Nicholas H. Oberlies, Ph.D. - Publications

Affiliations: 
1997-1998 Agrochemicals American Cyanamid Company 
 1998-2008 Natural Products Research Triangle Institute 
 2009- Chemistry and Biochemistry UNC Greensboro, Greensboro, NC, United States 
Area:
Organic chemistry, biochemistry, natural products
Website:
https://chem.uncg.edu/oberlies/

211 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Steenwyk JL, Balamurugan C, Raja HA, Gonçalves C, Li N, Martin F, Berman J, Oberlies NH, Gibbons JG, Goldman GH, Geiser DM, Houbraken J, Hibbett DS, Rokas A. Phylogenomics reveals extensive misidentification of fungal strains from the genus . Microbiology Spectrum. e0398023. PMID 38445873 DOI: 10.1128/spectrum.03980-23  0.44
2024 Kuttikrishnan S, Hasan M, Prabhu KS, El-Elimat T, Oberlies NH, Pearce CJ, Alali FQ, Ahmad A, Pourkarimi E, Bhat AA, Yalcin HC, Uddin S. Exploring the in vivo anti-cancer potential of Neosetophomone B in leukemic cells using a zebrafish xenograft model. Experimental Cell Research. 435: 113907. PMID 38184222 DOI: 10.1016/j.yexcr.2023.113907  0.711
2023 Kuttikrishnan S, Ahmad F, Mateo JM, Prabhu KS, El-Elimat T, Oberlies NH, Pearce CJ, Akil ASA, Bhat AA, Alali FQ, Uddin S. Neosetophomone B induces apoptosis in multiple myeloma cells via targeting of AKT/SKP2 signaling pathway. Cell Biology International. PMID 37885161 DOI: 10.1002/cbin.12101  0.715
2023 Kuttikrishnan S, Masoodi T, Ahmad F, Sher G, Prabhu KS, Mateo JM, Buddenkotte J, El-Elimat T, Oberlies NH, Pearce CJ, Bhat AA, Alali FQ, Steinhoff M, Uddin S. In vitro evaluation of Neosetophomone B inducing apoptosis in cutaneous T cell lymphoma by targeting the FOXM1 signaling pathway. Journal of Dermatological Science. PMID 37865581 DOI: 10.1016/j.jdermsci.2023.10.001  0.69
2023 Steenwyk JL, Knowles S, Bastos RW, Balamurugan C, Rinker D, Mead ME, Roberts CD, Raja HA, Li Y, Colabardini AC, de Castro PA, Dos Reis TF, Canóvas D, Sanchez RL, Lagrou K, ... ... Oberlies NH, et al. Evolutionary origin, population diversity, and diagnostics for a cryptic hybrid pathogen. Biorxiv : the Preprint Server For Biology. PMID 37461539 DOI: 10.1101/2023.07.03.547508  0.484
2022 Hatmaker EA, Rangel-Grimaldo M, Raja HA, Pourhadi H, Knowles SL, Fuller K, Adams EM, Lightfoot JD, Bastos RW, Goldman GH, Oberlies NH, Rokas A. Genomic and Phenotypic Trait Variation of the Opportunistic Human Pathogen Aspergillus flavus and Its Close Relatives. Microbiology Spectrum. e0306922. PMID 36318036 DOI: 10.1128/spectrum.03069-22  0.46
2022 El-Elimat T, Al-Qiam R, Burdette JE, Al Sharie AH, Al-Gharaibeh M, Oberlies NH. Homoisoflavonoids from the bulbs of Bellevalia longipes and an assessment of their potential cytotoxic activity. Phytochemistry. 113343. PMID 35963294 DOI: 10.1016/j.phytochem.2022.113343  0.579
2022 Kuttikrishnan S, Masoodi T, Sher G, Bhat AA, Patil K, El-Elimat T, Oberlies NH, Pearce CJ, Haris M, Ahmad A, Alali FQ, Uddin S. Bioinformatics Analysis Reveals FOXM1/BUB1B Signaling Pathway as a Key Target of Neosetophomone B in Human Leukemic Cells: A Gene Network-Based Microarray Analysis. Frontiers in Oncology. 12: 929996. PMID 35847923 DOI: 10.3389/fonc.2022.929996  0.709
2022 Kuttikrishnan S, Bhat AA, Mateo JM, Ahmad F, Alali FQ, El-Elimat T, Oberlies NH, Pearce CJ, Uddin S. Anticancer activity of Neosetophomone B by targeting AKT/SKP2/MTH1 axis in leukemic cells. Biochemical and Biophysical Research Communications. 601: 59-64. PMID 35228122 DOI: 10.1016/j.bbrc.2022.02.071  0.701
2022 de Castro PA, Colabardini AC, Moraes M, Horta MAC, Knowles SL, Raja HA, Oberlies NH, Koyama Y, Ogawa M, Gomi K, Steenwyk JL, Rokas A, Gonçales RA, Duarte-Oliveira C, Carvalho A, et al. Regulation of gliotoxin biosynthesis and protection in Aspergillus species. Plos Genetics. 18: e1009965. PMID 35041649 DOI: 10.1371/journal.pgen.1009965  0.464
2022 Flores-Bocanegra L, Al Subeh ZY, Egan JM, El-Elimat T, Raja HA, Burdette JE, Pearce CJ, Linington RG, Oberlies NH. Dereplication of Fungal Metabolites by NMR-Based Compound Networking Using MADByTE. Journal of Natural Products. PMID 35020372 DOI: 10.1021/acs.jnatprod.1c00841  0.81
2021 Kuttikrishnan S, Prabhu KS, Al Sharie AH, Al Zu'bi YO, Alali FQ, Oberlies NH, Ahmad A, El-Elimat T, Uddin S. Natural resorcylic acid lactones: A chemical biology approach for anticancer activity. Drug Discovery Today. PMID 34655796 DOI: 10.1016/j.drudis.2021.10.001  0.728
2021 El-Elimat T, Figueroa M, Raja HA, Alnabulsi SM, Oberlies NH. Coumarins, dihydroisocoumarins, a dibenzo--pyrone, a meroterpenoid, and a merodrimane from . Tetrahedron Letters. 72. PMID 34421136 DOI: 10.1016/j.tetlet.2021.153067  0.641
2021 Steenwyk JL, Mead ME, de Castro PA, Valero C, Damasio A, Dos Santos RAC, Labella AL, Li Y, Knowles SL, Raja HA, Oberlies NH, Zhou X, Cornely OA, Fuchs F, Koehler P, et al. Genomic and Phenotypic Analysis of COVID-19-Associated Pulmonary Aspergillosis Isolates of Aspergillus fumigatus. Microbiology Spectrum. e0001021. PMID 34106569 DOI: 10.1128/Spectrum.00010-21  0.475
2021 El-Elimat T, Raja HA, Figueroa M, Al Sharie AH, Bunch RL, Oberlies NH. Freshwater Fungi as a Source of Chemical Diversity: A Review. Journal of Natural Products. PMID 33662206 DOI: 10.1021/acs.jnatprod.0c01340  0.598
2021 Khin M, Knowles SL, Crandall WJ, Jones DD, Oberlies NH, Cech NB, Houriet J. Capturing the antimicrobial profile of Rosmarinus officinalis against methicillin-resistant Staphylococcus aureus (MRSA) with bioassay-guided fractionation and bioinformatics. Journal of Pharmaceutical and Biomedical Analysis. 197: 113965. PMID 33640687 DOI: 10.1016/j.jpba.2021.113965  0.319
2020 Al Subeh ZY, Raja HA, Monro S, Flores-Bocanegra L, El-Elimat T, Pearce CJ, McFarland SA, Oberlies NH. Correction to Enhanced Production and Anticancer Properties of Photoactivated Perylenequinones. Journal of Natural Products. PMID 33314937 DOI: 10.1021/acs.jnatprod.0c01289  0.55
2020 Steenwyk JL, Mead ME, de Castro PA, Valero C, Damasio A, Dos Santos RAC, Labella AL, Li Y, Knowles SL, Raja HA, Oberlies NH, Zhou X, Cornely OA, Fuchs F, Koehler P, et al. Genomic and phenotypic analysis of COVID-19-associated pulmonary aspergillosis isolates of . Biorxiv : the Preprint Server For Biology. PMID 33173866 DOI: 10.1101/2020.11.06.371971  0.475
2020 Ricigliano VA, Sica VP, Knowles SL, Diette N, Howarth DG, Oberlies NH. Bioactive diterpenoid metabolism and cytotoxic activities of genetically transformed Euphorbia lathyris roots. Phytochemistry. 179: 112504. PMID 32980713 DOI: 10.1016/j.phytochem.2020.112504  0.762
2020 El-Elimat T, Alhawarri MB, Rivera-Chávez J, Burdette JE, Czarnecki A, Al-Gharaibeh M, Al Sharie AH, Alhusban A, Alali FQ, Oberlies NH. Phenethyisoquinoline alkaloids from the leaves of Androcymbium palaestinum. Fitoterapia. 146: 104706. PMID 32829012 DOI: 10.1016/J.Fitote.2020.104706  0.772
2020 Steenwyk JL, Mead ME, Knowles SL, Raja HA, Roberts CD, Bader O, Houbraken J, Goldman GH, Oberlies NH, Rokas A. Variation Among Biosynthetic Gene Clusters, Secondary Metabolite Profiles, and Cards of Virulence Across Species. Genetics. PMID 32817009 DOI: 10.1534/Genetics.120.303549  0.531
2020 Al Subeh ZY, Raja HA, Monro S, Flores-Bocanegra L, El-Elimat T, Pearce CJ, McFarland SA, Oberlies NH. Enhanced Production and Anticancer Properties of Photoactivated Perylenequinones. Journal of Natural Products. PMID 32786877 DOI: 10.1021/Acs.Jnatprod.0C00492  0.654
2020 Flores-Bocanegra L, Raja HA, Graf TN, Augustinović M, Wallace ED, Hematian S, Kellogg JJ, Todd DA, Cech NB, Oberlies NH. The Chemistry of Kratom []: Updated Characterization Data and Methods to Elucidate Indole and Oxindole Alkaloids. Journal of Natural Products. PMID 32597657 DOI: 10.1021/Acs.Jnatprod.0C00257  0.328
2020 Steenwyk JL, Lind AL, Ries LNA, Dos Reis TF, Silva LP, Almeida F, Bastos RW, Fraga da Silva TFC, Bonato VLD, Pessoni AM, Rodrigues F, Raja HA, Knowles SL, Oberlies NH, Lagrou K, et al. Pathogenic Allodiploid Hybrids of Aspergillus Fungi. Current Biology : Cb. PMID 32502407 DOI: 10.1016/J.Cub.2020.04.071  0.535
2020 Graf TN, Kao D, Rivera-Chávez J, Gallagher JM, Raja HA, Oberlies NH. Drug Leads from Endophytic Fungi: Lessons Learned via Scaled Production. Planta Medica. PMID 32219776 DOI: 10.1055/A-1130-4856  0.375
2020 Rokas A, Mead ME, Steenwyk JL, Oberlies NH, Goldman GH. Evolving moldy murderers: Aspergillus section Fumigati as a model for studying the repeated evolution of fungal pathogenicity. Plos Pathogens. 16: e1008315. PMID 32106242 DOI: 10.1371/Journal.Ppat.1008315  0.485
2020 Knowles SL, Raja HA, Isawi IH, Flores-Bocanegra L, Reggio PH, Pearce CJ, Burdette JE, Rokas A, Oberlies NH. Wheldone: Characterization of a Unique Scaffold from the Coculture of and . Organic Letters. PMID 32096649 DOI: 10.1021/Acs.Orglett.0C00219  0.591
2020 Knowles SL, Mead ME, Silva LP, Raja HA, Steenwyk JL, Goldman GH, Oberlies NH, Rokas A. Gliotoxin, a Known Virulence Factor in the Major Human Pathogen Aspergillus fumigatus, Is Also Biosynthesized by Its Nonpathogenic Relative . Mbio. 11. PMID 32047138 DOI: 10.1128/Mbio.03361-19  0.553
2020 Kao D, Flores-Bocanegra L, Raja HA, Darveaux BA, Pearce CJ, Oberlies NH. New tricks for old dogs: Two new macrocyclic trichothecene epimers and absolute configuration of 16-hydroxyverrucarin B. Phytochemistry. 172: 112238. PMID 31931448 DOI: 10.1016/J.Phytochem.2019.112238  0.365
2020 Salvi A, Amrine CSM, Austin JR, Kilpatrick K, Russo A, Lantvit D, Calderon-Gierszal E, Mattes Z, Pearce CJ, Grinstaff MW, Colby AH, Oberlies NH, Burdette JE. Verticillin A Causes Apoptosis and Reduces Tumor Burden in High-Grade Serous Ovarian Cancer by Inducing DNA Damage. Molecular Cancer Therapeutics. 19: 89-100. PMID 31909733 DOI: 10.1158/1535-7163.Mct-19-0205  0.323
2020 Rokas A, Mead ME, Steenwyk JL, Raja HA, Oberlies NH. Biosynthetic gene clusters and the evolution of fungal chemodiversity. Natural Product Reports. PMID 31898704 DOI: 10.1039/C9Np00045C  0.51
2019 Aparicio-Cuevas MA, González MDC, Raja H, Rivero-Cruz I, Kurina SJ, Burdette JE, Oberlies NH, Figueroa M. Metabolites from the Marine-Facultative sp. MEXU 27854 and MEXU 29901 from Caleta Bay, Mexico. Tetrahedron Letters. 60: 1649-1652. PMID 32390667 DOI: 10.1016/J.Tetlet.2019.05.037  0.365
2019 Knowles SL, Vu N, Todd DA, Raja HA, Rokas A, Zhang Q, Oberlies NH. Orthogonal Method for Double-Bond Placement via Ozone-Induced Dissociation Mass Spectrometry (OzID-MS). Journal of Natural Products. PMID 31823607 DOI: 10.1021/Acs.Jnatprod.9B00787  0.56
2019 Amrine CSM, Long JL, Raja HA, Kurina SJ, Burdette JE, Pearce CJ, Oberlies NH. Engineering Fluorine into Verticillins (Epipolythiodioxopiperazine Alkaloids) via Precursor-Directed Biosynthesis. Journal of Natural Products. PMID 31633350 DOI: 10.1021/Acs.Jnatprod.9B00711  0.347
2019 Rivera-Chávez J, Caesar L, Garcia-Salazar JJ, Raja HA, Cech NB, Pearce CJ, Oberlies NH. Mycopyranone: a 8,8'-binaphthopyranone with potent anti-MRSA activity from the fungus sp. Tetrahedron Letters. 60: 594-597. PMID 31598014 DOI: 10.1016/J.Tetlet.2019.01.029  0.363
2019 Mead ME, Raja HA, Steenwyk JL, Knowles SL, Oberlies NH, Rokas A. Draft Genome Sequence of the Griseofulvin-Producing Fungus Xylaria flabelliformis Strain G536. Microbiology Resource Announcements. 8. PMID 31537670 DOI: 10.1128/MRA.00890-19  0.419
2019 Oberlies NH, Knowles SL, Amrine CSM, Kao D, Kertesz V, Raja HA. Droplet probe: coupling chromatography to the in situ evaluation of the chemistry of nature. Natural Product Reports. PMID 31112181 DOI: 10.1039/C9Np00019D  0.365
2019 Parlet CP, Kavanaugh JS, Crosby HA, Raja HA, El-Elimat T, Todd DA, Pearce CJ, Cech NB, Oberlies NH, Horswill AR. Apicidin Attenuates MRSA Virulence through Quorum-Sensing Inhibition and Enhanced Host Defense. Cell Reports. 27: 187-198.e6. PMID 30943400 DOI: 10.1016/J.Celrep.2019.03.018  0.609
2019 Prabhu KS, Siveen KS, Kuttikrishnan S, Jochebeth A, Ali TA, Elareer NR, Iskandarani A, Quaiyoom Khan A, Merhi M, Dermime S, El-Elimat T, Oberlies NH, Alali FQ, Steinhoff M, Uddin S. Greensporone A, a Fungal Secondary Metabolite Suppressed Constitutively Activated AKT via ROS Generation and Induced Apoptosis in Leukemic Cell Lines. Biomolecules. 9. PMID 30934922 DOI: 10.3390/biom9040126  0.709
2019 Knowles SL, Raja HA, Wright AJ, Lee AML, Caesar LK, Cech NB, Mead ME, Steenwyk JL, Ries LNA, Goldman GH, Rokas A, Oberlies NH. Mapping the Fungal Battlefield: Using Chemistry and Deletion Mutants to Monitor Interspecific Chemical Interactions Between Fungi. Frontiers in Microbiology. 10: 285. PMID 30837981 DOI: 10.3389/Fmicb.2019.00285  0.58
2019 Mead ME, Knowles SL, Raja HA, Beattie SR, Kowalski CH, Steenwyk JL, Silva LP, Chiaratto J, Ries LNA, Goldman GH, Cramer RA, Oberlies NH, Rokas A. Characterizing the Pathogenic, Genomic, and Chemical Traits of , a Close Relative of the Major Human Fungal Pathogen . Msphere. 4. PMID 30787113 DOI: 10.1128/mSphere.00018-19  0.506
2019 Paguigan ND, Rivera-Chávez J, Stempin JJ, Augustinović M, Noras AI, Raja HA, Todd DA, Triplett KD, Day C, Figueroa M, Hall PR, Cech NB, Oberlies NH. Prenylated Diresorcinols Inhibit Bacterial Quorum Sensing. Journal of Natural Products. PMID 30730742 DOI: 10.1021/Acs.Jnatprod.8B00925  0.786
2019 Kellogg JJ, Paine MF, McCune JS, Oberlies NH, Cech NB. Selection and characterization of botanical natural products for research studies: a NaPDI center recommended approach. Natural Product Reports. PMID 30681109 DOI: 10.1039/C8Np00065D  0.327
2019 El-Elimat T, Raja HA, Ayers S, Kurina SJ, Burdette JE, Mattes Z, Sabatelle R, Bacon JW, Colby AH, Grinstaff MW, Pearce CJ, Oberlies NH. Meroterpenoids from Neosetophoma sp.: A Dioxa[4.3.3]propellane Ring System, Potent Cytotoxicity, and Prolific Expression. Organic Letters. PMID 30620608 DOI: 10.1021/Acs.Orglett.8B03769  0.636
2019 Kandagatla SK, Uhl RT, Graf TN, Oberlies NH, Raner GM. Pheophorbide Derivatives Isolated From Açaí Berries (Euterpea oleracea) Activate an Antioxidant Response Element In Vitro Natural Product Communications. 14: 1934578X1985244. DOI: 10.1177/1934578X19852443  0.308
2018 Kao D, Henkin JM, Soejarto DD, Kinghorn AD, Oberlies NH. Non-Destructive Chemical Analysis of a L. (Mangosteen) Herbarium Voucher Specimen. Phytochemistry Letters. 28: 124-129. PMID 30613309 DOI: 10.1016/J.Phytol.2018.10.001  0.333
2018 McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, ... ... Oberlies NH, et al. Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. Natural Product Reports. PMID 30468235 DOI: 10.1039/c8np90041h  0.753
2018 Amrine CSM, Raja HA, Darveaux BA, Pearce CJ, Oberlies NH. Media studies to enhance the production of verticillins facilitated by in situ chemical analysis. Journal of Industrial Microbiology & Biotechnology. PMID 30259213 DOI: 10.1007/S10295-018-2083-8  0.359
2018 Crnkovic CM, Krunic A, May DS, Wilson TA, Kao D, Burdette JE, Fuchs JR, Oberlies NH, Orjala J. Calothrixamides A and B from the Cultured Cyanobacterium Calothrix sp. UIC 10520. Journal of Natural Products. PMID 30192537 DOI: 10.1021/Acs.Jnatprod.8B00432  0.428
2018 El-Elimat T, Alzoubi KH, AbuAlSamen MM, Al Subeh ZY, Graf TN, Oberlies NH. Silymarin Prevents Memory Impairments, Anxiety, and Depressive-Like Symptoms in a Rat Model of Post-Traumatic Stress Disorder. Planta Medica. PMID 30153692 DOI: 10.1055/A-0710-5673  0.562
2018 Prabhu KS, Siveen KS, Kuttikrishnan S, Iskandarani AN, Khan AQ, Merhi M, Omri HE, Dermime S, El-Elimat T, Oberlies NH, Alali FQ, Uddin S. Greensporone C, a Freshwater Fungal Secondary Metabolite Induces Mitochondrial-Mediated Apoptotic Cell Death in Leukemic Cell Lines. Frontiers in Pharmacology. 9: 720. PMID 30061828 DOI: 10.3389/Fphar.2018.00720  0.741
2018 Wallace ED, Oberlies NH, Cech NB, Kellogg JJ. Detection of adulteration in Hydrastis canadensis (goldenseal) dietary supplements via untargeted mass spectrometry-based metabolomics. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. PMID 30031041 DOI: 10.1016/J.Fct.2018.07.033  0.341
2018 Rivera-Chávez J, El-Elimat T, Gallagher JM, Graf TN, Fournier J, Panigrahi GK, Deep G, Bunch RL, Raja HA, Oberlies NH. Delitpyrones: α-Pyrone Derivatives from a Freshwater Delitschia sp. Planta Medica. PMID 30016827 DOI: 10.1055/A-0654-5850  0.658
2018 McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, ... ... Oberlies NH, et al. The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. Natural Product Reports. PMID 30003207 DOI: 10.1039/C7Np00064B  0.766
2018 El-Elimat T, Rivera-Chávez J, Burdette JE, Czarnecki A, Alhawarri MB, Al-Gharaibeh M, Alali F, Oberlies NH. Cytotoxic homoisoflavonoids from the bulbs of Bellevalia flexuosa. Fitoterapia. PMID 29471027 DOI: 10.1016/J.Fitote.2018.02.022  0.753
2018 Tian DD, Kellogg JJ, Okut N, Oberlies NH, Cech NB, Shen DD, McCune JS, Paine MF. Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea () Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 29467215 DOI: 10.1124/Dmd.117.079491  0.337
2017 Rivera-Chávez J, Raja HA, Graf TN, Gallagher JM, Metri P, Xue D, Pearce CJ, Oberlies NH. Prealamethicin F50 and related peptaibols from Trichoderma arundinaceum: Validation of their authenticity via in situ chemical analysis. Rsc Advances. 7: 45733-45751. PMID 29379602 DOI: 10.1039/C7Ra09602J  0.44
2017 Paguigan ND, Al-Huniti MH, Raja HA, Czarnecki A, Burdette JE, González-Medina M, Medina-Franco JL, Polyak SJ, Pearce CJ, Croatt MP, Oberlies NH. Chemoselective fluorination and chemoinformatic analysis of griseofulvin: Natural vs fluorinated fungal metabolites. Bioorganic & Medicinal Chemistry. PMID 28802670 DOI: 10.1016/J.Bmc.2017.07.041  0.798
2017 Kellogg JJ, Wallace ED, Graf TN, Oberlies NH, Cech NB. Conventional and accelerated-solvent extractions of green tea (camellia sinensis) for metabolomics-based chemometrics. Journal of Pharmaceutical and Biomedical Analysis. 145: 604-610. PMID 28787673 DOI: 10.1016/J.Jpba.2017.07.027  0.3
2017 Sica VP, Rees ER, Raja HA, Rivera-Chávez J, Burdette JE, Pearce CJ, Oberlies NH. In situ mass spectrometry monitoring of fungal cultures led to the identification of four peptaibols with a rare threonine residue. Phytochemistry. 143: 45-53. PMID 28772192 DOI: 10.1016/J.Phytochem.2017.07.004  0.778
2017 Leyte-Lugo M, Britton ER, Foil DH, Brown AR, Todd DA, Rivera-Chávez J, Oberlies NH, Cech NB. Secondary Metabolites from the Leaves of the Medicinal Plant Goldenseal (Hydrastis canadensis). Phytochemistry Letters. 20: 54-60. PMID 28736584 DOI: 10.1016/J.Phytol.2017.03.012  0.399
2017 Rivera-Chávez J, Raja HA, Graf TN, Burdette JE, Pearce CJ, Oberlies NH. Biosynthesis of Fluorinated Peptaibols Using a Site-Directed Building Block Incorporation Approach. Journal of Natural Products. PMID 28594169 DOI: 10.1021/Acs.Jnatprod.7B00189  0.333
2017 Kellogg JJ, Graf TN, Paine MF, McCune JS, Kvalheim OM, Oberlies NH, Cech NB. Comparison of Metabolomics Approaches for Evaluating the Variability of Complex Botanical Preparations: Green Tea (Camellia sinensis) as a Case Study. Journal of Natural Products. PMID 28453261 DOI: 10.1021/Acs.Jnatprod.6B01156  0.328
2017 González-Medina M, Owen JR, El-Elimat T, Pearce CJ, Oberlies NH, Figueroa M, Medina-Franco JL. Scaffold Diversity of Fungal Metabolites. Frontiers in Pharmacology. 8: 180. PMID 28420994 DOI: 10.3389/Fphar.2017.00180  0.673
2017 Wang J, Zhu X, Kolli S, Wang H, Pearce CJ, Oberlies NH, Phelps MA. Plasma pharmacokinetics and bioavailability of verticillin A following different routes of administration in mice using liquid chromatography tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis. 139: 187-192. PMID 28284083 DOI: 10.1016/J.Jpba.2017.02.051  0.3
2017 VanderMolen KM, Little JG, Sica VP, El-Elimat T, Raja HA, Oberlies NH, Baker TR, Mahony C. Safety assessment of mushrooms in dietary supplements by combining analytical data with in silico toxicology evaluation. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. PMID 28267567 DOI: 10.1016/J.Fct.2017.03.005  0.77
2017 Raja HA, Miller AN, Pearce CJ, Oberlies NH. Fungal Identification Using Molecular Tools: A Primer for the Natural Products Research Community. Journal of Natural Products. PMID 28199101 DOI: 10.1021/Acs.Jnatprod.6B01085  0.325
2017 Paguigan ND, El-Elimat T, Kao D, Raja HA, Pearce CJ, Oberlies NH. Enhanced dereplication of fungal cultures via use of mass defect filtering. The Journal of Antibiotics. PMID 28074050 DOI: 10.1038/Ja.2016.145  0.794
2017 Adibi A, Rees ER, McCarley S, Sica VP, Oberlies NH. CHARACTERIZATION AND ISOLATION OF PEPTIDE METABOLITES OF AN ANTIFUNGAL BACTERIAL ISOLATE IDENTIFIED AS BACILLUS AMYLOLIQUEFACIENS SUBSPECIES PLANTARUM STRAIN FZB42 Journal of Microbiology, Biotechnology and Food Sciences. 6: 1309-1313. DOI: 10.15414/Jmbfs.2017.6.6.1309-1313  0.778
2017 Raja HA, Paguigan ND, Fournier J, Oberlies NH. Additions to Lindgomyces (Lindgomycetaceae, Pleosporales, Dothideomycetes), including two new species occurring on submerged wood from North Carolina, USA, with notes on secondary metabolite profiles Mycological Progress. 16: 535-552. DOI: 10.1007/S11557-017-1282-4  0.754
2016 Egan JM, Kaur A, Raja HA, Kellogg JJ, Oberlies NH, Cech NB. Antimicrobial fungal endophytes from the botanical medicine goldenseal (Hydrastis canadensis). Phytochemistry Letters. 17: 219-225. PMID 28603575 DOI: 10.1016/J.Phytol.2016.07.031  0.794
2016 Kaur A, Oberhofer M, Juzumaite M, Raja HA, Gulledge TV, Kao D, Faeth SH, Laster SM, Oberlies NH, Cech NB. Secondary Metabolites from Fungal Endophytes of Echinacea purpurea Suppress Cytokine Secretion by Macrophage-Type Cells. Natural Product Communications. 11: 1143-1146. PMID 28479944 DOI: 10.1177/1934578X1601100827  0.398
2016 Brooks WC, Paguigan ND, Raja HA, Moy FJ, Cech NB, Pearce CJ, Oberlies NH. qNMR for profiling the production of fungal secondary metabolites. Magnetic Resonance in Chemistry : Mrc. PMID 28024162 DOI: 10.1002/Mrc.4571  0.769
2016 Rivera-Chávez J, Raja HA, Metri P, Xue D, Pearce CJ, Oberlies NH. Peptaibols from Tichoderma sp. (MSX70741): Isolation, structure elucidation and biological activity. Planta Medica. 81: S1-S381. PMID 27975891 DOI: 10.1055/S-0036-1596692  0.325
2016 El-Elimat T, Raja HA, Day CS, McFeeters H, McFeeters RL, Oberlies NH. α-Pyrone derivatives, tetra/hexahydroxanthones, and cyclodepsipeptides from two freshwater fungi. Bioorganic & Medicinal Chemistry. PMID 27964996 DOI: 10.1016/J.Bmc.2016.11.059  0.668
2016 Kinghorn AD, DE Blanco EJ, Lucas DM, Rakotondraibe HL, Orjala J, Soejarto DD, Oberlies NH, Pearce CJ, Wani MC, Stockwell BR, Burdette JE, Swanson SM, Fuchs JR, Phelps MA, Xu L, et al. Discovery of Anticancer Agents of Diverse Natural Origin. Anticancer Research. 36: 5623-5637. PMID 27793884 DOI: 10.21873/Anticanres.11146  0.404
2016 González-Medina M, Prieto-Martínez FD, Naveja JJ, Méndez-Lucio O, El-Elimat T, Pearce CJ, Oberlies NH, Figueroa M, Medina-Franco JL. Chemoinformatic expedition of the chemical space of fungal products. Future Medicinal Chemistry. PMID 27485744 DOI: 10.4155/Fmc-2016-0079  0.643
2016 Sica VP, Figueroa M, Raja HA, El-Elimat T, Darveaux BA, Pearce CJ, Oberlies NH. Optimizing production and evaluating biosynthesis in situ of a herbicidal compound, mevalocidin, from Coniolariella sp. Journal of Industrial Microbiology & Biotechnology. PMID 27221133 DOI: 10.1007/S10295-016-1782-2  0.802
2016 Sica VP, Rees ER, Tchegnon E, Bardsley RH, Raja HA, Oberlies NH. Spatial and Temporal Profiling of Griseofulvin Production in Xylaria cubensis Using Mass Spectrometry Mapping. Frontiers in Microbiology. 7: 544. PMID 27199902 DOI: 10.3389/Fmicb.2016.00544  0.772
2016 Graf TN, Cech NB, Polyak SJ, Oberlies NH. A validated UHPLC-tandem mass spectrometry method for quantitative analysis of flavonolignans in milk thistle (Silybum marianum) extracts. Journal of Pharmaceutical and Biomedical Analysis. 126: 26-33. PMID 27136284 DOI: 10.1016/J.Jpba.2016.04.028  0.356
2016 Kaur A, Raja HA, Swenson DC, Agarwal R, Deep G, Falkinham JO, Oberlies NH. Talarolutins A-D: Meroterpenoids from an endophytic fungal isolate of Talaromyces minioluteus. Phytochemistry. PMID 27048854 DOI: 10.1016/J.Phytochem.2016.03.013  0.36
2016 Paguigan ND, Raja HA, Day CS, Oberlies NH. Acetophenone derivatives from a freshwater fungal isolate of recently described Lindgomyces madisonensis (G416). Phytochemistry. PMID 26988728 DOI: 10.1016/J.Phytochem.2016.03.007  0.791
2016 Deep G, Kumar R, Jain AK, Dhar D, Panigrahi GK, Hussain A, Agarwal C, El-Elimat T, Sica VP, Oberlies NH, Agarwal R. Graviola inhibits hypoxia-induced NADPH oxidase activity in prostate cancer cells reducing their proliferation and clonogenicity. Scientific Reports. 6: 23135. PMID 26979487 DOI: 10.1038/Srep23135  0.772
2016 Kellogg JJ, Todd DA, Egan JM, Raja HA, Oberlies NH, Kvalheim OM, Cech NB. Biochemometrics for Natural Products Research: Comparison of Data Analysis Approaches and Application to Identification of Bioactive Compounds. Journal of Natural Products. PMID 26841051 DOI: 10.1021/Acs.Jnatprod.5B01014  0.799
2016 Sica VP, El-Elimat T, Oberlies NH. In situ analysis of Asimina triloba (paw paw) plant tissues for acetogenins via the droplet-liquid microjunction-surface sampling probe coupled to UHPLC-PDA-HRMS/MS Analytical Methods. 8: 6143-6149. DOI: 10.1039/C6Ay01583B  0.794
2016 Egan JM, Kaur A, Raja HA, Kellogg JJ, Oberlies NH, Cech NB. Antimicrobial fungal endophytes from the botanical medicine goldenseal (Hydrastis canadensis) Phytochemistry Letters. 17: 219-225. DOI: 10.1016/j.phytol.2016.07.031  0.784
2015 Wang L, Rotter S, Ladurner A, Heiss EH, Oberlies NH, Dirsch VM, Atanasov AG. Silymarin Constituents Enhance ABCA1 Expression in THP-1 Macrophages. Molecules (Basel, Switzerland). 21. PMID 26729088 DOI: 10.3390/Molecules21010055  0.304
2015 Sy-Cordero AA, Figueroa M, Raja HA, Meza Aviña ME, Croatt MP, Adcock AF, Kroll DJ, Wani MC, Pearce CJ, Oberlies NH. Spiroscytalin, a new tetramic acid and other metabolites of mixed biogenesis from Scytalidium cuboideum. Tetrahedron. 71: 8899-904. PMID 26525642 DOI: 10.1016/J.Tet.2015.09.073  0.382
2015 Fakhouri L, El-Elimat T, Hurst DP, Reggio PH, Pearce CJ, Oberlies NH, Croatt MP. Isolation, semisynthesis, covalent docking and transforming growth factor beta-activated kinase 1 (TAK1)-inhibitory activities of (5Z)-7-oxozeaenol analogues. Bioorganic & Medicinal Chemistry. PMID 26481152 DOI: 10.1016/J.Bmc.2015.09.037  0.65
2015 Kaur A, Raja HA, Deep G, Agarwal R, Oberlies NH. Pannorin B, a new naphthopyrone from an endophytic fungal isolate of Penicillium sp. Magnetic Resonance in Chemistry : Mrc. PMID 26365944 DOI: 10.1002/Mrc.4324  0.392
2015 Gufford BT, Graf TN, Paguigan ND, Oberlies NH, Paine MF. Chemoenzymatic Synthesis, Characterization, and Scale-Up of Milk Thistle Flavonolignan Glucuronides. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 1734-43. PMID 26316643 DOI: 10.1124/Dmd.115.066076  0.759
2015 Raja HA, El-Elimat T, Oberlies NH, Shearer CA, Miller AN, Tanaka K, Hashimoto A, Fournier J. Minutisphaerales (Dothideomycetes, Ascomycota): a new order of freshwater ascomycetes including a new family, Minutisphaeraceae, and two new species from North Carolina, USA. Mycologia. 107: 845-62. PMID 26315030 DOI: 10.3852/15-013  0.645
2015 Sica VP, Raja HA, El-Elimat T, Kertesz V, Van Berkel GJ, Pearce CJ, Oberlies NH. Dereplicating and Spatial Mapping of Secondary Metabolites from Fungal Cultures in Situ. Journal of Natural Products. 78: 1926-36. PMID 26192135 DOI: 10.1021/Acs.Jnatprod.5B00268  0.796
2015 Alali F, El-Elimat T, Albataineh H, Al-Balas Q, Al-Gharaibeh M, Falkinham JO, Chen WL, Swanson SM, Oberlies NH. Cytotoxic Homoisoflavones from the Bulbs of Bellevalia eigii. Journal of Natural Products. 78: 1708-15. PMID 26147490 DOI: 10.1021/Acs.Jnatprod.5B00357  0.762
2015 Gufford BT, Chen G, Vergara AG, Lazarus P, Oberlies NH, Paine MF. Milk Thistle Constituents Inhibit Raloxifene Intestinal Glucuronidation: A Potential Clinically Relevant Natural Product-Drug Interaction. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 1353-9. PMID 26070840 DOI: 10.1124/Dmd.115.065086  0.307
2015 Kaur A, Raja HA, Darveaux BA, Chen WL, Swanson SM, Pearce CJ, Oberlies NH. New diketopiperazine dimer from a filamentous fungal isolate of Aspergillus sydowii. Magnetic Resonance in Chemistry : Mrc. 53: 616-9. PMID 26040447 DOI: 10.1002/Mrc.4254  0.425
2015 Raja HA, Kaur A, El-Elimat T, Figueroa M, Kumar R, Deep G, Agarwal R, Faeth SH, Cech NB, Oberlies NH. Phylogenetic and chemical diversity of fungal endophytes isolated from Silybum marianum (L) Gaertn. (milk thistle). Mycology. 6: 8-27. PMID 26000195 DOI: 10.1080/21501203.2015.1009186  0.685
2015 Todd DA, Gulledge TV, Britton ER, Oberhofer M, Leyte-Lugo M, Moody AN, Shymanovich T, Grubbs LF, Juzumaite M, Graf TN, Oberlies NH, Faeth SH, Laster SM, Cech NB. Ethanolic Echinacea purpurea Extracts Contain a Mixture of Cytokine-Suppressive and Cytokine-Inducing Compounds, Including Some That Originate from Endophytic Bacteria. Plos One. 10: e0124276. PMID 25933416 DOI: 10.1371/Journal.Pone.0124276  0.32
2015 Daly SM, Elmore BO, Kavanaugh JS, Triplett KD, Figueroa M, Raja HA, El-Elimat T, Crosby HA, Femling JK, Cech NB, Horswill AR, Oberlies NH, Hall PR. ω-Hydroxyemodin limits staphylococcus aureus quorum sensing-mediated pathogenesis and inflammation. Antimicrobial Agents and Chemotherapy. 59: 2223-35. PMID 25645827 DOI: 10.1128/Aac.04564-14  0.618
2015 Bussey RO, Kaur A, Todd DA, Egan JM, El-Elimat T, Graf TN, Raja HA, Oberlies NH, Cech NB. Comparison of the chemistry and diversity of endophytes isolated from wild-harvested and greenhouse-cultivated yerba mansa (Anemopsis californica). Phytochemistry Letters. 11: 202-208. PMID 25642298 DOI: 10.1016/J.Phytol.2014.12.013  0.809
2015 El-Elimat T, Figueroa M, Raja HA, Graf TN, Swanson SM, Falkinham JO, Wani MC, Pearce CJ, Oberlies NH. Biosynthetically Distinct Cytotoxic Polyketides from Setophoma terrestris. European Journal of Organic Chemistry. 2015: 109-121. PMID 25574154 DOI: 10.1002/Ejoc.201402984  0.669
2015 Barr JT, Jones JP, Oberlies NH, Paine MF. Inhibition of human aldehyde oxidase activity by diet-derived constituents: structural influence, enzyme-ligand interactions, and clinical relevance. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 34-41. PMID 25326286 DOI: 10.1124/Dmd.114.061192  0.301
2015 El-Elimat T, Raja HA, Figueroa M, Swanson SM, Falkinham JO, Lucas DM, Grever MR, Wani MC, Pearce CJ, Oberlies NH. Sorbicillinoid analogs with cytotoxic and selective anti-Aspergillus activities from Scytalidium album. The Journal of Antibiotics. 68: 191-6. PMID 25248727 DOI: 10.1038/Ja.2014.125  0.655
2015 Raja H, El-Elimat T, Shearer C, Miller A, Tanaka K, Oberlies N. Chemical mycology of freshwater ascomycetes from North Carolina, USA Planta Medica. 81. DOI: 10.1055/S-0035-1556387  0.592
2015 Sica V, Raja H, El-Elimat T, Kertesz V, Van Berkel G, Pearce C, Oberlies N. Profiling fungal cultures in situ via the droplet-LMJ-SSP coupled with UPLC-PDA-HRMS-MS/MS Planta Medica. 81. DOI: 10.1055/S-0035-1556370  0.771
2015 Egan J, Kaur A, Raja H, Brown A, Oberlies N, Cech N. Prevalence of antimicrobial fungal metabolites in Hydrastis canadensis crude extracts Planta Medica. 81. DOI: 10.1055/S-0035-1556312  0.779
2015 Kao D, Raja H, Paguigan N, Cech N, Oberlies N. Triggering epipolythiodioxopiperazine alkaloid biosynthesis in fungal endophytes of Goldenseal (Hydrastis Canadensis) Planta Medica. 81. DOI: 10.1055/S-0035-1556309  0.773
2015 Paguigan N, Graf T, Gufford B, Paine M, Oberlies N. Glucuronide metabolites of flavonolignans from milk thistle (Silybum marianum): Structural characterization Planta Medica. 81. DOI: 10.1055/S-0035-1556228  0.757
2015 Graf T, Paguigan N, Gufford B, Paine M, Oberlies N. Glucuronide metabolites of flavonolignans from milk thistle (Silybum marianum): Enzymatic synthesis Planta Medica. 81. DOI: 10.1055/S-0035-1556227  0.753
2015 Britton E, Ibberson C, Leyte-Lugo M, Bussey III R, Raja H, Oberlies N, Horswill A, Cech N. A new anti-virulence strategy against pathogenic bacteria: Targeting spreading factors Planta Medica. 81. DOI: 10.1055/S-0035-1556215  0.356
2015 Kellogg J, Todd D, Egan J, Raja H, Oberlies N, Kvalheim O, Cech N. Chemometric-directed bioexploration of natural products Planta Medica. 81. DOI: 10.1055/S-0035-1556170  0.764
2014 El-Elimat T, Raja HA, Day CS, Chen WL, Swanson SM, Oberlies NH. Greensporones: resorcylic acid lactones from an aquatic Halenospora sp. Journal of Natural Products. 77: 2088-98. PMID 25093280 DOI: 10.1021/Np500497R  0.664
2014 Gufford BT, Chen G, Lazarus P, Graf TN, Oberlies NH, Paine MF. Identification of diet-derived constituents as potent inhibitors of intestinal glucuronidation. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 42: 1675-83. PMID 25008344 DOI: 10.1124/Dmd.114.059451  0.307
2014 VanderMolen KM, Darveaux BA, Chen WL, Swanson SM, Pearce CJ, Oberlies NH. Epigenetic Manipulation of a Filamentous Fungus by the Proteasome-Inhibitor Bortezomib Induces the Production of an Additional Secondary Metabolite. Rsc Advances. 4: 18329-18335. PMID 24955237 DOI: 10.1039/C4Ra00274A  0.802
2014 VanderMolen KM, Ainslie GR, Paine MF, Oberlies NH. Labeled content of two furanocoumarins in dietary supplements correlates with neither actual content nor CYP3A inhibitory activity. Journal of Pharmaceutical and Biomedical Analysis. 98: 260-5. PMID 24951959 DOI: 10.1016/J.Jpba.2014.05.038  0.783
2014 Figueroa M, Jarmusch AK, Raja HA, El-Elimat T, Kavanaugh JS, Horswill AR, Cooks RG, Cech NB, Oberlies NH. Polyhydroxyanthraquinones as quorum sensing inhibitors from the guttates of Penicillium restrictum and their analysis by desorption electrospray ionization mass spectrometry. Journal of Natural Products. 77: 1351-8. PMID 24911880 DOI: 10.1021/Np5000704  0.667
2014 El-Elimat T, Raja HA, Figueroa M, Falkinham JO, Oberlies NH. Isochromenones, isobenzofuranone, and tetrahydronaphthalenes produced by Paraphoma radicina, a fungus isolated from a freshwater habitat. Phytochemistry. 104: 114-20. PMID 24833033 DOI: 10.1016/J.Phytochem.2014.04.006  0.668
2014 Bussey RO, Sy-Cordero AA, Figueroa M, Carter FS, Falkinham JO, Oberlies NH, Cech NB. Antimycobacterial furofuran lignans from the roots of Anemopsis californica. Planta Medica. 80: 498-501. PMID 24687738 DOI: 10.1055/S-0034-1368352  0.382
2014 El-Elimat T, Raja HA, Graf TN, Faeth SH, Cech NB, Oberlies NH. Flavonolignans from Aspergillus iizukae, a fungal endophyte of milk thistle (Silybum marianum). Journal of Natural Products. 77: 193-9. PMID 24456525 DOI: 10.1021/Np400955Q  0.655
2014 Raja H, Baker T, Little J, Oberlies N. DNA barcoding for identification of species in mushrooms: A component of product certification Planta Medica. 80. DOI: 10.1055/S-0034-1382740  0.3
2014 Sica V, El-Elimat T, Raja H, Oberlies N. Exploring fungal ecology with desorption electrospray ionization mass spectrometry imaging Planta Medica. 80. DOI: 10.1055/S-0034-1382658  0.764
2014 El-Elimat T, Graf T, Baker T, Little J, Oberlies N. Profiling of mushrooms using a UHPLC/UV/ELSD/HRMS dereplication protocol: A component of the safety assessment process Planta Medica. 80. DOI: 10.1055/S-0034-1382650  0.57
2014 Kaur A, Swanson S, Pearce C, Oberlies N. Natural products from a filamentous fungal isolate of an unidentified species Planta Medica. 80. DOI: 10.1055/S-0034-1382416  0.329
2014 Paguigan N, Raja H, El-Elimat T, Oberlies N. New polyketides from a freshwater Lindgomycetaceae sp. Planta Medica. 80. DOI: 10.1055/S-0034-1382415  0.764
2014 Egan J, Kaur A, Raja H, Brown A, Oberlies N, Cech N. Antimicrobial secondary metabolites from fungal endophytes of goldenseal (Hydrastis canadensis) Planta Medica. 80. DOI: 10.1055/S-0034-1382413  0.793
2014 Kao D, Kaur A, Raja H, El-Elimat T, Oberhofer M, Juzumaite M, Gulledge T, Laster S, Cech N, Faeth S, Oberlies N. Chemical investigation of fungal endophytes from Echinacea purpurea Planta Medica. 80. DOI: 10.1055/S-0034-1382406  0.614
2014 Sica VP, Raja HA, El-Elimat T, Oberlies NH. Mass spectrometry imaging of secondary metabolites directly on fungal cultures Rsc Advances. 4: 63221-63227. DOI: 10.1039/C4Ra11564C  0.799
2014 Alali FQ, Amrine CSM, El-Elimat T, Alkofahi A, Tawaha K, Gharaibah M, Swanson SM, Falkinham JO, Cabeza M, Sánchez A, Figueroa M, Oberlies NH. Bioactive withanolides from Withania obtusifolia Phytochemistry Letters. 9: 96-101. DOI: 10.1016/J.Phytol.2014.05.002  0.761
2013 Vandermolen KM, Raja HA, El-Elimat T, Oberlies NH. Evaluation of culture media for the production of secondary metabolites in a natural products screening program. Amb Express. 3: 71. PMID 24342059 DOI: 10.1186/2191-0855-3-71  0.796
2013 El-Elimat T, Figueroa M, Raja HA, Adcock AF, Kroll DJ, Swanson SM, Wani MC, Pearce CJ, Oberlies NH. Waol A, trans-dihydrowaol A, and cis-dihydrowaol A: polyketide-derived γ-lactones from a Volutella species. Tetrahedron Letters. 54: 4300-4302. PMID 23956472 DOI: 10.1016/J.Tetlet.2013.06.008  0.651
2013 El-Elimat T, Figueroa M, Ehrmann BM, Cech NB, Pearce CJ, Oberlies NH. High-resolution MS, MS/MS, and UV database of fungal secondary metabolites as a dereplication protocol for bioactive natural products. Journal of Natural Products. 76: 1709-16. PMID 23947912 DOI: 10.1021/Np4004307  0.665
2013 Won CS, Lan T, Vandermolen KM, Dawson PA, Oberlies NH, Widmer WW, Scarlett YV, Paine MF. A modified grapefruit juice eliminates two compound classes as major mediators of the grapefruit juice-fexofenadine interaction: an in vitro-in vivo "connect". Journal of Clinical Pharmacology. 53: 982-90. PMID 23878024 DOI: 10.1002/Jcph.136  0.78
2013 Althagafy HS, Meza-Aviña ME, Oberlies NH, Croatt MP. Mechanistic study of the biomimetic synthesis of flavonolignan diastereoisomers in milk thistle. The Journal of Organic Chemistry. 78: 7594-600. PMID 23876147 DOI: 10.1021/Jo4011377  0.728
2013 Figueroa M, Raja H, Falkinham JO, Adcock AF, Kroll DJ, Wani MC, Pearce CJ, Oberlies NH. Peptaibols, tetramic acid derivatives, isocoumarins, and sesquiterpenes from a Bionectria sp. (MSX 47401). Journal of Natural Products. 76: 1007-15. PMID 23806109 DOI: 10.1021/Np3008842  0.427
2013 Brantley SJ, Graf TN, Oberlies NH, Paine MF. A systematic approach to evaluate herb-drug interaction mechanisms: investigation of milk thistle extracts and eight isolated constituents as CYP3A inhibitors. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 1662-70. PMID 23801821 DOI: 10.1124/Dmd.113.052563  0.354
2013 Vandermolen KM, Cech NB, Paine MF, Oberlies NH. Rapid Quantitation of Furanocoumarins and Flavonoids in Grapefruit Juice using Ultra-Performance Liquid Chromatography. Phytochemical Analysis : Pca. 24: 654-60. PMID 23780830 DOI: 10.1002/Pca.2449  0.785
2013 Althagafy HS, Graf TN, Sy-Cordero AA, Gufford BT, Paine MF, Wagoner J, Polyak SJ, Croatt MP, Oberlies NH. Semisynthesis, cytotoxicity, antiviral activity, and drug interaction liability of 7-O-methylated analogues of flavonolignans from milk thistle. Bioorganic & Medicinal Chemistry. 21: 3919-26. PMID 23673225 DOI: 10.1016/J.Bmc.2013.04.017  0.773
2013 Bame JR, Graf TN, Junio HA, Bussey RO, Jarmusch SA, El-Elimat T, Falkinham JO, Oberlies NH, Cech RA, Cech NB. Sarothrin from Alkanna orientalis is an antimicrobial agent and efflux pump inhibitor. Planta Medica. 79: 327-9. PMID 23468310 DOI: 10.1055/S-0032-1328259  0.633
2013 Napolitano JG, Lankin DC, Graf TN, Friesen JB, Chen SN, McAlpine JB, Oberlies NH, Pauli GF. HiFSA fingerprinting applied to isomers with near-identical NMR spectra: the silybin/isosilybin case. The Journal of Organic Chemistry. 78: 2827-39. PMID 23461697 DOI: 10.1021/Jo302720H  0.304
2013 El-Elimat T, Figueroa M, Raja HA, Graf TN, Adcock AF, Kroll DJ, Day CS, Wani MC, Pearce CJ, Oberlies NH. Benzoquinones and terphenyl compounds as phosphodiesterase-4B inhibitors from a fungus of the order Chaetothyriales (MSX 47445). Journal of Natural Products. 76: 382-7. PMID 23301853 DOI: 10.1021/Np300749W  0.664
2013 Sy-Cordero AA, Graf TN, Runyon SP, Wani MC, Kroll DJ, Agarwal R, Brantley SJ, Paine MF, Polyak SJ, Oberlies NH. Enhanced bioactivity of silybin B methylation products. Bioorganic & Medicinal Chemistry. 21: 742-7. PMID 23260576 DOI: 10.1016/J.Bmc.2012.11.035  0.403
2013 Bussey III R, El-Elimat T, Kaur A, Raja H, Oberlies N, Cech N. Antimicrobial Endophytes from the Antimicrobial Botanical Yerba mansa (Anemposis californica) Planta Medica. 79. DOI: 10.1055/S-0033-1348701  0.606
2013 Figueroa M, El-Elimat T, Raja H, Falkinham III J, Swanson S, Pearce C, Oberlies N. Novel Xanthone Dimers and Azaphilones from Phomopsis sp. (MSX 54505): Isolation, Structure Elucidation, and Biological Activity Planta Medica. 79. DOI: 10.1055/S-0033-1348670  0.629
2013 Raja H, Kaur A, Figueroa M, El-Elimat T, Cech N, Faeth S, Oberlies N. Mycology and Chemical Investigations of Fungal Endophytes from Medicinal Herbs (Milk Thistle and Goldenseal) Planta Medica. 79. DOI: 10.1055/S-0033-1348664  0.624
2013 Pearce C, Veasey L, Tillotson M, Darveaux B, Lawrence M, Sica V, Oberlies N. Mevalocidin: A Fungus Metabolite with Herbicide Activity and Potential for use in Organic Farming Planta Medica. 79. DOI: 10.1055/S-0033-1348662  0.749
2013 VanderMolen K, Raja H, Oberlies N. Effects of Media on the Fungal Metabolome Planta Medica. 79. DOI: 10.1055/S-0033-1348656  0.769
2013 El-Elimat T, Figueroa M, Adcock A, Kroll D, Swanson S, Wani M, Pearce C, Oberlies N. Cytotoxic Polyketides from an Unidentified Fungus (MSX 45109) Planta Medica. 79. DOI: 10.1055/S-0033-1348654  0.65
2013 El-Elimat T, Raja H, Oberlies N. Cyclodepsipeptides, α-Pyrone Derivatives and Secalonic Acids from Two Unidentified Freshwater Fungi (G100 and G102) Planta Medica. 79. DOI: 10.1055/S-0033-1348653  0.561
2013 Paguigan N, ELimat TE, Pearce C, Oberlies N. A High Resolution MS, MS/MS Database Using LTQ-Orbitrap XL Mass Spectrometer Interfaced with H-ESI for Dereplication of Fungal Secondary Metabolites Planta Medica. 79. DOI: 10.1055/S-0033-1348642  0.746
2013 Raja HA, Oberlies NH, El-Elimat T, Miller AN, Zelski SE, Shearer CA. Lindgomyces angustiascus, (Lindgomycetaceae, Pleosporales, Dothideomycetes), a new lignicolous species from freshwater habitats in the USA Mycoscience. 54: 353-361. DOI: 10.1016/J.Myc.2012.12.004  0.605
2013 El-Elimat T, Figueroa M, Raja HA, Adcock AF, Kroll DJ, Swanson SM, Wani MC, Pearce CJ, Oberlies NH. ChemInform Abstract: Waol A (I), trans-Dihydrowaol A (II), and cis-Dihydrowaol A (III): Polyketide-Derived γ-Lactones from a Volutella Species. Cheminform. 44: no-no. DOI: 10.1002/chin.201346133  0.518
2012 El-Elimat T, Zhang X, Jarjoura D, Moy FJ, Orjala J, Kinghorn AD, Pearce CJ, Oberlies NH. Chemical Diversity of Metabolites from Fungi, Cyanobacteria, and Plants Relative to FDA-Approved Anticancer Agents. Acs Medicinal Chemistry Letters. 3: 645-649. PMID 22993669 DOI: 10.1021/Ml300105S  0.622
2012 Sy-Cordero AA, Pearce CJ, Oberlies NH. Revisiting the enniatins: a review of their isolation, biosynthesis, structure determination and biological activities. The Journal of Antibiotics. 65: 541-9. PMID 22990381 DOI: 10.1038/Ja.2012.71  0.392
2012 Figueroa M, Graf TN, Ayers S, Adcock AF, Kroll DJ, Yang J, Swanson SM, Munoz-Acuna U, Carcache de Blanco EJ, Agrawal R, Wani MC, Darveaux BA, Pearce CJ, Oberlies NH. Cytotoxic epipolythiodioxopiperazine alkaloids from filamentous fungi of the Bionectriaceae. The Journal of Antibiotics. 65: 559-64. PMID 22968289 DOI: 10.1038/Ja.2012.69  0.399
2012 Ayers S, Ehrmann BM, Adcock AF, Kroll DJ, Carcache de Blanco EJ, Shen Q, Swanson SM, Falkinham JO, Wani MC, Mitchell SM, Pearce CJ, Oberlies NH. Peptaibols from two unidentified fungi of the order Hypocreales with cytotoxic, antibiotic, and anthelmintic activities. Journal of Peptide Science : An Official Publication of the European Peptide Society. 18: 500-10. PMID 22744757 DOI: 10.1002/Psc.2425  0.4
2012 Ayers S, Graf TN, Adcock AF, Kroll DJ, Shen Q, Swanson SM, Matthew S, Carcache de Blanco EJ, Wani MC, Darveaux BA, Pearce CJ, Oberlies NH. Cytotoxic xanthone-anthraquinone heterodimers from an unidentified fungus of the order Hypocreales (MSX 17022). The Journal of Antibiotics. 65: 3-8. PMID 22068158 DOI: 10.1038/Ja.2011.95  0.401
2012 El-Elimat T, Ehrmann B, Cech N, Pearce C, Oberlies N. De-inventing the wheel: Dereplication tools for natural products research Planta Medica. 78. DOI: 10.1055/S-0032-1321228  0.588
2012 El-Elimat T, Figueroa M, Graf T, Adcock A, Kroll D, Wani M, Pearce C, Oberlies N. Two benzoquinones and one terphenyl compound from an unidentified fungus (MSX 47445) Planta Medica. 78. DOI: 10.1055/S-0032-1320773  0.635
2012 Figueroa M, Falkinham III J, Adcock A, Kroll D, Raja H, Wani M, Pearce C, Oberlies N. Bioactive constituents from Bionectria sp. (MSX 47401): isolation, structure elucidation and biological activities Planta Medica. 78. DOI: 10.1055/S-0032-1320772  0.341
2012 VanderMolen K, Darveaux B, Pearce C, Oberlies N. Chemical epigenetics induce additional secondary metabolites in a filamentous fungus Planta Medica. 78. DOI: 10.1055/S-0032-1320752  0.784
2012 Sy-Cordero AA, Graf TN, Adcock AF, Kroll DJ, Shen Q, Swanson SM, Wani MC, Pearce CJ, Oberlies NH. Correction to Cyclodepsipeptides, Sesquiterpenoids, and Other Cytotoxic Metabolites from the Filamentous Fungus Trichothecium sp. (MSX 51320) Journal of Natural Products. 75: 307-307. DOI: 10.1021/Np3000766  0.301
2011 Ayers S, Ehrmann BM, Adcock AF, Kroll DJ, Wani MC, Pearce CJ, Oberlies NH. Thielavin B methyl ester: a cytotoxic benzoate trimer from an unidentified fungus (MSX 55526) from the Order Sordariales. Tetrahedron Letters. 52: 5733-5735. PMID 22566715 DOI: 10.1016/J.Tetlet.2011.08.125  0.346
2011 Ayers S, Graf TN, Adcock AF, Kroll DJ, Shen Q, Swanson SM, Wani MC, Darveaux BA, Pearce CJ, Oberlies NH. Obionin B: An o-pyranonaphthoquinone decaketide from an unidentified fungus (MSX 63619) from the Order Pleosporales. Tetrahedron Letters. 52: 5128-5230. PMID 22025810 DOI: 10.1016/J.Tetlet.2011.07.102  0.323
2011 Sy-Cordero AA, Graf TN, Adcock AF, Kroll DJ, Shen Q, Swanson SM, Wani MC, Pearce CJ, Oberlies NH. Cyclodepsipeptides, sesquiterpenoids, and other cytotoxic metabolites from the filamentous fungus Trichothecium sp. (MSX 51320). Journal of Natural Products. 74: 2137-42. PMID 21978324 DOI: 10.1021/Np2004243  0.413
2011 Junio HA, Sy-Cordero AA, Ettefagh KA, Burns JT, Micko KT, Graf TN, Richter SJ, Cannon RE, Oberlies NH, Cech NB. Synergy-directed fractionation of botanical medicines: a case study with goldenseal (Hydrastis canadensis). Journal of Natural Products. 74: 1621-9. PMID 21661731 DOI: 10.1021/Np200336G  0.382
2011 VanderMolen KM, McCulloch W, Pearce CJ, Oberlies NH. Romidepsin (Istodax, NSC 630176, FR901228, FK228, depsipeptide): a natural product recently approved for cutaneous T-cell lymphoma. The Journal of Antibiotics. 64: 525-31. PMID 21587264 DOI: 10.1038/Ja.2011.35  0.793
2011 Ayers S, Graf TN, Adcock AF, Kroll DJ, Matthew S, Carcache de Blanco EJ, Shen Q, Swanson SM, Wani MC, Pearce CJ, Oberlies NH. Resorcylic acid lactones with cytotoxic and NF-κB inhibitory activities and their structure-activity relationships. Journal of Natural Products. 74: 1126-31. PMID 21513293 DOI: 10.1021/Np200062X  0.414
2011 Strader CR, Pearce CJ, Oberlies NH. Fingolimod (FTY720): a recently approved multiple sclerosis drug based on a fungal secondary metabolite. Journal of Natural Products. 74: 900-7. PMID 21456524 DOI: 10.1021/Np2000528  0.385
2011 Kim E, Sy-Cordero A, Graf TN, Brantley SJ, Paine MF, Oberlies NH. Isolation and identification of intestinal CYP3A inhibitors from cranberry (Vaccinium macrocarpon) using human intestinal microsomes. Planta Medica. 77: 265-70. PMID 20717876 DOI: 10.1055/S-0030-1250259  0.312
2010 Sy-Cordero AA, Graf TN, Wani MC, Kroll DJ, Pearce CJ, Oberlies NH. Dereplication of macrocyclic trichothecenes from extracts of filamentous fungi through UV and NMR profiles. The Journal of Antibiotics. 63: 539-44. PMID 20648023 DOI: 10.1038/Ja.2010.77  0.4
2010 Polyak SJ, Morishima C, Lohmann V, Pal S, Lee DY, Liu Y, Graf TN, Oberlies NH. Identification of hepatoprotective flavonolignans from silymarin. Proceedings of the National Academy of Sciences of the United States of America. 107: 5995-9. PMID 20231449 DOI: 10.1073/Pnas.0914009107  0.339
2010 Alali FQ, Gharaibeh AA, Ghawanmeh A, Tawaha K, Qandil A, Burgess JP, Sy A, Nakanishi Y, Kroll DJ, Oberlies NH. Colchicinoids from Colchicum crocifolium Boiss. (Colchicaceae). Natural Product Research. 24: 152-9. PMID 20077308 DOI: 10.1080/14786410902941097  0.635
2010 Sy-Cordero A, Graf TN, Nakanishi Y, Wani MC, Agarwal R, Kroll DJ, Oberlies NH. Large-scale isolation of flavonolignans from Silybum marianum extract affords new minor constituents and preliminary structure-activity relationships. Planta Medica. 76: 644-7. PMID 19941262 DOI: 10.1055/S-0029-1240624  0.377
2009 Oberlies NH, Rineer JI, Alali FQ, Tawaha K, Falkinham JO, Wheaton WD. Mapping of Sample Collection Data: GIS Tools for the Natural Product Researcher. Phytochemistry Letters. 2: 1-9. PMID 20161345 DOI: 10.1016/J.Phytol.2008.10.006  0.618
2009 Kinghorn AD, Carcache de Blanco EJ, Chai HB, Orjala J, Farnsworth NR, Soejarto DD, Oberlies NH, Wani MC, Kroll DJ, Pearce CJ, Swanson SM, Kramer RA, Rose WC, Fairchild CR, Vite GD, et al. Discovery of anticancer agents of diverse natural origin. Pure and Applied Chemistry. Chimie Pure Et Appliquee. 81: 1051-1063. PMID 20046887 DOI: 10.1351/Pac-Con-08-10-16  0.356
2009 Li C, Lee D, Graf TN, Phifer SS, Nakanishi Y, Riswan S, Setyowati FM, Saribi AM, Soejarto DD, Farnsworth NR, Falkinham JO, Kroll DJ, Kinghorn AD, Wani MC, Oberlies NH. Bioactive constituents of the stem bark of Mitrephora glabra. Journal of Natural Products. 72: 1949-53. PMID 19874044 DOI: 10.1021/Np900572G  0.373
2009 Falkinham JO, Wall TE, Tanner JR, Tawaha K, Alali FQ, Li C, Oberlies NH. Proliferation of antibiotic-producing bacteria and concomitant antibiotic production as the basis for the antibiotic activity of Jordan's red soils. Applied and Environmental Microbiology. 75: 2735-41. PMID 19286796 DOI: 10.1128/Aem.00104-09  0.613
2009 Ngo N, Yan Z, Graf TN, Carrizosa DR, Kashuba AD, Dees EC, Oberlies NH, Paine MF. Identification of a cranberry juice product that inhibits enteric CYP3A-mediated first-pass metabolism in humans. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 514-22. PMID 19114462 DOI: 10.1124/Dmd.108.024968  0.336
2008 Alali FQ, Tahboub YR, Ibrahim ES, Qandil AM, Tawaha K, Burgess JP, Sy A, Nakanishi Y, Kroll DJ, Oberlies NH. Pyrrolizidine alkaloids from Echium glomeratum (Boraginaceae). Phytochemistry. 69: 2341-6. PMID 18691727 DOI: 10.1016/J.Phytochem.2008.06.017  0.612
2008 Alali FQ, Gharaibeh A, Ghawanmeh A, Tawaha K, Oberlies NH. Colchicinoids from Colchicum crocifolium Boiss.: a case study in dereplication strategies for (-)-colchicine and related analogues using LC-MS and LC-PDA techniques. Phytochemical Analysis : Pca. 19: 385-94. PMID 18444231 DOI: 10.1055/S-0028-1084634  0.647
2008 Deep G, Oberlies NH, Kroll DJ, Agarwal R. Identifying the differential effects of silymarin constituents on cell growth and cell cycle regulatory molecules in human prostate cancer cells. International Journal of Cancer. 123: 41-50. PMID 18435416 DOI: 10.1002/Ijc.23485  0.309
2008 Oberlies NH, Li C, McGivney RJ, Alali FQ, Tanner JR, Falkinham JO. Microbial-mediated release of bisphenol A from polycarbonate vessels. Letters in Applied Microbiology. 46: 271-5. PMID 18069976 DOI: 10.1111/J.1472-765X.2007.02301.X  0.618
2008 Ngo N, Yan Z, Graf T, Carrizosa D, Dees E, Oberlies N, Paine M. Identification of a Cranberry Juice Product Capable of Inhibiting Enteric CYP3A-Mediated First-Pass Metabolism in Humans Planta Medica. 74. DOI: 10.1055/S-2008-1075176  0.304
2008 Cech N, Junio H, Tarney K, Cannon R, Graf T, Oberlies N. A role for non-alkaloidal constitutes in the antibacterial activity of Hydrastis canadensis Planta Medica. 74. DOI: 10.1055/S-0028-1083909  0.372
2007 Graf TN, Wani MC, Agarwal R, Kroll DJ, Oberlies NH. Gram-scale purification of flavonolignan diastereoisomers from Silybum marianum (Milk Thistle) extract in support of preclinical in vivo studies for prostate cancer chemoprevention. Planta Medica. 73: 1495-501. PMID 17948171 DOI: 10.1055/S-2007-990239  0.361
2007 Alali FQ, Tawaha K, El-Elimat T, Syouf M, El-Fayad M, Abulaila K, Nielsen SJ, Wheaton WD, Falkinham JO, Oberlies NH. Antioxidant activity and total phenolic content of aqueous and methanolic extracts of Jordanian plants: an ICBG project. Natural Product Research. 21: 1121-31. PMID 17852749 DOI: 10.1080/14786410701590285  0.739
2007 Phifer SS, Lee D, Seo EK, Kim NC, Graf TN, Kroll DJ, Navarro HA, Izydore RA, Jiménez F, Garcia R, Rose WC, Fairchild CR, Wild R, Soejarto DD, Farnsworth NR, ... ... Oberlies NH, et al. Alvaradoins E-N, antitumor and cytotoxic anthracenone C-glycosides from the leaves of Alvaradoa haitiensis. Journal of Natural Products. 70: 954-61. PMID 17552563 DOI: 10.1021/Np070005A  0.365
2007 Kroll DJ, Shaw HS, Oberlies NH. Milk thistle nomenclature: why it matters in cancer research and pharmacokinetic studies. Integrative Cancer Therapies. 6: 110-9. PMID 17548790 DOI: 10.1177/1534735407301825  0.383
2007 Deep G, Oberlies NH, Kroll DJ, Agarwal R. Isosilybin B and isosilybin A inhibit growth, induce G1 arrest and cause apoptosis in human prostate cancer LNCaP and 22Rv1 cells. Carcinogenesis. 28: 1533-42. PMID 17389612 DOI: 10.1093/Carcin/Bgm069  0.303
2006 Alali FQ, Tawaha K, El-Elimat T, Qasaymeh R, Li C, Burgess J, Nakanishi Y, Kroll DJ, Wani MC, Oberlies NH. Phytochemical studies and cytotoxicity evaluations of Colchicum tunicatum Feinbr and Colchicum hierosolymitanum Feinbr (Colchicaceae): two native Jordanian meadow saffrons. Natural Product Research. 20: 558-66. PMID 16835088 DOI: 10.1080/14786410500183381  0.76
2006 Alali FQ, Ma'aya'h AS, Alkofahi A, Qandil A, Li C, Burgess J, Wani MC, Oberlies NH. A new colchicinoid from Colchicum tauri, an unexplored meadow saffron native to Jordan Natural Product Communications. 1: 95-99. DOI: 10.1177/1934578X0600100203  0.681
2005 Li C, Lee D, Graf TN, Phifer SS, Nakanishi Y, Burgess JP, Riswan S, Setyowati FM, Saribi AM, Soejarto DD, Farnsworth NR, Falkinham JO, Kroll DJ, Kinghorn AD, Wani MC, ... Oberlies NH, et al. A hexacyclic ent-trachylobane diterpenoid possessing an oxetane ring from Mitrephora glabra. Organic Letters. 7: 5709-12. PMID 16321028 DOI: 10.1021/Ol052498L  0.365
2005 Li C, Oberlies NH. The most widely recognized mushroom: chemistry of the genus Amanita. Life Sciences. 78: 532-8. PMID 16203016 DOI: 10.1016/J.Lfs.2005.09.003  0.33
2005 Lee D, Li C, Graf TN, Vigo JS, Graham JG, Cabieses F, Farnsworth NR, Cordell GA, Kinghorn AD, Kroll DJ, Wani MC, Oberlies NH. Diterpene glycosides from Egletes viscosa. Planta Medica. 71: 792-4. PMID 16142652 DOI: 10.1055/S-2005-871227  0.311
2005 Davis-Searles PR, Nakanishi Y, Kim NC, Graf TN, Oberlies NH, Wani MC, Wall ME, Agarwal R, Kroll DJ. Milk thistle and prostate cancer: Differential effects of pure flavonolignans from Silybum marianum on antiproliferative end points in human prostate carcinoma cells Cancer Research. 65: 4448-4457. PMID 15899838 DOI: 10.1158/0008-5472.Can-04-4662  0.331
2005 Alali FQ, El-Elimat T, Li C, Qandil A, Alkofahi A, Tawaha K, Burgess JP, Nakanishi Y, Kroll DJ, Navarro HA, Falkinham JO, Wani MC, Oberlies NH. New colchicinoids from a native Jordanian meadow saffron, colchicum brachyphyllum: isolation of the first naturally occurring dextrorotatory colchicinoid. Journal of Natural Products. 68: 173-8. PMID 15730238 DOI: 10.1021/Np0496587  0.773
2004 Gu JQ, Graf TN, Lee D, Chai HB, Mi Q, Kardono LB, Setyowati FM, Ismail R, Riswan S, Farnsworth NR, Cordell GA, Pezzuto JM, Swanson SM, Kroll DJ, Falkinham JO, ... ... Oberlies NH, et al. Cytotoxic and antimicrobial constituents of the bark of Diospyros maritima collected in two geographical locations in Indonesia. Journal of Natural Products. 67: 1156-61. PMID 15270571 DOI: 10.1021/Np040027M  0.393
2003 Cain CC, Lee D, Waldo RH, Henry AT, Casida EJ, Wani MC, Wall ME, Oberlies NH, Falkinham JO. Synergistic antimicrobial activity of metabolites produced by a nonobligate bacterial predator. Antimicrobial Agents and Chemotherapy. 47: 2113-7. PMID 12821455 DOI: 10.1128/Aac.47.7.2113-2117.2003  0.397
2002 Oberlies NH, Burgess JP, Navarro HA, Pinos RE, Fairchild CR, Peterson RW, Soejarto DD, Farnsworth NR, Kinghorn AD, Wani MC, Wall ME. Novel bioactive clerodane diterpenoids from the leaves and twigs of Casearia sylvestris. Journal of Natural Products. 65: 95-9. PMID 11858737 DOI: 10.1021/Np010459M  0.387
2001 Kim NC, Oberlies NH, Brine DR, Handy RW, Wani MC, Wall ME. Isolation of symlandine from the roots of common comfrey (Symphytum officinale) using countercurrent chromatography Journal of Natural Products. 64: 251-253. PMID 11430014 DOI: 10.1021/Np0004653  0.341
2001 Oberlies NH, Burgess JP, Navarro HA, Pinos RE, Soejarto DD, Farnsworth NR, Kinghorn AD, Wani MC, Wall ME. Bioactive constituents of the roots of Licania intrapetiolaris. Journal of Natural Products. 64: 497-501. PMID 11325234 DOI: 10.1021/Np0005006  0.416
1998 Oberlies NH, Rogers LL, Martin JM, McLaughlin JL. Cytotoxic and insecticidal constituents of the unripe fruit of Persea americana. Journal of Natural Products. 61: 781-5. PMID 9644064 DOI: 10.1021/Np9800304  0.612
1997 Oberlies NH, Chang CJ, McLaughlin JL. Structure-activity relationships of diverse annonaceous acetogenins against multidrug resistant human mammary adenocarcinoma (MCF-7/Adr) cells Journal of Medicinal Chemistry. 40: 2102-2106. PMID 9207950 DOI: 10.1021/Jm9700169  0.58
1997 Oberlies NH, Croy VL, Harrison ML, McLaughlin JL. The Annonaceous acetogenin bullatacin is cytotoxic against multidrug-resistant human mammary adenocarcinoma cells Cancer Letters. 115: 73-79. PMID 9097981 DOI: 10.1016/S0304-3835(97)04716-2  0.548
1997 He K, Zeng L, Ye Q, Shi G, Oberlies NH, Zhao GX, Njoku J, McLaughlin JL. Comparative SAR evaluations of annonaceous acetogenins for pesticidal activity Pesticide Science. 49: 372-378. DOI: 10.1002/(Sici)1096-9063(199704)49:4<372::Aid-Ps543>3.0.Co;2-K  0.366
1996 Zeng L, Wu FE, Oberlies NH, McLaughlin JL, Sastrodihadjo S. Five new monotetrahydrofuran ring acetogenins from the leaves of Annona muricata Journal of Natural Products. 59: 1035-1042. PMID 8946744 DOI: 10.1021/Np960447E  0.582
1996 Zeng L, Ye Q, Oberlies NH, Shi G, Gu ZM, He K, McLaughlin JL. Recent advances in annonaceous acetogenins Natural Product Reports. 13: 275-306. PMID 8760865 DOI: 10.1039/Np9961300275  0.586
1996 Ye Q, He K, Oberlies NH, Zeng L, Shi G, Evert D, McLaughlin JL. Longimicins A-D: Novel bioactive acetogenins from Asimina longifolia (annonaceae) and structure-activity relationships of asimicin type of annonaceous acetogenins Journal of Medicinal Chemistry. 39: 1790-1796. PMID 8627602 DOI: 10.1021/Jm9600510  0.596
1995 Oberlies NH, Jones JL, Corbett TH, Fotopoulos SS, McLaughlin JL. Tumor cell growth inhibition by several Annonaceous acetogenins in an in vitro disk diffusion assay Cancer Letters. 96: 55-62. PMID 7553608 DOI: 10.1016/0304-3835(95)92759-7  0.581
1994 James Morré D, de Cabo R, Farley C, Oberlies NH, McLaughlin JL. Mode of action of bullatacin, a potent antitumor acetogenin: Inhibition of NADH oxidase activity of HELA and HL-60, but not liver, plasma membranes Life Sciences. 56: 343-348. PMID 7837933 DOI: 10.1016/0024-3205(94)00957-0  0.572
1993 Novak M, Helmick JS, Oberlies N, Rangappa KS, Clark WM, Swenton JS. The electrochemical preparation and kinetic and product studies of acylated quinol and quinol ether imines. In search of the hydrolysis products of the ultimate carcinogen of N-acetyl-2-aminofluorene The Journal of Organic Chemistry. 58: 867-878. DOI: 10.1021/Jo00056A019  0.3
Show low-probability matches.