| Year |
Citation |
Score |
| 2021 |
Duffel MW, Tuttle K, Lehmler HJ, Robertson LW. Human hepatic microsomal sulfatase catalyzes the hydrolysis of polychlorinated biphenyl sulfates: A potential mechanism for retention of hydroxylated PCBs. Environmental Toxicology and Pharmacology. 88: 103757. PMID 34688910 DOI: 10.1016/j.etap.2021.103757 |
0.367 |
|
| 2019 |
Sethi S, Morgan R, Feng W, Lin Y, Li X, Luna C, Koch M, Bansal R, Duffel MW, Puschner B, Zoeller TR, Lehmler HJ, Pessah IN, Lein PJ. Comparative analyses of the 12 most abundant PCB congeners detected in human maternal serum for activity at the thyroid hormone receptor and ryanodine receptor. Environmental Science & Technology. PMID 30821444 DOI: 10.1021/Acs.Est.9B00535 |
0.346 |
|
| 2018 |
Rodriguez EA, Vanle BC, Doorn JA, Lehmler HJ, Robertson LW, Duffel MW. Hydroxylated and sulfated metabolites of commonly observed airborne polychlorinated biphenyls display selective uptake and toxicity in N27, SH-SY5Y, and HepG2 cells. Environmental Toxicology and Pharmacology. 62: 69-78. PMID 29986280 DOI: 10.1016/J.Etap.2018.06.010 |
0.319 |
|
| 2018 |
Parker VS, Squirewell EJ, Lehmler HJ, Robertson LW, Duffel MW. Hydroxylated and sulfated metabolites of commonly occurring airborne polychlorinated biphenyls inhibit human steroid sulfotransferases SULT1E1 and SULT2A1. Environmental Toxicology and Pharmacology. 58: 196-201. PMID 29408762 DOI: 10.1016/J.Etap.2018.01.010 |
0.791 |
|
| 2018 |
Li X, Holland EB, Feng W, Zheng J, Dong Y, Pessah IN, Duffel MW, Robertson LW, Lehmler HJ. Authentication of synthetic environmental contaminants and their (bio)transformation products in toxicology: polychlorinated biphenyls as an example. Environmental Science and Pollution Research International. PMID 29322390 DOI: 10.1007/S11356-017-1162-0 |
0.315 |
|
| 2017 |
Dhakal K, Gadupudi GS, Lehmler HJ, Ludewig G, Duffel MW, Robertson LW. Sources and toxicities of phenolic polychlorinated biphenyls (OH-PCBs). Environmental Science and Pollution Research International. PMID 28744683 DOI: 10.1007/S11356-017-9694-X |
0.417 |
|
| 2016 |
Grimm FA, Lehmler HJ, Koh WX, DeWall J, Teesch LM, Hornbuckle KC, Thorne PS, Robertson LW, Duffel MW. Identification of a sulfate metabolite of PCB 11 in human serum. Environment International. PMID 27816204 DOI: 10.1016/J.Envint.2016.10.023 |
0.654 |
|
| 2016 |
Rodriguez EA, Li X, Lehmler HJ, Robertson LW, Duffel MW. Sulfation of lower chlorinated polychlorinated biphenyls increases their affinity for the major drug-binding sites of human serum albumin. Environmental Science & Technology. PMID 27116425 DOI: 10.1021/Acs.Est.6B00484 |
0.394 |
|
| 2016 |
Ekuase EJ, van 't Erve TJ, Rahaman A, Robertson LW, Duffel MW, Luthe G. Mechanistic insights into the specificity of human cytosolic sulfotransferase 2A1 (hSULT2A1) for hydroxylated polychlorinated biphenyls through the use of fluoro-tagged probes. Environmental Science and Pollution Research International. 23: 2119-27. PMID 26165989 DOI: 10.1007/S11356-015-4886-8 |
0.78 |
|
| 2015 |
Grimm FA, He X, Teesch LM, Lehmler HJ, Robertson LW, Duffel MW. Tissue Distribution, Metabolism, and Excretion of 3,3'-Dichloro-4'-sulfooxy-biphenyl in the Rat. Environmental Science & Technology. 49: 8087-95. PMID 26046945 DOI: 10.1021/Acs.Est.5B01499 |
0.626 |
|
| 2015 |
Squirewell EJ, Duffel MW. The effects of endoxifen and other major metabolites of tamoxifen on the sulfation of estradiol catalyzed by human cytosolic sulfotransferases hSULT1E1 and hSULT1A1*1. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 843-50. PMID 25819444 DOI: 10.1124/Dmd.115.063206 |
0.804 |
|
| 2015 |
Grimm FA, Hu D, Kania-Korwel I, Lehmler HJ, Ludewig G, Hornbuckle KC, Duffel MW, Bergman Å, Robertson LW. Metabolism and metabolites of polychlorinated biphenyls. Critical Reviews in Toxicology. 45: 245-72. PMID 25629923 DOI: 10.3109/10408444.2014.999365 |
0.638 |
|
| 2015 |
Grimm FA, Lehmler HJ, He X, Robertson LW, Duffel MW. Modulating inhibitors of transthyretin fibrillogenesis via sulfation: polychlorinated biphenyl sulfates as models. Chemico-Biological Interactions. 228: 1-8. PMID 25595224 DOI: 10.1016/J.Cbi.2015.01.002 |
0.654 |
|
| 2014 |
Squirewell EJ, Qin X, Duffel MW. Endoxifen and other metabolites of tamoxifen inhibit human hydroxysteroid sulfotransferase 2A1 (hSULT2A1). Drug Metabolism and Disposition: the Biological Fate of Chemicals. 42: 1843-50. PMID 25157097 DOI: 10.1124/Dmd.114.059709 |
0.802 |
|
| 2014 |
Ekuase EJ, Lehmler HJ, Robertson LW, Duffel MW. Binding interactions of hydroxylated polychlorinated biphenyls (OHPCBs) with human hydroxysteroid sulfotransferase hSULT2A1. Chemico-Biological Interactions. 212: 56-64. PMID 24508592 DOI: 10.1016/J.Cbi.2014.01.018 |
0.792 |
|
| 2013 |
Wu X, Duffel M, Lehmler HJ. Oxidation of polychlorinated biphenyls by liver tissue slices from phenobarbital-pretreated mice is congener-specific and atropselective. Chemical Research in Toxicology. 26: 1642-51. PMID 24107130 DOI: 10.1021/Tx400229E |
0.386 |
|
| 2013 |
Qin X, Lehmler HJ, Teesch LM, Robertson LW, Duffel MW. Chlorinated biphenyl quinones and phenyl-2,5-benzoquinone differentially modify the catalytic activity of human hydroxysteroid sulfotransferase hSULT2A1. Chemical Research in Toxicology. 26: 1474-85. PMID 24059442 DOI: 10.1021/Tx400207Q |
0.522 |
|
| 2013 |
Lehmler HJ, He X, Li X, Duffel MW, Parkin S. Effective synthesis of sulfate metabolites of chlorinated phenols. Chemosphere. 93: 1965-71. PMID 23906814 DOI: 10.1016/J.Chemosphere.2013.06.087 |
0.395 |
|
| 2013 |
Grimm FA, Lehmler HJ, He X, Robertson LW, Duffel MW. Sulfated metabolites of polychlorinated biphenyls are high-affinity ligands for the thyroid hormone transport protein transthyretin. Environmental Health Perspectives. 121: 657-62. PMID 23584369 DOI: 10.1289/Ehp.1206198 |
0.63 |
|
| 2013 |
Wu X, Kania-Korwel I, Chen H, Stamou M, Dammanahalli KJ, Duffel M, Lein PJ, Lehmler HJ. Metabolism of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) atropisomers in tissue slices from phenobarbital or dexamethasone-induced rats is sex-dependent. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 43: 933-47. PMID 23581876 DOI: 10.3109/00498254.2013.785626 |
0.391 |
|
| 2013 |
Qin X, Teesch LM, Duffel MW. Modification of the catalytic function of human hydroxysteroid sulfotransferase hSULT2A1 by formation of disulfide bonds. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 1094-103. PMID 23444386 DOI: 10.1124/Dmd.112.050534 |
0.526 |
|
| 2012 |
Dhakal K, He X, Lehmler HJ, Teesch LM, Duffel MW, Robertson LW. Identification of sulfated metabolites of 4-chlorobiphenyl (PCB3) in the serum and urine of male rats. Chemical Research in Toxicology. 25: 2796-804. PMID 23137097 DOI: 10.1021/Tx300416V |
0.361 |
|
| 2012 |
Dammanahalli JK, Duffel MW. Oxidative modification of rat sulfotransferase 1A1 activity in hepatic tissue slices correlates with effects on the purified enzyme. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 298-303. PMID 22041107 DOI: 10.1124/Dmd.111.042044 |
0.431 |
|
| 2011 |
Wu X, Pramanik A, Duffel MW, Hrycay EG, Bandiera SM, Lehmler HJ, Kania-Korwel I. 2,2',3,3',6,6'-Hexachlorobiphenyl (PCB 136) is enantioselectively oxidized to hydroxylated metabolites by rat liver microsomes. Chemical Research in Toxicology. 24: 2249-57. PMID 22026639 DOI: 10.1021/Tx200360M |
0.464 |
|
| 2011 |
Kania-Korwel I, Duffel MW, Lehmler HJ. Gas chromatographic analysis with chiral cyclodextrin phases reveals the enantioselective formation of hydroxylated polychlorinated biphenyls by rat liver microsomes. Environmental Science & Technology. 45: 9590-6. PMID 21966948 DOI: 10.1021/Es2014727 |
0.447 |
|
| 2011 |
Joshi SN, Vyas SM, Wu H, Duffel MW, Parkin S, Lehmler HJ. Regioselective Iodination of Chlorinated Aromatic Compounds Using Silver Salts. Tetrahedron. 67: 7461-7469. PMID 21918585 DOI: 10.1016/J.Tet.2011.07.064 |
0.316 |
|
| 2011 |
Ekuase EJ, Liu Y, Lehmler HJ, Robertson LW, Duffel MW. Structure-activity relationships for hydroxylated polychlorinated biphenyls as inhibitors of the sulfation of dehydroepiandrosterone catalyzed by human hydroxysteroid sulfotransferase SULT2A1. Chemical Research in Toxicology. 24: 1720-8. PMID 21913674 DOI: 10.1021/Tx200260H |
0.798 |
|
| 2011 |
Gulcan HO, Duffel MW. Substrate inhibition in human hydroxysteroid sulfotransferase SULT2A1: studies on the formation of catalytically non-productive enzyme complexes. Archives of Biochemistry and Biophysics. 507: 232-40. PMID 21187059 DOI: 10.1016/J.Abb.2010.12.027 |
0.771 |
|
| 2011 |
Liu Y, Lehmler HJ, Robertson LW, Duffel MW. Physicochemical properties of hydroxylated polychlorinated biphenyls aid in predicting their interactions with rat sulfotransferase 1A1 (rSULT1A1). Chemico-Biological Interactions. 189: 153-60. PMID 21130751 DOI: 10.1016/J.Cbi.2010.11.009 |
0.511 |
|
| 2010 |
Li X, Parkin S, Duffel MW, Robertson LW, Lehmler HJ. An efficient approach to sulfate metabolites of polychlorinated biphenyls. Environment International. 36: 843-8. PMID 19345419 DOI: 10.1016/J.Envint.2009.02.005 |
0.478 |
|
| 2009 |
Liu Y, Smart JT, Song Y, Lehmler HJ, Robertson LW, Duffel MW. Structure-activity relationships for hydroxylated polychlorinated biphenyls as substrates and inhibitors of rat sulfotransferases and modification of these relationships by changes in thiol status. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 1065-72. PMID 19196841 DOI: 10.1124/Dmd.108.026021 |
0.474 |
|
| 2009 |
Wangpradit O, Teesch LM, Mariappan SV, Duffel MW, Norstrom K, Robertson LW, Luthe G. Oxidation of 4-chlorobiphenyl metabolites to electrophilic species by prostaglandin H synthase. Chemical Research in Toxicology. 22: 64-71. PMID 19105592 DOI: 10.1021/Tx800300T |
0.428 |
|
| 2008 |
Gulcan HO, Liu Y, Duffel MW. Pentachlorophenol and other chlorinated phenols are substrates for human hydroxysteroid sulfotransferase hSULT2A1. Chemical Research in Toxicology. 21: 1503-8. PMID 18656962 DOI: 10.1021/Tx800133D |
0.759 |
|
| 2006 |
Liu Y, Apak TI, Lehmler HJ, Robertson LW, Duffel MW. Hydroxylated polychlorinated biphenyls are substrates and inhibitors of human hydroxysteroid sulfotransferase SULT2A1. Chemical Research in Toxicology. 19: 1420-5. PMID 17112228 DOI: 10.1021/TX060160+ |
0.554 |
|
| 2005 |
Sharma V, Duffel MW. A comparative molecular field analysis-based approach to prediction of sulfotransferase catalytic specificity. Methods in Enzymology. 400: 249-63. PMID 16399353 DOI: 10.1016/S0076-6879(05)00014-5 |
0.641 |
|
| 2004 |
Apak TI, Duffel MW. Interactions of the stereoisomers of alpha-hydroxytamoxifen with human hydroxysteroid sulfotransferase SULT2A1 and rat hydroxysteroid sulfotransferase STa. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 1501-8. PMID 15371299 DOI: 10.1124/Dmd.104.000919 |
0.321 |
|
| 2004 |
Sheng JJ, Saxena A, Duffel MW. Influence of phenylalanines 77 and 138 on the stereospecificity of aryl sulfotransferase IV. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 559-65. PMID 15100179 DOI: 10.1124/Dmd.32.5.559 |
0.696 |
|
| 2003 |
Sheng JJ, Duffel MW. Enantioselectivity of human hydroxysteroid sulfotransferase ST2A3 with naphthyl-1-ethanols. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 31: 697-700. PMID 12756199 DOI: 10.1124/Dmd.31.6.697 |
0.4 |
|
| 2002 |
Sharma V, Duffel MW. Comparative molecular field analysis of substrates for an aryl sulfotransferase based on catalytic mechanism and protein homology modeling. Journal of Medicinal Chemistry. 45: 5514-22. PMID 12459019 DOI: 10.1021/Jm010481C |
0.63 |
|
| 2001 |
Sheng JJ, Sharma V, Duffel MW. Measurement of aryl and alcohol sulfotransferase activity. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit4.5. PMID 20945296 DOI: 10.1002/0471140856.Tx0405S08 |
0.614 |
|
| 2001 |
Duffel MW, Marshal AD, McPhie P, Sharma V, Jakoby WB. Enzymatic aspects of the phenol (aryl) sulfotransferases. Drug Metabolism Reviews. 33: 369-95. PMID 11768773 DOI: 10.1081/Dmr-120001394 |
0.669 |
|
| 2001 |
Sheng JJ, Duffel MW. Bacterial expression, purification, and characterization of rat hydroxysteroid sulfotransferase STa Protein Expression and Purification. 21: 235-242. PMID 11162411 DOI: 10.1006/Prep.2000.1364 |
0.432 |
|
| 2000 |
Deshpande G, Schoenwald RD, Barfknecht CF, Duffel MW. In vitro and ex vivo hydrolysis rates of ethacrynate esters and their relationship to intraocular pressure in the rabbit eye. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 16: 539-56. PMID 11132901 DOI: 10.1089/Jop.2000.16.539 |
0.374 |
|
| 2000 |
King RS, Sharma V, Pedersen LC, Kakuta Y, Negishi M, Duffel MW. Structure-function modeling of the interactions of N-alkyl-N-hydroxyanilines with rat hepatic aryl sulfotransferase IV. Chemical Research in Toxicology. 13: 1251-8. PMID 11123966 DOI: 10.1021/Tx990184Z |
0.612 |
|
| 1999 |
Banoglu E, Duffel MW. Importance of peri-interactions on the stereospecificity of rat hydroxysteroid sulfotransferase STa with 1-arylethanols Chemical Research in Toxicology. 12: 278-285. PMID 10077491 DOI: 10.1021/Tx980219F |
0.436 |
|
| 1998 |
Shibutani S, Shaw PM, Suzuki N, Dasaradhi L, Duffel MW, Terashima I. Sulfation of α-hydroxytamoxifen catalyzed by human hydroxysteroid sulfotransferase results in tamoxifen-DNA adducts Carcinogenesis. 19: 2007-2011. PMID 9855017 DOI: 10.1093/Carcin/19.11.2007 |
0.323 |
|
| 1998 |
Duffel MW, Chen G, Sharma V. Studies on an affinity label for the sulfuryl acceptor binding site in an aryl sulfotransferase. Chemico-Biological Interactions. 109: 81-92. PMID 9566735 DOI: 10.1016/S0009-2797(97)00122-1 |
0.627 |
|
| 1997 |
Ahn SH, Duffel MW, Rosazza JPN. Oxidations of vincristine catalyzed by peroxidase and ceruloplasmin Journal of Natural Products. 60: 1125-1129. PMID 9392881 DOI: 10.1021/Np970226O |
0.385 |
|
| 1997 |
Banoglu E, Duffel MW. Studies on the interactions of chiral secondary alcohols with rat hydroxysteroid sulfotransferase STa Drug Metabolism and Disposition. 25: 1304-1310. PMID 9351908 |
0.338 |
|
| 1997 |
King RS, Duffel MW. Oxidation-dependent inactivation of aryl sulfotransferase IV by primary N-hydroxy arylamines during in vitro assays Carcinogenesis. 18: 843-849. PMID 9111223 DOI: 10.1093/Carcin/18.4.843 |
0.365 |
|
| 1996 |
Chen G, Banoglu E, Duffel MW. Influence of substrate structure on the catalytic efficiency of hydroxysteroid sulfotransferase STa in the sulfation of alcohols Chemical Research in Toxicology. 9: 67-74. PMID 8924618 DOI: 10.1021/Tx950065T |
0.422 |
|
| 1994 |
Duffel MW. Molecular specificity of aryl sulfotransferase IV (tyrosine-ester sulfotransferase) for xenobiotic substrates and inhibitors Chemico-Biological Interactions. 92: 3-14. PMID 8033263 DOI: 10.1016/0009-2797(94)90048-5 |
0.553 |
|
| 1992 |
Rosazza JP, Duffel MW, el-Marakby S, Ahn SH. Metabolism of the Catharanthus alkaloids: from Streptomyces griseus to monoamine oxidase B. Journal of Natural Products. 55: 269-84. PMID 1593278 DOI: 10.1021/Np50081A001 |
0.394 |
|
| 1992 |
Chen X, Yang YS, Zheng Y, Martin BM, Duffel MW, Jakoby WB. Tyrosine-ester sulfotransferase from rat liver: Bacterial expression and identification Protein Expression and Purification. 3: 421-426. PMID 1458056 DOI: 10.1016/S1046-5928(05)80045-2 |
0.357 |
|
| 1991 |
Rao SI, Duffel MW. Benzylic alcohols as stereospecific substrates and inhibitors for aryl sulfotransferase Chirality. 3: 104-111. PMID 1863522 DOI: 10.1002/Chir.530030205 |
0.434 |
|
| 1989 |
Gillespie SG, Duffel MW. Peroxidase as a model for reduction of tertiary amine oxides catalyzed by rat hepatic supernatant and microsomal fractions Biochemical Pharmacology. 38: 573-579. PMID 2917014 DOI: 10.1016/0006-2952(89)90201-3 |
0.365 |
|
| 1989 |
Elmarakby SA, Duffel MW, Rosazza JPN. In vitro metabolic transformations of vinblastine: Oxidations catalyzed by human ceruloplasmin Journal of Medicinal Chemistry. 32: 2158-2162. PMID 2769688 DOI: 10.1021/Jm00129A023 |
0.355 |
|
| 1989 |
Duffel MW, Binder TP, Rao SI. Assay of purified aryl sulfotransferase suitable for reactions yielding unstable sulfuric acid esters Analytical Biochemistry. 183: 320-324. PMID 2624319 DOI: 10.1016/0003-2697(89)90486-7 |
0.376 |
|
| 1988 |
Goswami A, Macdonald TL, Hubbard C, Duffel MW, Rosazza JP. Leurosine biotransformations: an unusual ring-fission reaction catalyzed by peroxidase. Chemical Research in Toxicology. 1: 238-42. PMID 2979738 DOI: 10.1021/Tx00004A009 |
0.338 |
|
| 1986 |
Duffel MW, Ing IS, Segarra TM, Dixson JA, Barfknecht CF, Schoenwald RD. N-Substituted sulfonamide carbonic anhydrase inhibitors with topical effects on intraocular pressure. Journal of Medicinal Chemistry. 29: 1488-94. PMID 3735316 DOI: 10.1021/Jm00158A028 |
0.353 |
|
| 1986 |
Duffel MW, Janss MN. Arylsulfotransferase IV catalyzed sulfation of 1-naphthalenemethanol Advances in Experimental Medicine and Biology. 197: 415-422. PMID 3464166 DOI: 10.1007/978-1-4684-5134-4_40 |
0.451 |
|
| 1986 |
Duffel MW, Jakoby WB. Cysteine S-conjugate N-acetyltransferase. Methods in Enzymology. 113: 516-20. PMID 3003508 DOI: 10.1016/S0076-6879(85)13069-7 |
0.426 |
|
| 1986 |
Duffel MW. Biochemical Pharmacology and Toxicology. Vol. I. Methodological Aspects of Drug Metabolizing Enzymes Journal of Pharmaceutical Sciences. 75: 727. DOI: 10.1002/Jps.2600750730 |
0.396 |
|
| 1984 |
Duffel MW, Gillespie SG. Microsomal Flavin‐Containing Monooxygenase Activity in Rat Corpus Striatum Journal of Neurochemistry. 42: 1350-1353. PMID 6707640 DOI: 10.1111/J.1471-4159.1984.Tb02794.X |
0.375 |
|
| 1981 |
Sekura RD, Duffel MW, Jakoby WB. [24] Aryl sulfotransferases Methods in Enzymology. 77: 197-206. PMID 6948989 DOI: 10.1016/S0076-6879(81)77026-5 |
0.371 |
|
| 1981 |
Duffel MW, Jakoby WB. On the mechanism of aryl sulfotransferase Journal of Biological Chemistry. 256: 11123-11127. PMID 6945304 |
0.364 |
|
| 1980 |
Ziegler DM, Poulsen LL, Duffel MW. Kinetic Studies On Mechanism And Substrate Specificity Of The Microsomal Flavin–Containing Monooxygenase Microsomes, Drug Oxidations and Chemical Carcinogenesis. 637-645. DOI: 10.1016/B978-0-12-187702-6.50005-0 |
0.432 |
|
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