJ, Johnson MJ, Moriarity BS. Abstract A036: Multiplex human T-cell engineering by Cas9 base editor technology Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-A036 |
0.422 |
|
| 2018 |
Rahrmann EP, Wolf NK, Otto GM, Heltemes Harris L, Ramsey LB, Shu J, LaRue RS, Linden MA, Rathe SK, Starr TK, Farrar MA, Moriarity BS, Largaespada DA. Sleeping Beauty Screen Identifies RREB1 and Other Genetic Drivers in Human B-cell Lymphoma. Molecular Cancer Research : McR. PMID 30355676 DOI: 10.1158/1541-7786.Mcr-18-0582 |
0.809 |
|
| 2018 |
Kurata M, Wolf NK, Lahr WS, Weg MT, Kluesner MG, Lee S, Hui K, Shiraiwa M, Webber BR, Moriarity BS. Highly multiplexed genome engineering using CRISPR/Cas9 gRNA arrays. Plos One. 13: e0198714. PMID 30222773 DOI: 10.1371/Journal.Pone.0198714 |
0.332 |
|
| 2018 |
Shapovalova M, Pyper SR, Moriarity BS, LeBeau AM. The Molecular Imaging of Natural Killer Cells. Molecular Imaging. 17: 1536012118794816. PMID 30203710 DOI: 10.1177/1536012118794816 |
0.396 |
|
| 2018 |
Johnson MJ, Laoharawee K, Lahr WS, Webber BR, Moriarity BS. Engineering of Primary Human B cells with CRISPR/Cas9 Targeted Nuclease. Scientific Reports. 8: 12144. PMID 30108345 DOI: 10.1038/S41598-018-30358-0 |
0.355 |
|
| 2018 |
Li Y, Hermanson DL, Moriarity BS, Kaufman DS. Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity. Cell Stem Cell. 23: 181-192.e5. PMID 30082067 DOI: 10.1016/J.Stem.2018.06.002 |
0.391 |
|
| 2018 |
Webber B, Lonetree C, Diers M, Lahr WS, Mitchell K, Johnson MJ, Moriarity BS. Multiplex Human T Cell Engineering without Double-Strand Break Induction Using the Cas9 Base Editor System Blood. 132: 3495-3495. DOI: 10.1182/Blood-2018-99-120372 |
0.446 |
|
| 2018 |
Emily P, John H, Mitchell K, Margaret C, Bendzick L, Miller JS, Webber B, Geller MA, Felices M, Starr T, Moriarity BS. Enhancing Human NK Cell Function and Specificity for Cancer Immunotherapy Blood. 132: 2044-2044. DOI: 10.1182/Blood-2018-99-120173 |
0.4 |
|
| 2018 |
Scott M, Temiz N, Sarver A, LaRue R, Rathe S, Varshney J, Wolf N, Moriarity B, Obrien T, Spector L, Largaespada D, Modiano J, Subramanian S, Sarver A. Abstract PR14: Immune cell transcript levels, metastatic progression, and survival in osteosarcoma: A comparative transcriptome analysis Omics a Journal of Integrative Biology. 24. DOI: 10.1158/1557-3265.Sarcomas17-Pr14 |
0.795 |
|
| 2018 |
Sarver AL, Mills L, Temiz N, Scott M, Sarver A, Spector L, Wang J, Breen M, Subramanian S, Moriarity B, Modiano J, Largaespada D. Abstract 3399: Comparative genomic analyses of osteosarcoma etiology reveal a chromosomal structural rationale for the increased incidence of osteosarcoma in dogs Cancer Research. 78: 3399-3399. DOI: 10.1158/1538-7445.Am2018-3399 |
0.647 |
|
| 2018 |
Camilleri ET, Beckmann PJ, Larson JD, Kurata M, Shu J, Pope E, Hudson WA, Temiz NA, Rathe SK, LaRue RS, Sarver AE, Scott MC, Varshney J, Modiano JF, Moriarity BS, et al. Abstract 2264: RNA sequencing based analysis of transposon-induced tumors reveals novel insights into cancer pathogenesis and progression Cancer Research. 78: 2264-2264. DOI: 10.1158/1538-7445.Am2018-2264 |
0.835 |
|
| 2017 |
Kurata M, Yamamoto K, Moriarity BS, Kitagawa M, Largaespada DA. CRISPR/Cas9 library screening for drug target discovery. Journal of Human Genetics. PMID 29158600 DOI: 10.1038/S10038-017-0376-9 |
0.582 |
|
| 2017 |
Scott MC, Temiz NA, Sarver AE, LaRue RS, Rathe SK, Varshney J, Wolf NK, Moriarity BS, O'Brien TD, Spector LG, Largaespada DA, Modiano JF, Subramanian S, Sarver AL. Comparative transcriptome analysis quantifies immune cell transcript levels, metastatic progression and survival in osteosarcoma. Cancer Research. PMID 29066513 DOI: 10.1158/0008-5472.Can-17-0576 |
0.796 |
|
| 2017 |
Webber BR, O'Connor KT, McElmurry RT, Durgin EN, Eide CR, Lees CJ, Riddle MJ, Mathews WE, Frank NY, Kluth MA, Ganss C, Moriarity BS, Frank MH, Osborn MJ, Tolar J. Rapid generation of Col7a1(-/-) mouse model of recessive dystrophic epidermolysis bullosa and partial rescue via immunosuppressive dermal mesenchymal stem cells. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 28892093 DOI: 10.1038/Labinvest.2017.85 |
0.398 |
|
| 2017 |
Chaudhary R, Gryder B, Woods WS, Subramanian M, Jones MF, Li XL, Jenkins LM, Shabalina SA, Mo M, Dasso M, Yang Y, Wakefield LM, Zhu Y, Frier SM, Moriarity BS, et al. Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3. Elife. 6. PMID 28580901 DOI: 10.7554/Elife.23244 |
0.382 |
|
| 2017 |
Dorr CR, Remmel RP, Muthusamy A, Fisher J, Moriarity B, Yasuda K, Wu B, Guan W, Schuetz EG, Oetting WS, Jacobson PA, Israni AK. CRISPR/Cas9 genetic modification of CYP3A5 *3 in HuH-7 human hepatocyte cell line leads to cell lines with increased midazolam and tacrolimus metabolism. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 28533324 DOI: 10.1124/Dmd.117.076307 |
0.351 |
|
| 2017 |
Patrinostro X, O'Rourke AR, Chamberlain CM, Moriarity BS, Perrin BJ, Ervasti JM. Relative importance of βcyto- and γcyto-actin in primary mouse embryonic fibroblasts. Molecular Biology of the Cell. PMID 28077619 DOI: 10.1091/Mbc.E16-07-0503 |
0.39 |
|
| 2017 |
Chaudhary R, Gryder B, Woods WS, Subramanian M, Jones MF, Li XL, Jenkins LM, Shabalina SA, Mo M, Dasso M, Yang Y, Wakefield LM, Zhu Y, Frier SM, Moriarity BS, et al. Author response: Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3 Elife. DOI: 10.7554/Elife.23244.076 |
0.337 |
|
| 2017 |
Li YEE, Hermanson D, Moriarity B, Bjordahl R, Mahmood S, Valamehr B, Kaufman D. Engineering Human Induced Pluripotent Stem Cells with Novel Chimeric Antigen Receptors to Generate Natural Killer (NK) Cell Cancer Immunotherapies with Targeted Anti-Tumor Activity Blood. 130: 1905-1905. DOI: 10.1182/Blood.V130.Suppl_1.1905.1905 |
0.417 |
|
| 2017 |
Huang M, Zheng T, Guo J, Sperring C, Miller M, McHenry L, Zhen Q, Moriarity B, Bronner M, Conklin B, Largaespada D, Maris J, Matthay K, Weiss W. TMOD-09. HUMAN PLURIPOTENT STEM CELL-BASED MODELS OF NEUROBLASTOMA Neuro-Oncology. 19: vi256-vi256. DOI: 10.1093/Neuonc/Nox168.1048 |
0.661 |
|
| 2016 |
Pomeroy EJ, Lee LA, Lee RD, Schirm DK, Temiz NA, Ma J, Gruber TA, Diaz-Flores E, Moriarity BS, Downing JR, Shannon KM, Largaespada DA, Eckfeldt CE. Ras oncogene-independent activation of RALB signaling is a targetable mechanism of escape from NRAS(V12) oncogene addiction in acute myeloid leukemia. Oncogene. PMID 27991934 DOI: 10.1038/Onc.2016.471 |
0.586 |
|
| 2016 |
Marko TA, Shamsan GA, Edwards EN, Hazelton PE, Rathe SK, Cornax I, Overn PR, Varshney J, Diessner BJ, Moriarity BS, O'Sullivan MG, Odde DJ, Largaespada DA. Slit-Robo GTPase-Activating Protein 2 as a metastasis suppressor in osteosarcoma. Scientific Reports. 6: 39059. PMID 27966608 DOI: 10.1038/Srep39059 |
0.803 |
|
| 2016 |
Kurata M, Rathe SK, Bailey NJ, Aumann NK, Jones JM, Veldhuijzen GW, Moriarity BS, Largaespada DA. Using genome-wide CRISPR library screening with library resistant DCK to find new sources of Ara-C drug resistance in AML. Scientific Reports. 6: 36199. PMID 27808171 DOI: 10.1038/Srep36199 |
0.747 |
|
| 2016 |
Eckfeldt CE, Pomeroy EJ, Lee RD, Hazen KS, Lee LA, Moriarity BS, Largaespada DA. RALB provides critical survival signals downstream of Ras in acute myeloid leukemia. Oncotarget. PMID 27556501 DOI: 10.18632/Oncotarget.11431 |
0.564 |
|
| 2016 |
Kebriaei P, Singh H, Huls MH, Figliola MJ, Bassett R, Olivares S, Jena B, Dawson MJ, Kumaresan PR, Su S, Maiti S, Dai J, Moriarity B, Forget MA, Senyukov V, et al. Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells. The Journal of Clinical Investigation. PMID 27482888 DOI: 10.1172/Jci86721 |
0.541 |
|
| 2016 |
Yun YS, Kim KH, Tschida B, Sachs Z, Noble-Orcutt KE, Moriarity BS, Ai T, Ding R, Williams J, Chen L, Largaespada D, Kim DH. mTORC1 Coordinates Protein Synthesis and Immunoproteasome Formation via PRAS40 to Prevent Accumulation of Protein Stress. Molecular Cell. PMID 26876939 DOI: 10.1016/J.Molcel.2016.01.013 |
0.516 |
|
| 2016 |
Hermanson DL, Moriarity B, Argall T, Geller MA, Largaespada D, Kaufman DS. Abstract A175: Design and evaluation of novel natural killer cell chimeric antigen receptors Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-A175 |
0.588 |
|
| 2016 |
Wolf N, Smeester B, Weg M, Largaespada DA, Moriarity BS. Abstract A36: Validation of candidate cancer genes using the CRISPR system Cancer Research. 76. DOI: 10.1158/1538-7445.Pedca15-A36 |
0.675 |
|
| 2016 |
Smeester B, Wolf N, Moriarity BS. Abstract 64: Identification and validation of novel therapeutic targets of osteosarcoma using cutting edge technologies Cancer Research. 76: 64-64. DOI: 10.1158/1538-7445.Am2016-64 |
0.543 |
|
| 2016 |
Zuckermann M, Hovestadt V, Knobbe-Thomsen CB, Zapatka M, Northcott PA, Schramm K, Belic J, Jones DT, Tschida B, Moriarity B, Largaespada D, Roussel MF, Korshunov A, Reifenberger G, Pfister SM, et al. PCM-15SOMATIC CRISPR/Cas9-MEDIATED TUMOR SUPPRESSOR DISRUPTION ENABLES VERSATILE BRAIN TUMOR MODELING Neuro-Oncology. 18: iii142.2-iii142. DOI: 10.1093/Neuonc/Now080.15 |
0.571 |
|
| 2015 |
Wolf NK, Largaespada DA, Moriarity BS. Coping with cancer genes altered by copy number. Oncotarget. 6: 35155-6. PMID 26577648 DOI: 10.18632/Oncotarget.6215 |
0.633 |
|
| 2015 |
Chiu AP, Tschida BR, Lo LH, Moriarity BS, Rowlands DK, Largaespada DA, Keng VW. Transposon mouse models to elucidate the genetic mechanisms of hepatitis B viral induced hepatocellular carcinoma. World Journal of Gastroenterology. 21: 12157-70. PMID 26576100 DOI: 10.3748/Wjg.V21.I42.12157 |
0.529 |
|
| 2015 |
Temiz NA, Moriarity BS, Wolf NK, Riordan JD, Dupuy AJ, Largaespada DA, Sarver AL. RNA sequencing of Sleeping Beauty transposon-induced tumors detect transposon-RNA fusions allowing precision analyses of forward genetic cancer screens. Genome Research. PMID 26553456 DOI: 10.1101/Gr.188649.114 |
0.59 |
|
| 2015 |
Mirabello L, Koster R, Moriarity BS, Spector LG, Meltzer PS, Gary J, Machiela MJ, Pankratz N, Panagiotou OA, Largaespada D, Wang Z, Gastier-Foster JM, Gorlick R, Khanna C, Caminada de Toledo SR, et al. A genome-wide scan identifies variants in NFIB associated with metastasis in patients with osteosarcoma. Cancer Discovery. PMID 26084801 DOI: 10.1158/2159-8290.Cd-15-0125 |
0.564 |
|
| 2015 |
Zuckermann M, Hovestadt V, Knobbe-Thomsen CB, Zapatka M, Northcott PA, Schramm K, Belic J, Jones DT, Tschida B, Moriarity B, Largaespada D, Roussel MF, Korshunov A, Reifenberger G, Pfister SM, et al. Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling. Nature Communications. 6: 7391. PMID 26067104 DOI: 10.1038/Ncomms8391 |
0.607 |
|
| 2015 |
Moriarity BS, Largaespada DA. Sleeping Beauty transposon insertional mutagenesis based mouse models for cancer gene discovery. Current Opinion in Genetics & Development. 30: 66-72. PMID 26051241 DOI: 10.1016/J.Gde.2015.04.007 |
0.642 |
|
| 2015 |
Moriarity BS, Otto GM, Rahrmann EP, Rathe SK, Wolf NK, Weg MT, Manlove LA, LaRue RS, Temiz NA, Molyneux SD, Choi K, Holly KJ, Sarver AL, Scott MC, Forster CL, et al. A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis. Nature Genetics. 47: 615-24. PMID 25961939 DOI: 10.1038/Ng.3293 |
0.815 |
|
| 2015 |
Zuckermann M, Hovestadt V, Knobbe-Thomsen CB, Zapatka M, Northcott PA, Schramm K, Belic J, Jones DTW, Tschida B, Moriarity B, Largaespada D, Roussel MF, Korshunov A, Reifenberger G, Pfister SM, et al. Abstract PR02: Somatic CRISPR/Cas9-mediated tumor suppressor disruption enables versatile brain tumor modeling Brain. 75. DOI: 10.1158/1538-7445.Brain15-Pr02 |
0.665 |
|
| 2015 |
Huang M, McHenry LK, Miller ML, Kim GE, Moriarity BS, Miyaoka Y, Bronner ME, Largaespada DA, Conklin BR, Ji HP, Maris JM, Matthay KK, Weiss WA. Abstract 3230: Human stem cell-based model of MYCN-driven neuroblastoma Cancer Research. 75: 3230-3230. DOI: 10.1158/1538-7445.Am2015-3230 |
0.649 |
|
| 2015 |
Das P, Jackson P, Moriarity B, Rahrmann E, LaRue R, Largaespada D. PTPS-02FOXR2: AN ONCOGENE IN MEDULLOBLASTOMA Neuro-Oncology. 17: v179.2-v179. DOI: 10.1093/Neuonc/Nov228.02 |
0.811 |
|
| 2014 |
Rathe SK, Moriarity BS, Stoltenberg CB, Kurata M, Aumann NK, Rahrmann EP, Bailey NJ, Melrose EG, Beckmann DA, Liska CR, Largaespada DA. Using RNA-seq and targeted nucleases to identify mechanisms of drug resistance in acute myeloid leukemia. Scientific Reports. 4: 6048. PMID 25116387 DOI: 10.1038/Srep06048 |
0.784 |
|
| 2014 |
Tseng YY, Moriarity BS, Gong W, Akiyama R, Tiwari A, Kawakami H, Ronning P, Reuland B, Guenther K, Beadnell TC, Essig J, Otto GM, O'Sullivan MG, Largaespada DA, Schwertfeger KL, et al. PVT1 dependence in cancer with MYC copy-number increase. Nature. 512: 82-6. PMID 25043044 DOI: 10.1038/Nature13311 |
0.588 |
|
| 2014 |
Li MV, Shukla D, Rhodes BH, Lall A, Shu J, Moriarity BS, Largaespada DA. HomeRun Vector Assembly System: a flexible and standardized cloning system for assembly of multi-modular DNA constructs. Plos One. 9: e100948. PMID 24959875 DOI: 10.1371/Journal.Pone.0100948 |
0.493 |
|
| 2014 |
Rahrmann EP, Moriarity BS, Otto GM, Watson AL, Choi K, Collins MH, Wallace M, Webber BR, Forster CL, Rizzardi AE, Schmechel SC, Ratner N, Largaespada DA. Trp53 haploinsufficiency modifies EGFR-driven peripheral nerve sheath tumorigenesis. The American Journal of Pathology. 184: 2082-98. PMID 24832557 DOI: 10.1016/J.Ajpath.2014.04.006 |
0.823 |
|
| 2014 |
Moriarity BS, Rahrmann EP, Beckmann DA, Conboy CB, Watson AL, Carlson DF, Olson ER, Hyland KA, Fahrenkrug SC, McIvor RS, Largaespada DA. Simple and efficient methods for enrichment and isolation of endonuclease modified cells. Plos One. 9: e96114. PMID 24798371 DOI: 10.1371/Journal.Pone.0096114 |
0.8 |
|
| 2014 |
Eckfeldt CE, Pomeroy EJ, Lee RD, Hazen KS, Moriarity BS, Largaespada DA. Ras Effector Pathways Differentially Support Proliferation and Survival of Acute Myeloid Leukemia Blood. 124: 3755-3755. DOI: 10.1182/Blood.V124.21.3755.3755 |
0.582 |
|
| 2014 |
Keng VW, Tschida BR, Kuka TP, Moriarity BS, Bell JB, Largaespada DA. Abstract 929: Identification of ZBTB20 as a novel oncogene associated with the gender bias occurrence of hepatocellular carcinoma Cancer Research. 74: 929-929. DOI: 10.1158/1538-7445.Am2014-929 |
0.598 |
|
| 2014 |
Jackson P, Das P, Larson J, Moriarity B, Largaespada D. PM-05 * ARHGAP36 AS A NOVEL DRIVER IN HIGH-RISK HUMAN MEDULLOBLASTOMA Neuro-Oncology. 16: v170-v170. DOI: 10.1093/Neuonc/Nou268.5 |
0.755 |
|
| 2013 |
Rahrmann EP, Watson AL, Keng VW, Choi K, Moriarity BS, Beckmann DA, Wolf NK, Sarver A, Collins MH, Moertel CL, Wallace MR, Gel B, Serra E, Ratner N, Largaespada DA. Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis. Nature Genetics. 45: 756-66. PMID 23685747 DOI: 10.1038/Ng.2641 |
0.823 |
|
| 2013 |
Watson AL, Rahrmann EP, Moriarity BS, Choi K, Conboy CB, Greeley AD, Halfond AL, Anderson LK, Wahl BR, Keng VW, Rizzardi AE, Forster CL, Collins MH, Sarver AL, Wallace MR, et al. Canonical Wnt/β-catenin signaling drives human schwann cell transformation, progression, and tumor maintenance. Cancer Discovery. 3: 674-89. PMID 23535903 DOI: 10.1158/2159-8290.Cd-13-0081 |
0.824 |
|
| 2013 |
Moriarity BS, Rahrmann EP, Keng VW, Manlove LS, Beckmann DA, Wolf NK, Khurshid T, Bell JB, Largaespada DA. Modular assembly of transposon integratable multigene vectors using RecWay assembly. Nucleic Acids Research. 41: e92. PMID 23444141 DOI: 10.1093/Nar/Gkt115 |
0.765 |
|
| 2013 |
Keng VW, Sia D, Sarver AL, Tschida BR, Fan D, Alsinet C, Solé M, Lee WL, Kuka TP, Moriarity BS, Villanueva A, Dupuy AJ, Riordan JD, Bell JB, Silverstein KA, et al. Sex bias occurrence of hepatocellular carcinoma in Poly7 molecular subclass is associated with EGFR. Hepatology (Baltimore, Md.). 57: 120-30. PMID 22899566 DOI: 10.1002/Hep.26004 |
0.564 |
|
| 2013 |
Powell TA, Moriarity BS, Sarver AL, Largaespada DA. Abstract C3: Candidate osteosarcoma metastatic drivers identified in highly clonal metastases using transposon-mediated insertional mutagenesis Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-C3 |
0.675 |
|
| 2013 |
Keng VW, Watson AL, Rahrmann EP, Li H, Tschida BR, Moriarity BS, Choi K, Rizvi TA, Collins MH, Wallace MR, Ratner N, Largaespada DA. Abstract 354: Conditional inactivation of Pten and overexpression of EGFR in Schwann cells results in early high-grade peripheral nerve sheath tumor development. Cancer Research. 73: 354-354. DOI: 10.1158/1538-7445.Am2013-354 |
0.815 |
|
| 2013 |
Agarwal M, Nitta R, Dovat S, Li G, Arita H, Narita Y, Fukushima S, Tateishi K, Matsushita Y, Yoshida A, Miyakita Y, Ohno M, Collins VP, Kawahara N, Shibui S, ... ... Moriarity BS, et al. CELL BIOLOGY AND SIGNALING Neuro-Oncology. 15: iii12-iii31. DOI: 10.1093/Neuonc/Not174 |
0.674 |
|
| 2012 |
Keng VW, Watson AL, Rahrmann EP, Li H, Tschida BR, Moriarity BS, Choi K, Rizvi TA, Collins MH, Wallace MR, Ratner N, Largaespada DA. Conditional Inactivation of Pten with EGFR Overexpression in Schwann Cells Models Sporadic MPNST. Sarcoma. 2012: 620834. PMID 23319880 DOI: 10.1155/2012/620834 |
0.816 |
|
| 2012 |
Shu J, Li L, Moriarity B, Thayanithy V, Spector LG, Largaespada DA, Steer CJ, Subramanian S. Abstract 4042: Loss of imprinting at the 14q32 locus contributes to osteosarcoma Cancer Research. 72: 4042-4042. DOI: 10.1158/1538-7445.Am2012-4042 |
0.583 |
|
| 2012 |
Ang S, Maiti S, Moriarity B, Andrews K, Ossowski M, Tzeng K, Talbot R, Kellar D, Huls H, Kebriaei P, Kelly S, Shpall E, Largaespada D, Champlin R, Hackett P, et al. Assessing Sleeping Beauty Transpositions for T-Cell Immunotherapy by Supercomputer-Based High-Throughput Profiling of Integration Events Biology of Blood and Marrow Transplantation. 18: S219. DOI: 10.1016/J.Bbmt.2011.12.046 |
0.523 |
|
| 2011 |
Moriarity B, Largaespada DA. A Comprehensive Guide to Sleeping Beauty-Based Somatic Transposon Mutagenesis in the Mouse. Current Protocols in Mouse Biology. 1: 347-68. PMID 26069058 DOI: 10.1002/9780470942390.Mo110087 |
0.597 |
|
| 2011 |
Wilber A, Ulloa Montoya F, Hammer L, Moriarity BS, Geurts AM, Largaespada DA, Verfaillie CM, McIvor RS, Lakshmipathy U. Efficient non-viral integration and stable gene expression in multipotent adult progenitor cells. Stem Cells International. 2011: 717069. PMID 21977042 DOI: 10.4061/2011/717069 |
0.694 |
|
| 2011 |
Ang SO, Maiti S, Moriarity B, Ossowski M, Andrews K, Tzeng K, Talbot R, Kellar D, Huls H, Kebriaei P, Largaespada DA, Champlin R, Hackett P, Cooper LJN. Assessing Potential Genotoxicity of Sleeping Beauty Transposition Events in T-Cell Immunotherapy by Supercomputer-Based High Throughput Profiling, Blood. 118: 4174-4174. DOI: 10.1182/Blood.V118.21.4174.4174 |
0.585 |
|
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