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Erik L. Meredith, Ph.D. - Publications

Affiliations: 
2002 Brigham Young University, Provo, UT, United States 
Area:
Organic Chemistry, Pharmaceutical Chemistry
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16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Palacios DS, Meredith EL, Kawanami T, Adams CM, Chen X, Darsigny V, Palermo M, Baird D, George EL, Guy C, Hewett J, Tierney L, Thigale S, Wang L, Weihofen WA. Scaffold Morphing Identifies 3-Pyridyl Azetidine Ureas as Inhibitors of Nicotinamide Phosphoribosyltransferase (NAMPT). Acs Medicinal Chemistry Letters. 10: 1524-1529. PMID 31749905 DOI: 10.1021/Acsmedchemlett.9B00325  0.347
2018 Ehara T, Adams CM, Bevan D, Ji N, Meredith EL, Belanger DB, Powers J, Kato M, Solovay C, Liu D, Capparelli M, Bolduc P, Grob JE, Daniels MH, Ferrara L, et al. The Discovery of (S)-1-(6-(3-((4-(1-(Cyclopropanecarbonyl)piperidin-4-yl)-2-methylphenyl)amino)-2,3-dihydro-1H-inden-4-yl)pyridin-2-yl)-5-methyl-1H-pyrazole-4-carboxylic Acid, a Soluble Guanylate Cyclase Activator Specifically Designed for Topical Ocular Delivery as a Therapy for Glaucoma. Journal of Medicinal Chemistry. PMID 29498522 DOI: 10.1021/Acs.Jmedchem.8B00007  0.33
2017 Palacios DS, Meredith E, Kawanami T, Adams C, Chen X, Darsigny V, Geno E, Palermo M, Baird D, Boynton G, Busby SA, George EL, Guy C, Hewett J, Tierney L, et al. Structure based design of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors from a phenotypic screen. Bioorganic & Medicinal Chemistry Letters. PMID 29275937 DOI: 10.1016/J.Bmcl.2017.12.037  0.31
2016 Mainolfi N, Powers J, Meredith E, Elliott J, Gunderson KG, Poor S, Liu F, Anderson K. Core Replacements in a Potent Series of VEGFR-2 Inhibitors and Their Impact on Potency, Solubility, and hERG. Acs Medicinal Chemistry Letters. 7: 357-62. PMID 27096041 DOI: 10.1021/Acsmedchemlett.6B00018  0.362
2013 Meredith EL, Ksander G, Monovich LG, Papillon JP, Liu Q, Miranda K, Morris P, Rao C, Burgis R, Capparelli M, Hu QY, Singh A, Rigel DF, Jeng AY, Beil M, et al. Discovery and in Vivo Evaluation of Potent Dual CYP11B2 (Aldosterone Synthase) and CYP11B1 Inhibitors. Acs Medicinal Chemistry Letters. 4: 1203-7. PMID 24900631 DOI: 10.1021/Ml400324C  0.337
2012 Johnson L, Powers J, Ma F, Jendza K, Wang B, Meredith E, Mainolfi N. A Reliable Synthesis of 3-Amino-5-Alkyl and 5-Amino-3-Alkyl Isoxazoles Synthesis. 45: 171-173. DOI: 10.1055/S-0032-1317935  0.468
2010 Meredith EL, Beattie K, Burgis R, Capparelli M, Chapo J, Dipietro L, Gamber G, Enyedy I, Hood DB, Hosagrahara V, Jewell C, Koch KA, Lee W, Lemon DD, Mckinsey TA, et al. Identification of potent and selective amidobipyridyl inhibitors of protein kinase D Journal of Medicinal Chemistry. 53: 5422-5438. PMID 20684592 DOI: 10.1021/Jm100076W  0.329
2005 Andrus MB, Hicken EJ, Meredith EL. Chapter 2 Synthesis of geldanamycin using glycolate aldol reactions Strategies and Tactics in Organic Synthesis. 6: 38-70. DOI: 10.1016/S1874-6004(05)80025-5  0.741
2003 Andrus MB, Meredith EL, Hicken EJ, Simmons BL, Glancey RR, Ma W. Total synthesis of (+)-geldanamycin and (-)-o-quinogeldanamycin: asymmetric glycolate aldol reactions and biological evaluation. The Journal of Organic Chemistry. 68: 8162-9. PMID 14535799 DOI: 10.1021/Jo034870L  0.749
2003 Andrus MB, Hicken EJ, Meredith EL, Simmons BL, Cannon JF. Selective synthesis of the para-quinone region of geldanamycin. Organic Letters. 5: 3859-62. PMID 14535728 DOI: 10.1021/Ol035400G  0.721
2003 Andrus MB, Liu J, Meredith EL, Nartey E. Synthesis of resveratrol using a direct decarbonylative Heck approach from resorcylic acid Tetrahedron Letters. 44: 4819-4822. DOI: 10.1016/S0040-4039(03)01131-6  0.617
2002 Andrus MB, Meredith EL, Simmons BL, Soma Sekhar BB, Hicken EJ. Total synthesis of (+)-geldanamycin and (-)-o-quinogeldanamycin with use of asymmetric anti- and syn-glycolate aldol reactions. Organic Letters. 4: 3549-52. PMID 12323066 DOI: 10.1021/Ol0267432  0.745
2002 Andrus MB, Mendenhall KG, Meredith EL, Soma Sekhar BBV. Glycolate aldol reactions with boron enolates of bis-4-methoxyphenyl dioxanone Tetrahedron Letters. 43: 1789-1792. DOI: 10.1016/S0040-4039(02)00152-1  0.695
2001 Andrus MB, Meredith EL, Sekhar BB. Synthesis of the left-hand portion of geldanamycin using an anti glycolate aldol reaction. Organic Letters. 3: 259-62. PMID 11430049 DOI: 10.1021/Ol0068997  0.686
2001 Andrus MB, Soma Sekhar BBV, Turner TM, Meredith EL. Highly selective syn glycolate aldol reactions with boron enolates of Masamune norephedrine esters Tetrahedron Letters. 42: 7197-7201. DOI: 10.1016/S0040-4039(01)01521-0  0.752
2000 Andrus MB, Sekhar BB, Meredith EL, Dalley NK. Anti-selective glycolate aldol additions with an oxapyrone boron enolate. Organic Letters. 2: 3035-7. PMID 10986101 DOI: 10.1021/Ol0002166  0.698
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