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Justin Hanes - Publications

Affiliations: 
Chemical and Biomolecular Engineering Johns Hopkins University, Baltimore, MD 
Area:
Nanotechnology, Biomedical Engineering, Chemical Engineering, Pharmacy
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187 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Lin VY, Kaza N, Birket SE, Kim H, Edwards LJ, LaFontaine J, Liu L, Mazur M, Byzek SA, Hanes J, Tearney GJ, Raju SV, Rowe SM. Excess mucus viscosity and airway dehydration impact COPD airway clearance. The European Respiratory Journal. PMID 31672759 DOI: 10.1183/13993003.00419-2019  0.56
2019 Mead BP, Curley CT, Kim N, Negron K, Garrison WJ, Song J, Rao D, Miller GW, Mandell JW, Purow BW, Suk JS, Hanes J, Price RJ. Focused Ultrasound Preconditioning for Augmented Nanoparticle Penetration and Efficacy in the Central Nervous System. Small (Weinheim An Der Bergstrasse, Germany). e1903460. PMID 31642183 DOI: 10.1002/smll.201903460  0.88
2019 Udupa S, Nguyen S, Hoang G, Nguyen T, Quinones A, Pham K, Asaka R, Nguyen K, Elgogary A, Jung JG, Xu Q, Fu J, Thomas AG, Tsukamoto T, Hanes J, et al. Upregulation of the Glutaminase II Pathway Contributes to Glutamate Production upon Glutaminase 1 Inhibition in Pancreatic Cancer. Proteomics. e1800451. PMID 31231915 DOI: 10.1002/pmic.201800451  0.84
2019 Chisholm JF, Shenoy SK, Shade JK, Kim V, Putcha N, Carson KA, Wise R, Hansel NN, Hanes JS, Suk JS, Neptune E. Nanoparticle diffusion in spontaneously expectorated sputum as a biophysical tool to probe disease severity in COPD. The European Respiratory Journal. PMID 31164433 DOI: 10.1183/13993003.00088-2019  0.88
2019 Fernandez-Petty CM, Hughes GW, Bowers HL, Watson JD, Rosen BH, Townsend SM, Santos C, Ridley CE, Chu KK, Li Y, Leung HM, Garcia BA, Evans TIA, Libby EF, Hathorne H, ... Hanes J, et al. A glycopolymer improves vascoelasticity and mucociliary transport of abnormal cystic fibrosis mucus. Jci Insight. 4. PMID 30996141 DOI: 10.1172/jci.insight.125954  0.56
2019 Negron K, Khalasawi N, Lu B, Ho CY, Lee J, Shenoy S, Mao HQ, Wang TH, Hanes J, Suk JS. Widespread gene transfer to malignant gliomas with In vitro-to-In vivo correlation. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30978431 DOI: 10.1016/j.jconrel.2019.04.010  0.88
2019 Miller SJ, Philips T, Kim N, Dastgheyb R, Chen Z, Hsieh YC, Daigle JG, Datta M, Chew J, Vidensky S, Pham JT, Hughes EG, Robinson MB, Sattler R, Tomer R, ... ... Hanes J, et al. Molecularly defined cortical astroglia subpopulation modulates neurons via secretion of Norrin. Nature Neuroscience. PMID 30936556 DOI: 10.1038/s41593-019-0366-7  0.88
2019 Price RJ, Fisher DG, Suk JS, Hanes J, Ko HS, Kordower JH. Parkinson's disease gene therapy: Will focused ultrasound and nanovectors be the next frontier? Movement Disorders : Official Journal of the Movement Disorder Society. PMID 30908781 DOI: 10.1002/mds.27675  0.88
2019 Park JS, Oh Y, Park YJ, Park O, Yang H, Slania S, Hummers LK, Shah AA, An HT, Jang J, Horton MR, Shin J, Dietz HC, Song E, Na DH, ... ... Hanes J, et al. Targeting of dermal myofibroblasts through death receptor 5 arrests fibrosis in mouse models of scleroderma. Nature Communications. 10: 1128. PMID 30850660 DOI: 10.1038/s41467-019-09101-4  0.44
2019 Wang B, Tang Y, Oh Y, Lamb NW, Xia S, Ding Z, Chen B, Suárez MJ, Meng T, Kulkarni V, Eberhart CG, Ensign LM, Stark WJ, Hanes J, Xu Q. Controlled release of dexamethasone sodium phosphate with biodegradable nanoparticles for preventing experimental corneal neovascularization. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 30677499 DOI: 10.1016/j.nano.2019.01.001  0.76
2019 Luo L, Yang J, Oh Y, Hartsock MJ, Xia S, Kim YC, Ding Z, Meng T, Eberhart CG, Ensign L, Thorne JE, Stark WJ, Duh EJ, Xu Q, Hanes J. Controlled release of corticosteroid with biodegradable nanoparticles for treating experimental autoimmune uveitis. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30660629 DOI: 10.1016/j.jconrel.2019.01.018  0.76
2018 Hoang T, Zierden H, Date A, Ortiz J, Gumber S, Anders N, He P, Segars J, Hanes J, Mahendroo M, Ensign LM. Development of a mucoinert progesterone nanosuspension for safer and more effective prevention of preterm birth. Journal of Controlled Release : Official Journal of the Controlled Release Society. 295: 74-86. PMID 30597245 DOI: 10.1016/j.jconrel.2018.12.046  0.76
2018 Huang X, Zhuang J, Chung SW, Huang B, Halpert G, Negron K, Sun X, Yang J, Oh Y, Hwang PM, Hanes J, Suk JS. Hypoxia-Tropic Protein Nanocages for Modulation of Tumor- and Chemotherapy-Associated Hypoxia. Acs Nano. PMID 30576113 DOI: 10.1021/acsnano.8b05399  0.88
2018 Date AA, Halpert G, Babu T, Ortiz J, Kanvinde P, Dimitrion P, Narayan J, Zierden H, Betageri K, Musmanno O, Wiegand H, Huang X, Gumber S, Hanes J, Ensign LM. Mucus-penetrating budesonide nanosuspension enema for local treatment of inflammatory bowel disease. Biomaterials. 185: 97-105. PMID 30236840 DOI: 10.1016/j.biomaterials.2018.09.005  0.76
2018 Duncan GA, Kim N, Colon-Cortes Y, Rodriguez J, Mazur M, Birket SE, Rowe SM, West NE, Livraghi-Butrico A, Boucher RC, Hanes J, Aslanidi G, Suk JS. An Adeno-Associated Viral Vector Capable of Penetrating the Mucus Barrier to Inhaled Gene Therapy. Molecular Therapy. Methods & Clinical Development. 9: 296-304. PMID 30038933 DOI: 10.1016/j.omtm.2018.03.006  0.88
2018 Osman G, Rodriguez J, Chan SY, Chisholm J, Duncan G, Kim N, Tatler AL, Shakesheff KM, Hanes J, Suk JS, Dixon JE. PEGylated enhanced cell penetrating peptide nanoparticles for lung gene therapy. Journal of Controlled Release : Official Journal of the Controlled Release Society. 285: 35-45. PMID 30004000 DOI: 10.1016/j.jconrel.2018.07.001  0.88
2018 Bandeira E, Oliveira H, Silva JD, Menna-Barreto RFS, Takyia CM, Suk JS, Witwer KW, Paulaitis ME, Hanes J, Rocco PRM, Morales MM. Therapeutic effects of adipose-tissue-derived mesenchymal stromal cells and their extracellular vesicles in experimental silicosis. Respiratory Research. 19: 104. PMID 29843724 DOI: 10.1186/s12931-018-0802-3  0.88
2018 Hoang T, Date AA, Ortiz Ortiz J, Young TW, Bensouda S, Xiao P, Marzinke M, Rohan L, Fuchs EJ, Hendrix C, Gumber S, Villinger F, Cone RA, Hanes J, Ensign LM. Development of rectal enema as microbicide (DREAM): Preclinical progressive selection of a tenofovir prodrug enema. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 29802984 DOI: 10.1016/j.ejpb.2018.05.030  0.76
2018 Pitha I, Kimball EC, Oglesby EN, Pease ME, Fu J, Schaub J, Kim YC, Hu Q, Hanes J, Quigley HA. Sustained Dorzolamide Release Prevents Axonal and Retinal Ganglion Cell Loss in a Rat Model of IOP-Glaucoma. Translational Vision Science & Technology. 7: 13. PMID 29616152 DOI: 10.1167/tvst.7.2.13  0.84
2018 Lu HD, Pearson E, Ristroph KD, Duncan GA, Ensign LM, Soo Suk J, Hanes J, Prud'homme RK. Pseudomonas aeruginosa Pyocyanin Production Reduced by Quorum-Sensing Inhibiting Nanocarriers. International Journal of Pharmaceutics. PMID 29608955 DOI: 10.1016/j.ijpharm.2018.03.058  0.76
2018 Huang D, Chen YS, Xu Q, Hanes J, Rupenthal ID. Effects of enzymatic degradation on dynamic mechanical properties of the vitreous and intravitreal nanoparticle mobility. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 118: 124-133. PMID 29574081 DOI: 10.1016/j.ejps.2018.03.023  0.76
2017 Patil HP, Freches D, Karmani L, Duncan GA, Ucakar B, Suk JS, Hanes J, Gallez B, Vanbever R. Fate of PEGylated antibody fragments following delivery to the lungs: Influence of delivery site, PEG size and lung inflammation. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 29247664 DOI: 10.1016/j.jconrel.2017.12.009  0.88
2017 Xiao P, Gumber S, Marzinke MA, Date AA, Hoang T, Hanes J, Ensign LM, Wang L, Rohan L, Fuchs EJ, Hendrix C, Villinger F. Hypo-osmolar formulation of TFV enema promotes uptake and metabolism of TFV in tissues and leading to prevention of SHIV/SIV infection. Antimicrobial Agents and Chemotherapy. PMID 29084755 DOI: 10.1128/AAC.01644-17  0.76
2017 Kates M, Date A, Yoshida T, Afzal U, Kanvinde P, Babu T, Sopko NA, Matsui H, Hahn NM, McConkey DJ, Baras AS, Hanes J, Ensign L, Bivalacqua TJ. Preclincial Evaluation of Intravesical Cisplatin Nanoparticles for Non-Muscle-Invasive Bladder Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28808039 DOI: 10.1158/1078-0432.CCR-17-1082  0.56
2017 Huang X, Chisholm J, Zhuang J, Xiao Y, Duncan G, Chen X, Suk JS, Hanes J. Protein nanocages that penetrate airway mucus and tumor tissue. Proceedings of the National Academy of Sciences of the United States of America. PMID 28739953 DOI: 10.1073/pnas.1705407114  0.88
2017 Zhang C, Mastorakos P, Sobral M, Berry S, Song E, Nance E, Eberhart CG, Hanes J, Suk JS. Strategies to enhance the distribution of nanotherapeutics in the brain. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28739449 DOI: 10.1016/j.jconrel.2017.07.028  0.88
2017 Cui H, Hanes J. NanoDDS 2016: The 14th International Nanomedicine and Drug Delivery Symposium. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28734902 DOI: 10.1016/j.jconrel.2017.07.022  1
2017 Mastorakos P, Zhang C, Song E, Kim YE, Park HW, Berry S, Choi WK, Hanes J, Suk JS. Biodegradable brain-penetrating DNA nanocomplexes and their use to treat malignant brain tumors. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28694032 DOI: 10.1016/j.jconrel.2017.07.009  0.88
2017 Schuster BS, Allan DB, Kays JC, Hanes J, Leheny RL. Photoactivatable fluorescent probes reveal heterogeneous nanoparticle permeation through biological gels at multiple scales. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28578189 DOI: 10.1016/j.jconrel.2017.05.035  0.64
2017 Mead BP, Kim N, Miller GW, Hodges D, Mastorakos P, Klibanov AL, Mandell JW, Hirsh J, Suk JS, Hanes J, Price RJ. Novel focused ultrasound gene therapy approach non-invasively restores dopaminergic neuron function in a rat Parkinson's disease model. Nano Letters. PMID 28511006 DOI: 10.1021/acs.nanolett.7b00616  0.88
2017 Schneider CS, Xu Q, Boylan NJ, Chisholm J, Tang BC, Schuster BS, Henning A, Ensign LM, Lee E, Adstamongkonkul P, Simons BW, Wang SS, Gong X, Yu T, Boyle MP, ... ... Hanes J, et al. Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation. Science Advances. 3: e1601556. PMID 28435870 DOI: 10.1126/sciadv.1601556  0.88
2017 White DT, Sengupta S, Saxena MT, Xu Q, Hanes J, Ding D, Ji H, Mumm JS. Immunomodulation-accelerated neuronal regeneration following selective rod photoreceptor cell ablation in the zebrafish retina. Proceedings of the National Academy of Sciences of the United States of America. PMID 28416692 DOI: 10.1073/pnas.1617721114  0.76
2017 Timbie KF, Afzal U, Date A, Zhang C, Song J, Wilson Miller G, Suk JS, Hanes J, Price RJ. MR image-guided delivery of cisplatin-loaded brain-penetrating nanoparticles to invasive glioma with focused ultrasound. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28288892 DOI: 10.1016/j.jconrel.2017.03.017  0.88
2017 Zhang C, Nance EA, Mastorakos P, Chisholm J, Berry S, Eberhart C, Tyler B, Brem H, Suk JS, Hanes J. Convection enhanced delivery of cisplatin-loaded brain penetrating nanoparticles cures malignant glioma in rats. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28279797 DOI: 10.1016/j.jconrel.2017.03.007  0.88
2017 Kashiwabuchi F, Parikh KS, Omiadze R, Zhang S, Luo L, Patel HV, Xu Q, Ensign LM, Mao HQ, Hanes J, McDonnell PJ. Development of Absorbable, Antibiotic-Eluting Sutures for Ophthalmic Surgery. Translational Vision Science & Technology. 6: 1. PMID 28083445 DOI: 10.1167/tvst.6.1.1  0.76
2016 Leite Nascimento T, Hillaireau H, Vergnaud J, Rivano M, Deloménie C, Courilleau D, Arpicco S, Suk JS, Hanes J, Fattal E. Hyaluronic acid-conjugated lipoplexes for targeted delivery of siRNA in a murine metastatic lung cancer model. International Journal of Pharmaceutics. 514: 103-111. PMID 27863652 DOI: 10.1016/j.ijpharm.2016.06.125  0.88
2016 Duncan GA, Jung J, Joseph A, Thaxton AL, West NE, Boyle MP, Hanes J, Suk JS. Microstructural alterations of sputum in cystic fibrosis lung disease. Jci Insight. 1: e88198. PMID 27812540 DOI: 10.1172/jci.insight.88198  0.88
2016 Hanes J, Ensign LM, Kannan R, Suk JS. North America special issue Part II. Journal of Controlled Release : Official Journal of the Controlled Release Society. 240: 1. PMID 27725132 DOI: 10.1016/j.jconrel.2016.09.027  0.88
2016 Yu T, Chisholm J, Choi WJ, Anonuevo A, Pulicare S, Zhong W, Chen M, Fridley C, Lai SK, Ensign LM, Suk JS, Hanes J. Mucus-Penetrating Nanosuspensions for Enhanced Delivery of Poorly Soluble Drugs to Mucosal Surfaces. Advanced Healthcare Materials. PMID 27717163 DOI: 10.1002/adhm.201600599  1
2016 Duncan GA, Jung J, Hanes J, Soo Suk J. The Mucus Barrier to Inhaled Gene Therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 27646604 DOI: 10.1038/mt.2016.182  0.48
2016 Berry S, Mastorakos P, Zhang C, Song E, Patel H, Suk JS, Hanes J. Enhancing Intracranial Delivery of Clinically Relevant Non-viral Gene Vectors. Rsc Advances. 48: 41665-41674. PMID 27642512 DOI: 10.1039/C6RA01546H  1
2016 Chu KK, Mojahed D, Fernandez CM, Li Y, Liu L, Wilsterman EJ, Diephuis B, Birket SE, Bowers H, Martin Solomon G, Schuster BS, Hanes J, Rowe SM, Tearney GJ. Particle-Tracking Microrheology Using Micro-Optical Coherence Tomography. Biophysical Journal. 111: 1053-1063. PMID 27602733 DOI: 10.1016/j.bpj.2016.07.020  0.64
2016 Elgogary A, Xu Q, Poore B, Alt J, Zimmermann SC, Zhao L, Fu J, Chen B, Xia S, Liu Y, Neisser M, Nguyen C, Lee R, Park JK, Reyes J, ... ... Hanes J, et al. Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 27559084 DOI: 10.1073/pnas.1611406113  1
2016 Fu J, Sun F, Liu W, Liu Y, Gedam M, Hu Q, Fridley C, Quigley HA, Hanes J, Pitha IF. Subconjunctival delivery of dorzolamide-loaded poly(ether-anhydride) microparticles produces sustained lowering of intraocular pressure in rabbits. Molecular Pharmaceutics. PMID 27336794 DOI: 10.1021/acs.molpharmaceut.6b00343  0.36
2016 Date AA, Hanes J, Ensign LM. Nanoparticles for oral delivery: Design, evaluation and state-of-the-art. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 27292178 DOI: 10.1016/j.jconrel.2016.06.016  0.32
2016 Kim N, Duncan GA, Hanes J, Suk JS. Barriers to inhaled gene therapy of obstructive lung diseases: A review. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 27196742 DOI: 10.1016/j.jconrel.2016.05.031  1
2016 Maisel K, Reddy M, Xu Q, Chattopadhyay S, Cone R, Ensign LM, Hanes J. Nanoparticles coated with high molecular weight PEG penetrate mucus and provide uniform vaginal and colorectal distribution in vivo. Nanomedicine (London, England). PMID 27171816 DOI: 10.2217/nnm-2016-0047  0.8
2016 Birket SE, Chu KK, Houser GH, Liu L, Fernandez CM, Solomon GM, Lin V, Shastry S, Mazur M, Sloane P, Hanes J, Grizzle WE, Sorscher EJ, Tearney GJ, Rowe SM. Combination Therapy with Cystic Fibrosis Transmembrane Conductance Regulator Modulators Augment the Airway Functional Microanatomy. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00395.2015. PMID 26968770 DOI: 10.1152/ajplung.00395.2015  0.36
2015 Mead BP, Mastorakos P, Suk JS, Klibanov AL, Hanes J, Price RJ. Targeted gene transfer to the brain via the delivery of brain-penetrating DNA nanoparticles with focused ultrasound. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 26732553 DOI: 10.1016/j.jconrel.2015.12.034  0.32
2015 Oh Y, Park O, Swierczewska M, Hamilton JP, Park JS, Kim TH, Lim SM, Eom H, Jo DG, Lee CE, Kechrid R, Mastorakos P, Zhang C, Hahn SK, Jeon OC, ... ... Hanes J, et al. Systemic PEGylated TRAIL treatment ameliorates liver cirrhosis in rats by eliminating activated hepatic stellate cells. Hepatology (Baltimore, Md.). PMID 26710118 DOI: 10.1002/hep.28432  0.32
2015 Mastorakos P, Song E, Zhang C, Berry S, Park HW, Kim YE, Park JS, Lee S, Suk JS, Hanes J. Biodegradable DNA Nanoparticles that Provide Widespread Gene Delivery in the Brain. Small (Weinheim An Der Bergstrasse, Germany). PMID 26680637 DOI: 10.1002/smll.201502554  0.32
2015 Hanes J, Ensign L, Kannan R, Soo Suk J. Editorial. Journal of Controlled Release : Official Journal of the Controlled Release Society. 219: 1. PMID 26590704 DOI: 10.1016/j.jconrel.2015.10.057  0.48
2015 Suk JS, Xu Q, Kim N, Hanes J, Ensign LM. PEGylation as a strategy for improving nanoparticle-based drug and gene delivery. Advanced Drug Delivery Reviews. PMID 26456916 DOI: 10.1016/j.addr.2015.09.012  1
2015 Mitragotri S, Hanes J. Journal of Drug Targeting Life Time Achievement Award for Prof. Robert Langer. Journal of Drug Targeting. 23: 579. PMID 26453155 DOI: 10.3109/1061186X.2015.1054830  1
2015 Xu Q, Ensign LM, Boylan NJ, Schön A, Gong X, Yang JC, Lamb NW, Cai S, Yu T, Freire E, Hanes J. Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus ex Vivo and Distribution in Vivo. Acs Nano. 9: 9217-27. PMID 26301576 DOI: 10.1021/acsnano.5b03876  1
2015 Mastorakos P, da Silva AL, Chisholm J, Song E, Choi WK, Boyle MP, Morales MM, Hanes J, Suk JS. Highly compacted biodegradable DNA nanoparticles capable of overcoming the mucus barrier for inhaled lung gene therapy. Proceedings of the National Academy of Sciences of the United States of America. PMID 26124127 DOI: 10.1073/pnas.1502281112  1
2015 Maisel K, Chattopadhyay S, Moench T, Hendrix C, Cone R, Ensign LM, Hanes J. Enema ion compositions for enhancing colorectal drug delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 209: 280-7. PMID 25937321 DOI: 10.1016/j.jconrel.2015.04.040  1
2015 Schuster BS, Ensign LM, Allan DB, Suk JS, Hanes J. Particle tracking in drug and gene delivery research: State-of-the-art applications and methods. Advanced Drug Delivery Reviews. PMID 25858664 DOI: 10.1016/j.addr.2015.03.017  1
2015 Zhang F, Mastorakos P, Mishra MK, Mangraviti A, Hwang L, Zhou J, Hanes J, Brem H, Olivi A, Tyler B, Kannan RM. Uniform brain tumor distribution and tumor associated macrophage targeting of systemically administered dendrimers. Biomaterials. 52: 507-16. PMID 25818456 DOI: 10.1016/j.biomaterials.2015.02.053  1
2015 Mastorakos P, Zhang C, Berry S, Oh Y, Lee S, Eberhart CG, Woodworth GF, Suk JS, Hanes J. Highly PEGylated DNA Nanoparticles Provide Uniform and Widespread Gene Transfer in the Brain. Advanced Healthcare Materials. 4: 1023-33. PMID 25761435 DOI: 10.1002/adhm.201400800  1
2015 Lu HD, Spiegel AC, Hurley A, Perez LJ, Maisel K, Ensign LM, Hanes J, Bassler BL, Semmelhack MF, Prud'homme RK. Modulating Vibrio cholerae quorum-sensing-controlled communication using autoinducer-loaded nanoparticles. Nano Letters. 15: 2235-41. PMID 25651002 DOI: 10.1021/acs.nanolett.5b00151  1
2015 Pan Q, Xu Q, Boylan NJ, Lamb NW, Emmert DG, Yang JC, Tang L, Heflin T, Alwadani S, Eberhart CG, Stark WJ, Hanes J. Corticosteroid-loaded biodegradable nanoparticles for prevention of corneal allograft rejection in rats. Journal of Controlled Release : Official Journal of the Controlled Release Society. 201: 32-40. PMID 25576786 DOI: 10.1016/j.jconrel.2015.01.009  1
2015 Schneider CS, Perez JG, Cheng E, Zhang C, Mastorakos P, Hanes J, Winkles JA, Woodworth GF, Kim AJ. Minimizing the non-specific binding of nanoparticles to the brain enables active targeting of Fn14-positive glioblastoma cells. Biomaterials. 42: 42-51. PMID 25542792 DOI: 10.1016/j.biomaterials.2014.11.054  1
2015 Li Y, San BH, Kessler JL, Kim JH, Xu Q, Hanes J, Yu SM. Non-covalent photo-patterning of gelatin matrices using caged collagen mimetic peptides. Macromolecular Bioscience. 15: 52-62. PMID 25476588 DOI: 10.1002/mabi.201400436  1
2015 Yu T, Chan KW, Anonuevo A, Song X, Schuster BS, Chattopadhyay S, Xu Q, Oskolkov N, Patel H, Ensign LM, van Zjil PC, McMahon MT, Hanes J. Liposome-based mucus-penetrating particles (MPP) for mucosal theranostics: demonstration of diamagnetic chemical exchange saturation transfer (diaCEST) magnetic resonance imaging (MRI). Nanomedicine : Nanotechnology, Biology, and Medicine. 11: 401-5. PMID 25461289 DOI: 10.1016/j.nano.2014.09.019  0.76
2015 Maisel K, Ensign L, Reddy M, Cone R, Hanes J. Effect of surface chemistry on nanoparticle interaction with gastrointestinal mucus and distribution in the gastrointestinal tract following oral and rectal administration in the mouse. Journal of Controlled Release : Official Journal of the Controlled Release Society. 197: 48-57. PMID 25449804 DOI: 10.1016/j.jconrel.2014.10.026  1
2015 Mastorakos P, Kambhampati SP, Mishra MK, Wu T, Song E, Hanes J, Kannan RM. Hydroxyl PAMAM dendrimer-based gene vectors for transgene delivery to human retinal pigment epithelial cells. Nanoscale. 7: 3845-56. PMID 25213606 DOI: 10.1039/c4nr04284k  1
2014 Kim AJ, Woodworth GF, Boylan NJ, Suk JS, Hanes J. Highly compacted pH-responsive DNA nanoparticles mediate transgene silencing in experimental glioma. Journal of Materials Chemistry. B, Materials For Biology and Medicine. 2: 8165-8173. PMID 25485114 DOI: 10.1039/C4TB00559G  1
2014 Birjiniuk A, Billings N, Nance E, Hanes J, Ribbeck K, Doyle PS. Single particle tracking reveals spatial and dynamic organization of the E. coli biofilm matrix. New Journal of Physics. 16: 085014. PMID 25414591 DOI: 10.1088/1367-2630/16/8/085014  1
2014 Akgul Y, Word RA, Ensign LM, Yamaguchi Y, Lydon J, Hanes J, Mahendroo M. Hyaluronan in cervical epithelia protects against infection-mediated preterm birth. The Journal of Clinical Investigation. 124: 5481-9. PMID 25384213 DOI: 10.1172/JCI78765  0.76
2014 Ensign LM, Lai SK, Wang YY, Yang M, Mert O, Hanes J, Cone R. Pretreatment of human cervicovaginal mucus with pluronic F127 enhances nanoparticle penetration without compromising mucus barrier properties to herpes simplex virus. Biomacromolecules. 15: 4403-9. PMID 25347518 DOI: 10.1021/bm501419z  1
2014 Nance E, Zhang C, Shih TY, Xu Q, Schuster BS, Hanes J. Brain-penetrating nanoparticles improve paclitaxel efficacy in malignant glioma following local administration. Acs Nano. 8: 10655-64. PMID 25259648 DOI: 10.1021/nn504210g  1
2014 Pan-In P, Wanichwecharungruang S, Hanes J, Kim AJ. Cellular trafficking and anticancer activity of Garcinia mangostana extract-encapsulated polymeric nanoparticles. International Journal of Nanomedicine. 9: 3677-86. PMID 25125977 DOI: 10.2147/IJN.S66511  1
2014 Woodworth GF, Dunn GP, Nance EA, Hanes J, Brem H. Emerging insights into barriers to effective brain tumor therapeutics. Frontiers in Oncology. 4: 126. PMID 25101239 DOI: 10.3389/fonc.2014.00126  1
2014 Yang M, Lai SK, Yu T, Wang YY, Happe C, Zhong W, Zhang M, Anonuevo A, Fridley C, Hung A, Fu J, Hanes J. Nanoparticle penetration of human cervicovaginal mucus: the effect of polyvinyl alcohol. Journal of Controlled Release : Official Journal of the Controlled Release Society. 192: 202-8. PMID 25090196 DOI: 10.1016/j.jconrel.2014.07.045  1
2014 Birket SE, Chu KK, Liu L, Houser GH, Diephuis BJ, Wilsterman EJ, Dierksen G, Mazur M, Shastry S, Li Y, Watson JD, Smith AT, Schuster BS, Hanes J, Grizzle WE, et al. A functional anatomic defect of the cystic fibrosis airway. American Journal of Respiratory and Critical Care Medicine. 190: 421-32. PMID 25029666 DOI: 10.1164/rccm.201404-0670OC  1
2014 Nance E, Timbie K, Miller GW, Song J, Louttit C, Klibanov AL, Shih TY, Swaminathan G, Tamargo RJ, Woodworth GF, Hanes J, Price RJ. Non-invasive delivery of stealth, brain-penetrating nanoparticles across the blood-brain barrier using MRI-guided focused ultrasound. Journal of Controlled Release : Official Journal of the Controlled Release Society. 189: 123-32. PMID 24979210 DOI: 10.1016/j.jconrel.2014.06.031  1
2014 Schuster BS, Kim AJ, Kays JC, Kanzawa MM, Guggino WB, Boyle MP, Rowe SM, Muzyczka N, Suk JS, Hanes J. Overcoming the cystic fibrosis sputum barrier to leading adeno-associated virus gene therapy vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1484-93. PMID 24869933 DOI: 10.1038/mt.2014.89  1
2014 Ensign LM, Cone R, Hanes J. Nanoparticle-based drug delivery to the vagina: a review. Journal of Controlled Release : Official Journal of the Controlled Release Society. 190: 500-14. PMID 24830303 DOI: 10.1016/j.jconrel.2014.04.033  1
2014 Yang M, Yu T, Wood J, Wang YY, Tang BC, Zeng Q, Simons BW, Fu J, Chuang CM, Lai SK, Wu TC, Hung CF, Hanes J. Intraperitoneal delivery of paclitaxel by poly(ether-anhydride) microspheres effectively suppresses tumor growth in a murine metastatic ovarian cancer model. Drug Delivery and Translational Research. 4: 203-9. PMID 24816829 DOI: 10.1007/s13346-013-0190-7  1
2014 Pease ME, Oglesby EN, Cone-Kimball E, Jefferys JL, Steinhart MR, Kim AJ, Hanes J, Quigley HA. Scleral permeability varies by mouse strain and is decreased by chronic experimental glaucoma. Investigative Ophthalmology & Visual Science. 55: 2564-73. PMID 24557355 DOI: 10.1167/iovs.13-13327  1
2014 da Silva AL, Martini SV, Abreu SC, Samary Cdos S, Diaz BL, Fernezlian S, de Sá VK, Capelozzi VL, Boylan NJ, Goya RG, Suk JS, Rocco PR, Hanes J, Morales MM. DNA nanoparticle-mediated thymulin gene therapy prevents airway remodeling in experimental allergic asthma. Journal of Controlled Release : Official Journal of the Controlled Release Society. 180: 125-33. PMID 24556417 DOI: 10.1016/j.jconrel.2014.02.010  1
2014 Chan KW, Yu T, Qiao Y, Liu Q, Yang M, Patel H, Liu G, Kinzler KW, Vogelstein B, Bulte JW, van Zijl PC, Hanes J, Zhou S, McMahon MT. A diaCEST MRI approach for monitoring liposomal accumulation in tumors. Journal of Controlled Release : Official Journal of the Controlled Release Society. 180: 51-9. PMID 24548481 DOI: 10.1016/j.jconrel.2014.02.005  1
2014 Suk JS, Kim AJ, Trehan K, Schneider CS, Cebotaru L, Woodward OM, Boylan NJ, Boyle MP, Lai SK, Guggino WB, Hanes J. Lung gene therapy with highly compacted DNA nanoparticles that overcome the mucus barrier. Journal of Controlled Release : Official Journal of the Controlled Release Society. 178: 8-17. PMID 24440664 DOI: 10.1016/j.jconrel.2014.01.007  1
2014 Yang M, Yu T, Wang YY, Lai SK, Zeng Q, Miao B, Tang BC, Simons BW, Ensign LM, Liu G, Chan KW, Juang CY, Mert O, Wood J, Fu J, ... ... Hanes J, et al. Vaginal delivery of paclitaxel via nanoparticles with non-mucoadhesive surfaces suppresses cervical tumor growth. Advanced Healthcare Materials. 3: 1044-52. PMID 24339398 DOI: 10.1002/adhm.201300519  1
2014 Ensign L, Xu Q, Tang B, Wang YY, Cone R, Hanes J. Optimization of mucus penetrating particles and vehicle composition for improved mucosal surface drug delivery Nanoscale Science and Engineering Forum 2013 - Core Programming Area At the 2013 Aiche Annual Meeting: Global Challenges For Engineering a Sustainable Future. 2-4.  1
2013 Wang YY, Lai SK, Ensign LM, Zhong W, Cone R, Hanes J. The microstructure and bulk rheology of human cervicovaginal mucus are remarkably resistant to changes in pH. Biomacromolecules. 14: 4429-35. PMID 24266646 DOI: 10.1021/bm401356q  1
2013 Iwase T, Fu J, Yoshida T, Muramatsu D, Miki A, Hashida N, Lu L, Oveson B, Lima e Silva R, Seidel C, Yang M, Connelly S, Shen J, Han B, Wu M, ... ... Hanes J, et al. Sustained delivery of a HIF-1 antagonist for ocular neovascularization. Journal of Controlled Release : Official Journal of the Controlled Release Society. 172: 625-33. PMID 24126220 DOI: 10.1016/j.jconrel.2013.10.008  0.84
2013 Ensign LM, Hoen TE, Maisel K, Cone RA, Hanes JS. Enhanced vaginal drug delivery through the use of hypotonic formulations that induce fluid uptake. Biomaterials. 34: 6922-9. PMID 23769419 DOI: 10.1016/j.biomaterials.2013.05.039  1
2013 Xu Q, Boylan NJ, Cai S, Miao B, Patel H, Hanes J. Scalable method to produce biodegradable nanoparticles that rapidly penetrate human mucus. Journal of Controlled Release : Official Journal of the Controlled Release Society. 170: 279-86. PMID 23751567 DOI: 10.1016/j.jconrel.2013.05.035  1
2013 Ensign LM, Henning A, Schneider CS, Maisel K, Wang YY, Porosoff MD, Cone R, Hanes J. Ex vivo characterization of particle transport in mucus secretions coating freshly excised mucosal tissues. Molecular Pharmaceutics. 10: 2176-82. PMID 23617606 DOI: 10.1021/mp400087y  1
2013 Kim AJ, Boylan NJ, Suk JS, Hwangbo M, Yu T, Schuster BS, Cebotaru L, Lesniak WG, Oh JS, Adstamongkonkul P, Choi AY, Kannan RM, Hanes J. Use of single-site-functionalized PEG dendrons to prepare gene vectors that penetrate human mucus barriers. Angewandte Chemie (International Ed. in English). 52: 3985-8. PMID 23460577 DOI: 10.1002/anie.201208556  1
2013 Welsbie DS, Yang Z, Ge Y, Mitchell KL, Zhou X, Martin SE, Berlinicke CA, Hackler L, Fuller J, Fu J, Cao LH, Han B, Auld D, Xue T, Hirai S, ... ... Hanes J, et al. Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death. Proceedings of the National Academy of Sciences of the United States of America. 110: 4045-50. PMID 23431148 DOI: 10.1073/pnas.1211284110  1
2013 Goldberg MS, Hook SS, Wang AZ, Bulte JW, Patri AK, Uckun FM, Cryns VL, Hanes J, Akin D, Hall JB, Gharkholo N, Mumper RJ. Biotargeted nanomedicines for cancer: six tenets before you begin. Nanomedicine (London, England). 8: 299-308. PMID 23394158 DOI: 10.2217/nnm.13.3  1
2013 Schuster BS, Suk JS, Woodworth GF, Hanes J. Nanoparticle diffusion in respiratory mucus from humans without lung disease. Biomaterials. 34: 3439-46. PMID 23384790 DOI: 10.1016/j.biomaterials.2013.01.064  1
2013 Xu Q, Boylan NJ, Suk JS, Wang YY, Nance EA, Yang JC, McDonnell PJ, Cone RA, Duh EJ, Hanes J. Nanoparticle diffusion in, and microrheology of, the bovine vitreous ex vivo. Journal of Controlled Release : Official Journal of the Controlled Release Society. 167: 76-84. PMID 23369761 DOI: 10.1016/j.jconrel.2013.01.018  1
2013 Chan KW, Liu G, Song X, Kim H, Yu T, Arifin DR, Gilad AA, Hanes J, Walczak P, van Zijl PC, Bulte JW, McMahon MT. MRI-detectable pH nanosensors incorporated into hydrogels for in vivo sensing of transplanted-cell viability. Nature Materials. 12: 268-75. PMID 23353626 DOI: 10.1038/nmat3525  1
2012 Kim AJ, Hanes J. The emergence of multiple particle tracking in intracellular trafficking of nanomedicines. Biophysical Reviews. 4: 83-92. PMID 28510091 DOI: 10.1007/s12551-012-0066-y  0.88
2012 Yu T, Wang YY, Yang M, Schneider C, Zhong W, Pulicare S, Choi WJ, Mert O, Fu J, Lai SK, Hanes J. Biodegradable mucus-penetrating nanoparticles composed of diblock copolymers of polyethylene glycol and poly(lactic-co-glycolic acid). Drug Delivery and Translational Research. 2. PMID 24205449 DOI: 10.1007/s13346-011-0048-9  1
2012 Ensign LM, Schneider C, Suk JS, Cone R, Hanes J. Mucus penetrating nanoparticles: biophysical tool and method of drug and gene delivery. Advanced Materials (Deerfield Beach, Fla.). 24: 3887-94. PMID 22988559 DOI: 10.1002/adma.201201800  1
2012 Nance EA, Woodworth GF, Sailor KA, Shih TY, Xu Q, Swaminathan G, Xiang D, Eberhart C, Hanes J. A dense poly(ethylene glycol) coating improves penetration of large polymeric nanoparticles within brain tissue. Science Translational Medicine. 4: 149ra119. PMID 22932224 DOI: 10.1126/scitranslmed.3003594  1
2012 Burke CW, Suk JS, Kim AJ, Hsiang YH, Klibanov AL, Hanes J, Price RJ. Markedly enhanced skeletal muscle transfection achieved by the ultrasound-targeted delivery of non-viral gene nanocarriers with microbubbles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 162: 414-21. PMID 22800583 DOI: 10.1016/j.jconrel.2012.07.005  1
2012 Matthaei M, Meng H, Bhutto I, Xu Q, Boelke E, Hanes J, Jun AS. Systematic assessment of microneedle injection into the mouse cornea. European Journal of Medical Research. 17: 19. PMID 22716296 DOI: 10.1186/2047-783X-17-19  1
2012 Ensign LM, Tang BC, Wang YY, Tse TA, Hoen T, Cone R, Hanes J. Mucus-penetrating nanoparticles for vaginal drug delivery protect against herpes simplex virus. Science Translational Medicine. 4: 138ra79. PMID 22700955 DOI: 10.1126/scitranslmed.3003453  1
2012 Navarrette CR, Sisson JH, Nance E, Allen-Gipson D, Hanes J, Wyatt TA. Particulate matter in cigarette smoke increases ciliary axoneme beating through mechanical stimulation. Journal of Aerosol Medicine and Pulmonary Drug Delivery. 25: 159-68. PMID 22280523 DOI: 10.1089/jamp.2011.0890  1
2012 Ensign LM, Cone R, Hanes J. Oral drug delivery with polymeric nanoparticles: the gastrointestinal mucus barriers. Advanced Drug Delivery Reviews. 64: 557-70. PMID 22212900 DOI: 10.1016/j.addr.2011.12.009  1
2012 Boylan NJ, Kim AJ, Suk JS, Adstamongkonkul P, Simons BW, Lai SK, Cooper MJ, Hanes J. Enhancement of airway gene transfer by DNA nanoparticles using a pH-responsive block copolymer of polyethylene glycol and poly-L-lysine. Biomaterials. 33: 2361-71. PMID 22182747 DOI: 10.1016/j.biomaterials.2011.11.080  1
2012 Suh J, An Y, Tang BC, Dempsey C, Huang F, Hanes J. Real-time gene delivery vector tracking in the endo-lysosomal pathway of live cells. Microscopy Research and Technique. 75: 691-7. PMID 22095650 DOI: 10.1002/jemt.21113  1
2012 Kim AJ, Boylan NJ, Suk JS, Lai SK, Hanes J. Non-degradative intracellular trafficking of highly compacted polymeric DNA nanoparticles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 158: 102-7. PMID 22079809 DOI: 10.1016/j.jconrel.2011.10.031  1
2012 Mert O, Lai SK, Ensign L, Yang M, Wang YY, Wood J, Hanes J. A poly(ethylene glycol)-based surfactant for formulation of drug-loaded mucus penetrating particles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 157: 455-60. PMID 21911015 DOI: 10.1016/j.jconrel.2011.08.032  1
2012 Boylan NJ, Suk JS, Lai SK, Jelinek R, Boyle MP, Cooper MJ, Hanes J. Highly compacted DNA nanoparticles with low MW PEG coatings: in vitro, ex vivo and in vivo evaluation. Journal of Controlled Release : Official Journal of the Controlled Release Society. 157: 72-9. PMID 21903145 DOI: 10.1016/j.jconrel.2011.08.031  1
2012 Jachak A, Lai SK, Hida K, Suk JS, Markovic N, Biswal S, Breysse PN, Hanes J. Transport of metal oxide nanoparticles and single-walled carbon nanotubes in human mucus. Nanotoxicology. 6: 614-22. PMID 21800953 DOI: 10.3109/17435390.2011.598244  1
2012 Kim AJ, Hanes J. The emergence of multiple particle tracking in intracellular trafficking of nanomedicines Biophysical Reviews. 4: 83-92. DOI: 10.1007/s12551-012-0066-y  1
2011 Suk JS, Boylan NJ, Trehan K, Tang BC, Schneider CS, Lin JG, Boyle MP, Zeitlin PL, Lai SK, Cooper MJ, Hanes J. N-acetylcysteine Enhances Cystic Fibrosis Sputum Penetration and Airway Gene Transfer by Highly Compacted DNA Nanoparticles. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1981-1989. PMID 28160651 DOI: 10.1038/mt.2011.160  1
2011 Labhasetwar V, Egashira K, Hanes J. Editorial. Drug Delivery and Translational Research. 1: 1. PMID 25787886 DOI: 10.1007/s13346-010-0013-z  1
2011 Suk JS, Boylan NJ, Trehan K, Tang BC, Schneider CS, Lin JM, Boyle MP, Zeitlin PL, Lai SK, Cooper MJ, Hanes J. N-acetylcysteine enhances cystic fibrosis sputum penetration and airway gene transfer by highly compacted DNA nanoparticles. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1981-9. PMID 21829177 DOI: 10.1038/mt.2011.160  1
2011 Wang YY, Lai SK, So C, Schneider C, Cone R, Hanes J. Mucoadhesive nanoparticles may disrupt the protective human mucus barrier by altering its microstructure. Plos One. 6: e21547. PMID 21738703 DOI: 10.1371/journal.pone.0021547  1
2011 Lai SK, Suk JS, Pace A, Wang YY, Yang M, Mert O, Chen J, Kim J, Hanes J. Drug carrier nanoparticles that penetrate human chronic rhinosinusitis mucus. Biomaterials. 32: 6285-90. PMID 21665271 DOI: 10.1016/j.biomaterials.2011.05.008  1
2011 Hida K, Lai SK, Suk JS, Won SY, Boyle MP, Hanes J. Common gene therapy viral vectors do not efficiently penetrate sputum from cystic fibrosis patients. Plos One. 6: e19919. PMID 21637751 DOI: 10.1371/journal.pone.0019919  1
2011 Suk JS, Lai SK, Boylan NJ, Dawson MR, Boyle MP, Hanes J. Rapid transport of muco-inert nanoparticles in cystic fibrosis sputum treated with N-acetyl cysteine. Nanomedicine (London, England). 6: 365-75. PMID 21385138 DOI: 10.2217/nnm.10.123  1
2011 Yang M, Lai SK, Wang YY, Zhong W, Happe C, Zhang M, Fu J, Hanes J. Biodegradable nanoparticles composed entirely of safe materials that rapidly penetrate human mucus. Angewandte Chemie (International Ed. in English). 50: 2597-600. PMID 21370345 DOI: 10.1002/anie.201006849  1
2011 Lai SK, Wang YY, Hida K, Cone R, Hanes J. Nanoparticles reveal that human cervicovaginal mucus is riddled with pores larger than viruses (Journal of Biological Chemistry (2010) 107, 2 (598-603) DOI: 10.1073/pnas.0911748107) Proceedings of the National Academy of Sciences of the United States of America. 108: 14371. DOI: 10.1073/pnas.1111693108  1
2010 Whaley KJ, Hanes J, Shattock R, Cone RA, Friend DR. Novel approaches to vaginal delivery and safety of microbicides: biopharmaceuticals, nanoparticles, and vaccines. Antiviral Research. 88: S55-66. PMID 21109069 DOI: 10.1016/j.antiviral.2010.09.006  1
2010 Aich U, Meledeo MA, Sampathkumar SG, Fu J, Jones MB, Weier CA, Chung SY, Tang BC, Yang M, Hanes J, Yarema KJ. Development of delivery methods for carbohydrate-based drugs: controlled release of biologically-active short chain fatty acid-hexosamine analogs. Glycoconjugate Journal. 27: 445-59. PMID 20458533 DOI: 10.1007/s10719-010-9292-3  1
2010 Hida K, Won SY, Di Pasquale G, Hanes J, Chiorini JA, Ostermeier M. Sites in the AAV5 capsid tolerant to deletions and tandem duplications. Archives of Biochemistry and Biophysics. 496: 1-8. PMID 20102698 DOI: 10.1016/j.abb.2010.01.009  1
2010 Lai SK, Wang YY, Hida K, Cone R, Hanes J. Nanoparticles reveal that human cervicovaginal mucus is riddled with pores larger than viruses. Proceedings of the National Academy of Sciences of the United States of America. 107: 598-603. PMID 20018745 DOI: 10.1073/pnas.0911748107  1
2010 Tang BC, Fu J, Watkins DN, Hanes J. Enhanced efficacy of local etoposide delivery by poly(ether-anhydride) particles against small cell lung cancer in vivo. Biomaterials. 31: 339-44. PMID 19796810 DOI: 10.1016/j.biomaterials.2009.09.033  1
2009 Tang BC, Dawson M, Lai SK, Wang YY, Suk JS, Yang M, Zeitlin P, Boyle MP, Fu J, Hanes J. Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier. Proceedings of the National Academy of Sciences of the United States of America. 106: 19268-73. PMID 19901335 DOI: 10.1073/pnas.0905998106  1
2009 Lai SK, Hida K, Shukair S, Wang YY, Figueiredo A, Cone R, Hope TJ, Hanes J. Human immunodeficiency virus type 1 is trapped by acidic but not by neutralized human cervicovaginal mucus. Journal of Virology. 83: 11196-200. PMID 19692470 DOI: 10.1128/JVI.01899-08  1
2009 Hanes J, Demeester J. Drug and gene delivery to mucosal tissues: the mucus barrier. Preface. Advanced Drug Delivery Reviews. 61: 73-4. PMID 19244608 DOI: 10.1016/j.addr.2009.01.002  1
2009 Suk JS, Lai SK, Wang YY, Ensign LM, Zeitlin PL, Boyle MP, Hanes J. The penetration of fresh undiluted sputum expectorated by cystic fibrosis patients by non-adhesive polymer nanoparticles. Biomaterials. 30: 2591-7. PMID 19176245 DOI: 10.1016/j.biomaterials.2008.12.076  1
2009 Lai SK, Wang YY, Cone R, Wirtz D, Hanes J. Altering mucus rheology to "solidify" human mucus at the nanoscale. Plos One. 4: e4294. PMID 19173002 DOI: 10.1371/journal.pone.0004294  1
2009 Lai SK, Wang YY, Wirtz D, Hanes J. Micro- and macrorheology of mucus. Advanced Drug Delivery Reviews. 61: 86-100. PMID 19166889 DOI: 10.1016/j.addr.2008.09.012  1
2009 Lai SK, Wang YY, Hanes J. Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues. Advanced Drug Delivery Reviews. 61: 158-71. PMID 19133304 DOI: 10.1016/j.addr.2008.11.002  1
2008 Wang YY, Lai SK, Suk JS, Pace A, Cone R, Hanes J. Addressing the PEG mucoadhesivity paradox to engineer nanoparticles that "slip" through the human mucus barrier. Angewandte Chemie (International Ed. in English). 47: 9726-9. PMID 18979480 DOI: 10.1002/anie.200803526  1
2008 Lai SK, Hanes J. Real-time multiple particle tracking of gene nanocarriers in complex biological environments. Methods in Molecular Biology (Clifton, N.J.). 434: 81-97. PMID 18470640 DOI: 10.1007/978-1-60327-248-3_6  1
2008 Deosarkar SP, Malgor R, Fu J, Kohn LD, Hanes J, Goetz DJ. Polymeric particles conjugated with a ligand to VCAM-1 exhibit selective, avid, and focal adhesion to sites of atherosclerosis. Biotechnology and Bioengineering. 101: 400-7. PMID 18428114 DOI: 10.1002/bit.21885  1
2008 Lai SK, Hida K, Chen C, Hanes J. Characterization of the intracellular dynamics of a non-degradative pathway accessed by polymer nanoparticles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 125: 107-11. PMID 18053606 DOI: 10.1016/j.jconrel.2007.10.015  1
2007 Suh J, Choy KL, Lai SK, Suk JS, Tang BC, Prabhu S, Hanes J. PEGylation of nanoparticles improves their cytoplasmic transport. International Journal of Nanomedicine. 2: 735-41. PMID 18203439  1
2007 Wei C, Liu N, Xu P, Heller M, Tomalia DA, Haynie DT, Chang EH, Wang K, Lee YS, Lyubchenko YL, Bawa R, Tian R, Hanes J, Pun S, Meiners JC, et al. From bench to bedside: successful translational nanomedicine: highlights of the Third Annual Meeting of the American Academy of Nanomedicine. Nanomedicine : Nanotechnology, Biology, and Medicine. 3: 322-31. PMID 18068093 DOI: 10.1016/j.nano.2007.10.005  1
2007 Hida K, Hanes J, Ostermeier M. Directed evolution for drug and nucleic acid delivery. Advanced Drug Delivery Reviews. 59: 1562-78. PMID 17933418 DOI: 10.1016/j.addr.2007.08.022  1
2007 Lai SK, Hida K, Man ST, Chen C, Machamer C, Schroer TA, Hanes J. Privileged delivery of polymer nanoparticles to the perinuclear region of live cells via a non-clathrin, non-degradative pathway. Biomaterials. 28: 2876-84. PMID 17363053 DOI: 10.1016/j.biomaterials.2007.02.021  1
2007 Suk JS, Suh J, Lai SK, Hanes J. Quantifying the intracellular transport of viral and nonviral gene vectors in primary neurons. Experimental Biology and Medicine (Maywood, N.J.). 232: 461-9. PMID 17327481  1
2007 Lai SK, O'Hanlon DE, Harrold S, Man ST, Wang YY, Cone R, Hanes J. Rapid transport of large polymeric nanoparticles in fresh undiluted human mucus. Proceedings of the National Academy of Sciences of the United States of America. 104: 1482-7. PMID 17244708 DOI: 10.1073/pnas.0608611104  1
2006 Wei C, Lyubchenko YL, Ghandehari H, Hanes J, Stebe KJ, Mao HQ, Haynie DT, Tomalia DA, Foldvari M, Monteiro-Riviere N, Simeonova P, Nie S, Mori H, Gilbert SP, Needham D, et al. New technology and clinical applications of nanomedicine: highlights of the second annual meeting of the American Academy of Nanomedicine (Part I). Nanomedicine : Nanotechnology, Biology, and Medicine. 2: 253-63. PMID 17292151 DOI: 10.1016/j.nano.2006.11.001  1
2006 Suk JS, Suh J, Choy K, Lai SK, Fu J, Hanes J. Gene delivery to differentiated neurotypic cells with RGD and HIV Tat peptide functionalized polymeric nanoparticles. Biomaterials. 27: 5143-50. PMID 16769110 DOI: 10.1016/j.biomaterials.2006.05.013  1
2005 Fiegel J, Jin F, Hanes J, Stebe K. Wetting of a particle in a thin film. Journal of Colloid and Interface Science. 291: 507-14. PMID 15946673 DOI: 10.1016/j.jcis.2005.05.014  1
2005 Sakhalkar HS, Hanes J, Fu J, Benavides U, Malgor R, Borruso CL, Kohn LD, Kurjiaka DT, Goetz DJ. Enhanced adhesion of ligand-conjugated biodegradable particles to colitic venules. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 792-4. PMID 15764649 DOI: 10.1096/fj.04-2668fje  1
2005 Suh J, Dawson M, Hanes J. Real-time multiple-particle tracking: applications to drug and gene delivery. Advanced Drug Delivery Reviews. 57: 63-78. PMID 15518921 DOI: 10.1016/j.addr.2004.06.001  1
2005 Lai SK, Hanes J. Size of nanoparticles affect intracellular trafficking in live cells Aiche Annual Meeting, Conference Proceedings. 14258.  1
2005 Lai SK, Man ST, Fu J, Hanes J. Real-time tracking of the intracellular path of pla-peg polymeric micelles in live cells Aiche Annual Meeting, Conference Proceedings. 13961.  1
2005 Lai SK, Fu J, Man ST, Hanes J. Doxorubicin-loaded transferrin-targeted polymeric micelles rapidly enter cancer cells and accumulate near the cell nucleus Aiche Annual Meeting, Conference Proceedings. 14370.  1
2005 Har-El YE, Van Zanten JH, Hanes J. Stability of high density Pei/Vegf DNA nanocomplexes in physiological fluids Aiche Annual Meeting, Conference Proceedings. 14304.  1
2005 Lai SK, O'Hanlon ED, Man ST, Cone R, Hanes J. Real-time transport of polymer nanoparticles in cervical vaginal mucus Aiche Annual Meeting, Conference Proceedings. 14298.  1
2004 Dawson M, Krauland E, Wirtz D, Hanes J. Transport of polymeric nanoparticle gene carriers in gastric mucus. Biotechnology Progress. 20: 851-7. PMID 15176891 DOI: 10.1021/bp0342553  1
2004 Fiegel J, Fu J, Hanes J. Poly(ether-anhydride) dry powder aerosols for sustained drug delivery in the lungs. Journal of Controlled Release : Official Journal of the Controlled Release Society. 96: 411-23. PMID 15120898 DOI: 10.1016/j.jconrel.2004.02.018  1
2004 Suh J, Wirtz D, Hanes J. Real-time intracellular transport of gene nanocarriers studied by multiple particle tracking. Biotechnology Progress. 20: 598-602. PMID 15059007 DOI: 10.1021/bp034251y  1
2004 Li H, Yuan Z, Lam KY, Lee HP, Chen J, Hanes J, Fu J. Model development and numerical simulation of electric-stimulus-responsive hydrogels subject to an externally applied electric field. Biosensors & Bioelectronics. 19: 1097-107. PMID 15018965 DOI: 10.1016/j.bios.2003.10.004  0.84
2004 Fu J, Fiegel J, Hanes J. Synthesis and characterization of PEG-based ether-anhydride terpolymers: Novel polymers for controlled drug delivery Macromolecules. 37: 7174-7180. DOI: 10.1021/ma049853s  1
2004 Suh J, Hanes J. Immobilization of gene vectors in perinuclear region as potential intracellular barrier to efficient gene delivery Aiche Annual Meeting, Conference Proceedings. 8769-8770.  1
2004 Suk JS, Suh J, Hanes J. Cellular uptake and intracellular transport of viral and non-viral gene vectors in differentiated neurons affected in Parkinson's Disease Aiche Annual Meeting, Conference Proceedings. 1085-1086.  1
2004 An Y, Suh J, Hanes J. Tracking the intracellular path of fluorescently labeled DNA delivered by PEI nanocomplexes in live cells Aiche Annual Meeting, Conference Proceedings. 1095-1096.  1
2004 Choy K, Suh J, Hanes J. PEG improves intracellular transport of drug/gene carriers as revealed by real-time particle tracking Aiche Annual Meeting, Conference Proceedings. 1313.  1
2004 Dawson M, Wirtz D, Hanes J. Microscopic viscoelasticity of CF sputum determined by high-resolution nanoparticle tracking Aiche Annual Meeting, Conference Proceedings. 1315-1316.  1
2004 Dawson M, Wirtz D, Hanes J. Gene carriers modified with PEG demonstrate increased transport and stability in mucus as explored with high-resolution nanoparticle tracking Aiche Annual Meeting, Conference Proceedings. 6345.  1
2004 Suh J, An Y, Tang B, Suk JS, Hanes J. Real-time correlation of intracellular gene vector transport rates with biological location in live mesenchymal stem cells Aiche Annual Meeting, Conference Proceedings. 2187-2188.  1
2003 Li H, Yuan Z, Ng TY, Lee HP, Lam KY, Wang QX, Wu S, Fu J, Hanes J. Constitutive model development and micro-structural topology optimisation for nafion hydrogel membranes with ionic clustering. Journal of Biomaterials Science. Polymer Edition. 14: 1181-96. PMID 14768907  0.84
2003 Sakhalkar HS, Dalal MK, Salem AK, Ansari R, Fu J, Kiani MF, Kurjiaka DT, Hanes J, Shakesheff KM, Goetz DJ. Leukocyte-inspired biodegradable particles that selectively and avidly adhere to inflamed endothelium in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America. 100: 15895-900. PMID 14668435 DOI: 10.1073/pnas.2631433100  1
2003 Dawson M, Wirtz D, Hanes J. Enhanced viscoelasticity of human cystic fibrotic sputum correlates with increasing microheterogeneity in particle transport. The Journal of Biological Chemistry. 278: 50393-401. PMID 13679362 DOI: 10.1074/jbc.M309026200  1
2003 Fiegel J, Ehrhardt C, Schaefer UF, Lehr CM, Hanes J. Large porous particle impingement on lung epithelial cell monolayers--toward improved particle characterization in the lung. Pharmaceutical Research. 20: 788-96. PMID 12751635 DOI: 10.1023/A:1023441804464  1
2003 Suh J, Wirtz D, Hanes J. Efficient active transport of gene nanocarriers to the cell nucleus. Proceedings of the National Academy of Sciences of the United States of America. 100: 3878-82. PMID 12644705 DOI: 10.1073/pnas.0636277100  1
2002 Fu J, Fiegel J, Krauland E, Hanes J. New polymeric carriers for controlled drug delivery following inhalation or injection. Biomaterials. 23: 4425-33. PMID 12219833 DOI: 10.1016/S0142-9612(02)00182-5  1
2002 Ehrhardt C, Fiegel J, Fuchs S, Abu-Dahab R, Schaefer UF, Hanes J, Lehr CM. Drug absorption by the respiratory mucosa: cell culture models and particulate drug carriers. Journal of Aerosol Medicine : the Official Journal of the International Society For Aerosols in Medicine. 15: 131-9. PMID 12184863 DOI: 10.1089/089426802320282257  1
2002 Ehrhardt C, Kneuer C, Fiegel J, Hanes J, Schaefer UF, Kim KJ, Lehr CM. Influence of apical fluid volume on the development of functional intercellular junctions in the human epithelial cell line 16HBE14o-: implications for the use of this cell line as an in vitro model for bronchial drug absorption studies. Cell and Tissue Research. 308: 391-400. PMID 12107432 DOI: 10.1007/s00441-002-0548-5  1
2002 Suh J, Wirtz D, Hanes J. Real-time quantitation of intracellular polycation/DNA nanocomplex transport: Evidence for directed motion Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 548-549.  1
2002 Van Zanten JH, Har-El Y, Hanes J. Optimization of PEI/VEGF DNA polyplexes for potenital delivery from tissue engineering scaffolds Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 563-564.  1
2002 Fu J, Krauland E, Har-el YE, Hanes J. New degradable cationic polyesters for nonviral gene delivery Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 551-552.  1
1998 Hanes J, Chiba M, Langer R. Degradation of porous poly(anhydride-co-imide) microspheres and implications for controlled macromolecule delivery Biomaterials. 19: 163-172. PMID 9678864 DOI: 10.1016/S0142-9612(97)00221-4  1
1997 Batycky RP, Hanes J, Langer R, Edwards DA. A theoretical model of erosion and macromolecular drug release from biodegrading microspheres. Journal of Pharmaceutical Sciences. 86: 1464-77. PMID 9423163 DOI: 10.1021/js9604117  1
1997 Chiba M, Hanes J, Langer R. Controlled protein delivery from biodegradable tyrosine-containing poly(anhydride-co-imide) microspheres Biomaterials. 18: 893-901. PMID 9199758 DOI: 10.1016/S0142-9612(97)00027-6  1
1997 Hanes J, Cleland JL, Langer R. New advances in microsphere-based single-dose vaccines Advanced Drug Delivery Reviews. 28: 97-119. DOI: 10.1016/S0169-409X(97)00053-7  1
1997 Batycky RP, Hanes J, Langer R, Edwards DA. A theory of erosion and macromolecule release from biodegrading microspheres Proceedings of the Controlled Release Society. 167-168.  1
1997 Hanes J, Hildgen P, Batycky RP, Cleland JL, Edwards DA, Langer R. Porous poly(D,L-lactic-co-glycolic acid) microsphere degradation and release of macromolecules Proceedings of the Controlled Release Society. 1027-1028.  1
1996 Hanes J, Chiba M, Langer R. Synthesis and characterization of degradable anhydride-co-imide terpolymers containing trimellitylimido-L-tyrosine: Novel polymers for drug delivery Macromolecules. 29: 5279-5287.  1
1995 Hanes J, Chiba M, Langer R. Polymer microspheres for vaccine delivery Pharmaceutical Biotechnology. 6: 389-412. PMID 7551227  1
1994 Chiba M, Hanes J, Langer R. Polyanhydride microspheres as potential vaccine delivery systems Proceedings of the Controlled Release Society. 877-878.  1
1994 Hanes J, Chiba M, Langer R. Degradation and erosion of tyrosine-containing polyanhydrides: Implications for vaccine delivery Proceedings of the Controlled Release Society. 44-45.  1
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